Isaji Tomoya 伊左治知弥

… Alternative Names

ISAJI Tomoya 伊左治知弥

伊佐治知弥イサジトモヤ

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Researcher Number	80433514
Other IDs
Affiliation (Current)	2025: 東北医科薬科大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 東北医科薬科大学, 薬学部, 准教授 2019 – 2021: 東北医科薬科大学, 薬学部, 講師 2016: 東北医科薬科大学, 薬学部, 講師 2008 – 2015: Tohoku Pharmaceutical University, 薬学部, 助教 2007: Tohoku Pharmaceutical University, 薬学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Functional biochemistry / Biological pharmacy Except Principal Investigator Basic Section 43030:Functional biochemistry-related / Respiratory organ internal medicine / Functional biochemistry
Keywords	Principal Investigator インテグリン / 糖鎖 / がん / 細胞接着 / N-型糖鎖 / シアル酸 / 接着 / Focal adhesion kinase / シアリル化 / ユビキチン化 … More / GOLPH3 / シアリルトランスフェラーゼ / PI4P / シア酸 / PI4KIIα / 転移 / PI4K / 複合体形成 / 超分子複合体 / 細胞増殖 / 癌 … More Except Principal Investigator 糖鎖 / インテグリン / 糖転移酵素 / GnT-III / 細胞接着 / 膜受容体 / がん薬剤耐性 / GnTーIII / 薬剤耐性 / N型糖鎖 / シグナル伝達 / シグナル / UDP-GlcNAc輸送体 / N-型糖鎖 / O-GlcNAc / 細胞接着分子 / 遺伝子 / アレルギー・ぜんそく / 免疫学 / 遺伝子多型 / オピオイド受容体 / ストレス / 喘息 / カデニン / カドヘリン / GnT-V / TGF-β / 細胞移動 / E-カドヘリン / 細胞間接着 / EMT / N-結合型糖鎖 / 細胞接着因子 / E-cadherin / integrin / cell adhesion / N-glycosylation Less

シアリル化N-型糖鎖修飾の特異性とその制御機構Principal Investigator
- Principal Investigator
  
  伊左治知弥
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Analysis of underlying molecular mechanism for the regulation of chemoresistance by GnT-III
- Principal Investigator
  
  顧建国
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Regulatory mechanism of sialylation of N-glycans by focal adhesion kinase (FAK) and its biological significancePrincipal Investigator
- Principal Investigator
  
  伊左治知弥
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Regulation and significance of new sialylated glycan biosynthesis via integrin alpha3Principal Investigator
- Principal Investigator
  
  Isaji Tomoya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Functions of glycosylation in integrin-mediated outside-in and inside-out signaling
- Principal Investigator
  
  Gu Jianguo
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tohoku Medical and Pharmaceutical University
Role of functional single-nucleotide polymorphism of the opioid receptor gene in stress-induced exacerbation of asthma
- Principal Investigator
  
  OHNO Isao
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Respiratory organ internal medicine
- Research Institution
  Tohoku Medical and Pharmaceutical University
Functional analysis of N-glycan on integrin alpha5beta1 for supramolecular assembly and cell proliferationPrincipal Investigator
- Principal Investigator
  
  ISAJI Tomoya
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku Pharmaceutical University
インテグリンα5β1を介した超分子複合体の特異性とその意義Principal Investigator
- Principal Investigator
  
  伊左治知弥
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku Pharmaceutical University
Change of oligosaccharides in cell adhesion, and its roles
- Principal Investigator
  
  GU Jianguo
- Project Period (FY)
  2009 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  Tohoku Pharmaceutical University
Identification of functional module of N-glycans on α5β1 integrinPrincipal Investigator
- Principal Investigator
  
  ISAJI Tomoya
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Tohoku Pharmaceutical University

[Book] インテグリンのN-結合型糖鎖による細胞接着機能の調節2008
- Author(s)
  顧建国、伊左治知弥
- Publisher
  蛋白質核酸酵素(共立出版)
- Data Source
  KAKENHI-PROJECT-19790068
[Book] 細胞接着2007
- Author(s)
  佐藤裕也、伊左治知弥、顧建国
- Publisher
  The Lung perspectives. (メディカルレビュー社)
- Data Source
  KAKENHI-PROJECT-19790068
[Book] 細胞移動2007
- Author(s)
  伊左治知弥、佐藤裕也、顧建国
- Publisher
  The Lung perspectives. (メディカルレビュー社)
- Data Source
  KAKENHI-PROJECT-19790068
[Journal Article] Exogenous l-fucose attenuates neuroinflammation induced by lipopolysaccharide2024
- Author(s)
  Xu Xing、Fukuda Tomohiko、Takai Jun、Morii Sayaka、Sun Yuhan、Liu Jianwei、Ohno Shiho、Isaji Tomoya、Yamaguchi Yoshiki、Nakano Miyako、Moriguchi Takashi、Gu Jianguo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 300 Issue: 1 Pages: 105513-105513
- DOI
  10.1016/j.jbc.2023.105513
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19443, KAKENHI-PROJECT-22K06615, KAKENHI-PROJECT-22K06913, KAKENHI-PROJECT-21K06547, KAKENHI-PROJECT-23K27133
[Journal Article] BRCC36 associates with FLT3‐ITD to regulate its protein stability and intracellular signaling in acute myeloid leukemia2024
- Author(s)
  Liu Jianwei、Isaji Tomoya、Komatsu Sachiko、Sun Yuhan、Xu Xing、Fukuda Tomohiko、Fujimura Tsutomu、Takahashi Shinichiro、Gu Jianguo
- Journal Title
  
  Cancer Science
  
  Volume: 115 Issue: 4 Pages: 1196-1208
- DOI
  10.1111/cas.16090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19443, KAKENHI-PROJECT-21K07346, KAKENHI-PROJECT-22K06615, KAKENHI-PROJECT-23K27133
[Journal Article] Expression of GnT-III decreases chemoresistance via negatively regulating P-glycoprotein expression: Involvement of the TNFR2-NF-κB signaling pathway2023
- Author(s)
  Song Wanli、Liang Caixia、Sun Yuhan、Morii Sayaka、Yomogida Shin、Isaji Tomoya、Fukuda Tomohiko、Hang Qinglei、Hara Akiyoshi、Nakano Miyako、Gu Jianguo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 4 Pages: 103051-103051
- DOI
  10.1016/j.jbc.2023.103051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06547, KAKENHI-PROJECT-22K06615, KAKENHI-PROJECT-22K19443, KAKENHI-PROJECT-19H03184, KAKENHI-PROJECT-23K27133
[Journal Article] Focal-adhesion kinase regulates the sialylation of N-glycans via the PI4KIIα-PI4P pathway2023
- Author(s)
  Sun Yuhan、Isaji Tomoya、Oyama Yoshiyuki、Xu Xing、Liu Jianwei、Hanamatsu Hisatoshi、Yokota Ikuko、Miura Nobuaki、Furukawa Jun-ichi、Fukuda Tomohiko、Gu Jianguo
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 299 Issue: 8 Pages: 105051-105051
- DOI
  10.1016/j.jbc.2023.105051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19443, KAKENHI-PROJECT-22K06615, KAKENHI-PROJECT-23K24759, KAKENHI-PROJECT-23K27133
[Journal Article] O-GlcNAcylation Regulates β1,4-GlcNAc-branched N-glycan Biosynthesis Via the OGT/SLC35A3/GnT-IV Axis.2022
- Author(s)
  Song, W., Isaji, T., Nakano, M., Liang C., Fukuda, T.and Gu, J.
- Journal Title
  
  FASEB J.
  
  Volume: 36 Issue: 2 Pages: 210-210
- DOI
  10.1096/fj.202101520r
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04909, KAKENHI-PROJECT-19H02922, KAKENHI-PROJECT-19H03184, KAKENHI-WRAPUP-22H04899
[Journal Article] α1,6-Fucosyltransferase contributes to cell migration and proliferation as well as to cancer stemness features in pancreatic carcinoma.2021
- Author(s)
  Caixia Liang, Tomohiko Fukuda, Tomoya Isaji, Chengwei Duan, Wanli Song, Yuqin Wang, Jianguo Gu
- Journal Title
  
  Biochimica et biophysica acta. General subjects
  
  Volume: 1865 Issue: 6 Pages: 129870-129870
- DOI
  10.1016/j.bbagen.2021.129870
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H04909, KAKENHI-PROJECT-19H03184, KAKENHI-PROJECT-19K07049
[Journal Article] Deficiency of core fucosylation activates cellular signaling dependent on FLT3 expression in a Ba/F3 cell system2020
- Author(s)
  Duan Chengwei、Fukuda Tomohiko、Isaji Tomoya、Qi Feng、Yang Jie、Wang Yuqin、Takahashi Shinichiro、Gu Jianguo
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 2 Pages: 3239-3252
- DOI
  10.1096/fj.201902313rr
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07049, KAKENHI-PUBLICLY-18H04868, KAKENHI-PROJECT-19H03184, KAKENHI-PROJECT-17K09019
[Journal Article] Identification of the minimal N-glycosylation on integrin α5β1 required for its inhibitory effect on EGFR signaling and cell proliferation2020
- Author(s)
  Hou Sicong、Hang Qinglei、Isaji Tomoya、Fukuda Tomohiko、Gu Jianguo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 523 Issue: 1 Pages: 226-232
- DOI
  10.1016/j.bbrc.2019.11.188
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07049, KAKENHI-PUBLICLY-18H04868, KAKENHI-PROJECT-19H03184
[Journal Article] EpCAM associates with integrin and regulates cell adhesion in cancer cells2020
- Author(s)
  Yang Jie、Isaji Tomoya、Zhang Guowei、Qi Feng、Duan Chengwei、Fukuda Tomohiko、Gu Jianguo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 522 Issue: 4 Pages: 903-909
- DOI
  10.1016/j.bbrc.2019.11.152
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07049, KAKENHI-PUBLICLY-18H04868, KAKENHI-PROJECT-19H03184
[Journal Article] ST3GAL3, ST3GAL4, and ST3GAL6 differ in their regulation of biological functions via the specificities for the α2,3‐sialylation of target proteins2020
- Author(s)
  Qi Feng、Isaji Tomoya、Duan Chengwei、Yang Jie、Wang Yuqin、Fukuda Tomohiko、Gu Jianguo
- Journal Title
  
  The FASEB Journal
  
  Volume: 34 Issue: 1 Pages: 881-897
- DOI
  10.1096/fj.201901793r
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07049, KAKENHI-PUBLICLY-18H04868, KAKENHI-PROJECT-19H03184
[Journal Article] Importance of membrane-proximal N-glycosylation on integrin β1 in its activation and complex formation.2016
- Author(s)
  Hou S, Hang Q, Isaji T, Lu J, Fukuda T, Gu J
- Journal Title
  
  FASEB J
  
  Volume: 30 Pages: 4120-4131
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461164
[Journal Article] N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4.2016
- Author(s)
  Hang, Q., Isaji, T., Hou, S., Zhou, Y., Fukuda, T. and Gu, J.
- Journal Title
  
  Sci. Rep.
  
  Volume: 10 Issue: 1 Pages: 1-15
- DOI
  10.1038/srep33507
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04354, KAKENHI-PROJECT-25461164, KAKENHI-PROJECT-15K14408
[Journal Article] Transforming growth factor (TGF) β1 acted through miR-130b to increase integrin α5 to promote migration of colorectal cancer cells.2016
- Author(s)
  Yi R., Li Y., Wang F., Gu J., Isaji T., Li J., Qi R., Zhu X. and Zhao Y.
- Journal Title
  
  Tumour Biol.
  
  Volume: 37 Issue: 8 Pages: 10763-73
- DOI
  10.1007/s13277-016-4965-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04354, KAKENHI-PROJECT-25461164, KAKENHI-PROJECT-15K14408
[Journal Article] Integrin α5 Suppresses the Phosphorylation of Epidermal Growth Factor Receptor and Its Cellular Signaling of Cell Proliferation via N-Glycosylation2015
- Author(s)
  Hang Q, Isaji T, Hou S, Im S, Fukuda T, Gu J.
- Journal Title
  
  J Biol Chem
  
  Volume: 290 Issue: 49 Pages: 29345-60
- DOI
  10.1074/jbc.m115.682229
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461164, KAKENHI-PROJECT-15K14408, KAKENHI-PROJECT-15H04354
[Journal Article] MicroRNA 130b suppresses migration and invasion of colorectal cancer cells through downregulation of integrin.2014
- Author(s)
  Zhao, Y., Miao, G., Li, Y., Isaji, T., Gu, J., Li, J., Qi, R.
- Journal Title
  
  PLoS One
  
  Volume: 9 Issue: 2 Pages: e87938-e87938
- DOI
  10.1371/journal.pone.0087938
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21370059, KAKENHI-PROJECT-24570169
[Journal Article] b-Galactoside a2,6 Sialyltranferase 1 Is Required for the Sufficient Induction of Transforming Growth Factor-b1-Mediated Epithelial-Mesenchymal Transition2014
- Author(s)
  Lu J, Isaji T, Im S, Fukuda T, Hashii N, Takakura D, Kawasaki N, Gu J
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 289 Issue: 50 Pages: 34627-34641
- DOI
  10.1074/jbc.m114.593392
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23110006, KAKENHI-PROJECT-24570169
[Journal Article] An oncogenic protein Golgi phosphoprotein 3 up-regulates cell migration via sialylation2014
- Author(s)
  Isaji, T., Im, S., Gu, W., Wang, Y., Hang, H., Lu, J., Fukuda, T., Hashii, N., Takakura, D., Kawasaki, N., Miyoshi, H. and Gu, J.
- Journal Title
  
  J Biol. Chem
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] An oncogenic protein Golgi phosphoprotein 3 up-regulates cell migration via sialylation.2014
- Author(s)
  Isaji T, Im S, Gu W, Wang Y, Hang Q, Lu J, Fukuda T, Hashii N, Takakura D, Kawasaki N, Miyoshi H, Gu J.
- Journal Title
  
  J Biol Chem
  
  Volume: 289 Pages: 20694-20705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461164
[Journal Article] An Oncogenic Protein Golgi Phosphoprotein 3 up-regulates Cell Migration via Sialylation.2014
- Author(s)
  Isaji T, Im S, Gu W, Wang Y, Hang Q, Lu J, Fukuda T, Hashii N, Takakura D, Kawasaki N, Miyoshi H, Chin L, Gu J
- Journal Title
  
  J.Biol. Chem.
  
  Volume: 289 Issue: 30 Pages: 20694-20705
- DOI
  10.1074/jbc.m113.542688
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23110006, KAKENHI-PROJECT-24570169
[Journal Article] α1,6-Fucosylation regulates neurite formation via the activin/phospho-Smad2 pathway in PC12 cells: the implicated dual effects of Fut8 for TGF-β/activin-mediated signaling.2013
- Author(s)
  Gu, W., Fukuda, T., Isaji, T., Hashimoto, H., Wang., Y and Gu, J.
- Journal Title
  
  FASEB J
  
  Volume: 27 Issue: 10 Pages: 3947-3958
- DOI
  10.1096/fj.12-225805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370059, KAKENHI-PROJECT-23651196, KAKENHI-PUBLICLY-24110513, KAKENHI-PROJECT-24570169, KAKENHI-PROJECT-24590087
[Journal Article] α1, 6-Fucosylation regulates neurite formation via the activin/phospho-Smad2 pathway in PC12 cells : the implicated dual effects of Fut8 for TGF-β/activin-mediated signaling2013
- Author(s)
  Gu, W., Fukuda, T., Isaji, T., Hashimoto, H., Wang., Y and Gu, J.
- Journal Title
  
  FASEB J
  
  Volume: 27 Pages: 3947-3958
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] E-cadherin and adherens-junctions stability in gastric carcinoma: Functional implications of glycosyltransferases involving N-glycan branching biosynthesis, N-acetylglucosaminyltransferases III and V.2013
- Author(s)
  Pinho, SS., Figueiredo, J., Cabral, J., Carvalho, S., Dourado, J., Gärtner, F., Mendonça, AM., Isaji, T., Gu, J., Carneiro, F., Seruca, R., Taniguchi, N., Reis, CA.
- Journal Title
  
  Biochim. Biophys. Acta
  
  Volume: 1830 Pages: 2690-2700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] Anti-tumor effects of exogenous ganglioside GM3 on bladder cancer in an orthotopic cancer model.2013
- Author(s)
  Wang, H., et al
- Journal Title
  
  Urology
  
  Volume: 81 Issue: 1 Pages: 210-210
- DOI
  10.1016/j.urology.2012.08.015
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370059, KAKENHI-PROJECT-23651196, KAKENHI-PROJECT-24570169
[Journal Article] Potential roles of N-glycosylation in cell adhesion.2012
- Author(s)
  Gu, J., et al
- Journal Title
  
  Glycoconj J
  
  Volume: 29 Issue: 8-9 Pages: 599-607
- DOI
  10.1007/s10719-012-9386-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370059, KAKENHI-PROJECT-23651196, KAKENHI-PROJECT-23790373, KAKENHI-PROJECT-24570169, KAKENHI-PROJECT-24590087, KAKENHI-PUBLICLY-24110513
[Journal Article] Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by TGF-β1 in epithelial cell lines2012
- Author(s)
  Xu, Q., Isaji, T., Lu, Y., Gu, W., Kondo, M., Fukuda, T., Du, Y. and Gu, J.
- Journal Title
  
  J Biol Chem
  
  Volume: 287 Pages: 16563-74
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] α1, 6-Fucosyltransferase-deficient mice exhibit multiple behavioral abnormalities associated with a schizophrenia-like phenotype : importance of the balance between the dopamine and serotonin systems2011
- Author(s)
  Fukuda, T., Hashimoto, H., Okayasu, N., Kameyama, A., Onogi, H., Nakagawasai, O, Nakazawa, T., Kurosawa, T., Hao, Y., Isaji, T., Tadano, T., Narimatsu, H., Taniguchi, N. and Gu, J.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 18434-43
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] Wnt/β-catenin Signaling Down-regulates N-Acetylglucosaminyltransferase III Expression : The implication of two mutually exclusive pathways for regulation2011
- Author(s)
  Xu, Q., Akama, R., Isaji, T., Lu, Y., Hashimoto, H., Kariya, Y., Fukuda, T., Du Y., Gu, J.
- Journal Title
  
  J Biol Chem
  
  Volume: 286(6) Issue: 6 Pages: 4310-4318
- DOI
  10.1074/jbc.m110.182576
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22770130
[Journal Article] Wnt/β-catenin Signaling Down-regulates N-Acetylglucosaminyltransferase III Expression : The implication of two mutually exclusive pathways for regulation2011
- Author(s)
  Xu, Q., Akama, R., Isaji, T., Lu, Y., Hashimoto, H., Kariya, Y., Fukuda, T., Du, Y., and Gu, J.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 286 Pages: 4310-8
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] alpha 1,6-Fucosyltransferase-deficient Mice Exhibit Multiple Behavioral Abnormalities Associated with a Schizophrenia-like Phenotype2011
- Author(s)
  Tomohiko Fukuda, Hirokazu Hashimoto, Natsumi Okayasu, Akihiko Kameyama, Hiroshi Onogi, Osamu Nakagawasai, Takahiro Nakazawa, Tomoyo Kurosawa, Yan Hao, Tomoya Isaji, Takeshi Tadano, Hisashi Narimatsu
- Journal Title
  
  THE JOURNAL OF BIOLOGICAL CHEMISTRY
  
  Volume: 286 Issue: 21 Pages: 18434-18443
- DOI
  10.1074/jbc.m110.172536
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590071, KAKENHI-PROJECT-22770130
[Journal Article] Functional roles of the bisecting GlcNAc in integrin-mediated cell adhesion.2010
- Author(s)
  Isaji, T., et al.
- Journal Title
  
  Methods Enzymol.
  
  Volume: 480 Pages: 445-459
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] N-glycosylation of the I-like domain of betal integrin is essential for betal interin expression and biological function : Identification of the minimal N-glycosylation requirement for alpha 5beta 12009
- Author(s)
  Isaji, T., et al.
- Journal Title
  
  J.Biol.Chem. 284
  
  Pages: 12207-12216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1, 4-N-acetylglucosaminyltransferase III.2009
- Author(s)
  Sato, Y., Isaji, T., Tajiri, M., Yoshida-Yamamoto, S., Yoshinaka, T., Somehara, T., Fukuda, T., Wada, Y. and Gu, J.
- Journal Title
  
  J. Biol. Chem. 284
  
  Pages: 11873-1188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790068
[Journal Article] N-glycosylation of the I-like domain of β1 integrin is essential for β1 in tegrin expression and biological function2009
- Author(s)
  Tomoya Isaji
- Journal Title
  
  The Journal of Biological Chemistry (In press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790068
[Journal Article] An N-glycosylation site on the beta-propeller domain of the integrin alpha5 subunit plays key roles in both its function and site-specific modification by beta1, 4-N-acetylglucosaminyltransferase III2009
- Author(s)
  Sato, Y., Isaji, T., Tajiri, M., Yoshida-Yamamoto, S., Yoshinaka, T., Somehara, T., Fukuda, T., Wada, Y. and Gu, J.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 284 Pages: 11873-81
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] N-glycosylation of the I-like domain of beta1 integrin is essential for beta1 integrin expression and biological function : Identification of the minimal N-glycosylation requirement for alpha 5beta 12009
- Author(s)
  Isaji, T., Sato, Y., Fukuda, T. and Gu, J.
- Journal Title
  
  J. Biol. Chem
  
  Volume: 284 Pages: 12207-16
- Data Source
  KAKENHI-PROJECT-21370059
[Journal Article] N-glyc osylation of the I-like domain of beta 1 integrin is essential for beta 1 integrin expression and biological function2009
- Author(s)
  Isaji, T., Sato, Y., Fukuda, T. and Gu, J
- Journal Title
  
  J. Biol. Chem 284
  
  Pages: 12207-12216
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790068
[Journal Article] Biochemical visualization of cell surface molecular clustering in living cells.2008
- Author(s)
  Kotani, N., Gu, J., Isaji, T., Udaka, K., Taniguchi, N., and Honke, K.
- Journal Title
  
  Proc. Natl. Acad. Sci. 105
  
  Pages: 7405-7409
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790068
[Journal Article] N-Acetylglucosaminyltransferase III Expression Is Regulated by Cell-Cell Adhesion via the E-cadherin-catenin-actin Complex.2008
- Author(s)
  Akama, R., Sato, Y., Kariya, Y., Isaji, T., Fukuda, T., Lu, L., Taniguchi, N., Ozawa, M. and Gu, J.
- Journal Title
  
  PROTEOMICS. 8
  
  Pages: 3321-3328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790068
[Presentation] L-fucose投与によるLPS誘発性脳内炎症抑制とその機序2024
- Author(s)
  福田友彦, 徐興, 高井淳, 伊左治知弥, 山口芳樹, 中ノ三弥子, 森口尚, 顧建国
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K27133
[Presentation] 脱ユビキチン酵素BRCC36を標的とした急性骨髄性白血病治療の可能性2024
- Author(s)
  伊左治知弥, 劉建偉, 小松祥子, 福田友彦,藤村務, 高橋伸一郎, 顧建国
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K27133
[Presentation] The expression of GnT-III decreases chemoresistance via negatively　regulating P-glycoprotein expression in K562 cells2023
- Author(s)
  孫鈺涵，伊左治知弥，福田友彦，顧建国
- Organizer
  日本生化学会東北支部第89回例会
- Data Source
  KAKENHI-PROJECT-23K27133
[Presentation] RCC36 を標的とした急性骨髄性白血病治療の可能性2023
- Author(s)
  伊左治知弥，劉健偉，段程偉，小松祥子，福田友彦，藤村務，髙橋伸一郎，顧建国
- Organizer
  第６２回日本薬学会東北支部大会
- Data Source
  KAKENHI-PROJECT-22K06615
[Presentation] がん薬剤耐性におけるN型糖鎖の変化とその意義2023
- Author(s)
  宋万里、梁彩霞、孫鈺涵、森井彩、蓬田伸、伊左治知弥、福田友彦、原明義、中の三弥子, 顧　建国
- Organizer
  日本薬学会第１４３年会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] Focal adhesion kinaseを介する新規なシアリル化N-型糖鎖の調節機構2023
- Author(s)
  伊左治知弥, 孫鈺涵, 大山嘉順, 徐興, 劉健偉, 福田友彦, 顧建国
- Organizer
  日本生化学会東北支部第89回例会
- Data Source
  KAKENHI-PROJECT-22K06615
[Presentation] ・BRCC36とFLT3-ITDの相互作用による蛋白質の安定性と細胞内シグナルへの影響2023
- Author(s)
  伊左治知弥，劉健偉，段程偉，小松祥子，福田友彦，藤村務，髙橋伸一郎，顧建国
- Organizer
  第42回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-22K06615
[Presentation] Alteration in N‐Glycans in Cancer Drug Resistance2023
- Author(s)
  Jianguo Gu, Tomoya Isaji and Tomohiko Fukuda
- Organizer
  International symposium on glycoconjugates (Glyco26)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27133
[Presentation] A novel molecular mechanism for sialylation regulated through the integrin-FAK-PI4K-GOLPH3-sialytransferase axis2022
- Author(s)
  Yuhan Sun, Tomoya Isaji, Tomohiko Fukuda and Jianguo Gu
- Organizer
  The 29th FAOBMB & 2022 CSBMB
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] インテグリン-FAK-PI4K軸を介したN-型糖鎖のシアリル化制御2022
- Author(s)
  伊左治　知弥、孫　鈺涵、福田　友彦、顧　建国
- Organizer
  第41回日本糖質学会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] 接着斑キナーゼはPI4KIIα-PI4P経路を介してシアリル化N-型糖鎖を制御する2022
- Author(s)
  伊左治　知弥、孫　鈺涵、福田　友彦、顧　建国
- Organizer
  第95回日本生化学会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] 糖ヌクレオチド輸送体（SLC35 ファミリー）を介した O-GlcNAc 修飾と N-型糖鎖生合成の関連性について2022
- Author(s)
  関川諒, 宋万里, 伊左治知弥, 福田友彦, 顧建国
- Organizer
  第16回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] UDP-GlcNAc を共通ドナー基質とする O-GlcNAc、ヒアルロン酸と N型糖鎖間の相互作用に関して2022
- Author(s)
  小野拓朗, 黒田喜幸, 伊左治知弥, 福田友彦, 顧建国
- Organizer
  第16回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] OGTはOGT/SLC35A3/GnT-IV軸を介してβ1,4-GlcNAc分岐型 N型糖鎖の生合成を制御する2022
- Author(s)
  宋万里, 伊左治知弥, 中の三弥子, 福田友彦, 顧建国
- Organizer
  第16回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] A novel regulatory mechanism for sialylation via the integrin-FAK-PI4K-GOLPH3-ST axis2022
- Author(s)
  Yuhan Sun, Tomoya Isaji, Tomohiko Fukuda and Jianguo Gu
- Organizer
  Sialoglyco2022
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] Focal adhesion kinaseのO-GlcNAc修飾による細胞機能の制御2021
- Author(s)
  伊左治知弥, 大山嘉順, 孫玉涵, 福田友彦, 黒田喜幸, 顧建国
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] Focal adhesion kinase (FAK)のO-GlcNAc 修飾による細胞接着斑の形成と細胞機能の制御2021
- Author(s)
  伊左治知弥, 大山嘉順, 孫玉涵, 福田友彦, 黒田喜幸, 顧建国
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] O-GlcNAcylation Regulates β1,4-GlcNAc-branched N-glycan Biosynthesis Via the OGT/SLC35A3/GnT-IV Axis2021
- Author(s)
  宋万里, 伊左治知弥, 中の三弥子, 福田友彦, 黒田喜幸, 顧建国
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] O-GlcNAcylation regulates β1,4-GlcNAc-branched N-glycan biosynthesis via the OGT/SLC35A3/GnT-IV Axis2021
- Author(s)
  宋万里, 伊左治知弥, 中の三弥子, 福田友彦, 黒田喜幸, 顧建国
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] Focal adhesion kinaseのO-GlcNAc修飾による細胞機能の制御2021
- Author(s)
  伊左治知弥, 大山嘉順, 孫玉涵, 福田友彦, 黒田喜幸, 顧建国
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] 膵がん細胞のがん幹細胞性の獲得と細胞移動・増殖におけるFUT8の役割2021
- Author(s)
  梁彩霞, 福田友彦, 伊左治知弥, 黒田喜幸, 顧建国
- Organizer
  第15回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] Focal adhesion kinase (FAK)のO-GlcNAc 修飾による細胞接着斑の形成と細胞機能の制御2021
- Author(s)
  伊左治知弥, 大山嘉順, 孫玉涵, 黒田喜幸, 福田友彦, 顧建国
- Organizer
  第40回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] O-GlcNAcylation Regulates β1,4-GlcNAc-branched N-glycan Biosynthesis Via the OGT/SLC35A3/GnT-IV Axis2021
- Author(s)
  宋万里, 伊左治知弥, 中の三弥子, 福田友彦, 黒田喜幸, 顧建国
- Organizer
  第15回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] 糖鎖による膜受容体の選別輸送ゾーンの特異性とその制御機構の解明2020
- Author(s)
  顧建国,　福田友彦,　伊左治知弥
- Organizer
  第２回オルガネラゾーン研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] FLT3を介したシグナル伝達におけるコアフコシル化の重要性2020
- Author(s)
  段程偉, 福田友彦, 伊左治知弥, 髙橋伸一郎, 顧建国
- Organizer
  第14回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] 糖鎖による膜受容体の選別輸送ゾーンの特異性とその制御機構の解明2020
- Author(s)
  顧建国,　福田友彦,　伊左治知弥
- Organizer
  第２回オルガネラゾーン研究会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] シアリル化等による膜受容体の選別輸送ゾーンの特異性とその制御について2020
- Author(s)
  伊左治知弥, 顧建国
- Organizer
  第２回オルガネラゾーン若手の会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] FUT8の発現は膵がん細胞の移動・増殖・がん幹細胞性に重要な役割を果たす。2020
- Author(s)
  梁彩霞, 福田友彦, 伊左治知弥, 顧建国
- Organizer
  第14回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] Deficiency of core fucosylation activates FLT3 signaling via induction of dimeric formation2020
- Author(s)
  Chengwei Duan, Tomohiko Fukuda, Tomoya Isaji, Shinichiro Takahashia and Jianguo Gu
- Organizer
  12th International Symposium on Glycosyltransferases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] インテグリンとFLT3受容体における糖鎖機能と制御機構2020
- Author(s)
  顧建国,　伊左治知弥,　福田友彦
- Organizer
  第93回日本生化学会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] FUT8の発現は膵がん細胞の移動・増殖・がん幹細胞性に重要な役割を果たす2020
- Author(s)
  梁彩霞, 福田友彦, 伊左治知弥, 顧建国
- Organizer
  第14回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] シアリル化等による膜受容体の選別輸送ゾーンの特異性とその制御について2020
- Author(s)
  伊左治知弥, 顧建国
- Organizer
  第二回オルガネラゾーン若手の会オルガネラゾーン若手の会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] インテグリンとFLT3受容体における糖鎖機能と制御機構2020
- Author(s)
  顧建国,　伊左治知弥,　福田友彦
- Organizer
  第93回日本生化学会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] 接着斑キナーゼ(FAK)のO-GlcNAc修飾による細胞機能への影響2020
- Author(s)
  大山嘉順, 伊左治知弥, 福田友彦, 顧建国
- Organizer
  第14回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] 膵がん細胞の遊走・増殖・がん幹細胞的性質保持におけるFUT8発現の重要性2020
- Author(s)
  福田友彦, 梁彩霞, 伊左治知弥, 顧建国
- Organizer
  第39回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] FLT3を介したシグナル伝達におけるコアフコシル化の重要性2020
- Author(s)
  段程偉, 福田友彦, 伊左治知弥, 髙橋伸一郎, 顧建国
- Organizer
  第14回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] 接着斑キナーゼ(FAK)のO-GlcNAc修飾による細胞機能への影響2020
- Author(s)
  大山嘉順, 伊左治知弥, 福田友彦, 顧建国
- Organizer
  第14回東北糖鎖研究会
- Data Source
  KAKENHI-PROJECT-19K07049
[Presentation] 糖鎖修飾によるインテグリンの選別輸送ゾーンの制御について2019
- Author(s)
  顧建国, 伊左治知弥, 福田友彦, 戸島拓郎, 中野明彦
- Organizer
  第3回オルガネラゾーン研究会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] 細胞内外の糖鎖発現とインテグリン機能とその制御2019
- Author(s)
  顧建国，伊左治知弥，福田友彦
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] PI4KIIαとインテグリンα3β1の複合体形成による癌細胞におけるN-型糖鎖の調節2019
- Author(s)
  伊左治知弥, ニンショウフン, 亀山昭彦, 福田友彦, 顧建国
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] コアフコースによるグリア細胞過活性化の抑制2019
- Author(s)
  福田友彦, 庄子隼人, 陸需, 張冬梅, 伊左治知弥, 顧建国
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] α1,6フコシルトランスフェラーゼ(Fut8)欠損によるグリア細胞の活性化2019
- Author(s)
  福田友彦、庄子隼人、陸需、張冬梅、伊左治知弥、顧建国
- Organizer
  第38回日本糖質学会年会
- Data Source
  KAKENHI-PROJECT-19H03184
[Presentation] GOLPH3 regulates integrin-mediated cell migration via up-regulation of sialylation of β1 integrin2013
- Author(s)
  Tomoya Isaji
- Organizer
  glyco22
- Place of Presentation
  大連　中国
- Data Source
  KAKENHI-PROJECT-24570169
[Presentation] GOLPH3はシアル酸転移酵素と相互作用し糖鎖構造とインテグリンの機能を制御する2013
- Author(s)
  伊左治知弥、竹原雅子花、小林沙織、近藤円、福田友彦、橋井則貴、高倉大輔、川崎ナナ、顧建国
- Organizer
  第31 回日本糖質学会年会
- Place of Presentation
  鹿児島市民文化ホール
- Data Source
  KAKENHI-PROJECT-24570169
[Presentation] N-型糖鎖による細胞-基質間接着の機能制御2012
- Author(s)
  伊左治知弥
- Organizer
  第11回化学系薬学若手研究者セミナー
- Place of Presentation
  東北大学薬学部
- Invited
- Data Source
  KAKENHI-PROJECT-24570169
[Presentation] GOLPH3はシアル酸転移酵素と相互作用し糖鎖構造とインテグリンの機能を制御する2012
- Author(s)
  伊左治知弥
- Organizer
  第31回日本糖質学会年会
- Place of Presentation
  鹿児島
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンに付加された糖鎖の意義について2011
- Author(s)
  伊左治知弥, 陸瑩瑩, 福田友彦, 顧建国
- Organizer
  第77回日本生化学会東北支部会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] GOLPH3によるインテグリンβ1の糖鎖付加および機能制御2011
- Author(s)
  伊左治知弥
- Organizer
  第84回日本日本生化学会大会
- Place of Presentation
  京都(京都国際会議場)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22770130
[Presentation] Effects of GOLPH3 on N-glycosylation of beta1 integrin and it 's functions2011
- Author(s)
  伊左治知弥
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22770130
[Presentation] Fut8欠損マウスにみられる統合失調症様行動と脳内神経伝達物質バランスの変化2011
- Author(s)
  福田友彦、伊左治知弥、顧建国
- Organizer
  第30回日本糖質学会年会
- Place of Presentation
  長岡
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] 癌遺伝子GOLPH3によるインテグリンbeta1の糖鎖変化とその機能調節2011
- Author(s)
  近藤円、伊左治知弥、福田友彦、顧建国
- Organizer
  第5回東北糖鎖研究会
- Place of Presentation
  東北大学
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] GOLPH3によるインテグリンβ1の糖鎖付加および機能制御2011
- Author(s)
  伊左治知弥、顧建国
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンα3鎖に付加されたN-結合型糖鎖の多機能性2011
- Author(s)
  陸瑩瑩、伊左治知弥、福田友彦、顧建国
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] 糖鎖による細胞-基質間接着の機能制御2011
- Author(s)
  伊左治知弥
- Organizer
  日本薬学会東北支部学術講演会
- Place of Presentation
  仙台(東北薬科大学)(招待講演)
- Year and Date
  2011-07-16
- Data Source
  KAKENHI-PROJECT-22770130
[Presentation] GOLPH3によるインテグリンβ1の糖鎖付加および機能制御2011
- Author(s)
  伊左治知弥、近藤円、福田友彦、顧建国
- Organizer
  第84回日本生化学会
- Place of Presentation
  京都国際会議場
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンα5β1に付加されたN-結合型糖鎖による機能制御2010
- Author(s)
  伊左治知弥、川村千尋、陸螢螢、福田友彦、顧建国
- Organizer
  第49回日本薬学会東北支部大会
- Place of Presentation
  奥羽大学
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンの機能を制御するN-結合型糖鎖2010
- Author(s)
  伊左治知弥、川村千尋、陸蛍蛍、福田友彦、顧建国
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] GOLPH3によるインテグリンβ1の糖鎖付加及び機能制御2010
- Author(s)
  我妻孝則、伊左治知弥、福田友彦、顧建国
- Organizer
  第4回東北糖鎖研究会
- Place of Presentation
  福島
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] Fut8 knockdownによるPC12細胞の機能変化2010
- Author(s)
  橋本弘和、福田友彦、岡安夏美、許青松、伊左治知弥、顧建国
- Organizer
  第4回東北糖鎖研究会
- Place of Presentation
  福島
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンα3鎖に付加されたN-結合型糖鎖の重要性2010
- Author(s)
  陸螢螢、伊左治知弥、福田友彦、顧建国
- Organizer
  第4回東北糖鎖研究会
- Place of Presentation
  福島
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] Wnt/β-catenin Signaling Down-regulates N-Acetylglucosaminyltransferase III Expression : Implication of Two Mutually Exclusive Pathways For the Regulation2010
- Author(s)
  許青松、伊左治知弥、陸蛍蛍、橋本弘和、福田友彦、顧建国
- Organizer
  第83回日本生化学会大会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンalpha5beta1に付加されたN-結合型糖鎖による機能制御2010
- Author(s)
  伊左治知弥
- Organizer
  第49回日本薬学会東北支部大会
- Place of Presentation
  奥羽大学
- Year and Date
  2010-10-24
- Data Source
  KAKENHI-PROJECT-22770130
[Presentation] インテグリンα5鎖のN-結合型糖鎖付加と細胞内シグナル伝達との関連性2010
- Author(s)
  川村千尋、伊左治知弥、福田友彦、顧建国
- Organizer
  第4回東北糖鎖研究会
- Place of Presentation
  福島
- Year and Date
  2010-12-04
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンの機能を制御するN-結合型糖鎖2010
- Author(s)
  伊左治知弥, 川村千尋, 陸蛍蛍, 福田友彦, 顧建国
- Organizer
  第69回日本癌学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] インテグリンa5の機能糖鎖モジュールに関する研究2009
- Author(s)
  伊左治知弥、顧建国
- Organizer
  第75回日本生化学会東北支部会
- Place of Presentation
  東北大学
- Year and Date
  2009-05-09
- Data Source
  KAKENHI-PROJECT-21370059
[Presentation] N-gl ycosyl ati on on I-like domain of beta1 integrin is essential for its expression and biological functions.2008
- Author(s)
  Tomoya Isaji, Yuya Sato, Tomohiko Fukuda and Jianguo Gu
- Organizer
  2008 Annual Meeting of the Society for Glycobiology
- Place of Presentation
  4. Fort Worth, Texas
- Year and Date
  2008-11-05
- Data Source
  KAKENHI-PROJECT-19790068
[Presentation] N-glycosylation on I-like domain of betal integrin is essential for its ex pression and biological functions2008
- Author(s)
  Tomoya Isaji
- Organizer
  Annual Meeting of the Society for Glycobiology
- Place of Presentation
  テキサス(アメリカ)
- Year and Date
  2008-11-15
- Data Source
  KAKENHI-PROJECT-19790068
[Presentation] インテグリンα5β1のN-結合型糖鎖修飾の機能解析2008
- Author(s)
  伊左治知弥、佐藤裕也、福田友彦、顧建国
- Organizer
  日本糖質学会第28回年会
- Place of Presentation
  筑波
- Data Source
  KAKENHI-PROJECT-19790068
[Presentation] N-Glycans of beta-propeller domain of alpha5 subunit are essential for alpha5beta1dimer formation and its biological functions.2007
- Author(s)
  Tomoya Isaji, Yuuya Sato, Naoyuki Taniguchi and Jianguo Gu
- Organizer
  Tomoya Isaji HGPI Meeting
- Place of Presentation
  Lubeck Germany
- Year and Date
  2007-12-07
- Data Source
  KAKENHI-PROJECT-19790068
[Presentation] N-glycans of β-propeller domain of α5 subunit are essential for α5β1 heterodimer formation and its biological functions2007
- Author(s)
  Tomoya Isaji
- Organizer
  14th European Carbohydrate Symposium
- Place of Presentation
  Lubeck, Germany
- Data Source
  KAKENHI-PROJECT-19790068
[Presentation] N-Glycans of beta-propeller domain of alpha5 subunit are essential for alpha5beta1dimer formation and its biological functions2007
- Author(s)
  Tomoya Isaji
- Organizer
  HGPI Meeting
- Place of Presentation
  Lubeck, Germany
- Year and Date
  2007-09-07
- Data Source
  KAKENHI-PROJECT-19790068
[Presentation] 細胞接着における糖転移酵素の発現制御とその意義
- Author(s)
  伊左治知弥、顧建国\
- Organizer
  第３９回日本応用酵素協会研究発表会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-24570169
[Presentation] GOLPH3による糖鎖修飾を介したインテグリンの機能調節
- Author(s)
  伊左治知弥、福田友彦、顧建国
- Organizer
  第86回日本生化学会大会（全国学会）　シンポジウム
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24570169

1. GU Jianguo (40260369)

# of Collaborated Projects: 3 results

# of Collaborated Products: 64 results
2. FUKUDA Tomohiko (40433510)

# of Collaborated Projects: 3 results

# of Collaborated Products: 57 results
3. OHNO Isao (00250762)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 苅谷慶喜 (00458217)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 山内広平 (20200579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 曽良一郎 (40322713)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 藤村務 (70245778)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 高橋伸一郎 (40375069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. 亀岡淳一 (30261621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. KAWASAKI Nana

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 山口芳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 中の三弥子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Isaji Tomoya 伊左治 知弥

ISAJI Tomoya 伊左治 知弥

伊佐治 知弥 イサジ トモヤ

Research Projects

Research Products

Co-Researchers

シアリル化N-型糖鎖修飾の特異性とその制御機構Principal Investigator

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Analysis of underlying molecular mechanism for the regulation of chemoresistance by GnT-III

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Regulatory mechanism of sialylation of N-glycans by focal adhesion kinase (FAK) and its biological significancePrincipal Investigator

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Regulation and significance of new sialylated glycan biosynthesis via integrin alpha3Principal Investigator

Principal Investigator

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Functions of glycosylation in integrin-mediated outside-in and inside-out signaling

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Role of functional single-nucleotide polymorphism of the opioid receptor gene in stress-induced exacerbation of asthma

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Functional analysis of N-glycan on integrin alpha5beta1 for supramolecular assembly and cell proliferationPrincipal Investigator

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インテグリンα5β1を介した超分子複合体の特異性とその意義Principal Investigator

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Change of oligosaccharides in cell adhesion, and its roles

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Identification of functional module of N-glycans on α5β1 integrinPrincipal Investigator

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[Book] インテグリンのN-結合型糖鎖による細胞接着機能の調節2008

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[Book] 細胞接着2007

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[Book] 細胞移動2007

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[Journal Article] Exogenous l-fucose attenuates neuroinflammation induced by lipopolysaccharide2024

Author(s)

Isaji Tomoya 伊左治知弥

ISAJI Tomoya 伊左治知弥

伊佐治知弥イサジトモヤ