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Okura Tsuyoshi  大倉 毅

… Alternative Names

大倉 毅  オオクラ ツヨシ

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Researcher Number 80510073
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-3713-6617
Affiliation (Current) 2025: 鳥取大学, 医学部, 講師
Affiliation (based on the past Project Information) *help 2018 – 2023: 鳥取大学, 医学部, 講師
2014 – 2017: 鳥取大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 52010:General internal medicine-related / Laboratory medicine / Metabolomics
Except Principal Investigator
Basic Section 48030:Pharmacology-related
Keywords
Principal Investigator
糖尿病 / インスリン抵抗性 / エキソソーム / 2型糖尿病 / エクソソーム / インスリン抵抗性指標 / グルコースクランプ
Except Principal Investigator
髄鞘 / 視床下部 / レプチン / 肥満
  • Research Projects

    (6 results)
  • Research Products

    (23 results)
  • Co-Researchers

    (11 People)
  •  視床下部髄鞘異常による肥満でのレプチン抵抗性発症の機序と肥満病態への寄与の解明

    • Principal Investigator
      市原 克則
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Tottori University
  •  エクソソーム解析によるインスリン抵抗性の分子病態の解明Principal Investigator

    • Principal Investigator
      大倉 毅
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Tottori University
  •  Research for the novel therapeutic target of insulin resistance and type 2 diabetes by analyzing of exosomePrincipal Investigator

    • Principal Investigator
      OKURA Tsuyoshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Tottori University
  •  Research for the molecular mechanism of insulin resistance in the Japanese and American by analyzing of exosomePrincipal Investigator

    • Principal Investigator
      OKURA Tsuyoshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
    • Review Section
      Basic Section 52010:General internal medicine-related
    • Research Institution
      Tottori University
  •  Development of a novel insulin resistance index that is minimally affected by hepatic insulin clearancePrincipal Investigator

    • Principal Investigator
      OKURA Tsuyoshi
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory medicine
    • Research Institution
      Tottori University
  •  a novel insulin resistance index for the patients with type 2 diabetesPrincipal Investigator

    • Principal Investigator
      Okura Tsuyoshi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Metabolomics
    • Research Institution
      Tottori University

All 2024 2023 2022 2020 2018 2017 2016 2015 Other

All Journal Article Presentation

  • [Journal Article] Presurgery health influences outcomes following vertical sleeve gastrectomy in adolescents2024

    • Author(s)
      Swertfeger Debi、Kim Ahlee、Sexmith Hannah、Moreno‐Fernandez Maria E.、Davidson W. Sean、Helmrath Michael、Jenkins Todd、Okura Tsuyoshi、Geh Esmond、Xanthakos Stavra A.、Szabo Sara、Nakamura Takahisa、Divanovic Senad、Shah Amy Sanghavi
    • Journal Title

      Obesity

      Volume: 32 Issue: 6 Pages: 1-11

    • DOI

      10.1002/oby.24018

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07443
  • [Journal Article] Aldehyde dehydrogenase 2 polymorphism is an important gene for insulin resistance in Japanese patients with type 2 diabetes.2023

    • Author(s)
      Okura T, Nakamura R, Anno M, Ito Y, Kitao S, Endo S, Taneda N, Matsumoto K, Shoji K, Okura H, Matsuzawa K, Izawa S, Ueta E, Kato M, Imamura T, Taniguchi SI, Yamamoto K.
    • Journal Title

      Metabol Open.

      Volume: 18 Pages: 100242-100242

    • DOI

      10.1016/j.metop.2023.100242

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H03378, KAKENHI-PROJECT-22K07443
  • [Journal Article] Fasting hepatic insulin clearance reflects postprandial hepatic insulin clearance: a brief report2023

    • Author(s)
      Okura Tsuyoshi、Nakamura Risa、Kitao Sonoko、Ito Yuichi、Anno Mari、Matsumoto Kazuhisa、Shoji Kyoko、Matsuzawa Kazuhiko、Izawa Shoichiro、Okura Hiroko、Ueta Etsuko、Kato Masahiko、Imamura Takeshi、Taniguchi Shin-ichi、Yamamoto Kazuhiro
    • Journal Title

      Diabetology & Metabolic Syndrome

      Volume: 15 Issue: 1 Pages: 01241-4

    • DOI

      10.1186/s13098-023-01241-4

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07443
  • [Journal Article] Significance of pancreatic duodenal homeobox-1 (PDX-1) genetic polymorphism in insulin secretion in Japanese patients with type 2 diabetes2022

    • Author(s)
      Okura Tsuyoshi、Nakamura Risa、Ito Yuichi、Kitao Sonoko、Anno Mari、Endo Satomi、Taneda Natsuka、Matsumoto Kazuhisa、Shoji Kyoko、Okura Hiroko、Matsuzawa Kazuhiko、Izawa Shoichiro、Ueta Etsuko、Kato Masahiko、Imamura Takeshi、Taniguchi Shin-ichi、Yamamoto Kazuhiro
    • Journal Title

      BMJ Open Diabetes Research and Care

      Volume: 10 Issue: 5 Pages: e002908-e002908

    • DOI

      10.1136/bmjdrc-2022-002908

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07443, KAKENHI-PROJECT-19H03378
  • [Journal Article] Hepatic insulin clearance is increased in patients with high HbA1c type 2 diabetes: a preliminary report2020

    • Author(s)
      Okura Tsuyoshi、Fujioka Yohei、Nakamura Risa、Anno Mari、Ito Yuichi、Kitao Sonoko、Matsumoto Kazuhisa、Shoji Kyoko、Sumi Keisuke、Matsuzawa Kazuhiko、Izawa Shoichiro、Okura Hiroko、Ueta Etsuko、Noma Hisashi、Kato Masahiko、Imamura Takeshi、Taniguchi Shin-Ichi、Yamamoto Kazuhiro
    • Journal Title

      BMJ Open Diabetes Research & Care

      Volume: 8 Issue: 1 Pages: e001149-e001149

    • DOI

      10.1136/bmjdrc-2019-001149

    • NAID

      120007146973

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07913, KAKENHI-PROJECT-19KK0402, KAKENHI-PROJECT-17K00753
  • [Journal Article] CPR-IR is an insulin resistance index that is minimally affected by hepatic insulin clearance?A preliminary research2018

    • Author(s)
      Okura Tsuyoshi、Nakamura Risa、Fujioka Yohei、Kawamoto-Kitao Sonoko、Ito Yuichi、Matsumoto Kazuhisa、Shoji Kyoko、Sumi Keisuke、Matsuzawa Kazuhiko、Izawa Shoichiro、Ueta Etsuko、Kato Masahiko、Imamura Takeshi、Taniguchi Shin-ichi、Yamamoto Kazuhiro
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 5 Pages: 0197663-0197663

    • DOI

      10.1371/journal.pone.0197663

    • NAID

      120007146977

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Journal Article] Body mass index ?23 is a risk factor for insulin resistance and diabetes in Japanese people: A brief report2018

    • Author(s)
      Okura Tsuyoshi、Nakamura Risa、Fujioka Yohei、Kawamoto-Kitao Sonoko、Ito Yuichi、Matsumoto Kazuhisa、Shoji Kyoko、Sumi Keisuke、Matsuzawa Kazuhiko、Izawa Shoichiro、Ueta Etsuko、Kato Masahiko、Imamura Takeshi、Taniguchi Shin-ichi、Yamamoto Kazuhiro
    • Journal Title

      PLOS ONE

      Volume: 13 Issue: 7 Pages: 0201052-0201052

    • DOI

      10.1371/journal.pone.0201052

    • NAID

      120007146974

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Journal Article] グルコースクランプ法を用いた新規インスリン抵抗性指標の開発2018

    • Author(s)
      大倉毅
    • Journal Title

      Bio Clinica

      Volume: 31 Pages: 466-468

    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Journal Article] 肝インスリン分解の影響を受けにくい新規インスリン抵抗性指標CPR‐IRの開発2018

    • Author(s)
      大倉毅
    • Journal Title

      Bio Clinica

      Volume: 33

    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Journal Article] Serum fatty acid-binding protein 4 (FABP4) concentration is associated with insulin resistance in peripheral tissues, A clinical study.2017

    • Author(s)
      Nakamura R, Okura T, Fujioka Y, Sumi K, Matsuzawa K, Izawa S, Ueta E, Kato M, Taniguchi SI, Yamamoto K.
    • Journal Title

      PLoS One

      Volume: 12 Issue: 6 Pages: e0179737-e0179737

    • DOI

      10.1371/journal.pone.0179737

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Journal Article] High serum advanced glycation end products are associated with decreased insulin secretion in patients with type 2 diabetes2017

    • Author(s)
      Tsuyoshi Okura, Etsuko Ueta, Risa Nakamura, Yohei Fujioka, Keisuke Sumi, Kazuhisa matsumoto, Kyoko Shoji, Kazuhiko Matsuzawa, Shoichiro Izawa, Yuri Nomi, Hitomi Mihara, Yuzuru Otsuka, Masahiko Kato, Shin-ichi Taniguchi, Kazuhiro Yamamoto
    • Journal Title

      Journal of Diabetes Research

      Volume: 印刷中

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Journal Article] High Serum Advanced Glycation End Products Are Associated with Decreased Insulin Secretion in Patients with Type 2 Diabetes: A Brief Report2017

    • Author(s)
      Okura Tsuyoshi、Ueta Etsuko、Nakamura Risa、Fujioka Yohei、Sumi Keisuke、Matsumoto Kazuhisa、Shoji Kyoko、Matsuzawa Kazuhiko、Izawa Shoichiro、Nomi Yuri、Mihara Hitomi、Otsuka Yuzuru、Kato Masahiko、Taniguchi Shin-ichi、Yamamoto Kazuhiro
    • Journal Title

      Journal of Diabetes Research

      Volume: 2017 Pages: 1-7

    • DOI

      10.1155/2017/5139750

    • NAID

      120007146981

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K00892, KAKENHI-PROJECT-16K08935, KAKENHI-PROJECT-15K16195
  • [Journal Article] 2型糖尿病における新規インスリン抵抗性指標の開発2016

    • Author(s)
      大倉 毅
    • Journal Title

      BIO Clinica

      Volume: 31 Pages: 87-89

    • Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Presentation] SGLT2阻害薬の食後インスリン動態、インスリン抵抗性に与える影響の検証2023

    • Author(s)
      大倉 毅、北尾 苑子、伊藤 祐一、阿武 茉利、市原 克則、今村 武史、山本 一博
    • Organizer
      第44回日本臨床薬理学会学術総会
    • Data Source
      KAKENHI-PROJECT-22K06860
  • [Presentation] 日本人2型糖尿病のインスリン分泌・抵抗性に関与する因子の検討2023

    • Author(s)
      9.大倉 毅, 北尾 苑子, 伊藤 祐一, 阿武 茉利, 中村 理沙, 上田 悦子, 今村 武史, 谷口 晋一, 山本 一博
    • Organizer
      第66回日本糖尿病学会年次学術集会
    • Data Source
      KAKENHI-PROJECT-22K07443
  • [Presentation] 肝インスリン分解に影響する因子の検討2018

    • Author(s)
      大倉 毅、藤岡 洋平、中村 理沙、谷口 晋一、山本 一博
    • Organizer
      第5回肝臓と糖尿病・代謝研究会
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Presentation] Hepatic Insulin Clearance Is Increased in the Patients with Poorly Controlled Type 2 Diabetes2018

    • Author(s)
      Okura T, Annno M, Ito Y
    • Organizer
      American Diabetes Association 78th Scientific Sessions
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Presentation] 肝インスリン分解の影響を受けにくい血中Cペプチドを用いた新規インスリン抵抗性指標の開発2016

    • Author(s)
      大倉 毅, 藤岡 洋平, 中西 理沙, 角 啓佑, 松本 和久,庄司 恭子, 松澤 和彦, 伊澤 正一郎, 加藤 雅彦, 谷口 晋一, 山本 一博
    • Organizer
      第59回日本糖尿病学会年次学術集会
    • Place of Presentation
      国立京都国際会館(京都府京都市)
    • Year and Date
      2016-05-19
    • Data Source
      KAKENHI-PROJECT-16K08935
  • [Presentation] 20/(fasting C-peptide × fasting plasma glucose) is a novel index of insulin resistance with small effect of hepatic insulin clearance2015

    • Author(s)
      Tsuyoshi Okura
    • Organizer
      American Diabetes Association 75th Scientific Sessions
    • Place of Presentation
      Boston Convention and Exhibition Center(アメリカ、ボストン)
    • Year and Date
      2015-06-05
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26870373
  • [Presentation] グルコースクランプ試験結果推定式,新規インスリン抵抗性指標1080/(空腹時Cペプチド×空腹時血糖)の開発2015

    • Author(s)
      大倉 毅
    • Organizer
      第112 回日本内科学会講演会
    • Place of Presentation
      みやこめっせ(京都市)
    • Year and Date
      2015-04-10
    • Data Source
      KAKENHI-PROJECT-26870373
  • [Presentation] 肝インスリン代謝の影響の少ない新規インスリン抵抗性指標の開発2015

    • Author(s)
      大倉 毅
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      海峡メッセ下関(下関市)
    • Year and Date
      2015-05-21
    • Data Source
      KAKENHI-PROJECT-26870373
  • [Presentation] 肝インスリン代謝の影響の少ない新規インスリン抵抗性指標の開発

    • Author(s)
      大倉 毅
    • Organizer
      第58回日本糖尿病学会年次学術集会
    • Place of Presentation
      東京第一ホテル下関(下関市)
    • Year and Date
      2015-05-21 – 2015-05-23
    • Data Source
      KAKENHI-PROJECT-26870373
  • [Presentation] 20/(fasting C-peptide × fasting plasma glucose) is a novel index of insulin resistance with small effect of hepatic insulin clearance

    • Author(s)
      Tsuyoshi Okura
    • Organizer
      American Diabetes Association’s 75th Scientific Sessions
    • Place of Presentation
      Boston, Massachusetts, USA
    • Year and Date
      2015-06-05 – 2015-06-09
    • Data Source
      KAKENHI-PROJECT-26870373
  • 1.  藤岡 洋平 (10791048)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 2.  NAKAMURA Risa
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 3.  市原 克則 (50710711)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  長田 佳子 (50304209)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  SUMI keisuke
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  UETA Etsuko
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  IMAMURA Takeshi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  OTSUKA Yuzuru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  NOMI Yuri
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  MIHARA Hitomi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  伊藤 靖
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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