Haga Kei 芳賀慧

Researcher Number	80528373
Other IDs
Affiliation (Current)	2025: 北里大学, 大村智記念研究所, 講師 2025: 北里大学, 感染制御科学府, 講師
Affiliation (based on the past Project Information) *help	2024: 北里大学, 大村智記念研究所, 講師 2022 – 2023: 北里大学, 感染制御科学府, 講師 2021: 北里大学, 大村智記念研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 54030:Infectious disease medicine-related
Keywords	Principal Investigator 腸管オルガノイド / ノロウイルス / ウイルス性胃腸炎 / オルガノイド / ヒトノロウイルス

腸管オルガノイドを用いたヒトノロウイルス増殖機構の解明Principal Investigator
- Principal Investigator
  
  芳賀慧
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kitasato University
Identification of host factors of intestinal organoids involved in human norovirus susceptibilityPrincipal Investigator
- Principal Investigator
  
  Haga Kei
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54030:Infectious disease medicine-related
- Research Institution
  Kitasato University

All 2024 2023 2022 2021

All Journal Article Presentation

[Journal Article] Production of infectious reporter murine norovirus by VP2 trans-complementation2024
- Author(s)
  Ishiyama Ryoka、Yoshida Kazuhiro、Oikawa Kazuki、Takai-Todaka Reiko、Kato Akiko、Kanamori Kumiko、Nakanishi Akira、Haga Kei、Katayama Kazuhiko
- Journal Title
  
  Journal of Virology
  
  Volume: 98 Issue: 2
- DOI
  10.1128/jvi.01261-23
- Data Source
  KAKENHI-PROJECT-21K08496
[Journal Article] Experimental Adaptation of Murine Norovirus to Calcium Hydroxide2022
- Author(s)
  Oishi Wakana、Sato Mikiko、Kubota Kengo、Ishiyama Ryoka、Takai-Todaka Reiko、Haga Kei、Katayama Kazuhiko、Sano Daisuke
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 13 Pages: 848439-848439
- DOI
  10.3389/fmicb.2022.848439
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H03792, KAKENHI-PROJECT-20J10868, KAKENHI-PROJECT-21K08496
[Journal Article] Luciferase‐based quantification of membrane fusion induced by SARS‐CoV‐2 S protein2022
- Author(s)
  Haga Kei、Takai‐Todaka Reiko、Sawada Akihito、Katayama Kazuhiko
- Journal Title
  
  Genes to Cells
  
  Volume: 27 Issue: 8 Pages: 537-543
- DOI
  10.1111/gtc.12945
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08496
[Journal Article] Generation of CRISPR-Cas9-mediated genetic knockout human intestinal tissue?derived enteroid lines by lentivirus transduction and single-cell cloning2022
- Author(s)
  Lin Shih-Ching、Haga Kei、Zeng Xi-Lei、Estes Mary K.
- Journal Title
  
  Nature Protocols
  
  Volume: 17 Issue: 4 Pages: 1004-1027
- DOI
  10.1038/s41596-021-00669-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08496
[Journal Article] Genotype-dependent kinetics of enterovirus inactivation by free chlorine and ultraviolet (UV) irradiation2022
- Author(s)
  Torii Shotaro、Corre Marie-Helene、Miura Fuminari、Itamochi Masae、Haga Kei、Katayama Kazuhiko、Katayama Hiroyuki、Kohn Tamar
- Journal Title
  
  Water Research
  
  Volume: 220 Pages: 118712-118712
- DOI
  10.1016/j.watres.2022.118712
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20J10268, KAKENHI-PROJECT-21K08496, KAKENHI-PROJECT-22KJ2358, KAKENHI-PROJECT-20H00259
[Journal Article] 腸管由来オルガノイドを用いたヒトノロウイルス研究2022
- Author(s)
  芳賀慧　戸高玲子　片山和彦
- Journal Title
  
  臨床とウイルス
  
  Volume: 50 Pages: 60-64
- Data Source
  KAKENHI-PROJECT-21K08496
[Journal Article] Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening2021
- Author(s)
  Ebisudani Toshiki、Sugimoto Shinya、Haga Kei、Mitsuishi Akifumi、Takai-Todaka Reiko、Fujii Masayuki、Toshimitsu Kohta、Hamamoto Junko、Sugihara Kai、Hishida Tomoyuki、Asamura Hisao、Fukunaga Koichi、Yasuda Hiroyuki、Katayama Kazuhiko、Sato Toshiro
- Journal Title
  
  Cell Reports
  
  Volume: 35 Issue: 10 Pages: 109218-109218
- DOI
  10.1016/j.celrep.2021.109218
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08610, KAKENHI-PROJECT-20H03757, KAKENHI-PROJECT-21K08496, KAKENHI-PROJECT-20H03746
[Journal Article] Impact of the Heterogeneity in Free Chlorine, UV254, and Ozone Susceptibilities Among Coxsackievirus B5 on the Prediction of the Overall Inactivation Efficiency2021
- Author(s)
  Torii Shotaro、Miura Fuminari、Itamochi Masae、Haga Kei、Katayama Kazuhiko、Katayama Hiroyuki
- Journal Title
  
  Environmental Science & Technology
  
  Volume: 55 Issue: 5 Pages: 3156-3164
- DOI
  10.1021/acs.est.0c07796
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00259, KAKENHI-PROJECT-20J10268, KAKENHI-PROJECT-21K08496, KAKENHI-PROJECT-22KJ2358
[Journal Article] Nasal delivery of single-domain antibody improves symptoms of SARS-CoV-2 infection in an animal model2021
- Author(s)
  Haga Kei、Takai-Todaka Reiko、Matsumura Yuta、Song Chihong、Takano Tomomi、Tojo Takuto、Nagami Atsushi、Ishida Yuki、Masaki Hidekazu、Tsuchiya Masayuki、Ebisudani Toshiki、Sugimoto Shinya、Sato Toshiro、Yasuda Hiroyuki、Fukunaga Koichi、Sawada Akihito、Nemoto Naoto、Murata Kazuyoshi、Morimoto Takuya、Katayama Kazuhiko
- Journal Title
  
  PLOS Pathogens
  
  Volume: 17 Issue: 10 Pages: 1009542-1009542
- DOI
  10.1371/journal.ppat.1009542
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08496, KAKENHI-PROJECT-21K19540, KAKENHI-PROJECT-21H05025, KAKENHI-PROJECT-20H03746
[Presentation] Neonatal Fc receptor works as a classical human astrovirus receptor2024
- Author(s)
  Kei Haga
- Organizer
  The Joint 24th International Conference on Emerging Infectious Diseases in the Pacific Rim of the U.S.-Japan Cooperative Medical Sciences Program
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] Neonatal Fc receptor is a functional receptor for human astrovirus2023
- Author(s)
  Kei Haga, Reiko Takai-Todaka, Ryoka Ishiyama, Azusa Ishikawa, Kana Miyamaoto, Akiko Kato, Kazuhiko Katayama, Akira Nakanishi
- Organizer
  International Calicivirus meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] ヒトサポウイルス増殖培養系の検討2023
- Author(s)
  石川梓、戸高玲子、石山涼翔、芳賀慧、片山和彦
- Organizer
  第70回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] MNV複製増殖機構におけるMNVゲノム上のステムループ構造の機能解析2023
- Author(s)
  松永健太郎, 石山涼翔, 戸高玲子, 芳賀慧, 片山和彦
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] Production of murine norovirus-based reporter virus.2023
- Author(s)
  Ryoka Ishiyama, Oikawa Kazuki, Haga Kei, Reiko Takai-Todaka, Kazuhiko Katayama, Nakanishi Akira
- Organizer
  International Calicivirus meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] ノロウイルス感染患者の腸管粘膜免疫応答の研究2023
- Author(s)
  海田梓乃、三木元博、戸高玲子、石山涼翔、芳賀慧、片山和彦
- Organizer
  第70回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] ヒトアストロウイルス遺伝子型による抗原性とレセプター親和性の比較2023
- Author(s)
  宮本華奈, 石山涼翔, 戸高玲子, 芳賀慧, 片山和彦
- Organizer
  第46回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] Genome wide knockout by CRISPR-Cas9 revealed Human Astrovirus receptor2022
- Author(s)
  芳賀　慧
- Organizer
  第69回　日本ウイルス学会　学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-21K08496
[Presentation] The exploration of astrovirus receptor2021
- Author(s)
  工藤栞　芳賀慧　戸高玲子　中西章　片山和彦
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-21K08496

1. HAMAMOTO Junko

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 安田浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 片山浩之

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 鳥居将太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 三浦尚之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Haga Kei 芳賀 慧

Research Projects

Research Products

Co-Researchers

腸管オルガノイドを用いたヒトノロウイルス増殖機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of host factors of intestinal organoids involved in human norovirus susceptibilityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Production of infectious reporter murine norovirus by VP2 trans-complementation2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Experimental Adaptation of Murine Norovirus to Calcium Hydroxide2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Luciferase‐based quantification of membrane fusion induced by SARS‐CoV‐2 S protein2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of CRISPR-Cas9-mediated genetic knockout human intestinal tissue?derived enteroid lines by lentivirus transduction and single-cell cloning2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genotype-dependent kinetics of enterovirus inactivation by free chlorine and ultraviolet (UV) irradiation2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 腸管由来オルガノイドを用いたヒトノロウイルス研究2022

Author(s)

Journal Title

Data Source

[Journal Article] Direct derivation of human alveolospheres for SARS-CoV-2 infection modeling and drug screening2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of the Heterogeneity in Free Chlorine, UV254, and Ozone Susceptibilities Among Coxsackievirus B5 on the Prediction of the Overall Inactivation Efficiency2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nasal delivery of single-domain antibody improves symptoms of SARS-CoV-2 infection in an animal model2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] Neonatal Fc receptor works as a classical human astrovirus receptor2024

Author(s)

Organizer

Data Source

[Presentation] Neonatal Fc receptor is a functional receptor for human astrovirus2023

Author(s)

Organizer

Data Source

[Presentation] ヒトサポウイルス増殖培養系の検討2023

Author(s)

Organizer

Data Source

[Presentation] MNV複製増殖機構におけるMNVゲノム上のステムループ構造の機能解析2023

Author(s)

Organizer

Data Source

[Presentation] Production of murine norovirus-based reporter virus.2023

Author(s)

Organizer

Data Source

Haga Kei 芳賀慧