Doi Kento 土井研人

… Alternative Names

DOI KENT 土井研人

DOI Kent 土井研人

Less

Researcher Number	80505892
Other IDs
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 東京大学, 医学部附属病院, 教授 2020: 東京大学, 医学部附属病院, 准教授 2012 – 2018: 東京大学, 医学部附属病院, 講師 2016: 東京大学, 医学部附属病院, 特任講師 2014: 東京大学, 医学部附属病院, 助教 2010 – 2012: 東京大学, 医学部附属病院, 助教 2009 – 2010: 東京大学, 医学部附属病院, 特任助教
Review Section/Research Field	Principal Investigator Kidney internal medicine / Basic Section 55060:Emergency medicine-related Except Principal Investigator Basic Section 55060:Emergency medicine-related / Basic Section 55050:Anesthesiology-related / Emergency medicine / Kidney internal medicine
Keywords	Principal Investigator 急性腎障害 / 敗血症 / 腎臓学 / 炎症 / 交感神経 / 多臓器不全 / 心腎連関症候群 / 慢性腎臓病 / アポトーシス / 心筋障害 … More / 遠隔臓器障害 / ミトコンドリア / 心腎連関 / 好中球活性化 / 急性肺傷害 / 肺腎連関 / 臓器連関 / 盲腸結紮穿刺腹膜炎モデル / L-FABP / バイオマーカー / 急性腎不全 / 敗血症性急性腎不全 … More Except Principal Investigator 敗血症 / 免疫抑制 / リモデリング / 虚血再灌流 / 重症感染 / 免疫賦活 / 生体防御 / 一次免疫機能 / 虚血再灌流障害 / 重症感染症 / PAI-1 / 播種性血管内凝固 / ICU / 集中治療医 / TITIN / エコー / 集中治療 / 筋肉 / ICU-AW / PICS / バイオマーカー / 院内感染症 / 急性腎障害 / ゲノム医科学 / ヘパラン硫酸 / 腎臓病学 / 蛋白尿 / ヘパラン硫酸プロテオグリカン / HLA / ゲノム解析 / 糖尿病性腎症 / 膜性腎症 / ネフローゼ症候群 Less

敗血症におけるplasminogen activator inhibitor-1阻害の効果検証
- Principal Investigator
  
  早川峰司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Hokkaido University
Role of sympathetic nerve activation in sepsisPrincipal Investigator
- Principal Investigator
  
  土井研人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  The University of Tokyo
Elucidation of Mechanisms of Innate Immune Suppression in Critical Illness and Optimization of Immunomodulatory Therapy
- Principal Investigator
  
  内田寛治
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55050:Anesthesiology-related
- Research Institution
  The University of Tokyo
Analysis of muscle injury in severe condition focusing on TITIN
- Principal Investigator
  
  中村謙介
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Yokohama City University
  Teikyo University
Protection and organ injury by angiotensin II treatment for septic shockPrincipal Investigator
- Principal Investigator
  
  DOI KENT
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  The University of Tokyo
Renal injury progression after acute kidney injuryPrincipal Investigator
- Principal Investigator
  
  Doi Kent
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Mechanism of severe sepsis associated with hospital acquired infection
- Principal Investigator
  
  NAKAJIMA Susumu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Emergency medicine
- Research Institution
  The University of Tokyo
Kidney-Heart crosstalk and mitochondria injury in acute kidney injuryPrincipal Investigator
- Principal Investigator
  
  Doi Kent
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Elucidation to Pathogenetic Mechanism of Nephrotic Proteinuria through Genetic and Functional Analysis
- Principal Investigator
  
  NOIRI Eisei
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
Role of Toll-like receptor 4 in kidney-lung crosstalkPrincipal Investigator
- Principal Investigator
  
  DOI Kent
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo
L-type fatty acid-binding protein in septic acute kidney injuryPrincipal Investigator
- Principal Investigator
  
  DOI Kent
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  The University of Tokyo

All 2016 2015 2014 2013 2012 2011 2010 2009 Other

All Journal Article Presentation Patent

[Journal Article] Impact of acute kidney injury on distant organ function: recent findings and potential therapeutic targets.2016
- Author(s)
  Kent Doi, Hamid Rabb
- Journal Title
  
  Kidney International
  
  Volume: 89 Issue: 3 Pages: 555-564
- DOI
  10.1016/j.kint.2015.11.019
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461211
[Journal Article] Hamman syndrome: pneumomediastinum combined with hyperosmolar hyperglycemic state.2016
- Author(s)
  Hirayama I, Hiruma T, Ueda Y, Doi K, Nakajima S.
- Journal Title
  
  The American Journal of Emergency Medicine
  
  Volume: 34 Issue: 10 Pages: 2058-2058
- DOI
  10.1016/j.ajem.2016.03.039
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H06176, KAKENHI-PROJECT-26462747
[Journal Article] Regulation of Mitochondrial Dynamics by Dynamin-Related Protein-1 in Acute Cardiorenal Syndrome.2015
- Author(s)
  Maki Sumida, Kent Doi, Emi Ogasawara, Tetsushi Yamashita, Yoshifumi Hamasaki, Taro Kariya, Eiki Takimoto, Naoki Yahagi, Masaomi Nangaku and Eisei Noiri
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 26 Issue: 10 Pages: 2378-2387
- DOI
  10.1681/asn.2014080750
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25461211
[Journal Article] Regulation of Mitochondrial Dynamics by Dynamin-Related Protein-1 in Acute Cardiorenal Syndrome.2015
- Author(s)
  Sumida M, Doi K, Ogasawara E, Yamashita T, Hamasaki Y, Kariya T, Takimoto E, Yahagi N, Nangaku M, Noiri E.
- Journal Title
  
  J Am Soc Nephrol.
  
  Volume: 26
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390212
[Journal Article] The high-mobility group protein B1-Toll-like receptor 4 pathway contributes to the acute lung injury induced by bilateral nephrectomy.2014
- Author(s)
  Doi K, Ishizu T, Tsukamoto-Sumida M, Hiruma T, Yamashita T, Ogasawara E, Hamasaki Y, Yahagi N, Nangaku M, Noiri E.
- Journal Title
  
  Kidney Int
  
  Volume: 85 Issue: 2 Pages: 1000-1010
- DOI
  10.1038/ki.2014.62
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390212
[Journal Article] siRNA Delivery Targeting to the Lung via Agglutination-Induced Accumulation and Clearance of Cationic Tetraamino Fullerene2014
- Author(s)
  K. Minami, K. Okamoto, K. Doi, K. Harano, E. Noiri, E. Nakamura
- Journal Title
  
  Sci. Rep.
  
  Volume: 4 Issue: 1 Pages: 4916-4916
- DOI
  10.1038/srep04916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22000008, KAKENHI-PROJECT-24390212
[Journal Article] Protection of glucagon-like peptide-1 in cisplatin-induced renal injury elucidates gut-kidney connection.2013
- Author(s)
  Katagiri D, Hamasaki Y, Doi K, Okamoto K, Negishi K, Nangaku M, Noiri E
- Journal Title
  
  J Am Soc Nephrol
  
  Volume: 24 Issue: 12 Pages: 2034-2043
- DOI
  10.1681/asn.2013020134
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390212
[Journal Article] Mild elevation of urinary biomarkers in prerenal acute kidney injury2012
- Author(s)
  Doi K, et al.
- Journal Title
  
  Kidney International
  
  Volume: 82 Issue: 10 Pages: 1114-20
- DOI
  10.1038/ki.2012.266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390212
[Journal Article] Evaluation of new acute kidney injury biomarkers in a mixed intensive care unit2011
- Author(s)
  Doi K, et al
- Journal Title
  
  Critical Care Medicine
  
  Volume: 39 Pages: 2464-2469
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Journal Article] Lung injury following acute kidney injury: kidney-lung crosstalk2011
- Author(s)
  Doi K, Ishizu T, Fujita T, Noiri E.
- Journal Title
  
  Clin Exp Nephrol.
  
  Volume: 15 Pages: 464-470
- NAID
  10029571491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790931
[Journal Article] Evaluation of new acute kidney injury biomarkers in a mixed intensive care unit2011
- Author(s)
  Doi K, Negishi K, Ishizu T, Katagiri D, Fujita T, Matsubara T, Yahagi N, Sugaya T, Noiri E.
- Journal Title
  
  Crit Care Med.
  
  Volume: 39 Pages: 2464-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Journal Article] Urinary L-type fatty acid-binding protein as a new biomarker of sepsis complicated with acute kidney injury2010
- Author(s)
  Doi K, Noiri E, Maeda-Mamiya R, Ishii T, Negishi K, Hamasaki Y, Fujita T, Yahagi N, Koide H, Sugaya T, Nakamura T.
- Journal Title
  
  Crit Care Med.
  
  Volume: 38 Pages: 2037-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Journal Article] Urinary L-type fatty acid-binding protein as a new renal biomarker in critical care.2010
- Author(s)
  Doi K, Noiri E, Sugaya T.
- Journal Title
  
  Current Opinion Critical Care.
  
  Volume: 16 Pages: 545-549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Journal Article] Urinary L-type fatty acid-binding protein as a new renal biomarker in critical care2010
- Author(s)
  Doi K, Noiri E, Sugaya T.
- Journal Title
  
  Curr Opin Crit Care
  
  Volume: 16 Pages: 545-549
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Journal Article] Urinary L-type fatty acid-binding protein as a new biomarker of sepsis complicated with acute kidney injury2010
- Author(s)
  Doi K, et al
- Journal Title
  
  Critical Care Medicine
  
  Volume: 38 Pages: 2037-2042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Journal Article] Urinary L-type fatty acid-binding protein as a new biomarker of sepsis complicated with acute kidney injury.2010
- Author(s)
  Doi K, Noiri E, Maeda-Mamiya R, Ishii T, Negishi K, Hamasaki Y, Fujita T, Yahagi N, Koide H, Sugaya T, Nakamura T.
- Journal Title
  
  Critical Care Medicine
  
  Volume: 38 Pages: 2037-2042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Journal Article] HMGB-1-TLR4 pathway contributes to acute lung injury induced by bilateral nephrectomy
- Author(s)
  Kent Doi, Tomoko Ishizu, Emi Ogasawara, Yoshifumi Hamasaki, Naoki Yahagi, Masaomi Nangaku, Eisei Noiri
- Volume
  (投稿中)
- Data Source
  KAKENHI-PROJECT-23790931
[Journal Article] Mild elevation of urinary biomarkers in pre-renal acute kidney injury
- Author(s)
  Doi K, Katagiri D, Negishi K, Hasegawa S, Hamasaki Y, Fujita T, Matsubara T, Ishii T, Yahagi N, Sugaya T, Noiri E
- Journal Title
  
  Kidney Int
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790795
[Patent] 敗血症又は多臓器不全の予後診断方法及び予後診断用キット2010
- Inventor(s)
  菅谷健、野入英世、土井研人
- Industrial Property Rights Holder
  国立大学法人東京大学
- Filing Date
  2010-07-15
- Overseas
- Data Source
  KAKENHI-PROJECT-21790795
[Presentation] Animal models for progression from acute to chronic kidney injury in mice2016
- Author(s)
  Kengo Mayumi, Mizuki Yamano, Tetsushi Yamashita, Yoshifumi Hamasaki, Eisei Noiri, Masaomi Nangaku, Kent Doi
- Organizer
  American Society of Nephrology
- Place of Presentation
  Chicago, USA
- Year and Date
  2016-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09603
[Presentation] Sulfatase 2, Identified By Genome Association Analysis, Contributes to Protection against Nephrotic Syndrome2014
- Author(s)
  Kenjiro Honda, MD, PhD, Koji Okamoto, MD, PhD, Kent Doi, MD, PhD, FASN, Masaomi Nangaku, MD, PhD, Katsushi Tokunaga, Eisei Noiri, MD, PhD, FASN
- Organizer
  米国腎臓学会
- Place of Presentation
  フィラデルフィア会議場
- Year and Date
  2014-11-15
- Data Source
  KAKENHI-PROJECT-24390212
[Presentation] Evaluation of urinary L-FABP as an AKI biomarker in mixed ICU2010
- Author(s)
  Doi K, Negishi K, Ishii T, Fujita T, Matsubara T, Yahagi N, Sugaya T, Noiri E.
- Organizer
  American Society of Nephrology 2010 Annual Meeting
- Place of Presentation
  米国・コロラド
- Year and Date
  2010-11-20
- Data Source
  KAKENHI-PROJECT-21790795
[Presentation] ICU急性腎障害における尿中L型脂肪酸結合蛋白(L-FABP)測定の意義2010
- Author(s)
  土井, 他
- Organizer
  第107回日本内科学会講演会
- Place of Presentation
  東京
- Year and Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21790795
[Presentation] Comparison of urinary L-FABP with NGAL and IL-18 in an adult heterogeneous ICU population2010
- Author(s)
  Doi K, et al.
- Organizer
  米国腎臓学会年次総会
- Place of Presentation
  東京
- Year and Date
  2010-04-09
- Data Source
  KAKENHI-PROJECT-21790795
[Presentation] Evaluation of urinary L-FABP as an AKI biomarker in mixed ICU2009
- Author(s)
  Doi K, et al.
- Organizer
  米国腎臓学会年次総会
- Place of Presentation
  米国(サンディエゴ)
- Year and Date
  2009-10-30
- Data Source
  KAKENHI-PROJECT-21790795
[Presentation] Role of Toll-like receptor 4 and HMGB-1 in kidney-lung crosstalk Kent Doi
- Author(s)
  Kent Doi, Tomoko Ishizu, Emi Ogasawara, Yoshifumi Hamasaki, Naoki Yahagi, Masaomi Nangaku, Eisei Noiri
- Organizer
  米国腎臓学会2013 年学術集会
- Data Source
  KAKENHI-PROJECT-23790931

1. NOIRI Eisei (00301820)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
2. YAHAGI Naoki (60158045)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 内田寛治 (60302709)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. TOKUNAGA Katsushi (40163977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. OKAMOTO Koji (80572247)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. HAMASAKI Yoshifumi (20617774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. NEGISHI Kosuke (40572219)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. NAKAJIMA Susumu (40323597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HIRUMA Takahiro (40572277)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 小宮山雄介 (90586471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中村謙介 (50466760)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 下條信威 (20462210)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 山川一馬 (50597507)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 東條健太郎 (80737552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 早川峰司 (10374282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 宮田敏男 (10222332)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 工藤大介 (30455844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 星野耕大 (40762266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 土田拓見 (50838654)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Matsuura Ryo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. Yamashita Tetsushi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
22. OKAMOTO Toshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 浜崎敬文

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
24. 中村栄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Doi Kento 土井 研人

DOI KENT 土井 研人

DOI Kent 土井 研人

Research Projects

Research Products

Co-Researchers

敗血症におけるplasminogen activator inhibitor-1阻害の効果検証

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of sympathetic nerve activation in sepsisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of Mechanisms of Innate Immune Suppression in Critical Illness and Optimization of Immunomodulatory Therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of muscle injury in severe condition focusing on TITIN

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Protection and organ injury by angiotensin II treatment for septic shockPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Renal injury progression after acute kidney injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of severe sepsis associated with hospital acquired infection

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Kidney-Heart crosstalk and mitochondria injury in acute kidney injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation to Pathogenetic Mechanism of Nephrotic Proteinuria through Genetic and Functional Analysis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of Toll-like receptor 4 in kidney-lung crosstalkPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

L-type fatty acid-binding protein in septic acute kidney injuryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Impact of acute kidney injury on distant organ function: recent findings and potential therapeutic targets.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Hamman syndrome: pneumomediastinum combined with hyperosmolar hyperglycemic state.2016

Author(s)

Journal Title

Doi Kento 土井研人

DOI KENT 土井研人

DOI Kent 土井研人