AKIYAMA MASATOSHI 秋山正年

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AKIYAMA Masatoshi 秋山正年

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Researcher Number	80526450
Other IDs
Affiliation (Current)	2025: 東北大学, 医学系研究科, 大学院非常勤講師
Affiliation (based on the past Project Information) *help	2020 – 2023: 東北大学, 医学系研究科, 大学院非常勤講師 2019 – 2020: 東北大学, 医学系研究科, 准教授 2012 – 2018: 東北大学, 大学病院, 講師 2015: 東北大学, 心臓血管外科, 講師 2014: 東北大学, 病院, 講師 2011 – 2012: 東北大学, 病院, 講師 2010: 東北大学, 病院, 助教
Review Section/Research Field	Principal Investigator Cardiovascular surgery / Basic Section 55030:Cardiovascular surgery-related / Thoracic surgery Except Principal Investigator Basic Section 55030:Cardiovascular surgery-related / Cardiovascular surgery / Biomedical engineering/Biomaterial science and engineering / Thoracic surgery
Keywords	Principal Investigator 脊髄虚血 / ナノバブル / 対麻痺 / ラット / 体外循環 / ヘパリン / 炎症反応 / 凝固異常 / 心臓外科手術 / 人工心肺 … More / 血小板 / トロンボモジュリン / 脳・神経 / 血管 / nanobubble / 虚血再灌流障害 / 髄液酸素化 / 脳脊髄液髄液酸素化 / 虚血性脊髄障害 / 脳脊髄液酸素化 / 胸腹部大動脈瘤 / 補助循環 / 循環器・高血圧 / 心臓外科 / 人工心筋 / 低侵襲手術 / 僧帽弁閉鎖不全 / 心不全 … More Except Principal Investigator 循環器・高血圧 / 補助人工心臓 / PAI-1阻害化合物 / PAI-1阻害薬 / 心臓血管外科 / 癒着 / 再生医療 / Muse細胞 / 植込型補助人工心臓 / 後天性フォンウィルブランド症候群 / 消化管出血 / 出血合併症 / 先天性心疾患 / 人工心筋 / 解離モデルマウス / 急性大動脈解離Stanford B型 / 大動脈解離 / Stanford B型大動脈解離 / 急性大動脈解離Stanford B / Stanford B / 急性大動脈解離 / 薬剤徐放性 / 縦隔内癒着防止 / PAI-1阻害 / トラネキサム酸 / 薬剤徐放 / 癒着実験 / 重症心不全 / せん断応力 / フォンウィルブランド因子 / 出血性合併症 / 心臓移植 / 植え込み型補助人工心臓 / 癒着予防 / 胸骨正中切開 / 心臓手術 / ウサギ / マクロファージ / 縦隔内癒着 / プラスミン / 再手術 / TM5441 / PAI-1 / 再生医学 / 細胞治療 / 心筋炎 / マイクロマシン / 形状記憶合金線維 / 循環シミュレータ / モデリング / 末梢循環 / 人工臓器学 / shear stress / multimer解析 / 機械的補助循環 / 後天性von Willebrand 症候群 / vWF large multimer index / ADAMTS13 / Shear stress / vWF large multimer Index / 後天性von Willebrand症候群 / von Willebrand factor / 先天性心臓血管外科学 / 機械弁 / 生体弁 / バルサルバ洞 / 右室流出路再建 / 心臓大血管外科学 / 人工心臓 / 心臓外科 / 右心不全モデル / 右心不全 / 徐放 / 免疫抑制 / 医学 / 肺静脈狭窄 / 徐放製剤 / ラパマイシン / 内膜肥厚 / 肺静脈狭窄症 / 総肺静脈還流異常症 Less

開心術後の縦隔内癒着予防のための生体吸収性薬剤徐放性代用自己心膜の開発
- Principal Investigator
  
  前田恵
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Tohoku University
The inhibitory effect of thrombomodulin on thrombocytopenia in a rat cardiopulmonary bypass modelPrincipal Investigator
- Principal Investigator
  
  Akiyama Masatoshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Tohoku University
Establishment of Preoperative Prediction System for Bleeding Complications in Patients with Implantable Left Ventricular Assist Devices
- Principal Investigator
  
  Saiki Yoshikatsu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Tohoku University
A novel adhesion prevention strategy using PAI-1 inhibitor
- Principal Investigator
  
  Kawatsu Satoshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Tohoku University
New therapeutic strategy in mouse acute aortic dissection induced by intravenously administrated human-Muse cells
- Principal Investigator
  
  Adachi Osamu
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55030:Cardiovascular surgery-related
- Research Institution
  Tohoku University
Novel cell therapy for myocarditis
- Principal Investigator
  
  Takahashi Goro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Tohoku University
New Treatment Concept with Nanobubble Technology for Spinal Cord Ischemic InjuryPrincipal Investigator
- Principal Investigator
  
  Akiyama Masatoshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Tohoku University
Elucidation of acquired von Willebrand syndrome in cases with mechanical circulation support
- Principal Investigator
  
  Fujiwara Hidenori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Tohoku University
Development of protection for spinal cord ischemic injury with oxygenation of the cerebrospinal fluid applying nanobubble generation technique.Principal Investigator
- Principal Investigator
  
  AKIYAMA MASATOSHI
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Tohoku University
Modelling of peripheral perfusion during mechanical circulatory system support
- Principal Investigator
  
  Shiraishi Yasuyuki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tohoku University
Impact of sinus Valsalva formation in valved conduits on prosthetic valve function placed in low pressure circulatory system; an ex-vivo comparative study
- Principal Investigator
  
  SAI Sadahiro
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cardiovascular surgery
- Research Institution
  Tohoku University
Mechanical circulatory support system development platform for congenital heart diseases using a small implantable actuator
- Principal Investigator
  
  Shiraishi Yasuyuki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  Tohoku University
Experimental study of preventive effect of drug-eluting film for pulmonary vein obstruction in the piglet model
- Principal Investigator
  
  ADACHI Osamu
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Tohoku University
Development of implantable artificial myocardial assist device for right ventricular support
- Principal Investigator
  
  MASUDA SHINYA
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Tohoku University
The possibility of artificial myocardial assist system to support failed heart model.Principal Investigator
- Principal Investigator
  
  AKIYAMA Masatoshi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Thoracic surgery
- Research Institution
  Tohoku University

All 2018 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] Association between severity of acquired von Willebrand syndrome and gastrointestinal bleeding after continuous flow left ventricular assist device implantation2018
- Author(s)
  Ko Sakatsume, Kenki Saito, Masatoshi Akiyama, Konosuke Sasaki, Satoshi Kawatsu, Goro Takahashi, Osamu Adachi, Shunsuke Kawamoto, Hisanori Horiuchi, Yoshikatsu Saiki
- Journal Title
  
  European Journal of Cardio-Thoracic Surgery
  
  Volume: -
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10204
[Journal Article] Intractable bleeding tendency due to acquired von Willebrand syndrome after Jarvik 2000 implant.2016
- Author(s)
  Sakatsume K, Akiyama M, Saito K, Kawamoto S, Horiuchi H, Saiki Y.
- Journal Title
  
  Journal of Artificial Organs
  
  Volume: - Issue: 3 Pages: 1-4
- DOI
  10.1007/s10047-016-0896-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10204
[Journal Article] Frameworks in attachment of an artificial myocardium on chronic heart models using shape memory alloy fibers2013
- Author(s)
  Shiraishi Y, Yambe T, Hayatsu Y, Akiyama M, Yamada A, Hashem M, Tsuboko Y, Miura H, Homma D
- Journal Title
  
  Int J Artif Organs
  
  Volume: 36(8) Pages: 575-575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282126
[Journal Article] Preliminary validation of a new magnetic wireless blood pump2013
- Author(s)
  Kim SH, Ishiyama K, Hashi S, Shiraishi Y, Hayatsu Y, Akiyama M, Saiki Y, Yambe T
- Journal Title
  
  Artif Organs
  
  Volume: 37(10) Issue: 10 Pages: 920-6
- DOI
  10.1111/aor.12093
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25282126
[Presentation] vWF large multimer index could be a predictive value of gastrointestinal bleedings after LVAD implantation2018
- Author(s)
  Ko Sakatsume, Masatoshi Akiyama, Yusuke Suzuki, Satoshi Kawatsu, Ichiro Yoshioka, Goro Takahashi, Kiichiro Kumagai, Osamu Adachi, Hisanori Horiuchi, Yoshikatsu Saiki
- Organizer
  第８２回日本循環器学会
- Data Source
  KAKENHI-PROJECT-15K10204
[Presentation] Bleeding complications after LVAD implantation -Quantitative method of acquired von Willebrand syndrome-2016
- Author(s)
  Ko Sakatsume, Masatoshi Akiyama,Kiichiro Kumagai, Shunsuke Kawamoto, Hisanori Horiuchi, Yoshikatsu Saiki
- Organizer
  第46回日本心臓血管外科学会
- Place of Presentation
  名古屋国際会議場（名古屋市）
- Year and Date
  2016-02-15
- Data Source
  KAKENHI-PROJECT-15K10204
[Presentation] 植込型補助人工心臓における出血合併症-後天性フォンウィルブランド症候群の定量的評価-2016
- Author(s)
  坂爪　公、秋山正年、斎藤健貴、川本俊輔、堀内久徳、齋木佳克
- Organizer
  第44回人工心臓と補助循環懇話会学術集会
- Place of Presentation
  ホテル松島大観荘（松島町）
- Year and Date
  2016-03-04
- Data Source
  KAKENHI-PROJECT-15K10204
[Presentation] Acquired von Willebrand Syndrome in Patients with Implantable Left Ventricular Assist Device2016
- Author(s)
  Ko Sakatsume, Masatoshi Akiyama, Kenki Saito, Ichiro Yoshioka, Shinya Masuda, Hidenori Fujiwara,Osamu Adachi, Kiichiro Kumagai, Shunsuke Kawamoto, Hisanori Horiuchi, Yoshikatsu Saiki
- Organizer
  第80回日本循環器学会総会
- Place of Presentation
  仙台国際センター（仙台市）
- Year and Date
  2016-03-18
- Data Source
  KAKENHI-PROJECT-15K10204
[Presentation] 埋込型小型右心人工心筋プロトタイプの開発設計2015
- Author(s)
  白石泰之、片平晋太郎、秋山正年、早津幸弘、齋木佳克、山家智之、本間大
- Organizer
  第43回人工心臓と補助循環懇話会学術集会
- Place of Presentation
  熱海
- Year and Date
  2015-02-21
- Data Source
  KAKENHI-PROJECT-25282126
[Presentation] 右心模擬循環シミュレーションモデルによる小型右心用人工心筋の改良2015
- Author(s)
  白石泰之、片平晋太郎、山田昭博、井上雄介、三浦英和、秋山正年、齋木佳克、山家智之、本間大
- Organizer
  第53回日本人工臓器学会大会
- Place of Presentation
  東京ドームシティ（東京）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-25282126
[Presentation] Non invasive evaluation of the renal blood flow during left ventricular assistance2015
- Author(s)
  Shiraishi Y, Yambe T, Inoue Y, Sasaki K, Miura H, Tanaka A, Yoshizawa M, Katahira S, Akiyama M, Saiki Y
- Organizer
  第54回日本生体医工学会大会
- Place of Presentation
  名古屋国際会議場（名古屋）
- Year and Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-25282126
[Presentation] Non invasive evaluation of the renal blood flow during left ventricular assistance2015
- Author(s)
  Shiraishi Y, Yambe T, Inoue Y, Sasaki K, Miura H, Tanaka A, Yoshizawa M, Katahira S, Akiyama M, Saiki Y
- Organizer
  IUPEM-World Congress 2015
- Place of Presentation
  トロント（カナダ）
- Year and Date
  2015-11-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26560199
[Presentation] 形状記憶合金線維を応用した完全埋め込み型右心補助人工心臓開発設計2014
- Author(s)
  白石泰之、片平晋太郎、金子芳一、山田昭博、秋山正年、齋木佳克、三浦英和、山家智之、本間大
- Organizer
  第52回日本人工臓器学会大会
- Place of Presentation
  札幌
- Year and Date
  2014-10-19
- Data Source
  KAKENHI-PROJECT-25282126
[Presentation] First Analysis Of Artificial Myocardium Applied To Chronic Heart Failure In Canine Model2013
- Author(s)
  Yukihiro Hayatsu, Masatoshi Akiyama, Yasuyuki Shiraishi, Akihiro Yamada, Kazumasu Sasaki, Shunsuke Kawamoto,Tomoyuki Yambe, Yoshikatsu Saiki
- Organizer
  ASAIO 59th Annual Conference(2013)
- Place of Presentation
  シカゴ、米国
- Data Source
  KAKENHI-PROJECT-22591534
[Presentation] 本間大極細形状記憶合金線維の多層化による人工心筋システムの改良2012
- Author(s)
  白石泰之,山田昭博,Mohamed Hashem Omran,坪子侑佑,三浦英和,西條芳文,山家智之,秋山正年,早津幸弘,齋木佳克
- Organizer
  2012年日本人工臓器学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22591534

1. SAIKI Yoshikatsu (50372298)

# of Collaborated Projects: 14 results

# of Collaborated Products: 12 results
2. YANBE Tomoyuki (70241578)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
3. ADACHI Osamu (30375092)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. KUMAGAI Kiichiro (80396564)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. KAWAMOTO Shunsuke (20400244)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. SHIRAISHI Yasuyuki (00329137)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
7. SHIBUYA Takumi (10526453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MOTOYOSHI Naotaka (40375093)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. Kawatsu Satoshi (80633685)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
10. MIURA HIDEKAZU (50451894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
11. SASAKI KAZUMASU (80738948)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
12. 坂爪公 (10837032)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. 鈴木智之 (10837157)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
14. 佐々木康之輔 (50755642)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
15. KAKISAKI Shuhei (10547417)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MASUDA SHINYA (30596094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. SAI Sadahiro (60312576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. Fujiwara Hidenori (20747117)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. YAMAGISHI MASAAKI (40182422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. Takahashi Goro (50526449)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 細山勝寛 (70837046)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 丸山修 (30358064)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 土方亘 (30618947)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 堀内久徳 (90291426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 吉岡一朗 (90770272)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 前田恵 (00646151)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

AKIYAMA MASATOSHI 秋山 正年

AKIYAMA Masatoshi 秋山 正年

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The inhibitory effect of thrombomodulin on thrombocytopenia in a rat cardiopulmonary bypass modelPrincipal Investigator

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New Treatment Concept with Nanobubble Technology for Spinal Cord Ischemic InjuryPrincipal Investigator

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Development of protection for spinal cord ischemic injury with oxygenation of the cerebrospinal fluid applying nanobubble generation technique.Principal Investigator

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The possibility of artificial myocardial assist system to support failed heart model.Principal Investigator

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AKIYAMA MASATOSHI 秋山正年

AKIYAMA Masatoshi 秋山正年