SUNAYAMA Jun 砂山潤

Researcher Number	80466606
Affiliation (based on the past Project Information) *help	2013: 山形大学, 医学部, 助教 2012: 東京医科歯科大学, 難治疾患研究所, 特任助教 2008 – 2011: Yamagata University, 医学部, 助教
Review Section/Research Field	Principal Investigator Pathological medical chemistry / Experimental pathology Except Principal Investigator Cerebral neurosurgery / Biological Sciences
Keywords	Principal Investigator stemness / glioma / Keap1 / Nrf2 / 活性酸素 / UV / 放射線 / 色素幹細胞 / glioblastoma / mTOR / PI3 kinase / glioblasotma … More Except Principal Investigator … More phosphorylation / oxidative / glioma initiating cell / glioma-initiating cell / mTOR / PI3K / 造腫瘍能 / 悪性脳腫瘍 / 治療耐性 / 幹細胞 / グリオーマ / 脳腫瘍学 / 重粒子線 / がん Less

色素幹細胞の運命制御における酸化ストレス応答の役割の解明Principal Investigator
- Principal Investigator
  
  砂山潤
- Project Period (FY)
  2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Tokyo Medical and Dental University
An attempt to pioneer a new research field through fusion of studies on cancer cell energy metabolism and glioma stem cells
- Principal Investigator
  
  KITANAKA Chifumi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamagata University
Analysis of protein kinases involved in the maintenance of stemness of glioblastoma stem cellsPrincipal Investigator
- Principal Investigator
  
  SUNAYAMA Jun
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamagata University
Overcoming therapy resistance of glioma via elucidation of the mechanisms underlying glioma stem cell maintenance
- Principal Investigator
  
  KITANAKA Chifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Yamagata University
重粒子線によるがん細胞殺傷機序・治療抵抗性機序の解明とその治療応用
- Principal Investigator
  
  KITANAKA Chifumi
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Yamagata University
Search for genes involved in the maintenance of glioma stem cellsPrincipal Investigator
- Principal Investigator
  
  SUNAYAMA Jun
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pathological medical chemistry
- Research Institution
  Yamagata University

All 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK2012
- Author(s)
  Sato A, Sunayama J, Okada M, Watanabe E, Seino S, Shibuya K, Suzuki K, Narita Y, Shibui S, Kayama T, Kitanaka C
- Journal Title
  
  Stem Cells Transl Med
  
  Volume: 1 Pages: 811-824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK2012
- Author(s)
  Sato A, Sunayama J, Okada M, Watanabe E, Seino S, Shibuya K, Suzuki K, Narita Y, Shibui S, Kayama T,Kitanaka C
- Journal Title
  
  Stem Cells Transl Med
  
  Volume: 1 Pages: 811-824
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659682
[Journal Article] FoxO 3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Watanabe E, Seino S, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1327-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790305
[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011
- Author(s)
  Sato A, Sunayama J, Matsuda K, Seino S, Suzuki K, Watanabe E, Tachibana K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1942-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659682
[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Watanabe E, Seino S, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1327-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659682
[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011
- Author(s)
  Sunayama J, et al.
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1327-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790305
[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Watanabe E, Seino S, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1327-1337
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011
- Author(s)
  Sato A, Sunayama J, Matsuda K, Seino S, Suzuki K, Watanabe E, Tachibana K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 29 Pages: 1942-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790305
[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011
- Author(s)
  Sato A, Sunayama J, Matsuda K, Seino S, Suzuki K, Watanabe E, Tachibana K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  StemCells
  
  Volume: 29 Pages: 1942-1951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR.2010
- Author(s)
  Sato A, Sunayama J, Matsuda K, Tachibana K, Sakurada K, Tomiyama A, Kayama T, Kitanaka C.
- Journal Title
  
  Neurosci Lett 470
  
  Pages: 115-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790245
[Journal Article] Dual blocking of mTor and PI3K elicits a pro-differentiation effect on glioblastoma stem like-cells2010
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Neuro-Oncol
  
  Volume: 12 Pages: 1205-1219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells2010
- Author(s)
  Sunayama J, Matsuda KI, Sato A, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Stem Cells
  
  Volume: 28 Pages: 1930-1939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790305
[Journal Article] Dual blocking of mTor and PI3K elicits a pro-differentiation effect on glioblastoma stem like-cells2010
- Author(s)
  Sunayama J, Sato A, Matsuda KI, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  Neuro-Oncol
  
  Volume: 12 Pages: 1205-1219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790305
[Journal Article] Dual blocking of mTor and PI3K elicits a pro-differentiation effect on glioblastoma stem like-cells2010
- Author(s)
  Sunayama J, et al.
- Journal Title
  
  Neuro-Oncol
  
  Volume: 12 Pages: 1205-1209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015007
[Journal Article] MEK-ERK-dependent multiple caspase activation via mitochondrial proapoptotic Bcl-2 family proteins is essential for heavy ion irradiation-induced glioma celldeath2010
- Author(s)
  Tomiyama A, Tachibana K, Suzuki K, Seino S, Sunayama J, Matsuda KI, Sato A, Matsumoto Y, Nomiya T, Nemoto K, Yamashita H, Kayama T, Ando K, Kitanaka C
- Journal Title
  
  Cell Death Dis
  
  Volume: 1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR2010
- Author(s)
  Sato A, Sunayama J, Matsuda KI, Tachibana K, Sakurada K, Tomiyama A, Kayama T, Kitanaka C
- Journal Title
  
  Neurosci Lett
  
  Volume: 410 Pages: 115-120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells2010
- Author(s)
  Sunayama J, Matsuda KI, Sato A, Tachibana K, Suzuki K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Journal Title
  
  StemCells
  
  Volume: 28 Pages: 1930-1939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390402
[Journal Article] Dual blocking of mTor and P13K elicits a pro-differentiation effect on glioblastoma stem like-cells2010
- Author(s)
  Sunayama J, et al.
- Journal Title
  
  Neuro-Oncol
  
  Volume: 12 Pages: 1205-1219
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790305
[Journal Article] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the maintenance of self-renewal and tumorigenicity of glioblastoma stem-like cells2010
- Author(s)
  Sunayama J, et al.
- Journal Title
  
  Stem Cells
  
  Volume: 28 Pages: 1930-1939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20015007
[Journal Article] Downregulation of Ras C-terminal processing by JNK inhibition.2008
- Author(s)
  Mouri W, Tachibana K, Tomiyama A, Sunayama J, Sato A, Sakurada K, Kayama T, Kitanaka C.
- Journal Title
  
  Biochem Biophys Res Commun 371
  
  Pages: 273-277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20790245
[Presentation] グリオーマ幹細胞における分化誘導因子FOXO3 をターゲットとした治療法の開発2012
- Author(s)
  佐藤篤, 砂山潤, 岡田雅司, 成田善孝, 渋井壮一郎, 北中千史, 嘉山孝正
- Organizer
  第71回日本脳神経外科学会総会
- Place of Presentation
  大阪
- Year and Date
  2012-10-17
- Data Source
  KAKENHI-PROJECT-23659682
[Presentation] MEK 経路阻害によるMGMT 発現およびテモゾロミド感受性に関する検討2011
- Author(s)
  佐藤篤, 松田憲一朗, 砂山潤, 清野静香, 鈴木香, 櫻田香, 立花研, 富山新太, 北中千史, 嘉山孝正
- Organizer
  第70回日本脳神経外科学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-23659682
[Presentation] グリオーマ幹細胞における FoxO3aを介した分化と造腫瘍能の制御2011
- Author(s)
  佐藤篤,砂山潤,松田憲一朗,立花研,渡部江梨子,清野静香,鈴木香,成田善孝,渋井壮一郎,富山新太,北中千史,嘉山孝正
- Organizer
  第29回日本脳腫瘍学会学術総会
- Place of Presentation
  下呂(水明館)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] MEK inhibition enhances temozolomide sensitivity of glioma stem-like cells via MGMT down-regulation2011
- Author(s)
  Sato A, Matsuda KI, Sunayama J, Sakurada K, Tachibana K, Tomiyama A, Kitanaka C, Kayama T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-23659682
[Presentation] MEK経路阻害によるMGMT発現およびテモゾロミド感受性に関する検討2011
- Author(s)
  佐藤篤,松田憲一朗,砂山潤,清野静香,鈴木香,櫻田香,立花研,富山新太,北中千史,嘉山孝正
- Organizer
  第70回日本脳神経外科学会総会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2011-10-12
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] グリオーマ幹細胞におけるFoxO3a を介した分化と造腫瘍能の制御2011
- Author(s)
  佐藤篤, 砂山潤, 松田憲一朗, 立花研, 渡部江梨子, 清野静香, 鈴木香,成田善孝, 渋井壮一郎, 富山新太, 北中千史, 嘉山孝正
- Organizer
  第29回日本脳腫瘍学会学術総会
- Place of Presentation
  下呂
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-23659682
[Presentation] MEK inhibition enhances temozolomide sensitivity of glioma stem-like cells via MGMTdown-regulation2011
- Author(s)
  Sato A, Matsuda KI, Sunayama J, Sakurada K, Tachibana K, Tomiyama A, Kitanaka C, Kayama T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] グリオーマ幹細胞におけるFoxO3aを介した分化と造腫瘍能の制御2011
- Author(s)
  佐藤篤, 砂山潤, 松田憲一朗, 立花研, 渡部江梨子, 清野静香, 鈴木香, 成田善孝, 渋井壮一郎, 富山新太, 北中千史, 嘉山孝正
- Organizer
  第29回日本脳腫瘍学会学術総会
- Place of Presentation
  下呂(水明館)
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22790305
[Presentation] MEK inhibition enhances temozolomide sensitivity of glioma stem-like cells via MGMT down-regulation2011
- Author(s)
  Sato A, Matsuda KI, Sunayama J, Sakurada K, Tachibana K, Tomiyama A, Kitanaka C, Kayama T
- Organizer
  第70回日本癌学会学術総会
- Place of Presentation
  名古屋(名古屋国際会議場)
- Year and Date
  2011-10-03
- Data Source
  KAKENHI-PROJECT-22790305
[Presentation] グリオーマ幹細胞におけるMGMT 発現制御の分子機構に関する検討2011
- Author(s)
  佐藤篤, 松田憲一朗, 砂山潤, 清野静香, 鈴木香, 渡部江梨子, 立花研,富山新太, 北中千史, 嘉山孝正
- Organizer
  第12回日本分子脳神経外科学会
- Place of Presentation
  横浜
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23659682
[Presentation] グリオーマ幹細胞におけるMGMT発現制御の分子機構に関する検討2011
- Author(s)
  佐藤篤,松田憲一朗,砂山潤,清野静香,鈴木香,渡部江梨子,立花研,富山新太,北中千史,嘉山孝正
- Organizer
  第12回日本分子脳神経外科学会
- Place of Presentation
  横浜(パシフィコ横浜)
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] グリオーマ幹細胞におけるMGMT発現とテモゾロミド感受性に関する検討2010
- Author(s)
  佐藤篤, 松田憲一朗, 砂山潤, 清野静香, 鈴木香, 櫻田香, 立花研, 富山新太, 北中千史, 嘉山孝正
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  軽井沢(軽井沢プリンスホテル)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-22790305
[Presentation] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the regulation of stemness of glioblastoma stem cells2010
- Author(s)
  Sunayama J, et al.
- Organizer
  日本癌学会学術総会
- Place of Presentation
  大阪
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790305
[Presentation] グリオーマ幹細胞における MGMT発現とテモゾロミド感受性に関する検討2010
- Author(s)
  佐藤篤 ,松田憲一朗 ,砂山潤 ,清野静香 ,鈴木香 ,櫻田香 ,立花研 ,富山新太 ,北中千史 ,嘉山孝正
- Organizer
  第28回日本脳腫瘍学会
- Place of Presentation
  軽井沢(軽井沢プリンスホテル)
- Year and Date
  2010-11-28
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR2010
- Author(s)
  Sato A, Sunayama J, Matsuda KI, Tachibana K, Sakurada K, Tomiyama A, Kayama T, Kitanaka C
- Organizer
  The 18^<th> International Conference on Brain Tumor Research and Therapy
- Place of Presentation
  Travemuende (Gran Spa Resort Arosa Travemuende)
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21390402
[Presentation] Crosstalk between the PI3K/mTOR and MEK/ERK pathways involved in the regulation of stemness of glioblastoma stem cells2010
- Author(s)
  Sunayama J, Matsuda KI, Sato A, Tachibana K, Narita Y, Shibui S, Sakurada K, Kayama T, Tomiyama A, Kitanaka C
- Organizer
  第69回日本癌学会学術総会
- Place of Presentation
  大阪(大阪国際会議場)
- Year and Date
  2010-09-24
- Data Source
  KAKENHI-PROJECT-22790305
[Presentation] Effect of rapamycin (mTOR inhibitor) and LY294002 (PI3K inhibitor) on glioblastoma stem-like cells.2009
- Author(s)
  Sunayama J, Sato A, Matsuda K, Tachibana K, Tomiyama A, Sakurada K, Kayama T, Kitanaka C
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20790245
[Presentation] Effect of rapamycin(mTOR inhibitor)and LY294002(PI3K inhibitor)on glioblastoma stem-like cells2009
- Author(s)
  Sunayama J, et al.
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-02
- Data Source
  KAKENHI-PROJECT-20790245
[Presentation] Mechanism of heavy ion radiation-induced glioma cell death.2009
- Author(s)
  Tomiyama A, Sunayama J, Tachibana K, Matsuda K, Ando K, Kayama T, Kitanaka C
- Organizer
  第68回日本癌学会総会
- Place of Presentation
  横浜
- Year and Date
  2009-10-03
- Data Source
  KAKENHI-PROJECT-20790245
[Presentation] Isolation and characterization of cancer stem-like cells from a human glioblastoma cell line A172.2008
- Author(s)
  Sato A, Sunayama J, Sakurada K, Matsuda K, Tachibana K, Tomiyama A, Kitanaka C, Kayama T
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790245
[Presentation] Downregulation of Ras C-terminal Processing by JNK Inhibition.2008
- Author(s)
  Mouri W, Tachibana K, Tomiyama A, Sunayama J, Sato A, Sakurada K, Kayama T, Kitanaka C
- Organizer
  第67回日本癌学会総会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-20790245
[Presentation] ヒトグリオーマ細胞株A172における腫瘍幹細胞の単離・同定の試み2008
- Author(s)
  佐藤篤, 砂山潤, 松田憲一朗, 立花研, 富山新太, 櫻田香, 北中千史, 嘉山孝正
- Organizer
  第26回日本脳腫瘍学会
- Place of Presentation
  松山
- Year and Date
  2008-11-30
- Data Source
  KAKENHI-PROJECT-20790245
[Presentation] 神経幹細胞におけるc-Jun N-terminal kinase (JNK)の役割2008
- Author(s)
  佐藤篤, 砂山潤, 松田憲一郎, 立花研, 櫻田香, 北中千史, 嘉山孝正
- Organizer
  第67回日本脳神経外科学会
- Place of Presentation
  盛岡
- Data Source
  KAKENHI-PROJECT-20790245

1. KITANAKA Chifumi (70260320)

# of Collaborated Projects: 3 results

# of Collaborated Products: 21 results
2. NEMOTO Kenji (10208291)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
3. TOMIYAMA Arata (40385810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
4. TACHIBANA Ken (10400540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
5. SATO Atsushi (30455901)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

SUNAYAMA Jun 砂山 潤

Research Projects

Research Products

Co-Researchers

色素幹細胞の運命制御における酸化ストレス応答の役割の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

An attempt to pioneer a new research field through fusion of studies on cancer cell energy metabolism and glioma stem cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of protein kinases involved in the maintenance of stemness of glioblastoma stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Overcoming therapy resistance of glioma via elucidation of the mechanisms underlying glioma stem cell maintenance

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

重粒子線によるがん細胞殺傷機序・治療抵抗性機序の解明とその治療応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Search for genes involved in the maintenance of glioma stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK2012

Author(s)

Journal Title

Data Source

[Journal Article] Glioma-initiating cell elimination by metformin activation of FOXO3 via AMPK2012

Author(s)

Journal Title

Data Source

[Journal Article] FoxO 3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011

Author(s)

Journal Title

Data Source

[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011

Author(s)

Journal Title

Data Source

[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011

Author(s)

Journal Title

Data Source

[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011

Author(s)

Journal Title

Data Source

[Journal Article] FoxO3a functions as a key integrator of cellular signals that control glioblastoma stem-like cell differentiation and tumorigenicity2011

Author(s)

Journal Title

Data Source

[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011

Author(s)

Journal Title

Data Source

[Journal Article] MEK-ERK signaling dictates DNA-repair gene MGMT expression and temozolomide resistance of stem-like glioblastoma cells via the MDM2-p53 axis2011

Author(s)

Journal Title

Data Source

[Journal Article] Regulation of neural stem/progenitor cell maintenance by PI3K and mTOR.2010

Author(s)

Journal Title

Data Source

SUNAYAMA Jun 砂山潤