Kobayashi Tetsuo 小林哲夫

… Alternative Names

KOBAYASHI Tetsuo 小林哲夫

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Researcher Number	80433994
Other IDs
Affiliation (Current)	2025: 順天堂大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2025: 順天堂大学, 医学部, 准教授 2022 – 2023: 順天堂大学, 医学部, 准教授 2018 – 2021: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 2013 – 2017: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教 2006 – 2010: 東京大学, 大学院・薬学系研究科, 助教 2007: 東京大学, 大学院・薬学系・研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Biological Sciences / Biological pharmacy / Basic Section 50010:Tumor biology-related Except Principal Investigator Functional biochemistry / Biological pharmacy / Biological Sciences
Keywords	Principal Investigator 一次繊毛 / 膵管がん / 膵管癌 / 癌微小環境 / 乳癌 / 癌関連線維芽細胞 / CEP164 / KIF24 / ヘッジホッグシグナル / シグナル伝達 / GPCR / 繊毛小胞 / 中心小体 … More Except Principal Investigator … More シグナル伝達 / ゲノムプロジェクト / G蛋白質 / 遺伝子 / Gサイクル / RNAi / スクリーニング / 線虫 / 上皮細胞 / 薬物トランスポーター / 染色体分離 / 細胞・組織 / 生体分子 / 蛋白質 / リソソーム / 小胞輸送 / タンパク質 / GTPase cycle / G protein / Genome project / Gene / Protein / Signal transduction / 制御分子 / GPCR / Gタンパク質 / アピカル輸送 / Processing body / メンブラントラフィック / 細胞極性 / 細胞内輸送 / 神経細胞死 Less

乳癌関連線維芽細胞における一次繊毛増加の分子機構と癌に及ぼす影響の解明Principal Investigator
- Principal Investigator
  
  小林哲夫
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Juntendo University
膵管がんにおける一次繊毛消失の分子機構と影響の解明Principal Investigator
- Principal Investigator
  
  小林哲夫
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Juntendo University
  Nara Institute of Science and Technology
Molecular mechanism and impact of loss of primary cilia in PDAC cellsPrincipal Investigator
- Principal Investigator
  
  Kobayashi Tetsuo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Nara Institute of Science and Technology
Molecular mechanism of ciliary vesicle formation in mammalian cellsPrincipal Investigator
- Principal Investigator
  
  Kobayashi Tetsuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nara Institute of Science and Technology
一次繊毛局在性GPCRのシグナル制御と輸送メカニズムの解明Principal Investigator
- Principal Investigator
  
  小林哲夫
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
膵管癌細胞における一次繊毛消失機構の解明と癌治療への応用Principal Investigator
- Principal Investigator
  
  小林哲夫
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
Analysis of the regulatory mechanisms of G protein-coupled receptor signaling
- Principal Investigator
  
  Itoh Hiroshi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nara Institute of Science and Technology
Regulation of primary cilia formation cycle by Kif24Principal Investigator
- Principal Investigator
  
  KOBAYASHI Tetsuo
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nara Institute of Science and Technology
Regulation of intracellular vesicle transport by small GTPase cycles
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
遺伝学的手法による上皮細胞の蛋白質選別輸送の解析
- Principal Investigator
  
  紺谷圏二
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Comprehensive analysis of genes involved in the regulation of subcellular localization of drug transporters
- Principal Investigator
  
  KONTANI Kenji
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  The University of Tokyo
細胞の増殖と分裂に介在する新奇低分子量G蛋白質群の機能解析
- Principal Investigator
  
  紺谷圏二
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Membrane-Transport Signaling Involving the GTPase Cycle of G proteins
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Functional biochemistry
- Research Institution
  The University of Tokyo
Functional analysis of atypical G proteins involved in cell signaling network
- Principal Investigator
  
  KATADA Toshiaki
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo

[Journal Article] CEP164-GLI2 association ensures the hedgehog signaling in pancreatic cancer cells2023
- Author(s)
  Fushimi T, Kobayashi T, Itoh H
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 666 Pages: 179-185
- DOI
  10.1016/j.bbrc.2023.05.031
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06528, KAKENHI-PROJECT-21K06837
[Journal Article] KIF24 depletion induces clustering of supernumerary centrosomes in PDAC cells2022
- Author(s)
  Mashima Y, Nohira H, Sugihara H, Dynlacht BD, Kobayashi T, Itoh H
- Journal Title
  
  Life Science Alliance
  
  Volume: 5 Issue: 11 Pages: e202201470-e202201470
- DOI
  10.26508/lsa.202201470
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06528, KAKENHI-PROJECT-21K06837
[Journal Article] The atypical small GTPase RABL3 interacts with RAB11 to regulate early ciliogenesis in human cells2022
- Author(s)
  Kobayashi T, Ikeda T, Ota R, Yasukawa T, Itoh H
- Journal Title
  
  Journal of Cell Science
  
  Volume: 135 Issue: 18
- DOI
  10.1242/jcs.260021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06528
[Journal Article] HTR6 and SSTR3 ciliary targeting relies on both IC3 loops and C-terminal tails2021
- Author(s)
  Barbeito P, Tachibana Y, Martin-Morales R, Moreno P, Mykytyn K, Kobayashi T, Garcia-Gonzalo FR.
- Journal Title
  
  Life Science Alliance
  
  Volume: 4 Issue: 3 Pages: e202000746-e202000746
- DOI
  10.26508/lsa.202000746
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06627
[Journal Article] CEP164 deficiency causes hyperproliferation of pancreatic cancer cells2020
- Author(s)
  Kobayashi T, Tanaka K, Mashima Y, Shoda A, Tokuda M, Itoh H.
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 8 Pages: 587691-587691
- DOI
  10.3389/fcell.2020.587691
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06627
[Journal Article] 一次繊毛の構築2019
- Author(s)
  小林　哲夫
- Journal Title
  
  腎と透析
  
  Volume: 87 Pages: 697-700
- Data Source
  KAKENHI-PROJECT-18K06627
[Journal Article] RABL2 positively controls localization of GPCRs in mammalian primary cilia2019
- Author(s)
  Dateyama I, Sugihara Y, Chiba S, Ota R, Nakagawa R, Kobayashi T, Itoh H
- Journal Title
  
  Journal of Cell Science
  
  Volume: 132 Issue: 2
- DOI
  10.1242/jcs.224428
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06627
[Journal Article] 一次繊毛構築のはじまりの制御機構2018
- Author(s)
  小林　哲夫
- Journal Title
  
  実験医学
  
  Volume: 36 Pages: 921-925
- Data Source
  KAKENHI-PROJECT-15K07931
[Journal Article] 一次繊毛構築のはじまりの制御機構2018
- Author(s)
  小林　哲夫
- Journal Title
  
  実験医学
  
  Volume: 36 Pages: 921-925
- Data Source
  KAKENHI-PROJECT-18K06627
[Journal Article] Molecular mechanism of loss of primary cilia in cancer cells2018
- Author(s)
  小林　哲夫、伊東　広
- Journal Title
  
  生化学
  
  Volume: 90 Issue: 2 Pages: 169-172
- DOI
  10.14952/SEIKAGAKU.2018.900169
- NAID
  40021617407
- ISSN
  0037-1017
- Year and Date
  2018-04-25
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06627
[Journal Article] Loss of a primary cilium in PDAC2017
- Author(s)
  Kobayashi T, Itoh H
- Journal Title
  
  Cell Cycle
  
  Volume: - Issue: 9 Pages: 1-2
- DOI
  10.1080/15384101.2017.1304738
- Open Access
- Data Source
  KAKENHI-PUBLICLY-15H01215, KAKENHI-PROJECT-15K07931
[Journal Article] HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma2017
- Author(s)
  Kobayashi T, Nakazono K, Tokuda M, Mashima Y, Dynlacht BD, Itoh H
- Journal Title
  
  EMBO Reports
  
  Volume: 18 Issue: 2 Pages: 334-343
- DOI
  10.15252/embr.201541922
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01215, KAKENHI-PROJECT-15K07931
[Journal Article] Agonistic Antibodies Reveal the Function of GPR56 in Human Glioma U87-MG Cells2015
- Author(s)
  Ohta S, Sakaguchi S, Kobayashi Y, Mizuno N, Tago K, Itoh H.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 38 Issue: 4 Pages: 594-600
- DOI
  10.1248/bpb.b14-00752
- NAID
  130005062265
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590113, KAKENHI-PUBLICLY-25121724, KAKENHI-PROJECT-25293013, KAKENHI-PROJECT-26440062
[Journal Article] The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly2014
- Author(s)
  Tetsuo Kobayashi, Sehyun Kim, Yu-Chun Lin, Takanari Inoue, Brian David Dynlacht
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 204 Issue: 2 Pages: 215-229
- DOI
  10.1083/jcb.201304153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860048
[Journal Article] The Arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans2010
- Author(s)
  Nakae I, Fujino T, Kobayashi T, Sasaki A, Kikko Y, Fukuyama M, Gengyo-Ando K, Mitani S, Kontani K, Katada T
- Journal Title
  
  Mol.Biol.Cell 21
  
  Pages: 2434-2442
- Data Source
  KAKENHI-PROJECT-20247011
[Journal Article] The Arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans. Mol. Biol. Cell2010
- Author(s)
  Nakae I, Fujino T, Kobayashi T, Sasaki A, Kikko Y, Fukuyama M, Gengyo-Ando K, Mitani S, Kontani K, Katada T.
- Journal Title
  
  Mol. Biol. Cell (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079002
[Journal Article] Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome2009
- Author(s)
  Kobayashi, T., et al.
- Journal Title
  
  Biochem Biophys Res Commun 381
  
  Pages: 439-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20657025
[Journal Article] Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome.2009
- Author(s)
  Kobayashi T, Hori Y, Ueda N, Kajiho H, Muraoka S, Shima F, Kataoka T, Kontani K, Katada T
- Journal Title
  
  Biochem Biophys Res Commun. 381
  
  Pages: 439-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Journal Article] Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Ar16 causing Bardet-Biedl syndrome2009
- Author(s)
  Kobayashi T., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 381
  
  Pages: 439-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20247011
[Journal Article] Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome.2009
- Author(s)
  Kobayashi T, Hori Y, Ueda N, Kajiho H, Muraoka S, Shima F, Kataoka T, Kontani K, Katada T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 381(3)
  
  Pages: 439-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079002
[Journal Article] Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome2009
- Author(s)
  Kobayashi T., et al.
- Journal Title
  
  Biochem.Biophys.Res.Commun. 381
  
  Pages: 439-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079002
[Journal Article] Biochemical characterization of missense mutations in the Arf/Arl-family small GTPase Arl6 causing Bardet-Biedl syndrome2009
- Author(s)
  Kobayashi T, Hori Y, Ueda N, Kajiho H, Muraoka S, Shima F, Kataoka T, Kontani K, Katada T
- Journal Title
  
  Biochem.Biophys.Res.Commun. 381(3)
  
  Pages: 439-442
- Data Source
  KAKENHI-PROJECT-20247011
[Journal Article] Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation.2008
- Author(s)
  Hori Y, Kobayashi T, Kikko Y, Kontani K, Katada T
- Journal Title
  
  Biochem. Biophys. Res. Commun. 373
  
  Pages: 119-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Journal Article] Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation.2008
- Author(s)
  Hori Y, Kobayashi T, Kikko Y, Kontani K, Katada T.
- Journal Title
  
  Biochem. Biophys. Res. Commun. 373
  
  Pages: 119-124
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079002
[Journal Article] Domain architecture of the atypical Arf-family GTPase Arl13b involved in cilia formation2008
- Author(s)
  Hori Y, Kobayashi T, Kikko Y, Kontani K, Katada T
- Journal Title
  
  Biochem.Biophys.Res.Commun. 373
  
  Pages: 119-124
- Data Source
  KAKENHI-PROJECT-20247011
[Journal Article] Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase2007
- Author(s)
  Shintani M, Tada M, Kobayashi T, Kajiho H, Kontani K, Katada T.
- Journal Title
  
  Biochem. Biophys. Res. Commun 357
  
  Pages: 661-667
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18207008
[Journal Article] Role of activation of PIP5K gamma661 by AP-2 complex in synaptic vesicle endocytosis.2007
- Author(s)
  Nakano-Kobayashi A, et. al.
- Journal Title
  
  EMBO J. 26
  
  Pages: 1105-1116
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18207008
[Journal Article] C. elegans mitochondrial factor WAH-1 promotes phosphatidylserine externalization in apoptotic cells Through phospholipid scramblase SCRM-1.2007
- Author(s)
  Wang X, Wang J, Gengyo-Ando K, Gu L, Sun C-L, Yang C, Shi Y, Kobayashi T, Shi Y, Mitani S, Xie X-S, Xue D
- Journal Title
  
  Nat. Cell Biol. 9
  
  Pages: 541-549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Journal Article] IFT-81 and IFT-74 are required for intraflagellar transport in C. elegans2007
- Author(s)
  Kobayashi T, et. al.
- Journal Title
  
  Genes Cells 12
  
  Pages: 593-602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18013009
[Journal Article] Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis2007
- Author(s)
  Nakano-Kobayashi A, Yamazaki M, Unoki T, Hongu T, Murata C, Taguchi R, Katada T, Frohman MA, Yokozeki T, Kanaho Y.
- Journal Title
  
  EMBO J. 26
  
  Pages: 1105-1116
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18207008
[Journal Article] Role of activation of PIP5Kg661 by AP-2 complex in synaptic vesicle endocytosis2007
- Author(s)
  Nakano-Kobayashi, A., et al.
- Journal Title
  
  EMBO J. 26
  
  Pages: 1105-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Journal Article] Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase.2007
- Author(s)
  Shintani M, Tada M, Kobayashi T, Kajiho H, Kontani K, Katada T.
- Journal Title
  
  Biochem Biophys Res Commun. 357
  
  Pages: 661-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079002
[Journal Article] Characterization of Rab45/RASEF containing EF-hand domain and a coiled-coil motif as a self-associating GTPase.2007
- Author(s)
  Shintani M, Tada M, Kobayashi T, Kajiho H, Kontani K, Katada T
- Journal Title
  
  Biochem Biophys Res Commun. 357
  
  Pages: 661-667
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Journal Article] IFT-81 and IFT-74 are required for intraflagellar transport in C. elegans.2007
- Author(s)
  Kobayashi T, Gengyo-Ando K, Ishihara T, Katsura I, Mitani S
- Journal Title
  
  Genes Cells 12
  
  Pages: 593-602
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Journal Article] Role of activation of PIP5Ky661 by AP-2 complex in synaptic vesicle endocytosis.2007
- Author(s)
  Nakano-Kobayashi A, et al.
- Journal Title
  
  EMBO J. 26
  
  Pages: 1105-1116
- Data Source
  KAKENHI-PROJECT-18207008
[Journal Article] Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis.2007
- Author(s)
  Nakano-Kobayashi A, Yamazaki M, Unoki T, Hongu T, Murata C, Taguchi R, Katada T, Frohman MA, Yokozeki T, Kanaho Y.
- Journal Title
  
  EMBO J. 26
  
  Pages: 1105-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17079002
[Journal Article] Role of activation of PIP5Kγ661 by AP-2 complex in synaptic vesicle endocytosis.2007
- Author(s)
  Nakano-Kobayashi A, et al.
- Journal Title
  
  EMBO J. 26
  
  Pages: 1105-1116
- Data Source
  KAKENHI-PROJECT-18013009
[Journal Article] The SM protein VPS-45 is required for RAB-5-dependent endocytic transport in Caenorhabditis elegans.2007
- Author(s)
  Gengyo-Ando K, Kuroyanagi H, Kobayashi T, Murate H, Fujimoto K, Okabe S, Mitani S
- Journal Title
  
  EMBO Rep. 8
  
  Pages: 152-157
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Journal Article] 低分子量gタンパク質研究の進歩2007
- Author(s)
  多田稔、小林哲夫、紺谷圏二、堅田利明
- Journal Title
  
  日薬理誌 130
  
  Pages: 373-379
- NAID
  10020167192
- Data Source
  KAKENHI-PROJECT-17079002
[Journal Article] Role of activation of PIP5Kgamma661 by AP-2 complex in synaptic vesicle endocytosis.2007
- Author(s)
  Nakano-Kobayashi A, Yamazaki M, Unoki T, Hongu T, Murata C, Taguchi R, Katada T, Frohman MA, Yokozeki T, Kanaho Y
- Journal Title
  
  EMBO J. 26
  
  Pages: 1105-1116
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390017
[Presentation] がん細胞における一次繊毛に依存しないヘッジホッグシグナル制御機構2023
- Author(s)
  小林　哲夫、伏見　勇彦、伊東　広
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06528
[Presentation] 膵臓がん細胞における中心小体タンパク質CEP164を介したヘッジホッグシグナル制御2022
- Author(s)
  伏見　勇彦、小林　哲夫、伊東　広
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06528
[Presentation] 膵管がんにおける新しいヘッジホッグシグナル伝達機構2021
- Author(s)
  小林　哲夫、田中　弘祐、伏見　勇彦、伊東　広
- Organizer
  第94回日本生化学会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06528
[Presentation] RABファミリー低分子量GTP結合タンパク質群による一次繊毛形成の制御2019
- Author(s)
  小林　哲夫、池田　達哉、伊東　広
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06627
[Presentation] 膵管癌細胞における一次繊毛消失メカニズムの解析2018
- Author(s)
  馬島　友、小林　哲夫、伊東　広
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-15K07931
[Presentation] Molecular mechanism of loss of primary cilia in pancreatic ductal adenocarcinoma cells2018
- Author(s)
  Tetsuo Kobayashi, Yu Mashima, Ayano Shoda, Brian David Dynlacht, Hiroshi Itoh
- Organizer
  Cold Spring Harbor Asia Conference “Cilia and Centrosomes”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07931
[Presentation] 膵管癌における一次繊毛消失機構の解析2018
- Author(s)
  小林　哲夫、馬島　友、庄田　彩乃、Brian David Dynlacht、伊東　広
- Organizer
  第69回日本細胞生物学会
- Data Source
  KAKENHI-PROJECT-15K07931
[Presentation] 新規低分子量Gタンパク質Rabl3による一次繊毛形成制御機構の解析2018
- Author(s)
  池田　達哉、太田　麗央、安川　貴文、小林　哲夫、伊東　広
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-18K06627
[Presentation] HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma2016
- Author(s)
  Kobayashi T, Nakazono K, Tokuda M, Mashima Y, Dynlacht BD, Itoh H
- Organizer
  The 28th CDB meeting
- Place of Presentation
  理研CDB、神戸市、兵庫県
- Year and Date
  2016-11-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07931
[Presentation] HDAC2 promotes loss of primary cilia in pancreatic ductal adenocarcinoma2016
- Author(s)
  Kobayashi T, Nakazono K, Tokuda M, Mashima Y, Dynlacht BD, Itoh H
- Organizer
  The 28th CDB meeting
- Place of Presentation
  理研CDB、神戸市、兵庫県
- Year and Date
  2016-11-28
- Data Source
  KAKENHI-PUBLICLY-15H01215
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析2015
- Author(s)
  小林　哲夫、中薗　昂亮、徳田　澪、馬島　友、伊達山　泉、Brian David Dynlacht、伊東　広
- Organizer
  第6回繊毛研究会
- Place of Presentation
  基礎生物学研究所、岡崎市、愛知県
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PROJECT-15K07931
[Presentation] Analysis of serotonin signaling mediated through primary cilia2015
- Author(s)
  Dateyama Izumi, Tetsuo Kobayashi, Hiroshi Itoh
- Organizer
  The 4th International Conference on Pharmacy and Advanced Pharmaceutical Sciences
- Place of Presentation
  Yogyakarta, Indonesia
- Year and Date
  2015-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01215
[Presentation] 膵管癌細胞における一次繊毛消失メカニズムの解析2015
- Author(s)
  小林　哲夫、中薗　昂亮、徳田　澪、馬島　友、Brian David Dynlacht、伊東　広
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-26112712
[Presentation] Analysis of melecular mechanisms for Gαs ubiquitination2015
- Author(s)
  Koimori T, Nishimura M, Takeda H, Tago K, Kobayashi T, Sawazaki T, Itoh H
- Organizer
  Pontianak International Conference on Advanced Pharmaceutical Sciences (PICAPS) 2015 and the 6th Annual Symposium of Indonesian Society for Cancer Chemoprevention
- Place of Presentation
  Pontianak, Indonesia
- Year and Date
  2015-09-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] 紡錘体形成におけるRic-8とGαiシグナルの役割2015
- Author(s)
  堀部修平, 梶　紀子, 小林　哲夫, 伊東　広
- Organizer
  第67回日本細胞生物学会
- Place of Presentation
  タワーホール船場（東京都江戸川区）
- Year and Date
  2015-06-30
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] Analysis of serotonin signaling mediated through primary cilia2015
- Author(s)
  Dateyama Izumi, Tetsuo Kobayashi, Hiroshi Itoh
- Organizer
  The 4th International Conference on Pharmacy and Advanced Pharmaceutical Sciences
- Place of Presentation
  Yogyakarta, Indonesia
- Year and Date
  2015-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07931
[Presentation] The role of Ric-8A and Gαi signaling in spindle formation2015
- Author(s)
  Horibe S, Kaji N, Kobayashi T, Itoh H
- Organizer
  International Conference on Biosciences (IcoBio)
- Place of Presentation
  Bogor, Indonesia
- Year and Date
  2015-08-06
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] HDAC2 mediates loss of primary cilia in pancreatic ductal adenocarcinoma cells2015
- Author(s)
  Tetsuo Kobayashi, Kosuke Nakazono, Mio Tokuda, Yu Mashima, Brian David Dynlacht, Hiroshi Itoh
- Organizer
  The 2nd International Meeting for Epithelial Tubulology
- Place of Presentation
  Furate Hall, Hokkaido University, Sapporo, Hokkaido
- Year and Date
  2015-08-22
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112712
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析2015
- Author(s)
  小林　哲夫、中薗　昂亮、徳田　澪、馬島　友、伊達山　泉、Brian David Dynlacht、伊東　広
- Organizer
  第6回繊毛研究会
- Place of Presentation
  基礎生物学研究所、岡崎市、愛知県
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PUBLICLY-26112712
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析2015
- Author(s)
  小林　哲夫、中薗　昂亮、徳田　澪、馬島　友、伊達山　泉、Brian David Dynlacht、伊東　広
- Organizer
  第6回繊毛研究会
- Place of Presentation
  基礎生物学研究所、岡崎市、愛知県
- Year and Date
  2015-11-13
- Data Source
  KAKENHI-PUBLICLY-15H01215
[Presentation] Analysis of serotonin signaling mediated through primary cilia2015
- Author(s)
  Dateyama I, Kobayashi T, Itoh H
- Organizer
  The 4th International Conference on Pharmacy and Advanced Pharmaceutical Sciences
- Place of Presentation
  Yogyakarta, Indonesia
- Year and Date
  2015-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] Gαsユビキチン修飾を制御する分子機構の解析2015
- Author(s)
  鯉森貴行, 西村基喜, 竹田浩之, 多胡憲治, 小林　哲夫, 澤崎達也, 伊東　広
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学大会
- Place of Presentation
  神戸ポートアイランド（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] Analysis of serotonin signaling mediated through primary cilia2015
- Author(s)
  Dateyama Izumi, Tetsuo Kobayashi, Hiroshi Itoh
- Organizer
  The 4th International Conference on Pharmacy and Advanced Pharmaceutical Sciences
- Place of Presentation
  Yogyakarta, Indonesia
- Year and Date
  2015-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-26112712
[Presentation] 膵管癌細胞における一次繊毛消失メカニズムの解析2015
- Author(s)
  小林　哲夫、中薗　昂亮、徳田　澪、馬島　友、Brian David Dynlacht、伊東　広
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K07931
[Presentation] 膵管癌細胞における一次繊毛消失メカニズムの解析2015
- Author(s)
  小林　哲夫、中薗　昂亮、徳田　澪、馬島　友、Brian David Dynlacht、伊東　広
- Organizer
  第38回日本分子生物学会
- Place of Presentation
  神戸ポートアイランド、神戸市、兵庫県
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PUBLICLY-15H01215
[Presentation] Molecular mechanism of loss of primary cilia in pancreatic ductal adenocarcinoma cells2014
- Author(s)
  Tetsuo Kobayashi, Kosuke Nakazono, Izumi Dateyama, Brian David Dynlacht, Hiroshi Itoh
- Organizer
  Keystone Symposia -Cilia, Development and Human Disease-
- Place of Presentation
  Granlibakken Resort, Tahoe city, CA, USA
- Data Source
  KAKENHI-PROJECT-25860048
[Presentation] 膵管癌細胞における一次繊毛消失メカニズムの解析2013
- Author(s)
  小林　哲夫、中薗　昂亮、Brian David Dynlacht、伊東　広
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド、兵庫県神戸市
- Data Source
  KAKENHI-PROJECT-25860048
[Presentation] CP110-interacting proteins, Talpid3 and Cep290, play distinct roles in cilia assembly2013
- Author(s)
  Tetsuo Kobayashi, Sehyun Kim, Yu-Chun Lin, Takanari Inoue, Brian David Dynlacht
- Organizer
  第65回日本細胞生物学大会
- Place of Presentation
  ウインクあいち、愛知県名古屋市
- Invited
- Data Source
  KAKENHI-PROJECT-25860048
[Presentation] 膵管細胞における一次繊毛消失メカニズムの解析2013
- Author(s)
  小林哲夫　他
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸、兵庫
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] The Arf-like GTPase ARL-8 is required for lysosome biogenesis in C. elegans2009
- Author(s)
  Nakae I, Fujino T, Kobayashi T, Kikko Y, Harada S, Fukuyama M, Gengyo-Ando K, Mitani S, Kontani K, Katada T
- Organizer
  17th International C.elegans Meeting
- Place of Presentation
  Los Angeles, CA, USA
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-20247011
[Presentation] The Arf-like GTPase ARL-8 is required for lysosome biogenesis in C. elegans2009
- Author(s)
  Nakae I, Fujino T, Kobayashi T, Kikko Y, Harada S, Fukuyama M, Gengyo-, o K, Mitani S, Kontani K, Katada T
- Organizer
  17th International C. elegans Meeting
- Place of Presentation
  Los Angeles, CA, USA
- Year and Date
  2009-06-27
- Data Source
  KAKENHI-PROJECT-17079002
[Presentation] Functional analysis of the Arf-like small GTPase Arl8 in lysosomesシンポジウム「Membrane Traffic and Organellar Functions」2007
- Author(s)
  紺谷圏二、藤野知子、小林哲夫、中江郁青、菊香順史、原田さやか、安藤恵子、三谷昌平、堅田利明
- Organizer
  第30回日本分子生物学会・第80回日本生化学会合同大会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-17079002
[Presentation] Functional analysis of Ar18 GTPase in lysosomes2006
- Author(s)
  Tomoko Fujino, Tetsuo Kobayashi, Isei Nakae, Keiko Gengyo-Ando, Shohei Mitani, Kenji Kontani, Toshiaki Katada
- Organizer
  The International Symposium on Membrane Traffic
- Place of Presentation
  Awajishima, Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18207008
[Presentation] 一次繊毛におけるRab-likeファミリータンパク質群の機能解析
- Author(s)
  太田麗央, 小林哲夫, 伊東広
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] 機能抗体を用いた癌細胞におけるGPR56の機能解析
- Author(s)
  水野憲一, 太田茂之, 小林祐希, 坂口さや香, 伊東広
- Organizer
  第66回日本細胞生物学会
- Place of Presentation
  奈良県新公会堂、奈良県奈良市
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析
- Author(s)
  小林　哲夫、中薗　昂亮、Brian David Dynlacht、伊東　広
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂、奈良県奈良市
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PUBLICLY-26112712
[Presentation] 一次繊毛におけるRab-like ファミリータンパク質群の機能解析
- Author(s)
  太田　麗央、小林　哲夫、伊東　広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25860048
[Presentation] Analysis of molecular mechanism for Gαs ubiquitination
- Author(s)
  Koimori Takayuki, Tetsuo Kobayashi, Hiroshi Itoh
- Organizer
  The 2014 ASCB meeting
- Place of Presentation
  Philadelphia, U.S.A.
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] 一次繊毛を介したセロトニンシグナル伝達機構の解析
- Author(s)
  伊達山泉, 小林哲夫, 伊東広
- Organizer
  第66回日本細胞生物学会
- Place of Presentation
  奈良県新公会堂、奈良県奈良市
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] HDAC2 mediates loss of primary cilia in pancreatic ductal adenocarcinoma cells
- Author(s)
  Tetsuo Kobayashi, Kosuke Nakazono, Mio Tokuda, Brian David Dynlacht, Hiroshi Itoh
- Organizer
  The 2014 ASCB/IFCB Meeting
- Place of Presentation
  Philadelphia convention center, Philadelphia, Pennsylvania, USA
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PUBLICLY-26112712
[Presentation] HDAC2 mediates loss of primary cilia in pancreatic ductal adenocarcinoma cells
- Author(s)
  Tetsuo Kobayashi, Kosuke Nakazono, Mio Tokuda, Brian David Dynlacht, Hiroshi Itoh
- Organizer
  The 2014 ASCB/IFCB Meeting
- Place of Presentation
  Philadelphia convention center, Philadelphia, Pennsylvania, USA
- Year and Date
  2014-12-06 – 2014-12-10
- Data Source
  KAKENHI-PROJECT-25860048
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析
- Author(s)
  中薗　昂亮、小林　哲夫、徳田　澪、Brian David Dynlacht、伊東　広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PUBLICLY-26112712
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析
- Author(s)
  中薗　昂亮、小林　哲夫、徳田　澪、Brian David Dynlacht、伊東　広
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25860048
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析
- Author(s)
  小林　哲夫、中薗　昂亮、Brian David Dynlacht、伊東　広
- Organizer
  第66回日本細胞生物学会大会
- Place of Presentation
  奈良県新公会堂、奈良県奈良市
- Year and Date
  2014-06-11 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-25860048
[Presentation] Gタンパク質共益受容体GPR56の結合分子Leprecan1の解析
- Author(s)
  小坂隆二, 岩崎　剛, 中村陽介, 松田直樹, 多胡憲治, 小林哲夫, 伊東　広
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25293013
[Presentation] 膵管癌細胞における一次繊毛消失機構の解析
- Author(s)
  中薗昴亮, 小林哲夫, 徳田澪, Brian David Dynlacht, 伊東広
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  パシフィコ横浜、神奈川県横浜市
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25293013

1. KONTANI Kenji (30302615)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
2. KATADA Toshiaki (10088859)

# of Collaborated Projects: 5 results

# of Collaborated Products: 19 results
3. FUKUYAMA Masamitsu (20422389)

# of Collaborated Projects: 5 results

# of Collaborated Products: 4 results
4. KAJIHO Hiroaki (70401221)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
5. SAITO Kota (60549632)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. Itoh Hiroshi (10183005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results

Kobayashi Tetsuo 小林 哲夫

KOBAYASHI Tetsuo 小林 哲夫

Research Projects

Research Products

Co-Researchers

乳癌関連線維芽細胞における一次繊毛増加の分子機構と癌に及ぼす影響の解明Principal Investigator

Principal Investigator

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膵管がんにおける一次繊毛消失の分子機構と影響の解明Principal Investigator

Principal Investigator

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Review Section

Research Institution

Molecular mechanism and impact of loss of primary cilia in PDAC cellsPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Molecular mechanism of ciliary vesicle formation in mammalian cellsPrincipal Investigator

Principal Investigator

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一次繊毛局在性GPCRのシグナル制御と輸送メカニズムの解明Principal Investigator

Principal Investigator

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Review Section

Research Institution

膵管癌細胞における一次繊毛消失機構の解明と癌治療への応用Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Analysis of the regulatory mechanisms of G protein-coupled receptor signaling

Principal Investigator

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Regulation of primary cilia formation cycle by Kif24Principal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

Regulation of intracellular vesicle transport by small GTPase cycles

Principal Investigator

Project Period (FY)

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Research Institution

遺伝学的手法による上皮細胞の蛋白質選別輸送の解析

Principal Investigator

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Research Institution

Comprehensive analysis of genes involved in the regulation of subcellular localization of drug transporters

Principal Investigator

Project Period (FY)

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Research Institution

細胞の増殖と分裂に介在する新奇低分子量G蛋白質群の機能解析

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Membrane-Transport Signaling Involving the GTPase Cycle of G proteins

Principal Investigator

Project Period (FY)

Kobayashi Tetsuo 小林哲夫

KOBAYASHI Tetsuo 小林哲夫