Yoshimoto Nobuo 良元伸男

Researcher Number	80467612
Affiliation (based on the past Project Information) *help	2015 – 2016: 大阪大学, 産業科学研究所, 特任准教授
Review Section/Research Field	Principal Investigator Cell biology
Keywords	Principal Investigator タイムラプスサイトメトリー / 全自動１細胞解析単離装置 / バイオセンサー / 嗅覚受容体レパトア / 匂い分子 / 嗅覚受容体 / 嗅覚細胞 / １細胞解析

High-throughput analysis of olfactory receptor repertoire by using the automated single-cell analysis and isolation systemPrincipal Investigator
- Principal Investigator
  
  Yoshimoto Nobuo
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  Osaka University

All 2016 2015

All Journal Article Presentation Book

[Book] バイオサイエンスとインダストリー「【解説】１細胞育種を実現する全自動1 細胞解析単離装置の開発」2016
- Author(s)
  良元伸男、黒田俊一
- Total Pages
  4
- Publisher
  バイオインダストリー協会
- Data Source
  KAKENHI-PROJECT-15K21068
[Book] AROMA RESEARCH　No.67　「特定の匂い分子に応答する嗅覚受容体群の網羅的取得法」2016
- Author(s)
  良元伸男、黒田俊一
- Total Pages
  6
- Publisher
  フレグランスジャーナル
- Data Source
  KAKENHI-PROJECT-15K21068
[Book] ファインケミカルシリーズ抗体医薬における細胞構築・培養・ダウンストリームのすべて「第５章１細胞育種を実現する全自動１細胞解析単離措置の開発」2015
- Author(s)
  良元伸男、黒田俊一
- Total Pages
  11
- Publisher
  シーエムシー出版
- Data Source
  KAKENHI-PROJECT-15K21068
[Journal Article] Bio-nanocapsules displaying various immunoglobulins as an active targeting-based drug delivery system2016
- Author(s)
  Kenji Tatematsu, Masumi Iijima, Nobuo Yoshimoto, Tadashi Nakai, Toshihide Okajima, Shun’ichi Kuroda
- Journal Title
  
  Acta Biomaterialia
  
  Volume: 35 Pages: 238-247
- DOI
  10.1016/j.actbio.2016.02.010
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K07840, KAKENHI-PROJECT-25870310, KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] RBM20 and RBM24 cooperatively promote the expression of short enh splice variants2016
- Author(s)
  Jumpei Ito, Masumi Iijima, Nobuo Yoshimoto, Tomoaki Niimi, Shun'ichi Kuroda, Andres D. Maturana
- Journal Title
  
  FEBS Letter
  
  Volume: 590 Issue: 14 Pages: 2262-2274
- DOI
  10.1002/1873-3468.12251
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16K04888
[Journal Article] Cytokine-dependent activation of the JAK-STAT pathway in Saccharomyces cerevisiae2016
- Author(s)
  Yoshimoto, N., Ikeda, Y., Tatematsu, K., Iijima, M., Nakai, T., Okajima, T., Tanizawa, K., Kuroda, S.
- Journal Title
  
  Biotechnology and Bioengineering
  
  Volume: 印刷中 Issue: 8 Pages: 1796-1804
- DOI
  10.1002/bit.25948
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870310, KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] High-throughput analysis of mammalian receptor tyrosine kinase activation in yeast cells2016
- Author(s)
  Yoshimoto N, Kuroda S
- Journal Title
  
  Methods in Molecular Biology
  
  Volume: 9999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K21068
[Journal Article] Mutational analysis of hepatitis B virus pre-S1 (9-24) fusogenic peptide2016
- Author(s)
  Qiushi Liu, Masaharu Somiya, Naohiko Shimada, Wakako Sakamoto, Nobuo Yoshimoto, Masumi Iijima, Kenji Tatematsu, Tadashi Nakai, Toshihide Okajima, Atsushi Maruyama, Shun'ichi Kuroda
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 474 Issue: 2 Pages: 406-412
- DOI
  10.1016/j.bbrc.2016.04.125
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] Cellular uptake of hepatitis B virus envelope L particles is independent of sodium taurocholate cotransporting polypeptide, but dependent on heparan sulfate proteoglycan2016
- Author(s)
  Masaharu Somiya, Qiushi Liu, Nobuo Yoshimoto, Masumi Iijima, Kenji Tatematsu, Tadashi Nakai, Toshihide Okajima, Kazuyuki Kuroki, Keiji Ueda, Shun’ichi Kuroda
- Journal Title
  
  Virology
  
  Volume: 497 Pages: 23-32
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21068
[Journal Article] High-Throughput Analysis of Mammalian Receptor Tyrosine Kinase Activation in Yeast Cells2016
- Author(s)
  Nobuo Yoshimoto, Shun'ichi Kuroda
- Journal Title
  
  Methods in Molecular Biology pp
  
  Volume: 1487 Pages: 35-52
- DOI
  10.1007/978-1-4939-6424-6_3
- ISBN
  9781493964222, 9781493964246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21068
[Journal Article] Scaffold protein enigma homolog 1 overcomes the repression of myogenesis activation by inhibitor of DNA binding 22016
- Author(s)
  Nakatani M. Ito J. Koyama R. Iijima M. Yoshimoto N. Niimi T. Kuroda S. Maturana AD
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 0 Issue: 2 Pages: 0-0
- DOI
  10.1016/j.bbrc.2016.04.119
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-14J02967, KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16K04888
[Journal Article] Bio-nanocapsule-based scaffold improves the sensitivity and ligand-binding capacity of mammalian receptors on the sensor chip2016
- Author(s)
  Iijima, M., Yoshimoto, N., Niimi, T., Maturana, A.D., Kuroda, S.
- Journal Title
  
  Biotechnology journal
  
  Volume: 印刷中 Issue: 6 Pages: 805-813
- DOI
  10.1002/biot.201500443
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25870310, KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16K04888, KAKENHI-PROJECT-16H06314
[Journal Article] Deciphering the Receptor Repertoire Encoding Specific Odorants by Time-Lapse Single-Cell Array Cytometry2016
- Author(s)
  Suzuki M, Yoshimoto N, Shimono K, Kuroda S
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Issue: 1 Pages: 19934-19934
- DOI
  10.1038/srep19934
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-16H06314
[Journal Article] Mapping the heparin-binding site of the osteoinductive protein NELL1 by site-directed mutagenesis.2015
- Author(s)
  Takahashi, K., Imai, A., Iijima, M., Yoshimoto, N., Maturana, A. D., Kuroda, S., and Niimi, T.
- Journal Title
  
  FEBS Letters
  
  Volume: 589 Issue: 24PartB Pages: 4026-4032
- DOI
  10.1016/j.febslet.2015.11.032
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350959, KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-25870310
[Journal Article] One-step scalable preparation method for non-cationic liposomes with high siRNA content2015
- Author(s)
  Somiya M, Yamaguchi K, Liu Q, Niimi T, Maturana AD, Iijima M, Yoshimoto N, Kuroda S
- Journal Title
  
  International Journal of Pharmaceutics
  
  Volume: 490 Issue: 1-2 Pages: 316-323
- DOI
  10.1016/j.ijpharm.2015.05.072
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-13J03835, KAKENHI-PROJECT-25870310
[Journal Article] Virosomes of hepatitis B virus envelope L proteins containing doxorubicin: synergistic enhancement of human liver-specific antitumor growth activity by radiotherapy2015
- Author(s)
  Liu Q, Jung J, Somiya M, Iijima M, Yoshimoto N, Niimi T, Maturana AD, Shin SH, Jeong SY, Choi EK, Kuroda S
- Journal Title
  
  International Journal of Nanomedicine
  
  Volume: 10 Pages: 4159-4172
- DOI
  10.2147/ijn.s84295
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-13J03835, KAKENHI-PROJECT-25870310
[Journal Article] Intracellular trafficking of bio-nanocapsule-liposome complex: Identification of fusogenic activity in the pre-S1 region of hepatitis B virus surface antigen L protein2015
- Author(s)
  Somiya M, Sasaki Y, Matsuzaki T, Liu Q, Iijima M, Yoshimoto N, Niimi T, Maturana AD, Kuroda S
- Journal Title
  
  Journal of Controlled Release
  
  Volume: 212 Pages: 10-18
- DOI
  10.1016/j.jconrel.2015.06.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-13J03835, KAKENHI-PROJECT-25870310
[Journal Article] Scaffold protein enigma homolog activates CREB whereas a short splice variant prevents CREB activation in cardiomyocytes2015
- Author(s)
  Ito J, Iijima M, Yoshimoto N, Niimi T, Kuroda S, Maturana AD
- Journal Title
  
  Cellular Signaling
  
  Volume: 27 Issue: 12 Pages: 2425-2433
- DOI
  10.1016/j.cellsig.2015.09.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21068, KAKENHI-PROJECT-14J02967, KAKENHI-PROJECT-25870310
[Presentation] 細胞表層FIAとイムノチャンバーを用いる１細胞育種法の開発2016
- Author(s)
  良元伸男、黒田俊一
- Organizer
  第68回日本生物工学会大会
- Place of Presentation
  富山県富山市
- Year and Date
  2016-09-28
- Data Source
  KAKENHI-PROJECT-15K21068
[Presentation] Decipherment of olfactory receptor repertoire by using an automated single-cell analysis and isolation system2016
- Author(s)
  Nobuo Yoshimoto, Masato Suzuki, Akiko Kida, Ken Shimono, Shun'ichi Kuroda
- Organizer
  The 20th ISIR International Symposium
- Place of Presentation
  大阪府大阪市
- Year and Date
  2016-12-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21068
[Presentation] ヒト化抗体高分泌CHO細胞の１細胞スクリーニング法の開発2015
- Author(s)
  木田晶子、良元伸男、黒田俊一
- Organizer
  第28回日本動物細胞工学会2015年度大会 (JAACT2015)
- Place of Presentation
  東北大学片平さくらホール（宮城県仙台市）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15K21068
[Presentation] 全自動１細胞解析単離装置を用いる１細胞育種とその応用技術2015
- Author(s)
  良元伸男、木田晶子、黒田俊一
- Organizer
  第67回日本生物工学会大会
- Place of Presentation
  城山観光ホテル（鹿児島県鹿児島市）
- Year and Date
  2015-10-26
- Data Source
  KAKENHI-PROJECT-15K21068
[Presentation] 全自動１細胞解析単離装置を用いる優良細胞の１細胞育種2015
- Author(s)
  良元伸男、木田晶子、黒田俊一
- Organizer
  第28回日本動物細胞工学会2015年度大会 (JAACT2015)
- Place of Presentation
  東北大学片平さくらホール（宮城県仙台市）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-15K21068
[Presentation] 全自動１細胞解析単離装置による１細胞育種と様々な応用成果2015
- Author(s)
  良元伸男
- Organizer
  2015年度三賞受賞者合同発表会 in BioJapan2015
- Place of Presentation
  パシフィコ横浜アネックスホール（神奈川県横浜市）
- Year and Date
  2015-10-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K21068
[Presentation] Decipherment of olfactory receptor repertoire by using an automated single-cell analysis and isolation system equipped with real-time calcium imaging device2015
- Author(s)
  Nobuo Yoshimoto
- Organizer
  Pacifichem 2015
- Place of Presentation
  Honolulu (USA)
- Year and Date
  2015-12-15
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21068

1. 立松健司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 黒田俊一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 新美友章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 飯嶋益巳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yoshimoto Nobuo 良元 伸男

Research Projects

Research Products

Co-Researchers

High-throughput analysis of olfactory receptor repertoire by using the automated single-cell analysis and isolation systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] バイオサイエンスとインダストリー「【解説】１細胞育種を実現する全自動1 細胞解析単離装置の開発」2016

Author(s)

Total Pages

Publisher

Data Source

[Book] AROMA RESEARCH No.67 「特定の匂い分子に応答する嗅覚受容体群の網羅的取得法」2016

Author(s)

Total Pages

Publisher

Data Source

[Book] ファインケミカルシリーズ 抗体医薬における細胞構築・培養・ダウンストリームのすべて「第５章 １細胞育種を実現する全自動１細胞解析単離措置の開発」2015

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Bio-nanocapsules displaying various immunoglobulins as an active targeting-based drug delivery system2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RBM20 and RBM24 cooperatively promote the expression of short enh splice variants2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytokine-dependent activation of the JAK-STAT pathway in Saccharomyces cerevisiae2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-throughput analysis of mammalian receptor tyrosine kinase activation in yeast cells2016

Author(s)

Journal Title

Data Source

[Journal Article] Mutational analysis of hepatitis B virus pre-S1 (9-24) fusogenic peptide2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cellular uptake of hepatitis B virus envelope L particles is independent of sodium taurocholate cotransporting polypeptide, but dependent on heparan sulfate proteoglycan2016

Author(s)

Journal Title

Data Source

[Journal Article] High-Throughput Analysis of Mammalian Receptor Tyrosine Kinase Activation in Yeast Cells2016

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] Scaffold protein enigma homolog 1 overcomes the repression of myogenesis activation by inhibitor of DNA binding 22016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Bio-nanocapsule-based scaffold improves the sensitivity and ligand-binding capacity of mammalian receptors on the sensor chip2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Deciphering the Receptor Repertoire Encoding Specific Odorants by Time-Lapse Single-Cell Array Cytometry2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mapping the heparin-binding site of the osteoinductive protein NELL1 by site-directed mutagenesis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] One-step scalable preparation method for non-cationic liposomes with high siRNA content2015

Yoshimoto Nobuo 良元伸男

[Book] AROMA RESEARCH　No.67　「特定の匂い分子に応答する嗅覚受容体群の網羅的取得法」2016

[Book] ファインケミカルシリーズ抗体医薬における細胞構築・培養・ダウンストリームのすべて「第５章１細胞育種を実現する全自動１細胞解析単離措置の開発」2015