tanaka shinya 田中伸弥

… Alternative Names

TANAKA SHINYA 田中伸弥

田中伸弥タナカシンヤ

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Researcher Number	80462703
Other IDs
Affiliation (Current)	2025: 九州大学, 生体防御医学研究所, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 九州大学, 生体防御医学研究所, 准教授 2018: 九州大学, 生体防御医学研究所, 助教 2017: 東京理科大学, 研究推進機構生命医科学研究所, 助教 2016: 大阪大学, 免疫学フロンティア研究センター, 特任助教(常勤) 2015: 大阪大学, 免疫フロンティア研究センター, 特任助教 … More 2013 – 2015: 大阪大学, 免疫学フロンティア研究センター, 特任助教 2014: 大阪大学, 学内共同利用施設等, 助教 2009: 理研, 研究員 2008: The Institute of Physical and Chemical Research, シグナル・ネットワーク研究チーム, 基礎科学特別研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 54020:Connective tissue disease and allergy-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields / Transformative Research Areas, Section (II) / Complex systems / Experimental pathology / Collagenous pathology/Allergology / Immunology / 膠原病・アレルギー・感染症内科学
Keywords	Principal Investigator 免疫寛容 / 自己免疫疾患 / Self tolerance / DNA demethylation / B cells / 抗原特異的免疫反応制御 / 細胞間相互作用 / 制御性B細胞 / 抗原選択的抗体産生制御 / 自己反応性リンパ球 … More / 自己反応性シンギュラリティリンパ球 / Tet分子 / 末梢寛容 / 能動的DNA脱メチル化 / B細胞自己寛容 / B細胞ホメオスターシス / B細胞分化 / Ten-Eleven translocation / Ten-Eleven Translocation / DNA methylation / RANK / FDC / 濾胞T細胞 / IgE / Th2 / サイトカイン Less

Research Projects
(9 results)
Research Products
(24 results)

抗原選択的免疫応答制御を実現する為の基盤システムの構築Principal Investigator
- Principal Investigator
  
  田中伸弥
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Kyushu University
末梢自己反応性B細胞の生体恒常性維持における役割の解明Principal Investigator
- Principal Investigator
  
  田中伸弥
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyushu University
自己反応性シンギュラリティT細胞をラベリングする新規システムの構築と動態解析Principal Investigator
- Principal Investigator
  
  田中伸弥
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Kyushu University
制御性B細胞を用いた物質共生制御Principal Investigator
- Principal Investigator
  
  田中伸弥
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (II)
- Research Institution
  Kyushu University
The regulation of B cell tolerance by DNA demethylase, Ten-eleven translocationPrincipal Investigator
- Principal Investigator
  
  Tanaka Shinya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54020:Connective tissue disease and allergy-related
- Research Institution
  Kyushu University
The regulation of memory B cell by DNA demethylationPrincipal Investigator
- Principal Investigator
  
  TANAKA SHINYA
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University
  Tokyo University of Science
  Osaka University
Role of RANK expressed on FDCs in humoral immunityPrincipal Investigator
- Principal Investigator
  
  TANAKA SHINYA
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Osaka University
C/EBP alpha による液性免疫制御機構の解明Principal Investigator
- Principal Investigator
  
  田中伸弥
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Osaka University
ゲノム情報を基盤としたアレルギーメカニズム解明Principal Investigator
- Principal Investigator
  
  田中伸弥
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  膠原病・アレルギー・感染症内科学
- Research Institution
  The Institute of Physical and Chemical Research

All 2023 2022 2021 2020 2019 2018 2016 2015 2014 2008

All Journal Article Presentation Book

[Book] Advances in Experimental Medicine and Biology (Chapter 4 of B Cell Receptor Signaling)2020
- Author(s)
  Shinya Tanaka
- Publisher
  Springer International Publishing
- Data Source
  KAKENHI-PROJECT-19K08883
[Journal Article] Upregulated Fcrl5 disrupts B cell anergy and causes autoimmune disease2023
- Author(s)
  Chisato Ono, Shinya Tanaka, Keiko Myouzen, Takeshi Iwasaki, Mahoko Ueda, Yoshinao Oda, Kazuhiko Yamamoto, Yuta Kochi, Yoshihiro Baba
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 14 Pages: 01-14
- DOI
  10.3389/fimmu.2023.1276014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19547, KAKENHI-PROJECT-22KJ2376, KAKENHI-PROJECT-21H02753, KAKENHI-PROJECT-23K24371
[Journal Article] Quiescent B Cells Acquire Sensitivity to Cell Cycle Arresting Agents by B Cell Receptor Stimulation2022
- Author(s)
  Takanatsu Hosokawa, Shinya Tanaka, Takeshi Mori, Yoshihiro Baba, Yoshiki Katayama
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 45 Issue: 7 Pages: 847-850
- DOI
  10.1248/bpb.b22-00176
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2022-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19547, KAKENHI-PUBLICLY-21H05530, KAKENHI-PROJECT-21K19055, KAKENHI-PUBLICLY-21H00429, KAKENHI-PROJECT-23K24371
[Journal Article] Silencing and activating anergic B cells2021
- Author(s)
  Shinya Tanaka, Wataru Ise, Yoshihiro Baba, Tomohiro Kurosaki
- Journal Title
  
  Immunological reviews
  
  Volume: 307 Issue: 1 Pages: 43-52
- DOI
  10.1111/imr.13053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08883, KAKENHI-PROJECT-19H01028, KAKENHI-PROJECT-20H03503, KAKENHI-PROJECT-22K19547, KAKENHI-PUBLICLY-21H05530, KAKENHI-PUBLICLY-21H00429, KAKENHI-PROJECT-23K24371
[Journal Article] Tet2 and Tet3 in B cells are required to repress CD86 and prevent autoimmunity2020
- Author(s)
  Tanaka, S. Ise, W. Inoue, T. Ito, A. Ono, C. Shima, Y. Sakakibara, S. Nakayama, M. Fujii, K. Miura, I. Sharif, J. Koseki, H. Koni, P. A. Raman, I. Li, Q. Z. Kubo, M. Fujiki, K. Nakato, R. Shirahige, K. Araki, H. Miura, F. Ito, T. Kawakami, E. Baba, Y. Kurosaki, T.
- Journal Title
  
  Nature Immunology
  
  Volume: 21 Issue: 8 Pages: 950-961
- DOI
  10.1038/s41590-020-0700-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08883, KAKENHI-PROJECT-20K21384, KAKENHI-PLANNED-17H06331, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-18H02626, KAKENHI-PROJECT-19H03491, KAKENHI-PROJECT-19K22537, KAKENHI-PROJECT-20H03503
[Journal Article] Tet DNA demethylase is required for plasma cell differentiation by controlling expression levels of IRF42020
- Author(s)
  Fujii, K. Tanaka, S. Hasegawa, T. Narazaki, M. Kumanogoh, A. Koseki, H. Kurosaki, T. Ise, W.
- Journal Title
  
  International Immunology
  
  Volume: 32 Issue: 10 Pages: 683-690
- DOI
  10.1093/intimm/dxaa042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08883, KAKENHI-PLANNED-19H05745, KAKENHI-PROJECT-16H02622, KAKENHI-PROJECT-17K10002, KAKENHI-PROJECT-20H03503
[Journal Article] Trim33 mediates the proinflammatory function of Th17 cells.2018
- Author(s)
  Tanaka S, Jiang Y, Martinez GJ, Tanaka K, Yan X, Kurosaki T, Kaartinen V, Feng XH, Tian Q, Wang X, Dong C
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 215 Pages: 1853-1868
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08738
[Journal Article] Regulation of Pathogenic T Helper 17 Cell Differentiation by Steroid Receptor Coactivator-32018
- Author(s)
  Tanaka K, Martinez GJ, Yan X, Long W, Ichiyama K, Chi X, Kim BS, Reynolds JM, Chung Y, Tanaka S, Liao L, Nakanishi Y, Yoshimura A, Zheng P, Wang X, Tian Q, Xu J, O'Malley BW, Dong C
- Journal Title
  
  Cell reports
  
  Volume: 23 Pages: 2318-2329
- Data Source
  KAKENHI-PROJECT-16K08738
[Journal Article] Genome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation2016
- Author(s)
  Liu, X. Lu, H. Chen, T. Nallaparaju, K. C. Yan, X. Tanaka, S. Ichiyama, K. Zhang, X. Zhang, L. Wen, X. Tian, Q. Bian, X. W. Jin, W. Wei, L. Dong, C.
- Journal Title
  
  Cell reports
  
  Volume: 14 Pages: 1735-47
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860750
[Journal Article] The methylcytosine dioxygenase Tet2 promotes DNA demethylation and activation of cytokine gene expression in T cells2015
- Author(s)
  Ichiyama, K. Chen, T. Wang, X. Yan, X. Kim, B. S. Tanaka, S. Ndiaye-Lobry, D. Deng, Y. Zou, Y. Zheng, P. Tian, Q. Aifantis, I. Wei, L. Dong, C.
- Journal Title
  
  Immunity
  
  Volume: 42 Pages: 613-26
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860750
[Journal Article] CCAAT/enhancer-binding protein alpha negatively regulates IFN-gamma expression in T cells2014
- Author(s)
  Tanaka, S., Tanaka, K., Magnusson, F., Chung, Y., Martinez, G.J., Wang, Y.,Nurieva R.I., Kurosaki, T., Dong, C.
- Journal Title
  
  The journal of immunology
  
  Volume: 193 Pages: 6152-60
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26860750
[Presentation] Role of Ten-eleven translocation (Tet) in B cell self-tolerance2021
- Author(s)
  Shinya Tanaka
- Organizer
  The federation of immunological societies of Asia-Oceania (FIMSA) 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H00429
[Presentation] Role of Ten-eleven translocation (Tet) in B cell self-tolerance2021
- Author(s)
  Shinya Tanaka
- Organizer
  The federation of immunological societies of Asia-Oceania (FIMSA) 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-21H05530
[Presentation] Role of Ten-eleven translocation (Tet) in B cell self-tolerance2021
- Author(s)
  Shinya Tanaka, Wataru Ise, Tomohiro Kurosaki, Yoshihiro Baba
- Organizer
  The 50th annual meeting of the Japanese society for immunology
- Data Source
  KAKENHI-PROJECT-19K08883
[Presentation] Role of Ten-eleven translocation (Tet) in B cell self-tolerance2021
- Author(s)
  Shinya Tanaka, Wataru Ise, Tomohiro Kurosaki, Yoshihiro Baba
- Organizer
  The 50th annual meeting of the Japanese society for immunology
- Data Source
  KAKENHI-PUBLICLY-21H00429
[Presentation] Role of Ten-eleven translocation (Tet) in B cell self-tolerance2021
- Author(s)
  Shinya Tanaka, Wataru Ise, Tomohiro Kurosaki, Yoshihiro Baba
- Organizer
  The 50th annual meeting of the Japanese society for immunology
- Data Source
  KAKENHI-PUBLICLY-21H05530
[Presentation] Role of Ten-eleven translocation (Tet) in B cell self-tolerance2021
- Author(s)
  Shinya Tanaka
- Organizer
  The federation of immunological societies of Asia-Oceania (FIMSA) 2021
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08883
[Presentation] Role of Ten eleven translocation in B cell self tolerance2020
- Author(s)
  Shinya Tanaka
- Organizer
  The 15h International Symposium of the Institute Network for Biomedical Sciences
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08883
[Presentation] Ten-eleven translocation (Tet) in B cells prevents autoimmunity2019
- Author(s)
  田中伸弥
- Organizer
  日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08883
[Presentation] B cell-mediated inflammation by epigenetic regulators2018
- Author(s)
  SHINYA TANAKA
- Organizer
  2018 Fall International Convention of The Pharmaceutical Society of Korea
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08738
[Presentation] Ten-eleven translocation (Tet) demethylases mediate peripheral B cell tolerance2018
- Author(s)
  SHINYA TANAKA
- Organizer
  第47回日本免疫学会学術集会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08738
[Presentation] Ten-eleven translocation (Tet) DNA demethylases maintain peripheral B cell tolerance2018
- Author(s)
  SHINYA TANAKA
- Organizer
  第10回シグナルネットワーク研究会
- Data Source
  KAKENHI-PROJECT-16K08738
[Presentation] The regulation of Th17 differentiation by Tripartite motif-containing 33 (Trim33)2015
- Author(s)
  SHINYA TANAKA
- Organizer
  Fall international convention of the pharmaceutical society of Korea
- Place of Presentation
  Daegu, South Korea
- Year and Date
  2015-10-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860750
[Presentation] 免疫性疾患におけるCNS-2エンハンサーの重要性2008
- Author(s)
  田中伸弥
- Organizer
  京都T細胞カンファレンス(KTCC)
- Place of Presentation
  京都
- Year and Date
  2008-06-14
- Data Source
  KAKENHI-PROJECT-20790705

tanaka shinya 田中 伸弥

TANAKA SHINYA 田中 伸弥

田中 伸弥 タナカ シンヤ

Research Projects

Research Products

抗原選択的免疫応答制御を実現する為の基盤システムの構築Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

末梢自己反応性B細胞の生体恒常性維持における役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

自己反応性シンギュラリティT細胞をラベリングする新規システムの構築と動態解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

制御性B細胞を用いた物質共生制御Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The regulation of B cell tolerance by DNA demethylase, Ten-eleven translocationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The regulation of memory B cell by DNA demethylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of RANK expressed on FDCs in humoral immunityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

C/EBP alpha による液性免疫制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ゲノム情報を基盤としたアレルギーメカニズム解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Advances in Experimental Medicine and Biology (Chapter 4 of B Cell Receptor Signaling)2020

Author(s)

Publisher

Data Source

[Journal Article] Upregulated Fcrl5 disrupts B cell anergy and causes autoimmune disease2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Quiescent B Cells Acquire Sensitivity to Cell Cycle Arresting Agents by B Cell Receptor Stimulation2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Silencing and activating anergic B cells2021

Author(s)

Journal Title

DOI

tanaka shinya 田中伸弥

TANAKA SHINYA 田中伸弥

田中伸弥タナカシンヤ