Eguchi Kohgaku 江口工学

… Alternative Names

江口工学エグチコウガク

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Researcher Number	80470300
Other IDs
Affiliation (Current)	2025: 沖縄科学技術大学院大学, 神経活動リズムと運動遂行ユニット, シニアスタッフサイエンティスト
Affiliation (based on the past Project Information) *help	2023: 沖縄科学技術大学院大学, 神経活動リズムと運動遂行ユニット, グループリーダー 2013 – 2016: 沖縄科学技術大学院大学, 細胞分子シナプス機能ユニット, 研究員 2015: 沖縄科学技術大学院大学, 細胞分子シナプス機能ユニット, スタッフサイエンティスト 2012: 沖縄科学技術大学院大学, その他の研究科, 研究員
Review Section/Research Field	Principal Investigator 0704:Neuroscience, brain sciences, and related fields / Neurophysiology / General neuroscience / Neurophysiology and muscle physiology
Keywords	Principal Investigator シナプス伝達 / パッチクランプ法 / 膜容量測定法 / シナプス小胞エンドサイトーシス / エンドサイトーシス / シナプス / プルキンエ細胞 / 樹状突起スパイン / シミュレーション / 代謝型グルタミン酸受容体 … More / IP3 / PIP2 / αシヌクレイン / パッチクランプ / calyx of Held / タウ / α-シヌクレイン / 微小管 / 細胞骨格 / 小胞エンドサイトーシス / RhoA / シナプス小胞 / Rhoキナーゼ / PKG Less

Research Projects
(3 results)
Research Products
(18 results)

Computational modeling of IP3 production in neuronal dendritic spines based on the distribution pattern of PIP2 and mGluRsPrincipal Investigator
- Principal Investigator
  
  江口工学
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
細胞骨格によるシナプス伝達制御機構の解明Principal Investigator
- Principal Investigator
  
  江口工学
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  Okinawa Institute of Science and Technology Graduate University
PKG-dependent regulation of synaptic vesicle endocytosis and its postnatal developmentPrincipal Investigator
- Principal Investigator
  
  Eguchi Kohgaku
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurophysiology and muscle physiology
- Research Institution
  Okinawa Institute of Science and Technology Graduate University

All 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Reconstitution of Giant Mammalian Synapses in Culture for Molecular Functional and Imaging Studies2016
- Author(s)
  Dimitrov D., Takagi H., Guillaud L., Saitoh N., Eguchi K., and Takahashi T.
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 36(12) Issue: 12 Pages: 3600-3610
- DOI
  10.1523/jneurosci.3869-15.2016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700406
[Journal Article] The Regulatory Mechanisms of Vesicle Endocytosis for High-fidelity Synaptic Transmission2014
- Author(s)
  江口工学, 高橋智幸
- Journal Title
  
  Seibutsu Butsuri
  
  Volume: 54 Issue: 1 Pages: 015-018
- DOI
  10.2142/biophys.54.015
- NAID
  130003391394
- ISSN
  0582-4052, 1347-4219
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700406
[Journal Article] Rho-Kinase Accelerates Synaptic Vesicle Endocytosis by Linking Cyclic GMP-Dependent Protein Kinase Activity to Phosphatidylinositol-4,5-Bisphosphate Synthesis2013
- Author(s)
  Zacharie Taoufiq, Kohgaku Eguchi, Tomoyuki Takahashi
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 33(29) Issue: 29 Pages: 12099-12104
- DOI
  10.1523/jneurosci.0730-13.2013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700406
[Journal Article] Maturation of a PKG-Dependent Retrograde Mechanism for Exoendocytic Coupling of Synaptic Vesicles2013
- Author(s)
  Kohgaku Eguchi, Setsuko Nakanishi, Hiroshi Takagi, Zacharie Taoufiq, and Tomoyuki Takahashi
- Journal Title
  
  Neuron
  
  Volume: 74 Issue: 3 Pages: 517-529
- DOI
  10.1016/j.neuron.2012.03.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] Acute increase of a-synuclein in presynaptic terminals impairs synaptic fidelity via excessive microtubule assembly at glutamatergic synapses2016
- Author(s)
  Eguchi K. Taoufiq Z. Takahashi T
- Organizer
  FENS2016
- Place of Presentation
  Copenhagen, Denmark
- Year and Date
  2016-07-02
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18349
[Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission by slowing vesicle endocytosis at calyx of Held2015
- Author(s)
  Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
- Organizer
  The 38th Annual Meeting of Japan Neuroscience Society
- Place of Presentation
  Kobe, Japan
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission at calyx of Held2015
- Author(s)
  Eguchi K.
- Organizer
  JSPS Core-to-Core Symposium “Mechanism of synaptic transmission"
- Place of Presentation
  Paris, France
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18349
[Presentation] Acute presynaptic loading of a-syunclein impairs synaptic fidelity by slowing vesicle endocytosis at glutamatergic synapses2015
- Author(s)
  Eguchi K., Taoufiq Z., Takahashi T.
- Organizer
  The 45th Annual meeting of Society for Neuroscience
- Place of Presentation
  Chicago, IL, USA
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18349
[Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission by slowing vesicle endocytosis at calyx of Held2015
- Author(s)
  Eguchi K., Taoufiq Z., Takahashi T.
- Organizer
  The 38th Annual Meeting of Japan Neuroscience Society
- Place of Presentation
  Kobe, Japan
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18349
[Presentation] Acute presynaptic loading of a-syunclein impairs synaptic fidelity by slowing vesicle endocytosis at glutamatergic synapses2015
- Author(s)
  Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
- Organizer
  The 45th Annual meeting of Society for Neuroscience
- Place of Presentation
  Chicago, IL, US
- Year and Date
  2015-10-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission at calyx of Held2015
- Author(s)
  Kohgaku Eguchi
- Organizer
  JSPS Core-to-Core Symposium “Mechanism of synaptic transmission"
- Place of Presentation
  Paris, France
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] 中枢神経系シナプスにおけるシナプス小胞ダイナミクス制御機構2014
- Author(s)
  江口工学
- Organizer
  2014九州感覚情報処理研究会
- Place of Presentation
  福岡, 福岡, 日本
- Year and Date
  2014-06-28
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] A novel physiological function of Rho-kinase in synapse: Homeostasis balance of vesicle exocytosis and endocytosis by modulating phosphatidylinositol-4,5-bisphosphate2013
- Author(s)
  Zacharie Taoufiq, Kohgaku Eguchi, Tomoyuki Takahashi
- Organizer
  Neuroscience2013
- Place of Presentation
  San Diego, CA, US
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] RhoA/Rhoキナーゼを介した逆行性シナプス小胞エンドサイトーシス制御機構とその役割2013
- Author(s)
  江口工学, 高橋智幸
- Organizer
  生理学研究所研究会 "新規シグナル伝達分子とその生理学的可能性"
- Place of Presentation
  岡崎, 愛知, 日本
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] PKG accelerates vesicle endocytosis via Rho-associated protein kinase at the calyx of Held synapse2013
- Author(s)
  Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
- Organizer
  第90回日本生理学会大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] The acceleration mechanisms of synaptic endocytosis by Rho-associated protein kinase2013
- Author(s)
  Kohgaku Eguchi
- Organizer
  2013 JSPS Core-to-Core Program Symposium "Mechanisms of Synaptic Transmission"
- Place of Presentation
  Kyotanabe, Kyoto, Japan
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] Rho-kinase accelerates synaptic vesicle endocytosis by modulating phosphatidylinositol-4,5-bisphosphate
- Author(s)
  Kohgaku Eguchi, Zacharie Taoufiq, Tomoyuki Takahashi
- Organizer
  9th FENS Forum of Neuroscience
- Place of Presentation
  Milan, Italy
- Year and Date
  2014-07-05 – 2014-07-09
- Data Source
  KAKENHI-PROJECT-24700406
[Presentation] 中枢神経シナプスにおける逆行性シナプス小胞エンドサイトーシス制御機構とその役割
- Author(s)
  江口工学
- Organizer
  生理学研究所研究会　シナプス・神経ネットワークの機能ダイナミクス
- Place of Presentation
  岡崎, 愛知, 日本
- Year and Date
  2014-12-02 – 2014-12-03
- Data Source
  KAKENHI-PROJECT-24700406

Eguchi Kohgaku 江口 工学

江口 工学 エグチ コウガク

Research Projects

Research Products

Computational modeling of IP3 production in neuronal dendritic spines based on the distribution pattern of PIP2 and mGluRsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞骨格によるシナプス伝達制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PKG-dependent regulation of synaptic vesicle endocytosis and its postnatal developmentPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Reconstitution of Giant Mammalian Synapses in Culture for Molecular Functional and Imaging Studies2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Regulatory Mechanisms of Vesicle Endocytosis for High-fidelity Synaptic Transmission2014

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Rho-Kinase Accelerates Synaptic Vesicle Endocytosis by Linking Cyclic GMP-Dependent Protein Kinase Activity to Phosphatidylinositol-4,5-Bisphosphate Synthesis2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Maturation of a PKG-Dependent Retrograde Mechanism for Exoendocytic Coupling of Synaptic Vesicles2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Acute increase of a-synuclein in presynaptic terminals impairs synaptic fidelity via excessive microtubule assembly at glutamatergic synapses2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission by slowing vesicle endocytosis at calyx of Held2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission at calyx of Held2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Acute presynaptic loading of a-syunclein impairs synaptic fidelity by slowing vesicle endocytosis at glutamatergic synapses2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Excess α-synuclein impairs the fidelity of synaptic transmission by slowing vesicle endocytosis at calyx of Held2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] Acute presynaptic loading of a-syunclein impairs synaptic fidelity by slowing vesicle endocytosis at glutamatergic synapses2015

Author(s)

Organizer

Place of Presentation

Year and Date

Eguchi Kohgaku 江口工学

江口工学エグチコウガク