INOUE HIROYUKI 井上博之

… Alternative Names

井上博之イノウエヒロユキ

INOUE HIORYUKI 井上博之

INOUE Hiroyuki 井上博之

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Researcher Number	80529967
Other IDs
Affiliation (Current)	2025: 福岡大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2023: 福岡大学, 医学部, 准教授 2020 – 2021: 福岡大学, 医学部, 准教授 2019: 九州大学, 大学病院, 特任講師 2014: 九州大学, 生体防御医学研究所, 講師 2009 – 2013: Kyushu University, 生体防御医学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Experimental pathology / Tumor therapeutics
Keywords	Principal Investigator 肺癌 / 免疫チェックポイント阻害剤 / GM-CSF / 腫瘍免疫 / Lung cancer / Humoral immune analysis / Predictive biomarker / ICI / バイオマーカー / 薬物療法 … More / 免疫原性細胞死（ICD) / DAMPs / 免疫原性細胞死 / CRT / EGFR-TKI / ICD : 免疫原性細胞死 / Calreticulin / NSCLC / DAMP / ICD / RNA干渉 / ﾊｲｽﾙｰﾌﾟｯﾄｽｸﾘｰﾆﾝｸﾞ / 腫瘍溶解性ウイルス / ゲノムワイドRNA干渉法 / エンテロウイルス / 腫瘍溶解性ウイルス療法 / ワクチン / 遺伝子治療 / 腫瘍免疫療法 / iPS細胞 / 癌幹細胞 / GVAX / LTB4 / BLT1 / メモリーT細胞 Less

Exploratory study of novel predictors of therapeutic efficacy of immune checkpoint inhibitors based on humoral immunological analysisPrincipal Investigator
- Principal Investigator
  
  井上博之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fukuoka University
Exploratory research for immunogenic cell death induced by anti-cancer drugs in lung cancerPrincipal Investigator
- Principal Investigator
  
  INOUE HIORYUKI
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fukuoka University
  Kyushu University
ゲノムワイドRNA干渉スクリーニング法による腫瘍溶解RNAウイルス増殖機構の解明Principal Investigator
- Principal Investigator
  
  井上博之
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Tumor therapeutics
- Research Institution
  Kyushu University
Development of novel cancer cell vaccine using GM-CSF gene-transuduced IPS cells targeting cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  INOUE Hiroyuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University
To clarify mechanism by which long-term antitumor immunity induced by GM-CSF gene transduced tumor cells is generated in the absence of LTB4/BLT1 signaling.Principal Investigator
- Principal Investigator
  
  INOUE Hiroyuki
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Experimental pathology
- Research Institution
  Kyushu University

All 2021 2020 2014 2013 2012 2011 2010 2008 Other

All Journal Article Presentation Book Patent

[Book] サイトカインと癌治療、臨床検査2010
- Author(s)
  井上博之, 谷憲三朗
- Total Pages
  6
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-21790387
[Book] サイトカインと癌治療臨床検査第54巻6号2010
- Author(s)
  井上博之、谷憲三朗
- Publisher
  医学書院(発行)
- Data Source
  KAKENHI-PROJECT-21790387
[Journal Article] Cytotoxic chemotherapeutic agents and the EGFR-TKI osimertinib induce calreticulin exposure in non-small cell lung cancer2021
- Author(s)
  Rie Furukawa, Hiroyuki Inoue, Yasuto Yoneshima, Hirono Tsutsumi, Eiji Iwama, Yuki Ikematsu, Nobuhisa Ando, Yoshimasa Shiraishi, Keiichi Ota, Kentaro Tanaka, Yoichi Nakanishi and Isamu Okamoto
- Journal Title
  
  Lung Cancer
  
  Volume: 155 Pages: 144-150
- DOI
  10.1016/j.lungcan.2021.03.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07733
[Journal Article] Coxsackievirus B3 Is an Oncolytic Virus with Immunostimulatory Properties that Is Active Against Lung Adenocarcinoma2012
- Author(s)
  Miyamoto S, Inoue H, Nakamura T, Yamada M, Sakamoto C, Urata Y, Okazaki T, Marumoto T, Takahashi A, Takayama K, Nakanishi Y, Shimizu H, Tani K
- Journal Title
  
  Cancer Research
  
  Volume: (掲載確定)(印刷中) Issue: 10 Pages: 2609-2621
- DOI
  10.1158/0008-5472.can-11-3185
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22659227, KAKENHI-PROJECT-23590465, KAKENHI-PROJECT-23659331, KAKENHI-PROJECT-23790446, KAKENHI-PROJECT-24300340, KAKENHI-PROJECT-24650629
[Patent] 新規腫瘍溶解性ウイルス2014
- Inventor(s)
  井上　博之
- Industrial Property Rights Holder
  井上　博之
- Industrial Property Rights Type
  特許
- Filing Date
  2014
- Overseas
- Data Source
  KAKENHI-PROJECT-25430151
[Presentation] Cytotoxic chemotherapeutic agents and the EGFR-TKI osimertinib induce calreticulin exposure in non small cell lung cancer2021
- Author(s)
  古川里恵、井上博之、池松祐樹、安藤伸尚、田中謙太郎、岡本勇
- Organizer
  第80回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19K07733
[Presentation] Pemetrexed induces calreticulin expression most robustly in parallel with apoptosis among chemotherapeutic agents used in non-small cell lung cancer (NSCLC) treatment2020
- Author(s)
  Rie Furukawa, Hiroyuki Inoue, Hirono Tsutsumi, Nobuhisa Ando, Yuki Ikematsu, Eiji Iwama, Yasuto Yoneshima, Kentaro Tanaka, Yoichi Nakanishi, Isamu Okamoto
- Organizer
  The 111th Annual Meeting of the American Association of Cancer Research (AACR) (Virtual Annual Meeting II)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07733
[Presentation] A novel cancer cell vaccine using induced pluripotent stem cells genetically engineered to produce GM-CSF elicits substantial antitumor immunity in a syngeneic mouse model2013
- Author(s)
  Hiroyuki Inoue, Ayumi Watanabe,Chika Sakamoto, Megumi Narusawa, Shohei Miyamoto, Makoto Inoue, Koichi Takayama, Mamoru Hasegawa, Yo ichi Nakanishi, and Kenzaburo Tani.
- Organizer
  第16回米国遺伝子治療学会総会
- Place of Presentation
  ソルトレークシティ、米国
- Data Source
  KAKENHI-PROJECT-23790446
[Presentation] A novel cancer cell vaccine using induced pluripotent stem cells genetically engineered to produce GM-CSF elicits substantial antitumor immunity in a syngeneic mouse model2013
- Author(s)
  井上博之　（口頭発表）
- Organizer
  第16回米国遺伝子治療学会
- Place of Presentation
  ソルトレークシティ
- Data Source
  KAKENHI-PROJECT-23790446
[Presentation] Genetically engineered oncolytic Edmonston strain of measles virus harboring the wild-type N, P, L Genes (MV-NPL) effectively target lung cancer stem cells.2012
- Author(s)
  井上博之
- Organizer
  American Association of Cancer Research
- Place of Presentation
  米国　シカゴ
- Data Source
  KAKENHI-PROJECT-23790446
[Presentation] Novel cancer immunotherapy using induced pluripotent stem cells genetically engineered to produce GM-CSF2012
- Author(s)
  Ayumi Wanatabe, Hiroyuki Inoue, Chika Sakamoto, Megumi Narusawa, Shohei Miyamoto, Makoto Inoue, Keisuke Okita, Koichi Takayama, Mamoru Hasegawa, Yoichi Nakanishi, Shinya Yamanaka, and Kenzaburo Tani
- Organizer
  第71回日本癌学会学術総会
- Place of Presentation
  ロイトン札幌
- Data Source
  KAKENHI-PROJECT-23790446
[Presentation] Large-Scale Screening Identifies Coxsackievirus B3 (CVB3) as a Promising Oncolytic Virotherapy Agent against Non-Small Cell Lung Cancer2011
- Author(s)
  井上博之
- Organizer
  European Society of Gene and Cell Therapy
- Place of Presentation
  英国　ブライトン
- Data Source
  KAKENHI-PROJECT-23790446
[Presentation] Loss of LTB4 Signaling Confers the Long-Term Antileukemia Effects Induced by GM-CSF -Transduced Tumor in BLT1 deficient Mice2008
- Author(s)
  Hiroyuki Inoue, Yosuke Yokota, Haruka Nabeta, Mutsunori Iga, Chika Sakamoto, Fumiyuki Sasaki, Yoichi Nakanishi, Takehiko Yokomizo, Kenzaburo Tani.
- Organizer
  第50回米国血液学会
- Place of Presentation
  サンフラシンスコ
- Data Source
  KAKENHI-PROJECT-21790387
[Presentation] Blocking LTB4 Signaling Confers the Long-Term Antitumor Effects Induced by GM-CSF-Transduced Tumor in BLT1 Deficient Mice2008
- Author(s)
  Hiroyuki Inoue, Yosuke Yokota, Haruka Nabeta, Mutsunori Iga, Chika Sakamoto^1, Fumiyuki Sasaki, Yoichi Nakanishi, Takehiko Yokomizo, Kenzaburo Tani.
- Organizer
  第2回グローバルCOE国際シンポジウム/第18回九州大学生体防御医学研究所ホットスプリングハーバーシンポジウム
- Place of Presentation
  福岡市
- Data Source
  KAKENHI-PROJECT-21790387
[Presentation] Blocking of the LTB4 Signaling Maintains the in vivo Antitumor Effects of GM-CSF in the tumor challenged BLT1-/- mice2008
- Author(s)
  Haruka Nabeta, Hiroyuki Inoue, Mutsunori Iga, Yosuke Yokota, Ryo Kurita, Fumiyuki Sasaki, Koichi Takayama, Yoichi Nakanishi, Takehiko Yokomizo, Kenzaburo Tani.
- Organizer
  第70回日本血液学会総会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-21790387
[Presentation] Coxsackievirus A11 displays remarkable oncolytic activity against human non-small cell lung cancer cells.
- Author(s)
  HIROYUKI INOUE
- Organizer
  第20回日本遺伝子治療学会
- Place of Presentation
  慈恵医科大学（東京）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25430151
[Presentation] Coxsackievirus A11 possesses extensive oncolytic activity against human non-small cell lung cancer cells.
- Author(s)
  HIROYUKI　INOUE
- Organizer
  第17回米国遺伝子治療学会
- Place of Presentation
  New Orleans （アメリカ合衆国）
- Year and Date
  2014-05-21 – 2014-05-24
- Data Source
  KAKENHI-PROJECT-25430151
[Presentation] Coxsackievirus A11 exhibits ICAM-1-mediated oncolysis against human non-small cell lung cancer cells.
- Author(s)
  HIROYUKI INOUE
- Organizer
  第73回日本癌学会総会
- Place of Presentation
  パシフィコ横浜（横浜）
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25430151

1. 中村貴史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INOUE HIROYUKI 井上 博之

井上 博之 イノウエ ヒロユキ

INOUE HIORYUKI 井上 博之

INOUE Hiroyuki 井上 博之

Research Projects

Research Products

Co-Researchers

Exploratory study of novel predictors of therapeutic efficacy of immune checkpoint inhibitors based on humoral immunological analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploratory research for immunogenic cell death induced by anti-cancer drugs in lung cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

ゲノムワイドRNA干渉スクリーニング法による腫瘍溶解RNAウイルス増殖機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of novel cancer cell vaccine using GM-CSF gene-transuduced IPS cells targeting cancer stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

To clarify mechanism by which long-term antitumor immunity induced by GM-CSF gene transduced tumor cells is generated in the absence of LTB4/BLT1 signaling.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] サイトカインと癌治療、臨床検査2010

Author(s)

Total Pages

Publisher

Data Source

[Book] サイトカインと癌治療臨床検査 第54巻6号2010

Author(s)

Publisher

Data Source

[Journal Article] Cytotoxic chemotherapeutic agents and the EGFR-TKI osimertinib induce calreticulin exposure in non-small cell lung cancer2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Coxsackievirus B3 Is an Oncolytic Virus with Immunostimulatory Properties that Is Active Against Lung Adenocarcinoma2012

Author(s)

Journal Title

DOI

Data Source

[Patent] 新規腫瘍溶解性ウイルス2014

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Cytotoxic chemotherapeutic agents and the EGFR-TKI osimertinib induce calreticulin exposure in non small cell lung cancer2021

Author(s)

Organizer

Data Source

[Presentation] Pemetrexed induces calreticulin expression most robustly in parallel with apoptosis among chemotherapeutic agents used in non-small cell lung cancer (NSCLC) treatment2020

Author(s)

Organizer

Data Source

[Presentation] A novel cancer cell vaccine using induced pluripotent stem cells genetically engineered to produce GM-CSF elicits substantial antitumor immunity in a syngeneic mouse model2013

Author(s)

Organizer

Place of Presentation

Data Source

[Presentation] A novel cancer cell vaccine using induced pluripotent stem cells genetically engineered to produce GM-CSF elicits substantial antitumor immunity in a syngeneic mouse model2013

Author(s)

Organizer

Place of Presentation

Data Source

INOUE HIROYUKI 井上博之

井上博之イノウエヒロユキ

INOUE HIORYUKI 井上博之

INOUE Hiroyuki 井上博之

[Book] サイトカインと癌治療臨床検査第54巻6号2010