ARAYA Natsumi 新谷奈津美

… Alternative Names

新谷奈津美アラヤナツミ

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Researcher Number	80440353
Other IDs
Affiliation (Current)	2025: 聖マリアンナ医科大学, 医学研究科, 助教
Affiliation (based on the past Project Information) *help	2025: 聖マリアンナ医科大学, 医学研究科, 助教 2016 – 2023: 聖マリアンナ医科大学, 医学研究科, 助教 2010 – 2015: 聖マリアンナ医科大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Neurology
Keywords	Principal Investigator HTLV-1 / 神経障害 / HTLV-1関連脊髄症（HAM） / HTLV-1関連脊髄症 / Tax / HAM / IFN-γ / ミクログリア / グリア細胞 / 神経炎症 … More / 中枢神経 / 炎症 / CXCR3 / CXCL10 / HTLV-1関連脊髄症（HAM) / 制御性T細胞 Less

HAM慢性炎症を起点としたミクログリア介在性の神経障害機構の解明Principal Investigator
- Principal Investigator
  
  新谷奈津美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  St. Marianna University School of Medicine
HAMにおける免疫系と神経系の細胞間ダイナミクスによる神経障害機構の解明Principal Investigator
- Principal Investigator
  
  新谷奈津美
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  St. Marianna University School of Medicine
Mechanism of Neuronal Damage by virus-infected cells in HAM/TSP.Principal Investigator
- Principal Investigator
  
  Araya Natsumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  St. Marianna University School of Medicine
Study of inflammatory loop mechanism caused by virus-infected cells in HAM pathogenesis.Principal Investigator
- Principal Investigator
  
  Araya Natsumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  St. Marianna University School of Medicine
Development of abnormal immune system by regulatory T-cell specific HTLV-1 expression in HAM/TSPPrincipal Investigator
- Principal Investigator
  
  Araya Natsumi
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  St. Marianna University School of Medicine
The molecular mechanism in the development of pathogenic T-cell through HTLV-1 in HTLV-1-associated myelopathy(HAM)Principal Investigator
- Principal Investigator
  
  ARAYA Natsumi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurology
- Research Institution
  St. Marianna University School of Medicine

[Book] T-Cell Leukemia2011
- Author(s)
  Sato T., Araya N., Yagishita N., Ando H., Yamano Y.
- Total Pages
  234
- Data Source
  KAKENHI-PROJECT-22790833
[Journal Article] Large-Scale Whole-Genome Analysis of HTLV-1-Associated Myelopathy Identified Hereditary Spastic Paraplegias2024
- Author(s)
  Takao Naoki、Yagishita Naoko、Araya Natsumi、Aratani Satoko、Yamauchi Junji、Takahashi Katsunori、Kunitomo Yasuo、Sato Tomoo、Nakamori Masahiro、Kawai Yosuke、Omae Yosuke、Tokunaga Katsushi、Matsuda Fumihiko、Mitsuhashi Satomi、Yamano Yoshihisa
- Journal Title
  
  Neurology Genetics
  
  Volume: 10 Issue: 1 Pages: 1-5
- DOI
  10.1212/nxg.0000000000200108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K06954, KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-23K24248
[Journal Article] EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy2023
- Author(s)
  Koseki Akihito、Araya Natsumi、Yamagishi Makoto、Yamauchi Junji、Yagishita Naoko、Takao Naoki、Takahashi Katsunori、Kunitomo Yasuo、Honma Daisuke、Araki Kazushi、Uchimaru Kaoru、Sato Tomoo、Yamano Yoshihisa
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 14 Pages: 1175762-1175762
- DOI
  10.3389/fmicb.2023.1175762
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K06954, KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-23K24248
[Journal Article] Long-term safety and efficacy of mogamulizumab (anti-CCR4) for treating virus-associated myelopathy2023
- Author(s)
  Sato T, Yamauchi J, Yagishita N, Araya N, Takao N, Ohta Y, Inoue E, Takahashi M, Yamagishi M, Suzuki Y, Uchimaru K, Matsumoto N, Hasegawa Y, Yamano Y.
- Journal Title
  
  Brain
  
  Volume: in press Issue: 8 Pages: 3181-3191
- DOI
  10.1093/brain/awad139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K06954, KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-23K24248
[Journal Article] Health-related quality of life evaluation using the Short Form-36 in patients with human T-cell leukemia virus type 1-associated myelopathy.2022
- Author(s)
  Kimura M, Yamauchi J, Sato T, Yagishita N, Araya N, Aratani S, Tanabe K, Horibe E, Watanabe T, Coler-Reilly ALG, Nagasaka M, Akasu Y, Kaburagi K, Kikuchi T, Shibata S, Matsumoto H, Koseki A, Inoue S, Takata A, Yamano Y.
- Journal Title
  
  Front. Med(Lausanne)
  
  Volume: 9 Pages: 879379-879379
- DOI
  10.3389/fmed.2022.879379
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-23K24248
[Journal Article] Health-related quality of life evaluation using the Short Form-36 in patients with human T-cell leukemia virus type 1-associated myelopathy.2022
- Author(s)
  Kimura M, Yamauchi J, Sato T, Yagishita N, Araya N, Aratani S, Tanabe K, Horibe E, Watanabe T, Coler-Reilly A, Nagasaka M, Akasu Y, Kaburagi K, Kikuchi T, Shibata S, Matsumoto H, Koseki A, Inoue S, Takata A, Yamano Y.
- Journal Title
  
  Front Med
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08004
[Journal Article] RAISING is a high-performance method for identifying random transgene integration sites.2022
- Author(s)
  Wada Y, Sato T, Hasegawa H, Matsudaira T, Nao N, Coler-Reilly ALG, Tasaka T, Yamauchi S, Okagawa T, Momose H, Tanio M, Kuramitsu M, Sasaki D, Matsumoto N, Yagishita N, Yamauchi J, Araya N, et al.
- Journal Title
  
  Commun Biol
  
  Volume: 5(1) Issue: 1 Pages: 535-535
- DOI
  10.1038/s42003-022-03467-w
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-21K08386, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-22K19232, KAKENHI-PROJECT-22K15420, KAKENHI-PROJECT-23K23768, KAKENHI-PROJECT-23K24233, KAKENHI-PROJECT-23K24248, KAKENHI-PROJECT-22H04923
[Journal Article] Potential Role of HTLV-1 Tax-Specific Cytotoxic T Lymphocytes expressing a Unique T-cell Receptor to Promote Inflammation of the Central Nervous System in Myelopathy Associated with HTLV-1.2022
- Author(s)
  Tanaka Y, Sato T, Yagishita N, Yamauchi J, Araya N, Aratani S, Takahashi K, Kunitomo Y, Nagasaka M, Kanda Y, Uchimaru K, Morio T, Yamano Y.
- Journal Title
  
  Front Immunol
  
  Volume: 13 Pages: 993025-993025
- DOI
  10.3389/fimmu.2022.993025
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07427, KAKENHI-PROJECT-22K07507, KAKENHI-PROJECT-22K07513, KAKENHI-PROJECT-23K24248, KAKENHI-PROJECT-22H04923
[Journal Article] Efficacy of corticosteroid therapy for HTLV-1-associated myelopathy: A randomized controlled trial (HAMLET-P).2022
- Author(s)
  Yamauchi J, Tanabe K, Sato T, Nakagawa M, Matsuura E, Tsuboi Y, Tamaki K, Sakima H, Ishihara S, Ohta Y, Matsumoto N, Kono K, Yagishita N, Araya N, Takahashi K, Kunitomo Y, Nagasaka M, Coler-Reilly ALG, Hasegawa Y, Araujo A, Jacobson S, Grassi MFR, Galvao-Castro B, Bland M, Taylor GP, Martin F, Yamano Y.
- Journal Title
  
  Viruses
  
  Volume: in press Issue: 1 Pages: 136-136
- DOI
  10.3390/v14010136
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-21K07427
[Journal Article] Clinical course of neurogenic bladder dysfunction in human T-cell leukemia virus type-1-associated myelopathy/tropical spastic paraparesis: A nationwide registry study in Japan.2021
- Author(s)
  Iijima N, Yamauchi J, Yagishita N, Araya N, Aratani S, Tanabe K, Sato T, Takata A, Yamano Y.
- Journal Title
  
  Orphanet J Rare Dis
  
  Volume: 16(1) Issue: 1 Pages: 355-355
- DOI
  10.1186/s13023-021-01990-3
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-21K07427
[Journal Article] An update on human T-cell leukemia virus type I (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) focusing on clinical and laboratory biomarkers.2021
- Author(s)
  Yamauchi J, Araya N, Yagishita N, Sata t, Yamano Y.
- Journal Title
  
  Pharmacol Ther
  
  Volume: 218 Pages: 107669-107669
- DOI
  10.1016/j.pharmthera.2020.107669
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-21K07427
[Journal Article] HTLV-1陽性臓器移植のエビデンス・プラクティスギャップに関する全国アンケート調査.2021
- Author(s)
  山内淳司, 新谷奈津美, 八木下尚子, 佐藤知雄, 湯沢賢治, 山野嘉久.
- Journal Title
  
  移植
  
  Volume: 56(4) Pages: 377-387
- NAID
  130008163168
- Data Source
  KAKENHI-PROJECT-19K08004
[Journal Article] Mortality and risk of progression to adult T-cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.2020
- Author(s)
  Nagasaka M, Yamagishi M, Yagishita N, Araya N, Kobayashi S, Makiyama J, Kubokawa M, Yamauchi J, Hasegawa D, Coler-Reilly ALG, Tsutsumi S, Uemura Y, Arai A, Takata A, Inoue E, Hasegawa Y, Watanabe T, Suzuki Y, Uchimaru K, Sato T, Yamano Y.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: in press
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08004
[Journal Article] HTLV-1関連脊髄症（HAM）の病態.2020
- Author(s)
  新谷奈津美, 山野嘉久.
- Journal Title
  
  別冊BIO Clinica 神経疾患と慢性炎症
  
  Volume: 9(2) Pages: 29-33
- Data Source
  KAKENHI-PROJECT-19K08004
[Journal Article] Mortality and risk of progression to adult T-cell leukemia/lymphoma in HTLV-1-associated myelopathy/tropical spastic paraparesis.2020
- Author(s)
  Nagasaka M, Yamagishi M, Yagishita N, Araya N, Kobayashi S, Makiyama J, Kubokawa M, Yamauchi J, Hasegawa D, Coler-Reilly ALG, Tsutsumi S, Uemura Y, Arai A, Takata A, Inoue E, Hasegawa Y, Watanabe T, Suzuki Y, Uchimaru K, Sato T, Yamano Y.
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 117(21) Issue: 21 Pages: 11685-11691
- DOI
  10.1073/pnas.1920346117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-20K08720, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-18K08317
[Journal Article] Creation and validation of a bladder dysfunction symptom score for HTLV-1-associated myelopathy/tropical spastic paraparesis.2020
- Author(s)
  Yamakawa N, Yagishita N, Matsuo T, Yamauchi J, Ueno T, Inoue E, Takata A, Nagasaka M, Araya N, Hasegawa D, Coler-Reilly A, Tsutsumi S, Sato T, Araujo A, Casseb J, Gotuzzo E, Jacobson S, Martin F, Puccioni-Sohler M, Taylor GP, Yamano Y; Japan Clinical Research Group on HAM/TSP.
- Journal Title
  
  Orphanet J Rare Dis
  
  Volume: 15(1) Issue: 1 Pages: 175-175
- DOI
  10.1186/s13023-020-01451-3
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-20K09824, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575
[Journal Article] Immunophenotypic analysis of cerebrospinal fluid reveals concurrent development of ATL in the CNS of a HAM/TSP patient.2020
- Author(s)
  Takeda R, Ishigaki T, Ohno N, Yokoyama K, Kawamata T, Fukuyama T, Araya N, Yamano Y, Uchimaru K, Tojo A.
- Journal Title
  
  Int J Hematol
  
  Volume: 111(6) Issue: 6 Pages: 891-896
- DOI
  10.1007/s12185-019-02815-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-19K16605
[Journal Article] Cerebrospinal Fluid CXCL10 as a Candidate Surrogate Marker for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis.2019
- Author(s)
  Tamaki K, Sato T, Tsugawa J, Fujioka S, Yagishita N, Araya N, Yamauchi J, Coler-Reilly A, Nagasaka M, Hasegawa Y, Yamano Y, Tsuboi Y.
- Journal Title
  
  Front Microbiol
  
  Volume: 10 Pages: 2110-2110
- DOI
  10.3389/fmicb.2019.02110
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575
[Journal Article] Use of cerebrospinal fluid CXCL10 and neopterin as biomarkers in HTLV-1-associated myelopathy/tropical spastic paraparesis treated with steroids2019
- Author(s)
  Yamauchi Junji、Sato Tomoo、Yagishita Naoko、Araya Natsumi、Hasegawa Daisuke、Tsutsumi Shuntaro、Nagasaka Misako、Coler-Reilly Ariella、Inoue Eisuke、Takata Ayako、Hasegawa Yasuhiro、Yamano Yoshihisa
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 91 Issue: 3 Pages: 321-323
- DOI
  10.1136/jnnp-2019-321955
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575
[Journal Article] The Nature of the HTLV-1 Provirus in Naturally Infected Individuals Analyzed by the Viral DNA-Capture-Seq Approach2019
- Author(s)
  Katsuya H, Islam S, Tan, Ito J, Miyazato P, Matsuo, Inada Y, Iwase, Uchiyama Yoshikazu、Hata Hiroyuki、Sato T, Yagishita N, Araya N, Ueno T, Nosaka K, Tokunaga M, Yamagishi M, Watanabe T, Uchimaru K, Fujisawa J-i, Utsunomiya A, Yamano Y, Satou Y
- Journal Title
  
  Cell Reports
  
  Volume: 29 Issue: 3 Pages: 724-735
- DOI
  10.1016/j.celrep.2019.09.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07152, KAKENHI-PROJECT-18K08317, KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-18KK0230, KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-19J01713, KAKENHI-PROJECT-17K09016, KAKENHI-PROJECT-18K08437, KAKENHI-PROJECT-18K16122, KAKENHI-PROJECT-18KK0452, KAKENHI-PROJECT-16H06277
[Journal Article] Real-world clinical course of HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in Japan2019
- Author(s)
  Tsutsumi Shuntaro、Sato Tomoo、Yagishita Naoko、Yamauchi Junji、Araya Natsumi、Hasegawa Daisuke、Nagasaka Misako、Coler-Reilly Ariella L. G.、Inoue Eisuke、Takata Ayako、Yamano Yoshihisa
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 14 Issue: 1 Pages: 61-61
- DOI
  10.1186/s13023-019-1212-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07822, KAKENHI-PROJECT-19K07983, KAKENHI-PROJECT-19K08004, KAKENHI-PROJECT-19K17049, KAKENHI-PROJECT-19H03575
[Journal Article] Proposal of Classification Criteria for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Disease Activity.2018
- Author(s)
  Sato T, Yagishita N, Tamaki K, Inoue E, Hasegawa D, Nagasaka M, Suzuki H, Araya N, Ariella Coler-Reilly, Hasegawa Y, Tsuboi Y, Takata A, Yamano Y.
- Journal Title
  
  Front Microbiol
  
  Volume: 25(9) Pages: 1651-1651
- DOI
  10.3389/fmicb.2018.01651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-16K09701
[Journal Article] HTLV-1関連脊髄症（HAM）の病態・診断・治療.2018
- Author(s)
  山野嘉久、山内淳司、新谷奈津美、八木下尚子、佐藤知雄.
- Journal Title
  
  神経内科
  
  Volume: 89(3) Pages: 297-303
- Data Source
  KAKENHI-PROJECT-16K09701
[Journal Article] Mogamulizumab (Anti-CCR4) in HTLV-1-Associated Myelopathy.2018
- Author(s)
  Sato T, Coler-Reilly ALG, Yagishita N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y, Yamano Y.
- Journal Title
  
  N Engl J Med.
  
  Volume: 378(6) Issue: 6 Pages: 529-538
- DOI
  10.1056/nejmoa1704827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09701, KAKENHI-PROJECT-16K09702, KAKENHI-PROJECT-17K19610, KAKENHI-PROJECT-16H05336, KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-16H06277
[Journal Article] Effectiveness of Daily Prednisolone to Slow Progression of HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis: A Multi-Center Retrospective Cohort Study.2017
- Author(s)
  Coler-Reilly ALG, Sato T, Matsuzaki T, Nakagawa M, Niino M, Nagai M, Nakamura T, Takenouchi N, Araya N, Yagishita N, Inoue E, Yamano Y.
- Journal Title
  
  Neurotherapeutics
  
  Volume: 14(4) Issue: 4 Pages: 1084-1094
- DOI
  10.1007/s13311-017-0533-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09701, KAKENHI-PROJECT-16K09702, KAKENHI-PROJECT-16H05157, KAKENHI-PROJECT-16H05323
[Journal Article] HTLV-1関連脊髄症（HAM）の分子病態と治療.2017
- Author(s)
  新谷奈津美, 山野嘉久.
- Journal Title
  
  血液内科
  
  Volume: 74(3) Pages: 373-379
- Data Source
  KAKENHI-PROJECT-16K09701
[Journal Article] Nation-wide epidemiological study of Japanese patients with rare viral myelopathy using novel registration system (HAM-net).2016
- Author(s)
  Coler-Reilly ALG, Yagishita N, Suzuki H, Sato T, Araya N, Inoue E, Takata A, Yamano Y.
- Journal Title
  
  Orphanet Journal of Rare Diseases
  
  Volume: 11(1) Issue: 1 Pages: 69-69
- DOI
  10.1186/s13023-016-0451-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-16K09701, KAKENHI-PROJECT-16K09702
[Journal Article] Developing novel treatments for HTLV-1-associated myelopathy (HAM) by investigating molecular pathomechanisms2016
- Author(s)
  新谷奈津美, 佐藤知雄, アリエラ・コラライリー, 八木下尚子, 山野嘉久.
- Journal Title
  
  Japanese Journal of Clinical Immunology
  
  Volume: 39 Issue: 3 Pages: 207-212
- DOI
  10.2177/jsci.39.207
- NAID
  130005157506
- ISSN
  0911-4300, 1349-7413
- Language
  Japanese
- Open Access
- Data Source
  KAKENHI-PROJECT-16H05323, KAKENHI-PROJECT-16K09701, KAKENHI-PROJECT-16K09702
[Journal Article] Mogamulizumab, an anti-CCR4 antibody, targets human T-lymphotropic virus type 1-infected CD8+ and CD4+ T cells to treat associated myelopathy.2015
- Author(s)
  Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Ando H, Kunitomo Y, Takahashi K, Tanaka Y, Shibagaki Y, Nishioka K, Nakajima T, Hasegawa Y, Utsunomiya A, Kimura K, Yamano Y.
- Journal Title
  
  J Infect Dis.
  
  Volume: 211 Issue: 2 Pages: 238-48
- DOI
  10.1093/infdis/jiu438
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-221S0001
[Journal Article] The E3 ligase synoviolin controls body weight and mitochondrial biogenesis through negative regulation of PGC-1β.2015
- Author(s)
  Fujita H, Yagishita N, Aratani S, Saito-Fujita T, Morota S, Yamano Y, Hansson MJ, Inazu M, Kokuba H, Sudo K, Sato E, Kawahara K, Nakajima F, Hasegawa D, Higuchi I, Sato T, Araya N, Usui C, Nishioka K, Nakatani Y, Maruyama I, Usui M, Hara N, Uchino H, Elmer E, Nishioka K, Nakajima T.
- Journal Title
  
  EMBO J.
  
  Volume: 34 Issue: 8 Pages: 1042-55
- DOI
  10.15252/embj.201489897
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-26293387, KAKENHI-PROJECT-26461476, KAKENHI-PROJECT-26670479, KAKENHI-PROJECT-26670793, KAKENHI-PROJECT-26461478, KAKENHI-PROJECT-26461961, KAKENHI-PROJECT-15K15091, KAKENHI-PROJECT-25860726, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-15K15667, KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-26293385
[Journal Article] A plasma diagnostic model of human T cell leukemia virus-1 associated myelopathy.2015
- Author(s)
  Ishihara M, Araya N, Sato T, Saichi N, Fujii R, Yamano Y, Sugano S, Ueda K.
- Journal Title
  
  Ann Clin Transl Neurol
  
  Volume: 2(3) Issue: 3 Pages: 231-240
- DOI
  10.1002/acn3.169
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-26710007
[Journal Article] 免疫性神経疾患－基礎・臨床研究の最新知見－.2015
- Author(s)
  山野嘉久、新谷奈津美、八木下尚子、佐藤知雄.
- Journal Title
  
  日本臨牀
  
  Volume: 73（7） Pages: 546-553
- Data Source
  KAKENHI-PROJECT-24790898
[Journal Article] HTLV-1関連脊髄症（HAM）に対する分子標的治療薬開発の現状と将来.2014
- Author(s)
  新谷奈津美, 山野嘉久.
- Journal Title
  
  血液内科
  
  Volume: 68（1） Pages: 30-35
- Data Source
  KAKENHI-PROJECT-24790898
[Journal Article] HTLV-1 induces a Th1-like state in CD4+CCR4+ T cells.2014
- Author(s)
  Araya N, Sato T, Ando H, Tomaru U, Yoshida M, Coler-Reilly A, Yagishita N, Yamauchi J, Hasegawa A, Kannagi M, Hasegawa Y, Takahashi K, Kunitomo Y, Tanaka Y, Nakajima T, Nishioka K, Utsunomiya A, Jacobson S, Yamano Y.
- Journal Title
  
  J Clin Invest.
  
  Volume: 124 Issue: 8 Pages: 3431-42
- DOI
  10.1172/jci75250
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592282, KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-25460489, KAKENHI-PROJECT-25461181, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-221S0001
[Journal Article] Human T-lymphotropic virus type 1感染者における腎移植の影響.2013
- Author(s)
  山内淳司、八木下尚子、安藤仁、佐藤知雄、新谷奈津美、Ariella, Coler-Reilly、今井直彦、中澤龍斗、佐々木秀郎、柴垣有吾、安田隆、力石辰也、木村健二郎、山野嘉久.
- Journal Title
  
  日本臨床腎移植学会雑誌
  
  Volume: 1(1) Pages: 55-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790898
[Journal Article] Preapoptotic protease calpain-2 is frequently suppressed in adult T-cell leukemia2013
- Author(s)
  Ishihara M., Araya N., Sato T., et al.
- Journal Title
  
  Blood
  
  Volume: in press Issue: 21 Pages: 4340-7
- DOI
  10.1182/blood-2012-08-446922
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22680064, KAKENHI-PROJECT-23701090, KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294, KAKENHI-PROJECT-25830126
[Journal Article] CSF CXCL10, CXCL9, and Neopterin as Candidate Prognostic Biomarkers for HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis.2013
- Author(s)
  Sato T., Coler-Reilly A., Utsunomiya A., Araya N., Yagishita N., Ando H., Yamauchi J., Inoue E., Ueno T., Hasegawa Y., Nishioka K., Nakajima T., Jacobson S., Izumo S., Yamano Y.
- Journal Title
  
  PLoS Negl Trop Dis
  
  Volume: 7(10) Issue: 10 Pages: e2479-e2479
- DOI
  10.1371/journal.pntd.0002479
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294
[Journal Article] Positive feedback loop via astrocytes causes chronic inflammation in virus-associated myelopathy.2013
- Author(s)
  Ando H., Sato T., Tomaru U., Yoshida M., Utsunomiya A., Yamauchi J., Araya N., Yagishita N., Coler-Reilly A., Shimizu Y., Yudoh K., Hasegawa Y., Nishioka K., Nakajima T., Jacobson S., Yamano Y.
- Journal Title
  
  Brain
  
  Volume: 136(Pt9) Issue: 9 Pages: 2876-2887
- DOI
  10.1093/brain/awt183
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790898, KAKENHI-PROJECT-25305032, KAKENHI-PROJECT-25460489, KAKENHI-PROJECT-25461181, KAKENHI-PROJECT-25461293, KAKENHI-PROJECT-25461294
[Journal Article] HTLV-1関連脊髄症(HAM)の治療法を確立していくために-その現状と展望-2012
- Author(s)
  山野嘉久、佐藤知雄、安藤仁、新谷奈津美、八木下尚子
- Journal Title
  
  日本臨牀
  
  Volume: 70(4) Pages: 705-713
- Data Source
  KAKENHI-PROJECT-22790833
[Journal Article] Human T-Lymphotropic Virus Type 1 (HTLV-1) and Regulatory T Cells in HTLV-1-Associated Neuroinflammatory Disease.2011
- Author(s)
  Araya N., Sato T., Yagishita N., et al.
- Journal Title
  
  Viruses
  
  Volume: 3 Issue: 9 Pages: 1532-1548
- DOI
  10.3390/v3091532
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833
[Journal Article] Advantage ofhigher-avidity CTL specific for Taxagainst human T-lymphotropic virus-1 infected cells and tumors.2011
- Author(s)
  Kitazono T., Araya N., Yamano Y.,et al.
- Journal Title
  
  Cell Immunol
  
  Volume: 272(1) Issue: 1 Pages: 11-17
- DOI
  10.1016/j.cellimm.2011.10.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833, KAKENHI-PROJECT-221S0001
[Journal Article] Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type1-associated neurological disease.2011
- Author(s)
  Araya N., et al.
- Journal Title
  
  Antivir Ther
  
  Volume: 16(1) Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790833
[Journal Article] HAM専門外来の取り組み2011
- Author(s)
  山野嘉久、佐藤知雄、新谷奈津美、安藤仁、八木下尚子
- Journal Title
  
  神経内科
  
  Volume: 75(4) Pages: 387-392
- Data Source
  KAKENHI-PROJECT-22790833
[Journal Article] Fucoidan therapy decreases the proviral load in patients with human T-lymphotropic virus type1-associated neurological disease2011
- Author(s)
  Araya N., Takahashi K., Sato T., Nakamura T., Sawa C., Hasegawa D., Ando H., Aratani S., Yagishita N., Fujii R., Oka H., Nishioka K., Nakajima T., Mori N., Yamano Y
- Journal Title
  
  Antivir Ther
  
  Volume: 16(1) Pages: 89-98
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790833
[Journal Article] Overexpression of SPACIA1/SAAL1, a new gene that is involved in synoviocyte proliferation, accelerates the progression of synovitis in mice and humans2011
- Author(s)
  佐藤知雄、中島利博, 他11名
- Journal Title
  
  Arthritis Rheum
  
  Volume: 63 Issue: 12 Pages: 3833-3842
- DOI
  10.1002/art.30617
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22591088, KAKENHI-PROJECT-22790833, KAKENHI-PROJECT-23659176
[Journal Article] Human T-lymphotropic virus type 1 (HTLV-1) and innate immunity2011
- Author(s)
  Sato T., Azakami K., Ando H., Araya N., Yamano Y
- Journal Title
  
  Inflammation and Regeneration
  
  Volume: 31 Issue: 1 Pages: 110-115
- DOI
  10.2492/inflammregen.31.110
- NAID
  130004943766
- ISSN
  1880-8190, 1880-9693
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790833
[Journal Article] HTLV-1関連脊髄症(HAM)の病態と治療2011
- Author(s)
  安藤仁、八木下尚子、新谷奈津美、佐藤知雄、山野嘉久
- Journal Title
  
  医療と検査機器・試薬
  
  Volume: 34(4) Pages: 472-477
- Data Source
  KAKENHI-PROJECT-22790833
[Journal Article] Prostaglandin EP2 receptor signalling inhibits the expression of matrix metalloproteinase 13 in human osteoarthritic chondrocytes2011
- Author(s)
  Sato T, Konomi K, Fujii R, Aono H, Aratani S, Yagishita N, Araya N, Yudoh K, Beppu M, Yamano Y, Nishioka K, Nakajima T
- Journal Title
  
  Ann Rheum Dis
  
  Volume: 70 Issue: 1 Pages: 221-22
- DOI
  10.1136/ard.2009.118620
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833, KAKENHI-PROJECT-23659176
[Journal Article] E3 ubiquitin ligase synoviolin is involved in liver fibrogenesis2010
- Author(s)
  Hasegawa D, Fujii R, Yagishita N, Matsumoto N, Aratani S, Izumi T, Azakami K, Nakazawa M, Fujita H, Sato T, Araya N, Koike J, Tadokoro M, Suzuki N, Nagata K, Senoo H, Friedman SL, Nishioka K, Yamano Y, Itoh F, Nakajima T
- Journal Title
  
  PLoS One
  
  Volume: 5 Issue: 10 Pages: e13590-e13590
- DOI
  10.1371/journal.pone.0013590
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20249052, KAKENHI-PROJECT-22590943, KAKENHI-PROJECT-22790833
[Patent] ＨＴＬＶ－１関連脊髄症を治療することに用いるための医薬組成物2017
- Inventor(s)
  荒木一司、山野嘉久、新谷奈津美
- Industrial Property Rights Holder
  荒木一司、山野嘉久、新谷奈津美
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-007887
- Filing Date
  2017-01-19
- Data Source
  KAKENHI-PROJECT-16K09701
[Patent] HTLV-I 関連脊髄症の予防及び/又は治療のための医薬2010
- Inventor(s)
  山野嘉久、佐藤知雄、新谷奈津美
- Industrial Property Rights Holder
  聖マリアンナ医科大学
- Industrial Property Number
  2010-094641
- Filing Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-22790833
[Patent] HTLV-I関連脊髄症の予防及び/又は治療のための医薬2010
- Inventor(s)
  山野嘉久、佐藤知雄、新谷奈津美
- Industrial Property Rights Holder
  聖マリアンナ医科大学
- Filing Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HAM における HTLV-1 感染細胞に対する EZH1/2 二重阻害剤の増殖抑制効果2023
- Author(s)
  小関昭仁, 新谷奈津美, 山岸誠, 山内淳司, 八木下尚子, 鷹尾直誠, 高橋克典, 國友康夫, 本間大輔, 荒木一司, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] HTLV-1関連脊髄症におけるウイルス感染細胞に起因した神経障害機構の解析2023
- Author(s)
  新谷奈津美, 山岸誠, 清原和裕, 浅原尚美, 中島誠, 荒谷聡子, 八木下尚子, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第27回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] オミックス解析によるHTLV-1関連脊髄症に対する新規原因候補遺伝子の探索とMEK阻害剤の有用性に関する非臨床データ2023
- Author(s)
  鷹尾直誠, 永井香帆, 中島誠, 新谷奈津美, 久世裕太, 鈴木穣, 内丸薫, 山岸誠, 山野嘉久.
- Organizer
  第27回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] HTLV-1感染細胞に起因したHAMの神経障害機構2023
- Author(s)
  新谷奈津美, 山岸誠, 清原和裕, 浅原尚美, 中島誠, 荒谷聡子, 八木下尚子, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] HTLV-1 関連脊髄症に対する MEK 阻害剤の有用性に関する非臨床データ2023
- Author(s)
  鷹尾直誠, 永井香帆, 中島誠, 新谷奈津美, 久世裕太, 鈴木穣, 内丸薫, 山岸誠, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] 統合オミックス解析による HTLV-1 関連脊髄症の新規炎症誘導因子の探索2023
- Author(s)
  中島誠, 永井香帆, 鷹尾直誠, 新谷奈津美, 久世裕太, 鈴木穣, 内丸薫, 山岸誠, 山野嘉久.
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] EZH1/2二重阻害剤はHTLV-1関連脊髄症におけるHTLV-1感染細胞の増殖と過剰免疫応答を抑制する2023
- Author(s)
  小関昭仁, 新谷奈津美, 山岸誠, 山内淳司, 八木下尚子, 本間大輔, 荒木一司, 内丸薫, 佐藤知雄, 山野嘉久.
- Organizer
  第27回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] HTLV-1 関連脊髄症(HAM)の神経障害機構の解析.2022
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 鷹尾直誠, 佐藤知雄, 山野嘉久.
- Organizer
  第8回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] Evaluation of quantification method of HTLV-1 proviral load in white blood cells using whole blood.2022
- Author(s)
  Sato T, Yagishita N, Araya N, Yamauchi J, Takahashi K, Kunitomo Y, Hasegawa Y, Higashikuse Y, Miyachi K, Yamano Y.
- Organizer
  20th International Conference on Human Retrovirology: HTLV and Related Viruses(HTLV22), 8 - 11 May 2022, Melbourne, Australia.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] HTLV-1関連脊髄症（HAM）の病態形成機構.2022
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 佐藤知雄, 山野嘉久.
- Organizer
  第63回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] HAMの排尿障害における臨床症状評価と治療効果判定の標準化スケールの確立.2022
- Author(s)
  鷹尾直誠, 佐藤知雄, 山内淳司, 八木下尚子, 新谷奈津美, 荒谷聡子, 山野嘉久.
- Organizer
  第８回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] A randomized controlled trial on corticosteroid therapy for HTLV-1-associated myelopathy/tropical spastic paraparesis in Japan (HAMLET-P trial).2022
- Author(s)
  Yamauchi J, Sato T, Yagishita N, Araya N, Nakagawa M, Matsuura E, Tsuboi Y, Tamaki K, Sakima H, Ishihara S, Araujo A, Jacobson S, Grassi MFR, Galvao-Castro B, Bland M, Taylor GP, Martin F, Yamano Y.
- Organizer
  20th International Conference on Human Retrovirology: HTLV and Related Viruses(HTLV22)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07507
[Presentation] リアルワールドデータにより示されたHAMの排尿障害に対するミラベグロンの有用性.2021
- Author(s)
  飯島直樹, 山内淳司, 髙梨世子, 太刀川慶史, 八木下尚子, 新谷奈津美, 荒谷聡子, 田辺健一郎,　佐藤知雄, 高田礼子, 山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] リアルワールドデータにより示されたHAMの排尿障害に対するミラベグロンの有用性.2021
- Author(s)
  飯島直樹, 山内淳司, 八木下尚子, 新谷奈津美, 荒谷聡子, 田辺健一郎, 佐藤知雄, 高田礼子, 山野嘉久.
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1陽性臓器移植の診療に関する全国調査.2021
- Author(s)
  山内淳司、新谷奈津美、八木下尚子、佐藤知雄、湯沢賢治、山野嘉久.
- Organizer
  第55回日本臨床腎移植学会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] 全血を用いた改変HTLV-1プロウイルス量定量法に関する検討.2021
- Author(s)
  佐藤知雄、八木下尚子、新谷奈津美、荒谷聡子、山内淳司、高橋克典、國友康夫、長谷川由美子、東久世裕太、宮地恵子、佐藤賢文、直亨則、斎藤益満、山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1による神経障害機構.2021
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 佐藤知雄, 山野嘉久.
- Organizer
  第25回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1関連脊髄症（HAM）における神経障害機構の解析.2021
- Author(s)
  新谷奈津美、荒谷聡子、八木下尚子、山内淳司、佐藤知雄、山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1関連脊髄症（HAM)の神経障害機構2021
- Author(s)
  新谷奈津美, 荒谷聡子, 八木下尚子, 山内淳司, 佐藤知雄, 山野嘉久.
- Organizer
  第62回日本神経学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1陽性の臓器移植に関する全国アンケート調査.2021
- Author(s)
  山内淳司、新谷奈津美、八木下尚子、佐藤知雄、湯沢賢治、山野嘉久.
- Organizer
  第7回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HAM診療ガイドラインの活用実態および内容の評価に関する全国調査2020
- Author(s)
  佐藤知雄, 山内淳司, 新谷奈津美, 高橋克典, 國友康夫, 八木下尚子, 山野嘉久.
- Organizer
  第32回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HAM患者における短期の歩行機能変化の指標としての髄液CXCL10およびネオプテリンの有用性2019
- Author(s)
  山内淳司, 佐藤知雄, 八木下尚子, 新谷奈津美, 井上永介, 山野嘉久.
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1関連脊髄症のヒストリカルコントロールとして利用可能な病歴データの収集分析2019
- Author(s)
  佐藤知雄、八木下尚子、山内淳司、堤俊太郎、新谷奈津美、井上永介、高田礼子、山野嘉久.
- Organizer
  第37回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HAM患者レジストリより収集分析されたHAM患者のリアルワールドデータ.2019
- Author(s)
  佐藤知雄、八木下尚子、山内淳司、堤俊太郎、新谷奈津美、井上永介、高田礼子、山野嘉久.
- Organizer
  第31回日本神経免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1感染初期においてTaxが宿主に与える影響の解析2019
- Author(s)
  水池潤、山岸誠、小林誠一郎、中島誠、新谷奈津美、牧山純也、宇都宮與、田中勇悦、渡邉俊樹、山野嘉久、内丸薫.
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] Progress report on a long-term study of anti-CCR4 antibody (mogamulizumab) in patients with HAM/TSP.2019
- Author(s)
  Sato T, Yagishita N, Araya N, Yamauchi J, Inoue E, Matsumoto N, Hasegawa Y, Yamano Y.
- Organizer
  The 19th International Conference on Human Retrovirology: HTLV and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] Transcriptomic and epigenomic characteristics of HTLV-1-infected cells in asymptomatic carriers, HAM/TSP, and ATL.2019
- Author(s)
  Yamagishi M, Kobayashi S, Makiyama J, Araya N, Nakashima M,Iwanaga M, Utsunomiya A, Tanaka Y, Watanabe T, Yamano Y, Uchimaru K.
- Organizer
  The 19th International Conference on Human Retrovirology: HTLV and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HAMの短期歩行機能変化の指標としての髄液CXCL10およびネオプテリンの有用性2019
- Author(s)
  山内淳司, 佐藤知雄, 八木下尚子, 新谷奈津美, 井上永介, 山野嘉久.
- Organizer
  第37回日本神経治療学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HTLV-1感染細胞におけるIFN-JAK1-STAT1経路の機能的意義2019
- Author(s)
  滝澤絵梨菜、山岸誠、石崎伊純、志賀遥菜、中島誠、新谷奈津美、宇都宮與、中村龍文、田中勇悦、山野嘉久、渡邉俊樹、内丸薫.
- Organizer
  第6回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08004
[Presentation] HAM治療薬としての抗CCR4抗体製剤（モガムリズマブ）.2018
- Author(s)
  佐藤知雄、八木下尚子、新谷奈津美、井上永介、古田梨愛、渡邉俊樹、内丸薫、松岡雅雄、松本直樹、長谷川泰弘、山野嘉久.
- Organizer
  第23回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] HTLV-1関連脊髄症に対する抗CCR4抗体製剤（モガムリズマブ）の医師主導治験.2018
- Author(s)
  佐藤知雄、八木下尚子、新谷奈津美、井上永介、古田梨愛、渡邉俊樹、内丸薫、松岡雅雄、松本直樹、長谷川泰弘、山野嘉久.
- Organizer
  第30回日本神経免疫学会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] 腎移植におけるHTLV-1感染症の危険性.2018
- Author(s)
  山内淳司、山野嘉久、佐藤知雄、八木下尚子、新谷奈津美、松岡雅雄、市丸直嗣、錦戸雅春、柴垣有吾、杉谷篤、中村信之、三重野牧子、湯沢賢治.
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] 腎移植患者のHTLV-1関連疾患発症に関する全国調査.2018
- Author(s)
  山内淳司、山野嘉久、佐藤知雄、八木下尚子、新谷奈津美、松岡雅雄、市丸直嗣、錦戸雅春、柴垣有吾、杉谷篤、中村信之、三重野牧子、湯沢賢治.
- Organizer
  第23回日本神経感染症学会総会・学術大会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] HTLV-1陽性臓器移植患者レジストリの構築.2018
- Author(s)
  山内淳司、山野嘉久、佐藤知雄、八木下尚子、新谷奈津美、松岡雅雄、市丸直嗣、錦戸雅春、柴垣有吾、杉谷篤、中村信之、三重野牧子、湯沢賢治.
- Organizer
  第54回日本移植学会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] HAM患者に対する抗CCR4抗体製剤（モガムリズマブ）の安全性と有効性.2018
- Author(s)
  佐藤知雄、八木下尚子、新谷奈津美、井上永介、古田梨愛、渡邉俊樹、内丸薫、松岡雅雄、松本直樹、長谷川泰弘、山野嘉久.
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Development of a New Assay for Quantification of HTLV-1 Proviral DNA2017
- Author(s)
  Higashikuse Yuta, Nagai Go, Araya Natsumi, Yagishita Naoko, Sato Tomoo, Yamano yoshihisa
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] ＨＡＭ患者レジストリを活用した低用量経口プレドニゾロン維持療法の有効性と安全性に関する検討.2017
- Author(s)
  佐藤知雄, 井上永介, 八木下尚子, 新谷奈津美, 長谷川大輔, 高田礼子, 山野嘉久.
- Organizer
  第４回日本ＨＴＬＶ－１学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Phase 1/2a study of Mogamulizumab, an anti-CCR4 monoclonal antibody, in patients with HTLV-1-associated myelopathy (HAM/TSP).2017
- Author(s)
  Yamano Y, Sato T, A. Coler-Reilly, Yanagisawa N, Araya N, Inoue E, Furuta R, Watanabe T, Uchimaru K, Matsuoka M, Matsumoto N, Hasegawa Y.
- Organizer
  XXIII World Congress of Neurology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Prevalence, Incidence, and Evidence of High ATL Risk among HAM/TSP Patients2017
- Author(s)
  Araya Natsumi, Sato Tomoo, Yagishita Naoko, Ariella Coler-Reilly, Uchimaru Kaoru, Yamano Yoshihisa
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] ＨＴＬＶ－１関連脊髄症（ＨＡＭ）の新たな運動障害重症度評価指標の提案.2017
- Author(s)
  八木下尚子, 佐藤知雄, 長谷川大輔, 新谷奈津美, 井上永介, 高田礼子, 山野嘉久.
- Organizer
  第４回日本ＨＴＬＶ－１学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] A New Index Describing Urinary Dysfunction in Patients with Human T-lymphotropic Virus Type 1-associated Myelopathy2017
- Author(s)
  Yamakawa Natsuko, Amano Saaya, Kawakami Hitomi, Yamashita Hitomi, Yagishita Naoko, Araya Natsumi, Sato Tomoo, Takata Ayako, Matsuo Tomohiro, Yamano Yoshihisa
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Daily Prednisolone Slows the Progression of HAM/TSP2017
- Author(s)
  Ariella L. G. Coler-Reilly, Sato Tomoo, Matsuzaki Toshio, Nakagawa Masanori, Niino Masaaki, Nagai Masahiro, Nakamura Tatsufumi, Takenouchi Norihiro, Araya natsumi, Yagishita Naoko, Yamano Yoshihisa
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Progression Patterns of Osame's Motor Disability Score for HAM/TSP Patients2017
- Author(s)
  Inoue Eisuke, Ariella Coler-Reilly, Araya Natsumi, Yagishita Naoko, Sato Tomoo, Takata Ayako, Yamano Yoshihisa
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] 臨床経過とバイオマーカーに基づくＨＡＭの疾患活動性分類基準の提案.2017
- Author(s)
  長谷川大輔, 八木下尚子, 井上永介, 新谷奈津美, 髙田　礼子, 長谷川泰弘, 佐藤知雄, 山野嘉久.
- Organizer
  第４回日本ＨＴＬＶ－１学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Effectiveness of Low-Dose Oral Prednisolone to Treat and Slow Progression of HAM/TSP: A Nationwide Prospective Cohort Study2017
- Author(s)
  Sato Tomoo,Inoue Eisuke,Yagishita Naoko,Araya Natsumi,Takata Ayako,Yamano Yoshihisa
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Patient Satisfaction Survey for HAM-net Registrants2017
- Author(s)
  Suzuki Hiroko,Sato Kentaro,Kikuchi Takayuki,Kimura Miyuna,Arifuku Hirotaka,Komita Midori,Shimada Kanade,Seki Kurumi,Tachibana Marika,Yagishita Naoko,Ariella Coler-Reilly,Sato Tomoo,Araya Natsumi,Ishikawa Miho,Koike Mikako,Saito Yumi,Takata Ayako,Yamano Yoshihisa
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] Comparative Transcriptome Analysis of HTLV-1-infected Cells and ATL Cells2017
- Author(s)
  Yamagishi Makoto, Nakano Kazumi, Fujikawa Dai, Kobayashi Seiichiro, Araya Natsumi, Sato Tomoo, Yagishita Naoko, Iwanaga Masako, Utsunomiya Atae, Tanaka Yuetsu , Yamano Yoshihisa, Watanabe Toshiki, Uchimaru Kaoru
- Organizer
  The 18th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  東京都千代田区〔Grand Arc Hanzomon〕
- Year and Date
  2017-03-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] HAM発症から診断までの期間における納の運動障害重症度の経時推移の解析2016
- Author(s)
  井上永介、Ariella Coler-Reilly、新谷奈津美、八木下尚子、佐藤知雄、高田礼子、山野嘉久
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島県（鹿児島市）〔鹿児島県市町村自治会館〕
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] HAM患者に対する経口ステロイド維持療法の長期的効果2016
- Author(s)
  佐藤知雄、Ariella Coler-Reilly、新谷奈津美、八木下尚子、中村龍文、永井将弘、新野正明、竹ノ内徳博、中川正法、松崎敏男、山野嘉久
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島県（鹿児島市）〔鹿児島県市町村自治会館〕
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] HTLV-1関連脊髄症（HAM）におけるHAS-Flow法を用いたATL発症高危険度患者の予測2016
- Author(s)
  新谷奈津美、佐藤知雄、八木下尚子、高橋克典、内丸薫、山野嘉久
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島県（鹿児島市）〔鹿児島県市町村自治会館〕
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-16K09701
[Presentation] HAM-net national patient registration system reveals details of how Japanese patients with HTLV-1-associated myelopathy/tropical spastic paraparesis progress over time.2015
- Author(s)
  Coler-Reilly A, Yagishita N, Sato T, Araya N, Ishikawa M, Koike M, Saito Y, Suzuki H, Yamano Y, Takata A.
- Organizer
  17th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  Martinique, Frenchi West Indies
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1陽性ドナーから陰性レシピエントへの生体腎移植によるHAMの特徴.2015
- Author(s)
  山内淳司, 佐藤知雄, 八木下尚子, 新谷奈津美, 大勝秀樹, 長谷川泰弘, 力石辰也, 柴垣有吾, 湯沢賢治, 山野嘉久.
- Organizer
  第2回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] 患者レジストリへの介入方法と患者満足度の変化.2015
- Author(s)
  佐藤健太郎, 菊池崇之, 木村未祐奈, 込田みどり, 島田奏, 関来未, 橘茉莉花, 八木下尚子, 佐藤知雄, 新谷奈津美, 石川美穂, 小池美佳子, 齋藤祐美, 鈴木弘子, 高田礼子, 山野嘉久.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1 Tax induces Th1 master regulator T-bet and thus IFN-γ in CD4+CCR4+ T-cells of virus-associated myelopathy patients.2015
- Author(s)
  Araya N, Sato T, Tomaru U, Coler-Reilly A, Yagishita N, Yamauchi J, Hasegawa A, Kannagi M, Akiyama H,Hasegawa Y, Takahashi K, Kunitomo Y, Tanaka Y, Utsunomiya A, Jacobson S, Yamano Y.
- Organizer
  17th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  Martinique, Frenchi West Indies
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1関連脊髄症(HAM)における髄液細胞のケモカイン受容体解析.2015
- Author(s)
  佐藤知雄, 安藤仁, 高橋克典, 國友康夫, Ariella Coler-Reilly, 新谷奈津美, 八木下尚子, 山野嘉久.
- Organizer
  第2回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HAM患者レジストリ「HAMねっと」の経年的患者満足度調査.2015
- Author(s)
  八木下尚子, 鈴木弘子, 石川美穂, 小池美佳子, 齊藤祐美, 新谷奈津美, 佐藤知雄, 高田礼子, 山野嘉久.
- Organizer
  第2回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Humanized anti-CCR4 antibody KW0761 targets HTLV-1-infected CD4+CCR4+ and CD8+CCR4+ T-cells to treat HAM/TSP.2015
- Author(s)
  Yamano Y, Yamauchi J, Coler-Reilly A, Sato T, Araya N, Yagishita N, Kunitomo Y, Takahashi K, Tanaka Y, Akiyama H, Hasegawa Y, Utsunomiya A.
- Organizer
  17th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  Martinique, Frenchi West Indies
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1-Associated Myelopathy in Preoperatively HTLV-1 Negative Recipients after Kidney Transplantation from HTLV-1 Positive Donors.2015
- Author(s)
  Yamauchi J, Sato T, Yagishita N, Araya N, Chikaraishi T, Shibagaki Y, Yamano Y.
- Organizer
  52nd ERA-EDTA Congress
- Place of Presentation
  London, United Kingdom
- Year and Date
  2015-05-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] 希少難病HAMの臨床的有効性評価指標の検討.2015
- Author(s)
  沢辺愛加, 根岸由衣, 野田和里, 平井祐士, 井上永介, 新谷奈津美, 八木下尚子, 佐藤知雄, 山野嘉久.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] 末梢血CD4陽性T細胞を用いた膜プロテオーム解析によるHTLV-1関連疾患に対する新規治療標的の探索.2015
- Author(s)
  石原誠人, 新谷奈津美, 佐藤知雄, 藤井理沙, 最知直美, 宇都宮與, 山野嘉久, 植田幸嗣.
- Organizer
  第2回日本HTLV-1学会学術集会
- Place of Presentation
  東京大学医科学研究所（東京都港区）
- Year and Date
  2015-08-22
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Characteristics of HAM/TSP after kidney transplantation from HTLV-1 positive living donors.2015
- Author(s)
  Kimura M, Yamauchi J, Taisho H, Sato T, Yagishita N, Araya N, Sato K, Kikuchi T, Hasegawa Y, Chikaraishi T, Shibagaki Y, Yamano Y.
- Organizer
  17th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  Martinique, Frenchi West Indies
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Membrane Proteome Profiling to Discover Therapeutic Targets for HTLV-1 Associated Myelopathy.2015
- Author(s)
  Ishihara M, Araya N, Sato T, Saichi N, Fujii R, Yamano Y, Ueda K.
- Organizer
  14th Human Proteome Organization
- Place of Presentation
  Vancouver, BC, Canada
- Year and Date
  2015-09-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1陽性ドナーからの生体腎移植によるHAMの発症率と特徴.2015
- Author(s)
  山野嘉久, 山内淳司, 大勝秀樹, 佐藤知雄, 八木下尚子, 新谷奈津美, 長谷川泰弘, 力石辰也, 柴垣有吾.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] A three-factor plasma diagnostic model of human T -cell leukemia virus-1 associated myelopathy.2015
- Author(s)
  Ishihara M, Araya N, Sato T, Saichi N, Fujii R, Yamano Y, Ueda K.
- Organizer
  17th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  Martinique, Frenchi West Indies
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Evaluation of clinical outcome measures for HAM/TSP.2015
- Author(s)
  Kikuchi T, Sawabe A, Negishi Y, Noda A, Hirai Y, Inoue E, Kimura M, Sato K, Araya N, Yagishita N, Sato T, Yamano Y.
- Organizer
  17th International Conference on Human Retrovirology: HTLV and Related Viruses
- Place of Presentation
  Martinique, Frenchi West Indies
- Year and Date
  2015-06-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HAM患者レジストリ「HAMねっと」を活用した経年的前向き調査.2015
- Author(s)
  木村未祐奈, 佐藤健太郎, 菊池崇之, 八木下尚子, 新谷奈津美, 石川美穂, 小池美佳子, 齋藤祐美, 佐藤知雄, 鈴木弘子, 木村美也子, 高田礼子, 山野嘉久.
- Organizer
  第56回日本神経学会学術大会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2015-05-20
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1陽性ドナーからの生体腎移植によりレシピエントに発症するHAMの特徴.2015
- Author(s)
  山内淳司,　柴垣有吾,　佐藤知雄，八木下尚子，新谷奈津美，山野嘉久, 力石辰也.
- Organizer
  第60回日本透析医学会学術集会・総会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2015-06-26
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] 定量膜プロテオーム解析によるヒト T 細胞性白血病ウイルス1型（HTLV-1）関連疾患に対する新規治療標的の探索.2015
- Author(s)
  石原誠人, 新谷奈津美, 佐藤知雄, 藤井理沙, 最知直美, 宇都宮與, 山野嘉久, 植田幸嗣.
- Organizer
  日本プロテオーム学会2015年会（JHUPO 第13会大会）
- Place of Presentation
  くまもと森都心プラザ（熊本県熊本市）
- Year and Date
  2015-07-23
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] 定量膜プロテオーム解析による成人 T 細胞性白血病に対する治療標的の探索2015
- Author(s)
  石原誠人, 新谷奈津美, 佐藤知雄, 藤井理沙, 最知直美, 宇都宮與, 山野嘉久, 植田幸嗣.
- Organizer
  第74回日本癌学会学術集会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-10-09
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] CXCL10 and neopterin in CSF are candidate prognostic biomarkers for HTLV-1-associated myelopathy/tropical spastic paraparesis2013
- Author(s)
  Yamano Y, Sato T, Ando H, Araya N, Yagishita N, Yamauchi J, Coler-Reilly A, Utsunomiya A, Jacobson S, Izumo S
- Organizer
  16th International conference on human retrovirology: HTLV and related retroviruses
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HAMにおける抗CCR4抗体製剤の有用性に関する検討2013
- Author(s)
  山野嘉久, 山内淳司, 新谷奈津美, 安藤仁, Ariella Color-Reilly, 八木下尚子, 宇都宮與, 佐藤知雄.
- Organizer
  第25回日本神経免疫学会学術集会
- Place of Presentation
  山口県（下関市）〔海峡メッセ下関〕
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Nation-wide epidemiological study in Japan on HTLV-1 associated myelopathy/tropical spastic paraparesis using HAM-net, a novel patient registration system2013
- Author(s)
  Coler-Reilly A, Hashimoto M, Yagishita N, Sato T, Ando H, Yamauchi J, Araya N, Kimura M, Yamano Y, Takata A
- Organizer
  16th International conference on human retrovirology: HTLV and related retroviruses
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Label free quantitative proteome analysis on cerebrospinal fluid to discover severity grade markers for Human T-cell leukemia virus type 1 associated myelopathy/tropic spastic paraparesis (HAM/TSP)2013
- Author(s)
  Makoto Ishihara, Natsumi Araya, Tomoo Sato, Risa Fujii, Ayako Tatsuguchi, Naomi Saichi, Hidewaki Nakagawa, Yoshihisa Yamano, Koji Ueda
- Organizer
  HUPO 2013
- Place of Presentation
  Kanagawa, Japan
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] 脳脊髄液プロテオーム解析によるヒトTリンパ好性ウイルス関連脊髄症(HAM/TSP)に対する重症度診断アルゴリズムの構築2013
- Author(s)
  石原誠人、新谷奈津美、佐藤知雄、山野嘉久、中川英刀、植田幸嗣
- Organizer
  第6回HTLV-1研究会・シンポジウム
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所講堂〕
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HAM患者登録システム（HAMねっと）の構築による疫学調査と満足度調査の概要報告2013
- Author(s)
  山野嘉久, Ariella Coler-Reilly, 八木下尚子, 佐藤知雄, 新谷奈津美, 橋本充代, 木村美也子, 高田礼子.
- Organizer
  第34回日本臨床薬理学会学術総会
- Place of Presentation
  東京都（千代田区）〔東京国際フォーラム〕
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] The “HAM-net” HAM/TSP Patient Registration System and its Applications: A Sampling of Epidemiological Findings in Japan.2013
- Author(s)
  Coler-Reilly A.L.G., Hashimoto M., Yagishita N., Sato T., Ando H., Yamauchi J., Araya N., Kimura M., Yamano Y., and Takata A.
- Organizer
  第6回HTLV-1研究会・シンポジウム
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所講堂〕
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1関連脊髄症（HAM）の治療標的としてのCCR4+CD4+T細胞2013
- Author(s)
  佐藤知雄、新谷奈津美、安藤仁、Ariella Coler-Reilly、山内淳司、八木下尚子、山野嘉久.
- Organizer
  第6回HTLV-1研究会・シンポジウム
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所講堂〕
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Virus-induced CXCL10-CXCR3 positive feedback loop via astrocytes is critical for maintaining chronic inflammatory lesions in HAM/TSP2013
- Author(s)
  Sato T, Ando H, Tomaru U, Yoshida M, Utsunomiya A, Yamauchi J, Araya N, Yagishita N, Coler-Reilly A, Jacobson S, Yamano Y
- Organizer
  16th International conference on human retrovirology: HTLV and related retroviruses
- Place of Presentation
  Montreal, Canada
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] 成人T細胞白血病ウイルス関連疾患における新規治療標的同定を目的とした定量膜プロテオームプロファイリング2013
- Author(s)
  石原誠人、新谷奈津美、佐藤知雄、宇都宮與、中川英刀、山野嘉久、植田幸嗣
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  神奈川県（横浜市）〔パシフィコ横浜〕
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1関連脊髄症(HAM)におけるHTLV-1を介した病原性T細胞発生機構の解析2011
- Author(s)
  新谷奈津美, 他
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京大学弥生講堂(東京都)
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] The molecular mechanism in the plasticity of HTLV-1 infected CD4+CD25+CCR4+T-cells through HTLV-1 in HAM/TSP2011
- Author(s)
  Araya N., Sato T., Utsunomiya A., Ando H., Yagishita N., Kannagi M., Tanaka Y., Yamano Y
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉県千葉市(幕張メッセ)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-1関連脊髄症(HAM)におけるHTLV-1を介した病原性T細胞発生機構の解析2011
- Author(s)
  新谷奈津美、佐藤知雄、安藤仁、八木下尚子、神奈木真理、田中勇悦、宇都宮與、山野嘉久
- Organizer
  第4回HTLV-1研究会・合同班会議
- Place of Presentation
  東京都(東京大学弥生講堂)
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] The molecular mechanism in the plasticity of HTLV-1 infected CD4+CD25+CCR4+ T-cells through HTLV-1 in HAM/TSP2011
- Author(s)
  Araya N., et al
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ(千葉県千葉市)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] 出雲周二HTLV-1関連脊髄症(HAM)の臨床病型:臨床経過と検査所見に基づいた分類2011
- Author(s)
  山野嘉久、佐藤知雄、新谷奈津美、八木下尚子、安藤仁、宇都宮與
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京都(東京大学弥生講堂)
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] Frequency and functional significance ofγδT cells in HTLV-1-infected individuals.(HTLV-1感染者におけるガンマデルタT細胞の頻度および機能的重要性)2011
- Author(s)
  Sato T., Muto M., Araya N., Kojo S., Maekawa R., Utsunomiya A., Seino K., Yamano Y
- Organizer
  第40回日本免疫学会学術集会
- Place of Presentation
  千葉県千葉市(幕張メッセ)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] The plasticity of HTLV-1 infected CD4+CD25+CCR4+ T-cells through HTLV-1 tax in HAM/TSP2011
- Author(s)
  Araya N., et al
- Organizer
  15th International Conference on Human Retrovirology : HTLV and Related Viruses
- Place of Presentation
  Aula Pieter De Somer (Leuven, Belgium)
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] Clinical subtype of HAM/TSP based on clinical course and laboratory findings2011
- Author(s)
  Yamano Y., Sato T., Araya N., Yagishita N., Shimizu Y., Ando H., Utsunomiya A., Izumo S., Jacobson S., Suzuki N
- Organizer
  15th International Conference on Human Retrovirology : HTLV and Related Viruses
- Place of Presentation
  Leuven, Belgium(Aula Pieter De Somer)
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] Possibility ofγδT cell immunotherapy for HTLV-1-infected individuals2011
- Author(s)
  Sato T., Muto M., Araya N., Maekawa R., Suzuki N., Utsunomiya A., Seino K., Yamano Y
- Organizer
  15th International Conference on Human Retrovirology : HTLV and Related Viruses
- Place of Presentation
  Leuven, Belgium(Aula Pieter De Somer)
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-1感染者に適用可能なガンマデルタT細胞療法の開発2011
- Author(s)
  佐藤知雄、武藤真人、新谷奈津美、八木下尚子、前川隆司、宇都宮與、神奈木真理、清野研一郎、山野嘉久
- Organizer
  第4回HTLV-1研究会
- Place of Presentation
  東京都(東京大学弥生講堂)
- Year and Date
  2011-09-19
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] The plasticity of HTLV-1 infected CD4+CD25+CCR4+T-cells through HTLV-1 tax in HAM/TSP2011
- Author(s)
  Araya N., Sato T., Utsunomiya A., Ando H., Yagishita N., Kannagi M., Nakamura T., Tanaka Y., Jacobson S., Yamano Y
- Organizer
  15th International Conference on Human Retrovirology : HTLV and Related Viruses
- Place of Presentation
  Lauderdale, U. S. A
- Year and Date
  2011-06-05
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-1関連脊髄症(HAM)患者でのフコイダン療法によるウイルス量の減少2011
- Author(s)
  山野嘉久、新谷奈津美、佐藤知雄、中村龍文、森直樹、鈴木登
- Organizer
  第52回日本神経学会学術大会
- Place of Presentation
  愛知県名古屋市(名古屋国際会議場)
- Year and Date
  2011-05-20
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HAMにおけるIFN-γ+CD4+CD25+CCR4+病原性T細胞の発生機構とその脊髄炎症病巣へのリクルート機構に関する解析2010
- Author(s)
  山野嘉久、佐藤知雄、新谷奈津美、安藤仁、神奈木真理、田中勇悦、宇都宮與
- Organizer
  第3回HTLV-1研究会・合同班会議
- Place of Presentation
  東京(東京大学医科学研究所)
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-関連脊髄症(HAM)におけるHTLV-1 taxを介したIFN-γ+CD4+CD25+CCR4+病原性T細胞発生機構の解析2010
- Author(s)
  新谷奈津美, 他
- Organizer
  第3回HTLV-1研究会
- Place of Presentation
  東京(東京大学医科学研究所)
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HAMにおける血中sIL-2RとIP-10のバイオマーカーとしての有用性2010
- Author(s)
  山野嘉久、佐藤知雄、新谷奈津美、鈴木登
- Organizer
  HAMにおける血中sIL-2RとIP-10のバイオマーカーとしての有用性
- Place of Presentation
  東京(東京国際フォーラム)
- Year and Date
  2010-05-21
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HLA-A2トランスジェニックマウスをもちいたTax特異的細胞障害性T細胞の解析2010
- Author(s)
  北薗貴子、岡崎貴裕、新谷奈津美、山野嘉久、山田恭暉、田中勇悦、井上誠、尾崎承一
- Organizer
  第3回HTLV-1研究会・合同班会議
- Place of Presentation
  東京(東京大学医科学研究所
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HAMの疾患活動性血中バイオマーカーの同定およびステロイドの長期予後改善効果に関する検討2010
- Author(s)
  佐藤知雄、新谷奈津美、安藤仁、山野嘉久
- Organizer
  第3回HTLV-1研究会・合同班会議
- Place of Presentation
  東京(東京大学医科学研究所)
- Year and Date
  2010-08-29
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-1 promotes the plasticity of HTLV-1 infected T-cells through the regulation of T-bet transcriptional activation in HAM/TSP2010
- Author(s)
  Araya N., Sato T., Utsunomiya A., Jacobson S. Yamano Y
- Organizer
  Viruses, Genes and Cancer 2010
- Place of Presentation
  Venezia, Italy(Palazzo Cavalli Franchetti)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-関連脊髄症(HAM)におけるIFN-γ+CD4+CD25+CCR4+病原性T細胞発生の分子機構解析2010
- Author(s)
  新谷奈津美, 他
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  神戸(神戸国際会議場)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-関連脊髄症(HAM)におけるHTLV-1 taxを介したIFN-γ+CD4+CD25+CCR4+病原性T細胞発生機構の解析2010
- Author(s)
  新谷奈津美、佐藤知雄、神奈木真理、田中勇悦、宇都宮與、山野嘉久
- Organizer
  第3回HTLV-1研究会・合同班会議
- Place of Presentation
  東京(東京大学医科学研究所)
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-1 promotes the plasticity of HTLV-1 infected T-cells through the regulation of T-bet transcriptional activation in HAM/TSP.2010
- Author(s)
  Araya N., et al.
- Organizer
  Viruses, Genes and Cancer 2010
- Place of Presentation
  Venezia, Italy (Palazzo Cavalli Franchetti)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HTLV-関連脊髄症(HAM)におけるIFN-γ+CD4+CD25+CCR4+病原性T細胞発生の分子機構解析2010
- Author(s)
  新谷奈津美、佐藤知雄、安藤仁、宇都宮與、山野嘉久
- Organizer
  第33回日本分子生物学会年会
- Place of Presentation
  庫県神戸市(神戸国際会議場)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] The plasma levels of soluble IL-2 receptor and CXCL10 are useful indicators for disease activity in patients with HAM/TSP2010
- Author(s)
  Sato T., Araya N., Suzuki N., Yamano Y
- Organizer
  Viruses, Genes and Cancer 2010
- Place of Presentation
  Venezia, Italy(Palazzo Cavalli Franchetti)
- Year and Date
  2010-10-01
- Data Source
  KAKENHI-PROJECT-22790833
[Presentation] HAMにおける抗CCR4抗体療法の有用性およびCCR4+CD8+T細胞の異常に関する検討.
- Author(s)
  山内淳司, 新谷奈津美, 安藤仁, Ariella Coler-Reilly, 國友康夫, 高橋克典, 八木下尚子, 佐藤知雄, 宇都宮與, 山野嘉久.
- Organizer
  第19回日本神経感染症学会総会学術集会・第26回日本神経免疫学会学術集会合同学術集会
- Place of Presentation
  石川県（金沢市）〔金沢歌劇座〕
- Year and Date
  2014-09-04 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HAMにおけるTh1様異常T細胞の発生機構および病態への関与.
- Author(s)
  佐藤知雄、新谷奈津美、安藤仁、山内淳司、國友康夫、高橋克典、斎藤祐美、石川美穂、八木下尚子、山野嘉久.
- Organizer
  第19回日本神経感染症学会総会学術集会・第26回日本神経免疫学会学術集会合同学術集会
- Place of Presentation
  石川県（金沢市）〔金沢歌劇座〕
- Year and Date
  2014-09-04 – 2014-09-06
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1によるHTLV-1関連脊髄症（HAM）病原性T細胞の発生機構の解析.
- Author(s)
  新谷奈津美, 佐藤知雄, 安藤仁, 外丸詩野, Ariella Coler-Reilly, 八木下尚子, 山内淳司, 長谷川温彦, 神奈木真理, 田中勇悦, 宇都宮與, 山野嘉久.
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所〕
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HAM患者登録システム「HAMねっと」を用いた疫学的解析.
- Author(s)
  山野嘉久, 木村美也子, 八木下尚子, 鈴木弘子, 石川美穂, 小池美佳子, 齊藤祐美, 新谷奈津美, 佐藤知雄, 高田礼子.
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所〕
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] Quantitative membrane proteome profiling to discover therapeutic targets for adult T-cell leukemia (ATL).
- Author(s)
  Ishihara M, Araya N, Sato T, Fujii R, Tatsuguchi A, Saichi N, Nakagawa H, Yamano Y, Ueda K.
- Organizer
  AACR Annual Meeting 2014
- Place of Presentation
  San Diego, USA.
- Year and Date
  2014-04-05 – 2014-04-09
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] CD4陽性T細胞を用いた膜プロテオーム解析によるHTLV-1関連脊髄症に対する新規治療標的分子の探索.
- Author(s)
  石原誠人, 新谷奈津美,　佐藤知雄,　藤井理沙, 最知直美, 宇都宮與, 山野嘉久, 菅野純夫,　植田幸嗣.
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所〕
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1関連脊髄症（HAM）の臨床的評価指標の有用性に関する検討.
- Author(s)
  佐藤知雄, 井上永介, 新谷奈津美, 高橋克典, 國友康夫, Ariella Coler-Reilly, 山内淳司,　八木下尚子,　山野嘉久.
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所〕
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HAMにおける抗CCR4抗体療法の有用性およびCCR4+CD8+T細胞の異常に関する検討.
- Author(s)
  山内淳司, 新谷奈津美,　安藤仁, 國友康夫, 高橋克典, Ariella Coler-Reilly, 八木下尚子,　佐藤知雄, 宇都宮與, 山野嘉久.
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所〕
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24790898
[Presentation] HTLV-1関連脊髄症(HAM)患者登録システム「HAMねっと」の患者満足度調査.
- Author(s)
  八木下尚子, 有福厚孝, 菊池崇之, 木村未祐奈, 佐藤健太郎, 石川美穂, 鈴木弘子, 小池美佳子, 齊藤祐美, 新谷奈津美, 佐藤知雄, 木村美也子, 高田礼子, 山野嘉久.
- Organizer
  第1回日本HTLV-1学会学術集会
- Place of Presentation
  東京都（港区）〔東京大学医科学研究所〕
- Year and Date
  2014-08-22 – 2014-08-24
- Data Source
  KAKENHI-PROJECT-24790898

1. Takahashi Katsunori

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
2. YAMANO Yoshihisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
3. SATO Tomoo

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
4. KAMI Masahiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. SATOU Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 中島利博

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
7. 八木下尚子

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
8. 荒谷聡子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
9. 佐藤聡美

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
10. 井上永介

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
11. 藤沢順一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 山岸誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ARAYA Natsumi 新谷 奈津美

新谷 奈津美 アラヤ ナツミ

Research Projects

Research Products

Co-Researchers

HAM慢性炎症を起点としたミクログリア介在性の神経障害機構の解明Principal Investigator

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HAMにおける免疫系と神経系の細胞間ダイナミクスによる神経障害機構の解明Principal Investigator

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Mechanism of Neuronal Damage by virus-infected cells in HAM/TSP.Principal Investigator

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Study of inflammatory loop mechanism caused by virus-infected cells in HAM pathogenesis.Principal Investigator

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Development of abnormal immune system by regulatory T-cell specific HTLV-1 expression in HAM/TSPPrincipal Investigator

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The molecular mechanism in the development of pathogenic T-cell through HTLV-1 in HTLV-1-associated myelopathy(HAM)Principal Investigator

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[Book] T-Cell Leukemia2011

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[Journal Article] Large-Scale Whole-Genome Analysis of HTLV-1-Associated Myelopathy Identified Hereditary Spastic Paraplegias2024

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[Journal Article] EZH1/2 dual inhibitors suppress HTLV-1-infected cell proliferation and hyperimmune response in HTLV-1-associated myelopathy2023

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[Journal Article] Long-term safety and efficacy of mogamulizumab (anti-CCR4) for treating virus-associated myelopathy2023

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[Journal Article] Health-related quality of life evaluation using the Short Form-36 in patients with human T-cell leukemia virus type 1-associated myelopathy.2022

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[Journal Article] Health-related quality of life evaluation using the Short Form-36 in patients with human T-cell leukemia virus type 1-associated myelopathy.2022

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[Journal Article] RAISING is a high-performance method for identifying random transgene integration sites.2022

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[Journal Article] Potential Role of HTLV-1 Tax-Specific Cytotoxic T Lymphocytes expressing a Unique T-cell Receptor to Promote Inflammation of the Central Nervous System in Myelopathy Associated with HTLV-1.2022

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[Journal Article] Efficacy of corticosteroid therapy for HTLV-1-associated myelopathy: A randomized controlled trial (HAMLET-P).2022

ARAYA Natsumi 新谷奈津美

新谷奈津美アラヤナツミ