HOSONO KANAKO 細野加奈子

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HOSONO Kanako 細野加奈子

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Researcher Number	80532556
Affiliation (Current)	2025: 北里大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 北里大学, 医学部, 講師 2020 – 2023: 北里大学, 医学部, 講師 2018 – 2019: 北里大学, 医学部, 助教 2017: 北里大学, 医学部, 非常勤講師 2011 – 2016: 北里大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / General pharmacology Except Principal Investigator Basic Section 48030:Pharmacology-related / Biological Sciences
Keywords	Principal Investigator ノックアウトマウス / 慢性炎症 / リンパ管新生 / 肥満 / RAMP1 / CGRP / 脂肪吸収 / リンパ節転移 / がん / プロスタグランジン / 脂肪肝炎 / 腸管リンパ管 / TP受容体 … More Except Principal Investigator … More TP受容体 / トロンボキサン / 炎症 / 受容体 / VEGF-C / COX-2 / リンパ節転移 / 浮腫 / リンパ管新生 / プロスタグランジン / 緑内障 / がん転移 / プロスタグランジンン / mPHES-1 / LPS / 脂質吸収 / リンパ浮腫 / DSS腸炎 / 腹膜炎 / 子宮内膜症 / 大腸炎 / 肝障害 / 生理活性ペプチド / リンパ流 / 生理活性脂質 / 生理活性資質 / IP受容体 / 虚血モデル / 微小循環 / セレクチン / 血小板 / 血管新生 / 腫瘍 / Cyclooxygenase / Prostaglandin / dendritic cell / SDF1 / VEGF / EP3シグナリング / TPシグナリング / regulatory T cell / SDF-1 / EP3 / premetastatic niche / がん / 樹状細胞 / 前転移ニッテェ / 慢性炎症 / がんリンパ節転移 / サイクロオキシゲナーゼ Less

肥満炎症性腸疾患の粘膜修復を制御する知覚神経―免疫細胞相互作用Principal Investigator
- Principal Investigator
  
  細野加奈子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kitasato University
脂肪肝炎と腸管脂肪吸収とを制御する神経―免疫クロストークの役割解明Principal Investigator
- Principal Investigator
  
  細野加奈子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kitasato University
The role of calcitonin gene-related peptide (CGRP) in regulation of intestinal fat absorptionPrincipal Investigator
- Principal Investigator
  
  Hosono Kanako
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Kitasato University
Bioactive lipids as regulators of plasticity of lymphatics
- Principal Investigator
  
  Majima Masataka
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Kitasato University
Role of TP signaling in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis modelPrincipal Investigator
- Principal Investigator
  
  Hosono Kanako
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Kitasato University
Roles of prostanoid during premetastatic niche formation in regional lymph nodePrincipal Investigator
- Principal Investigator
  
  HOSONO Kanako
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kitasato University
Roles of prostanoids in facilitation of lymphangiogenesis and lymph node metastasis
- Principal Investigator
  
  MAJIMA Masataka
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kitasato University
Role of prostaglandin receptor signaling inenhancement of lymphangiogenesis and application to metastasis treatmentPrincipal Investigator
- Principal Investigator
  
  HOSONO Kanako
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Kitasato University

All 2023 2022 2021 2020 2019 2017 2016 2015 2014 2013 2012 2011 Other

All Journal Article Presentation Book

[Book] 実験医学2017
- Author(s)
  馬嶋正隆、天野英樹、細野加奈子
- Total Pages
  7
- Publisher
  洋土社
- Data Source
  KAKENHI-PROJECT-15K08241
[Book] 炎症と免疫2016
- Author(s)
  馬嶋正隆、天野英樹、細野加奈子
- Total Pages
  10
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-15K08241
[Journal Article] Deletion of RAMP1 Signaling Enhances Diet-induced Obesity and Fat Absorption via Intestinal Lacteals in Mice2023
- Author(s)
  HOSONO KANAKO、YAMASHITA ATSUSHI、TANABE MINA、ITO YOSHIYA、MAJIMA MASATAKA、TSUJIKAWA KAZUTAKE、AMANO HIDEKI
- Journal Title
  
  In Vivo
  
  Volume: 38 Issue: 1 Pages: 160-173
- DOI
  10.21873/invivo.13422
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06651, KAKENHI-PROJECT-22K06870
[Journal Article] Biologically active lipids in the regulation of lymphangiogenesis in disease states2022
- Author(s)
  Majima Masataka、Hosono Kanako、Ito Yoshiya、Amano Hideki
- Journal Title
  
  Pharmacology & Therapeutics
  
  Volume: 232 Pages: 108011-108011
- DOI
  10.1016/j.pharmthera.2021.108011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07127, KAKENHI-PROJECT-22K06870, KAKENHI-PROJECT-22K08942, KAKENHI-PROJECT-22K09010, KAKENHI-PROJECT-19K09291, KAKENHI-PROJECT-19K09250
[Journal Article] Roles of Thromboxane Receptor Signaling in Enhancement of Lipopolysaccharide-Induced Lymphangiogenesis and Lymphatic Drainage Function in Diaphragm.2021
- Author(s)
  Matsuda H, Ito Y, Hosono K, Tsuru S, Inoue T, Nakamoto S, Kurashige C, Hirashima M, Narumiya S, Okamoto H, Majima M.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 41 Issue: 4 Pages: 1390-1407
- DOI
  10.1161/atvbaha.120.315507
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02605, KAKENHI-PROJECT-19K07127, KAKENHI-PROJECT-19K09156, KAKENHI-PROJECT-19K16297
[Journal Article] Prostaglandin E receptor EP4 stimulates lymphangiogenesis to promote mucosal healing during DSS-induced colitis2020
- Author(s)
  Hosono Kanako、Kojo Ken、Narumiya Shuh、Majima Masataka、Ito Yoshiya
- Journal Title
  
  Biomedicine & Pharmacotherapy
  
  Volume: 128 Pages: 110264-110264
- DOI
  10.1016/j.biopha.2020.110264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07127, KAKENHI-PROJECT-20K17702, KAKENHI-PROJECT-18H02605
[Journal Article] Inhibition of receptor activity?modifying protein 1 suppresses the development of endometriosis and the formation of blood and lymphatic vessels2020
- Author(s)
  Honda Masako、Ito Yoshiya、Hattori Kyoko、Hosono Kanako、Sekiguchi Kazuki、Tsujikawa Kazutake、Unno Nobuya、Majima Masataka
- Journal Title
  
  Journal of Cellular and Molecular Medicine
  
  Volume: 24 Issue: 20 Pages: 11984-11997
- DOI
  10.1111/jcmm.15823
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07127, KAKENHI-PROJECT-18H02605, KAKENHI-PROJECT-19K18704
[Journal Article] Lymphangiogenesis induced by vascular endothelial growth factor receptor 1 signaling contributes to the progression of endometriosis in mice2020
- Author(s)
  Hattori Kyoko、Ito Yoshiya、Honda Masako、Sekiguchi Kazuki、Hosono Kanako、Shibuya Masabumi、Unno Nobuya、Majima Masataka
- Journal Title
  
  Journal of Pharmacological Sciences
  
  Volume: 143 Issue: 4 Pages: 255-263
- DOI
  10.1016/j.jphs.2020.05.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07127, KAKENHI-PROJECT-18H02605, KAKENHI-PROJECT-19K18704
[Journal Article] RAMP1 signaling in immune cells regulates inflammation-associated lymphangiogenesis2020
- Author(s)
  Tsuru Seri、Ito Yoshiya、Matsuda Hiromi、Hosono Kanako、Inoue Tomoyoshi、Nakamoto Shuji、Kurashige Chie、Mishima Toshiaki、Tsujikawa Kazutake、Okamoto Hirotsugu、Majima Masataka
- Journal Title
  
  Laboratory Investigation
  
  Volume: - Issue: 5 Pages: 738-750
- DOI
  10.1038/s41374-019-0364-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07127, KAKENHI-PROJECT-19K09156, KAKENHI-PROJECT-18K16994, KAKENHI-PROJECT-19K16297, KAKENHI-PROJECT-18H02605
[Journal Article] Role of the high-affinity leukotriene B4 receptor signaling in fibrosis after unilateral ureteral obstruction in mice2019
- Author(s)
  Kamata Mariko、Amano Hideki、Ito Yoshiya、Fujita Tomoe、Otaka Fumisato、Hosono Kanako、Kamata Kouju、Takeuchi Yasuo、Yokomizo Takehiko、Shimizu Takao、Majima Masataka
- Journal Title
  
  PLOS ONE
  
  Volume: 14 Issue: 2 Pages: 202842-202842
- DOI
  10.1371/journal.pone.0202842
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02605, KAKENHI-PROJECT-19K09250, KAKENHI-PROJECT-19KK0199, KAKENHI-ORGANIZER-15H05897, KAKENHI-PLANNED-15H05904, KAKENHI-PROJECT-18H02627
[Journal Article] CGRP/CGRP Receptor Antibodies: Potential Adverse Effects Due to Blockade of Neovascularization?2019
- Author(s)
  Majima Masataka、Ito Yoshiya、Hosono Kanako、Amano Hideki
- Journal Title
  
  Trends in Pharmacological Sciences
  
  Volume: 40 Issue: 1 Pages: 11-21
- DOI
  10.1016/j.tips.2018.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02605
[Journal Article] VEGF Receptor 1-Expressing Macrophages Recruited from Bone Marrow Enhances Angiogenesis in Endometrial Tissues.2019
- Author(s)
  Sekiguchi K, Ito Y, Hattori K, Inoue T, Hosono K, Honda M, Numao A, Amano H, Shibuya M, Unno N, Majima M
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 7037-7037
- DOI
  10.1038/s41598-019-43185-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09250, KAKENHI-PROJECT-19K18704, KAKENHI-PROJECT-18H02605
[Journal Article] 特集血管制御系と疾患生理活性脂質と脈管新生2017
- Author(s)
  馬嶋正隆、天野英樹、細野加奈子、伊藤義也
- Journal Title
  
  生体の科学
  
  Volume: 68 Issue: 4 Pages: 304-308
- DOI
  10.11477/mf.2425200634
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2017-08-15
- Open Access
- Data Source
  KAKENHI-PROJECT-15K08241
[Journal Article] Vascular endothelial growth factor receptor type 1 signaling prevents delayed wound healing in diabetes by attenuating the production of IL-1β by recruited macrophages.2016
- Author(s)
  Okizaki S, Ito Y, Hosono K, Oba K, Ohkubo H, Kojo K, Nishizawa N, Shibuya M, Majima M.
- Journal Title
  
  Am J Pathol
  
  Volume: 186(6) Pages: 1481-1498
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08241
[Journal Article] Prostaglandin E Receptors, EP3 and EP4 Facilitates Wound Healing and Lymphangiogenesis with Enhanced Recruitment of M2 Macrophages in Mice.2016
- Author(s)
  Hosono K, Isonaka R, Kawakami T, Narumiya S, Majima M.
- Journal Title
  
  PLoS One.
  
  Volume: 11 Issue: 10 Pages: e0162532-e0162532
- DOI
  10.1371/journal.pone.0162532
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293055, KAKENHI-PROJECT-15K15056, KAKENHI-PROJECT-15K08241
[Journal Article] プロスタグランジンによるリンパ管新生とリンパ組織可塑性の制御2015
- Author(s)
  馬嶋正隆、細野加奈子
- Journal Title
  
  医学のあゆみ
  
  Volume: 254 Pages: 1109-1114
- Data Source
  KAKENHI-PROJECT-15K08241
[Journal Article] Thromboxane A2 induces blood flow recovery via platelet adhesion to ischaemic regions.2015
- Author(s)
  Amano H, Ito Y, Eshima K, Kato S, Ogawa F, Hosono K, Oba K, Tamaki H, Sakagami H, Shibuya M, Narumiya S, Majima M.
- Journal Title
  
  Cardiovasc Res.
  
  Volume: 107 Issue: 4 Pages: 509-521
- DOI
  10.1093/cvr/cvv139
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K08241, KAKENHI-PROJECT-26430120, KAKENHI-PROJECT-26462132, KAKENHI-PROJECT-15H04672
[Journal Article] Role of cyclooxygenase-2 in the development of interstitial fibrosis in kidneys following unilateral ureteral obstruction in mice2015
- Author(s)
  Kamata M, Hosono K, Fujita T, Kamata K, Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 70 Pages: 174-180
- DOI
  10.1016/j.biopha.2015.01.010
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-26293055
[Journal Article] Roles of mPGES-1, an inducible prostaglandin E synthase, in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis model.2015
- Author(s)
  Matsuda H, Hosono K, Tsuru S, Kurashige C, Sekiguchi K, Akira S, Uematsu S, Okamoto H, Majima M.
- Journal Title
  
  Life Sci.
  
  Volume: 142 Pages: 1-7
- DOI
  10.1016/j.lfs.2015.10.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08241, KAKENHI-PROJECT-15K14404, KAKENHI-PROJECT-15K15056, KAKENHI-PUBLICLY-15H01367, KAKENHI-PROJECT-26293055
[Journal Article] Suppressed recruitment of alternatively activated macrophages reduces TGF-β1 and impairs wound healing in streptozotocin-induced diabetic mice.2015
- Author(s)
  Okizaki S, Ito Y, Hosono K, Oba K, Ohkubo H, Amano H, Shichiri M, Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 70 Pages: 317-325
- DOI
  10.1016/j.biopha.2014.10.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-26293055
[Journal Article] 病態時のリンパ管新生、リンパ組織の可塑性を制御するプロスタノイドの役割2015
- Author(s)
  馬嶋正隆、天野英樹、細野加奈子
- Journal Title
  
  細胞
  
  Volume: 47 Pages: 20-23
- Data Source
  KAKENHI-PROJECT-15K08241
[Journal Article] Aspirin reduces lung cancer metastasis to regional lymph nodes.2014
- Author(s)
  Ogawa F., Amano H., Ito H., Matsui Y., Hosono K., Kitasato H., Satoh Y., Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 68 Issue: 1 Pages: 79-86
- DOI
  10.1016/j.biopha.2013.11.006
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-23592073, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-25860192
[Journal Article] Downregulation of the proangiogenic prostaglandin E receptor EP3 and reduced angiogenesis in a mouse model of diabetes mellitus.2014
- Author(s)
  Oba K, Hosono K, Amano H, Okizaki S, Ito Y, Shichiri M, Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 68 Issue: 8 Pages: 1125-1133
- DOI
  10.1016/j.biopha.2014.10.022
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-26293055
[Journal Article] Prostanoid induces premetastatic niche in regional lymph nodes.2014
- Author(s)
  Ogawa F, Amano H, Eshima Y, Ito Y, Matsui Y, Hosono K, Kitasato H, Iyoda A, Iwabuchi K, Kumagai Y, Satoh Y, Narumiiya S, Majima M.
- Journal Title
  
  J. Clin. Invest.
  
  Volume: 124 Issue: 11 Pages: 4882-4894
- DOI
  10.1172/jci73530
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-25460502, KAKENHI-PROJECT-25860192, KAKENHI-PROJECT-26293055, KAKENHI-PROJECT-26462132
[Journal Article] Roles of microsomal prostaglandin E synthase-1 in lung metastasis formation in prostate cancer RM9 cells.2014
- Author(s)
  Takahashi R., Amano H., Satoh T., Tabata K., Ikeda M., Kitasato H., Akira S., Iwamura M., Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 28 Issue: 3 Pages: 1237-1247
- DOI
  10.1096/fj.13-238998
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-25860192
[Journal Article] NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4+ VEGFR1+ cells to theulcer granulation tissues.2013
- Author(s)
  Sato T, Amano H, Ito Y, Eshima K, Minamino T, Ae T, Katada C, Ohno T, Hosono K, Suzuki T, Shibuya M, Koizumi W, Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Journal Article] リンパ管新生：病態時の制御機構2013
- Author(s)
  細野加奈子、馬嶋正隆
- Journal Title
  
  日本薬理学会雑誌
  
  Volume: 141 Pages: 290-291
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116102
[Journal Article] NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4+ VEGFR1+ cells to theulcer granulation tissues.2013
- Author(s)
  Sato T., Amano H., Ito Y., Eshima K., Minamino .T, Ae T., Katada C., Ohno T., Hosono K., Suzuki T., Shibuya M., Koizumi W., Majima M.
- Journal Title
  
  Biomed Pharmacother
  
  Volume: 67 Issue: 7 Pages: 607-613
- DOI
  10.1016/j.biopha.2013.01.009
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102
[Journal Article] Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment.2013
- Author(s)
  Ohkubo H., Ito Y., Minamino T., Mishima T., Hirata M., Hosono K., Shibuya M., Yokomizo T., Shimizu T., Watanabe M., Majima M.
- Journal Title
  
  FASEB J.
  
  Volume: 27 Issue: 8 Pages: 3132-3143
- DOI
  10.1096/fj.13-227421
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-22116002, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-25462100, KAKENHI-PROJECT-25860192
[Journal Article] NSAID, aspirin delays gastric ulcer healing with reduced accumulation of CXCR4+ VEGFR1+ cells to the ulcer granulation tissues2013
- Author(s)
  Sato T, Amano H, Ito Y, Eshima K, Minamino T, Ae T, Katada C, Ohno T, Hosono K, Suzuki T, Shibuya M, Koizumi W, Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 183
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116102
[Journal Article] Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment.2013
- Author(s)
  Ohkubo H, Ito Y, Minamino T, Mishima T, Hirata M, Hosono K, Shibuya M, Yokomizo T, Shimizu T, Watanabe M, Majima M.
- Journal Title
  
  FASEB J.
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Journal Article] Lymphangiogenesis2013
- Author(s)
  細野加奈子、馬嶋正隆
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 141 Issue: 5 Pages: 290-291
- DOI
  10.1254/fpj.141.290
- NAID
  10031171132
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-25860192
[Journal Article] Vascular endothelial growth factor receptor 1 signaling facilitates gastric ulcer healing and angiogenesis through the up regulation of epidermal growth factor expression on VEGFR1+ CXCR4+ cells recruited from bone marrow.2013
- Author(s)
  Sato T., Amano H., Ito Y., Eshima K., Minamino T., Ae T., Katada C., Ohno T., Hosono K., Suzuki T., Shibuya M., Koizumi W., Majima M.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 49 Issue: 3 Pages: 455-469
- DOI
  10.1007/s00535-013-0869-z
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22116001, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-23592073, KAKENHI-PROJECT-24659119, KAKENHI-PROJECT-25860192
[Journal Article] Leukotriene B4 type-1 receptor signaling promotes liver repair after hepatic ischemia/reperfusion injury through the enhancement of macrophage recruitment2013
- Author(s)
  Ohkubo H, Ito Y, Minamino T, Mishima T, Hirata M, Hosono K, Shibuya M, Yokomizo T, Shimizu T, Watanabe M, Majima M.
- Journal Title
  
  FASEB Journal
  
  Volume: 68
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-23116102
[Journal Article] Thromboxane A(2) receptor signaling promotes liver tissue repair after toxic injury through the enhancement of macrophage recruitment.2012
- Author(s)
  Minamino T, Ito Y, Ohkubo H, Hosono K, Suzuki T, Sato T, Ae T, Shibuya A, Sakagami H, Narumiya S, Koizumi W, Majima M.
- Journal Title
  
  Toxicol Appl Pharmacol.
  
  Volume: 259(1) Pages: 104-114
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Journal Article] Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation.2011
- Author(s)
  Hosono K, Suzuki T, Tamaki H, Sakagami H, Hayashi I, Narumiya S, Alitalo K, Majima M.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 31(5) Pages: 1049-1058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Journal Article] Calcitonin gene-related peptide facilitates revascularization during hindlimb ischemia in mice.2011
- Author(s)
  Mishima T, Ito Y, Hosono K, Tamura Y, Uchida Y, Hirata M, Suzsuki T, Amano H, Kato S, Kurihara Y, Kurihara H, Hayashi I, Watanabe M, Majima M.
- Journal Title
  
  Am J Physiol Heart Circ Physiol.
  
  Volume: 300(2)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Journal Article] The inducible prostaglandin E synthase mPGES-1 regulates growth of endometrial tissues and angiogenesis in a mouse implantation model.2011
- Author(s)
  Numao A, Hosono K, Suzuki T, Hayashi I, Uematsu S, Akira S, Ogino Y, Kawauchi H, Unno N, Majima M.
- Journal Title
  
  Biomed Pharmacother.
  
  Volume: 65(1) Pages: 77-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Journal Article] Vascular endothelial growth factor receptor-1 signaling promotes liver repair through restoration of liver microvasculature after acetaminophen hepatotoxicity.2011
- Author(s)
  Kato T, Ito Y, Hosono K, Suzuki T, Tamaki H, Minamino T, Kato S, Sakagami H, Shibuya M, Majima M.
- Journal Title
  
  Toxicol Sci.
  
  Volume: 120(1) Pages: 218-229
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Journal Article] Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation2011
- Author(s)
  Hosono K, Suzuki T, Tamaki H, Sakagami H, Hayashi I, Narumiya S, Alitalo K, Majima M
- Journal Title
  
  Arterioscler Thromb Vasc Biol
  
  Volume: 31(5) Issue: 5 Pages: 1049-58
- DOI
  10.1161/atvbaha.110.222356
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390072, KAKENHI-PROJECT-22300114, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-23659101, KAKENHI-PROJECT-23790302
[Journal Article] Role of COX-2 in lymphangiogenesis and restoration of lymphatic flow in secondary lymphedema2011
- Author(s)
  Kashiwagi S, et.al.
- Journal Title
  
  Lab Invest
  
  Volume: 91(9) Issue: 9 Pages: 1314-1325
- DOI
  10.1038/labinvest.2011.84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390072, KAKENHI-PLANNED-23116102, KAKENHI-PROJECT-23790302
[Journal Article] Microsomal prostaglandin E synthase-1 enhances bone cancer growth and bone cancer-related pain behaviors in mice.2011
- Author(s)
  Isono M, Suzuki T, Hosono K, Hayashi I, Sakagami H, Uematsu S, Akira S, DeClerck YA, Okamoto H, Majima M.
- Journal Title
  
  Life Sci.
  
  Volume: 88(15-16) Pages: 693-700
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23790302
[Presentation] RAMP1シグナル欠損は食事誘導脂肪性肝疾患を増悪する2023
- Author(s)
  伊藤義也、細野加奈子、別當朋広、田邉美奈、山下敦、黒田悠、鎌田真理子、畑中公、馬嶋正隆、天野英樹
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06651
[Presentation] RAMP1シグナルの欠損は、食餌誘発性肥満と腸乳管を介した脂肪吸収を促進する2023
- Author(s)
  細野加奈子、伊藤義也、別當朋広、田邉美奈、山下敦、鎌田真理子、畑中公、馬嶋正隆、天野英樹
- Organizer
  第97回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06651
[Presentation] 腸管脂肪吸収における神経ペプチドCGRPの役割解明2022
- Author(s)
  細野加奈子、伊藤義也、別當朋広、畑中公、馬嶋正隆、天野英樹
- Organizer
  第96回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-22K06651
[Presentation] RAMP1シグナルの脂肪肝内炎症抑制効果2021
- Author(s)
  伊藤義也、細野加奈子、後藤卓也、田邊美奈、山下敦、長田真由子、畑中公、馬嶋正隆、天野英樹
- Organizer
  第145回日本薬理学会関東部会
- Data Source
  KAKENHI-PROJECT-19K07127
[Presentation] マウス子宮内膜症におけるRAMP1の血管・リンパ管新生促進作用2020
- Author(s)
  本田　雅子，伊藤　義也，服部　響子，細野加奈子，中本　修司,大高　史聖，津留　世里，馬嶋　正隆
- Organizer
  第41回炎症再生医学会
- Data Source
  KAKENHI-PROJECT-19K07127
[Presentation] CGRP/RAMP1によるリンパ管新生増強作用2020
- Author(s)
  細野加奈子、伊藤義也、馬嶋正隆
- Organizer
  日本薬理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02605
[Presentation] TP signaling in immune cells promotes lymphangiogenesis in the diaphragm during peritonitis2020
- Author(s)
  津留世里、伊藤義也、松田弘美、細野加奈子、岡本浩嗣、馬嶋正隆
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K07127
[Presentation] RAMP1 signaling facilitates angiogenesis and lymphangiogenesis in the endometriotic lesions in mice2020
- Author(s)
  本田雅子、伊藤義也、服部響子、細野加奈子、中本修司、大高史聖、津留世里、馬嶋正隆
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K07127
[Presentation] Neuropeptide CGRP regulates inflammation by increasing lymphangiogenesis2020
- Author(s)
  細野加奈子、伊藤義也、天野英樹、馬嶋正隆
- Organizer
  第93回日本薬理学会
- Data Source
  KAKENHI-PROJECT-19K07127
[Presentation] TPシグナリングによるリンパ管新生増強作用2020
- Author(s)
  細野加奈子、馬嶋正隆
- Organizer
  第 44 回日本リンパ学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-18H02605
[Presentation] 腹膜炎時の横隔膜リンパ管新生を制御する受容体活性調節蛋白１(RAMP1)の役割2019
- Author(s)
  津留世里、伊藤義也、細野加奈子、井上智仁、松田弘美、藏重千絵、中本修司、大高史聖、岡本浩嗣、馬嶋正隆
- Organizer
  第40回日本炎症再生医学会
- Data Source
  KAKENHI-PROJECT-19K07127
[Presentation] リンパ管新生を制御する神経ペプチドCGRPの役割2019
- Author(s)
  伊藤義也、津留世里、細野加奈子、天野英樹、馬嶋正隆
- Organizer
  第43回日本リンパ学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K07127
[Presentation] 病態時のリンパ管新生を制御する脂質メディエーターの役割2017
- Author(s)
  細野加奈子、松田弘美、馬嶋正隆
- Organizer
  第41回日本リンパ学会総会
- Data Source
  KAKENHI-PROJECT-15K08241
[Presentation] リンパ管・リンパ組織の可塑性を制御する生理活性脂質の役割2016
- Author(s)
  馬嶋正隆、天野英樹、細野加奈子
- Organizer
  第40回日本リンパ学会総会
- Place of Presentation
  東京大学　伊藤国際学術研究センター(東京都文京区)
- Year and Date
  2016-06-24
- Invited
- Data Source
  KAKENHI-PROJECT-15K08241
[Presentation] Signaling of prostaglandin E receptors, EP3 and EP4 facilitates wound healing and lymphangiogenesis with enhanced recruitment of CD11b+ macrophages in mice2016
- Author(s)
  Hosono Kanako, Isonaka Risa , Kawakami Tadashi, Narumiya Shuh, Majima Masataka
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜市西区）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08241
[Presentation] Role of TP signaling in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis model2016
- Author(s)
  Matsuda Hiromi, Hosono Kanako, Tsuru Seri, Narumiya Shuh, Majima Masataka
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜市西区）
- Year and Date
  2016-03-09
- Data Source
  KAKENHI-PROJECT-15K08241
[Presentation] Roles of Prostaglandins in regulation of plasticity of lymphatics and lymph nodes2016
- Author(s)
  Majima Masataka, Hosono Kanako, Amano Hideki, Fujita Tomoe
- Organizer
  第89回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜（横浜市西区）
- Year and Date
  2016-03-09
- Invited
- Data Source
  KAKENHI-PROJECT-15K08241
[Presentation] エンドトキシン誘発腹膜炎マウスの横隔膜リンパ管新生を増強するトロンンボキサン受容体シグナリングの役割2016
- Author(s)
  松田弘美，細野加奈子，馬嶋正隆
- Organizer
  第40回日本リンパ学会総会
- Place of Presentation
  東京大学　伊藤国際学術研究センター(東京都文京区)
- Year and Date
  2016-06-24
- Data Source
  KAKENHI-PROJECT-15K08241
[Presentation] RAMP-1シグナルによる創傷治癒および血管新生の増強2013
- Author(s)
  藏重千絵、細野加奈子、松田弘美、馬嶋正隆
- Organizer
  86th Jap Pharmacological Society Annual Meeting
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] 肝虚血再還流後肝再生に果たすロイコトリエンB4とその受容体の働き2013
- Author(s)
  大久保博世、伊藤義也、細野加奈子、馬嶋正隆
- Organizer
  86th Jap Pharmacological Society Annual Meeting
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] Role of VEGFR1 signaling in liver injury and repair following hepatic ischemia/reperfusion injury in mice2013
- Author(s)
  Ohkubo H, Ito Y, Minamino T, Hosono K, Watanabe M, Majima M
- Organizer
  第38回日本微小循環学会総会
- Place of Presentation
  Tokyo
- Year and Date
  2013-02-07
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] Role of COX-2 in enhancement of lymphangiogenesis in diaphragm after the peritoneal application of endotoxin2013
- Author(s)
  松田弘美、細野加奈子、蔵重千絵、馬嶋正隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23790302
[Presentation] エンドトキシン誘発性腹膜炎時のCOX-2依存性のリンパ管新生2013
- Author(s)
  松田弘美、藏重千絵、細野加奈子、馬嶋正隆
- Organizer
  86th Jap Pharmacological Society Annual Meeting
- Place of Presentation
  福岡
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] 創傷治癒時のリンパ管新生におけるプロスタグランジン E2 およびその受容体シグナリングの役割2012
- Author(s)
  細野加奈子、鈴木立紀、成宮周、馬嶋正隆
- Organizer
  第126回日本薬理学会関東部会
- Place of Presentation
  東京
- Year and Date
  2012-07-14
- Data Source
  KAKENHI-PROJECT-23790302
[Presentation] Role of cyclooxygenase-2 in enhancement of lymphangiogenesis during wound healing2012
- Author(s)
  細野加奈子、鈴木立紀、成宮周、馬嶋正隆
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790302
[Presentation] Roles of prostaglandin E2-EP3/EP4 receptor signalings in enhancement of lymphangiogenesis during inflammation2012
- Author(s)
  細野加奈子、馬嶋正隆
- Organizer
  第36回リンパ学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790302
[Presentation] Role of cyclooxygenase-2 in enhancement of lymphangiogenesis during wound healing2012
- Author(s)
  〇細野加奈子、鈴木立紀、成宮周、馬嶋正隆
- Organizer
  第８５回日本薬理学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23790302
[Presentation] 受容体活性調節蛋白1(RAMP1)シグナルによる創傷治癒および脈管新生の増強
- Author(s)
  藏重　千絵，細野加奈子，松田　弘美，馬嶋　正隆
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25860192
[Presentation] 肺癌リンパ節転移およびpremetastatic niche形成におけるプロスタグランジンの役割
- Author(s)
  小川史洋, 天野英樹, 細野加奈子, 熊谷雄治, 馬嶋正隆
- Organizer
  第38回日本リンパ学会総会
- Place of Presentation
  北里大学白金キャンパス（東京都港区）
- Year and Date
  2014-06-20 – 2014-06-22
- Data Source
  KAKENHI-PROJECT-25860192
[Presentation] Role of Dendritic Cells via COX-2 Derived PGE2-EP3 Signaling for Pre-metastatic Niche Formation in Lymph Node Metastasis on Lung Cancer　（肺癌リンパ節転移でのPre-metastastatic nicheにおけるCOX-2誘導性PGE2-EP3シグナリングを介した樹状細胞の役割）
- Author(s)
  小川史洋、天野英樹、江島耕二、細野加奈子、佐藤之俊、成宮周、熊谷雄二、馬嶋正隆
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25860192
[Presentation] Microsomal prostaglandin E synthase-1 as a regulator of angiogenesis
- Author(s)
  Majima M., Hosono K., Suzuki T., Amano H.
- Organizer
  GRC Angiogenesis
- Place of Presentation
  New Port (United States)
- Invited
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] Pre-metastatic niche 形成における樹状細胞 -PGE2-EP3 signaling,SDF-1/TGF-β の役割
- Author(s)
  小川史洋, 天野英樹, 細野加奈子, 熊谷雄治, 成宮周, 馬嶋正隆
- Organizer
  第35回日本炎症・再生医学会
- Place of Presentation
  万国津梁館(沖縄県名護市）
- Year and Date
  2014-07-01 – 2014-07-04
- Data Source
  KAKENHI-PROJECT-25860192
[Presentation] Prostanoids regulate tumor stromal profiles via specific G-protein coupled receptors
- Author(s)
  Majima M., Hosono K., Suzuki T., Amano H., Kato H., Ogawa F., Park K.
- Organizer
  4th International conference on tumor-host interaction and Angiogenesis
- Place of Presentation
  Ascona (Switzerland)
- Invited
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] Roles of Prostanoids in Regulation of Angiogenesis and Lymphangiogenesis
- Author(s)
  Majima M., Hosono K., Suzuki T., Amano H.
- Organizer
  The 16th GEM-10th GERLI meeting: from membranes to pathologies
- Place of Presentation
  Saint-Jean Cap Ferrat　(France)
- Invited
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] Role of COX-2 and TP signaling in lenhancement of lymph angiogenesis in diaphragm in endotoxins -induced peritonitis (エンドトキシン誘発性腹膜炎マウスの横隔膜リンパ管新生におけるCOX-2とTPシグナリングの役割)
- Author(s)
  松田弘美、細野加奈子、藏重千絵、成宮周、馬嶋正隆
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-25860192
[Presentation] 創傷治癒時のリンパ管新生におけるプロスタグランジンE2およびその受容体シグナリングの役割
- Author(s)
  〇細野加奈子、鈴木立紀、成宮周、馬嶋正隆
- Organizer
  第126回日本薬理学会関東部会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23790302
[Presentation] Prostanoids as Regulators of Pathological Lymphangiogenesis
- Author(s)
  Majima M., Hosono K., Amano H., Ogawa F., Park K.
- Organizer
  GRC Molecular Mechanisms in Lymphatic Function & Diseas
- Place of Presentation
  Lucca (Italy)
- Invited
- Data Source
  KAKENHI-PLANNED-23116102
[Presentation] 創傷治癒時のリンパ管新生を制御するプロスタグランジンE2受容体シグナリングの役割
- Author(s)
  細野加奈子，成宮　　周，馬嶋　正隆
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25860192
[Presentation] エンドトキシン誘発性腹膜炎マウスの横隔膜リンパ管新生におけるCOX-2の役割
- Author(s)
  松田　弘美，細野加奈子，藏重　千絵，馬嶋　正隆
- Organizer
  第34回日本炎症・再生医学会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-25860192
[Presentation] 病態時のリンパ管新生を制御するプロスタグランジンの役割
- Author(s)
  細野加奈子, 松田弘美, 朴圭一, 馬嶋正隆
- Organizer
  第38回日本リンパ学会総会
- Place of Presentation
  北里大学白金キャンパス（東京都港区）
- Year and Date
  2014-06-20 – 2014-06-22
- Data Source
  KAKENHI-PROJECT-25860192

1. MAJIMA Masataka (70181641)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
2. 伊藤義也 (40203187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
3. FUJITA Tomoe (20296510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 天野英樹 (60296481)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
5. 横溝岳彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 鈴木立紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HOSONO KANAKO 細野 加奈子

HOSONO Kanako 細野 加奈子

Research Projects

Research Products

Co-Researchers

肥満炎症性腸疾患の粘膜修復を制御する知覚神経―免疫細胞相互作用Principal Investigator

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脂肪肝炎と腸管脂肪吸収とを制御する神経―免疫クロストークの役割解明Principal Investigator

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The role of calcitonin gene-related peptide (CGRP) in regulation of intestinal fat absorptionPrincipal Investigator

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Bioactive lipids as regulators of plasticity of lymphatics

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Role of TP signaling in enhancement of LPS-induced lymphangiogenesis in a mouse peritonitis modelPrincipal Investigator

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Roles of prostanoid during premetastatic niche formation in regional lymph nodePrincipal Investigator

Principal Investigator

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Roles of prostanoids in facilitation of lymphangiogenesis and lymph node metastasis

Principal Investigator

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Role of prostaglandin receptor signaling inenhancement of lymphangiogenesis and application to metastasis treatmentPrincipal Investigator

Principal Investigator

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[Book] 実験医学2017

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[Book] 炎症と免疫2016

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[Journal Article] Deletion of RAMP1 Signaling Enhances Diet-induced Obesity and Fat Absorption via Intestinal Lacteals in Mice2023

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[Journal Article] Biologically active lipids in the regulation of lymphangiogenesis in disease states2022

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[Journal Article] Roles of Thromboxane Receptor Signaling in Enhancement of Lipopolysaccharide-Induced Lymphangiogenesis and Lymphatic Drainage Function in Diaphragm.2021

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[Journal Article] Prostaglandin E receptor EP4 stimulates lymphangiogenesis to promote mucosal healing during DSS-induced colitis2020

Author(s)

HOSONO KANAKO 細野加奈子

HOSONO Kanako 細野加奈子

[Journal Article] 特集血管制御系と疾患生理活性脂質と脈管新生2017