Nabekura Tsukasa 鍋倉宰

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NABEKURA Tsukasa 鍋倉宰

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Researcher Number	80550095
Other IDs
Affiliation (Current)	2025: 愛知県がんセンター(研究所), 腫瘍免疫応答研究分野, 分野長
Affiliation (based on the past Project Information) *help	2025: 愛知県がんセンター(研究所), 腫瘍免疫応答研究分野, 分野長 2018 – 2019: 筑波大学, 生存ダイナミクス研究センター, 助教 2017: 筑波大学, 生命領域学際研究センター, 助教 2009 – 2010: University of Tsukuba, 大学院・人間総合科学研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Immunology / Hematology
Keywords	Principal Investigator 記憶NK細胞 / ナチュラルキラー細胞 / がん免疫療法 / Themis2 / キメラ抗原受容体 / サイトメガロウイルス / 記憶細胞分化 / NK細胞 / ウイルス感染 / 免疫記憶 … More / 免疫学 / 骨髄移植 / 抗体療法 / DNAM-1 / GVHD / 移植片対宿主病 Less

Development of next-generation of CAR NK cells targeting memory cell differentiation and a regulatory factor for cancer immunityPrincipal Investigator
- Principal Investigator
  
  鍋倉宰
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Aichi Cancer Center Research Institute
Identification of a master regulator of the differentiation of memory natural killer cellsPrincipal Investigator
- Principal Investigator
  
  Nabekura Tsukasa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Immunology
- Research Institution
  University of Tsukuba
Involvement of DNAM-1 in the development of graft-versus-host diseasePrincipal Investigator
- Principal Investigator
  
  NABEKURA Tsukasa
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Hematology
- Research Institution
  University of Tsukuba

All 2020 2019 2018 2017 2011 2010 2009

All Journal Article Presentation

[Journal Article] Type 1 innate lymphoid cells protect mice from acute liver injury via interferon-g secretion for upregulating Bcl-xL expression in hepatocytes2020
- Author(s)
  Nabekura T, Riggan L, Hildreth AD, O'Sullivan TE, Shibuya A
- Journal Title
  
  Immunity
  
  Volume: 52(1) Issue: 1 Pages: 96-108
- DOI
  10.1016/j.immuni.2019.11.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05022, KAKENHI-PROJECT-16H06387, KAKENHI-PROJECT-17H05071
[Journal Article] The cis-Regulatory Atlas of the Mouse Immune System2019
- Author(s)
  Yoshida H, Lareau CA, Ramirez RN, Rose SA, Maier B, Wroblewska A, Desland F, Chudnovskiy A, Mortha A, Dominguez C, Tellier J, Kim E, Dwyer D, Shinton S, Nabekura T, Qi Y, Yu B, Robinette M, Kim KW, Wagers A, Rhoads A, Nutt SL, Brown BD, Mostafavi S, Buenrostro JD, Benoist C; Immunological Genome Project.
- Journal Title
  
  Cell
  
  Volume: 176 Issue: 4 Pages: 897-912.e20
- DOI
  10.1016/j.cell.2018.12.036
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05071
[Journal Article] Crk adaptor proteins regulate NK cell expansion and differentiation during mouse cytomegalovirus infection2018
- Author(s)
  Tsukasa Nabekura, Zhiying Chen, Casey Schroeder, Taeju Park, Eric Vivier, Lewis L. Lanier, and Dongfang Liu
- Journal Title
  
  J Immunol
  
  Volume: in press Issue: 10 Pages: 3691-3696
- DOI
  10.4049/jimmunol.1701639
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05071, KAKENHI-PUBLICLY-18H05022, KAKENHI-PROJECT-16H06387
[Journal Article] Cutting Edge: NKG2D signaling enhances Ly49H+ natural killer cell responses but alone is insufficient to drive expansion during mouse cytomegalovirus infection2017
- Author(s)
  Tsukasa Nabekura, Dagmar Gotthardt, Kouta Niizuma, Tihana Trsan, Tina Jenus, Stipan Jonjic, and Lewis L. Lanier
- Journal Title
  
  J Immunol
  
  Volume: 199 Issue: 5 Pages: 1567-1571
- DOI
  10.4049/jimmunol.1700799
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05071, KAKENHI-PROJECT-15J08253
[Journal Article] Reply to Seth et al. : DNAX accessory molecule-1 (DNAM-1) plays an important role in alloreactive CD8+ T cells responsible for the exacerbation of acute graft-versus-host disease2011
- Author(s)
  Tsukasa Nabekura, Kazuko Shibuya, Akira Shibuya
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: Vol.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890026
[Journal Article] DNAX accessory molecule-1 (DNAM-1) plays an important role in alloreactive CD8+ T cells responsible for the exacerbation of acute graft-versus-host disease2011
- Author(s)
  Tsukasa Nabekura, Kazuko Shibuya, Akira Shibuya、Reply to Seth, et al.
- Journal Title
  
  Proc Natl Acad Sci USA 108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890026
[Journal Article] A critical role of DNAM-1 in the development of acute graft-versus-host disease in mice2010
- Author(s)
  Tsukasa Nabekura, Kazuko Shibuya, Eri Takenaka, Hirayasu Kai, Kai Shibata, Yumi Yamashita, Kyoichi Harada, Satoko Tahara-Hanaoka, Shin-ichiro Honda, Akira Shibuya
- Journal Title
  
  Proc Natl Acad Sci USA 107
  
  Pages: 18593-18598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890026
[Journal Article] A critical role of DNAM-1 in the development of acute graft-versus-host disease in mice2010
- Author(s)
  Tsukasa Nabekura, Kazuko Shibuya、, Eri Takenaka, Hirayasu Kai, Kai Shibata, Yumi Yamashita, Kyoichi Harada, Satoko Tahara-Hanaoka, Shin-ichiro Honda, Akira Shibuya
- Journal Title
  
  Proc Natl Acad Sci USA
  
  Volume: Vol.107 Pages: 18593-18598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] Protective role of type 1 innate lymphoid cells in acute liver injury2019
- Author(s)
  Tsukasa Nabekura
- Organizer
  The 48th Annual Meeting of the Japanese Society of Immunology
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] Tracking the Fate of Antigen-specific Versus Cytokine-activated Natural Killer Cells after Cytomegalovirus Infection2018
- Author(s)
  Tsukasa Nabekura
- Organizer
  The 3rd International Conference of Innate Lymphoid Cells
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection2018
- Author(s)
  Tsukasa Nabekura
- Organizer
  RIKEN Center for Integrative Medical Sciences (IMS)-Japanese Society of Immunology (JSI) International Symposium on Immunology 2018
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] NKG2D signaling enhances Ly49H+ natural killer cell responses but alone is insufficient to drive expansion during mouse cytomegalovirus infection2017
- Author(s)
  Tsukasa Nabekura
- Organizer
  The 6th Retreat of University of Tsukuba and Tokyo University of Science
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] Activating receptors for self-MHC class I enhance effector functions and memory differentiation of NK cells during mouse cytomegalovirus infection2017
- Author(s)
  Tsukasa Nabekura
- Organizer
  The 9th Annual Meeting of Society of Immunotherapy for Hematological Disorders
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection2017
- Author(s)
  Tsukasa Nabekura
- Organizer
  The 9th Annual Meeting of Society of Immunotherapy for Hematological Disorders
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection2017
- Author(s)
  Tsukasa Nabekura
- Organizer
  The 46th Annual Meeting of the Japanese Society of Immunology
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] Activating receptors for self-MHC class I enhance effector functions and memory differentiation of NK cells during mouse cytomegalovirus infection2017
- Author(s)
  Tsukasa Nabekura
- Organizer
  The 26th Molecular Immunology Forum Tokyo
- Invited
- Data Source
  KAKENHI-PROJECT-17H05071
[Presentation] A critical role of DNAM-1 in the development of acute graft-versus-host disease2011
- Author(s)
  鍋倉宰
- Organizer
  第5回つくば医科学研究交流会
- Place of Presentation
  筑波大学(茨城県)
- Year and Date
  2011-01-22
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] DNAM-1は移植片対宿主病の発症において重要な役割を果たす2010
- Author(s)
  鍋倉宰
- Organizer
  第20回京都T細胞カンファレンス
- Place of Presentation
  京都大学(京都府)
- Year and Date
  2010-06-05
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] A critical role of DNAM-1 in the development of acute graft-versus-host disease2010
- Author(s)
  鍋倉宰
- Organizer
  Keystone Symposia on Molecular and Cellular Biology(Lymphocyte Activation)
- Place of Presentation
  Beaver Run Resort、Breckenridge、コロラド州、米国
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] A critical role of DNAM-1 in the development of acute graft-versus-host disease2010
- Author(s)
  鍋倉宰
- Organizer
  第2回造血器腫瘍免疫療法研究会
- Place of Presentation
  大和屋本店(愛媛県)
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] A critical role of DNAM-1 in the development of acute graft-versus-host disease2010
- Author(s)
  鍋倉宰
- Organizer
  The 14th International Congress of Immunology
- Place of Presentation
  神戸国際会議場(兵庫県)
- Year and Date
  2010-08-26
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] 抗DNAM-1モノクローナル抗体を用いた移植片対宿主病に対する新規予防および治療法の開発2010
- Author(s)
  鍋倉宰
- Organizer
  第2回造血器腫瘍免疫療法研究会
- Place of Presentation
  大和屋本店(愛媛県)
- Year and Date
  2010-08-28
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] A critical role of DNAM-1 in the development of acute graft-versus-host disease2010
- Author(s)
  鍋倉宰
- Organizer
  The Keystone Symposia on Molecular and Cellular Biology
- Place of Presentation
  Beaver Run Resort(コロラド州、米国)
- Year and Date
  2010-03-01
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] Novel prophylactic and therapeutic approaches to GVHD with a monoclonal antibody against DNAM-12009
- Author(s)
  鍋倉宰
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都国際会館
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] 抗DNAM-1モノクローナル抗体を用いた移植片対宿主病に対する新規予防および治療法の開発2009
- Author(s)
  鍋倉宰
- Organizer
  第71回日本血液学会
- Place of Presentation
  京都国際会館(京都府)
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] Novel prophylactic and therapeutic approaches to GVHD with a monoclonal antibody against DNAM-12009
- Author(s)
  鍋倉宰
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21890026
[Presentation] 抗DNAM-1モノクローナル抗体を用いた移植片対宿主病に対する新規予防および治療法の開発2009
- Author(s)
  鍋倉宰
- Organizer
  第39回日本免疫学会
- Place of Presentation
  大阪国際会議場(大阪府)
- Year and Date
  2009-12-03
- Data Source
  KAKENHI-PROJECT-21890026

1. 渋谷彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nabekura Tsukasa 鍋倉 宰

NABEKURA Tsukasa 鍋倉 宰

Research Projects

Research Products

Co-Researchers

Development of next-generation of CAR NK cells targeting memory cell differentiation and a regulatory factor for cancer immunityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of a master regulator of the differentiation of memory natural killer cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of DNAM-1 in the development of graft-versus-host diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Type 1 innate lymphoid cells protect mice from acute liver injury via interferon-g secretion for upregulating Bcl-xL expression in hepatocytes2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The cis-Regulatory Atlas of the Mouse Immune System2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crk adaptor proteins regulate NK cell expansion and differentiation during mouse cytomegalovirus infection2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cutting Edge: NKG2D signaling enhances Ly49H+ natural killer cell responses but alone is insufficient to drive expansion during mouse cytomegalovirus infection2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Reply to Seth et al. : DNAX accessory molecule-1 (DNAM-1) plays an important role in alloreactive CD8+ T cells responsible for the exacerbation of acute graft-versus-host disease2011

Author(s)

Journal Title

Data Source

[Journal Article] DNAX accessory molecule-1 (DNAM-1) plays an important role in alloreactive CD8+ T cells responsible for the exacerbation of acute graft-versus-host disease2011

Author(s)

Journal Title

Data Source

[Journal Article] A critical role of DNAM-1 in the development of acute graft-versus-host disease in mice2010

Author(s)

Journal Title

Data Source

[Journal Article] A critical role of DNAM-1 in the development of acute graft-versus-host disease in mice2010

Author(s)

Journal Title

Data Source

[Presentation] Protective role of type 1 innate lymphoid cells in acute liver injury2019

Author(s)

Organizer

Data Source

[Presentation] Tracking the Fate of Antigen-specific Versus Cytokine-activated Natural Killer Cells after Cytomegalovirus Infection2018

Author(s)

Organizer

Data Source

[Presentation] Tracking the fate of antigen-specific versus cytokine-activated natural killer cells after cytomegalovirus infection2018

Author(s)

Organizer

Data Source

[Presentation] NKG2D signaling enhances Ly49H+ natural killer cell responses but alone is insufficient to drive expansion during mouse cytomegalovirus infection2017

Author(s)

Organizer

Data Source

[Presentation] Activating receptors for self-MHC class I enhance effector functions and memory differentiation of NK cells during mouse cytomegalovirus infection2017

Author(s)

Organizer

Data Source

[Presentation] Costimulatory molecule DNAM-1 is essential for optimal differentiation of memory natural killer cells during mouse cytomegalovirus infection2017

Nabekura Tsukasa 鍋倉宰

NABEKURA Tsukasa 鍋倉宰