Hoshino Akihiro 星野顕宏

Researcher Number	80465137
Other IDs
Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 寄附講座講師
Affiliation (based on the past Project Information) *help	2024: 東京医科歯科大学, 大学院医歯学総合研究科, 寄附講座講師 2017 – 2019: 東京医科歯科大学, 大学院医歯学総合研究科, 非常勤講師
Review Section/Research Field	Principal Investigator Basic Section 49070:Immunology-related / Virology
Keywords	Principal Investigator 脱リン酸化 / リン酸化 / IKAROS / 免疫機構 / 機能解析 / ヒトヘルペスウイルス / 原発性免疫不全症 / 水痘帯状疱疹ウイルス / Epstein Barrウイルス

Identification of human IKAROS regulation system by phosphorylation and dephosphorylationPrincipal Investigator
- Principal Investigator
  
  星野顕宏
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Tokyo Medical and Dental University
Identification of the selective immune system against human herpesvirus and novel therapies developmentPrincipal Investigator
- Principal Investigator
  
  Hoshino Akihiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Tokyo Medical and Dental University

All 2020 2019 2018

All Journal Article Presentation

[Journal Article] Inherited chromosomally integrated human herpesvirus‐6 in a patient with XIAP deficiency2020
- Author(s)
  Inoue Kento、Miura Hiroki、Hoshino Akihiro、Kamiya Takahiro、Tanita Kay、Ohye Tamae、Park Myoung‐Ja、Yanagimachi Masakatsu、Takagi Masatoshi、Imai Kohsuke、Morio Tomohiro、Yoshikawa Tetsushi、Kanegane Hirokazu
- Journal Title
  
  Transplant Infectious Disease
  
  Volume: - Issue: 5
- DOI
  10.1111/tid.13331
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17692, KAKENHI-PROJECT-19K07902, KAKENHI-PROJECT-18K07814
[Journal Article] High-throughput analysis revealed the unique immunoglobulin gene rearrangements in plasmacytoma-like post-transplant lymphoproliferative disorder2020
- Author(s)
  Hoshino A, Nishimura A, Naruto T, Okano T, Matsumoto K, Okamoto K, Shintaku H, Tokoro S, Okamoto H, Wada T, Takagi M, Imai K, Kanegane H, Morio T
- Journal Title
  
  Br J Haematol
  
  Volume: - Issue: 4
- DOI
  10.1111/bjh.16583
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-17K17692
[Journal Article] Disseminated fusariosis in a child after haploidentical hematopoietic stem cell transplantation.2020
- Author(s)
  Hoshino A, Tokoro S, Akashi T, Inoue M, Takagi M, Imai K, Kanegane H, Muraosa Y, Kamei K, Morio T
- Journal Title
  
  Pediatr Int
  
  Volume: 62 Issue: 3 Pages: 419-420
- DOI
  10.1111/ped.14097
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K17692
[Journal Article] Inherited lymphoproliferative disorders2019
- Author(s)
  金兼弘和、星野顕宏
- Journal Title
  
  Rinsho Ketsueki
  
  Volume: 60 Issue: 6 Pages: 708-715
- DOI
  10.11406/rinketsu.60.708
- NAID
  130007675231
- ISSN
  0485-1439, 1882-0824
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-17K17692
[Journal Article] Hematopoietic stem cell transplantation recovers insulin deficiency in type 1 diabetes mellitus associated with IPEX syndrome2019
- Author(s)
  Yamauchi T, Takasawa K, Kamiya T, et al.
- Journal Title
  
  Pediatr Diabetes
  
  Volume: 20 Issue: 7 Pages: 1035-1040
- DOI
  10.1111/pedi.12895
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K17692
[Journal Article] Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 12019
- Author(s)
  Hoshino A, Yang X, Tanita K, Yoshida K, Ono T, Nishida N, Okuno Y, Kanzaki T, Goi K, Fujino H, Ohshima K, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Kojima S, Morio T, Kanegane H.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 143 Issue: 1 Pages: 421-424
- DOI
  10.1016/j.jaci.2018.07.044
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10099, KAKENHI-PLANNED-15H05909, KAKENHI-PROJECT-19H05656, KAKENHI-PROJECT-17K17692
[Journal Article] Epstein-Barr Virus-Associated γδ T-Cell Lymphoproliferative Disorder Associated With Hypomorphic IL2RG Mutation2019
- Author(s)
  Tanita K, Hoshino A, Imadome K, Kamiya T, Inoue K, Okano T, Yeh TW, Yanagimachi M, Shiraishi A, Ishimura M, Schober T, Rohlfs M, Takagi M, Imai K, Takada H, Ohga S, Klein C, Morio T, Kanegane H.
- Journal Title
  
  Front Pediatr
  
  Volume: 7 Pages: 15-15
- DOI
  10.3389/fped.2019.00015
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-19H03613, KAKENHI-PROJECT-17K17692, KAKENHI-PROJECT-19K08336
[Journal Article] Identification of autoantibodies using human proteome microarrays in patients with IPEX syndrome2019
- Author(s)
  Hoshino Akihiro、Kanegane Hirokazu、Nishi Masanori、Tsuge Ikuya、Tokuda Kiriko、Kobayashi Ichiro、Imai Kohsuke、Morio Tomohiro、Takagi Masatoshi
- Journal Title
  
  Clinical Immunology
  
  Volume: 203 Pages: 9-13
- DOI
  10.1016/j.clim.2019.03.011
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K17692
[Journal Article] An 18-Year-Old Male With X-linked Lymphoproliferative Syndrome Type 1 Who Developed Primary Central Nervous System Lymphoma 6 Months After Primary Epstein-Barr Virus Infection2019
- Author(s)
  Kusano N, Sakata N, Sugimoto K, et al.
- Journal Title
  
  J Pediatr Hematol Oncol
  
  Volume: 41 Issue: 8 Pages: e538-e541
- DOI
  10.1097/mph.0000000000001424
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-17K17692
[Journal Article] Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals.2018
- Author(s)
  Schwab C, Gabrysch A, Olbrich P, Patiño V, Warnatz K, Wolff D, Hoshino A, Kobayashi M, Imai K, Takagi M, Dybedal I, Haddock JA, Sansom D, Lucena JM, Seidl M, et al.
- Journal Title
  
  J Allergy Clin Immunol
  
  Volume: 印刷中
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17692
[Journal Article] High frequencies of asymptomatic Epstein-Barr virus viremia in affected and unaffected individuals with CTLA4 mutations.2018
- Author(s)
  Hoshino A, Tanita K, Kanda K, Imadome K, Shikama Y, Yasumi T, Imai K, Takagi M, Morio T, Kanegane H.
- Journal Title
  
  Clin Immunol
  
  Volume: 195 Pages: 45-48
- DOI
  10.1016/j.clim.2018.07.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K10099, KAKENHI-PROJECT-18K07814, KAKENHI-PROJECT-17K17692
[Journal Article] Dysregulation of Epstein-Barr virus infection in hypomorphic ZAP70 mutation.2018
- Author(s)
  Hoshino A, Takashima T, Yoshida K, Morimoto A, Kawahara Y, Yeh TW, Okano T, Yamashita M, Mitsuiki N, Imai K, Sakatani T, Nakazawa A, Okuno Y, Shiraishi Y, Chiba K, Tanaka H, Miyano S, Ogawa S, Kojima S, Morio T, Kanegane H.
- Journal Title
  
  J Infect Dis
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17692
[Presentation] Plasmacytoma-like post-transplant lymphoproliferative disorder with multiple autoantibodies in a XIAP deficient patient.2019
- Author(s)
  Hoshino A, Okano T, Matsumoto K, Nishimura A, Shintaku H, Tokoro S, Okamoto H, Wada T, Mitsuiki N, Kajiwara M, Takagi M, Imai K, Kanegane H, Morio T.
- Organizer
  2019 Focused Meeting of the European Society for Immunodeficiencies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17692
[Presentation] SAP欠損症（XLP1）におけるT細胞のリバータントによる免疫能の回復　－国内予後調査から－2018
- Author(s)
  星野顕宏、Xi Yang、吉田健一、小野敏明、谷田けい、西田直徳、奥野友介、神崎健仁、合井久美子、大島孝一、白石友一、千葉健一、田中洋子、宮野悟、小川誠司、小島勢二、森尾友宏、金兼弘和
- Organizer
  第27回EBV感染症研究会
- Data Source
  KAKENHI-PROJECT-17K17692

1. IMAI Kohsuke

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. 金兼弘和

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Hoshino Akihiro 星野 顕宏

Research Projects

Research Products

Co-Researchers

Identification of human IKAROS regulation system by phosphorylation and dephosphorylationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of the selective immune system against human herpesvirus and novel therapies developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Inherited chromosomally integrated human herpesvirus‐6 in a patient with XIAP deficiency2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-throughput analysis revealed the unique immunoglobulin gene rearrangements in plasmacytoma-like post-transplant lymphoproliferative disorder2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Disseminated fusariosis in a child after haploidentical hematopoietic stem cell transplantation.2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inherited lymphoproliferative disorders2019

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Hematopoietic stem cell transplantation recovers insulin deficiency in type 1 diabetes mellitus associated with IPEX syndrome2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Modification of cellular and humoral immunity by somatically reverted T cells in X-linked lymphoproliferative syndrome type 12019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Epstein-Barr Virus-Associated γδ T-Cell Lymphoproliferative Disorder Associated With Hypomorphic IL2RG Mutation2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of autoantibodies using human proteome microarrays in patients with IPEX syndrome2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An 18-Year-Old Male With X-linked Lymphoproliferative Syndrome Type 1 Who Developed Primary Central Nervous System Lymphoma 6 Months After Primary Epstein-Barr Virus Infection2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Phenotype, penetrance, and treatment of 133 CTLA-4-insufficient individuals.2018

Author(s)

Journal Title

Data Source

[Journal Article] High frequencies of asymptomatic Epstein-Barr virus viremia in affected and unaffected individuals with CTLA4 mutations.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dysregulation of Epstein-Barr virus infection in hypomorphic ZAP70 mutation.2018

Author(s)

Journal Title

Data Source

[Presentation] Plasmacytoma-like post-transplant lymphoproliferative disorder with multiple autoantibodies in a XIAP deficient patient.2019

Author(s)

Organizer

Hoshino Akihiro 星野顕宏

[Presentation] SAP欠損症（XLP1）におけるT細胞のリバータントによる免疫能の回復　－国内予後調査から－2018