WAGA Chikako 和賀央子

… Alternative Names

和賀央子ワガチカコ

Less

Researcher Number	80462795
Other IDs
Affiliation (Current)	2025: 帝京大学, 理工学部, 研究員
Affiliation (based on the past Project Information) *help	2014: 帝京大学, 理工学部, 研究員 2011 – 2013: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第二部, 科研費研究員 2012: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第二部, 科研費研究員 2010: (独)国立精神・神経医療研究センター, 神経研究所代謝研究部, 流動研究員 2007: 国立精神・神経センター, 神経研究所・代謝研究部, 研究員
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Pediatrics / Biological Sciences
Keywords	Principal Investigator 遺伝子変異 / 遺伝子検査 / 精神遅滞 / 遺伝子解析 / 網羅的遺伝子解析 / 次世代シークエンサー / 知的障害 / ターゲットシークエンス / 知的障害（精神遅滞） / ゲノム解析 … More / シナプス / X連鎖性精神遅滞 / シナプス遺伝子解析 / 広汎性発達障害 … More Except Principal Investigator 遺伝子診断 / 言語障害 / SHANK3 / 22q13.3欠失症候群 / 精神遅滞 / 自閉症 / 脳発達 / ゲノム / MeCP2 / DNAメチル化、 / エピジェネティクス / Shank3 / シナプス / 広汎性発達障害 / グルタミン酸 / カルシウム / NMDA受容体 / ATP受容体 / ニューロン / 可視化 / トランスジェニックマウス / EGFP / Iba1 / マクロファージ / 膜ラッフル / 遊走能 / P2X4受容体 / P2Y12受容体 / ケモタキシス / ATP / ミクログリア Less

Targeted capture sequence analysis and functional study of candidate genes for mental retardation and pervasive developmental disorderPrincipal Investigator
- Principal Investigator
  
  WAGA Chikako
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  Teikyo University
  独立行政法人国立精神・神経医療研究センター
Genetic and functional analysis of synaptic molecule in mental retardation and pervasive developmental disorderPrincipal Investigator
- Principal Investigator
  
  WAGA Chikako
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Center of Neurology and Psychiatry
Analysis of neuropathogenesis for autism spectrum disorders caused by mutation of SHANK3 gene.
- Principal Investigator
  
  UCHINO Shigeo
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pediatrics
- Research Institution
  National Center of Neurology and Psychiatry
ATPを介したニューロン・ミクログリア相互作用の分子基盤
- Principal Investigator
  
  高坂新一
- Project Period (FY)
  2003 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  National Center of Neurology and Psychiatry

All 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Identification of two novel Shank3 transcripts in the developing mouse neocortex.2014
- Author(s)
  Waga C, Asano H, Sanagi T, Suzuki E, Nakamura Y, Tsuchiya A, Itoh M, Goto Y, Kohsaka S, Uchino S.
- Journal Title
  
  J Neurochem.
  
  Volume: 128 Pages: 280-293
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25860896
[Journal Article] Novel variants of the SHANKS gene in Japanese autistic patients with severe delayed speech development.2011
- Author(s)
  Waga C, Okamoto N, Ondo Y, Goto Y, Kohsaka S, Uchino S
- Journal Title
  
  Psychiatr.Genet.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591239
[Journal Article] Novel variants of the SHANK3 gene in Japanese autistic patients with severe delayed speech evelopment2011
- Author(s)
  Waga C, Okamoto N, Ondo Y, Fukumura-Kato R, Goto YI, Kohsaka S, Uchino S
- Journal Title
  
  Psychiatr Genet
  
  Volume: 21(4) Issue: 4 Pages: 208-11
- DOI
  10.1097/ypg.0b013e328341e069
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23791207
[Journal Article] Inhibition of NMDA receptor activity resulted in aberrant neuronal migration caused by delayed morphological development in the mouse neocortex.2010
- Author(s)
  Uchino S, Hirasawa T, Tabata H, Gonda Y, Waga C, Ondo Y, Naka j ima K, Kohsaka S
- Journal Title
  
  Neuroscience 169
  
  Pages: 609-618
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] X連鎖性精神遅滞患者における関連遺伝子解析.2013
- Author(s)
  和賀央子，竹下絵里，中川栄二，後藤雄一
- Organizer
  Neuro2013(第35回日本神経科学大会、第56回神経化学大会、第23回日本神経回路学会大会合同年会)
- Place of Presentation
  京都国立国際会議場
- Data Source
  KAKENHI-PROJECT-25860896
[Presentation] X連鎖性が疑われる精神発達遅滞患者の候補遺伝子解析2012
- Author(s)
  和賀央子,澤野由枝,竹下絵里,中川栄二,後藤雄一
- Organizer
  日本人類遺伝学会第57回大会
- Place of Presentation
  京王プラザホテル東京
- Year and Date
  2012-10-27
- Data Source
  KAKENHI-PROJECT-23791207
[Presentation] X連鎖性が疑われる精神発達遅滞患者の候補遺伝子解析.2012
- Author(s)
  和賀央子, 澤野由枝, 竹下絵里, 中川栄二,　後藤雄一
- Organizer
  日本人類遺伝学会　第57回大会
- Place of Presentation
  東京　京王プラザホテル
- Data Source
  KAKENHI-PROJECT-23791207
[Presentation] Mutations in the SHANK3 gene in Japanese autistic patients with severe delayed speech development and mental retardation2011
- Author(s)
  Waga C, Okamoto N, Asano H, Goto YI, Uchino S, Kohsaka S
- Organizer
  The 12th International Congress of Human Genetics (ICHG) and the 61st The American Society of Human Genetics (ASHG) Annual Meeting
- Place of Presentation
  Le Palais des congres, Montreal, Canada
- Year and Date
  2011-10-13
- Data Source
  KAKENHI-PROJECT-23791207
[Presentation] 自閉症関連分子Shank3のマウス大脳皮質における新規バリアント解析.2011
- Author(s)
  和賀央子、浅野弘嗣、土屋明子、後藤雄一、伊藤雅之、内野茂夫、高坂新一
- Organizer
  第２１回臨床精神神経薬理学会・第４１回日本神経精神薬理学会
- Place of Presentation
  京王プラザホテル、東京
- Data Source
  KAKENHI-PROJECT-23791207
[Presentation] 自閉症関連遺伝子SmNK3のマウス大脳皮質発達過程におけるバリアント発現解析2011
- Author(s)
  和賀央子、浅野弘嗣、岡本伸彦、土屋明子、伊藤雅之、後藤雄一、内野茂夫、高坂新一
- Organizer
  包括脳ネットワーク夏のワークショップ
- Place of Presentation
  神戸国際会議場、兵庫
- Year and Date
  2011-08-23
- Data Source
  KAKENHI-PROJECT-23791207
[Presentation] 自閉症関連分子Shank3のマウス大脳皮質における新規バリアント解析2011
- Author(s)
  和賀央子、浅野弘嗣、土屋明子、後藤雄一、伊藤雅之、内野茂夫、高坂新一
- Organizer
  第21回臨床精神神経薬理学会・第41回日本神経精神薬理学会
- Place of Presentation
  京王プラザホテル、東京
- Year and Date
  2011-10-28
- Data Source
  KAKENHI-PROJECT-23791207
[Presentation] 自閉症関連遺伝子SHANK3のマウス大脳皮質発達過程におけるバリアント発現解析.2011
- Author(s)
  和賀央子、浅野弘嗣、岡本伸彦、土屋明子、伊藤雅之、後藤雄一、内野茂夫、高坂新一
- Organizer
  包括脳ネットワーク　夏のワークショップ
- Place of Presentation
  神戸国際会議場、兵庫
- Data Source
  KAKENHI-PROJECT-23791207
[Presentation] マウス脳発達過程における自閉症関連遺伝子SHANK3のメチル化動態解析2010
- Author(s)
  和賀央子、浅野弘嗣、加藤怜子、伊藤雅之、後藤雄一、内野茂夫、高坂新一
- Organizer
  第33回日本神経科学会・第53回日本神経化学会・第20回日本神経回路学会
- Place of Presentation
  神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] マウス脳発達過程における自閉症関連遺伝子SHANK3のメチル化動態解析2010
- Author(s)
  和賀央子, 他
- Organizer
  第33回日本神経科学会・第53回日本神経化学会・第20回日本神経回路学会
- Place of Presentation
  神戸コンベンションセンター
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] 自閉症関連遺伝子5朋N第3のマウス脳発達過程におけるメチル化動態解析およびその分子基盤に関する研究2010
- Author(s)
  和賀央子、浅野弘嗣、加藤怜子、伊藤雅之、後藤雄一、内野茂夫、高坂新一
- Organizer
  第40回日本神経精神薬理学会・第20回臨床精神神経薬理学会
- Place of Presentation
  仙台
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] 自閉症関連遺伝子SHANK3のマウス脳発達過程におけるメチル化動態解析およびその分子基盤に関する研究2010
- Author(s)
  和賀央子, 他
- Organizer
  第40回日本神経精神薬理学会・第20回臨床精神神経薬理学会
- Place of Presentation
  仙台国際センター
- Year and Date
  2010-09-16
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] Novel mutations in the SHANKS gene in autistic patients with severe delayed speech development.2009
- Author(s)
  Uchino S, Waga C, Okamoto N, Goto Y, Kohsaka S
- Organizer
  The 22nd Biennial Meeting of the International Society for Neurochemistry (ISN)/Asian Pacific Society for Neurochemistry (APSN) Joint Meeting.
- Place of Presentation
  Busan, Korea
- Year and Date
  2009-08-27
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] 自閉症患者におけるシナプス機能分子SHANK3の遺伝子解析2008
- Author(s)
  内野茂夫、和賀央子、岡本伸彦、高坂新一
- Organizer
  第51回日本神経化学会、シンポジウム「発達障害の神経化学」
- Place of Presentation
  富山
- Year and Date
  2008-09-13
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] 自閉症患者におけるシナプス機能分子SHANK3の遺伝子解析2008
- Author(s)
  和賀央子
- Organizer
  日本生化学大会・日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-20591239
[Presentation] Mutations in the SHANK3 gene in Japanese autistic patients with severe delayed speech development and mental retardation.
- Author(s)
  Waga C, Okamoto N, Asano H, Goto YI, Uchino S, Kohsaka S.
- Organizer
  The 12th International Congress of Human Genetics (ICHG) and the 61st The American Society of Human Genetics (ASHG) Annual Meeting.
- Place of Presentation
  Le Palais des congres, Montreal, Canada,
- Data Source
  KAKENHI-PROJECT-23791207

1. UCHINO Shigeo (30392434)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. GONDA Yuko (60424181)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. ITOH Masayuki (50243407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. OKAMOTO Nobuhiko (30416242)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. NAMBA Takashi (70462794)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 高坂新一 (50112686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 大澤圭子 (40392435)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 入野康宏 (10415565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 橋本学 (20415566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 奥野孝枝 (10402083)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 神鳥和代

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

WAGA Chikako 和賀 央子

和賀 央子 ワガ チカコ

Research Projects

Research Products

Co-Researchers

Targeted capture sequence analysis and functional study of candidate genes for mental retardation and pervasive developmental disorderPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic and functional analysis of synaptic molecule in mental retardation and pervasive developmental disorderPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of neuropathogenesis for autism spectrum disorders caused by mutation of SHANK3 gene.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ATPを介したニューロン・ミクログリア相互作用の分子基盤

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Identification of two novel Shank3 transcripts in the developing mouse neocortex.2014

Author(s)

Journal Title

Data Source

[Journal Article] Novel variants of the SHANKS gene in Japanese autistic patients with severe delayed speech development.2011

Author(s)

Journal Title

Data Source

[Journal Article] Novel variants of the SHANK3 gene in Japanese autistic patients with severe delayed speech evelopment2011

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of NMDA receptor activity resulted in aberrant neuronal migration caused by delayed morphological development in the mouse neocortex.2010

Author(s)

Journal Title

Data Source

[Presentation] X連鎖性精神遅滞患者における関連遺伝子解析.2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] X連鎖性が疑われる精神発達遅滞患者の候補遺伝子解析2012

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] X連鎖性が疑われる精神発達遅滞患者の候補遺伝子解析.2012

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] Mutations in the SHANK3 gene in Japanese autistic patients with severe delayed speech development and mental retardation2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 自閉症関連分子Shank3のマウス大脳皮質における新規バリアント解析.2011

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] 自閉症関連遺伝子SmNK3のマウス大脳皮質発達過程におけるバリアント発現解析2011

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 自閉症関連分子Shank3のマウス大脳皮質における新規バリアント解析2011

WAGA Chikako 和賀央子

和賀央子ワガチカコ