Yuasa Mari 湯浅磨里

Researcher Number	80506303
Other IDs
Affiliation (Current)	2025: 国立健康危機管理研究機構, 国立感染症研究所品質管理研究センター, 主任研究員
Affiliation (based on the past Project Information) *help	2018 – 2020: 東京医科歯科大学, 生体材料工学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator 創薬化学 / エピジェネティクス / レチノイド / 核内受容体

Development of Novel Cell Regulation Technology targeting Nuclear ReceptorsPrincipal Investigator
- Principal Investigator
  
  Yuasa Mari
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Tokyo Medical and Dental University

All 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Activation of β2-adrenergic receptor signals suppresses mesenchymal phenotypes of oral squamous cell carcinoma cells.2021
- Author(s)
  Sakakitani S, Podyma-Inoue KA, Takayama R, Takahashi K, Ishigami-Yuasa M, Kagechika H, Harada H, Watabe T.
- Journal Title
  
  Cancer Sci
  
  Volume: 112 Issue: 1 Pages: 155-167
- DOI
  10.1111/cas.14670
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K10145, KAKENHI-PROJECT-20K10111, KAKENHI-PROJECT-20J11926, KAKENHI-PROJECT-17K11828, KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-20H03851
[Journal Article] Chemical Screening of Nuclear Receptor Modulators2020
- Author(s)
  Ishigami-Yuasa Mari、Kagechika Hiroyuki
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 15 Pages: 5512-5512
- DOI
  10.3390/ijms21155512
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06572
[Journal Article] Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore2020
- Author(s)
  Koga, H.; Negishi, M.; Kinoshita, M.; Fujii, S.; Mori, S.; Ishigami-Yuasa, M.; Kawachi, E.; Kagechika, H.; Tanatani, A.
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 15 Pages: 5584-5584
- DOI
  10.3390/ijms21155584
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K06963, KAKENHI-PROJECT-19K22486, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-18K06572
[Journal Article] Class IIb HDAC Inhibition Enhances the Inhibitory Effect of Am80, a Synthetic Retinoid, in Prostate Cancer2019
- Author(s)
  Ishigami-Yuasa Mari、Ekimoto Hisao、Kagechika Hiroyuki
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 3 Pages: 448-452
- DOI
  10.1248/bpb.b18-00782
- NAID
  130007606238
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06572
[Journal Article] Chemical compounds that suppress hypoxia-induced stress granule formation enhance cancer drug sensitivity of human cervical cancer HeLa cells2018
- Author(s)
  Timalsina Shikshya、Arimoto-Matsuzaki Kyoko、Kitamura Masami、Xu Xiaoyin、Wenzhe Qiu、Ishigami-Yuasa Mari、Kagechika Hiroyuki、Hata Yutaka
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 164 Issue: 5 Pages: 381-391
- DOI
  10.1093/jb/mvy062
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-16K19029
[Journal Article] Efficient high-throughput screening by ER Ca2+measurement to identify inhibitors of ryanodine receptor Ca2+-release channels2018
- Author(s)
  Murayama Takashi、Kurebayashi Nagomi、Ikegami-Yuasa Mari、Mori Shuichi、Suzuki Yukina、Akima Ryunosuke、Ogawa Haruo、Suzuki Junji、Kanemaru Kazunori、Oyamada Hideto、Kiuchi Yuji、Iino Masamitsu、Kagechika Hiroyuki、Sakurai Takashi
- Journal Title
  
  Molecular Pharmacology
  
  Volume: - Issue: 1 Pages: 722-730
- DOI
  10.1124/mol.117.111468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08243, KAKENHI-PLANNED-25117002, KAKENHI-PROJECT-16K08507, KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-16H04667, KAKENHI-PROJECT-25221304
[Journal Article] Structure-activity relationship of novel (benzoylaminophenoxy)phenol derivatives as anti-prostate cancer agents2018
- Author(s)
  Kazui Yuko、Fujii Shinya、Yamada Ayumi、Ishigami-Yuasa Mari、Kagechika Hiroyuki、Tanatani Aya
- Journal Title
  
  Bioorganic & Medicinal Chemistry
  
  Volume: 26 Issue: 18 Pages: 5118-5127
- DOI
  10.1016/j.bmc.2018.09.008
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-17H03997, KAKENHI-PROJECT-16K08318
[Journal Article] Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models.2018
- Author(s)
  Shimada S, Akiyama Y, Mogushi K, Ishigami-Yuasa M, Kagechika H, Nagasaki H, Fukamachi H, Yuasa Y, Tanaka S.
- Journal Title
  
  British Journal of Cancer
  
  Volume: - Issue: 7 Pages: 972-984
- DOI
  10.1038/s41416-018-0008-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H02670, KAKENHI-PROJECT-16K08647, KAKENHI-PROJECT-18K06572, KAKENHI-PROJECT-18K19575
[Presentation] ヒト前立腺がん細胞におけるタミバロテンとヒストン脱アセチル化酵素阻害薬の併用効果の検討および作用機序の解明2020
- Author(s)
  湯浅磨里、影近弘之
- Organizer
  第79回日本癌学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] nhibitory effect of a synthetic retinoid, tamibarotene in combination with epigenetic drugs on human cancer cell growth.2019
- Author(s)
  Mari Ishigami-Yuasa, Hiroyuki Kagechika
- Organizer
  第78回日本癌学会学術総会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] 前立腺がんLNCapにおける合成レチノイドAm80とクラス選択的ヒストン脱アセチル化酵素阻害剤の併用効果.2019
- Author(s)
  湯浅磨里, 影近弘之
- Organizer
  第23回日本がん分子標的治療学会学術集会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] エピジェネティック阻害薬との併用効果2019
- Author(s)
  湯浅磨里, 影近弘之.
- Organizer
  第361回脂溶性ビタミン総合研究委員会
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] Growth inhibition of several human cancer cell lines by a synthetic retinoid in combination with the epigenetic modulators.2018
- Author(s)
  Ishigami-Yuasa M
- Organizer
  JSPS Core-to-core Program Symposium Frontier of Genomic Medicine “Retinoid (Am80, Tamibarotene) as therapeutics for intractable diseases”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] Growth inhibition of AML cell lines by a synthetic retinoid in combination with the epigenetic modulators, and protein level of RARα.2018
- Author(s)
  Ishigami-Yuasa M, Kagechika H.
- Organizer
  FASEB The 4th International Conference on Retinoids
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] Search for type 2 ryanodine receptor inhibitor by monitoring endoplasmic reticulum Ca2+.2018
- Author(s)
  Tamura M, Kurebayashi N, Murayama T, Mori S, Ishigami-Yuasa M, Kagechika H, Suzuki J, Kanemaru K, Iino M, Sakurai T.
- Organizer
  BSP18 62ND Annual Meeting Biophysical Society
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] 変異１型リアノジン受容体のCa2+遊離を抑制する新規化合物の創製.2018
- Author(s)
  森修一、飯沼大翔、間中紀暁、湯浅磨里、村山尚、呉林なごみ、影近弘之.
- Organizer
  日本薬学会第138年会
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] Discovery of novel RyR2 inhibitors as candidates for anti-arrhythmic drugs.2018
- Author(s)
  Tamura M, Kurebayashi N, Murayama T, Mori S, Ishigami-Yuasa M, Kagechika H, Suzuki J, Kanemaru K, Iino M, Sakurai T.
- Organizer
  WCP 2018 KYOTO 18 th WORLD CONGRESS OF BASIC AND CLINICAL PHARMACOLOGY
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] Development of WNK Signaling Inhibitors as a New Class of Antihypertensive Drugs.2018
- Author(s)
  Ishigami-Yuasa M, Watanabe Y, Suzuyama H, Masuno H, Fujii S, Mori T, Kikuchi E, Uchida S, Kagechika H.
- Organizer
  SPS Core-to-core Program Symposium Frontier of Genomic Medicine “Retinoid (Am80, Tamibarotene) as therapeutics for intractable diseases”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K06572
[Presentation] 急性骨髄性白血病細胞株Kasumi-1における Am80（タミバロテン）とヒストン脱アセチル化酵素阻害薬との併用効果.2018
- Author(s)
  湯浅磨里, 影近弘之
- Organizer
  第22回日本がん分子標的治療学会学術集会
- Data Source
  KAKENHI-PROJECT-18K06572

1. MURAYAMA takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 棚谷綾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 国広なごみ

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 原田浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 秋山好光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 田中真二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 深町博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 島田周

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yuasa Mari 湯浅 磨里

Research Projects

Research Products

Co-Researchers

Development of Novel Cell Regulation Technology targeting Nuclear ReceptorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Activation of β2-adrenergic receptor signals suppresses mesenchymal phenotypes of oral squamous cell carcinoma cells.2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chemical Screening of Nuclear Receptor Modulators2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Development of Androgen-Antagonistic Coumarinamides with a Unique Aromatic Folded Pharmacophore2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Class IIb HDAC Inhibition Enhances the Inhibitory Effect of Am80, a Synthetic Retinoid, in Prostate Cancer2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] Chemical compounds that suppress hypoxia-induced stress granule formation enhance cancer drug sensitivity of human cervical cancer HeLa cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficient high-throughput screening by ER Ca2+measurement to identify inhibitors of ryanodine receptor Ca2+-release channels2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structure-activity relationship of novel (benzoylaminophenoxy)phenol derivatives as anti-prostate cancer agents2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of selective inhibitors for diffuse-type gastric cancer cells by screening of annotated compounds in preclinical models.2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] ヒト前立腺がん細胞におけるタミバロテンとヒストン脱アセチル化 酵素阻害薬の併用効果の検討および作用機序の解明2020

Author(s)

Organizer

Data Source

[Presentation] nhibitory effect of a synthetic retinoid, tamibarotene in combination with epigenetic drugs on human cancer cell growth.2019

Author(s)

Organizer

Data Source

[Presentation] 前立腺がんLNCapにおける合成レチノイドAm80とクラス選択的ヒストン脱アセチル化酵素阻害剤の併用効果.2019

Author(s)

Organizer

Data Source

[Presentation] エピジェネティック阻害薬との併用効果2019

Author(s)

Organizer

Data Source

[Presentation] Growth inhibition of several human cancer cell lines by a synthetic retinoid in combination with the epigenetic modulators.2018

Author(s)

Organizer

Data Source

[Presentation] Growth inhibition of AML cell lines by a synthetic retinoid in combination with the epigenetic modulators, and protein level of RARα.2018

Author(s)

Organizer

Data Source

[Presentation] Search for type 2 ryanodine receptor inhibitor by monitoring endoplasmic reticulum Ca2+.2018

Author(s)

Yuasa Mari 湯浅磨里

[Presentation] ヒト前立腺がん細胞におけるタミバロテンとヒストン脱アセチル化酵素阻害薬の併用効果の検討および作用機序の解明2020