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KIKUCHI SHOHEI  菊地 尚平

… Alternative Names

Kikuchi Shohei  菊地 尚平

KIKUCHI Shohei  菊地 尚平

菊池 尚平  キクチ ショウヘイ

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Researcher Number 80515792
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-0961-6253
Affiliation (Current) 2025: 富山大学, 学術研究部医学系, 講師
2025: 札幌医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 富山大学, 学術研究部医学系, 特命助教
2016 – 2021: 札幌医科大学, 医学部, 助教
2020: 富山大学, 附属病院, 特命助教
2014: 札幌医科大学, 医学部, 助教
2009 – 2011: 札幌医科大学, 医学部, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Hematology
Except Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Hematology / Basic Section 54010:Hematology and medical oncology-related / Basic Section 53010:Gastroenterology-related / Gastroenterology
Keywords
Principal Investigator
IAP阻害剤 / アポトーシス / 多発性骨髄腫 / IAP / ●血液腫瘍 / アポトーシス誘導 / HDAC阻害剤
Except Principal Investigator
白血病 / 骨髄異形成症候群 / CAR-NK … More / CAR-T / CD26 / 分子標的薬 / Hck / DPP9 / 治療開発 / バイオマーカー / 血液悪性腫瘍 / 阻害剤 / DPP8 / 骨髄リプログラミング / エクソソーム / リプログラミング / PD-MSC / YAP1 / iPS細胞 / 急性骨髄性白血病 / PCBP1 / STK4 / HIPPO / miR-7977 / マイクロRNA / 骨髄間葉系幹細胞 / 細胞外小胞 / 薬物搬送 / 治療 / 相乗効果 / ヒストン脱アセチル化酵素 / 化学療法 / 肝細胞癌 / ● / 膵がん / エピジェネティクス / FOXO3a / 細胞周期 / 細胞周期停止 / 膵癌 / HDAC阻害剤 / 腫瘍幹細胞 / ゲノム / 予後因子 / 活性酸素 / HPLC-ECD / 幹細胞 / 鉄キレート剤 / 酸化的DNA損傷 / 鉄キレート / 8-OHdG / MDS / 発現制御 / 臨床 / シグナル伝達 / 内科 / 癌 Less
  • Research Projects

    (9 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (15 People)
  •  T細胞性血液がんのCD26を標的とする新たな遺伝子改変がん免疫療法の開発

    • Principal Investigator
      佐藤 勉
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      University of Toyama
  •  Development of the treatment for hematologic malignancies using a novel DPP8 inhibitor and identification of biomarkers

    • Principal Investigator
      Sato Tsutomu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      University of Toyama
  •  Analysis of the development and pathogenesis of AML/MDS via extracellular vesicles

    • Principal Investigator
      Kobune Masayoshi
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Sapporo Medical University
  •  Simultaneous XIAP and cIAP1/2 inhibition by AZD5582 induces apoptosis in multiple myelomaPrincipal Investigator

    • Principal Investigator
      Kikuchi Shohei
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      University of Toyama
      Sapporo Medical University
  •  Development of novel treatment for liver cancer with class-selective HDAC inhibitors

    • Principal Investigator
      Miyanishi Koji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53010:Gastroenterology-related
    • Research Institution
      Sapporo Medical University
  •  HDAC inhibition against pancreatic cancer

    • Principal Investigator
      Michihiro Ono
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Gastroenterology
    • Research Institution
      Sapporo Medical University
  •  selective HDAC class IIa inhibition against myelomaPrincipal Investigator

    • Principal Investigator
      Kikuchi Shohei
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University
  •  Establishment of iron chelation therapy to inhibit the development of MDS

    • Principal Investigator
      KOBUNE Masayoshi
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University
  •  Development of dual targeting therapy for cancer stem cells and niche

    • Principal Investigator
      KOBUNE Masayoshi
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Hematology
    • Research Institution
      Sapporo Medical University

All 2023 2021 2020 2019 2014 2012 2010 Other

All Journal Article Presentation

  • [Journal Article] DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies2023

    • Author(s)
      Kikuchi S, Wada A, Kamihara Y, Okazaki K, Jawaid P, Rehman MU, Kobayashi E, Susukida T, Minemura T, Nabe Y, Iwao N, Ozawa T, Hatano R, Yamada M, Kishi H, Matsuya Y, Mizuguchi M, Hayakawa Y, Dang NH, Sakamoto Y, Morimoto C, Sato T
    • Journal Title

      Cells

      Volume: 12 Issue: 7 Pages: 1100-1100

    • DOI

      10.3390/cells12071100

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21K18261, KAKENHI-PROJECT-23K06501, KAKENHI-PROJECT-21K07237, KAKENHI-PROJECT-21H02782, KAKENHI-PROJECT-23K27395, KAKENHI-PROJECT-23K27423
  • [Journal Article] Possible clinical outcomes using early enteral nutrition in individuals with allogeneic hematopoietic stem cell transplantation: A single-center retrospective study2021

    • Author(s)
      Satoshi Iyama, Hiroomi Tatsumi, Tsukasa Shiraishi, Shohei Kikuchi, Tsutomu Sato, Hirofumi Ohnishi, Shin-Ichi Yokota, Masayoshi Kobune
    • Journal Title

      Nutrition

      Volume: 83 Pages: 111093-111093

    • DOI

      10.1016/j.nut.2020.111093

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K23921, KAKENHI-PROJECT-19K08871
  • [Journal Article] Diffuse large B cell lymphoma with HIV infection presented with disseminated thromboembolism during antiretroviral therapy2020

    • Author(s)
      池田 博、井山 諭、加藤 淳二、小船 雅義、長島 加奈、藤田 千紗、後藤 亜香利、堀口 拓人、菊地 尚平、村瀬 和幸、高田 弘一
    • Journal Title

      Rinsho Ketsueki

      Volume: 61 Issue: 11 Pages: 1595-1599

    • DOI

      10.11406/rinketsu.61.1595

    • NAID

      130007951912

    • ISSN
      0485-1439, 1882-0824
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08871
  • [Journal Article] EPO-R+ myelodysplastic cells with ring sideroblasts produce high erythroferrone levels to reduce hepcidin expression in hepatic cells2019

    • Author(s)
      Miura, S. Kobune, M. Horiguchi, H. Kikuchi, S. Iyama, S. Murase, K. Goto, A. Ikeda, H. Takada, K. Miyanishi, K. Kato, J.
    • Journal Title

      Blood Cells Mol Dis

      Volume: 78 Pages: 1-8

    • DOI

      10.1016/j.bcmd.2019.04.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08871
  • [Journal Article] miR-7977 inhibits the Hippo-YAP signaling pathway in bone marrow mesenchymal stromal cells2019

    • Author(s)
      Yoshida, M. Horiguchi, H. Kikuchi, S. Iyama, S. Ikeda, H. Goto, A. Kawano, Y. Murase, K. Takada, K. Miyanishi, K. Kato, J. Kobune, M.
    • Journal Title

      PLoS One

      Volume: 14 Issue: 3 Pages: e0213220-e0213220

    • DOI

      10.1371/journal.pone.0213220

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08871
  • [Journal Article] Narrowband ultraviolet B phototherapy ameliorates acute graft-versus-host disease by a mechanism involving in vivo expansion of CD4+CD25+Foxp3+ regulatory T cells.2014

    • Author(s)
      Iyama S,Murase K,Sato T,Hashimoto A,Tatekoshi A,Horiguchi H,Kamihara Y,Ono K,Kikuchi S,Takada K,Kawano Y,Hayashi T,Miyanishi K,Sato Y,Takimoto R,Kobune M,Mori S,Kato J,Yamashita T,Kato J.
    • Journal Title

      Int J Hematol

      Volume: 99 Issue: 4 Pages: 471-476

    • DOI

      10.1007/s12185-014-1530-1

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24591427, KAKENHI-PROJECT-24659466, KAKENHI-PROJECT-25461705
  • [Journal Article] A novel strategy inducing autophagic cell death in Burkitt’s lymphoma cells with anti-CD19-targeted liposomal rapamycin.2014

    • Author(s)
      Ono K, Sato T, Iyama S, Tatekoshi A, Hashimoto A, Kamihara Y, Horiguchi H, Kikuchi S, Kawano Y,Takada K, Hayashi T, Miyanishi K, Sato Y, Takimoto R, Kobune M, Kato J.
    • Journal Title

      Blood Cancer J

      Volume: 7 Issue: 2 Pages: e180-e180

    • DOI

      10.1038/bcj.2014.2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24591403, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659466
  • [Journal Article] Improvement of iron-mediated oxidative DNA damage in patients with transfusion-dependent myelodysplastic syndrome by treatment with deferasirox.2012

    • Author(s)
      Kikuchi S, Kobune M, Iyama S, Sato T, Murase K, Kawano Y, Takada K, Ono K, Kaneko Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
    • Journal Title

      Free Radic Biol Med

      Volume: 23(6) Issue: 4 Pages: 548-550

    • DOI

      10.1016/j.freeradbiomed.2012.06.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24590985, KAKENHI-PROJECT-24659466
  • [Journal Article] Prognostic significance of serum-ferritin level at diagnosis in myelodysplastic syndrome2012

    • Author(s)
      Kobune M, et al. 2^<nd>
    • Journal Title

      Int J Hematol

      Volume: (In press) Issue: 5 Pages: 527-534

    • DOI

      10.1007/s12185-012-1048-3

    • NAID

      10030633185

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21591213, KAKENHI-PROJECT-23890169, KAKENHI-PROJECT-24659372, KAKENHI-PROJECT-24659466
  • [Presentation] 骨髄異形成症候群を増悪させる環境因子の解析2014

    • Author(s)
      小船雅義,堀口拓人,定免渉,菊地尚平,村瀬和幸,井山 諭,高田弘一,
    • Organizer
      第56回日本血液科学会秋季北海道地方会シンポジウム
    • Place of Presentation
      北海道大学(北海道, 札幌市)
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-24659466
  • [Presentation] SMO阻害剤は急性骨髄性白血病細胞の薬剤耐性を解除する2010

    • Author(s)
      小船雅義, 村瀬和幸, 井山諭, 佐藤勉, 瀧本理修, 菊地尚平, 宮西浩嗣, 佐藤康史, 加藤淳二
    • Organizer
      第14回日本がん分子標的治療学会学術集会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-21591213
  • [Presentation] Exosomes derived from AML/MDS cells could be involved in stromal dysfunction and bone marrow failure

    • Author(s)
      Jomen W, Horiguchi H, Kobune M, Kikuchi S, Murase K, Ibata S, Iyama S, Sato T, Kamihara Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J
    • Organizer
      2015 Highlights of ASH in Asia
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2015-02-28 – 2015-03-01
    • Data Source
      KAKENHI-PROJECT-24659466
  • [Presentation] Exosomes derived from AML/MDS cells could be involved in stromal dysfunction and bone marrow failure.

    • Author(s)
      Horiguchi H, Kobune M, Kikuchi S, Jomen W, Murase K, Ibata S, Iyama S, Sato T, Kamihara Y, Miyanishi K, Sato Y, Hayashi T, Takimoto R, Kato J.
    • Organizer
      56th ASH Annual Meeting and Exposition
    • Place of Presentation
      San Francisco, U.S.A
    • Year and Date
      2014-12-06 – 2014-12-11
    • Data Source
      KAKENHI-PROJECT-24659466
  • 1.  KATO Junji (20244345)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 2.  KOBUNE Masayoshi (90336389)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 9 results
  • 3.  IYAMA Satoshi (50398319)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 4.  Miyanishi Koji (60372819)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  Sato Tsutomu (40404602)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  和田 暁法 (60775922)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  神原 悠輔 (10624421)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 8.  TAKIMOTO Rishu (10336399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  Michihiro Ono (80634675)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  宇佐美 信 (10773377)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  田中 信悟 (60561024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  池田 博 (60570132)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 13.  後藤 亜香利 (60722387)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 14.  岸 裕幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 15.  高田 弘一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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