Saji Shigehira 佐治重衡

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SAJI Shigehira 佐治重衡

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Researcher Number	80446567
Other IDs
Affiliation (Current)	2025: 福島県立医科大学, 医学部, 教授 2025: 京都大学, 医学研究科, 特定准教授
Affiliation (based on the past Project Information) *help	2025: 福島県立医科大学, 医学部, 教授 2019 – 2023: 福島県立医科大学, 医学部, 教授 2017: 福島県立医科大学, 医学部, 主任教授 2015 – 2017: 福島県立医科大学, 医学部, 教授 2015: 京都大学, 大学院医学研究科, 特定准教授 2011 – 2014: 京都大学, 医学(系)研究科(研究院), 准教授 2012: 京都大学, 医学研究科, 准教授
Review Section/Research Field	Principal Investigator Basic Section 55010:General surgery and pediatric surgery-related / General surgery Except Principal Investigator General surgery
Keywords	Principal Investigator ホルモン療法 / 乳癌 / NEDD4 / HER3 / エストロゲン受容体 / Breast cancer / Estrogen receptor / ホルモン受容体 / タンパク質分解 / breast cancer … More / ER / E3 リガーゼ / ユビキチン / ホルモン / 蛋白分解 / エストロゲン / タモキシフェン / 乳がん … More Except Principal Investigator 血管内皮増殖因子 / マイクロRNA / bevacizumab / 血管新生 / microRNA / 乳がん / 細胞運動 / NRP1 / VEGF / 乳癌 Less

免疫チェックポイント阻害薬が乳癌患者の女性ホルモン環境や妊孕性に与える影響Principal Investigator
- Principal Investigator
  
  佐治重衡
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukushima Medical University
乳癌におけるER分解制御因子NEDD4-1の生物学的機能と治療効果との相関性Principal Investigator
- Principal Investigator
  
  佐治重衡
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukushima Medical University
Regulatory factors for HER3 degradation in hormone receptor-positive breast cancer and its correlation with therapeutic efficacyPrincipal Investigator
- Principal Investigator
  
  Saji Shigehira
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Fukushima Medical University
Role of the alternation of steroid hormone level in the response and resistance to endocrine therapy for breast cancerPrincipal Investigator
- Principal Investigator
  
  Saji Shigehira
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Fukushima Medical University
Molecular mechanism in direct effect of VEGF onto breast cancer cells
- Principal Investigator
  
  SATO FUMIAKI
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General surgery
- Research Institution
  Kyoto University
Endocrine therapy for Estrogen receptorβ-positive Triple-negative breast cancerPrincipal Investigator
- Principal Investigator
  
  SAJI Shigehira
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General surgery
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation

[Journal Article] E3 Ubiquitin Ligase NEDD4 Affects Estrogen Receptor α Expression and the Prognosis of Patients with Hormone Receptor-Positive Breast Cancer2023
- Author(s)
  Natori Yutaka、Suga Junko、Tokuda Emi、Tachibana Kazunoshin、Imai Jun-ichi、Honma Reiko、Azami Yusuke、Noda Masaru、Sasaki Eisaku、Watanabe Shinya、Ohtake Tohru、Saji Shigehira
- Journal Title
  
  Cancers
  
  Volume: 15 Issue: 2 Pages: 539-539
- DOI
  10.3390/cancers15020539
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08697
[Journal Article] Fulvestrant plus palbociclib in advanced or metastatic hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer after fulvestrant monotherapy: Japan Breast Cancer Research Group-M07 (FUTURE trial)2023
- Author(s)
  Watanabe Kenichi、Niikura Naoki、Kikawa Yuichiro、Oba Mari、Kobayashi Kokoro、Tada Hiroshi、Ozaki Shinji、Toh Uhi、Yamamoto Yutaka、Tsuneizumi Michiko、Okuno Toshitaka、Iwakuma Nobutaka、Takeshita Takashi、Iwamoto Takayuki、Ishiguro Hiroshi、Masuda Norikazu、Saji Shigehira
- Journal Title
  
  Breast Cancer Research and Treatment
  
  Volume: 199 Issue: 2 Pages: 253-263
- DOI
  10.1007/s10549-023-06911-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08697
[Journal Article] Relationships between pathological factors and long-term outcomes in patients enrolled in two prospective randomized controlled trials comparing the efficacy of oral tegafur-uracil with CMF (N-SAS-BC01 trial and CUBC trial)2021
- Author(s)
  Ohno S, Saji S, Masuda N, Tsuda H, Akiyama F, Kurosumi M, Shimomura A, Sato N, Takao S, Ohsumi S, Tokuda Y, Inaji H, Watanabe T, Ohashi Y.
- Journal Title
  
  Breast Cancer Res Treat
  
  Volume: 186 Issue: 1 Pages: 135-147
- DOI
  10.1007/s10549-020-06018-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09079
[Journal Article] Risk of immunotherapy-related narcolepsy in genetically predisposed patients: a case report of narcolepsy after administration of pembrolizumab2020
- Author(s)
  Natori Yutaka、Sasaki Eisaku、Soeda Shu、Furukawa Shigenori、Azami Yusuke、Tokuda Emi、Kanbayashi Takashi、Saji Shigehira
- Journal Title
  
  Journal for ImmunoTherapy of Cancer
  
  Volume: 8 Issue: 2 Pages: e001164-e001164
- DOI
  10.1136/jitc-2020-001164
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08037, KAKENHI-PROJECT-19K09079
[Journal Article] Differential Involvement of Autophagy and Apoptosis in Response to Chemoendocrine and Endocrine Therapy in Breast Cancer: JBCRG-07TR.2019
- Author(s)
  Ueno T, Masuda N, Kamigaki S, Morimoto T, Saji S, Imoto S, Sasano H, Toi M.
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 20 Issue: 4 Pages: 984-984
- DOI
  10.3390/ijms20040984
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10067, KAKENHI-PROJECT-19K09079
[Journal Article] Changes in Recurrence Score by neoadjuvant endocrine therapy of breast cancer and their prognostic implication2019
- Author(s)
  Ueno Takayuki、Saji Shigehira、Masuda Norikazu、Iwata Hiroji、Kuroi Katsumasa、Sato Nobuaki、Takei Hiroyuki、Yamamoto Yutaka、Ohno Shinji、Yamashita Hiroko、Hisamatsu Kazufumi、Aogi Kenjiro、Sasano Hironobu、Toi Masakazu
- Journal Title
  
  ESMO Open
  
  Volume: 4 Issue: 1 Pages: e000476-e000476
- DOI
  10.1136/esmoopen-2018-000476
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08583, KAKENHI-PROJECT-15K10067, KAKENHI-PROJECT-19K09079
[Journal Article] Impact of clinical response to neoadjuvant endocrine therapy on patient outcome: a follow-up study of JFMC34-0601 multicentre prospective neoadjuvant endocrine trial.2018
- Author(s)
  Ueno T, Saji S, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Yamanaka T, Sasano H, Toi M.
- Journal Title
  
  ESMO Open.
  
  Volume: - Issue: 2 Pages: e000314-e000314
- DOI
  10.1136/esmoopen-2017-000314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10067, KAKENHI-PROJECT-15K10059, KAKENHI-PROJECT-18K08583
[Journal Article] Molecular diagnostics for precision medicine in breast cancer treatment: what does the future hold?2016
- Author(s)
  Saji S, Kimura-Tsuchiya R, Sasaki E.
- Journal Title
  
  Breast Cancer
  
  Volume: 23 Pages: 1-3
- Data Source
  KAKENHI-PROJECT-15K10059
[Journal Article] Clinical significance of the expression of autophagy-associated marker, beclin 1, in breast cancer patients who received neoadjuvant endocrine therapy.2016
- Author(s)
  Ueno T, Saji S, Sugimoto M, Masuda N, Kuroi K, Sato N, Takei H, Yamamoto Y, Ohno S, Yamashita H, Hisamatsu K, Aogi K, Iwata H, Imoto S, Sasano H, Toi M
- Journal Title
  
  BMC Cancer
  
  Volume: 16 Issue: 1 Pages: 230-230
- DOI
  10.1186/s12885-016-2270-9
- NAID
  120005973398
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10067, KAKENHI-PROJECT-26462860, KAKENHI-PROJECT-15K10059
[Journal Article] Combination of molecular-targeted drugs with endocrine therapy for hormone-resistant breast cancer2015
- Author(s)
  Saji S, Kimura-Tsuchiya R.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 20 Issue: 2 Pages: 268-272
- DOI
  10.1007/s10147-015-0799-2
- Data Source
  KAKENHI-PROJECT-15K10059
[Journal Article] 分子標的治療のための体細胞遺伝子検査の現況　ー乳癌ー2015
- Author(s)
  佐藤史顕、佐治重衡、戸井雅和
- Journal Title
  
  遺伝子MOOK
  
  Volume: 28 Pages: 81-86
- Data Source
  KAKENHI-PROJECT-24390301
[Journal Article] Genetic tumor evolution2014
- Author(s)
  佐藤史顕、佐治重衡、戸井雅和
- Journal Title
  
  Cancer Board 乳癌
  
  Volume: 7 Pages: 23-30
- Data Source
  KAKENHI-PROJECT-24390301
[Journal Article] 乳がんにおけるコンパニオン診断2014
- Author(s)
  佐藤史顕、佐治重衡、三上芳喜
- Journal Title
  
  医学のあゆみ
  
  Volume: 248(11) Pages: 845-850
- Data Source
  KAKENHI-PROJECT-24390301
[Journal Article] Potential clinical applications of matrix metalloproteinase inhibitors and their future prospects.2013
- Author(s)
  Li W, Saji S, Sato F, Noda M, Toi M
- Journal Title
  
  Int J Biol Markers.
  
  Volume: 28(2) Issue: 2 Pages: 117-30
- DOI
  10.5301/jbm.5000026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659610, KAKENHI-PROJECT-24390301
[Journal Article] 乳がんの治療　薬物療法　ホルモン療法の治療戦略2013
- Author(s)
  光藤悠子、佐治重衡
- Journal Title
  
  からだの科学-乳癌のすべて
  
  Volume: 277 Pages: 67-71
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] 乳がんの治療薬物療法ホルモン療法の治療戦略2013
- Author(s)
  光藤悠子、佐治重衡
- Journal Title
  
  からだの科学-乳癌のすべて
  
  Volume: 277巻 Pages: 67-71
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Ki-67 evaluation at the hottest spot predicts clinical outcome of patients with hormone receptor-positive/HER2-negative breast cancer treated with adjuvant tamoxifen monotherapy2013
- Author(s)
  Honma N, Horii R, Iwase T, Saji S, Younes M, Ito Y, Akiyama F.
- Journal Title
  
  Breast Cancer
  
  Volume: Mar 12. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Relationship between body mass index and preoperative treatment response to aromatase inhibitor exemestane in postmenopausal patients with primary breast cancer2012
- Author(s)
  Takada M, Saji S, Masuda N, Kuroi K,Sato N, Takei H, Yamamoto Y, Ohno S,Yamashita H, Hisamatsu K, Aogi K, Iwata H, Ueno T, Sasano H, Toi M
- Journal Title
  
  The Breast
  
  Volume: 21 Pages: 40-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Clinical importance of androgen receptor in breast cancer patients treated with adjuvant tamoxifen monotherapy2012
- Author(s)
  Honma N, Horii R, Iwase T, Saji S, Younes M, Ito Y, Akiyama F.
- Journal Title
  
  Breast Cancer
  
  Volume: Feb 4. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Association of Double-Positive FOXA1 and FOXP1 Immunoreactivities with Favorable Prognosis of Tamoxifen-Treated Breast Cancer Patients2012
- Author(s)
  Ijichi N, Shigekawa T, Ikeda K, Horie-Inoue K, Shimizu C, Saji S, Aogi K, Tsuda H, Osaki A, Saeki T, Inoue S.
- Journal Title
  
  Horm Cancer
  
  Volume: Apr 3. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] 性ホルモン代謝経路阻害剤：アロマターゼ阻害薬について2012
- Author(s)
  佐治重衡
- Journal Title
  
  日本臨床－分子標的治療薬
  
  Volume: 増刊号70(8) Pages: 103-108
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Association of Double-Positive FOXA1 and FOXP1 Immunoreactivities with Favorable Prognosis of Tamoxifen-Treated Breast Cancer Patients2012
- Author(s)
  Ijichi N, Shigekawa T, Ikeda K, Horie-Inoue K, Shimizu C, Saji S, Aogi K, Tsuda H, Osaki A, Saeki T, Inoue S.
- Journal Title
  
  Hormonal Cancer
  
  Volume: Apr. 3 [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Clinical importance of androgen receptor in breast cancer patients treated with adjuvant tamoxifen monotherapy.2012
- Author(s)
  Honma N, Horii R, Iwase T, Saji S, Younes M, Ito Y, Akiyama F.
- Journal Title
  
  Breast Cancer
  
  Volume: Feb 4. [Epub ahead of print]
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Fuel, electricity, ER and HER2-a hybrid-car model of breast cancer2012
- Author(s)
  Shigehira Saji, Fumiaki Sato, Naoto Ueno.
- Journal Title
  
  Nat Rev Clin Oncol
  
  Volume: 9(7) Issue: 7 Pages: 426-426
- DOI
  10.1038/nrclinonc.2012.9-c1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659610, KAKENHI-PROJECT-23659624
[Journal Article] Impact of body mass index on breast cancer in accordance with the life-stage of women2012
- Author(s)
  Suzuki R, Saji S, Toi M
- Journal Title
  
  Front. Oncol.
  
  Volume: 2 Pages: 123-123
- DOI
  10.3389/fonc.2012.00123
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624, KAKENHI-PROJECT-24501367
[Journal Article] Fuel and electricity, ER and HER2: a hybrid-car model of breast cancer(Correspondence).2012
- Author(s)
  Saji S, Sato F, Ueno NT
- Journal Title
  
  Nat Rev Clin Oncol
  
  Volume: 9(7) Pages: 426-426
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Immunohistochemical detection of breast cancer stem cells in hormone receptor-positive breast cancer and their role in response to endocrine therapy and clinical outcome2012
- Author(s)
  Hashimoto K, Shimizu C, Tsuda H, Saji S, Osaki A, Shigekawa T, Aogi K.
- Journal Title
  
  Oncology
  
  Volume: 82(3) Pages: 168-174
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Clinical importance of androgen receptor in breast cancer patients treated with adjuvant tamoxifen monotherapy.2012
- Author(s)
  Honma N, Horii R, Iwase T, Saji S, Younes M, Ito Y, Akiyama F
- Journal Title
  
  Breast Cancer
  
  Volume: 22 Issue: 1 Pages: 71-78
- DOI
  10.1007/s12282-013-0455-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Sex Steroid Hormones in Pairs of Tumor and Serum from Breast Cancer Patients and Pathobiological Role of Androstene-3β, 17β-diol.2011
- Author(s)
  Honma N, Saji S, Hirose M, Horiguchi S-I, Kuroi K, Hayashi S-I, Utsumi T, Harada N
- Journal Title
  
  Cancer Science
  
  Volume: 102(10) Pages: 1848-54
- NAID
  10030244004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Journal Article] Sex Steroid Hormones in Pairs of Tumor and Serum from Breast Cancer Patients and Pathobiological Role of Androstene-3 β 17 β -diol2011
- Author(s)
  Honma N, Saji S, Hirose M, Horiguchi S-I,Kuroi K, Hayashi S-I, Utsumi T, Harada N
- Journal Title
  
  Cancer Science
  
  Volume: 102(10) Pages: 1848-1854
- NAID
  10030244004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] Ubiquitin ligase NEDD4 promotes degradation of estrogen receptor in breast cancer and affects prognosis2022
- Author(s)
  名取穣, 須賀淳子, 徳田恵美, 立花和之進, 今井順一, 本間玲子, 阿左見祐介, 野田勝, 佐々木栄作, 渡邉慎哉, 大竹徹, 佐治重衡
- Organizer
  第19回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-22K08697
[Presentation] Ubiquitin ligase NEDD4 promotes degradation of estrogen receptor in breast cancer and affects prognosis2022
- Author(s)
  名取穣, 須賀淳子, 徳田恵美, 立花和之進, 今井順一, 本間玲子, 阿左見祐介, 野田勝, 佐々木栄作, 渡邉慎哉, 大竹徹, 佐治重衡
- Organizer
  第19回日本臨床腫瘍学会学術集会
- Data Source
  KAKENHI-PROJECT-19K09079
[Presentation] 乳癌診療におけるリキッドバイオプシーの将来展望2020
- Author(s)
  佐治重衡
- Organizer
  第４回 liquid biopsy 研究会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09079
[Presentation] 乳癌診療の新たな構築20202020
- Author(s)
  佐治重衡、徳田恵美、佐々木栄作
- Organizer
  第58回日本癌治療学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09079
[Presentation] ホルモン受容体陽性乳癌細胞におけるHER3分解機構の解明2018
- Author(s)
  須賀淳子、佐治重衡
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10059
[Presentation] From ER to ER, History and future of hormone dependent breast cancer research2017
- Author(s)
  Shigehira Saji
- Organizer
  International Cancer Research Symposium
- Place of Presentation
  Tokyo
- Year and Date
  2017-02-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K10059
[Presentation] ホルモン陽性乳がん細胞におけるエストロゲン刺激はHER3分解に関与する2017
- Author(s)
  須賀淳子、佐治重衡
- Organizer
  第２5回日本乳癌学会学術総会
- Data Source
  KAKENHI-PROJECT-15K10059
[Presentation] Overcoming endocrine therapy resistance in breast cancer, a cat and mouse game?2016
- Author(s)
  Shigehira Saji, Reiko Kimura, Eisaku Sasaki
- Organizer
  第14回日本臨床腫瘍学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2016-07-28
- Data Source
  KAKENHI-PROJECT-15K10059
[Presentation] Mechanism of endocrine therapy resistance: How to overcome ?2016
- Author(s)
  Shigehira Saji
- Organizer
  68th Congress of The Korean Surgical Society
- Place of Presentation
  Seoul
- Year and Date
  2016-11-03
- Invited
- Data Source
  KAKENHI-PROJECT-15K10059
[Presentation] 臓器がんの薬物療法　乳がん：ホルモン療法の基礎2015
- Author(s)
  佐治重衡
- Organizer
  第１３回日本臨床腫瘍学会学術集会
- Place of Presentation
  札幌市
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K10059
[Presentation] 乳がんにおけるゲノム網羅的解析・多遺伝子解析と内分泌療法個別化2015
- Author(s)
  佐治重衡
- Organizer
  第５３回日本癌治療学会学術集会
- Place of Presentation
  京都市
- Year and Date
  2015-10-29
- Invited
- Data Source
  KAKENHI-PROJECT-15K10059
[Presentation] 乳癌細胞における血管内皮増殖因子(VEGF)関連microRNAの解析2013
- Author(s)
  木曾末厘乃、佐藤史顕、蒲風玲、佐治重衡、戸井雅和
- Organizer
  日本分子標的治療学会
- Place of Presentation
  京都国際会館、京都
- Data Source
  KAKENHI-PROJECT-24390301
[Presentation] 内分泌療法の進歩と今後の役割2012
- Author(s)
  佐治重衡、佐藤史顕
- Organizer
  第10回日本臨床腫瘍学会学術集会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2012-07-27
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] Serum concentration of Estrone (E1), not Estradiol (E2), is the independent predictive factor of response to neo-adjuvant exemestane treatment in postmenopausal breast cancer patients:JFMC 34-0601 TR2012
- Author(s)
  Saji S, Takada M, Honma N, Masuda N, Yamamoto Y, Kuroi K, Yamashita H, Ohno S, Ueno T, Toi M.
- Organizer
  The 37th European Society of Medical Oncology 2012 Congress
- Place of Presentation
  Austria Center Vienna(オーストリア)
- Year and Date
  2012-10-01
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] 進行・再発乳がんをめぐる新しい治療戦略2012
- Author(s)
  佐治重衡、佐藤史顕
- Organizer
  第71回日本癌学会学術総会(シンポジウム)
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] 乳癌における estrogen receptor-beta の tamoxifen効果予測性についての検討2012
- Author(s)
  本間尚子、堀井理絵、岩瀬拓士、新井冨生、佐治重衡、伊藤良則、秋山太
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌(北海道)
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] Factors Affecting Aromatase Inhibitors Responsiveness2012
- Author(s)
  Saji S
- Organizer
  Korean Surgical International Symposium(KOSIS)2012
- Place of Presentation
  COEX(韓国)
- Year and Date
  2012-12-01
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] ホルモン療法が効かないとは？　耐性克服へのアプローチ2011
- Author(s)
  佐治重衡
- Organizer
  第４９回　日本癌治療学会学術集会(招待講演)
- Place of Presentation
  名古屋国際会議場（愛知県）
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] ホルモン療法が効かないとは?耐性克服へのアプローチ2011
- Author(s)
  佐治重衡
- Organizer
  第49回日本癌治療学会学術集会
- Place of Presentation
  名古屋国際会議場(愛知県)
- Year and Date
  2011-10-27
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] Explore the factors predicting response of endocrine therapy for breast cancer2011
- Author(s)
  Saji S, Sato F
- Organizer
  The Capital International Cancer Conference (CICC) 2011(招待講演)
- Place of Presentation
  China National Convention Center（中国）
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] Explore the factors predicting response of endocrine therapy for breast cancer2011
- Author(s)
  Saji S, Sato F
- Organizer
  The Capital International Cancer Conference (CICC) 2011
- Place of Presentation
  China National Convention Center(中国)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] "Biology based Medicine "　has come to breast cancer drug therapy2011
- Author(s)
  佐治重衡
- Organizer
  第９回日本臨床腫瘍学会学術集会(招待講演)
- Place of Presentation
  パシフイコ横浜（神奈川県）
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] 乳癌におけるestrogen receptor-betaのtamoxifen効果予測性についての検討
- Author(s)
  本間尚子、堀井理絵、岩瀬拓士、新井冨生、佐治重衡、伊藤良則、秋山太
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ﾛｲﾄﾝ札幌（北海道）
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] Factors Affecting Aromatase Inhibitors Responsiveness
- Author(s)
  Saji S.
- Organizer
  Korean Surgical International Symposium (KOSIS) 2012
- Place of Presentation
  COEX,(韓国）
- Invited
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] 内分泌療法の進歩と今後の役割
- Author(s)
  佐治重衡、佐藤史顕
- Organizer
  第10回日本臨床腫瘍学会学術集会(The 10th Annual Meeting of Japanese Society of Medical Oncology)
- Place of Presentation
  大阪国際会議場（大阪府）
- Invited
- Data Source
  KAKENHI-PROJECT-23659624
[Presentation] 進行・再発乳がんをめぐる新しい治療戦略
- Author(s)
  佐治重衡、佐藤史顕
- Organizer
  第71回日本癌学会学術総会　（シンポジウム）
- Place of Presentation
  ﾛｲﾄﾝ札幌(北海道）
- Invited
- Data Source
  KAKENHI-PROJECT-23659624

1. SATO FUMIAKI (20467426)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. HONMA Naoko (70321875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. TOI Masakazu (10207516)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. UENO Takayuki (40452362)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. MIKAMI Yoshiki (90248245)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. OHTAKE Toru (50363750)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SUGA Junko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. TANAKA Nobuyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 神林崇

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 武井寛幸

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Saji Shigehira 佐治 重衡

SAJI Shigehira 佐治 重衡

Research Projects

Research Products

Co-Researchers

免疫チェックポイント阻害薬が乳癌患者の女性ホルモン環境や妊孕性に与える影響Principal Investigator

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乳癌におけるER分解制御因子NEDD4-1の生物学的機能と治療効果との相関性Principal Investigator

Principal Investigator

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Regulatory factors for HER3 degradation in hormone receptor-positive breast cancer and its correlation with therapeutic efficacyPrincipal Investigator

Principal Investigator

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Review Section

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Role of the alternation of steroid hormone level in the response and resistance to endocrine therapy for breast cancerPrincipal Investigator

Principal Investigator

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Research Institution

Molecular mechanism in direct effect of VEGF onto breast cancer cells

Principal Investigator

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Endocrine therapy for Estrogen receptorβ-positive Triple-negative breast cancerPrincipal Investigator

Principal Investigator

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[Journal Article] E3 Ubiquitin Ligase NEDD4 Affects Estrogen Receptor α Expression and the Prognosis of Patients with Hormone Receptor-Positive Breast Cancer2023

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[Journal Article] Fulvestrant plus palbociclib in advanced or metastatic hormone receptor-positive/human epidermal growth factor receptor 2-negative breast cancer after fulvestrant monotherapy: Japan Breast Cancer Research Group-M07 (FUTURE trial)2023

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[Journal Article] Relationships between pathological factors and long-term outcomes in patients enrolled in two prospective randomized controlled trials comparing the efficacy of oral tegafur-uracil with CMF (N-SAS-BC01 trial and CUBC trial)2021

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[Journal Article] Risk of immunotherapy-related narcolepsy in genetically predisposed patients: a case report of narcolepsy after administration of pembrolizumab2020

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[Journal Article] Differential Involvement of Autophagy and Apoptosis in Response to Chemoendocrine and Endocrine Therapy in Breast Cancer: JBCRG-07TR.2019

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[Journal Article] Changes in Recurrence Score by neoadjuvant endocrine therapy of breast cancer and their prognostic implication2019

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[Journal Article] Impact of clinical response to neoadjuvant endocrine therapy on patient outcome: a follow-up study of JFMC34-0601 multicentre prospective neoadjuvant endocrine trial.2018

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[Journal Article] Molecular diagnostics for precision medicine in breast cancer treatment: what does the future hold?2016

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Saji Shigehira 佐治重衡

SAJI Shigehira 佐治重衡

[Journal Article] 分子標的治療のための体細胞遺伝子検査の現況　ー乳癌ー2015

[Journal Article] 乳がんの治療　薬物療法　ホルモン療法の治療戦略2013

[Journal Article] 乳がんの治療薬物療法ホルモン療法の治療戦略2013