Yamada Tsuyoshi 山田剛

… Alternative Names

山田剛ヤマダツヨシ

YAMADA Tsuyoshi 山田剛

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Researcher Number	80424331
Other IDs
Affiliation (Current)	2025: 帝京大学, 付置研究所, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 帝京大学, 付置研究所, 准教授 2015 – 2017: 帝京大学, 医真菌研究センター, 准教授 2011 – 2013: 帝京大学, 医真菌研究センター, 准教授 2007 – 2009: 帝京大学, 医真菌研究センター, 講師
Review Section/Research Field	Principal Investigator Basic Section 53050:Dermatology-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Bacteriology (including mycology) / Bacteriology (including Mycology) Except Principal Investigator Sections That Are Subject to Joint Review: Basic Section03060:Cultural assets study-related , Basic Section03070:Museology-related / Basic Section 03070:Museology-related / Basic Section 03060:Cultural assets study-related / Bacteriology (including Mycology)
Keywords	Principal Investigator 白癬 / 白癬菌 / 皮膚糸状菌 / 皮膚真菌症 / プロテアーゼ / dermatophytes / ABC transporters / azoles / antifungal resistance / Trichophyton rubrum … More / 制御因子 / 薬剤排出トランスポーター / 薬剤耐性 / 病態形成メカニズム / 整体防御回避 / 生体防御回避 / トリプシン / 痒み / マーカーリサイクルシステム / 分泌型セリンプロテアーゼ / 分泌型プロテアーゼ / flippase / marker recycling / serine proteases / 部位特異的組換え酵素 / マーカーリサイクリング / 病原因子 / 多重遺伝子族 / セリンプロテアーゼ / 感染症 … More Except Principal Investigator プロテオミクス / 実験考古学 / ツルマメ / 納豆系発酵食品 / 縄文時代 / アグロバクテリウム法 / 選択マーカ / プロテアーゼ / 白癬 / 遺伝子診断 / 遺伝子破壊 / 病原因子 / 形質転換 / 動物モデル / 白癬菌 / 病原性 Less

Elucidation of fermented natto-based foods in the Jomon period
- Principal Investigator
  
  中山誠二
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 03060:Cultural assets study-related
  Basic Section 03070:Museology-related
  Sections That Are Subject to Joint Review: Basic Section03060:Cultural assets study-related , Basic Section03070:Museology-related
- Research Institution
  Teikyo University
Establishment of therapeutic strategy for antifungal drug-resistant dermatophytosis based on control of drug efflux pumpsPrincipal Investigator
- Principal Investigator
  
  山田剛
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Teikyo University
Functions and roles of proteases in dermatophyte infection mechanismPrincipal Investigator
- Principal Investigator
  
  山田剛
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Teikyo University
Investigation of serine protease involved in proteinase-activated receptor 2-mediated itch in dermatophytosis.Principal Investigator
- Principal Investigator
  
  Yamada Tsuyoshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Teikyo University
A functional analysis of a secreted serine protease family for dermatophyte host invading mechanisms.Principal Investigator
- Principal Investigator
  
  YAMADA Tsuyoshi
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Teikyo University
The investigation on expression and regulation of pathogenic invasive gene in dermatophytes using new transformation system.
- Principal Investigator
  
  MAKIMURA Koichi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  Teikyo University

All 2023 2022 2021 2017 2013 2012 2009 2008 2007 Other

All Journal Article Presentation Patent Other

[Journal Article] Terbinafine resistance of Trichophyton clinical isolates caused by specific point mutations in the squalene epoxidase gene.2017
- Author(s)
  Yamada T, Maeda M, Alshahni MM, Tanaka R, Yaguchi T, Bontems O, Salamin K, Fratti M, Monod M.
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 61(7) Issue: 7
- DOI
  10.1128/aac.00115-17
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08472
[Journal Article] Enhanced gene replacements in Ku80 disruption mutants of the dermatophyte, Trichophyton mentagrophytes.2009
- Author(s)
  Yamada T, Makimura K, Hisajima T, Ishihara Y, Umeda Y, Abe S.
- Journal Title
  
  FEMS Microbiol Lett. 298(2)
  
  Pages: 208-17
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Direct Colony PCR of Several Medically Important Fungi using AmpdirectR Plus.2009
- Author(s)
  AlShahni MM, Makimura K, Yamada T, Satoh K, Ishihara Y, Takatori K, Sawada T
- Journal Title
  
  Japanese Journal of Infectious Diseases 62(2)
  
  Pages: 164-167
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Enhanced gene replacements in Ku80 disruption mutants of the dermatophyt e, Trichophyton mentagrophytes.2009
- Author(s)
  Yamada T
- Journal Title
  
  FEMS Microbiol Lett. 298(2)
  
  Pages: 208-217
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Agrobacterium tumefaciens-mediated transformation of the dermatophyte, Trichophyton mentagrophytes: an efficient tool for gene transfer.2009
- Author(s)
  Yamada T, Makimura K, Satoh K, Umeda Y, Ishihara Y, Abe S
- Journal Title
  
  Medical Mycology 47(5
  
  Pages: 485-494
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Agrobacterium tumefaciens-mediated transformation of the dermato phyte, Trichophyton mentagrophytes : an efficient tool for gene transfer.2009
- Author(s)
  Yamada T
- Journal Title
  
  Medical Mycology 47(5)
  
  Pages: 485-494
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Nourseothricin acetyltransferase: a new dominant selectable marker for the dermatophyte Trichophyton mentagrophytes.2009
- Author(s)
  Alshahni M, Makimura K, Yamada T, Takatori K, Sawada T.
- Journal Title
  
  Medical Mycology (in press)
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Genetic transformation of the dermatophyte, Trichophyton mentagrophytes, based on the use of G418 resistance as a dominant selectable marker2008
- Author(s)
  Tsuyoshi Yamada, Koichi Makimura, Tatsuya Hisajima Maki Ito, Yoshiko Umeda, Shigeru Abe
- Journal Title
  
  Journal of Dermatological Science 49
  
  Pages: 53-61
- NAID
  10024118229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Genetic transformation of the dermatophyte, Trichophyton mentagrophytes, based on the use of G418 resistance as a dominant selectable marker2008
- Author(s)
  Yamada T, Makimura K, Hisajima T, Ito M, Umeda Y, Abe S
- Journal Title
  
  Journal of Dermatological Science 49(1)
  
  Pages: 53-61
- NAID
  10024118229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Protective effects of farnesol against oral candidiasis in mice.2008
- Author(s)
  Hisajima T, Maruyama N, Tanabe Y, Ishibashi H, Yamada T, Makimura K, Nishiyama Y, Funakoshi K, Oshima H, Abe S
- Journal Title
  
  Microbiology and Immunology 52(7)
  
  Pages: 327-33
- NAID
  10027684449
- Data Source
  KAKENHI-PROJECT-19590457
[Journal Article] Genetic transformation of the dermatophyte, Trichophyton mentagrophytes, based on the use of G418 resistance as a dominant selectable marker.2008
- Author(s)
  Yamada T, Makimura K, Hisajima T, Ito M, Umeda Y, Abe S
- Journal Title
  
  Journal of Dermatological Science 49(1)
  
  Pages: 53-61
- NAID
  10024118229
- Data Source
  KAKENHI-PROJECT-19590457
[Patent] 遺伝子破壊白癬菌2008
- Inventor(s)
  槇村浩一、山田剛、安部茂
- Industrial Property Rights Holder
  槇村浩一、山田剛、安部茂
- Industrial Property Number
  2008-011432
- Filing Date
  2008-04-22
- Data Source
  KAKENHI-PROJECT-19590457
[Presentation] 白癬菌Trichophyton indotineaeで見つかったアゾール系抗真菌薬に対する新たな低感受性化のメカニズム2023
- Author(s)
  山田剛、矢口貴志
- Organizer
  日本細菌学会
- Data Source
  KAKENHI-PROJECT-20K07054
[Presentation] 白癬菌とあおの薬剤耐性化機序: 新種の白癬菌で見つかった病原真菌の新たな薬剤耐性機序を中心に2022
- Author(s)
  山田剛
- Organizer
  日本医真菌学会
- Data Source
  KAKENHI-PROJECT-20K07054
[Presentation] 白癬菌の薬剤耐性化の現状とそのメカニズムについて2021
- Author(s)
  山田剛
- Organizer
  第120回日本皮膚科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07054
[Presentation] 白癬菌の薬剤耐性化の現状とそのメカニズムについて2021
- Author(s)
  山田剛
- Organizer
  第65回日本医真菌学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-20K07054
[Presentation] スイス・ローザンヌで分離された複数のテルビナフィン低感受性白癬菌株と薬剤感受性低下要因の解析2017
- Author(s)
  山田剛, Mohamed Mahdi Alshahni, 田中玲子, 矢口貴志
- Organizer
  第61回日本医真菌学会学術集会
- Data Source
  KAKENHI-PROJECT-15K08472
[Presentation] Basic and applied studies on dermatophytes and tinea infection2013
- Author(s)
  Yamada T, Abe S
- Organizer
  第86回日本細菌学会総会
- Place of Presentation
  幕張メッセ（千葉）
- Data Source
  KAKENHI-PROJECT-23590520
[Presentation] 白癬菌における銅イオン応答性プロモーターを用いた遺伝子発現調節系の構築2012
- Author(s)
  岩田淳, 槇村浩一, 安部茂, 山田剛
- Organizer
  第55回日本医真菌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23590520
[Presentation] Development of a conditional gene knockdown system based on copper-responsive promoter PCTR4.2012
- Author(s)
  Iwata A, Alshahni MM, Nishiyama Y, Makimura K, Abe S, Yamada T
- Organizer
  The 18th Congress of the International Society for Human and Animal Mycology
- Place of Presentation
  Berlin (Germany)
- Data Source
  KAKENHI-PROJECT-23590520
[Presentation] 白癬菌における銅イオン応答性プロモーターを用いた遺伝子発現調節系の構築2012
- Author(s)
  岩田淳、槇村浩一、安部茂、山田剛
- Organizer
  第56回日本医真菌学会総会
- Place of Presentation
  京王プラザ多摩（東京）
- Data Source
  KAKENHI-PROJECT-23590520
[Presentation] Development of a conditional gene knockdown system based on copper-responsive promoter PCTR42012
- Author(s)
  岩田淳, Mahdi Mohamed Alshahni, 西山彌生, 槇村浩一, 安部茂, 山田剛
- Organizer
  The 18th Congress of the International Society for Human and Animal Mycology
- Place of Presentation
  Berlin
- Data Source
  KAKENHI-PROJECT-23590520
[Presentation] アグロバクテリウム法を用いた白癬菌遺伝子破壊株の作出2009
- Author(s)
  山田剛, 槇村浩一, 安部茂
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-19590457
[Presentation] 長期ステロイド剤外用後に生じた皮膚フサリウム症の一例2009
- Author(s)
  山田陽三
- Organizer
  第108回日本皮膚科学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-19590457
[Presentation] Enhanced gene replacements in Ku80 disruption metants of the dermatophyte, Trichophyton mentagrophytes.2009
- Author(s)
  Tsuyoshi Yamada
- Organizer
  The International Society for Human and Animal Mycology 2009
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19590457
[Presentation] アグロバクテリウム法を用いた白癬菌形質転換体作出の試み2008
- Author(s)
  山田剛, 愼村浩一, 安部茂
- Organizer
  第81回日本細菌学会総会
- Place of Presentation
  国立京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-19590457
[Presentation] アグロバクテリウム法を用いた白癖菌遺伝子破壊株の作出について2008
- Author(s)
  山田剛, 槇村浩一, 安部茂
- Organizer
  第52回日本医真菌学会総会
- Place of Presentation
  長崎大学
- Data Source
  KAKENHI-PROJECT-19590457
[Presentation] Development of Analyzing System for Microbial Flora on board Space Station and Astronauts.2007
- Author(s)
  Koichi MAKIMURA, Kazuo SATOH, Tsuyoshi YAMADA, Yayoi NISHIYAMA, Shigeru ABE, Yuuji TSUKII, Takashi SUGITA, Kosuke TAKATORI, Yoshimi BENNO, Takashi YAMAZAKI
- Organizer
  The 5th ISLSWG International Workshop on Space Microbiology
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-19590457
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1. MAKIMURA Koichi (00266347)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NISHIYAMA Yayoi (10082231)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. ABE Shigeru (10125974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. ANDOH Tsugunobu (50333498)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TANAKA Reiko (60143319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 鈴木章一 (40253695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 矢口貴志 (60361440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 中山誠二 (60574142)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高橋宣治 (00236291)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 西内巧 (20334790)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 榎元廣文 (30609392)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 加納塁 (00318388)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. FURUKAWA Nayuta

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 槙村浩一

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results

Yamada Tsuyoshi 山田 剛

山田 剛 ヤマダ ツヨシ

YAMADA Tsuyoshi 山田 剛

Research Projects

Research Products

Co-Researchers

Elucidation of fermented natto-based foods in the Jomon period

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of therapeutic strategy for antifungal drug-resistant dermatophytosis based on control of drug efflux pumpsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functions and roles of proteases in dermatophyte infection mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of serine protease involved in proteinase-activated receptor 2-mediated itch in dermatophytosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A functional analysis of a secreted serine protease family for dermatophyte host invading mechanisms.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The investigation on expression and regulation of pathogenic invasive gene in dermatophytes using new transformation system.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Terbinafine resistance of Trichophyton clinical isolates caused by specific point mutations in the squalene epoxidase gene.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Enhanced gene replacements in Ku80 disruption mutants of the dermatophyte, Trichophyton mentagrophytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Direct Colony PCR of Several Medically Important Fungi using AmpdirectR Plus.2009

Author(s)

Journal Title

Data Source

[Journal Article] Enhanced gene replacements in Ku80 disruption mutants of the dermatophyt e, Trichophyton mentagrophytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Agrobacterium tumefaciens-mediated transformation of the dermatophyte, Trichophyton mentagrophytes: an efficient tool for gene transfer.2009

Author(s)

Journal Title

Data Source

[Journal Article] Agrobacterium tumefaciens-mediated transformation of the dermato phyte, Trichophyton mentagrophytes : an efficient tool for gene transfer.2009

Author(s)

Journal Title

Data Source

[Journal Article] Nourseothricin acetyltransferase: a new dominant selectable marker for the dermatophyte Trichophyton mentagrophytes.2009

Author(s)

Journal Title

Data Source

[Journal Article] Genetic transformation of the dermatophyte, Trichophyton mentagrophytes, based on the use of G418 resistance as a dominant selectable marker2008

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Genetic transformation of the dermatophyte, Trichophyton mentagrophytes, based on the use of G418 resistance as a dominant selectable marker2008

Author(s)

Journal Title

NAID

Yamada Tsuyoshi 山田剛

山田剛ヤマダツヨシ

YAMADA Tsuyoshi 山田剛