Takahashi Akari 高橋あかり

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TAKAHASHI Akari 高橋あかり

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Researcher Number	80457697
Affiliation (Current)	2025: 札幌医科大学, 医学部, 研究員
Affiliation (based on the past Project Information) *help	2017 – 2019: 札幌医科大学, 医学部, 研究員 2012 – 2014: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Digestive surgery / Thoracic surgery
Keywords	Principal Investigator がん幹細胞 / エピジェネティクス / 大腸がん / 腫瘍微小環境 / メチル化 / 脱分化 / 造腫瘍 / 腫瘍起始能 / SMCP / 肺がん

Analysis of defined factor of de-differentiation of colon cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Akari
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Digestive surgery
- Research Institution
  Sapporo Medical University
Molecular analysis of lung cancer stem cell related gene, SMCPPrincipal Investigator
- Principal Investigator
  
  TAKAHASHI Akari
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Thoracic surgery
- Research Institution
  Sapporo Medical University

All 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice.2015
- Author(s)
  Kasamatsu J, Takahashi S, Azuma M, Matsumoto M, Morii-Sakai A, Imamura M, Teshima T, Takahashi A, Hirohashi Y, Torigoe T, Sato N, Seya T.
- Journal Title
  
  Immunobiology
  
  Volume: 220 Issue: 1 Pages: 74-82
- DOI
  10.1016/j.imbio.2014.08.017
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
[Journal Article] Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.2014
- Author(s)
  Morita R, Nishizawa S, Torigoe T, Takahashi A, Tamura Y, Tsukahara T, Kanaseki T, Sokolovskaya A, Kochin V, Kondo T, Hashino S, Asaka M, Hara I, Hirohashi Y, Sato N.
- Journal Title
  
  Cancer Sci
  
  Volume: 105 Issue: 4 Pages: 389-395
- DOI
  10.1111/cas.12362
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-25462344
[Journal Article] DNA methyltransferase 1 is essential for initiation of the colon cancers2013
- Author(s)
  Morita R,Hirohashi Y,Suzuki H, et al
- Journal Title
  
  Experimental and Molecular Pathology
  
  Volume: 94 Issue: 2 Pages: 322-329
- DOI
  10.1016/j.yexmp.2012.10.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23501261, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PUBLICLY-25134715, KAKENHI-PROJECT-25430115
[Journal Article] Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.2013
- Author(s)
  Yasuda K, Torigoe T, Morita R, Kuroda T, Takahashi A, Matsuzaki J, Kochin V, Asanuma H, Hasegawa T, Saito T, Hirohashi Y, Sato N.
- Journal Title
  
  PLoS One
  
  Volume: 8(8) Issue: 8 Pages: e68187-e68187
- DOI
  10.1371/journal.pone.0068187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
[Journal Article] AIDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and AIDH1 high expression is associated with poor prognosis.2013
- Author(s)
  Kuroda T, Hirohashi Y, Torigoe T, Yasuda K, Takahashi A, Asanuma H, Morita R, Mariya T, Asano T, Mizuuchi M, Saito T, Sato N.
- Journal Title
  
  PLoS One
  
  Volume: 8(6) Issue: 6 Pages: e65158-e65158
- DOI
  10.1371/journal.pone.0065158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
[Journal Article] Preferential expression of cancer/testis genes in cancer stem-like cells : proposal of a novel sub-category, cancer/testis/stem gene.2013
- Author(s)
  Yamada R, Takahashi A, Torigoe T, Morita R, Tamura Y, Tsukahara T, Kanaseki T, Kubo T, Watarai K, Kondo T, Hirohashi Y, Sato N.
- Journal Title
  
  Tissue Antigens.
  
  Volume: 81(6) Issue: 6 Pages: 428-34
- DOI
  10.1111/tan.12113
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J02959, KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467
[Journal Article] Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor.2013
- Author(s)
  Nishida S, Hirohashi Y, Torigoe T, Inoue R, Kitamura H, Tanaka T, Takahashi A, Asanuma H, Masumori N, Tsukamoto T, Sato N.
- Journal Title
  
  Cancer Sci
  
  Volume: 104 Issue: 4 Pages: 431-6
- DOI
  10.1111/cas.12104
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24592399, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-221S0001
[Journal Article] Expression and function of FERMT genes in colon carcinoma cells2013
- Author(s)
  Kiriyama K, Hirohashi Y, Torigoe T, Kubo T, Tamura Y, Kanaseki T, Takahashi A, et al.
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 167-73
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24791467
[Journal Article] Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.2013
- Author(s)
  Michifuri Y, Hirohashi Y, Torigoe T, Miyazaki A, Fujino J, Tamura Y, Tsukahara T, Kanaseki T, Kobayashi J, Sasaki T, Takahashi A, Nakamori K, Yamaguchi A, Hiratsuka H, Sato N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 439 Issue: 1 Pages: 96-102
- DOI
  10.1016/j.bbrc.2013.08.021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659901, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-24792005, KAKENHI-PROJECT-25462344, KAKENHI-PROJECT-25463115
[Journal Article] Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells.2013
- Author(s)
  Takahashi A, Hirohashi Y, Torigoe T, Tamura Y, Tsukahara T, Kanaseki T, Kochin V, Saijo H, Kubo T, Nakatsugawa M, Asanuma H, Hasegawa T, Kondo T, Sato N.
- Journal Title
  
  PLoS One
  
  Volume: 8 Issue: 11 Pages: e69095-e69095
- DOI
  10.1371/journal.pone.0069095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590449, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24791467, KAKENHI-PROJECT-25462344
[Journal Article] Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes2012
- Author(s)
  Takahashi A, Torigoe T, Tamura Y, Kanaseki T, Tsukahara T, Sasaki Y, Kameshima H, Tsuruma T, Hirata K, Tokino T, Hirohashi Y, Sato N
- Journal Title
  
  Cell Stress Chaperones
  
  Volume: 17 Issue: 6 Pages: 757-763
- DOI
  10.1007/s12192-012-0348-0
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590427, KAKENHI-PROJECT-23590920, KAKENHI-PROJECT-23659658, KAKENHI-PROJECT-24590448, KAKENHI-PROJECT-24659165, KAKENHI-PROJECT-24659592, KAKENHI-PROJECT-24791467
[Presentation] Variant form of SMCP increases tumor initiation capacity of the stem cell population of lung adenocarcinoma cells2013
- Author(s)
  Takahashi A, Torigoe T, Hirohashi Y, Tamura Y, Tsukahara T, Kanaseki T, Saijo H, Asanuma H, Sato N
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-24791467
[Presentation] Identification of the naturally processed peptide derived from FAM83B that is specifically expressed in cancer initiating cells2013
- Author(s)
  Takahashi A, Kochin V, Kanaseki T, Hirohashi Y, Kawami S, Suzuki Y, Torigoe T, Sato N
- Organizer
  第42回日本免疫学会学術集会
- Place of Presentation
  幕張メッセ
- Data Source
  KAKENHI-PROJECT-24791467

1. HIROHASHI Yoshihiko

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
2. 田村保明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 佐藤昇志

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takahashi Akari 高橋 あかり

TAKAHASHI Akari 高橋 あかり

Research Projects

Research Products

Co-Researchers

Analysis of defined factor of de-differentiation of colon cancer stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular analysis of lung cancer stem cell related gene, SMCPPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] PolyI:C and mouse survivin artificially embedding human 2B peptide induce a CD4+ T cell response to autologous survivin in HLA-A*2402 transgenic mice.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heat shock protein DNAJB8 is a novel target for immunotherapy of colon cancer-initiating cells.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DNA methyltransferase 1 is essential for initiation of the colon cancers2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ovarian cancer stem cells are enriched in side population and aldehyde dehydrogenase bright overlapping population.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] AIDH1-high ovarian cancer stem-like cells can be isolated from serous and clear cell adenocarcinoma cells, and AIDH1 high expression is associated with poor prognosis.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preferential expression of cancer/testis genes in cancer stem-like cells : proposal of a novel sub-category, cancer/testis/stem gene.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression and function of FERMT genes in colon carcinoma cells2013

Author(s)

Journal Title

Data Source

[Journal Article] Small proline-rich protein-1B is overexpressed in human oral squamous cell cancer stem-like cells and is related to their growth through activation of MAP kinase signal.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ectopically expressed variant form of sperm mitochondria-associated cysteine-rich protein augments tumorigenicity of the stem cell population of lung adenocarcinoma cells.2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Heat shock enhances the expression of cytotoxic granule proteins and augments the activities of tumor-associated antigen-specific cytotoxic T lymphocytes2012

Author(s)

Journal Title

DOI

Data Source

[Presentation] Variant form of SMCP increases tumor initiation capacity of the stem cell population of lung adenocarcinoma cells2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Identification of the naturally processed peptide derived from FAM83B that is specifically expressed in cancer initiating cells2013

Author(s)

Organizer

Place of Presentation

Takahashi Akari 高橋あかり

TAKAHASHI Akari 高橋あかり