Sakane Hiroshi 坂根洋

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SAKANE Hiroshi 坂根洋

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Researcher Number	80457291
Other IDs
Affiliation (Current)	2025: 福山大学, 薬学部, 准教授
Affiliation (based on the past Project Information) *help	2012 – 2013: 獨協医科大学, 医学部, 助教 2011: 大阪大学, 医学系・研究科, 招へい研究員 2011: 大阪大学, 医学系研究科, 招へい研究員 2010: 大阪大学, 医学系研究科, 特任研究員
Review Section/Research Field	Principal Investigator General medical chemistry / Pathological medical chemistry
Keywords	Principal Investigator Wnt / クラスリン / 選別輸送 / 上皮細胞 / リサイクリング / 細胞内シグナル伝達 / 脂質ラフト / エンドサイトーシス / LRP6 / Glypican4 / Dkk1 / 分子病態学

Selective secretion mechanism of Wnt in polarized epithelial cellsPrincipal Investigator
- Principal Investigator
  
  SAKANE Hiroshi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Dokkyo Medical University
Regulation of Wnt signaling pathway by Dkk1Principal Investigator
- Principal Investigator
  
  SAKANE Hiroshi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Osaka University

All 2014 2013 2012 2011 2010

All Journal Article Presentation

[Journal Article] α-Taxilin interacts with soring nexin 4 and participates in the recycling pathway of transferrin receptor.2014
- Author(s)
  Sakane, H., Horii, Y., Nogami, S., Kawano, Y., Kaneko-Kawano, T., and Shirataki, H.
- Journal Title
  
  PloS ONE
  
  Volume: 9 Issue: 4 Pages: e93509-e93509
- DOI
  10.1371/journal.pone.0093509
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23659403, KAKENHI-PUBLICLY-24113515, KAKENHI-PROJECT-24790280, KAKENHI-PUBLICLY-26113712, KAKENHI-PROJECT-26450055
[Journal Article] The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by distinct mechanisms.2013
- Author(s)
  Yamamoto, H., Awada, C., Hanaki, H., Sakane, H., Tsujimoto, I., Takahashi, Y., Takao, T., and Kikuchi, A.
- Journal Title
  
  J. Cell Sci.
  
  Volume: 126 Pages: 2931-2943
- DOI
  10.1242/jcs.126052
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-23112001, KAKENHI-PLANNED-23112004, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-24790280, KAKENHI-PROJECT-25250018
[Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling2012
- Author(s)
  Sakane H., Yamamoto H., Matsumoto S., Sato A., and Kikuchi A.
- Journal Title
  
  J. Cell Sci
  
  Volume: 125 Pages: 449-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790316
[Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling2012
- Author(s)
  Sakane, H., et.al.
- Journal Title
  
  J.Cell Sci.
  
  Volume: 125 Issue: 2 Pages: 449-460
- DOI
  10.1242/jcs.091876
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21249017, KAKENHI-PUBLICLY-22019025, KAKENHI-PROJECT-22770127, KAKENHI-PROJECT-22790316, KAKENHI-ORGANIZER-23112001, KAKENHI-PROJECT-23590333, KAKENHI-PROJECT-23650594, KAKENHI-PROJECT-23790333, KAKENHI-PROJECT-24590378, KAKENHI-PLANNED-23112004
[Journal Article] LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse2010
- Author(s)
  Sakane H., et al.
- Journal Title
  
  J.Cell Sci.
  
  Volume: 123 Pages: 360-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790316
[Journal Article] LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse2010
- Author(s)
  Sakane H., Yamamoto H., and Kikuchi A.
- Journal Title
  
  J. Cell Sci
  
  Volume: 123 Pages: 360-368
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790316
[Presentation] Glypican-4の脂質ラフトへの局在に依存したWntシグナル伝達の制御機構2011
- Author(s)
  坂根洋
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館(京都府)
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22790316
[Presentation] Glypican-4の脂質ラフトへの局在に依存したWntシグナル伝達の制御機構2011
- Author(s)
  坂根洋、山本英樹、松本真司、佐藤朗、菊池章
- Organizer
  第84回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2011-09-23
- Data Source
  KAKENHI-PROJECT-22790316
[Presentation] 脂質ラフトにおけるWnt3a依存性のLRP6リン酸化の制御機構の解析2010
- Author(s)
  坂根洋、山本英樹、菊池章
- Organizer
  第83回日本生化学会大会・第33回日本分子生物学会年会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790316
[Presentation] 脂質ラフトにおけるWnt3a依存性のLRP6リン酸化の制御機構の解析2010
- Author(s)
  坂根洋
- Organizer
  第33回日本分子生物学会年会第83回日本生化学会大会合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22790316

1. 白瀧博通

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 菊池章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Sakane Hiroshi 坂根 洋

SAKANE Hiroshi 坂根 洋

Research Projects

Research Products

Co-Researchers

Selective secretion mechanism of Wnt in polarized epithelial cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of Wnt signaling pathway by Dkk1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] α-Taxilin interacts with soring nexin 4 and participates in the recycling pathway of transferrin receptor.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by distinct mechanisms.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling2012

Author(s)

Journal Title

Data Source

[Journal Article] Localization of glypican-4 in different membrane microdomains is involved in the regulation of Wnt signaling2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse2010

Author(s)

Journal Title

Data Source

[Journal Article] LRP6 is internalized by Dkk1 to suppress its phosphorylation in the lipid raft and is recycled for reuse2010

Author(s)

Journal Title

Data Source

[Presentation] Glypican-4の脂質ラフトへの局在に依存したWntシグナル伝達の制御機構2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Glypican-4の脂質ラフトへの局在に依存したWntシグナル伝達の制御機構2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 脂質ラフトにおけるWnt3a依存性のLRP6リン酸化の制御機構の解析2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 脂質ラフトにおけるWnt3a依存性のLRP6リン酸化の制御機構の解析2010

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

Sakane Hiroshi 坂根洋

SAKANE Hiroshi 坂根洋