Ishii Takenobu 石井武展

… Alternative Names

ISHII TAKENOBU 石井武展

石井武展イシイタケノブ

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Researcher Number	80433978
Other IDs
Affiliation (Current)	2025: 東京歯科大学, 歯学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2025: 東京歯科大学, 歯学部, 准教授 2017 – 2020: 東京歯科大学, 歯学部, 講師 2014 – 2015: 東京歯科大学, 歯学部, 助教 2012: 東京歯科大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 57070:Developmental dentistry-related / Orthodontics/Pediatric dentistry / Orthodontic/Pediatric dentistry Except Principal Investigator Basic Section 57070:Developmental dentistry-related / Orthodontics/Pediatric dentistry
Keywords	Principal Investigator ANGPTL-7 / 機械的刺激 / アンドロジェン / 軟骨細胞層 / 顎関節 / 変形性顎関節炎 / 性ホルモン / アロマターゼ / CAR-1 / ANGPTL7 … More / テストステtロン / car1 / angptl7 / アンドロゲン / エストロゲン / メカニカルストレス / 変形性顎関節症 / ゲノム編集 / Gain of function / 未分化間葉系幹細胞 / 疾患特異的iPS細胞 / FGFR2 / iPS細胞 / Apert症候群 / 歯科矯正学 / 歯根露出 / 上顎側方拡大 / 上顎側方拡大装置 / MC3T3-E1 / 頬側歯槽骨吸収 / 局所投与モデル / マウス実験モデル / フルバスタチン … More Except Principal Investigator 破骨細胞 / γδT細胞 / マクロファージ遊走阻止因子 / 骨代謝 / 免疫学 / 老化 / CXCR4 / γδ T細胞 / 骨芽細胞 Less

矯正学的歯の移動における歯根膜内Gli1陽性幹細胞の増殖と分化機序の時空間的解明Principal Investigator
- Principal Investigator
  
  石井武展
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tokyo Dental College
To elucidate the mechanisms of the bone destruction caused by CXCR4-positive cells associated with aging and investigation of the possibility of molecular-targeted agents.
- Principal Investigator
  
  西村寿晃
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tohoku University
Pathogenesis of temporomandibular joint osteoarthritis caused by sex hormones and mechanical stimulation and treatment strategyPrincipal Investigator
- Principal Investigator
  
  Ishii Takenobu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tokyo Dental College
Elucidation of the function of gamma delta T cells that control the migration of osteoclast precursor cells to bone tissue and investigation of the possibility of molecular-targeted agents
- Principal Investigator
  
  Nishimura Kazuaki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Tohoku University
Elucidation of the molecular mechanism of bone metabolism regulated by gamma delta T cells and investigation of the possibility of a molecular targeted agent for metabolic bone diseases
- Principal Investigator
  
  NISHIMURA KAZUAKI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tohoku University
Establishment and application of disease-specific iPS cells for Apert syndromePrincipal Investigator
- Principal Investigator
  
  Ishii Takenobu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tokyo Dental College
A study on a new orthodontic treatment involving local application of fluvastatinPrincipal Investigator
- Principal Investigator
  
  ISHII TAKENOBU
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Tokyo Dental College
局所的フルバスタチン応用による新たな矯正歯科治療の検討Principal Investigator
- Principal Investigator
  
  石井武展
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Orthodontic/Pediatric dentistry
- Research Institution
  Tokyo Dental College

All 2024 2022 2021 2020 2019 2018 2014 Other

All Journal Article Presentation

[Journal Article] 性ホルモンと機械的刺激による変形性顎関節症の病態発生機序の解明とその治療戦略2024
- Author(s)
  石井武展
- Journal Title
  
  月刊　細胞
  
  Volume: 56 Pages: 58-61
- Data Source
  KAKENHI-PROJECT-20K10215
[Journal Article] Overload of the Temporomandibular Joints Accumulates γδ T Cells in a Mouse Model of Rheumatoid Arthritis: A Morphological and Histological Evaluation2022
- Author(s)
  Nagai Kohei、Ishii Takenobu、Ohno Tatsukuni、Nishii Yasushi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 12 Pages: 753754-753754
- DOI
  10.3389/fimmu.2021.753754
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K10215
[Journal Article] Effect of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice2021
- Author(s)
  Ootake Tomohisa, Ishii Takenobu, Sueishi Kenji, Watanabe Akira, Ishizuyka Youichi, Amano Katsuhiko, Nagao Masashi, Nishimura Kazuaki, Nishii Yasushi
- Journal Title
  
  Ostteoarthritis and Cartilage
  
  Volume: 29 Pages: 1575-1589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10215
[Journal Article] Effects of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice2021
- Author(s)
  Tomohisa Ootake, Takenobu Ishii, Kenji Sueishi, Akira Watanabe, Yoichi Ishizuka, Katsuhiko Amano, Masashi Nagao, Kazuaki Nishimura, Yasushi Nishii
- Journal Title
  
  Osteoarthritis and Cartilage
  
  Volume: 29 Issue: 11 Pages: 1575-1589
- DOI
  10.1016/j.joca.2021.08.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K10220
[Journal Article] 片側性唇顎口蓋裂患者の口蓋裂一次手術（Push-Buck法とPerko法）の違いによる顎発育の比較について2014
- Author(s)
  松浦彰子、斎藤裕香、石井武展、坂本輝雄、末石研二、中野洋子、須賀賢一郎、内山健志
- Journal Title
  
  歯科学報
  
  Volume: 114巻4号 Pages: 325-332
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861800
[Journal Article] Effect of orthodontic treatment on occlusal condition and masticatory function2014
- Author(s)
  Makino E, Nomura M, Motegi E, Iijima Y, Ishii T, Koizumi Y, Hayashi,M, Sueishi K, Kawano M, Yanagisawa S
- Journal Title
  
  Bulletin Tokyo Dental College
  
  Volume: 55(4) Pages: 185-197
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] 変形性顎関節炎に対するテストステロン由来の17βエストラジオールによる顎関節への影響2022
- Author(s)
  戸村拓真，石井武展，西井　康
- Organizer
  創立90周年記念第81回東京矯正歯科学会学術大会
- Data Source
  KAKENHI-PROJECT-20K10215
[Presentation] テストステロン由来のエストロゲンによる顎関節保護効果について2022
- Author(s)
  戸村拓真，石井武展，西井　康
- Organizer
  東京歯科大学学会・例会
- Data Source
  KAKENHI-PROJECT-20K10215
[Presentation] テストステロン由来のエストロゲンによる変形性顎関節症への影響2022
- Author(s)
  戸村拓真，石井武展，笠原典夫，西井　康
- Organizer
  第81回日本矯正歯科学会学術大会&第9回日韓ジョイントシンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10215
[Presentation] 顎関節リウマチの骨、軟骨破壊に対する機械的刺激の影響について2021
- Author(s)
  永井航平，石井武展，西井康
- Organizer
  第310回東京歯科大学学会
- Data Source
  KAKENHI-PROJECT-20K10215
[Presentation] 変形性顎関節炎は性ホルモンと機械的刺激により惹起される2020
- Author(s)
  石井武展
- Organizer
  日本顎関節学会
- Data Source
  KAKENHI-PROJECT-20K10215
[Presentation] Impaction of ultrasound therapy on medication-related osteonecrosis of the jaw2020
- Author(s)
  Kazuki Satomi, Kazuaki Nishimura, Marie Tabaru, Kentaro Nakamura, Takenobu Ishii, Kaoru Igarashi
- Organizer
  The 9th Internationa Orthodontic Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10220
[Presentation] Induction of Osteoblasts and Chondrocytes from Apert Syndrome-specific iPS Cells.2019
- Author(s)
  Takenobu Ishii
- Organizer
  The 97rd IADR/AADR/CADR General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11948
[Presentation] Establishment of Apert syndrome disease-specific iPS cells.2018
- Author(s)
  Takenobu Ishii, Hiroyuki Ogura, Shoko Onodera, Kenji Sueishi, Toshifumi Azuma
- Organizer
  96th IADR/PER General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11948
[Presentation] Establishment of Apert syndrome disease-specific iPS cells.2018
- Author(s)
  石井武展
- Organizer
  the 2018 IADR/PER General Session & Exhibition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K11948
[Presentation] 変形性顎関節症の軟骨破壊に対する性ホルモンと機械的刺激の作用機序の解明2018
- Author(s)
  石井武展, 大竹智久, 崔大煥, 石川宗理, 末石研二, 渡邉章, 斎藤力, 石塚洋一, 天野克比古, 長尾雅史, 西村壽晃, 河井敬久
- Organizer
  東京歯科大学学会
- Data Source
  KAKENHI-PROJECT-17K11930
[Presentation] 市川市「すこやか口腔検診」における咬合調査について2014
- Author(s)
  宮本佳奈、茂木悦子、有泉大、堀内彬代、石井武展、野村真弓、末石研二、杉原直樹、長谷川勝
- Organizer
  日本矯正歯科学会
- Place of Presentation
  幕張メッセ
- Year and Date
  2014-10-20
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] 片側性唇顎口蓋裂患者の矯正治療後の咬合について
- Author(s)
  亀井牧子、北詰美弥、吉住淳、石井武展、坂本輝雄、末石研二
- Organizer
  日本矯正歯科学会
- Place of Presentation
  幕張メッセ
- Year and Date
  2014-10-20 – 2014-10-22
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] Anti-OC-STAMP Monoclonal Antibody Inhibits Bone Resorption of Ligature-induced Mouse Periodontitis
- Author(s)
  T. Ishii, M. Ruiz-Torruella, W. Wisitrasameewong, Y. Matsuda, A. Movila, T. Yamaguchi, K. Nishimura, E. Motegi, K. Sueishi, T. Kawai
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] Anti-Semaphorin-4D mAb Prevents Bone Loss Without Affecting Inflammation in Mouse Periodontitis
- Author(s)
  M. Ruiz-Torruella, T. Ishii, D. Kim, M. Gil, W. Wisitrasameewong, A. Movila, T. Yamaguchi, X. Han, T. Kawai
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] Hyperlipidemic State Counteracts Ligature-induced Periodontal Bone Loss in Mice
- Author(s)
  W. Wisitrasameewong, T. Ishii, Y. Matsuda, M. Ruiz-Torruella, T. Yamaguchi, A. Movila, D. Kim, R. Mahanonda, T. Kawai
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] Effects of Extracellular Adenosine on Mouse Model of Periradicular Periodontitis
- Author(s)
  A. Albassam, M. Howait, Y. Matsuda, T. Ishii, A. Movila, R. White, T. pagonis, H. Sasaki, L. F. Thompson, T. Kawai
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] 骨延長を施行したTreacher Collins syndromeの１症例
- Author(s)
  坂本輝雄、石井武展、西井康、末石研二、岩本昌士、山本雅絵、高木多加志
- Organizer
  日本顎変形症学会
- Place of Presentation
  アクロス福岡
- Year and Date
  2014-06-10 – 2014-06-11
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] 上顎無歯顎の骨格性下顎前突症に対して舌縮小術を併用した外科的矯正治療
- Author(s)
  渋井武夫、岩本昌士、菅原圭亮、村瀬千明、飯塚美穂、石井武展、高野伸夫、片倉朗
- Organizer
  日本顎変形症学会
- Place of Presentation
  アクロス福岡
- Year and Date
  2014-06-10 – 2014-06-11
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] Oral Myofunctional Status Found in Children of Mixed Dentition
- Author(s)
  E. Motegi, K. Miyamoto, D. Ariizumi, A. Horiuchi, T. Ishii, M. Nomura, K. Sueishi, N. Sugihara, M. Hasegawa
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26861800
[Presentation] Recruitment of Circulating Osteoclast Precursor Cells in Titanium Microparticle-induced Osteolytic Lesion
- Author(s)
  A. Movila, L. Gunarajasimgam, T. Ishii, D. H. Nguyen, T. Van Dyke, T. Kawai
- Organizer
  IADR/AADR/CADR General Session & Exhibition
- Place of Presentation
  Boston
- Year and Date
  2015-03-11 – 2015-03-14
- Data Source
  KAKENHI-PROJECT-26861800

1. NISHIMURA KAZUAKI (50367611)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
2. 五十嵐薫 (70202851)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. 一文字功 (40753215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 山口朗 (00142430)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 末石研二 (00154427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 小野寺晶子 (90637662)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 齋藤暁子 (90722835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松永智 (70453751)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中村貴 (80431948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 溝口利英 (90329475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 里見和紀 (20961692)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ishii Takenobu 石井 武展

ISHII TAKENOBU 石井 武展

石井 武展 イシイ タケノブ

Research Projects

Research Products

Co-Researchers

矯正学的歯の移動における歯根膜内Gli1陽性幹細胞の増殖と分化機序の時空間的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

To elucidate the mechanisms of the bone destruction caused by CXCR4-positive cells associated with aging and investigation of the possibility of molecular-targeted agents.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenesis of temporomandibular joint osteoarthritis caused by sex hormones and mechanical stimulation and treatment strategyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the function of gamma delta T cells that control the migration of osteoclast precursor cells to bone tissue and investigation of the possibility of molecular-targeted agents

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the molecular mechanism of bone metabolism regulated by gamma delta T cells and investigation of the possibility of a molecular targeted agent for metabolic bone diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment and application of disease-specific iPS cells for Apert syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A study on a new orthodontic treatment involving local application of fluvastatinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

局所的フルバスタチン応用による新たな矯正歯科治療の検討Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 性ホルモンと機械的刺激による変形性顎関節症の病態発生機序の解明とその治療戦略2024

Author(s)

Journal Title

Data Source

[Journal Article] Overload of the Temporomandibular Joints Accumulates γδ T Cells in a Mouse Model of Rheumatoid Arthritis: A Morphological and Histological Evaluation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice2021

Author(s)

Journal Title

Data Source

[Journal Article] Effects of mechanical stress and deficiency of dihydrotestosterone or 17β-estradiol on Temporomandibular Joint Osteoarthritis in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 片側性唇顎口蓋裂患者の口蓋裂一次手術（Push-Buck法とPerko法）の違いによる顎発育の比較について2014

Author(s)

Journal Title

Data Source

[Journal Article] Effect of orthodontic treatment on occlusal condition and masticatory function2014

Author(s)

Journal Title

Data Source

Ishii Takenobu 石井武展

ISHII TAKENOBU 石井武展

石井武展イシイタケノブ

[Presentation] 変形性顎関節炎に対するテストステロン由来の17βエストラジオールによる顎関節への影響2022