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Eguchi Kohgaku  江口 工学

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… Alternative Names

江口 工学  エグチ コウガク

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Researcher Number 80470300
Other IDs
Affiliation (Current) 2025: 沖縄科学技術大学院大学, 神経活動リズムと運動遂行ユニット, シニアスタッフサイエンティスト
Affiliation (based on the past Project Information) *help 2023: 沖縄科学技術大学院大学, 神経活動リズムと運動遂行ユニット, グループリーダー
2013 – 2016: 沖縄科学技術大学院大学, 細胞分子シナプス機能ユニット, 研究員
2015: 沖縄科学技術大学院大学, 細胞分子シナプス機能ユニット, スタッフサイエンティスト
2012: 沖縄科学技術大学院大学, その他の研究科, 研究員
Review Section/Research Field
Principal Investigator
0704:Neuroscience, brain sciences, and related fields / Neurophysiology / General neuroscience / Neurophysiology and muscle physiology
Keywords
Principal Investigator
シナプス伝達 / パッチクランプ法 / 膜容量測定法 / シナプス小胞エンドサイトーシス / エンドサイトーシス / シナプス / プルキンエ細胞 / 樹状突起スパイン / シミュレーション / 代謝型グルタミン酸受容体 … More / IP3 / PIP2 / αシヌクレイン / パッチクランプ / calyx of Held / タウ / α-シヌクレイン / 微小管 / 細胞骨格 / 小胞エンドサイトーシス / RhoA / シナプス小胞 / Rhoキナーゼ / PKG Less
  • Research Projects

    (3 results)
  • Research Products

    (18 results)
  •  Computational modeling of IP3 production in neuronal dendritic spines based on the distribution pattern of PIP2 and mGluRsPrincipal Investigator

    • Principal Investigator
      江口 工学
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0704:Neuroscience, brain sciences, and related fields
    • Research Institution
      Okinawa Institute of Science and Technology Graduate University
  •  細胞骨格によるシナプス伝達制御機構の解明Principal Investigator

    • Principal Investigator
      江口 工学
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurophysiology / General neuroscience
    • Research Institution
      Okinawa Institute of Science and Technology Graduate University
  •  PKG-dependent regulation of synaptic vesicle endocytosis and its postnatal developmentPrincipal Investigator

    • Principal Investigator
      Eguchi Kohgaku
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurophysiology and muscle physiology
    • Research Institution
      Okinawa Institute of Science and Technology Graduate University

All 2016 2015 2014 2013 Other

All Journal Article Presentation

  • [Journal Article] Reconstitution of Giant Mammalian Synapses in Culture for Molecular Functional and Imaging Studies2016

    • Author(s)
      Dimitrov D., Takagi H., Guillaud L., Saitoh N., Eguchi K., and Takahashi T.
    • Journal Title

      Journal of Neuroscience

      Volume: 36(12) Issue: 12 Pages: 3600-3610

    • DOI

      10.1523/jneurosci.3869-15.2016

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Journal Article] The Regulatory Mechanisms of Vesicle Endocytosis for High-fidelity Synaptic Transmission2014

    • Author(s)
      江口工学, 高橋智幸
    • Journal Title

      Seibutsu Butsuri

      Volume: 54 Issue: 1 Pages: 015-018

    • DOI

      10.2142/biophys.54.015

    • NAID

      130003391394

    • ISSN
      0582-4052, 1347-4219
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Journal Article] Rho-Kinase Accelerates Synaptic Vesicle Endocytosis by Linking Cyclic GMP-Dependent Protein Kinase Activity to Phosphatidylinositol-4,5-Bisphosphate Synthesis2013

    • Author(s)
      Zacharie Taoufiq, Kohgaku Eguchi, Tomoyuki Takahashi
    • Journal Title

      Journal of Neuroscience

      Volume: 33(29) Issue: 29 Pages: 12099-12104

    • DOI

      10.1523/jneurosci.0730-13.2013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Journal Article] Maturation of a PKG-Dependent Retrograde Mechanism for Exoendocytic Coupling of Synaptic Vesicles2013

    • Author(s)
      Kohgaku Eguchi, Setsuko Nakanishi, Hiroshi Takagi, Zacharie Taoufiq, and Tomoyuki Takahashi
    • Journal Title

      Neuron

      Volume: 74 Issue: 3 Pages: 517-529

    • DOI

      10.1016/j.neuron.2012.03.028

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] Acute increase of a-synuclein in presynaptic terminals impairs synaptic fidelity via excessive microtubule assembly at glutamatergic synapses2016

    • Author(s)
      Eguchi K. Taoufiq Z. Takahashi T
    • Organizer
      FENS2016
    • Place of Presentation
      Copenhagen, Denmark
    • Year and Date
      2016-07-02
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18349
  • [Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission by slowing vesicle endocytosis at calyx of Held2015

    • Author(s)
      Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
    • Organizer
      The 38th Annual Meeting of Japan Neuroscience Society
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2015-07-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission at calyx of Held2015

    • Author(s)
      Eguchi K.
    • Organizer
      JSPS Core-to-Core Symposium “Mechanism of synaptic transmission"
    • Place of Presentation
      Paris, France
    • Year and Date
      2015-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18349
  • [Presentation] Acute presynaptic loading of a-syunclein impairs synaptic fidelity by slowing vesicle endocytosis at glutamatergic synapses2015

    • Author(s)
      Eguchi K., Taoufiq Z., Takahashi T.
    • Organizer
      The 45th Annual meeting of Society for Neuroscience
    • Place of Presentation
      Chicago, IL, USA
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18349
  • [Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission by slowing vesicle endocytosis at calyx of Held2015

    • Author(s)
      Eguchi K., Taoufiq Z., Takahashi T.
    • Organizer
      The 38th Annual Meeting of Japan Neuroscience Society
    • Place of Presentation
      Kobe, Japan
    • Year and Date
      2015-07-28
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K18349
  • [Presentation] Acute presynaptic loading of a-syunclein impairs synaptic fidelity by slowing vesicle endocytosis at glutamatergic synapses2015

    • Author(s)
      Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
    • Organizer
      The 45th Annual meeting of Society for Neuroscience
    • Place of Presentation
      Chicago, IL, US
    • Year and Date
      2015-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission at calyx of Held2015

    • Author(s)
      Kohgaku Eguchi
    • Organizer
      JSPS Core-to-Core Symposium “Mechanism of synaptic transmission"
    • Place of Presentation
      Paris, France
    • Year and Date
      2015-09-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] 中枢神経系シナプスにおけるシナプス小胞ダイナミクス制御機構2014

    • Author(s)
      江口工学
    • Organizer
      2014九州感覚情報処理研究会
    • Place of Presentation
      福岡, 福岡, 日本
    • Year and Date
      2014-06-28
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] A novel physiological function of Rho-kinase in synapse: Homeostasis balance of vesicle exocytosis and endocytosis by modulating phosphatidylinositol-4,5-bisphosphate2013

    • Author(s)
      Zacharie Taoufiq, Kohgaku Eguchi, Tomoyuki Takahashi
    • Organizer
      Neuroscience2013
    • Place of Presentation
      San Diego, CA, US
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] RhoA/Rhoキナーゼを介した逆行性シナプス小胞エンドサイトーシス制御機構とその役割2013

    • Author(s)
      江口工学, 高橋智幸
    • Organizer
      生理学研究所研究会 "新規シグナル伝達分子とその生理学的可能性"
    • Place of Presentation
      岡崎, 愛知, 日本
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] PKG accelerates vesicle endocytosis via Rho-associated protein kinase at the calyx of Held synapse2013

    • Author(s)
      Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
    • Organizer
      第90回日本生理学会大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] The acceleration mechanisms of synaptic endocytosis by Rho-associated protein kinase2013

    • Author(s)
      Kohgaku Eguchi
    • Organizer
      2013 JSPS Core-to-Core Program Symposium "Mechanisms of Synaptic Transmission"
    • Place of Presentation
      Kyotanabe, Kyoto, Japan
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] Rho-kinase accelerates synaptic vesicle endocytosis by modulating phosphatidylinositol-4,5-bisphosphate

    • Author(s)
      Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
    • Organizer
      9th FENS Forum of Neuroscience
    • Place of Presentation
      Milan, Italy
    • Year and Date
      2014-07-05 – 2014-07-09
    • Data Source
      KAKENHI-PROJECT-24700406
  • [Presentation] 中枢神経シナプスにおける逆行性シナプス小胞エンドサイトーシス制御機構とその役割

    • Author(s)
      江口工学
    • Organizer
      生理学研究所研究会 シナプス・神経ネットワークの機能ダイナミクス
    • Place of Presentation
      岡崎, 愛知, 日本
    • Year and Date
      2014-12-02 – 2014-12-03
    • Data Source
      KAKENHI-PROJECT-24700406

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