Takemoto Kiwamu 竹本研

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TAKEMOTO Kiwamu 竹本研

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Researcher Number	80466432
Other IDs
Affiliation (Current)	2025: 三重大学, 医学系研究科, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 三重大学, 医学系研究科, 教授 2015 – 2017: 横浜市立大学, 医学部, 助教 2009 – 2010: Yokohama City University, 医学部, 助教
Review Section/Research Field	Principal Investigator Medium-sized Section 46:Neuroscience and related fields / Basic Section 46010:Neuroscience-general-related / Complex systems / Biological Sciences / Neurophysiology / General neuroscience / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator 光操作 / CALI法 / AMPA受容体 / 海馬記憶 / シナプス可塑性 / 神経可塑性 / 学習記憶 / 生体操作 / イメージング

in vivoにおける全タンパク質光操作技術の創生Principal Investigator
- Principal Investigator
  
  竹本研
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Challenging Research (Pioneering)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  Mie University
記憶痕跡細胞の選択・維持メカニズムに関する操作的解明Principal Investigator
- Principal Investigator
  
  竹本研
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Mie University
マルチタスクかつハイスループットな特徴を持つ光操作技術の創生Principal Investigator
- Principal Investigator
  
  竹本研
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Mie University
A technical platform for optical manipulation of synaptic moleculesPrincipal Investigator
- Principal Investigator
  
  Takemoto Kiwamu
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 46:Neuroscience and related fields
- Research Institution
  Mie University
学習前の神経回路の操作を可能にする革新的光学技術の開発Principal Investigator
- Principal Investigator
  
  竹本研
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Yokohama City University
Optical inactivation of GluA1 homomeric receptors in a single dendritic spine.Principal Investigator
- Principal Investigator
  
  TAKEMOTO Kiwamu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Yokohama City University
A light induced loss of function technology for AMPA receptorsPrincipal Investigator
- Principal Investigator
  
  TAKEMOTO Kiwamu
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Yokohama City University

All 2022 2021 2017 2016 2015 2011 2010

All Journal Article Presentation

[Journal Article] Social isolation suppresses actin dynamics and synaptic plasticity through ADF/cofilin inactivation in the developing rat barrel cortex2017
- Author(s)
  Tada H, Miyazaki T, Takemoto K, Jitsuki S, Nakajima W, Koide M, Yamamoto N, Taguchi A, Kawai H, Komiya K, Suyama K, Abe H, Sano A, Takahashi T.
- Journal Title
  
  Sci. Rep
  
  Volume: 7 Issue: 1 Pages: 8471-8471
- DOI
  10.1038/s41598-017-08849-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19951, KAKENHI-PROJECT-15K06713, KAKENHI-PROJECT-17H05062, KAKENHI-PUBLICLY-16H01278, KAKENHI-PROJECT-17H02188
[Journal Article] Optical inactivation of synaptic AMPA receptors erases fear memory.2017
- Author(s)
  K. Takemoto, H. Iwanari, H. Tada, K. Suyama, A. Sano, T. Nagai, T. Hamakubo, T. Takahashi
- Journal Title
  
  Nat Biotechnol
  
  Volume: 35 Issue: 1 Pages: 38-47
- DOI
  10.1038/nbt.3710
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24108007, KAKENHI-PROJECT-26251018, KAKENHI-PROJECT-15K15041, KAKENHI-PROJECT-15K06713, KAKENHI-PROJECT-17H05062, KAKENHI-PUBLICLY-16H01278
[Journal Article] Nogo restricts adult neural plasticity by limiting the reserve pool of synaptic AMPA receptors2016
- Author(s)
  Jitsuki S, Nakajima W, Takemoto K , Sano A, Strittmatter S and Takahashi T
- Journal Title
  
  Cereb. Cortex
  
  Volume: 26 Issue: 2 Pages: 427-439
- DOI
  10.1371/journal.pone.0149068
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06713
[Journal Article] Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage2016
- Author(s)
  Sakamaki K, Ishii TM, Sakata T, Takemoto K, Takagi C, Takeuchi A, Morishita R, Takahashi H, Nozawa A, Shinoda H, Chiba K, Sugimoto H, Saito A, Tamate S, Satou Y, Jung SK, Matsuoka S, Koyamada K, Sawasaki T, Nagai T, Ueno N
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1863 Issue: 11 Pages: 2766-2783
- DOI
  10.1016/j.bbamcr.2016.08.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04674, KAKENHI-PROJECT-16H04729, KAKENHI-PROJECT-26291019, KAKENHI-PROJECT-15K18468, KAKENHI-PUBLICLY-16H01278
[Journal Article] Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex.2016
- Author(s)
  Tada H, Miyazaki T, Takemoto K, Takase K, Jitsuki S, Nakajima W, Koide M, Yamamoto N, Komiya K, Suyama K, Sano A, Taguchi A, Takahashi T
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 113 Issue: 45
- DOI
  10.1073/pnas.1606351113
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26290025, KAKENHI-PROJECT-15K15041, KAKENHI-PROJECT-15K06713, KAKENHI-PUBLICLY-16H01278
[Journal Article] Nogo Receptor Signaling Restricts Adult Neural Plasticity by Limiting Synaptic AMPA Receptor Delivery.2016
- Author(s)
  Jitsuki S, Nakajima W, Takemoto K, Sano A, Tada H, Takahashi-Jitsuki A, Takahashi T
- Journal Title
  
  Cerebral cortex
  
  Volume: 26(1) Issue: 1 Pages: 427-439
- DOI
  10.1093/cercor/bhv232
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15041, KAKENHI-PUBLICLY-16H01278
[Journal Article] Apoptosis controls the speed of looping morphogenesis in Drosophila male terminalia2011
- Author(s)
  Kuranaga E, Matsunuma T, Kanuka H, Takemoto K, Koto A, Kimura K, Miura M
- Journal Title
  
  Development
  
  Volume: 138 Pages: 1493-1499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700412
[Journal Article] Apoptosis controls the speed of looping morphogenesis in Drosophila male terminalia2011
- Author(s)
  Kuranaga E, Matsunuma T, Kanuka H, Takemoto K, Koto A, Kimura K, Miura M
- Journal Title
  
  Development 138巻
  
  Pages: 1493-1499
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700412
[Journal Article] Serotonin mediates cross-modal reorganization of cortical circuits.2011
- Author(s)
  Jitsuki S, Takemoto K, Kawasaki T, Tada T, Takahashi A, Becamel C, Sano A, Yuzaki M, Zukin RS, Ziff EB, Kessels HW, Takahashi T.
- Journal Title
  
  Neuron 69巻
  
  Pages: 780-792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700412
[Journal Article] Serotonin mediates cross-modal reorganization of cortical circuits.2011
- Author(s)
  Jitsuki S, Takemoto K, Kawasaki T, Tada T, Takahashi A, Becamel C, Sano A, Yuzaki M, Zukin RS, Ziff EB, Kessels HW, Takahashi T.
- Journal Title
  
  Neuron
  
  Volume: 69 Pages: 780-792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700412
[Journal Article] Chromophore-assisted light inactivation of Halo Tag fusion proteins labeled with eosin in living cells2011
- Author(s)
  Takemoto K, Matsuda T, McDougall M, Klaubert D, Hasegawa A, Los G, Wood K, Miyawaki A, Nagai T
- Journal Title
  
  ACS Chem.Biol.
  
  Volume: (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700412
[Journal Article] Chromophore-assisted light inactivation of HaloTag fusion proteins labeled with eosin in living cells2011
- Author(s)
  Takemoto K, Matsuda T, McDougall M, Klaubert D, Hasegawa A, Los G, Wood K,Miyawaki A, Nagai T
- Journal Title
  
  ACS.Chem.Biol. 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21700412
[Presentation] GluA2/3 AMPA受容体複合体に対する光不活性化技術2022
- Author(s)
  實木亨、高橋琢哉、竹本研
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K19311
[Presentation] GluA2/3 AMPA受容体複合体に対する光不活性化技術2021
- Author(s)
  實木亨、高橋琢哉、竹本研
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PUBLICLY-21H00423
[Presentation] GluA2/3 AMPA受容体に対する光不活性化技術の開発と応用2021
- Author(s)
  實木亨、高橋琢哉、竹本研
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-21K19311
[Presentation] GluA2/3 AMPA受容体複合体に対する光不活性化技術2021
- Author(s)
  實木亨、高橋琢哉、竹本研
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PUBLICLY-21H00423
[Presentation] GluA2/3 AMPA受容体複合体に対する光不活性化技術2021
- Author(s)
  實木亨、高橋琢哉、竹本研
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-21K19311
[Presentation] GluA2/3 AMPA受容体に対する光不活性化技術の開発と応用2021
- Author(s)
  實木亨、高橋琢哉、竹本研
- Organizer
  第44回日本神経科学大会
- Data Source
  KAKENHI-PUBLICLY-21H00423
[Presentation] Complex-specific optical inactivation of neurotransmitter receptors for memory decoding2017
- Author(s)
  Takemoto K and Takahashi T
- Organizer
  第40回日本神経科学会
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] Complex-specific optical inactivation of neurotransmitter receptors for memory decoding2017
- Author(s)
  Takemoto K and Takahashi T
- Organizer
  第40回日本神経科学会
- Data Source
  KAKENHI-PUBLICLY-16H01278
[Presentation] タンパク質光不活化技術の開発と脳情報の解読2017
- Author(s)
  竹本研
- Organizer
  愛媛大学医学部分子病態医学セミナー
- Place of Presentation
  愛媛大学医学部(愛媛）
- Invited
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] 蛋白質機能の光不活化技術の開発と記憶情報の解読2017
- Author(s)
  竹本研
- Organizer
  東京大学大学院薬学系研究科遺伝学主催研究集会
- Place of Presentation
  湯河原研修所（神奈川）
- Invited
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] Complex-specific optical inactivation of synaptic AMPA receptors erases fear memory2017
- Author(s)
  Takemoto K and Takahashi T
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PUBLICLY-16H01278
[Presentation] Complex-specific optical inactivation of synaptic AMPA receptors erases fear memory2017
- Author(s)
  Takemoto K and Takahashi T
- Organizer
  第40回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] 複合体特異的なAMPA受容体の光不活化と恐怖記憶の消去2016
- Author(s)
  竹本研、岩成宏子、永井健治、浜窪隆雄、高橋琢哉
- Organizer
  第39回　日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川）
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] Optical inactivation of synaptic AMPA receptors for artificial memory erasure2016
- Author(s)
  Takemoto K, Iwanari H, Nagai T, Hamakubo T and Takahashi T
- Organizer
  Neuro2016
- Data Source
  KAKENHI-PUBLICLY-16H01278
[Presentation] Optical inactivation of synaptic AMPA receptors for artificial memory erasure2016
- Author(s)
  Takemoto K., Iwanari H, Nagai T, Hamakubo T and Takahashi T
- Organizer
  Neuro2016, Yokohama, 2016, Jul. 22
- Place of Presentation
  パシフィコ横浜(神奈川）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] 複合体特異的なAMPA受容体の光不活化と恐怖記憶の消去2016
- Author(s)
  竹本研、岩成宏子、永井健治、浜窪隆雄、高橋琢哉
- Organizer
  第39回　日本分子生物学会年会
- Data Source
  KAKENHI-PUBLICLY-16H01278
[Presentation] Optical inactivation of synaptic AMPA receptors erases fear memory2015
- Author(s)
  Takemoto K., Iwanari H, Nagai T, Hamakubo T and Takahashi T
- Organizer
  Neuro2015
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-07-29
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] Optical inactivation technology of synaptic AMPA receptors in vivo2015
- Author(s)
  Takemoto K., Iwanari H, Nagai T, Hamakubo T and Takahashi T
- Organizer
  Society for Neuroscience
- Place of Presentation
  Chicago (USA)
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06713
[Presentation] Light induced loss of function technology for AMPA receptors in living cells2010
- Author(s)
  Kiwamu Takemoto, Takeharu Nagai, Takuya Takahashi
- Organizer
  Neuro2010
- Place of Presentation
  神戸神戸国際展示場1号館
- Year and Date
  2010-09-03
- Data Source
  KAKENHI-PROJECT-21700412

1. AKIKO Taguchi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 竹内綾子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 松岡達

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 高橋琢哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 多田敬典

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 浜窪隆雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Takemoto Kiwamu 竹本 研

TAKEMOTO Kiwamu 竹本 研

Research Projects

Research Products

Co-Researchers

in vivoにおける全タンパク質光操作技術の創生Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

記憶痕跡細胞の選択・維持メカニズムに関する操作的解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

マルチタスクかつハイスループットな特徴を持つ光操作技術の創生Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A technical platform for optical manipulation of synaptic moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

学習前の神経回路の操作を可能にする革新的光学技術の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Optical inactivation of GluA1 homomeric receptors in a single dendritic spine.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A light induced loss of function technology for AMPA receptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Social isolation suppresses actin dynamics and synaptic plasticity through ADF/cofilin inactivation in the developing rat barrel cortex2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optical inactivation of synaptic AMPA receptors erases fear memory.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nogo restricts adult neural plasticity by limiting the reserve pool of synaptic AMPA receptors2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neonatal isolation augments social dominance by altering actin dynamics in the medial prefrontal cortex.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nogo Receptor Signaling Restricts Adult Neural Plasticity by Limiting Synaptic AMPA Receptor Delivery.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Apoptosis controls the speed of looping morphogenesis in Drosophila male terminalia2011

Author(s)

Journal Title

Takemoto Kiwamu 竹本研

TAKEMOTO Kiwamu 竹本研