Usami Yu 宇佐美悠

… Alternative Names

Researcher Number	80444579
Other IDs
Affiliation (Current)	2022: 大阪大学, 大学院歯学研究科, 講師
Affiliation (based on the past Project Information) *help	2017 – 2021: 大阪大学, 歯学研究科, 講師 2010 – 2015: 大阪大学, 歯学部附属病院, 助教
Review Section/Research Field	Principal Investigator Morphological basic dentistry / Basic Section 57020:Oral pathobiological science-related Except Principal Investigator Morphological basic dentistry / Medium-sized Section 57:Oral science and related fields / Pathobiological dentistry/Dental radiology / Orthodontics/Pediatric dentistry / Basic Section 57070:Developmental dentistry-related / Basic Section 57020:Oral pathobiological science-related
Keywords	Principal Investigator 口腔病理学 / 口腔癌 / 癌微小環境 / 扁平上皮癌 / マクロファージ / 口腔扁平上皮癌 / 舌癌 / 化学発癌 / 浸潤 / 転移 … More Except Principal Investigator 線維性骨異形成症 / 骨細胞 / リン酸化 / Fam20C / 骨髄間質細胞 / マウスモデル / 翻訳後修飾 / GNAS1遺伝子 / 遺伝子診断 / 同所性移植 / 生体内石灰化 / dentin matrix protein 1 / 超微構造 / Fibrous dysplasia / 骨芽細胞 / 骨基質蛋白質 / 骨基質 / DMP1 / 歯根 / ライブイメージング / 器官培養 / ヘルトビッヒ上皮鞘 / ＧＦＰ / GFP / Dmp1 / 石灰化 / 細胞内輸送 / 分泌経路 / 機能亢進型GNAS変異 / floxマウス / GNAS遺伝子変異 / 細胞内シグナル伝達異常 / 細胞内cAMP / 一次シリア / 軟骨 / 代謝 / ヒアルロン酸 / OA / 変形性顎関節症 / 機能亢進型GNAS変異疾患 / シグナル伝達異常 / 骨髄間質幹細胞 / 細胞内ｃAMP / 骨格形成 / 幹細胞 / シングルセル解析 Less

機能亢進型GNAS変異マウスを用いた線維性骨異形成症の病態解明と創薬展開
- Principal Investigator
  
  豊澤悟
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Osaka University
軟骨膜に含まれる骨軟骨前駆細胞の同定と、軟骨再生および骨損傷修復への応用Principal Investigator
- Principal Investigator
  
  宇佐美悠
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Osaka University
時空間的トランスクリプトミクスによる骨格系幹細胞の運命決定機構の解明
- Principal Investigator
  
  波多賢二
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
代謝リプログラミングを標的にした顎関節軟骨破壊性疾患に対する革新的アプローチ
- Principal Investigator
  
  犬伏俊博
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57070:Developmental dentistry-related
- Research Institution
  Osaka University
Research for abnormal cellular signaling in fibrous dysplasia and its drug discovery
- Principal Investigator
  
  Toyosawa Satoru
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 57:Oral science and related fields
- Research Institution
  Osaka University
Molecular and pathological understanding of oral early cancer using mouse chemical carcinogenesis modelPrincipal Investigator
- Principal Investigator
  
  Usami Yu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Significance of secretory processing of Dmp1 in the osteocyte function
- Principal Investigator
  
  Toyosawa Satoru
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Golgi-localized Fam20C phosphorylation and osteocyte functions
- Principal Investigator
  
  Toyosawa Satoru
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
In vivo live-imaging of the growing root tip to understand the molecular and cellular mechanism of the root development
- Principal Investigator
  
  Yamashiro Takashi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthodontics/Pediatric dentistry
- Research Institution
  Osaka University
Ultramicrostructural analysis of biomineralization processes of DMP1
- Principal Investigator
  
  TOYOSAWA Satoru
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Research for fibrous dysplasia using mutated GNAS1 transgenic mouse model
- Principal Investigator
  
  SATO Sunao
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Role of tumor microenvironment in formation of late-onset lymphnode metastasisPrincipal Investigator
- Principal Investigator
  
  USAMI Yu
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University
Trial research of fibrous dysplasia model transplanted with GNAS1 mutant cells
- Principal Investigator
  
  TOYOSAWA Satoru
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka University
Cross-interaction induced by direct adhesion between carcinoma cell and stromal cell in oral cancerPrincipal Investigator
- Principal Investigator
  
  USAMI Yu
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Morphological basic dentistry
- Research Institution
  Osaka University

All 2020 2019 2018 2017 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Overexpression of Fam20C in osteoblast in vivo leads to increased cortical bone formation and osteoclastic bone resorption2020
- Author(s)
  Hirose Katsutoshi、Ishimoto Takuya、Usami Yu、Sato Sunao、Oya Kaori、Nakano Takayoshi、Komori Toshihisa、Toyosawa Satoru
- Journal Title
  
  Bone
  
  Volume: - Pages: 115414-115414
- DOI
  10.1016/j.bone.2020.115414
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04368, KAKENHI-PROJECT-19K18944
[Journal Article] Possible Contribution of Wnt‐Responsive Chondroprogenitors to the Postnatal Murine Growth Plate2019
- Author(s)
  Usami Yu、Gunawardena Aruni T、Francois Noelle B、Otsuru Satoru、Takano Hajime、Hirose Katsutoshi、Matsuoka Masatake、Suzuki Akiko、Huang Jiahui、Qin Ling、Iwamoto Masahiro、Yang Wentian、Toyosawa Satoru、Enomoto‐Iwamoto Motomi
- Journal Title
  
  Journal of Bone and Mineral Research
  
  Volume: 34 Pages: 964-974
- DOI
  10.1002/jbmr.3658
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04368
[Journal Article] 顎骨の線維ー骨性病変 -歯原性腫瘍との鑑別点を含めて-2013
- Author(s)
  豊澤悟、村上秀明、宇佐美悠
- Journal Title
  
  病理と臨床
  
  Volume: 31 Pages: 527-534
- Data Source
  KAKENHI-PROJECT-23659877
[Journal Article] Intercellular adhesion molecule-1 (ICAM-1) expression correlates with oral cancer progression and induces macrophage/cancer cell adhesion.2013
- Author(s)
  Usami Y, Ishida K, Sato S, Kishino M, Kiryu M, Ogawa Y, Okura M, Fukuda Y, Toyosawa S
- Journal Title
  
  International Journal of Cancer
  
  Volume: 133(3) Pages: 5668-578
- DOI
  10.1002/ijc.28066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24593027, KAKENHI-PROJECT-24791960
[Journal Article] Neural hyperplasia in maxillary bone of the multiple endocrine neoplasia type 2B patient2011
- Author(s)
  Usami Y, Takenobu T, Kurihara R, Imai Y, Shinohara S, Fukuda Y, Toyosawa S
- Journal Title
  
  Oral Surg Oral Med Oral Pathol Oral Radiol Endod
  
  Volume: 112 Pages: 783-790
- DOI
  10.1016/j.tripleo.2011.07.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791765
[Presentation] 4NQO発癌モデルを用いた舌癌発生過程における血管の解析2020
- Author(s)
  宇佐美　悠、白銀　陽一朗、廣瀬　勝俊、佐藤　淳、豊澤　悟
- Organizer
  第62回歯科基礎医学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K11609
[Presentation] 4NQO発癌モデルを用いた舌癌発生過程における血管の解析2019
- Author(s)
  白銀　陽一朗、宇佐美　悠、廣瀬　勝俊、佐藤　淳、池邉　一典、豊澤　悟
- Organizer
  大阪大学歯学会第128回例会
- Data Source
  KAKENHI-PROJECT-17K11609
[Presentation] 4NQO発癌モデルを用いた舌癌発生過程における血管の解析2019
- Author(s)
  白銀　陽一朗、宇佐美　悠、廣瀬　勝俊、佐藤　淳、豊澤　悟
- Organizer
  第30回日本臨床口腔病理学会
- Data Source
  KAKENHI-PROJECT-17K11609
[Presentation] The role of Fam20C in dentin formation2019
- Author(s)
  Hirose K, Naniwa K, Usami Y, Oya K, Komori T, Toyosawa S
- Organizer
  American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04368
[Presentation] 象牙質形成におけるFam20Cの役割2019
- Author(s)
  廣瀬勝俊, 浪花耕平, 宇佐美悠, 佐藤淳, 大家香織, 小守壽文, 豊澤悟
- Organizer
  日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04368
[Presentation] 4NQO発癌モデルを用いた舌癌発生過程における血管の解析2019
- Author(s)
  白銀　陽一朗、宇佐美　悠、廣瀬　勝俊、佐藤　淳、池邉　一典、豊澤　悟
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-17K11609
[Presentation] 4NQO発癌モデルを用いた舌癌発生過程における血管の解析2019
- Author(s)
  宇佐美　悠、白銀　陽一朗、廣瀬　勝俊、佐藤　淳、豊澤　悟
- Organizer
  第61回歯科基礎医学会
- Data Source
  KAKENHI-PROJECT-17K11609
[Presentation] 4NQO発癌モデルを用いた舌癌発生過程における血管の解析2019
- Author(s)
  白銀　陽一朗、宇佐美　悠、廣瀬　勝俊、佐藤　淳、豊澤　悟
- Organizer
  第38回日本口腔腫瘍学会
- Data Source
  KAKENHI-PROJECT-17K11609
[Presentation] The role of Fam20C in Bone and tooth formation.2018
- Author(s)
  Hirose K, Usami Y, Sato S, Sharyo M, Oya K, Komori T, Toyosawa S
- Organizer
  American Society for Bone and Mineral Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04368
[Presentation] 3次元細胞培養モデルを用いた骨芽細胞から骨細胞への初期分化の検討2018
- Author(s)
  社領　美紀，佐藤　淳，宇佐美　悠，廣瀬　勝俊，白銀　陽一郎，豊澤　悟
- Organizer
  歯科基礎医学会学術大会
- Data Source
  KAKENHI-PROJECT-17H04368
[Presentation] 骨形成におけるゴルジ体キナーゼFam20Cの役割2018
- Author(s)
  廣瀬　勝俊、宇佐美　悠、佐藤　淳、大家　香織、社領　美紀、小守　壽文、豊澤　悟
- Organizer
  日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-17H04368
[Presentation] Analysis of the role of Fam20C in Fam20C-transgenic mice2017
- Author(s)
  Hirose K, Usami Y, Sato S, Sharyo M, Oya K, Komori T, Toyosawa S
- Organizer
  American Society for Bone and Mineral Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04368
[Presentation] 口腔扁平上皮癌細胞はマクロファージとの接着を介して膜型MMP 発現を亢進する2013
- Author(s)
  宇佐美　悠、松本　由香、佐藤　淳、岸野　万伸、小川　祐三、豊澤　悟
- Organizer
  第10回　日本病理学会カンファレンス
- Place of Presentation
  六甲山ホテル・兵庫
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] 口腔扁平上皮癌はマクロファージとの接着を介して膜型MMP発現を亢進する2013
- Author(s)
  宇佐美悠
- Organizer
  第24回日本臨床口腔病理学会総会・学術大会
- Place of Presentation
  日本大学・東京
- Year and Date
  2013-08-29
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] 口腔扁平上皮癌はマクロファージとの接着を介して膜型MMP発現を亢進する2013
- Author(s)
  宇佐美悠
- Organizer
  第10回日本病理学会カンファレンス
- Place of Presentation
  六甲山ホテル・兵庫
- Year and Date
  2013-08-02
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] 口腔扁平上皮癌の進展におけるマクロファージの働き2013
- Author(s)
  宇佐美　悠、松本　由香、佐藤　淳、岸野　万伸、小川　祐三、豊澤　悟
- Organizer
  第102回　日本病理学会総会
- Place of Presentation
  ロイトン札幌・北海道
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] A case of spontaneous malignant transformation of fibrous dysplasia on the right mandible2013
- Author(s)
  豊澤悟、佐藤淳、岸野万伸、宇佐美悠、野田百合、松本由香、小川祐三
- Organizer
  第24回日本臨床口腔病理学会総会・学術大会
- Place of Presentation
  日本大学理工学部1号館6階CSTホール
- Data Source
  KAKENHI-PROJECT-24592763
[Presentation] 口腔扁平上皮癌細胞はマクロファージとの接着を介して膜型MMP発現を亢進する2013
- Author(s)
  宇佐美　悠、松本　由香、佐藤　淳、岸野　万伸、小川　祐三、豊澤　悟、福田　康夫
- Organizer
  第24回　日本臨床口腔病理学会　総会・学術大会
- Place of Presentation
  日本大学・東京
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] 口腔扁平上皮癌の進展におけるマクロファージの働き2013
- Author(s)
  宇佐美悠
- Organizer
  第102回日本病理学会総会
- Place of Presentation
  ロイトン札幌・北海道
- Year and Date
  2013-06-08
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] 口腔扁平上皮癌の進展におけるマクロファージの働き2013
- Author(s)
  宇佐美　悠、松本　由香、佐藤　淳、岸野　万伸、小川　裕三、豊澤　悟
- Organizer
  第102回　日本病理学会総会
- Place of Presentation
  ロイトン札幌、北海道
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] 口腔扁平上皮癌におけるICAM-1発現は腫瘍進展とマクロファージ/癌細胞間の結合に関与する2012
- Author(s)
  宇佐美　悠、石田　健、佐藤　淳、岸野　万伸、小川　裕三、福田　康夫、豊澤　悟
- Organizer
  第23回　日本臨床口腔病理学会　総会・学術大会
- Place of Presentation
  東京医科歯科大学、東京
- Data Source
  KAKENHI-PROJECT-24791960
[Presentation] 下顎骨腫瘤の一例2012
- Author(s)
  佐藤淳、岸野万伸、宇佐美悠、小川裕三、豊澤悟
- Organizer
  第23回日本臨床口腔病理学会総会
- Place of Presentation
  東京医科歯科大学 M&D タワー
- Data Source
  KAKENHI-PROJECT-23659877
[Presentation] 下顎骨腫瘤の一例2012
- Author(s)
  佐藤淳、岸野万伸、宇佐美悠、小川裕三、豊澤悟
- Organizer
  第２３回日本臨床口腔病理学会総会・学術大会
- Place of Presentation
  東京医科歯科大学
- Data Source
  KAKENHI-PROJECT-24592763
[Presentation] 口腔扁平上皮癌におけるICAM-1発現は浸潤能、転移能とマクロファージの浸潤に関与する2011
- Author(s)
  宇佐美悠、石田健、大家香織、岸野万伸、佐藤淳、小川裕三、豊澤悟
- Organizer
  日本歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜県・長良川国際会議場
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-22791765
[Presentation] 口腔扁平上皮癌におけるintercellular adhesion molecule 1発現は転移能と腫瘍関連炎症細胞浸潤に関与する2011
- Author(s)
  宇佐美悠、福田康夫、石田健、岸野万信、佐藤淳、小川裕三、豊澤悟
- Organizer
  日本病理学会総会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-22791765
[Presentation] 口腔扁平上皮癌におけるICAM-1発現は浸潤能、転移能とマクロファーブの浸潤に関与する2011
- Author(s)
  宇佐美悠
- Organizer
  第53回日本歯科基礎医学会学術大会・総会
- Place of Presentation
  岐阜県・長良川国際会議場
- Year and Date
  2011-10-02
- Data Source
  KAKENHI-PROJECT-22791765
[Presentation] 口腔扁平上皮癌におけるintercellular adhesion molecule 1発現は転移能と腫瘍関連炎症細胞浸潤に関与する2011
- Author(s)
  宇佐美悠
- Organizer
  第100回日本病理学会総会
- Place of Presentation
  神奈川県・パシフィコ横浜
- Year and Date
  2011-04-30
- Data Source
  KAKENHI-PROJECT-22791765
[Presentation] 口腔扁平上皮癌におけるintercellular adhesion molecule 1発現は転移能と腫瘍関連炎症細胞浸潤に関与する2010
- Author(s)
  宇佐美悠
- Organizer
  日本癌学会学術総会
- Place of Presentation
  大阪府・大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22791765
[Presentation] 口腔扁平上皮癌におけるICAM1発現は転移能と腫瘍関連炎症細胞浸潤に関与する2010
- Author(s)
  宇佐美悠
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪・大阪国際会議場
- Year and Date
  2010-09-22
- Data Source
  KAKENHI-PROJECT-22791765
[Presentation] Establishment of therapeutic effect assessment animal model of fibrous dtsplasia
- Author(s)
  Sato S, Noda Y, Oya O, Usami Y, Kishino M, Ogawa Y, Toyosawa S
- Organizer
  17th International Congress on Oral Pathology and Medicine
- Place of Presentation
  Istanbul, Turkey
- Year and Date
  2014-05-25 – 2014-05-30
- Data Source
  KAKENHI-PROJECT-24592763

1. TOYOSAWA Satoru (30243249)

# of Collaborated Projects: 7 results

# of Collaborated Products: 16 results
2. ABE Makoto (40448105)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. SATO Jun (70335660)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
4. SAEKI Makio (30273692)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. YASUDA Hidehiro (60210259)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. Yamashiro Takashi (70294428)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 鵜澤成一 (30345285)

# of Collaborated Projects: 2 results

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8. 犬伏俊博 (30550941)

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9. 廣瀬勝俊 (00824898)

# of Collaborated Projects: 2 results

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10. 波多賢二 (80444496)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. MIURA Ichirou (70437383)

# of Collaborated Projects: 1 results

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12. ISHIMOTO Takuya (50508835)

# of Collaborated Projects: 1 results

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13. KAGAWA Ryousuke (40448147)

# of Collaborated Projects: 1 results

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14. KISHINO Mitsunobu (60346161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. MIHARA Kiyomi (00551920)

# of Collaborated Projects: 1 results

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16. ITOH Shinsuke (40633706)

# of Collaborated Projects: 1 results

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17. 石原嘉人 (70549881)

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18. 大家香織 (00779126)

# of Collaborated Projects: 1 results

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19. 古郷幹彦 (20205371)

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20. 黒坂寛 (20509369)

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21. 佐々木淳一 (50530490)

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22. 田熊一敞 (90289025)

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23. 松井崇浩 (50747037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 堀由美子 (60528785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 大倉正也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Usami Yu 宇佐美 悠

USAMI Yu 宇佐美 悠

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軟骨膜に含まれる骨軟骨前駆細胞の同定と、軟骨再生および骨損傷修復への応用Principal Investigator

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Molecular and pathological understanding of oral early cancer using mouse chemical carcinogenesis modelPrincipal Investigator

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Role of tumor microenvironment in formation of late-onset lymphnode metastasisPrincipal Investigator

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Cross-interaction induced by direct adhesion between carcinoma cell and stromal cell in oral cancerPrincipal Investigator

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[Journal Article] Overexpression of Fam20C in osteoblast in vivo leads to increased cortical bone formation and osteoclastic bone resorption2020

Usami Yu 宇佐美悠

USAMI Yu 宇佐美悠