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HATAYAMA Naoyuki  畑山 直之

ORCIDConnect your ORCID iD *help
Researcher Number 80534792
Other IDs
Affiliation (Current) 2025: 愛知医科大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 愛知医科大学, 医学部, 准教授
2017 – 2020: 愛知医科大学, 医学部, 講師
2016: 愛知医科大学, 医学部, 助教
2012 – 2015: 東京医科大学, 医学部, 助教
2013: 東京医科大学, 人体構造学講座, 助教 … More
2011: (独)国立成育医療研究センター, RI管理室, 共同研究員
2010: 独立行政法人国立成育医療研究センター, RI管理室, 共同研究員
2010: 独立行政法人国立成育医療研究センター, 研究所・RI管理室, 共同研究員
2009: 国立成育医療センター(研究所), 移植・外科研究部, 共同研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / Digestive surgery / Plastic surgery / General surgery
Except Principal Investigator
Basic Section 53040:Nephrology-related / Basic Section 90130:Medical systems-related / General surgery / Basic Section 54010:Hematology and medical oncology-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 58050:Fundamental of nursing-related … More / Rehabilitation science/Welfare engineering / Legal medicine / Medical sociology / General anatomy (including histology/embryology) / Laboratory animal science / Radiation science Less
Keywords
Principal Investigator
虚血再灌流障害 / 酸素 / 一酸化炭素 / ラット / 臓器保存 / ウルトラファインバブル / イヌ / 高圧ガス保存法 / 高圧ガス保存 / ブタ … More / 肝臓 / ガスメディエータ / 移植 / マウス / 虚血再還流障害 / 腎臓 / 肺 / 小腸 / ラット切断肢 / 保存 / ガス保存法 / 笑気ガス / キセノン / 四肢 / 高圧ガス / 再建外科学 / 乾燥 / 高圧 / 移植・再生医療 / 移植外科学 … More
Except Principal Investigator
腹膜透析 / 移植 / メディカルガス / 精巣上体 / 精巣 / 再灌流障害 / 超微細気泡 / 洗浄血小板 / CORM-2 / 内因性生理活性ガスUFB / α顆粒膜GPⅡb/Ⅲa / lipopolysaccharide (LPS) / CO-Dissolve / 血小板保存液 / 一酸化炭素 / 血小板 / 腹膜透過性 / 抗VEGF抗体 / ヒアルロニダーゼ / TMA / 妊娠高血圧症候群 / ヒアルロン酸 / 蛋白尿 / 糸球体内皮細胞 / Glycocalyx / 解剖 / 尿素 / 御遺体処置法 / 肉眼解剖 / CST / 肉眼解剖学 / 感染予防 / 洗浄・殺菌 / ファインバブル / ガス送達システム / 移植医療 / 内因性生理活性ガス / 移植用臓器保存法 / 人体解剖モデル / コメディカル教育 / リハビリテーション / 診断 / 外傷 / 肩関節 / シミュレータ / 医学教育 / 解剖学 / ガス / 臓器保存 / セロトニン / 硫化水素 / 間歇低酸素 / 間歇的低酸素 / 睡眠時無呼吸 / 呼吸中枢 / 低酸素 / 睡眠時無呼吸症候群 / プリザーブ法 / Thiel法 / 尿素法 / SSS法 / ホルムアルデヒド(FA ) / 低減 / 固定 / 防腐 / ホルムアルデヒド(FA) / 異性間移植 / 免疫特権 / 異所性移植 / ラット / 抗原解析 / 自己免疫疾患 / 精子抗原 / マウス / タンパク質同定 / 自己抗原 / 自己免疫性精巣炎 / 精子形成 / 再生治療 / 心臓移植 / 再生医療 / 遺伝子治療 / 循環器 / 分子イメージング / 核医学(PETを含む) / 細胞・組織 / 遺伝子 / 移植・再生医療 Less
  • Research Projects

    (20 results)
  • Research Products

    (73 results)
  • Co-Researchers

    (65 People)
  •  移植臓器の体外治療を目指した新たな生理活性ガス送達技術の確立Principal Investigator

    • Principal Investigator
      畑山 直之
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Aichi Medical University
  •  Establishment of a method to reduce ischemia-reperfusion injury using ultrafine bubbles

    • Principal Investigator
      内藤 宗和
    • Project Period (FY)
      2022 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Aichi Medical University
  •  内皮細胞Glycocalyxをターゲットとした腎疾患の新たな治療戦略の確立

    • Principal Investigator
      伊藤 恭彦
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Aichi Medical University
  •  Development of a new platelet preservation solution using endogenous bioactive gases

    • Principal Investigator
      Yakura Tomiko
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Tokyo Medical University
  •  Development of prevention and treatment methods for peritoneal deterioration using gaseous transmitters in peritoneal dialysis

    • Principal Investigator
      Kamiya Keisuke
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Aichi Medical University
  •  Development of new treatment methods, management and operation systems that enable multi-purpose use of cadavers.

    • Principal Investigator
      HIRAI Shuichi
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 58:Society medicine, nursing, and related fields
    • Research Institution
      Nihon University
      Aichi Medical University
  •  Application of gas mediator delivery system for the expanded criteria donor organsPrincipal Investigator

    • Principal Investigator
      Hatayama Naoyuki
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Aichi Medical University
  •  Endogenous Physiological Gas Delivery System and Its Application to Transplantation Medicine

    • Principal Investigator
      HIRAI Shuichi
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Nihon University
      Aichi Medical University
  •  Research on the conditions of fine bubbles suitable for cleaning and sterilizing medical device and the hand hygiene

    • Principal Investigator
      shinoda kaoru
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 58050:Fundamental of nursing-related
    • Research Institution
      Aichi Medical University
  •  Establishment of a new organ preservation method using high-pressure medical gas

    • Principal Investigator
      Naito Munekazu
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General surgery
    • Research Institution
      Aichi Medical University
  •  Development of high-quality shoulder joint dislocation simulation model for acquiring inspection and palpation techniques

    • Principal Investigator
      Hayashi Shogo
    • Project Period (FY)
      2017 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Rehabilitation science/Welfare engineering
    • Research Institution
      Tokai University
      International University of Health and Welfare
  •  Hydrogen sulfide and Serotonin in sleep apnea syndrome

    • Principal Investigator
      HIRAI SHUICHI
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Legal medicine
    • Research Institution
      Aichi Medical University
  •  The application of high pressure gas preservation method in small intestine transplantationPrincipal Investigator

    • Principal Investigator
      Hatayama Naoyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Digestive surgery
    • Research Institution
      Aichi Medical University
      Tokyo Medical University
  •  Immunosuppressive microenvironment in the testicular tissues

    • Principal Investigator
      Itoh Masahiro
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General anatomy (including histology/embryology)
    • Research Institution
      Tokyo Medical University
  •  Trials for foundation of cadaver preservation

    • Principal Investigator
      Kawata Shinichi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Medical sociology
    • Research Institution
      Tokyo Medical University
  •  Elucidation of mechanisms of high pressure gas preservation method for clinical application in amputated limb preservationPrincipal Investigator

    • Principal Investigator
      Hatayama Naoyuki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Plastic surgery
    • Research Institution
      Tokyo Medical University
  •  Establishment of a highly reproducible model of immunological male infertility with analyses of related testicular autoantigens

    • Principal Investigator
      ITOH Masahiro
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Laboratory animal science
    • Research Institution
      Tokyo Medical University
  •  Molecular Imaging Research for Forefront of Cardiovascular Medicine

    • Principal Investigator
      INUBUSHI Masayuki
    • Project Period (FY)
      2010 – 2013
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Radiation science
    • Research Institution
      Kawasaki Medical School
      National Institute of Radiological Sciences
  •  The establishment of a high-pressure gas preservation method, and the elucidation of mechanism.Principal Investigator

    • Principal Investigator
      HATAYAMA Naoyuki
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      General surgery
    • Research Institution
      Tokyo Medical University
      National Research Institute for Child Health and Development
  •  iPS細胞を用いた制御性樹状細胞への分化誘導および免疫細胞療法の開発に関する研究

    • Principal Investigator
      LI Xiao-kang
    • Project Period (FY)
      2009 – 2010
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      General surgery
    • Research Institution
      National Research Institute for Child Health and Development

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation Patent

  • [Journal Article] Machine perfusion preservation of donor livers and their target temperature2022

    • Author(s)
      秦 浩一郎、藤分 秀司、波多野 悦朗、宮内 英孝、田嶋 哲也、趙 向東、日下部 治郎、畑山 直之、内藤 宗和、國光 健、樫原 稔
    • Journal Title

      Organ Biology

      Volume: 29 Issue: 1 Pages: 21-28

    • DOI

      10.11378/organbio.29.21

    • NAID

      130008162273

    • ISSN
      1340-5152, 2188-0204
    • Language
      Japanese
    • Open Access
    • Data Source
      KAKENHI-PROJECT-19K09108
  • [Journal Article] Efficacy of urea solution reperfusion to a formalin-embalmed cadaver for surgical skills training2022

    • Author(s)
      Otsuka Shun、Kawata Shinichi、Nanizawa Eri、Hatayama Naoyuki、Hayashi Shogo、Itoh Masahiro、Hirai Shuichi、Naito Munekazu
    • Journal Title

      Anatomical Science International

      Volume: Online ahead of print. Issue: 3 Pages: 264-272

    • DOI

      10.1007/s12565-022-00653-y

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09108, KAKENHI-PROJECT-20K21735
  • [Journal Article] The effect of simulation‐based education before a cadaver dissection course2021

    • Author(s)
      Yakura Tomiko、Hatayama Naoyuki、Kawahara Chikako、Ohmichi Yusuke、Ohmichi Mika、Ban Nobutaro、Hirai Shuichi、Nakano Takashi、Naito Munekazu
    • Journal Title

      Anatomical Sciences Education

      Volume: 15 Issue: 2 Pages: 392-402

    • DOI

      10.1002/ase.2124

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09108
  • [Journal Article] Heat shock protein A4L is a potent autoantigen for testicular autoimmunity in mice2021

    • Author(s)
      Nagahori Kenta、Hirai Shuichi、Hatayama Naoyuki、Kuramasu Miyuki、Omotehara Takuya、Kawata Shinichi、Li Zhonglian、Miyaso Hidenobu、Ogawa Yuki、Qu Ning、Terayama Hayato、Hayashi Shogo、Yi Shuang-Qin、Naito Munekazu、Itoh Masahiro
    • Journal Title

      Journal of Reproductive Immunology

      Volume: 145 Pages: 103318-103318

    • DOI

      10.1016/j.jri.2021.103318

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K16483, KAKENHI-PROJECT-19K09108, KAKENHI-PROJECT-19K18572, KAKENHI-PROJECT-19K07271, KAKENHI-PROJECT-19K07876, KAKENHI-PROJECT-21K11227
  • [Journal Article] Roles of glomerular endothelial hyaluronan in the development of proteinuria2021

    • Author(s)
      Asai Akimasa、Hatayama Naoyuki、Kamiya Keisuke、Yamauchi Mai、Kinashi Hiroshi、Yamaguchi Makoto、Katsuno Takayuki、Nobata Hironobu、Watanabe Kazushi、Wakatsuki Akihiko、Aten Jan、Maruyama Shoichi、Ishimoto Takuji、Hirai Shuichi、Naito Munekazu、Ito Yasuhiko
    • Journal Title

      Physiological Reports

      Volume: 9 Issue: 17

    • DOI

      10.14814/phy2.15019

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09108, KAKENHI-PROJECT-21K08254, KAKENHI-PROJECT-21K08291
  • [Journal Article] Cardioprotection via Metabolism for Rat Heart Preservation Using the High-Pressure Gaseous Mixture of Carbon Monoxide and Oxygen2020

    • Author(s)
      Suzuki C, Hatayama N, Ogawa T, Nanizawa E, Otsuka S, Hata K, Seno H, Naito M, Hirai S.
    • Journal Title

      Int J Mol Sci

      Volume: 21(22) Issue: 22 Pages: 8858-8858

    • DOI

      10.3390/ijms21228858

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09108, KAKENHI-PROJECT-17H04274, KAKENHI-PROJECT-19H04493
  • [Journal Article] High-Pressure Carbon Monoxide and Oxygen Mixture is Effective for Lung Preservation2019

    • Author(s)
      Fujiwara Atsushi、Hatayama Naoyuki、Matsuura Natsumi、Yokota Naoya、Fukushige Kaori、Yakura Tomiko、Tarumi Shintaro、Go Tetsuhiko、Hirai Shuichi、Naito Munekazu、Yokomise Hiroyasu
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 20 Issue: 11 Pages: 2719-2719

    • DOI

      10.3390/ijms20112719

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09108, KAKENHI-PROJECT-17H04274
  • [Journal Article] Different effects of partial pressure in a high-pressure gaseous mixture of carbon monoxide and oxygen for rat heart preservation2019

    • Author(s)
      Hatayama Naoyuki、Hirai Shuichi、Fukushige Kaori、Yokota Hiroki、Itoh Masahiro、Naito Munekazu
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 7480-7480

    • DOI

      10.1038/s41598-019-43905-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09108, KAKENHI-PROJECT-17H04274
  • [Journal Article] Preservation of rat limbs by hyperbaric carbon monoxide and oxygen2018

    • Author(s)
      Hatayama Naoyuki、Hirai Shuichi、Naito Munekazu、Terayama Hayato、Araki Jun、Yokota Hiroki、Matsushita Masayuki、Li Xiao-Kang、Itoh Masahiro
    • Journal Title

      Scientific Reports

      Volume: 8 Issue: 1 Pages: 6627-6627

    • DOI

      10.1038/s41598-018-25070-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17H04274, KAKENHI-PROJECT-15K10151, KAKENHI-PROJECT-18K10031, KAKENHI-PROJECT-16K09219
  • [Journal Article] High-pressure carbon monoxide preserves rat kidney grafts from apoptosis and inflammation2017

    • Author(s)
      Abe Toyofumi、Yazawa Koji、Fujino Masayuki、Imamura Ryoichi、Hatayama Naoyuki、Kakuta Yoichi、Tsutahara Koichi、Okumi Masayoshi、Ichimaru Naotsugu、Kaimori Jun-ya、Isaka Yoshitaka、Seki Kunihiro、Takahara Shiro、Li Xiao-Kang、Nonomura Norio
    • Journal Title

      Laboratory Investigation

      Volume: 97 Issue: 4 Pages: 468-477

    • DOI

      10.1038/labinvest.2016.157

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10043, KAKENHI-PROJECT-15K10151, KAKENHI-PROJECT-17H04277
  • [Journal Article] Pathological effect of arterial ischaemia and venous congestion on rat testes2017

    • Author(s)
      Hirai S, Hatayama N, Naito M, Nagahori K, Kawata S, Hayashi S, Qu N, Terayama H, Shoji S, Itoh M
    • Journal Title

      Sci Rep.

      Volume: 14;7(1) Issue: 1 Pages: 5422-5422

    • DOI

      10.1038/s41598-017-05880-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08937, KAKENHI-PROJECT-15K10151, KAKENHI-PROJECT-26460809
  • [Journal Article] Development of heterotopic transplantation of the testis with the epididymis to evaluate an aspect of testicular immunology in rats2017

    • Author(s)
      Yi K, Hatayama N, Hirai S, Qu N, Hayashi S, Kawata S, Nagahori K, Naito M, Itoh M.
    • Journal Title

      PLoS One

      Volume: 12(5) Issue: 5 Pages: e0177067-e0177067

    • DOI

      10.1371/journal.pone.0177067

    • NAID

      120006591011

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K08159, KAKENHI-PROJECT-15K08937, KAKENHI-PROJECT-15K10151
  • [Journal Article] A novel classification of musculocutaneous nerve variations: The relationship between the communicating branch and transposed innervation of the brachial flexors to the median nerve.2017

    • Author(s)
      Hayashi M, Shionoya K, Hayashi S, Hatayama N, Kawata S, Qu N, Hirai S, Miyaso H, Itoh M
    • Journal Title

      Annals of Anatomy

      Volume: 209 Pages: 45-50

    • DOI

      10.1016/j.aanat.2016.08.004

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K10151
  • [Journal Article] Morphological study of the neurovascular bundle to elucidate nerve damage in pelvic surger2016

    • Author(s)
      Nishimura M, Nishizawa Y, Naito M, Hirai S, Itoh M, Ito M, Akamoto S, Suzuki Y
    • Journal Title

      Int J Colorectal Dis.

      Volume: 31(3) Issue: 3 Pages: 503-9

    • DOI

      10.1007/s00384-015-2470-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462019, KAKENHI-PROJECT-16K09219
  • [Journal Article] Specific autoantigens identified by sera obtained from mice that are immunized with testicular germ cells alone.2016

    • Author(s)
      Terayama H, Hirai S, Naito M, Qu N, Katagiri C, Nagahori K, Hayashi S, Sasaki H, Moriya S, Hiramoto M, Miyazawa K, Hatayama N, Li ZL, Sakabe K, Matsushita M, Itoh M.
    • Journal Title

      Sci Rep.

      Volume: 18 Issue: 1 Pages: 35599-35599

    • DOI

      10.1038/srep35599

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26460478, KAKENHI-PROJECT-15K08937, KAKENHI-PROJECT-16K09219, KAKENHI-PROJECT-26460809, KAKENHI-PROJECT-16K19187
  • [Journal Article] Functional evaluation of rat hearts transplanted after preservation in a high-pressure gaseous mixture of carbon monoxide and oxygen.2016

    • Author(s)
      Hatayama N, Inubushi M, Naito M, Hirai S, Jin YN, Tsuji AB, Seki K, Itoh M, Saga T, Li XK..
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 32120-32120

    • DOI

      10.1038/srep32120

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293282, KAKENHI-PROJECT-26460992, KAKENHI-PROJECT-15K09976, KAKENHI-PROJECT-16K09219
  • [Journal Article] History and future of human cadaver preservation for surgical training: from formalin to saturated salt solution method2016

    • Author(s)
      Shogo Hayashi, Munekazu Naito, Shinichi Kawata, Ning Qu, Naoyuki Hatayama, Shuichi Hirai, Masahiro Itoh
    • Journal Title

      Anatomical Science International

      Volume: 91 Issue: 1 Pages: 1-7

    • DOI

      10.1007/s12565-015-0299-5

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26463257, KAKENHI-PROJECT-26670254
  • [Journal Article] Busulfan pretreatment for transplantation of rat spermatogonia differentially affects immune and reproductive systems in male recipient mice.2015

    • Author(s)
      Hirayanagi Y, Qu N, Hirai S, Naito M, Terayama H, Hayashi S, Hatayama N, Kuramasu M, Ogawa Y, Itoh M.
    • Journal Title

      Anat Sci Int.

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Journal Article] Neonatal estrogen treatment with β-estradiol 17-cypionate induces in post-pubertal mice inflammation in the ductuli efferentes, epididymis, and vas deferens, but not in the testis, provoking obstructive azoospermia.2014

    • Author(s)
      Naito M, Hirai S, Terayama H, Qu N, Hayashi S, Hatayama N, Kawamura H, Nakano T, Itoh M.
    • Journal Title

      Med Mol Morphol.

      Volume: 47 Issue: 1 Pages: 21-30

    • DOI

      10.1007/s00795-013-0034-z

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23500504, KAKENHI-PROJECT-24590243
  • [Journal Article] Contribution of IL-12/IL-35 common subunit p35 to maintaining the testicular immune privilege2014

    • Author(s)
      Terayama H, Yoshimoto T, Hirai S, Naito M, Qu N, Hatayama N, Hayashi S, Mitobe K, Furusawa J, Mizoguchi I, Kezuka T, Goto H, Suyama K, Moriyama H, Sakabe K, Itoh M.
    • Journal Title

      PLoS One

      Volume: 9 Issue: 4 Pages: e96120-e96120

    • DOI

      10.1371/journal.pone.0096120

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-23500504, KAKENHI-PROJECT-24370058, KAKENHI-PROJECT-24590243, KAKENHI-PROJECT-24790091, KAKENHI-PROJECT-24791234, KAKENHI-PUBLICLY-25118727
  • [Journal Article] Saturated salt solution method: a useful cadaver embalming for surgical skills training2014

    • Author(s)
      Hayashi S, Homma H, Naito M, Oda J, Nishiyama T, Kawamoto A, Kawata S, Sato N, Fukuhara T, Taguchi H, Mashiko K, Azuhata T, Ito M, Kawai K, Suzuki T, Nishizawa Y, Araki J, Matsuno N, Shirai T, Qu N, Hatayama N, Hirai S, Fukui H, Ohseto K, Yukioka T, Itoh M.
    • Journal Title

      Medicine

      Volume: 93 Issue: 27 Pages: e196-e196

    • DOI

      10.1097/md.0000000000000196

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23390134, KAKENHI-PROJECT-26463257, KAKENHI-PROJECT-26670254
  • [Journal Article] The Effects of Adjuvants on Autoimmune Responses Against Testicular Antigens in Mice2013

    • Author(s)
      Musha M, Hirai S, Naito M, Terayama H, Qu N, Hatayama N, Itoh M.
    • Journal Title

      J. Reprod. Dev.

      Volume: 59 Issue: 2 Pages: 139-144

    • DOI

      10.1262/jrd.2012-121

    • NAID

      10031170771

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Journal Article] 臓器保存におけるメディカルガスの可能性:一酸化炭素(CO)と酸素(O2)を用いた高圧保存法2013

    • Author(s)
      畑山 直之、平井 宗一、内藤 宗和、寺山 隼人、曲 寧、伊藤 正裕
    • Journal Title

      Organ Biology

      Volume: Vol.20, (印刷中)

    • Data Source
      KAKENHI-PROJECT-22791266
  • [Journal Article] 臓器保存におけるメディカルガスの可能性:一酸化炭素(CO)と酸素(O2)を用いた高圧保存法2013

    • Author(s)
      畑山直之
    • Journal Title

      Organ Biology

      Volume: Vol.20 No.2

    • Data Source
      KAKENHI-PROJECT-22791266
  • [Journal Article] Effects on the Local Immunity in the Testis by Exposure to Di-(2-ethylhexyl) Phthalate (DEHP) in Mice2013

    • Author(s)
      Kitaoka M, Hirai S, Terayama H, Naito M, Qu N, Hatayama N, Miyaso H, Matsuno Y, Komiyama M, Itoh M, Mori C.
    • Journal Title

      J. Reprod. Dev.

      Volume: 59 Issue: 5 Pages: 485-490

    • DOI

      10.1262/jrd.2012-180

    • NAID

      130003361051

    • ISSN
      0916-8818, 1348-4400
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Journal Article] The effects of adjuvants on autoimmune responses against testicular antigens in mice2012

    • Author(s)
      Musha M, Hirai S, Naito M, Terayama H, Qu N, Hatayama N, Itoh M
    • Journal Title

      Journal of Reproduction and Development

      Volume: 59(2) Pages: 139-144

    • NAID

      10031170771

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Patent] 組成物,甘味付与組成物,風味改善組成物,微小気泡を含む対象物の製造方法,甘味付与方法,風味改善方法,飲食品,および飲食品の製造方法.2018

    • Inventor(s)
      畑山直之, 内藤宗和, 平井宗一, 坂上茂樹.
    • Industrial Property Rights Holder
      畑山直之, 内藤宗和, 平井宗一, 坂上茂樹.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K09219
  • [Patent] 組成物,細胞保存組成物,細胞培養組成物,細胞製剤,微小気泡を含む対象物の製造方法,細胞の保存方法,細胞の培養方法,および細胞製剤の製造方法2018

    • Inventor(s)
      畑山直之, 内藤宗和, 平井宗一, 坂上茂樹.
    • Industrial Property Rights Holder
      畑山直之, 内藤宗和, 平井宗一, 坂上茂樹.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K09219
  • [Patent] 生体材料保存組成物,生体材料の保存方法,生体材料の生産方法,移植材料,および移植方法2018

    • Inventor(s)
      畑山直之, 内藤宗和, 平井宗一, 坂上茂樹.
    • Industrial Property Rights Holder
      畑山直之, 内藤宗和, 平井宗一, 坂上茂樹.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-16K09219
  • [Presentation] ウルトラファインバブルの医療応用に向けた検討2024

    • Author(s)
      内藤宗和 福重香 竹内堂朗 畑山直之
    • Organizer
      解剖学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K25234
  • [Presentation] ウルトラファインバブル製剤の実用化に向けた検討 -NOガス降圧剤-2023

    • Author(s)
      福重 香, 畑山 直之, 竹内 堂朗, 内藤 宗和
    • Organizer
      日本薬学会 第143年会
    • Data Source
      KAKENHI-PROJECT-22K08706
  • [Presentation] Effective partial pressure for rat heart preservation in a high-pressure gaseous mixture of carbon monoxide and oxygen2020

    • Author(s)
      畑山 直之
    • Organizer
      第125回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-19K09108
  • [Presentation] Effective partial pressure for rat heat preservation in a high-pressure gaseous mixture of carbon monoxide and oxygen2020

    • Author(s)
      Hatayama N, Hirai S, Fukushige K, Yokota H, Nakano T, Naito N
    • Organizer
      第125回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17H04274
  • [Presentation] 医療応用を目指したウルトラファインバブル(UFB)の有効性評価 -酸素および空気UFBが培養細胞の生存に与える効果と影響-2019

    • Author(s)
      福重香,平井宗一,畑山直之,横田紘季,中野隆,内藤宗和
    • Organizer
      第124回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17H04274
  • [Presentation] The hemoglobin affinity of carbon monoxide in the ultra-fine bubble.2019

    • Author(s)
      Shuichi Hirai, Naoyuki Hatayama, Kaori Fukushige, Hiroki Yokota, Tomiko Yakura, Atsushi Fujiwara, Masaya Yasui, Chiharu Suzuki, Munekazu Naito, Takashi Nakano
    • Organizer
      第124回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17H04274
  • [Presentation] 高圧ガスを用いた新たな移植臓器の保存方法.2018

    • Author(s)
      畑山直之, 平井宗一, 横田紘季, 矢倉富子, 福重香, 中野隆, 内藤宗和.
    • Organizer
      第123回日本解剖学会総会・全国学術集会.2018.
    • Data Source
      KAKENHI-PROJECT-16K09219
  • [Presentation] 閉塞性睡眠時無呼吸症候群病態解析のための無意識下間歇的気道閉塞モデルの確立2018

    • Author(s)
      加藤佑哲,梅本佳納榮,大矢祐輔,畑山直之,平井宗一,内藤宗和,中野隆
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-16K09219
  • [Presentation] 高圧ガスを用いた新たな移植臓器の保存方法2018

    • Author(s)
      畑山直之,平井宗一,横田紘季,矢倉富子,福重香,中野隆,内藤宗和
    • Organizer
      第123回日本解剖学会総会・全国学術集会
    • Data Source
      KAKENHI-PROJECT-17H04274
  • [Presentation] 閉塞性睡眠時無呼吸症候群病態解析のための無意識下間歇的気道閉塞モデルの確立.2018

    • Author(s)
      加藤佑啓, 梅本佳納榮, 大矢祐輔, 畑山直之, 平井宗一, 内藤宗和, 中野隆.
    • Organizer
      123回日本解剖学会総会・全国学術集会.2018.
    • Data Source
      KAKENHI-PROJECT-16K09219
  • [Presentation] 高圧ガスを用いた新たな移植臓器の保存方法2018

    • Author(s)
      畑山直之,平井宗一,横田紘季,矢倉富子,福重香,中野隆,内藤宗和
    • Organizer
      第123回 日本解剖学会総会
    • Data Source
      KAKENHI-PROJECT-15K10151
  • [Presentation] 高圧ガスを用いた臓器保存の試み2017

    • Author(s)
      畑山直之、平井宗一、横田紘季、矢倉富子、福重香、内藤宗和
    • Organizer
      第53回 日本移植学会総会
    • Data Source
      KAKENHI-PROJECT-15K10151
  • [Presentation] Cervical heterotopic testis transplantation in rats2016

    • Author(s)
      易 凱,畑山直之, 平井宗一, 曲 寧, 林 省吾, 伊藤正裕.
    • Organizer
      第177回東京医科大学医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2016-06-04
    • Data Source
      KAKENHI-PROJECT-15K08159
  • [Presentation] Saturated salt solution (SSS) 法を用いたサージカルトレーニング:形成外科学, 脳外科学領域への拡張2016

    • Author(s)
      林省吾、河田晋一、白井隆之、曲寧、畑山直之、平井宗一、伊藤正裕
    • Organizer
      第121回日本解剖学会総会・全国学術集会
    • Place of Presentation
      ビッグパレットふくしま
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-26670254
  • [Presentation] SSS法と尿素法による解剖体ホルムアルデヒド濃度低減効果2016

    • Author(s)
      河田晋一、小山耕一、林省吾、平井宗一、曲寧、畑山直之、 中村陽市、伊藤正裕
    • Organizer
      第121回日本解剖学会総会・全国学術集会
    • Place of Presentation
      ビッグパレットふくしま
    • Year and Date
      2016-03-28
    • Data Source
      KAKENHI-PROJECT-26670254
  • [Presentation] 高圧気相保存法による移植臓器の保存2016

    • Author(s)
      畑山直之, 平井宗一, 内藤宗和, 伊藤正裕, 中野 隆
    • Organizer
      日本解剖学会第76回中部支部学術集会
    • Place of Presentation
      長野
    • Year and Date
      2016-11-08
    • Data Source
      KAKENHI-PROJECT-15K08159
  • [Presentation] ラットにおける異所性精巣移植の試み2016

    • Author(s)
      畑山直之,曲 寧,林 省吾,平井宗一,倉升三幸,永堀健太,小川夕輝,高橋薫平,伊藤正裕
    • Organizer
      第121回日本解剖学会総会・学術集会
    • Place of Presentation
      福島県(郡山)
    • Year and Date
      2016-03-28
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K08159
  • [Presentation] ラットにおける異所性精巣移植の試み2015

    • Author(s)
      畑山直之,曲 寧,林 省吾,平井宗一,倉升三幸,永堀健太,小川夕輝,高橋薫平,伊藤正裕
    • Organizer
      第30回日本生殖免疫学会・学術集会
    • Place of Presentation
      熊本県(熊本)
    • Year and Date
      2015-11-21
    • Data Source
      KAKENHI-PROJECT-15K08159
  • [Presentation] 高圧気相保存法による臓器保存2015

    • Author(s)
      畑山直之
    • Organizer
      日本臓器保存生物医学会
    • Place of Presentation
      岩手県
    • Year and Date
      2015-11-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-25861709
  • [Presentation] 高圧気相保存法による臓器保存2015

    • Author(s)
      畑山直之
    • Organizer
      日本臓器保存生物医学会
    • Place of Presentation
      岩手県
    • Year and Date
      2015-11-13
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K10151
  • [Presentation] 微量カドミウム曝露は自己免疫障害を増悪させる2014

    • Author(s)
      小川夕輝, 倉升三幸, 曲  寧, 平井宗一, 林 省吾, 畑山直之, 伊藤正裕
    • Organizer
      第29回日本生殖免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-12-13
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] Successful long-term preservation of rat limbs by a combination of high-pressure carbon monoxide and oxygen for replantation2014

    • Author(s)
      畑山直之
    • Organizer
      第119回日本解剖学会全国学術集会
    • Place of Presentation
      栃木:自治医科大学
    • Data Source
      KAKENHI-PROJECT-25861709
  • [Presentation] 精巣とサイトカイン2013

    • Author(s)
      寺山 隼人, 内藤 宗和, 曲 寧, 平井 宗一, 畑山 直之, 伊藤 正裕
    • Organizer
      第118回日本解剖学会総会・学術集会
    • Place of Presentation
      香川
    • Invited
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] 移植用臓器における高圧保存法の可能性2013

    • Author(s)
      畑山 直之
    • Organizer
      118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] Testicular immune-microenvironment in the Epstein-Barr virus-induced gene-3 (EBI3) knock out mice.2013

    • Author(s)
      Terayama H, Hirai S, Yoshimoto T, Naito M, Qu N, Hatayama N, Sakabe K*, Itoh M.
    • Organizer
      12th International Congress of Reproductive Immunology
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] 移植用臓器における高圧保存法の可能性2013

    • Author(s)
      畑山直之
    • Organizer
      第118回日本解剖学会総会・全国学術集会
    • Place of Presentation
      香川県高松市
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] 微量カドミウム曝露は自己免疫性精子形成障害を増悪させる2013

    • Author(s)
      小川夕輝, 倉升三幸, 曲 寧, 平井宗一, 林 省吾, 畑山直之, 内藤宗和, 伊藤正裕
    • Organizer
      第20回日本免疫毒性学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] CO2とO2およびCOとO2の混合ガスを用いた高圧気相保存法2013

    • Author(s)
      畑山直之
    • Organizer
      第40回日本臓器保存生物医学会学術集会
    • Place of Presentation
      東京:東京医科大学
    • Data Source
      KAKENHI-PROJECT-25861709
  • [Presentation] 低用量フタル酸曝露による自己免疫性精巣炎誘導への影響2013

    • Author(s)
      内藤宗和, 平井宗一, 曲 寧, 倉升三幸, 小川夕輝, 畑山直之, 林 省吾, 伊藤正裕
    • Organizer
      第28回日本生殖免疫学会総会・学術集会
    • Place of Presentation
      兵庫
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] 免疫正常マウスにおけるブスルファンの免疫系と生殖系への影響2013

    • Author(s)
      平柳淑恵, 曲 寧, 平井宗一, 内藤宗和, 倉升三幸, 林 省吾, 畑山直之, 伊藤正裕
    • Organizer
      第20回日本免疫毒性学会学術大会
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] Role of macrophages in newly formed lymphatic vessels in the testis.2013

    • Author(s)
      Hirai S, Naito M, Terayama H, Qu N, Hatayama N, Musha M, Itoh M.
    • Organizer
      12th International Congress of Reproductive Immunology
    • Place of Presentation
      Boston, USA
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] 臓器保存におけるメディカルガスの可能性:一酸化炭素(CO)と酸素(O2)を用いた高圧保存法2012

    • Author(s)
      畑山直之
    • Organizer
      第39回日本臓器保存生物学会学術集会
    • Place of Presentation
      福島県福島市
    • Invited
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] 臓器保存におけるメディカルガスの可能性~一酸化炭素(CO)と酸素(O2)を用いた高圧保存法~2012

    • Author(s)
      畑山 直之
    • Organizer
      第39回日本臓器保存生物医学会学術集会
    • Place of Presentation
      福島
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] CO と O2 を用いた高圧保存法におけるラット心臓の機能的評価2011

    • Author(s)
      畑山 直之
    • Organizer
      第167回東京医科大学医学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] COとO2混合ガスを用いた高圧保存法におけるラット心臓の機能的評価2011

    • Author(s)
      畑山直之
    • Organizer
      東京医科大学医学会総会
    • Place of Presentation
      東京医科大学病院
    • Year and Date
      2011-06-04
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] ラット摘出心臓によるCOを用いた高圧乾燥保存法の保存限界とメカニズム2010

    • Author(s)
      畑山直之
    • Organizer
      第37回日本臓器保存生物医学会学術集会
    • Place of Presentation
      新潟県新潟市
    • Data Source
      KAKENHI-PROJECT-22390239
  • [Presentation] ラット摘出心臓による COを用いた高圧乾燥保存法の保存限界とメカニズム2010

    • Author(s)
      畑山 直之
    • Organizer
      第37回日本臓器保存生物医学会学術集会
    • Place of Presentation
      新潟
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] [18F]FDG-PET studies of heterotopic heart transplantation in rats2010

    • Author(s)
      Inubushi M, Hatayama N, Li XK, Jin YN, Koizumi M, Saga T
    • Organizer
      10th Congress of the World Federation of Nuclear Medicine and Biology
    • Place of Presentation
      Cape Town, Republic of South Africa
    • Data Source
      KAKENHI-PROJECT-22390239
  • [Presentation] ラット摘出心臓によるCOを用いた高圧乾燥保存法の保存限界とメカニズム2010

    • Author(s)
      畑山直之
    • Organizer
      第37回日本臓器保存生物医学会学術集会
    • Place of Presentation
      新潟県新潟市
    • Data Source
      KAKENHI-PROJECT-22791266
  • [Presentation] ブスルファン処置マウスの精子形成障害における牛車腎気丸の治療効果

    • Author(s)
      曲  寧, 平栁淑恵, 林 省吾, 平井宗一, 畑山直之, 倉升三幸, 小川夕輝, 伊藤正裕
    • Organizer
      第29回日本生殖免疫学会総会・学術集会
    • Place of Presentation
      東京
    • Year and Date
      2014-12-12 – 2014-12-13
    • Data Source
      KAKENHI-PROJECT-23500504
  • [Presentation] 2.Saturated salt solution法固定遺体のサージカル・トレーニングへの有用性:外科医の評価と手技施行の可能性

    • Author(s)
      林 省吾, 河田晋一, 曲 寧, 畑山直之, 内藤宗和, 平井宗一, 伊藤正裕
    • Organizer
      第120回日本解剖学会総会・全国学術集会
    • Place of Presentation
      神戸国際会議場・展示場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-26670254
  • [Presentation] Functional evaluation of rat heart transplanted after preservation in a high-pressure carbon monoxide and oxygen mixed gas

    • Author(s)
      Naoyuki Hatayama
    • Organizer
      World Transplant Congress 2014 San Francisco
    • Place of Presentation
      San Francisco, CA, United States
    • Year and Date
      2014-07-26 – 2014-07-31
    • Data Source
      KAKENHI-PROJECT-25861709
  • [Presentation] サージカルトレーニングから見た各種固定法の比較:防腐効果と硬化について

    • Author(s)
      河田晋一, 小山耕一, 林 省吾, 曲 寧, 畑山直之, 中村陽市, 藤倉義久, 伊藤正裕
    • Organizer
      第120回日本解剖学会総会・全国学術集会
    • Place of Presentation
      神戸国際会議場・展示場
    • Year and Date
      2015-03-21 – 2015-03-23
    • Data Source
      KAKENHI-PROJECT-26670254
  • [Presentation] 1.Cadavers embalmed by the saturated salt solution method are useful for surgical skills training

    • Author(s)
      Hayashi S, Naito M, Kawata S, Qu N, Hatayama N, Hirai S, Itoh M
    • Organizer
      第2回アジア臨床解剖学会/第18回臨床解剖研究会
    • Place of Presentation
      東京医科歯科大学
    • Year and Date
      2014-11-08 – 2014-11-09
    • Data Source
      KAKENHI-PROJECT-26670254
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    # of Collaborated Projects: 11 results
    # of Collaborated Products: 26 results
  • 2.  HIRAI Shuichi (70516054)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 35 results
  • 3.  ITOH Masahiro (00232471)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 26 results
  • 4.  福重 香 (30805023)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 3 results
  • 5.  LI Xiao-kang (60321890)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 2 results
  • 6.  HAYASHI Shogo (60349496)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 18 results
  • 7.  横田 紘季 (50815876)
    # of Collaborated Projects: 5 results
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  • 8.  QU Ning (70527952)
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    # of Collaborated Products: 22 results
  • 9.  Kawata Shinichi (00527955)
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  • 10.  伊藤 恭彦 (60402632)
    # of Collaborated Projects: 3 results
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  • 11.  INUBUSHI Masayuki (70399830)
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    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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    # of Collaborated Projects: 1 results
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