Motoi Okada 岡田基

… Alternative Names

OKADA Motoi 岡田基

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Researcher Number	80431427
Other IDs	https://orcid.org/0000-0003-3779-6703
Affiliation (Current)	2025: 旭川医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help	2022 – 2025: 旭川医科大学, 医学部, 教授 2015 – 2021: 旭川医科大学, 医学部, 准教授 2010 – 2012: 旭川医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Basic Section 55060:Emergency medicine-related / Emergency medicine / Circulatory organs internal medicine Except Principal Investigator Basic Section 55060:Emergency medicine-related / Circulatory organs internal medicine
Keywords	Principal Investigator 敗血症 / 敗血症性心筋症 / 心筋代謝 / β３受容体 / CLP / 心不全 / ニンジュリン / Fingolimod / S1P / スフィンゴシン1リン酸 … More / メタボリックシフト / LPS / NO産生 / ミトコンドリア / エンドトキシン / カルベジロール / 敗血症性心不全 / テロメア / β遮断薬 / 動脈硬化 / プロスタグランジン / 内皮前駆細胞 / プロスタノイド / 臨床心血管病態学 … More Except Principal Investigator 心不全 / 一酸化窒素 / β3アドレナリン受容体 / 敗血症性心筋症 / 敗血症 / 神経再生 / 動脈硬化 / 末梢神経再生 / 血管安定化 / 血管成熟化 / 血管新生 / 分子血管病態学 Less

Elucidation of the role of Ninj1, a novel inflammation regulatory molecule, in sepsis and its therapeutic ptentialPrincipal Investigator
- Principal Investigator
  
  岡田基
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Asahikawa Medical College
Development of a novel therapeutic strategy for sepsis induced cardiomyopathy through the mechanism of nitric oxide regulation
- Principal Investigator
  
  川口哲
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Asahikawa Medical College
The role of beta-3 receptors and sphingosine 1-phosphate in the regulation of myocardial metabolism in sepsisPrincipal Investigator
- Principal Investigator
  
  Okada Motoi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Asahikawa Medical College
Elucidation of myocardial energy metabolism via beta-3 receptor in sepsisPrincipal Investigator
- Principal Investigator
  
  Okada Motoi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Asahikawa Medical College
Examination about the usefulness and life prognosis factor of the beta blocker in sepsisPrincipal Investigator
- Principal Investigator
  
  Motoi Okada
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  Asahikawa Medical College
Role of prostanoids in the bone marrow derived endothelial cellsPrincipal Investigator
- Principal Investigator
  
  OKADA Motoi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Asahikawa Medical College
Role of neural regenerative factors on vasa vasorum angiogenesis and remodeling of injured vasculature.
- Principal Investigator
  
  KAWABE Junichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Asahikawa Medical College

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2013 2010

All Journal Article Presentation Book

[Book] 心血管系システムとβ３受容体2021
- Author(s)
  岡田　基
- Total Pages
  2
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-18K08879
[Book] 心血管系システムとβ３受容体2021
- Author(s)
  岡田　基
- Total Pages
  2
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-21K09009
[Book] β遮断薬の日米欧ガイドラインにおける位置づけとエビデンス：敗血症2021
- Author(s)
  岡田　基
- Total Pages
  6
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-18K08879
[Book] ショックとβレセプター：β３受容体と敗血症についての考察2019
- Author(s)
  岡田　基
- Total Pages
  8
- Publisher
  総合医学社
- ISBN
  9784883785568
- Data Source
  KAKENHI-PROJECT-18K08879
[Book] 心不全2018
- Author(s)
  岡田　基
- Total Pages
  370
- Publisher
  中山書店
- ISBN
  9784521745831
- Data Source
  KAKENHI-PROJECT-15K10965
[Journal Article] Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy2024
- Author(s)
  Kuroshima Tatsuki、Kawaguchi Satoshi、Okada Motoi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 9 Pages: 4710-4710
- DOI
  10.3390/ijms25094710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09009, KAKENHI-PROJECT-20K17852
[Journal Article] A case of COVID-19-associated fulminant myocarditis successfully treated with mechanical circulatory support2022
- Author(s)
  Ryosuke Asakura 1, Tatsuki Kuroshima 1, Naohiro Kokita 1, Motoi Okada 1
- Journal Title
  
  Clin Case Rep.
  
  Volume: 9 Issue: 9 Pages: 1-6
- DOI
  10.1002/ccr3.6185
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09009
[Journal Article] Cardiac Metabolism in Sepsis2021
- Author(s)
  Kawaguchi Satoshi、Okada Motoi
- Journal Title
  
  Metabolites
  
  Volume: 11 Issue: 12 Pages: 846-846
- DOI
  10.3390/metabo11120846
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08879, KAKENHI-PROJECT-20K17852, KAKENHI-PROJECT-21K09009
[Journal Article] β(3)-Adrenergic receptor blockade reduces mortality in endotoxin-induced heart failure by suppressing induced nitric oxide synthase and saving cardiac metabolism.2020
- Author(s)
  1)Kawaguchi S, Okada M, Ijiri E, Koga D, Watanabe T, Hayashi K, Kashiwagi Y, Fujita S, Hasebe N.
- Journal Title
  
  Am J Physiol Heart Circ Physiol
  
  Volume: 318 Issue: 2 Pages: H283-H294
- DOI
  10.1152/ajpheart.00108.2019
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08093, KAKENHI-PROJECT-18K08879, KAKENHI-PROJECT-19K07261, KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-18K16505, KAKENHI-PROJECT-20K17852
[Journal Article] Prostacyclin stimulated integrin-dependent angiogenic effects of endothelial progenitor cells and mediated potent circulation recovery in ischemic hind limb model2013
- Author(s)
  Aburakawa Y, Kawabe J, Okada M,Yamauchi A, Asanome A, Kabara M,Matsuki M, Takehara N, Nakagawa N,Okumura S, Minami Y, Mizukami Y, YuhkiK, Ushikubi F, Hasebe N
- Journal Title
  
  Circ J
  
  Volume: 77(4) Pages: 1053-1062
- NAID
  10031139011
- Data Source
  KAKENHI-PROJECT-22590765
[Journal Article] Prostacyclin Stimulated Integrin-Dependent Angiogenic Effects of Endothelial Progenitor Cells and Mediated Potent Circulation Recovery in Ischemic Hind Limb Model2013
- Author(s)
  油川陽子、川辺淳一、岡田基　その他
- Journal Title
  
  Circ J
  
  Volume: 77 Issue: 4 Pages: 1053-1062
- DOI
  10.1253/circj.CJ-12-0897
- NAID
  10031139011
- ISSN
  1346-9843, 1347-4820
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590765, KAKENHI-PROJECT-23590294
[Journal Article] Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling2010
- Author(s)
  Kawabe J, Yuhki KI,Okada M, Kanno T, Yamauchi A, Tashiro N,Sasaki T, Okumura S, Nakagawa N,Aburakawa Y, Takehara N, Fujino T, HasebeN, Narumiya S, Ushikubi F
- Journal Title
  
  Atheroscler.Thromb Vasc Biol
  
  Volume: 30 Pages: 464-470
- Data Source
  KAKENHI-PROJECT-22590765
[Presentation] 敗血症での心筋代謝障害のメカニズムと治療戦略2024
- Author(s)
  岡田基
- Organizer
  日本集中治療医学会
- Data Source
  KAKENHI-PROJECT-21K09009
[Presentation] 敗血症性心筋症における心筋ミトコンドリアの構造的・機能的異常と治療戦略2023
- Author(s)
  黒嶋健起、岡田　基
- Organizer
  第50回日本集中治療医学会
- Data Source
  KAKENHI-PROJECT-21K09009
[Presentation] 敗血症性心筋症の治療戦略2023
- Author(s)
  岡田　基
- Organizer
  日本救急医学会
- Data Source
  KAKENHI-PROJECT-21K09009
[Presentation] 敗血症での心機能低下における小胞体―ミトコンドリア機能不全の関与2020
- Author(s)
  岡田　基
- Organizer
  日本救急医学会
- Data Source
  KAKENHI-PROJECT-18K08879
[Presentation] Cardiac Metabolism Was Improved by Regulation of Nitric Oxide Synthases Through the Beta-3 Adrenergic Receptor in Endotoxin-induced Failing Heart2019
- Author(s)
  Okada M
- Organizer
  American Heart Assosiation
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08879
[Presentation] Usefulness of the patch type beta blocker for the rate control of sepsis2017
- Author(s)
  Motoi Okada
- Organizer
  日本集中治療学会
- Data Source
  KAKENHI-PROJECT-15K10965
[Presentation] 侵襲反応を制御する～基礎研究（臨床への架け橋）」敗血症性心筋症でのβ3受容体の役割2017
- Author(s)
  岡田　基
- Organizer
  日本救急医学会
- Data Source
  KAKENHI-PROJECT-15K10965
[Presentation] Carvedilol improved stress cardiomyopathy through the activation of "telomere-p53-PGC signaling2016
- Author(s)
  Motoi Okada
- Organizer
  AHA
- Place of Presentation
  NewOrleans, USA
- Year and Date
  2016-11-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10965
[Presentation] Previous prescription of β-blockers reduced mortality among patients for sepsis2016
- Author(s)
  Motoi Okada
- Organizer
  KSCCM 韓国集中治療学会　日韓合同カンファランス
- Place of Presentation
  韓国　ソウル
- Year and Date
  2016-04-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10965
[Presentation] Carvedilol improves prognosis in sepsis-induced cardiomyopathy through the attenuation of telomere shortening2016
- Author(s)
  Motoi Okada
- Organizer
  ESC ヨーロッパ心臓病学会
- Place of Presentation
  イタリア　ローマ
- Year and Date
  2016-08-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10965
[Presentation] 内皮前駆細胞を介したプロスタサイクリンの下肢虚血改善作用-血管周細胞分化による血管新生効果-2010
- Author(s)
  浅野目晃、川辺淳一、岡田基, 他
- Organizer
  第18回日本血管生物医学会
- Place of Presentation
  大阪、日本
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-22590765

1. 川口哲 (60814217)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
2. KAWABE Junichi (10400087)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
3. 藤田智 (10173428)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. 黒嶋健起 (30898408)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
5. YUHKI Kouiti (80302420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. HIRA Yoshiki (70199024)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAKEHARA Naofumi (90374793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 西浦猛 (90567041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 柏木友太 (70648336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 井尻えり子 (40646072)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 原英樹 (30456892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 長谷部直幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Motoi Okada 岡田 基

OKADA Motoi 岡田 基

Research Projects

Research Products

Co-Researchers

Elucidation of the role of Ninj1, a novel inflammation regulatory molecule, in sepsis and its therapeutic ptentialPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel therapeutic strategy for sepsis induced cardiomyopathy through the mechanism of nitric oxide regulation

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of beta-3 receptors and sphingosine 1-phosphate in the regulation of myocardial metabolism in sepsisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of myocardial energy metabolism via beta-3 receptor in sepsisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination about the usefulness and life prognosis factor of the beta blocker in sepsisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of prostanoids in the bone marrow derived endothelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of neural regenerative factors on vasa vasorum angiogenesis and remodeling of injured vasculature.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 心血管系システムとβ３受容体2021

Author(s)

Total Pages

Publisher

Data Source

[Book] 心血管系システムとβ３受容体2021

Author(s)

Total Pages

Publisher

Data Source

[Book] β遮断薬の日米欧ガイドラインにおける位置づけとエビデンス：敗血症2021

Author(s)

Total Pages

Publisher

Data Source

[Book] ショックとβレセプター：β３受容体と敗血症についての考察2019

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Book] 心不全2018

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A case of COVID-19-associated fulminant myocarditis successfully treated with mechanical circulatory support2022

Motoi Okada 岡田基

OKADA Motoi 岡田基