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Motoi Okada  岡田 基

… Alternative Names

OKADA Motoi  岡田 基

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Researcher Number 80431427
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-3779-6703
Affiliation (Current) 2025: 旭川医科大学, 医学部, 教授
Affiliation (based on the past Project Information) *help 2022 – 2025: 旭川医科大学, 医学部, 教授
2015 – 2021: 旭川医科大学, 医学部, 准教授
2010 – 2012: 旭川医科大学, 医学部, 講師
Review Section/Research Field
Principal Investigator
Basic Section 55060:Emergency medicine-related / Emergency medicine / Circulatory organs internal medicine
Except Principal Investigator
Basic Section 55060:Emergency medicine-related / Circulatory organs internal medicine
Keywords
Principal Investigator
敗血症 / 心筋代謝 / β3受容体 / 敗血症性心筋症 / CLP / 心不全 / Fingolimod / S1P / スフィンゴシン1リン酸 / メタボリックシフト … More / LPS / NO産生 / ミトコンドリア / エンドトキシン / カルベジロール / 敗血症性心不全 / テロメア / β遮断薬 / 動脈硬化 / プロスタグランジン / 内皮前駆細胞 / プロスタノイド / 臨床心血管病態学 … More
Except Principal Investigator
心不全 / 一酸化窒素 / β3アドレナリン 受容体 / 敗血症性心筋症 / 敗血症 / 神経再生 / 動脈硬化 / 末梢神経再生 / 血管安定化 / 血管成熟化 / 血管新生 / 分子血管病態学 Less
  • Research Projects

    (7 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (11 People)
  •  新規の炎症制御分子Ninj1の敗血症における役割の解明と治療への試みPrincipal Investigator

    • Principal Investigator
      岡田 基
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Asahikawa Medical College
  •  Development of a novel therapeutic strategy for sepsis induced cardiomyopathy through the mechanism of nitric oxide regulation

    • Principal Investigator
      川口 哲
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Asahikawa Medical College
  •  The role of beta-3 receptors and sphingosine 1-phosphate in the regulation of myocardial metabolism in sepsisPrincipal Investigator

    • Principal Investigator
      Okada Motoi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Asahikawa Medical College
  •  Elucidation of myocardial energy metabolism via beta-3 receptor in sepsisPrincipal Investigator

    • Principal Investigator
      Okada Motoi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Asahikawa Medical College
  •  Examination about the usefulness and life prognosis factor of the beta blocker in sepsisPrincipal Investigator

    • Principal Investigator
      Motoi Okada
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Emergency medicine
    • Research Institution
      Asahikawa Medical College
  •  Role of prostanoids in the bone marrow derived endothelial cellsPrincipal Investigator

    • Principal Investigator
      OKADA Motoi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Asahikawa Medical College
  •  Role of neural regenerative factors on vasa vasorum angiogenesis and remodeling of injured vasculature.

    • Principal Investigator
      KAWABE Junichi
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Asahikawa Medical College

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2013 2010

All Journal Article Presentation Book

  • [Book] 心血管系システムとβ3受容体2021

    • Author(s)
      岡田 基
    • Total Pages
      2
    • Publisher
      医歯薬出版株式会社
    • Data Source
      KAKENHI-PROJECT-18K08879
  • [Book] 心血管系システムとβ3受容体2021

    • Author(s)
      岡田 基
    • Total Pages
      2
    • Publisher
      医歯薬出版
    • Data Source
      KAKENHI-PROJECT-21K09009
  • [Book] β遮断薬の日米欧ガイドラインにおける位置づけとエビデンス:敗血症2021

    • Author(s)
      岡田 基
    • Total Pages
      6
    • Publisher
      南山堂
    • Data Source
      KAKENHI-PROJECT-18K08879
  • [Book] ショックとβレセプター:β3受容体と敗血症についての考察2019

    • Author(s)
      岡田 基
    • Total Pages
      8
    • Publisher
      総合医学社
    • ISBN
      9784883785568
    • Data Source
      KAKENHI-PROJECT-18K08879
  • [Book] 心不全2018

    • Author(s)
      岡田 基
    • Total Pages
      370
    • Publisher
      中山書店
    • ISBN
      9784521745831
    • Data Source
      KAKENHI-PROJECT-15K10965
  • [Journal Article] Current Perspectives of Mitochondria in Sepsis-Induced Cardiomyopathy2024

    • Author(s)
      Kuroshima Tatsuki、Kawaguchi Satoshi、Okada Motoi
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 9 Pages: 4710-4710

    • DOI

      10.3390/ijms25094710

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09009, KAKENHI-PROJECT-20K17852
  • [Journal Article] A case of COVID-19-associated fulminant myocarditis successfully treated with mechanical circulatory support2022

    • Author(s)
      Ryosuke Asakura 1, Tatsuki Kuroshima 1, Naohiro Kokita 1, Motoi Okada 1
    • Journal Title

      Clin Case Rep.

      Volume: 9 Issue: 9 Pages: 1-6

    • DOI

      10.1002/ccr3.6185

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K09009
  • [Journal Article] Cardiac Metabolism in Sepsis2021

    • Author(s)
      Kawaguchi Satoshi、Okada Motoi
    • Journal Title

      Metabolites

      Volume: 11 Issue: 12 Pages: 846-846

    • DOI

      10.3390/metabo11120846

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08879, KAKENHI-PROJECT-20K17852, KAKENHI-PROJECT-21K09009
  • [Journal Article] β(3)-Adrenergic receptor blockade reduces mortality in endotoxin-induced heart failure by suppressing induced nitric oxide synthase and saving cardiac metabolism.2020

    • Author(s)
      1)Kawaguchi S, Okada M, Ijiri E, Koga D, Watanabe T, Hayashi K, Kashiwagi Y, Fujita S, Hasebe N.
    • Journal Title

      Am J Physiol Heart Circ Physiol

      Volume: 318 Issue: 2 Pages: H283-H294

    • DOI

      10.1152/ajpheart.00108.2019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08093, KAKENHI-PROJECT-18K08879, KAKENHI-PROJECT-19K07261, KAKENHI-PROJECT-16K08458, KAKENHI-PROJECT-18K16505, KAKENHI-PROJECT-20K17852
  • [Journal Article] Prostacyclin stimulated integrin-dependent angiogenic effects of endothelial progenitor cells and mediated potent circulation recovery in ischemic hind limb model2013

    • Author(s)
      Aburakawa Y, Kawabe J, Okada M,Yamauchi A, Asanome A, Kabara M,Matsuki M, Takehara N, Nakagawa N,Okumura S, Minami Y, Mizukami Y, YuhkiK, Ushikubi F, Hasebe N
    • Journal Title

      Circ J

      Volume: 77(4) Pages: 1053-1062

    • NAID

      10031139011

    • Data Source
      KAKENHI-PROJECT-22590765
  • [Journal Article] Prostacyclin Stimulated Integrin-Dependent Angiogenic Effects of Endothelial Progenitor Cells and Mediated Potent Circulation Recovery in Ischemic Hind Limb Model2013

    • Author(s)
      油川陽子、川辺淳一、岡田基 その他
    • Journal Title

      Circ J

      Volume: 77 Issue: 4 Pages: 1053-1062

    • DOI

      10.1253/circj.CJ-12-0897

    • NAID

      10031139011

    • ISSN
      1346-9843, 1347-4820
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22590765, KAKENHI-PROJECT-23590294
  • [Journal Article] Prostaglandin I2 promotes recruitment of endothelial progenitor cells and limits vascular remodeling2010

    • Author(s)
      Kawabe J, Yuhki KI,Okada M, Kanno T, Yamauchi A, Tashiro N,Sasaki T, Okumura S, Nakagawa N,Aburakawa Y, Takehara N, Fujino T, HasebeN, Narumiya S, Ushikubi F
    • Journal Title

      Atheroscler.Thromb Vasc Biol

      Volume: 30 Pages: 464-470

    • Data Source
      KAKENHI-PROJECT-22590765
  • [Presentation] 敗血症での心筋代謝障害のメカニズムと治療戦略2024

    • Author(s)
      岡田基
    • Organizer
      日本集中治療医学会
    • Data Source
      KAKENHI-PROJECT-21K09009
  • [Presentation] 敗血症性心筋症における心筋ミトコンドリアの構造的・機能的異常と治療戦略2023

    • Author(s)
      黒嶋健起、岡田 基
    • Organizer
      第50回日本集中治療医学会
    • Data Source
      KAKENHI-PROJECT-21K09009
  • [Presentation] 敗血症性心筋症の治療戦略2023

    • Author(s)
      岡田 基
    • Organizer
      日本救急医学会
    • Data Source
      KAKENHI-PROJECT-21K09009
  • [Presentation] 敗血症での心機能低下における小胞体―ミトコンドリア機能不全の関与2020

    • Author(s)
      岡田 基
    • Organizer
      日本救急医学会
    • Data Source
      KAKENHI-PROJECT-18K08879
  • [Presentation] Cardiac Metabolism Was Improved by Regulation of Nitric Oxide Synthases Through the Beta-3 Adrenergic Receptor in Endotoxin-induced Failing Heart2019

    • Author(s)
      Okada M
    • Organizer
      American Heart Assosiation
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K08879
  • [Presentation] Usefulness of the patch type beta blocker for the rate control of sepsis2017

    • Author(s)
      Motoi Okada
    • Organizer
      日本集中治療学会
    • Data Source
      KAKENHI-PROJECT-15K10965
  • [Presentation] 侵襲反応を制御する~基礎研究(臨床への架け橋)」敗血症性心筋症でのβ3受容体の役割2017

    • Author(s)
      岡田 基
    • Organizer
      日本救急医学会
    • Data Source
      KAKENHI-PROJECT-15K10965
  • [Presentation] Carvedilol improved stress cardiomyopathy through the activation of "telomere-p53-PGC signaling2016

    • Author(s)
      Motoi Okada
    • Organizer
      AHA
    • Place of Presentation
      NewOrleans, USA
    • Year and Date
      2016-11-14
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10965
  • [Presentation] Previous prescription of β-blockers reduced mortality among patients for sepsis2016

    • Author(s)
      Motoi Okada
    • Organizer
      KSCCM 韓国集中治療学会 日韓合同カンファランス
    • Place of Presentation
      韓国 ソウル
    • Year and Date
      2016-04-23
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10965
  • [Presentation] Carvedilol improves prognosis in sepsis-induced cardiomyopathy through the attenuation of telomere shortening2016

    • Author(s)
      Motoi Okada
    • Organizer
      ESC ヨーロッパ心臓病学会
    • Place of Presentation
      イタリア ローマ
    • Year and Date
      2016-08-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10965
  • [Presentation] 内皮前駆細胞を介したプロスタサイクリンの下肢虚血改善作用-血管周細胞分化による血管新生効果-2010

    • Author(s)
      浅野目晃、川辺淳一、岡田基, 他
    • Organizer
      第18回日本血管生物医学会
    • Place of Presentation
      大阪、日本
    • Year and Date
      2010-12-02
    • Data Source
      KAKENHI-PROJECT-22590765
  • 1.  藤田 智 (10173428)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  川口 哲 (60814217)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  KAWABE Junichi (10400087)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 4.  黒嶋 健起 (30898408)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 5.  YUHKI Kouiti (80302420)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  HIRA Yoshiki (70199024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  TAKEHARA Naofumi (90374793)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  西浦 猛 (90567041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  柏木 友太 (70648336)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  井尻 えり子 (40646072)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  長谷部 直幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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