Shima Yuichi 嶋雄一

… Alternative Names

SHIMA Yuichi 嶋雄一

Less

Researcher Number	80425420
Other IDs
Affiliation (Current)	2025: 久留米大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2021 – 2023: 久留米大学, 医学部, 教授 2019 – 2020: 川崎医科大学, 医学部, 教授 2016 – 2017: 川崎医科大学, 医学部, 准教授 2015: 九州大学, 大学院医学研究院, 講師 2011 – 2015: 九州大学, 医学(系)研究科(研究院), 助教 … More 2011: 九州大学, 大学院・医学研究院, 助教 2010: Kyushu University, 医学研究院, 助教 2009: Kyushu University, 大学院・医学研究院, 助教 2006 – 2007: 基礎生物学研究所, 性差生物学研究部門, 特別協力研究員 Less
Review Section/Research Field	Principal Investigator Biological Sciences / General medical chemistry / Basic Section 48040:Medical biochemistry-related / Endocrinology Except Principal Investigator Biological Sciences / General medical chemistry
Keywords	Principal Investigator ライディッヒ細胞 / 精巣 / 男性ホルモン / 分化 / エンハンサー / 発生 / 精子形成 / 核内受容体 / テストステロン / 転写 … More / mini puberty / 脱分化 / トランスクリプトーム / 幹細胞 / トランスジェニックマウス / SF-1 / Ad4BP / mini-puberty / 精子形成幹細胞 / 下垂体 / ゴナドトロピン / 転写制御 / エピジェネティック / クロマチン構造解析 / 遺伝子発現解析 / 単一細胞解析 / DNAメチル化 / 分化記憶 / 発生・分化 / クロマチン免疫沈降 / ニューロン / 神経 / 性行動 / 視床下部 / ステロイドホルモン / ノックアウトマウス / 性分化 / ニッチ / 内分泌 / マイクロアレイ / 発現制御 / ゲノム / 遺伝子 / 性分化異常症 / Leydig細胞 / 脳下垂体 / 生殖腺 … More Except Principal Investigator 発生 / 遺伝子発現 / トランスジェニック / 性差 / 卵巣 / 性特異的エンハンサー / 性差構築 / 発生・分化 / 発現制御 / セルトリ細胞 / ライディッヒ細胞 / 精巣 / クロマチン構造 / ゲノム / development / adrenal cortex / steroid hormone / adrenal gland / tissue specificity / gene expression / enhancer / 副腎皮質 / ステロイドホルモン / 副腎 / 組織特異性 / エンハンサー Less

Elucidation of the physiological significance of mini-puberty based on single-cell analysis of neonatal testisPrincipal Investigator
- Principal Investigator
  
  嶋雄一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kurume University
Elucidation of the importance of mini-puberty on spermatogenesisPrincipal Investigator
- Principal Investigator
  
  嶋雄一
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kurume University
Elucidation of the molecular basis of fetal differentiation memory retention in testicular Leydig cellsPrincipal Investigator
- Principal Investigator
  
  Shima Yuichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48040:Medical biochemistry-related
- Research Institution
  Kurume University
  Kawasaki Medical School
精子形成を可能とする精巣間質組織の再構築機構とその破綻Principal Investigator
- Principal Investigator
  
  嶋雄一
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kawasaki Medical School
Analyses of gene regulatory network in VMH underlying female sexual behaviorPrincipal Investigator
- Principal Investigator
  
  Shima Yuichi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
胎仔型ライディッヒ細胞による精子形成幹細胞ニッチ形成機構の解明Principal Investigator
- Principal Investigator
  
  嶋雄一
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Identification of novel biological functions of fetal Leydig cellsPrincipal Investigator
- Principal Investigator
  
  SHIMA YUICHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
Establishment of sex differences through sex-specific enhancer
- Principal Investigator
  
  MOROHASHI Ken-ichirou
- Project Period (FY)
  2010 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Identification of the mechanisms of the fetal Leydig cell differentiationPrincipal Investigator
- Principal Investigator
  
  SHIMA Yuichi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
生殖腺と脳下垂体特異的遺伝子発現調節領域の解析を基盤とする性分化異常症の解明Principal Investigator
- Principal Investigator
  
  嶋雄一
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Endocrinology
- Research Institution
  National Institute for Basic Biology
Mechanism of adrenocortical development
- Principal Investigator
  
  MOROHASHI Ken-ichirou
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Kyushu University
  National Institute for Basic Biology

[Journal Article] Mini-pubertyとオス生殖機能の成熟2023
- Author(s)
  嶋雄一、鈴木堅太郎
- Journal Title
  
  月刊「細胞」
  
  Volume: 55 Pages: 34-37
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Journal Article] Tmsb10 triggers fetal Leydig differentiation by suppressing the RAS/ERK pathway.2022
- Author(s)
  Miki Inoue, Takashi Baba, Fumiya Takahashi, Miho Terao, Shogo Yanai, Yuichi Shima, Daisuke Saito, Kei Sugihara, Takashi Miura, Shuji Takada, Mikita Suyama, Yasuyuki Ohkawa, Ken-Ichirou Morohashi.
- Journal Title
  
  Commun Biol.
  
  Volume: 5 Issue: 1 Pages: 974-974
- DOI
  10.1038/s42003-022-03941-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19275, KAKENHI-PROJECT-20H00456, KAKENHI-PROJECT-20H03436, KAKENHI-PROJECT-20K08863, KAKENHI-PUBLICLY-21H00232, KAKENHI-PUBLICLY-21H00235, KAKENHI-PUBLICLY-22H04676, KAKENHI-PLANNED-17H06427, KAKENHI-PROJECT-22H04993
[Journal Article] Correlative volume-imaging using combined array tomography and FIB-SEM tomography with beam deceleration for 3D architecture visualization in tissue2022
- Author(s)
  Hirashima Shingo、Ohta Keisuke、Rikimaru-Nishi Yukiko、Togo Akinobu、Funatsu Takashi、Tsuneyoshi Risa、Shima Yuichi、Nakamura Kei-ichiro
- Journal Title
  
  Microscopy
  
  Volume: - Issue: 3 Pages: 187-192
- DOI
  10.1093/jmicro/dfac015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K11733, KAKENHI-PROJECT-20K18469, KAKENHI-PROJECT-20K06730, KAKENHI-PROJECT-20H03290, KAKENHI-PUBLICLY-21H00235
[Journal Article] 精巣ライディッヒ細胞の分化と男性生殖機能の発達2022
- Author(s)
  嶋雄一
- Journal Title
  
  久留米医学会雑誌
  
  Volume: 85 Pages: 139-145
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Journal Article] Functional Importance of Mini-Puberty in Spermatogenic Stem Cell Formation2022
- Author(s)
  Shima Yuichi
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 10 Pages: 907989-907989
- DOI
  10.3389/fcell.2022.907989
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Journal Article] Intronic Enhancer Is Essential for Nr5a1 Expression in the Pituitary Gonadotrope and for Postnatal Development of Male Reproductive Organs in a Mouse Model2022
- Author(s)
  Shima Yuichi、Miyabayashi Kanako、Mori Takami、Ono Koji、Kajimoto Mizuki、Cho Hae Lim、Tsuchida Hitomi、Uenoyama Yoshihisa、Tsukamura Hiroko、Suzuki Kentaro、Choi Man Ho、Toida Kazunori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 1 Pages: 192-192
- DOI
  10.3390/ijms24010192
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06932, KAKENHI-PROJECT-21K19186, KAKENHI-PUBLICLY-21H00235, KAKENHI-PROJECT-21H05031
[Journal Article] Generation of ovarian follicles from mouse pluripotent stem cells2021
- Author(s)
  Yoshino Takashi、Suzuki Takahiro、Nagamatsu Go、Yabukami Haruka、Ikegaya Mika、Kishima Mami、Kita Haruka、Imamura Takuya、Nakashima Kinichi、Nishinakamura Ryuichi、Tachibana Makoto、Inoue Miki、Shima Yuichi、Morohashi Ken-ichirou、Hayashi Katsuhiko
- Journal Title
  
  Science
  
  Volume: 373 Issue: 6552 Pages: 282-289
- DOI
  10.1126/science.abe0237
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07378, KAKENHI-PLANNED-18H05545, KAKENHI-PUBLICLY-21H00235, KAKENHI-PROJECT-21H04769, KAKENHI-PROJECT-19H03138, KAKENHI-PROJECT-21K19221, KAKENHI-PROJECT-20H03436, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-17H06427, KAKENHI-ORGANIZER-18H05544, KAKENHI-PROJECT-19K06678
[Journal Article] Testosterone regulates the emission of ultrasonic vocalizations and mounting behavior during different developmental periods in mice2020
- Author(s)
  Kikusui Takefumi、Shima Yuichi、Sonobe Miku、Yoshida Yuuki、Nagasawa Miho、Nomoto Kensaku、Mogi Kazutaka
- Journal Title
  
  Developmental Psychobiology
  
  Volume: 0 Issue: 4 Pages: 0-0
- DOI
  10.1002/dev.22045
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07378, KAKENHI-PUBLICLY-20H04932, KAKENHI-PROJECT-19K22373, KAKENHI-PROJECT-18H02356
[Journal Article] Development of fetal and adult Leydig cells.2019
- Author(s)
  Yuichi Shima
- Journal Title
  
  Reproductive Medicine and Biology
  
  Volume: 18 Issue: 4 Pages: 323-330
- DOI
  10.1002/rmb2.12287
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07378
[Journal Article] Differential lactate and cholesterol synthetic activities in XY and XX Sertoli cells.2017
- Author(s)
  Shishido Y, Baba T, Sato T, Shima Y, Miyabayashi K, Inoue M, Akiyama H, Kimura H, Kanal Y, Ishihara Y, Haraguchi S, Miyazaki A, Rozman D, Yamazaki T, Choi MH, Ohkawa Y, Suyama M, Morohashi KI
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 41912-41912
- DOI
  10.1038/srep41912
- NAID
  120006799381
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01255, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-15K18571, KAKENHI-PROJECT-16K08593, KAKENHI-PROJECT-17K00569, KAKENHI-PLANNED-17H06427, KAKENHI-PROJECT-16H05142, KAKENHI-PUBLICLY-16H01251
[Journal Article] Leydig progenitor cells in fetal testis.2017
- Author(s)
  Shima Y, Morohashi KI
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 445 Pages: 55-64
- DOI
  10.1016/j.mce.2016.12.006
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Journal Article] Role of Ad4-binding protein/steroidogenic factor 1 in regulating NADPH production in adrenocortical Y-1 cells2017
- Author(s)
  Li B, BabaT, Miyabayashi K, Sato T, Shima Y, Ichinose T, Miura D, Ohkawa Y, Suyama M, Morohashi KI
- Journal Title
  
  Endocr J
  
  Volume: 64 Issue: 3 Pages: 315-324
- DOI
  10.1507/endocrj.EJ16-0467
- NAID
  130005529460
- ISSN
  0918-8959, 1348-4540
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-16H01255, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26462066, KAKENHI-PROJECT-16K08593, KAKENHI-PROJECT-26713020
[Journal Article] Neuregulin 1 Regulates Proliferation of Leydig Cells to Support Spermatogenesis and Sexual Behavior in Adult Mice.2016
- Author(s)
  Umehara T, Kawashima I, Kawai T, Hoshino Y, Morohashi KI, Shima Y, Zeng W, Richard JS, Shimada M
- Journal Title
  
  Endocrinology
  
  Volume: 157 Pages: 4899-4913
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Journal Article] SF-1 deficiency causes lipid accumulation in Leydig cells via suppression of STAR and CYP11A1.2016
- Author(s)
  Hatano M, Migita T, Ohishi T, Shima Y, Ogawa Y, Morohashi KI, Hasegawa Y, Shibasaki F
- Journal Title
  
  Endocrine
  
  Volume: 54 Pages: 484-496
- NAID
  40021080281
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Journal Article] 精巣におけるテストステロン産生と性分化2016
- Author(s)
  嶋　雄一、諸橋　憲一郎
- Journal Title
  
  アンチエイジング医学
  
  Volume: 12 Pages: 22-27
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Journal Article] solation and characterization of mouse fetal Leydig progenitor cells2016
- Author(s)
  Miki Inoue, Yuichi Shima, Kanako Miyabayashi, Tetsuya Sato, Takashi Baba, Yasuyuki Ohkawa, Haruhiko Akiyama, Mikita Suyama, Ken-ichirou Morohashi
- Journal Title
  
  Endocrinology
  
  Volume: 157 Issue: 3 Pages: 1222-1233
- DOI
  10.1210/en.2015-1773
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22132002, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-16H05142
[Journal Article] Heterogeneity of ovarian theca and interstitial gland cells in mice2015
- Author(s)
  Kanako Miyabayashi, Kaori Tokunaga, Hiroyuki Otake, Takashi Baba, Yuichi Shima, Ken-ichirou Morohashi
- Journal Title
  
  PLoS One
  
  Volume: 10
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-22132002
[Journal Article] Fetal Leydig Cells are Androgen Independent and Persist as an Androgen-independent Subpopulation in the Postnatal Testis2015
- Author(s)
  Yuichi Shima, Sawako Matsuzaki, Kanako Miyabayashi, Hiroyuki Otake, Takashi Baba, Shigeaki Kato, Ilpo Huhtaniemi, Ken-ichirou Morohashi
- Journal Title
  
  Mol Endocrinol
  
  Volume: 29 Issue: 11 Pages: 1581-1593
- DOI
  10.1210/me.2015-1200
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22132002, KAKENHI-PROJECT-26670145
[Journal Article] 出生後の清掃における胎仔型ライディッヒ細胞の細胞運命と生理機能の解明2014
- Author(s)
  嶋雄一、宮林香奈子、松崎佐和子、井上実紀、諸橋憲一郎
- Journal Title
  
  日本生殖内分泌学会雑誌
  
  Volume: 19 Pages: 45-50
- Data Source
  KAKENHI-PROJECT-26670145
[Journal Article] Glycolytic gene as the targets of nuclear receptor Ad4BP/SF-12014
- Author(s)
  Takashi Baba, Hiroyuki Otake, Tetsuya Sato, Kanako Miyabayashi, Yurina Shishido, Chia-Yih Wang, Yuichi Shima, Hiroshi Kimura, Mikako Yagi, Yasuhiro Ishihara, Shinjiro Hino, Hidesato Ogawa, Mitsuyoshi Nakao, Takeshi Yamazaki, Dongchon, Kang, Yasuyuki Ohkawa, Mikita Suyama, Bon-Chu Chung, Ken-ichirou Morohashi
- Journal Title
  
  Nature Commun
  
  Volume: 5 Issue: 1 Pages: 3634-3634
- DOI
  10.1038/ncomms4634
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-22132002, KAKENHI-PLANNED-22132005, KAKENHI-PLANNED-23116009, KAKENHI-PROJECT-23590339, KAKENHI-PLANNED-25116005, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-25340047, KAKENHI-PROJECT-25430178, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26440015, KAKENHI-PROJECT-26670145, KAKENHI-PROJECT-26860194
[Journal Article] Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells2013
- Author(s)
  Kanako Miyabayashi, Yuko Katoh-Fukui, Hidesato Ogawa, Takashi Baba, Yuichi Shima, Noriyuki Sugiyama, Kunio Kitamura, Ken-ichirou Morohashi
- Journal Title
  
  PLOS One
  
  Volume: 8
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22132002
[Journal Article] 性ホルモン産生細胞の性差2013
- Author(s)
  嶋　雄一、諸橋　憲一郎
- Journal Title
  
  細胞工学
  
  Volume: 32 Pages: 158-163
- Data Source
  KAKENHI-PUBLICLY-23116707
[Journal Article] Aristaless related homeobox gene Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells2013
- Author(s)
  Miyabayashi K, Katoh-Fukui Y, Ogawa H, Baba T, Shima Y, Sugiyama N, Kitamura K, Morohashi K
- Journal Title
  
  PLoS ONE
  
  Volume: 8 Issue: 6 Pages: e68050-e68050
- DOI
  10.1371/journal.pone.0068050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590339, KAKENHI-PROJECT-23591197
[Journal Article] 性ホルモン産生細胞の性差2013
- Author(s)
  嶋　雄一、諸橋　憲一郎
- Journal Title
  
  細胞工学
  
  Volume: 32 Pages: 158-163
- Data Source
  KAKENHI-PROJECT-23590339
[Journal Article] Contribution of Leydig and Sertoli cells to testosterone production in mouse fetal testes2013
- Author(s)
  Yuichi Shima
- Journal Title
  
  Molecular Endocrinology
  
  Volume: 27 Issue: 1 Pages: 63-73
- DOI
  10.1210/me.2012-1256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J10683, KAKENHI-PLANNED-22132002, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-22590273, KAKENHI-PROJECT-23590339, KAKENHI-ORGANIZER-22132001, KAKENHI-PUBLICLY-23116707
[Journal Article] 性ホルモン産生細胞の性差2013
- Author(s)
  嶋雄一, 諸橋憲一郎
- Journal Title
  
  細胞工学
  
  Volume: 32巻2号 Pages: 158-163
- Data Source
  KAKENHI-PROJECT-23590339
[Journal Article] Cbx2, a polycomb group gene, is required for Sry gene expression in mice.2012
- Author(s)
  Katoh-Fukui Y, Miyabayashi K, Komatsu T, Owaki A, Baba T., Shima, Y, Kidokoro T, Kanai Y, Schedl A, Wilhelm D, Koopman P, Okuno Y, Morohashi K.
- Journal Title
  
  Endocrinology
  
  Volume: 153(2) Issue: 2 Pages: 913-924
- DOI
  10.1210/en.2011-1055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21248034, KAKENHI-PROJECT-21590354, KAKENHI-PLANNED-22132002, KAKENHI-PUBLICLY-23116707, KAKENHI-PUBLICLY-23132504, KAKENHI-PROJECT-23590339, KAKENHI-ORGANIZER-22132001
[Journal Article] SF-1 expression during adrenal development and tumorigenesis2011
- Author(s)
  Gardine JR, 他3名(3番目)
- Journal Title
  
  Mol Cell Endocrinol
  
  Volume: 351 Issue: 1 Pages: 12-8
- DOI
  10.1016/j.mce.2011.10.007
- Data Source
  KAKENHI-PUBLICLY-23116707, KAKENHI-PROJECT-23590339
[Journal Article] Identification of enhancer specific for fetal Leydig cells in Ad4BP/SF-1 gene2011
- Author(s)
  Yuichi Shima, et al
- Journal Title
  
  Endocrinology
  
  Volume: 153 Issue: 1 Pages: 417-425
- DOI
  10.1210/en.2011-1407
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249018, KAKENHI-PLANNED-22132002, KAKENHI-PUBLICLY-23116707, KAKENHI-PROJECT-23590339, KAKENHI-ORGANIZER-22132001
[Journal Article] DNA methylation of intronic enhancers directs tissue-specific expression of Steroidogenic Factor 1/Adrenal 4 Binding Protein (SF-1/Ad4BP)2011
- Author(s)
  Erling A.Hoivik, et al
- Journal Title
  
  Endocrinology
  
  Volume: 152 Issue: 5 Pages: 2100-2112
- DOI
  10.1210/en.2010-1305
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249018, KAKENHI-PROJECT-21390067, KAKENHI-PLANNED-22126005, KAKENHI-PLANNED-22132002, KAKENHI-PUBLICLY-23116707, KAKENHI-PROJECT-23590339
[Journal Article] Methylation of Intronic Enhancers Directs Tissue-Specific Expression of Steroidogenic Factor 1/Adrenal 4 Binding Protein(SF-1/Ad4BP).2011
- Author(s)
  Hoivik EA, Bjanesoy TE, Mai O, Okamoto S, Minokoshi Y, Shima Y, Morohashi K, Bohem U, Bakke M
- Journal Title
  
  Endocrinology Epub ahead of print
- Data Source
  KAKENHI-PROJECT-21790284
[Journal Article] エネルギー代謝とその調節機序エネルギー代謝に関わる因子転写因子Ad4BP/SF-12010
- Author(s)
  嶋雄一、諸橋憲一郎
- Journal Title
  
  日本臨床 68(2)
  
  Pages: 200-204
- Data Source
  KAKENHI-PROJECT-21790284
[Journal Article] エネルギー代謝とその調節機序エネルギー代謝にかかわる因子転写因子Ad4BP/SF-12010
- Author(s)
  嶋雄一、諸橋憲一郎
- Journal Title
  
  日本臨床 68巻増刊号2号
  
  Pages: 200-204
- Data Source
  KAKENHI-PROJECT-21790284
[Journal Article] Abnormal epithelial cell polarity and ectopic epidermal growth factor receptor(EGFR)expression induced in Emx2 KO embryonic gonads.2010
- Author(s)
  Kusaka M, Katoh-Fukui Y, Ogawa H, Miyabayashi K, Baba T, Shima Y, Sugiyama N, Sugimoto Y, Okuno Y, Kodama R, Iizuka-Kogo A, Senda T, Sasaoka T, Kitamura K, Aizawa S, Morohashi K
- Journal Title
  
  Endocrinology. 151(12)
  
  Pages: 5893-904
- NAID
  120005227384
- Data Source
  KAKENHI-PROJECT-21790284
[Journal Article] Mechanism of asymmetric ovarian development in chick embryos2008
- Author(s)
  Y., Ishimaru, T., Komatsu, M., Kasahara, Y., Katoh-Fukui, H., Ogawa, Y., Toyama, M., Maekawa, K., Toshimori, R.A.S., Chandraratna, K., Morohashi, H., Yoshioka
- Journal Title
  
  Development 135
  
  Pages: 677-685
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Journal Article] Mechanism of asymmetric ovazian development in chick embryos2008
- Author(s)
  Y.lshimaru, et. al.
- Journal Title
  
  Development 135
  
  Pages: 677-685
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390091
[Journal Article] Mechanism of asymmetric ovarian development in chick embryos2008
- Author(s)
  Y.Ishimaru, et. al.
- Journal Title
  
  Development 135
  
  Pages: 677-685
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390091
[Journal Article] Pitx2 regulates Ad4BP/SF-1 gene transcription in the pituitary gonadotrope through interaction with the intronic enhancer.2008
- Author(s)
  嶋雄一, 他8名(1番目)
- Journal Title
  
  Molecular Endocrinology (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18790644
[Journal Article] Hypogonadotropic hypogonadism in an adult female with a heterozygous hypomorphic mutation of SOX22007
- Author(s)
  N., Sato, Y., Kamachi, H., Kondoh, Y., Shima, K., Morohashi, R., Horikawa, T., Ogata
- Journal Title
  
  Eur. J. Endocrinol. 156
  
  Pages: 169-173
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Journal Article] Hypogonadotropic hypogonadism in an adult female with a heterozygous hypomorphic mutation of SOX2.2007
- Author(s)
  N.Sato, Y.Kamachi, H.Kondoh, Y.Shima, K.Morohashi, R.Horikawa, T.Ogata.
- Journal Title
  
  Eur.J.Endocrinol. 156
  
  Pages: 169-173
- Data Source
  KAKENHI-PROJECT-18390091
[Journal Article] Differential gene dosage effects of Ad4BP/SF-1 on target tissue development. Biochem.Biophys2006
- Author(s)
  Fatchiyah, M., Zubair, Y., Shima, S., Oka, S., Ishihara, Y., Fukui-Katoh, K.Morohashi
- Journal Title
  
  Res.Commun. 341
  
  Pages: 1036-1045
- Data Source
  KAKENHI-PROJECT-18390091
[Journal Article] Differential gene dosage effects of Ad4BP/SF-1 on target tissue development2006
- Author(s)
  Fatchiyah, M., Zubair, Y., Shima, S., Oka, S., Ishihara, Y., Fukui-Katoh, K., Morohashi
- Journal Title
  
  Biochem. Biophys. Res. Commun. 341
  
  Pages: 1036-1045
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] 一細胞トランスクリプトーム解析から見えてきた胎仔型ライディッヒ細胞の分化メカニズム2024
- Author(s)
  井上実紀、馬場崇、嶋雄一、諸橋憲一郎
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06395
[Presentation] Nr5a1 遺伝子の下垂体エンハンサー欠損が副腎X-zoneの退縮に及ぼす影響2024
- Author(s)
  渡邊凜乃、井上実紀、嶋香奈子、嶋雄一
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-23K06395
[Presentation] Nr5a1遺伝子の胎生型ライディッヒ細胞エンハンサー欠損の副腎における層構造の形成異常について2024
- Author(s)
  池田裕太、井上実紀、嶋香奈子、嶋雄一
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-23K06395
[Presentation] 脾臓におけるNR5A1/AD4BP/SF-1の機能解析2024
- Author(s)
  嶋（宮林）香奈子、小野公嗣、井上実紀、嶋雄一
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-23K06395
[Presentation] 視床下部-下垂体-生殖腺軸における転写因子NR5A1の機能2023
- Author(s)
  嶋雄一
- Organizer
  日本解剖学会　第79回九州支部学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06395
[Presentation] 脾臓の血管内皮細胞に発現するNR5A1（Ad4BP/SF-1）の機能解明2023
- Author(s)
  嶋雄一
- Organizer
  文部科学省科学研究費補助金新学術領域研究「配偶子インテグリティ」領域会議
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Presentation] ゲノム編集の組織学への応用2023
- Author(s)
  嶋雄一
- Organizer
  第33回電顕サマースクール
- Invited
- Data Source
  KAKENHI-PROJECT-23K06395
[Presentation] Roles of Nuclear Receptor NR5A1 in the Hypothalamic-Pituitary-Gonadal (H-P-G) Ax2023
- Author(s)
  Yuichi Shima
- Organizer
  The 5th International Seminar on Smart Molecule of Natural Resources-Asian Federation of Biotechnology
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06395
[Presentation] 脾臓におけるAD4BP/SF-1/NR5A1陽性内皮細胞の機能的不均一性2022
- Author(s)
  宮林香奈子、小野公嗣、佐藤哲也、Man Ho Choi、Chaelin Lee、嶋雄一
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Presentation] 下垂体ゴナドトロピン産生細胞におけるNR5A1標的遺伝子の探索2022
- Author(s)
  嶋雄一、森天海、宮林香奈子
- Organizer
  第27回日本生殖内分泌学会学術集会
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Presentation] 脾臓の組織構築における核内受容体NR5A1の機能解析2022
- Author(s)
  嶋雄一、宮林香奈子、森天海、佐藤哲也、小野公嗣
- Organizer
  第65回日本顕微鏡学会シンポジウム
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Presentation] 脾洞および辺縁洞内皮細胞の分化を制御する転写カスケードの解明2022
- Author(s)
  森天海、小野公嗣、宮林香奈子、佐藤哲也、樋田一徳、清蔭恵美、嶋雄一
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-21H00235
[Presentation] 精巣ライディッヒ細胞の分化メカニズム解明2021
- Author(s)
  嶋雄一
- Organizer
  第126回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-19K07378
[Presentation] 胎仔ライディッヒ細胞の機能および細胞系譜の解明2021
- Author(s)
  嶋雄一
- Organizer
  第28回日本ステロイドホルモン学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07378
[Presentation] Nr5a1遺伝子下垂体エンハンサー欠損マウスの解析2020
- Author(s)
  嶋雄一
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07378
[Presentation] ゲノム編集により作出したNr5a1遺伝子下垂体エンハンサー欠損マウスの解析2019
- Author(s)
  嶋雄一
- Organizer
  日本アンドロロジー学会第38回学術大会
- Data Source
  KAKENHI-PROJECT-19K07378
[Presentation] 哺乳類における精巣ライディッヒ細胞の分化と男性化のメカニズム2019
- Author(s)
  嶋雄一
- Organizer
  第35回前立腺シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K07378
[Presentation] Elucidation of stage-specific roles of androgens in masculinization of mammals2019
- Author(s)
  嶋雄一
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K07378
[Presentation] 精巣ライディッヒ細胞の分化メカニズムの解明2018
- Author(s)
  嶋　雄一
- Organizer
  第11回日本性差医学・医療学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] 精巣間質細胞の運命決定と遺伝子発現制御2017
- Author(s)
  嶋　雄一
- Organizer
  第35回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] 哺乳類における胎仔型ライディッヒ細胞と成獣型ライディッヒ細胞の分化メカニズム2017
- Author(s)
  嶋　雄一
- Organizer
  日本アンドロロジー学会第36回学術大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] 精巣間質細胞の幹細胞システム2017
- Author(s)
  嶋　雄一
- Organizer
  第22回日本生殖内分泌学会学術集会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] Ad4BP/SF-1遺伝子の発現制御を介したライディッヒ細胞の分化制御機構2017
- Author(s)
  嶋雄一
- Organizer
  第8回転写Clubセミナー
- Place of Presentation
  徳島大学大学院医師薬学研究部　藤井節郎記念医科学センター
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] マウス胎仔期および思春期における男性ホルモン産生細胞の細胞系譜と分化制御2017
- Author(s)
  嶋雄一
- Organizer
  性と生殖の懇談会
- Place of Presentation
  名古屋大学理学部
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] ライディッヒ細胞の脱分化・分化転換による精巣間質の組織構築機構2016
- Author(s)
  嶋雄一
- Organizer
  第184回横浜市立大学医学会講演会　第33回新学術領域「配偶子産生制御」セミナー
- Place of Presentation
  横浜市立大学医学部
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] Ad4BP/SF-1遺伝子の発現制御を介したライディッヒ細胞の脱分化・分化転換2016
- Author(s)
  嶋雄一
- Organizer
  医学研究講義
- Place of Presentation
  鹿児島大学医学部
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01255
[Presentation] 特別講演　Ad4BPレギュロンによる細胞内代謝連関2015
- Author(s)
  諸橋憲一郎、井上実紀、宮林香奈子、宍戸祐里菜、Bing Ki、嶋雄一、馬場崇
- Organizer
  日本アンドロロジー学会第34回学術大会
- Place of Presentation
  福岡市
- Year and Date
  2015-06-26
- Invited
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 胎仔精巣におけるライディッヒ前駆細胞の単離とその分化誘導系の確立2015
- Author(s)
  井上実紀、嶋雄一、宮林香奈子、佐藤哲也、馬場崇、大川恭行、須山幹太、諸橋憲一郎
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸市
- Year and Date
  2015-12-03
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 胎仔型ライディッヒ細胞と成獣型ライディッヒ細胞の細胞系譜の解明2015
- Author(s)
  嶋雄一、宮林香奈子、井上実紀、諸橋憲一郎
- Organizer
  第19回日本生殖内分泌学会学術集会
- Place of Presentation
  千里ライフサイエンスセンタ
- Year and Date
  2015-01-10
- Data Source
  KAKENHI-PROJECT-26670145
[Presentation] 教育講演；Ad4BPによる代謝制御とステロイド合成2015
- Author(s)
  諸橋憲一郎、井上実紀、宮林香奈子、宍戸祐里菜、Bing Li、嶋雄一、馬場崇
- Organizer
  第49回日本小児内分泌学会学術集会
- Place of Presentation
  東京都
- Year and Date
  2015-10-10
- Invited
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] Functional importance of fetal Leydig cells in postnatal testis development2015
- Author(s)
  Shima Y, Miyabayashi K, Suzuki K, Inoue M, Baba T, and Morohashi K
- Organizer
  7th International Symposium on the Biology of Vertebrate Sex Differentiation
- Place of Presentation
  Hawaii, USA
- Year and Date
  2015-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] セルトリ細胞における性染色体構成に依存した遺伝子発現制御機構の解明2014
- Author(s)
  宍戸祐里菜, 馬場崇, 大竹博之, 佐藤哲也, 宮林香奈子, 嶋雄一, 大川恭行, 須山幹太, 諸橋憲一郎
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜市
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 胎仔型ライディッヒ細胞の細胞運命と生理機能の解明2014
- Author(s)
  嶋雄一、宮林香奈子、松﨑佐和子、井上実紀、馬場崇、大竹博之、諸橋憲一郎
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡市
- Year and Date
  2014-04-24
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] Functional characterization of fetal Leydig cells in prenatal and postnatal stages2013
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Kentaro Suzuki, Takashi Baba, Hiroyuki Otake, and Ken-ichirou Morohashi
- Organizer
  SSR (Society for Study of Reproduction)’s 46th annual meeting
- Place of Presentation
  Montreal, Qubec, Canada
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の存在意義2013
- Author(s)
  嶋雄一, 宮林香奈子, 馬場崇, 大竹博之, 諸橋憲一郎
- Organizer
  日本アンドロロジー学会第32回学術大会
- Place of Presentation
  大阪(特別講演)
- Year and Date
  2013-07-25
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の細胞運命と機能2013
- Author(s)
  嶋雄一、宮林香奈子、松崎佐和子、井上実紀、馬場崇、大竹博之、諸橋憲一郎
- Organizer
  第18回日本生殖内分泌学会　学術集会
- Place of Presentation
  東京砂防会館別館（シェーンバッハ・サボー）
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の細胞運命と機能2013
- Author(s)
  嶋雄一, 宮林香奈子, 松崎佐和子, 井上実紀, 馬場崇, 大竹博之, 諸橋憲一郎
- Organizer
  第18回日本生殖内分泌学会学術集会
- Place of Presentation
  東京砂防会館別館(シェーンバッハ・サボー)(口頭発表・学術奨励賞受賞)
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の分化・脱分化に伴う遺伝子発現変化2013
- Author(s)
  嶋雄一、宮林香奈子、松崎佐和子、井上実紀、馬場崇、大竹博之、諸橋憲一郎
- Organizer
  文部科学省科学研究費補助金新学術領域研究「性差構築の分子基盤」第5回領域会議
- Place of Presentation
  国民宿舎　虹の松原ホテル（佐賀県唐津市）
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の分化・脱分化に伴う遺伝子発現変化2013
- Author(s)
  嶋雄一, 宮林香奈子, 松崎佐和子, 井上実紀, 馬場崇, 大竹博之, 諸橋憲一郎
- Organizer
  文部科学省科学研究費補助金新学術領域研究「性差構築の分子基盤」第5回領域会議
- Place of Presentation
  国民宿舎虹の松原ホテル(佐賀県唐津市)(ポスター発表)
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の運命と機能2013
- Author(s)
  嶋雄一
- Organizer
  文部科学省科学研究費補助金新学術領域研究「配偶子幹細胞制御機構」第7回領域会議
- Place of Presentation
  東京海洋大学(公募研究・口頭発表)
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Functional characterization of fetal Leydig cells in prenatal and postnatal stages2013
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Kentaro Suzuki, Takashi Baba, Hiroyuki Otake, and Ken-ichirou Morohashi
- Organizer
  SSR (Society for Study of Reproduction)’s 46th annual meeting
- Place of Presentation
  Montreal, Quebec
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 性差の内分泌制御と遺伝的制御2013
- Author(s)
  嶋雄一、宮林香奈子、大竹博之、馬場崇、諸橋　憲一郎
- Organizer
  フォーラム2013　衛生環境・環境トキシコロジー学会
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 胎仔型ライディッヒ細胞の存在意義2013
- Author(s)
  嶋雄一、宮林香奈子、大竹博之、馬場崇、諸橋　憲一郎
- Organizer
  第32回日本アンドロロジー学会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 胎仔型ライディッヒ細胞における遺伝子発現プロファイルの経時的変化2013
- Author(s)
  宮林香奈子、嶋雄一、佐藤哲也、馬場崇、大竹博之、大川恭行、須山幹太、諸橋憲一郎
- Organizer
  第18回日本生殖内分泌学会学術集会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene2012
- Author(s)
  Yuichi Shima
- Organizer
  Sixth International Symposium on the Biology of Vertebrate Sex Determination
- Place of Presentation
  Hawaii
- Year and Date
  2012-04-23
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] Effect of fetal Leydig cell-specific Ad4BP/SF-1 gene disruption on masculinization and spermatogenesis2012
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Takashi Baba, Hiroyuki Otake, Kentaro Suzuki, Shogo Haraguchi, Kazuyoshi Tsutsui and Ken-ichiroui Morohashi
- Organizer
  The 58th/60th NIBB Conference, Germline #8211;Specification, sex, and stem cells-
- Place of Presentation
  Okazaki, Japan
- Year and Date
  2012-07-17
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] 胎仔精巣におけるテストステロン合成経路の解明2012
- Author(s)
  7. 嶋雄一、宮林香奈子、原口省吾、馬場崇、大竹博之、筒井和義、諸橋憲一郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-14
- Invited
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] Male-specific sex differentiation regulated by fetal Leydig cells2012
- Author(s)
  嶋雄一, 宮林香奈子, 原口省吾, 鈴木堅太郎, 馬場崇, 大竹博之, 筒井和義, 諸橋憲一郎
- Organizer
  第35回日本分子生物学会年会1P-0486
- Place of Presentation
  マリンメッセ福岡(ポスター発表)
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Functional Characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene2012
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Takashi Baba, Hiroyuki Otake, Kentaro Suzuki, Shogo Haraguchi, Kazuyoshi Tsutsui and Ken-ichiroui Morohashi
- Organizer
  Sixth international symposium on vertebrate sex determination
- Place of Presentation
  Kona, Hawaii, USA
- Year and Date
  2012-04-23
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] 胎仔精巣におけるテストステロン合成経路の解明2012
- Author(s)
  嶋雄一, 宮林香奈子, 原口省吾, 馬場崇, 大竹博之, 筒井和義, 諸橋憲一郎
- Organizer
  第85回日本生化学会大会3S02-2(シンポジウム)
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-16
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Effect of fetal Leydig cell-specific Ad4BP/SF-1 gene disruption on masculinization and spermatogenesis2012
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Takashi Baba, Hiroyuki Otake, Kentaro Suzuki, Shogo Haraguchi, Kazuyoshi Tsutsui and Ken-ichiroui Morohashi
- Organizer
  The 58th/60th NIBB Conference, Germline –Specification, sex, and stem cells-
- Place of Presentation
  Okazaki, Japan
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Functional interplay between Leydig and Serotoli cells is essential for testosterone biosynthesis in mouse fetal testis2012
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Takashi Baba, Hiroyuki Otake, Sawako Matsuzaki, Yurina Shishido, Miki Inoue, Shogo Haraguchi, Kazuyoshi Tsutsui and Ken-ichiroui Morohashi
- Organizer
  The 15th International Congress on Hormonal Steroids and Hormones & Cancer
- Place of Presentation
  Kanazawa, Japan
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞によるオス特異的性分化プロセスの内分泌的制御2012
- Author(s)
  嶋雄一, 宮林香奈子, 馬場崇, 大竹博之, 諸橋憲一郎
- Organizer
  文部科学省科学研究費補助金新学術領域研究「性差構築の分子基盤」若手研究会
- Place of Presentation
  和歌山マリーナシティロイヤルパインズホテル(口頭発表)
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Male-specific sex differentiation regulated by fetal Leydig cells2012
- Author(s)
  嶋雄一、宮林香奈子、原口省吾、鈴木堅太郎、馬場崇、大竹博之、筒井和義、諸橋憲一郎
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔精巣におけるテストステロン合成経路の解明ライディッヒ細胞とセルトリ細胞の機能的連携2012
- Author(s)
  嶋雄一, 宮林香奈子, 原口省吾, 馬場崇, 大竹博之, 筒井和義, 諸橋憲一郎
- Organizer
  第17回日本生殖内分泌学会学術集会
- Place of Presentation
  東京ステーションカンファレンス(口頭発表)
- Year and Date
  2012-12-08
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Male-specific sex differentiation regulated by fetal Leydig cells2012
- Author(s)
  16. 嶋雄一、宮林香奈子、原口省吾、鈴木堅太郎、馬場崇、大竹博之、筒井和義、諸橋憲一郎
- Organizer
  第35回日本分子生物学会年会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] 胎仔精巣におけるテストステロン合成経路の解明2012
- Author(s)
  嶋　雄一
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡
- Year and Date
  2012-12-14
- Invited
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] Functional Characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene2012
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Takashi Baba, Hiroyuki Otake, Kentaro Suzuki, Shogo Haraguchi, Kazuyoshi Tsutsui and Ken-ichiroui Morohashi
- Organizer
  Sixth international symposium on vertebrate sex determination
- Place of Presentation
  Kona, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞によるオス特異的性分化プロセスの内分泌的制御2012
- Author(s)
  嶋雄一, 宮林香奈子, 馬場崇, 大竹博之, 諸橋憲一郎
- Organizer
  文部科学省科学研究費補助金新学術領域研究「性差構築の分子基盤」第4回領域会議
- Place of Presentation
  和歌山マリーナシティロイヤルパインズホテル(ポスター発表)
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Functional interplay between Leydig and Serotoli cells is essential for testosterone biosynthesis in mouse fetal testis2012
- Author(s)
  Yuichi Shima, Kanako Miyabayashi, Takashi Baba, Hiroyuki Otake, Sawako Matsuzaki, Yurina Shishido, Miki Inoue, Shogo Haraguchi, Kazuyoshi Tsutsui and Ken-ichiroui Morohashi
- Organizer
  The 15th International Congress on Hormonal Steroids and Hormones Cancer
- Place of Presentation
  Kanazawa, Japan
- Year and Date
  2012-11-15
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] 胎仔精巣におけるテストステロン合成経路の解明　―ライディッヒ細胞とセルトリ細胞の機能的連携―2012
- Author(s)
  嶋雄一、宮林香奈子、原口省吾、馬場崇、大竹博之、筒井和義、諸橋憲一郎
- Organizer
  第17回日本生殖内分泌学会　学術集会
- Place of Presentation
  東京ステーションカンファレンス
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Male-specific sex differentiation regulated by fetal Leydig cells2012
- Author(s)
  嶋雄一, 宮林香奈子, 原口省吾, 鈴木堅太郎, 馬場崇, 大竹博之, 筒井和義, 諸橋憲一郎
- Organizer
  第35回日本分子生物学会年会1W3I-2
- Place of Presentation
  福岡国際会議場(ワークショップ)
- Year and Date
  2012-12-11
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔精巣におけるテストステロン合成経路の解明　―ライディッヒ細胞とセルトリ細胞の機能的連携―2012
- Author(s)
  15. 嶋雄一、宮林香奈子、原口省吾、馬場崇、大竹博之、筒井和義、諸橋憲一郎
- Organizer
  第17回日本生殖内分泌学会　学術集会
- Place of Presentation
  東京ステーションカンファレンス
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] 胎仔精巣におけるテストステロン合成経路の解明2012
- Author(s)
  嶋雄一、宮林香奈子、原口省吾、馬場崇、大竹博之、筒井和義、諸橋憲一郎
- Organizer
  第85回日本生化学会大会
- Place of Presentation
  福岡国際会議場
- Invited
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene (1T5a)2011
- Author(s)
  嶋雄一, 他6名(1番目)
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] 胎仔型ライディッヒ細胞特異的Ad4BP/SF-1遺伝子ノックアウトマウスの解析2011
- Author(s)
  嶋雄一, その他
- Organizer
  第19回日本ステロイドホルモン学会
- Place of Presentation
  福岡
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene2011
- Author(s)
  嶋雄一、宮林香奈子、馬場崇、大竹博之、鈴木堅太郎、山田源、諸橋憲一郎
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の生理学的機能の解明2011
- Author(s)
  嶋雄一、諸橋憲一郎
- Organizer
  第84回日本内分泌学会
- Place of Presentation
  神戸
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 胎仔型ライディッヒ細胞特異的Ad4BP/SF-1遺伝子ノックアウトマウスの解析2011
- Author(s)
  嶋雄一, 他4名(1番目)
- Organizer
  第19回日本ステロイドホルモン学会学術集会
- Place of Presentation
  福岡大学病院メディカルホール
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene (1P-0223)2011
- Author(s)
  嶋雄一, 他6名(1番目)
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] 胎仔型ライディッヒ細胞の生理学的機能の解明2011
- Author(s)
  嶋雄一, 他1名(1番目)
- Organizer
  第84回日本内分泌学会学術集会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PUBLICLY-23116707
[Presentation] Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene2011
- Author(s)
  嶋雄一, 宮林香奈子, 馬場崇, 大竹博之, 鈴木堅太郎
- Organizer
  第34回日本分子生物学会年会1T5a再生・幹細胞・分化
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞の生理学的機能の解明2011
- Author(s)
  嶋雄一, 諸橋憲一郎
- Organizer
  第84回日本内分泌学会学術集会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2011-04-21
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene2011
- Author(s)
  嶋雄一, 宮林香奈子, 馬場崇, 大竹博之, 鈴木堅太郎
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (1P-0223)
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Functional characterization of fetal Leydig cells by cell-specific disruption of Ad4BP/SF-1 gene2011
- Author(s)
  嶋雄一, その他
- Organizer
  第34回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] 胎仔型ライディッヒ細胞による精子形成幹細胞ニッチ形成機構の解明2011
- Author(s)
  嶋雄一, 宮林香奈子, 馬場崇, 大竹博之, 諸橋憲一郎
- Organizer
  文部科学省科学研究費補助金新学術領域研究「配偶子幹細胞制御機構」第5回領域会議
- Place of Presentation
  浜名湖かんざんじ荘(静岡県)(公募研究・口頭発表)
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞特異的Ad4BP/SF-1ノックアウトマウスの解析2011
- Author(s)
  嶋雄一, 宮林香奈子, 馬場崇, 大竹博之, 諸橋憲一郎
- Organizer
  文部科学省科学研究費補助金新学術領域研究「性差構築の分子基盤」第3回領域会議
- Place of Presentation
  国民宿舎虹の松原ホテル(佐賀県)(ポスター発表)
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] 胎仔型ライディッヒ細胞特異的Ad4BP/SF-1遺伝子ノックアウトマウスの解析2011
- Author(s)
  嶋雄一, 馬場崇, 宮林香奈子, 大竹博之, 諸橋憲一郎
- Organizer
  第19回日本ステロイドホルモン学会学術集会
- Place of Presentation
  福岡大学病院メディカルホール
- Year and Date
  2011-11-26
- Data Source
  KAKENHI-PROJECT-23590339
[Presentation] Transcriptomic analysis of fetal Leydig cells2010
- Author(s)
  嶋雄一、宮林香奈子、馬場崇、大竹博之、栗原淑子、諸橋憲一郎
- Organizer
  第33回日本分子生物学会年会ワークショップ「核内受容体研究の最前線」
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] Expression profile of steroidogenic genes in the fetal Leydig cells2010
- Author(s)
  宮林香奈子、嶋雄一、馬場崇、大竹博之、栗原淑子、奥野恭史、諸橋憲一郎
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] Transcriptomic analysis of fetal Leydig cells2010
- Author(s)
  嶋雄一, 他
- Organizer
  第33回日本分子生物学会年会(ワークショップ「核内受容体研究の最前線」)
- Place of Presentation
  神戸ポートピアホテル
- Year and Date
  2010-12-09
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] Transcriptomic analyses of fetal Leydig cell2010
- Author(s)
  Yuichi Shima, Takashi Baba, Kanako Miyabayashi, Hiroyuki Otake, Yoshiko Kurihara, Ken-ichirou Morohashi
- Organizer
  Gordon Research Conference, Reproductive Tract Biology
- Place of Presentation
  Procter Academy, Andover, NH, USA
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] 胎仔型ライディッヒ細胞の生理学的機能の解明2010
- Author(s)
  嶋雄一、馬場崇、宮林香奈子、大竹博之、諸橋憲一郎
- Organizer
  第10回日本内分泌学会九州地方会
- Place of Presentation
  鹿児島大学医学部鶴陵会館
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] Transcriptomic analysis of fetal Leydig cells2010
- Author(s)
  嶋雄一、諸橋憲一郎, 他
- Organizer
  第33回日本分子生物学会、第83回日本生化学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PLANNED-22132002
[Presentation] CELL LINEAGE OF THE FETAL LEYDIG CELL AND ADULT LEYDIG CELL2009
- Author(s)
  Yuichi Shima, Ken-ichirou Morohashi
- Organizer
  Fifth international symposium on the bioiogy of vertebrate sex determination
- Place of Presentation
  Royal Kona Resort Kona, Hawaii, USA
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] Cell lineage of the fetal and adult Leydig cell2009
- Author(s)
  嶋雄一、馬場崇、宮林香奈子、栗原淑子、諸橋憲一郎
- Organizer
  第32 回日本分子生物学会年会
- Place of Presentation
  横浜国際展示場
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] 胎仔型ライディッヒ細胞と成獣型ライディッヒ細胞の細胞系譜の解明2009
- Author(s)
  嶋雄一、諸橋憲一郎
- Organizer
  第17回日本ステロイドホルモン学会
- Place of Presentation
  九州大学医学部百年講堂
- Year and Date
  2009-11-14
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] Cell lineage of the fetal Leydig cell and adult Leydig cell2009
- Author(s)
  嶋雄一、馬場崇、宮林香奈子、栗原淑子、諸橋憲一郎
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜市パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-21790284
[Presentation] Disruption of the aryl hydrocarbon receptor(AhR) induces regression of the seminal vesicle in aged male mice2007
- Author(s)
  T., Baba, Y., Shima, A., Owaki, J., Mimura, M., Oshima, Y., Fujii-Kuriyama, K., Morohashi
- Organizer
  BMB(Biochemistry and Molecular Biology) 2007
- Place of Presentation
  Pacifico Yokohama, Yokohama
- Year and Date
  2007-12-12
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] Ad4BP/SF-1遺伝子の脳下垂体ゴナドトロピン産生細胞特異的エンハンサーの解析2007
- Author(s)
  嶋雄一, 他5名(1番目)
- Organizer
  日本下垂体研究会第22回学術集会
- Place of Presentation
  湘南国際村センター
- Year and Date
  2007-08-25
- Data Source
  KAKENHI-PROJECT-18790644
[Presentation] Identification and characterization of chick sex determination gene2007
- Author(s)
  Y., Ishimaru, H., Yoshioka, M., Kasahara, Y., Katoh-Fukui, K., Morohashi
- Organizer
  BMB(Biochemistry and Molecular Biology)2007
- Place of Presentation
  Pacifico Yokohama, Yokohama
- Year and Date
  2007-12-13
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] Mechanisms of steroidogenic tissue development2006
- Author(s)
  K., Morohashi, M., Zubair, Y., Fukui, Y., Ishimaru, H., Yoshioka
- Organizer
  Symposium on Biological Responses and Inter/Intra Environments
- Place of Presentation
  Fukuoka Recent Hotel, Fukuoka
- Year and Date
  2006-07-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] Function of AhR(Ary1 hydrocarbon receptor) in male and female reproductive tissues2006
- Author(s)
  T., Baba, J., Mimura, Y., Shima, N., Nakamura, N., Harada, M., Yamamoto, K., Morohashi, Y., Fujii-Kuriyama
- Organizer
  Symposium on Biological Responses and Inter/Intra Environments
- Place of Presentation
  Fukuoka Recent Hotel, Fukuoka
- Year and Date
  2006-07-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] Mechanism of asymmetric ovarian development in avian2006
- Author(s)
  Y., Ishimaru, T., Komatsu, M., Kasahara, H., Yoshioka, K., Morohashi
- Organizer
  Symposium on Biological Responses and Inter/Intra Environments
- Place of Presentation
  Fukuoka Recent Hotel, Fukuoka
- Year and Date
  2006-07-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] Genetic program of gonad differentiation2006
- Author(s)
  K., Morohashi, Y., Ishimaru, M., Zubair, S., Oka, K., Miyabayashi, M., Kusaka, Y., Shima, T., Baba, H., Ogawa, H., Yoshioka, Y., Katoh-Fukui
- Organizer
  16th Lake Shirakaba Conference
- Place of Presentation
  St. George's University, Grenada
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] Mechanism for asymmetric gonad development in birds2006
- Author(s)
  H., Yoshioka, Y., Ishimaru, T., Komatsu, M., Kasahara, Y., Katoh-Fukui, K., Morohashi
- Organizer
  International Symposium on "Molecular Mechanisms of Sex Determination and Differentiation" at the 77 thAnnual Meeting of the Zoological Society of Japan
- Place of Presentation
  Shimane Univ. Matsue
- Year and Date
  2006-09-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390091
[Presentation] 胎仔型ライディッヒ細胞の細胞運命と生理機能の解明
- Author(s)
  嶋雄一、宮林香奈子、松崎佐和子、井上実紀、馬場崇、大竹博之、諸橋憲一郎
- Organizer
  第87回日本内分泌学会学術総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2014-04-24 – 2014-04-26
- Data Source
  KAKENHI-PROJECT-26670145

1. MOROHASHI Ken-ichirou (30183114)

# of Collaborated Projects: 2 results

# of Collaborated Products: 29 results
2. BABA Takashi (40435524)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
3. YOKOYAMA Atsushi (20572332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MATSUMOTO Takahiro (70447374)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. MOHAMAD Zubair (70419860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. OHKAWA Yasuyuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 中村桂一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 金井克晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 樋田一徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shima Yuichi 嶋 雄一

SHIMA Yuichi 嶋 雄一

Research Projects

Research Products

Co-Researchers

Elucidation of the physiological significance of mini-puberty based on single-cell analysis of neonatal testisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the importance of mini-puberty on spermatogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular basis of fetal differentiation memory retention in testicular Leydig cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

精子形成を可能とする精巣間質組織の再構築機構とその破綻Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analyses of gene regulatory network in VMH underlying female sexual behaviorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

胎仔型ライディッヒ細胞による精子形成幹細胞ニッチ形成機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of novel biological functions of fetal Leydig cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of sex differences through sex-specific enhancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the mechanisms of the fetal Leydig cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

生殖腺と脳下垂体特異的遺伝子発現調節領域の解析を基盤とする性分化異常症の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of adrenocortical development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Mini-pubertyとオス生殖機能の成熟2023

Author(s)

Journal Title

Data Source

[Journal Article] Tmsb10 triggers fetal Leydig differentiation by suppressing the RAS/ERK pathway.2022

Author(s)

Journal Title

DOI

Data Source

Shima Yuichi 嶋雄一

SHIMA Yuichi 嶋雄一