Suzuki Shiho 鈴木志穂

… Alternative Names

SUZUKI Shiho 鈴木志穂

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Researcher Number	80444074
Other IDs
Affiliation (based on the past Project Information) *help	2022: 北海道大学, 歯学研究院, 助教 2016 – 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 助教 2015: 東京大学, 医科学研究所, 特任助教 2014: 東京大学, 医科学研究所, 特任研究員 2008: The University of Tokyo, 医科学研究所, 特任研究員 2007: The University of Tokyo, 医科学研究所, 特別孝育研究員
Review Section/Research Field	Principal Investigator Bacteriology (including mycology) / Basic Section 57020:Oral pathobiological science-related / Bacteriology (including Mycology)
Keywords	Principal Investigator インフラマソーム / 赤痢菌 / 抗炎症性 / 歯周病菌 / 免疫学 / 感染症 / 細菌 / Inflammasome / 炎症応答 / マクロファージ … More / 炎症 / ユビキチン化 / cIAP / E3ユビキチンリガーゼ / 自己炎症性疾患 / Pyroptosis / NLRC4 / NAIP / inflammasome / 病原細菌-宿主間相互作用 / 細胞死 / エフェクター / 感染免疫 Less

歯周病菌P.intermediaがもつインフラマソーム阻害分子の特定と創薬展開Principal Investigator
- Principal Investigator
  
  鈴木志穂
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Hokkaido University
Regulation of inflammasomes mediated by the E3 ubiquitin ligasePrincipal Investigator
- Principal Investigator
  
  Suzuki Shiho
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Tokyo Medical and Dental University
Recognition machinery of Shigella by NAIPs.Principal Investigator
- Principal Investigator
  
  Suzuki Shiho
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  The University of Tokyo
Molecular analysis of macrophage cell death induced by shigella infection.Principal Investigator
- Principal Investigator
  
  SUZUKI Shiho
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Bacteriology (including Mycology)
- Research Institution
  The University of Tokyo

All 2020 2019 2018 2017 2016 2015 2014 2009 Other

All Journal Article Presentation

[Journal Article] 細菌感染制御 Porphyromonas gingivalisによる炎症誘導機構2019
- Author(s)
  岡野徳壽, 芦田浩, 鈴木志穂, 鈴木敏彦
- Journal Title
  
  口腔病学会雑誌
  
  Volume: 86 Pages: 47-47
- Data Source
  KAKENHI-PROJECT-16K08772
[Journal Article] Inflammasome activation induced by perfringolysin O of Clostridium perfringens and its involvement in the progression of gas gangrene.2019
- Author(s)
  Yamamura K, Ashida H, Okano T, Kinoshita-Daitoku R, Suzuki S, Ohtani K, Hamagaki M, Ikeda T, Suzuki T.
- Journal Title
  
  Frontiers Microbiology
  
  Volume: 10 Pages: 2406-2406
- DOI
  10.3389/fmicb.2019.02406
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03467, KAKENHI-PROJECT-16K08772
[Journal Article] Shigella hijacks the glomulin?cIAPs?inflammasome axis to promote inflammation2018
- Author(s)
  Suzuki Shiho、Suzuki Toshihiko、Mimuro Hitomi、Mizushima Tsunehiro、Sasakawa Chihiro
- Journal Title
  
  EMBO Rep
  
  Volume: 19 Issue: 1 Pages: 89-101
- DOI
  10.15252/embr.201643841
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K14700, KAKENHI-PROJECT-17K19551, KAKENHI-PROJECT-15H04341, KAKENHI-PROJECT-15H04730, KAKENHI-PROJECT-16K08772
[Journal Article] Porphyromonas gingivalis triggers NLRP3-mediated inflammasome activation of macrophages in a bacterial gingipains-independent manner.2018
- Author(s)
  Tokuju Okano, Hiroshi Ashida, Shiho Suzuki, Mikio Shoji, Koji Nakayama, Toshihiko Suzuki,
- Journal Title
  
  Eur. J. Immunol.
  
  Volume: 48 Issue: 12 Pages: 1965-1974
- DOI
  10.1002/eji.201847658
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08772, KAKENHI-PROJECT-16H05504, KAKENHI-PROJECT-16K11451, KAKENHI-PROJECT-16H05186
[Journal Article] CIAP1、CIAP2、XIAPの機能について2018
- Author(s)
  後藤健太, 鈴木志穂, 鈴木敏彦, 山城哲
- Journal Title
  
  琉球医学会誌
  
  Volume: 37 Pages: 118-118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08772
[Journal Article] 赤痢菌が分泌するeffectorタンパクOspD3の解明2018
- Author(s)
  上野理佐子, 芦田浩, 鈴木志穂, 鈴木敏彦, 山城哲
- Journal Title
  
  琉球医学会誌
  
  Volume: 37 Pages: 119-119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08772
[Journal Article] 病原細菌によるインフラマソーム制御戦略2017
- Author(s)
  芦田浩・鈴木志穂・鈴木敏彦
- Journal Title
  
  細胞
  
  Volume: 49 Pages: 695-699
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K08772
[Journal Article] 赤痢菌の感染機構と宿主免疫からの回避の手口　Infection system by Shigella and their tactics for evasion against host immune responses2016
- Author(s)
  鈴木志穂、鈴木敏彦
- Journal Title
  
  化学療法の領域
  
  Volume: 32 Pages: 37-45
- Data Source
  KAKENHI-PROJECT-16K08772
[Journal Article] Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkc δ.2014
- Author(s)
  Suzuki S, Franchi L, He Y, Muioz-Planillo R, Mimuro H, Suzuki T, Sasakawa C, Nunez G.
- Journal Title
  
  PLoS Pathog.
  
  Volume: 10 Issue: 2 Pages: e1003926-e1003926
- DOI
  10.1371/journal.ppat.1003926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23000012, KAKENHI-PROJECT-23390102, KAKENHI-PROJECT-23390106, KAKENHI-PROJECT-24659201, KAKENHI-PROJECT-26860283
[Journal Article] Shigella IpaH7.8 E3 ligase targets glomulin and activates inflammasomes to demolish macrophages2014
- Author(s)
  Suzuki S et.al
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: 111 Issue: 40
- DOI
  10.1073/pnas.1324021111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03405, KAKENHI-PROJECT-23000012, KAKENHI-PUBLICLY-25112506, KAKENHI-PUBLICLY-25121711, KAKENHI-PROJECT-25460527, KAKENHI-PROJECT-25460555, KAKENHI-PROJECT-26293095, KAKENHI-PROJECT-26860283
[Presentation] 歯周病菌Prevotella intermediaの感染がインフラマソーム活性化に与える影響の解析2020
- Author(s)
  鈴木志穂
- Organizer
  東京医科歯科大学最先端口腔科学研究推進プロジェクトバランス(口腔免疫)ユニット若手研究者ワークショップ
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] 病原細菌の感染戦略とインフラマソーム－歯学研究における今後の展開－2020
- Author(s)
  鈴木志穂
- Organizer
  北海道大学大学院歯学研究院　歯学研究セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] GLMN-cIAP1/2 axis controls inflammasome activation in response to bacterial infection2019
- Author(s)
  鈴木志穂、鈴木敏彦、笹川千尋
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] インフラマソーム活性制御因子の探索とその作用機序2019
- Author(s)
  鈴木志穂
- Organizer
  第10回加藤記念研究助成交流会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] Hypoxia induces enhancement of inflammasome activation by P. gingivalis infection2019
- Author(s)
  岡野徳壽, 鈴木志穂, 庄子幹郎, 中山浩次, 鈴木敏彦
- Organizer
  第92回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] GLMN-cIAP1/2 axis controls inflammasome activation in response to bacterial infection2019
- Author(s)
  鈴木志穂、鈴木敏彦、笹川千尋
- Organizer
  第92回日本細菌学会総会、2019年4月23-24日、札幌コンベンションセンター
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] 細菌感染時におけるインフラマソーム活性化の制御メカニズム2018
- Author(s)
  鈴木志穂
- Organizer
  東京大学医科学研究所共同研究拠点成果報告会
- Invited
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] Cellular inhibitor of apoptosis protein 1 and 2 are important for the inflammasome activation2018
- Author(s)
  Shiho Suzuki, Toshihiko Suzuki
- Organizer
  第47回日本免疫学会、2018年12月10日、福岡コンベンションセンター
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] IAP family members are involved in inflammasome activation in response to bacterial infection2018
- Author(s)
  鈴木志穂、鈴木敏彦、三室仁美、笹川千尋
- Organizer
  第91回日本細菌学会総会
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] IAP family members are involved in inflammasome activation in response to bacterial infection.2018
- Author(s)
  鈴木志穂、鈴木敏彦、三室仁美、笹川千尋
- Organizer
  第91回日本細菌学会総会、2018年3月27-28日、福岡コンベンションセンター
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] Identification and analysis of inflammasome regulators involved in inflammasome activation in response to bacterial infection2018
- Author(s)
  Shiho Suzuki, Toshihiko Suzuki, Chihiro Sasakawa
- Organizer
  The 17th Awaji International Forum on Infection and Immunity, Awaji Yumebutai International Conference Center
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] Characterization of macrophage cell death caused by Shigella infection2017
- Author(s)
  鈴木志穂、鈴木敏彦
- Organizer
  第90回日本細菌学会総会、選抜ワークショップ
- Place of Presentation
  仙台国際センター(宮城県・仙台市)
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] インフラマソーム制御因子を標的とした新規免疫賦活剤開発のための基礎研究2017
- Author(s)
  鈴木志穂
- Organizer
  加藤バイオサイエンス研究助成贈呈式
- Place of Presentation
  如水会館（東京都・千代田区）
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] The microbial-host interactions that drive the activation of the Nlrc4 inflammasome in Shigella-infected macrophages2017
- Author(s)
  Shiho Suzuki, Toshihiko Suzuki
- Organizer
  The 46th annual meeting of the japanese society of immunology
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] 細菌感染におけるインフラマソーム活性化2016
- Author(s)
  鈴木志穂
- Organizer
  第98回日本細菌学会関東支部総会若手ワークショップ
- Place of Presentation
  北里大学薬学部コンベンションホール(東京都・港区)
- Invited
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] 細菌感染によるインフラマゾームの活性化機構2016
- Author(s)
  鈴木志穂
- Organizer
  第９９回日本細菌学会関東支部総会
- Place of Presentation
  北里大学薬学部コンベンションホール（東京都港区）
- Year and Date
  2016-10-07
- Invited
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] GLMNは細菌感染におけるinflammasome活性化のnegative regulatorである2016
- Author(s)
  鈴木志穂, 鈴木敏彦, 三室仁美, 笹川千尋
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪府大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] GLMN is functionally involved in inflammasome activation2016
- Author(s)
  Shiho Suzuki, Toshihiko Suzuki
- Organizer
  第45回日本免疫学会ワークショップ
- Place of Presentation
  沖縄コンベンションセンター(沖縄県・宜野湾市)
- Data Source
  KAKENHI-PROJECT-16K08772
[Presentation] Shigella deploy multiple systems to modulate host innate immune responses2015
- Author(s)
  Hiroshi Ashida, Shiho Suzuki, Hitomi Mimuro and Chihiro Sasakawa
- Organizer
  the Cold Spring Harbor Asia conference on Bacterial Infection and Host Defense
- Place of Presentation
  Suzhou, China
- Year and Date
  2015-11-02
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] 赤痢菌感染におけるinflammasome活性化2015
- Author(s)
  鈴木志穂
- Organizer
  東京大学医科学研究所学友会セミナー
- Place of Presentation
  東京大学医科学研究所 (東京都・港区)
- Year and Date
  2015-01-08
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates Inflammasomes2015
- Author(s)
  Shiho Suzuki, Hitomi Mimuro, Michinaga Ogawa, Hiroshi Ashida, Masato Suzuki, Takahito Sanada, Chihiro Sasakawa
- Organizer
  The 14th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin and activates Inflammasomes, (oral presentation, selected from poster applicants)2015
- Author(s)
  Shiho Suzuki
- Organizer
  The 14th Awaji International Forum on Infection and Immunity
- Place of Presentation
  淡路夢舞台国際会議場（兵庫県淡路市）
- Year and Date
  2015-09-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] 病原細菌の感染機構および宿主免疫応答の解析2014
- Author(s)
  鈴木志穂
- Organizer
  公益財団法人アステラス病態代謝研究会研究報告会
- Place of Presentation
  日本工業倶楽部（東京都・千代田区）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] 赤痢菌感染におけるNlrc4 inflammasome活性化の機構2014
- Author(s)
  鈴木志穂、三室仁美、笹川千尋、Gabriel Nunez
- Organizer
  第97回日本細菌学会関東支部総会
- Place of Presentation
  東京ドームホテル（東京都・文京区）
- Year and Date
  2014-10-30
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] Shigella Type Ⅲ Secretion protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation2014
- Author(s)
  Shiho Suzuki, Luigi Franchi, Yuan He, Hitomi Mimuro, Chihiro Sasakawa, Gabriel Nunez
- Organizer
  日米コレラ部会（日米医学協力研究会コレラ・細菌性腸管感染症専門部会）日本側総会
- Place of Presentation
  京都大学稲森財団記念館(京都府・京都市)
- Year and Date
  2014-08-07
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] 赤痢菌のtypeIIIエフェクターIpaH7.8によるマクロファージ細胞死誘導2009
- Author(s)
  鈴木, 志穂
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19790315
[Presentation] 赤痢菌のtype IIIエフェクターIpaH7.8によるマクロファージ細胞死誘導2009
- Author(s)
  鈴木志穂, 笹川千尋
- Organizer
  第82回日本細菌学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2009-03-12
- Data Source
  KAKENHI-PROJECT-19790315
[Presentation] Shigella MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation
- Author(s)
  Shiho Suzuki, Hitomi Mimuro, Chihiro Sasakawa, Gabriel Nunez
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜 (神奈川県・横浜市)
- Year and Date
  2014-11-15 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] Shigella type III secretion protein Mxil is recognized by Naip2 to induce Nlrc4 inflammasome activation
- Author(s)
  Shiho Suzuki
- Organizer
  49th U.S.-Japan Conference on Cholera and Other Enteric Bacterial Infections
- Place of Presentation
  Gainesville, FL (USA)
- Year and Date
  2015-01-14 – 2015-01-16
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] Shigella Type III Secretion Protein MxiI Is Recognized by Naip2 to Induce Nlrc4 Inflammasome Activation
- Author(s)
  Shiho Suzuki, Luigi Franchi, Yuan He, Hitomi Mimuro, Chihiro Sasakawa, Gabriel Nunez
- Organizer
  第13回あわじしま感染症・免疫フォーラム in 奈良
- Place of Presentation
  奈良県新公会堂（奈良県・奈良市）
- Year and Date
  2014-09-23 – 2014-09-26
- Data Source
  KAKENHI-PROJECT-26860283
[Presentation] Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin to activate inflammasomes
- Author(s)
  鈴木志穂、三室仁美、小川道永、芦田浩、鈴木仁人、真田貴人、笹川千尋
- Organizer
  第88回日本細菌学会総会
- Place of Presentation
  長良川国際会議場 (岐阜県・岐阜市)
- Year and Date
  2015-03-27 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-26860283

1. 笹川千尋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 水島恒裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 鈴木敏彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Suzuki Shiho 鈴木 志穂

SUZUKI Shiho 鈴木 志穂

Research Projects

Research Products

Co-Researchers

歯周病菌P.intermediaがもつインフラマソーム阻害分子の特定と創薬展開Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of inflammasomes mediated by the E3 ubiquitin ligasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Recognition machinery of Shigella by NAIPs.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of macrophage cell death induced by shigella infection.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] 細菌感染制御 Porphyromonas gingivalisによる炎症誘導機構2019

Author(s)

Journal Title

Data Source

[Journal Article] Inflammasome activation induced by perfringolysin O of Clostridium perfringens and its involvement in the progression of gas gangrene.2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shigella hijacks the glomulin?cIAPs?inflammasome axis to promote inflammation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Porphyromonas gingivalis triggers NLRP3-mediated inflammasome activation of macrophages in a bacterial gingipains-independent manner.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CIAP1、CIAP2、XIAPの機能について2018

Author(s)

Journal Title

Data Source

[Journal Article] 赤痢菌が分泌するeffectorタンパクOspD3の解明2018

Author(s)

Journal Title

Data Source

[Journal Article] 病原細菌によるインフラマソーム制御戦略2017

Author(s)

Journal Title

Data Source

[Journal Article] 赤痢菌の感染機構と宿主免疫からの回避の手口 Infection system by Shigella and their tactics for evasion against host immune responses2016

Author(s)

Journal Title

Data Source

[Journal Article] Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkc δ.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Shigella IpaH7.8 E3 ligase targets glomulin and activates inflammasomes to demolish macrophages2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] 歯周病菌Prevotella intermediaの感染がインフラマソーム活性化に与える影響の解析2020

Author(s)

Organizer

Data Source

[Presentation] 病原細菌の感染戦略とインフラマソーム －歯学研究における今後の展開－2020

Author(s)

Suzuki Shiho 鈴木志穂

SUZUKI Shiho 鈴木志穂

[Journal Article] 赤痢菌の感染機構と宿主免疫からの回避の手口　Infection system by Shigella and their tactics for evasion against host immune responses2016

[Presentation] 病原細菌の感染戦略とインフラマソーム－歯学研究における今後の展開－2020