Yagi Kenji 八木謙次

… Alternative Names

YAGI KENJI 八木謙次

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Researcher Number	80551837
Other IDs
Affiliation (based on the past Project Information) *help	2018 – 2022: 川崎医科大学, 医学部, 講師 2017: 徳島大学, 大学病院, 講師 2016 – 2017: 福岡大学, 医学部, 講師 2015: 徳島大学, 大学病院, 講師 2009 – 2011: 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 2009: 徳島大学, 大学院・ヘルバイオサイエンス研究部, 助教
Review Section/Research Field	Principal Investigator Neurosurgery Except Principal Investigator Neurosurgery / Cerebral neurosurgery / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator 炎症性ｻｲﾄｶｲﾝ / Ｍ１/Ｍ２マクロファージ / 神経再生 / phagocytosis / 炎症性サイトカイン / Ｍ１/Ｍ２様マクロファージ / 脳梗塞 / 脳・神経 Except Principal Investigator 脳動脈瘤 / エストロゲン … More / 脳動脈瘤破裂 / 歯周病 / 高血圧 / 炎症 / sirtuin / 歯周病菌 / くも膜下出血 / 脳血管病 / 脳・神経 / angiotensin II / 血管内皮障害 / phosphodiesterase / mineral corticoid receptor / タイトジャンクション蛋白 / NLRP3 inflammasome / Sirtuin / NLRP3　inflammasome / ERa / NLRP3 / Inflammasome / 破裂性脳血管病 / ERα / exosome / periodontal bacteria / periodontal disease / intracranial aneurysms / SAH / 頚動脈病変 / 血管障害 / 脳 / 脳動脈瘤破裂　血行動態変化 / 血行動態変化 / エストロゲン受容体調整薬 / 酸化ストレス / タイトジャンクショク蛋白 / マクロファージ / ZO-1 / cccludin / ラット Less

Effects of exosomes of periodontal lesions on ruptured cerebral aneurysms
- Principal Investigator
  
  SHIMADA Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokushima
Role of inflammasome activation and sirtuins in cerebral aneurysm rupture
- Principal Investigator
  
  KANEMATSU Yasuhisa
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  The University of Tokushima
脳梗塞後PPARγ賦活による脳保護作用と神経再生
- Principal Investigator
  
  木内智也
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  The University of Tokushima
Intracranial aneurysms related to periodontal disease in basic- and clinical studies
- Principal Investigator
  
  KANEMATSU Yasuhisa
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  The University of Tokushima
Activation of M2-type macrophages in the late phase of cerebral ischemia promotes neurogenesis with cleaning of the infarct area.Principal Investigator
- Principal Investigator
  
  Yagi Kenji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Fukuoka University
  The University of Tokushima
Early diagnosis and pharmacological treatment to prevent the rupture of cerebral aneurysms
- Principal Investigator
  
  NAGAHIRO Shinji
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  The University of Tokushima
molecular mechanisms in the formation and rupture of cerebral aneurysm and impact of drug treatment
- Principal Investigator
  
  NAGAHIRO Shinji
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokushima
Bidirectional effects of statins on the formation and growth of cerebral aneurysms
- Principal Investigator
  
  SATOMI Junichiro
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokushima
Reductionof endothelial tight junction proteins on experimental cerebral aneurysm in rats
- Principal Investigator
  
  NISHI Kyoko, 中嶌教夫
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  The University of Tokushima

All 2023 2022 2020 2019 2018 2017 2016 2015 2012 2011 2010 2009 2008

All Journal Article Presentation

[Journal Article] Activation of the NLRP3/IL-1β/MMP-9 pathway and intracranial aneurysm rupture associated with the depletion of ERα and Sirt1 in oophorectomized rats2023
- Author(s)
  Yamaguchi Tadashi、Miyamoto Takeshi、Shikata Eiji、Yamaguchi Izumi、Shimada Kenji、Yagi Kenji、Tada Yoshiteru、Korai Masaaki、Kitazato Keiko T.、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: 138 Issue: 1 Pages: 191-198
- DOI
  10.3171/2022.4.jns212945
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-20K09391, KAKENHI-PROJECT-20K17933
[Journal Article] Role of post-ischemic phase-dependent modulation of anti-inflammatory M2-type macrophages against rat brain damage2022
- Author(s)
  Kurashiki Yoshitaka、Kagusa Hiroshi、Yagi Kenji、Kinouchi Tomoya、Sumiyoshi Manabu、Miyamoto Takeshi、Shimada Kenji、Kitazato Keiko T、Uto Yoshihiro、Takagi Yasushi
- Journal Title
  
  Journal of Cerebral Blood Flow & Metabolism
  
  Volume: 43 Issue: 4 Pages: 531-541
- DOI
  10.1177/0271678x221147090
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09326
[Journal Article] An imbalance between RAGE/MR/HMGB1 and ATP1α3 is associated with inflammatory changes in rat brain harboring cerebral aneurysms prone to rupture2022
- Author(s)
  Shikata Eiji、Miyamoto Takeshi、Yamaguchi Tadashi、Yamaguchi Izumi、Kagusa Hiroshi、Gotoh Daiki、Shimada Kenji、Tada Yoshiteru、Yagi Kenji、Kitazato Keiko T.、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 19 Issue: 1
- DOI
  10.1186/s12974-022-02526-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09259, KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-20K09391
[Journal Article] Disequilibrium of plasma protease/anti-protease due to severe periodontal disease contributes to human subarachnoid hemorrhage2020
- Author(s)
  Yoshioka S, Miyamoto T, Satomi J, Tada Y, Yagi K, Shimada K, Naruishi K, Shikata E, Yamaguchi I, Yamaguchi1 T, Korai M, Okayama Y, Harada M, Kitazato K, Kanematsu Y, Nagahiro S, Takagi Y
- Journal Title
  
  Neurosurgery Open
  
  Volume: 1 Issue: 3 Pages: 1-9
- DOI
  10.1093/neuopn/okaa007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10131, KAKENHI-PROJECT-20K09326, KAKENHI-PROJECT-19K24013
[Journal Article] Time-dependent and site-dependent morphological changes in rupture-prone arteries: ovariectomized rat intracranial aneurysm model2019
- Author(s)
  Yamaguchi Tadashi、Miyamoto Takeshi、Kitazato Keiko T.、Shikata Eiji、Yamaguchi Izumi、Korai Masaaki、Shimada Kenji、Yagi Kenji、Tada Yoshiteru、Matsuzaki Yoshihito、Kanematsu Yasuhisa、Takagi Yasushi
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: - Issue: 5 Pages: 1-9
- DOI
  10.3171/2019.6.jns19777
- NAID
  120006880916
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16562, KAKENHI-PROJECT-17K10831, KAKENHI-PROJECT-17K10832
[Journal Article] Spot sign predicts rebleeding after endoscopic surgery for intracerebral hemorrhage2018
- Author(s)
  Miki K, Yagi K, Nonaka M,Iwaasa M, Abe H,Morishita T,Arima H,Inoue T
- Journal Title
  
  J Neurosurge
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10306
[Journal Article] Treatment of Unruptured Cerebral Aneurysms with the Mineralocorticoid Receptor Blocker Eplerenone-Pilot Study2018
- Author(s)
  1.Nagahiro S, Tada Y, Satomi J, Kinouchi T, Kuwayama K, Yagi K, Nakajima K, Matsushita N, Miyamoto T, Yamaguchi T, Shimada K, Korai M, Mure H, Okayama Y, Abe T, Harada M, Kitazato KT, Kanematsu Y
- Journal Title
  
  Stroke Cerebrovasc Dis
  
  Volume: - Issue: 8 Pages: 2134-2140
- DOI
  10.1016/j.jstrokecerebrovasdis.2018.03.008
- NAID
  120006961144
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10831, KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-17K10832, KAKENHI-PROJECT-18K16562
[Journal Article] Biofeedback effect of hybrid assistive limb in stroke rehabilitation: A proof of concept study using functional near infrared spectroscopy2018
- Author(s)
  Saita Kazuya、Morishita Takashi、Arima Hisatomi、Hyakutake Koichi、Ogata Toshiyasu、Yagi Kenji、Shiota Etsuji、Inoue Tooru
- Journal Title
  
  PLOS ONE
  
  Volume: 13 Issue: 1 Pages: e0191361-e0191361
- DOI
  10.1371/journal.pone.0191361
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-15K19984
[Journal Article] Endoscopic Surgery via a Combined Frontal and Suboccipital Approach for Cerebellar Hemorrhage2018
- Author(s)
  Nonaka M, Yagi1 K, Abe H, Miki K, Morishita T, Iwaasa M,Inoue T
- Journal Title
  
  Surg Neuro Int
  
  Volume: - Issue: 1 Pages: 68-68
- DOI
  10.4103/sni.sni_346_17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10306
[Journal Article] Intra-arterial high signals on arterial spin labeling perfusion images predict the occluded internal carotid artery segment2017
- Author(s)
  Sogabe S, Satomi J, Tada Y, Kanematsu Y, Kuwayama K, Yagi K, Yoshioka S, Mizobuchi Y, Mure H, Yamaguchi I, Abe T, Yamamoto N, Kitazato KT, Kaji R, Harada M, Nagahiro S
- Journal Title
  
  Neuroradiology.
  
  Volume: － Issue: 6 Pages: 587-595
- DOI
  10.1007/s00234-017-1828-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-26462159, KAKENHI-PROJECT-15K19972, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-16K10788, KAKENHI-PROJECT-17K10832, KAKENHI-PROJECT-15K10305
[Journal Article] Cerebral and spinal cavernomas associated with Klippel-Trenaunay syndrome: case report and literature review2017
- Author(s)
  Yoshinaga Takaya、Yagi Kenji、Morishita Takashi、Abe Hiroshi、Nonaka Masani、Inoue Tooru
- Journal Title
  
  Acta Neurochirurgica
  
  Volume: 160 Issue: 2 Pages: 287-290
- DOI
  10.1007/s00701-017-3408-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10306
[Journal Article] Cryptic recanalization of chronic vertebral artery occlusion by head rotation2017
- Author(s)
  Yagi K, Nakagawa H, Mure H, Okita S, Nagahiro S
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 26 Issue: 4 Pages: 60-61
- DOI
  10.1016/j.jstrokecerebrovasdis.2016.12.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-16K10788
[Journal Article] Treatment with the PPARγ Agonist Pioglitazone in the Early Post-ischemia Phase Inhibits Pro-inflammatory Responses and Promotes Neurogenesis Via the Activation of Innate- and Bone Marrow-Derived Stem Cells in Rats2017
- Author(s)
  Kinouchi Tomoya、Kitazato Keiko T.、Shimada Kenji、Yagi Kenji、Tada Yoshiteru、Matsushita Nobuhisa、Kurashiki Yoshitaka、Satomi Junichiro、Sata Masataka、Nagahiro Shinji
- Journal Title
  
  Transl Stroke Res
  
  Volume: - Issue: 3 Pages: 306-316
- DOI
  10.1007/s12975-017-0577-8
- NAID
  120007042447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-16H05299, KAKENHI-PROJECT-15K10306
[Journal Article] Bazedoxifene, a selective estrogen receptor modulator, reduces cerebral aneurysm rupture in Ovariectomized rats2017
- Author(s)
  Maekawa Hidetsugu、Tada Yoshiteru、Yagi Kenji、Miyamoto Takeshi、Kitazato Keiko T.、Korai Masaaki、Satomi Junichiro、Hashimoto Tomoki、Nagahiro Shinji
- Journal Title
  
  Journal of Neuroinflammation
  
  Volume: 14 Issue: 1 Pages: 197-204
- DOI
  10.1186/s12974-017-0966-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10831, KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-15K10306
[Journal Article] Coexistence of Quasi-moyamoya Disease and POEMS Syndrome in a Patient with Intracranial Hemorrhage: A Case Report and Literature Review2017
- Author(s)
  Yamaguchi I, Satomi J, Yamamoto N, Yoshioka S, Tada Y, Yagi K, Kanematsu Y, Nagahiro S
- Journal Title
  
  NMC Case Report Journal
  
  Volume: 4 Issue: 1 Pages: 5-9
- DOI
  10.2176/nmccrj.cr.2016-0106
- NAID
  130005239937
- ISSN
  2188-4226
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10306
[Journal Article] Site-specific elevation of interleukin-1β and matrix metalloproteinase-9 in the Willis circle by hemodynamic changes is associated with rupture in a novel rat cerebral aneurysm model2016
- Author(s)
  Miyamoto T, Kung DK, Kitazato KT, Yagi K, Shimada K, Tada Y, Korai M, Kurashiki Y, Kinouchi T, Kanematsu Y, Satomi J, Hashimoto T, Nagahiro S
- Journal Title
  
  J Cereb Blood Flow Metab
  
  Volume: － Issue: 8 Pages: 2795-2805
- DOI
  10.1177/0271678x16675369
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950, KAKENHI-PROJECT-26462159, KAKENHI-PROJECT-15K19972, KAKENHI-PROJECT-15K10305
[Journal Article] PPARγ-Dependent and -Independent Inhibition of the HMGB1/TLR9 Pathway by Eicosapentaenoic Acid Attenuates Ischemic Brain Damage in Ovariectomized Rats2015
- Author(s)
  Sumiyoshi M, Satomi J, Kitazato KT, Yagi K, Shimada K, Kurashiki Y, Korai M, Miyamoto T, Suzue R, Kuwayama K, Nagahiro S
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 24 Issue: 6 Pages: 1187-1195
- DOI
  10.1016/j.jstrokecerebrovasdis.2015.01.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10305, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-15H04950
[Journal Article] The accumulation of brain water-free sodium is associated with ischemic damage independent of the blood pressure in female rats2015
- Author(s)
  Sumiyoshi M, Kitazato KT, Yagi K, Miyamoto T, Kurashiki Y, Matsushita N, Kinouchi T, Kuwayama K, Satomi J, Nagahiro S
- Journal Title
  
  Brain Res
  
  Volume: 1616 Pages: 37-44
- DOI
  10.1016/j.brainres.2015.04.051
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10305, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-15H04950
[Journal Article] Therapeutically Targeting Tumor Necrosis Factor-α/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage2015
- Author(s)
  Yagi K, Lidington D, Wan H, Fares JC, Meissner A, Sumiyoshi M, Ai J1, Foltz WD, Nedospasov SA, Offermanns S, Nagahiro S, Macdonald RL, Bolz SS
- Journal Title
  
  Stroke
  
  Volume: 46 Issue: 8 Pages: 2260-2270
- DOI
  10.1161/strokeaha.114.006365
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-15H04950
[Journal Article] Intraoperative Arachnoid Plasty Has Possibility to Prevent Chronic Subdural Hematoma after Surgery for Unruptured Cerebral Aneurysms2015
- Author(s)
  Yagi K, Irie S, Inagaki T, Ishii Y, Saito O, Lee T, Nakagawa H, Saito K, Nagahiro S
- Journal Title
  
  Neurol. Med. Chir.(Tokyo)
  
  Volume: 55 Issue: 6 Pages: 493-497
- DOI
  10.2176/nmc.oa.2014-0455
- NAID
  130005076045
- ISSN
  0470-8105, 1349-8029
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-15H04950
[Journal Article] Improvement of Plasma Biomarkers after Switching Stroke Patients from Other Angiotensin II Type I Receptor Blockers to Olmesartan2015
- Author(s)
  Tada Y, Yagi K, Uno M, Matsushita N, Kanematsu Y, Kuwayama K, Shimada K, Nishi K, Hirasawa M, Satomi J, Kitazato KT, Kageji T, Matsuura E, Nagahiro S
- Journal Title
  
  J Stroke Cerebrovasc Dis
  
  Volume: 24 Issue: 7 Pages: 1487-1492
- DOI
  10.1016/j.jstrokecerebrovasdis.2015.03.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K10305, KAKENHI-PROJECT-15K10306, KAKENHI-PROJECT-26462159, KAKENHI-PROJECT-15K19972, KAKENHI-PROJECT-15H04950
[Journal Article] Nagahiro S Activation of signal transducer and activator of transcription-3 by a peroxisome proliferator-activated receptor gamma agonist contributes to neuroprotection in the peri-infarct region after ischemia in oophorectomized rats2012
- Author(s)
  Kinouchi T, Kitazato KT, Shimada K, Yagi K, Tada Y, Matsushita N, Sumiyoshi M, Satomi J, Kageji T
- Journal Title
  
  Stroke
  
  Volume: 43 Pages: 478-83
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591844
[Journal Article] Statins Promote the Growth of Experimentally-induced Cerebral Aneurysms in Estrogen-Deficient Rats2011
- Author(s)
  Tada Y, Kitazato KT, Yagi K, Shimada K, Matsushita N, Kinouchi T, Kanematsu Y, Satomi J, Kageji T, Nagahiro S
- Journal Title
  
  Stroke in press
- Data Source
  KAKENHI-PROJECT-20591686
[Journal Article] Activation of estrogen receptor-αand of angiotensin-converting enzyme 2 suppresses ischemic brain damage in oophorectomized rats2011
- Author(s)
  Shimada K, Kitazato KT, Kinouchi T, Yagi K, Tada Y, Satomi J, Kageji T, Nagahiro S
- Journal Title
  
  Hypertension
  
  Volume: 57 Issue: 6 Pages: 1161-6
- DOI
  10.1161/hypertensionaha.110.167650
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591844
[Journal Article] Statins promote the growth of experimentally induced cerebral aneurysms in estrogen-deficient rats2011
- Author(s)
  Tada Y, Kitazato KT, Yagi K, Shimada K, Matsushita N, Kinouchi T, Kanematsu Y, Satomi J, Kageji T, Nagahiro S
- Journal Title
  
  Stroke
  
  Volume: 42 Issue: 8 Pages: 2286-93
- DOI
  10.1161/strokeaha.110.608034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591844, KAKENHI-PROJECT-22791347
[Journal Article] Kruppel-like Zinc-Finger Transcription Factor 5(KLF5) Is Highly Expressed in Large and Giant Unruptured Cerebral Aneurysms2011
- Author(s)
  Nakajima N, Nagahiro S, Sano T, Satomi J, Tada Y, Yagi K, Kitazato KT, Satoh K
- Journal Title
  
  World Neurosurg
  
  Volume: Nov7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591844
[Journal Article] Reduction of endothelial tight junction proteins is related to cerebral aneurysm formation in rats2010
- Author(s)
  Tada Y, Yagi K, Kitazato KT, Tamura T, Kinouchi T, Shimada K, Matsushita N, Nakajima N, Satomi J, Kageji T, Nagahiro S
- Journal Title
  
  J Hypertens
  
  Volume: 28 Pages: 1883-91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591844
[Journal Article] Reduction of endothelial tight junction proteins is related to cerebral aneurysm formation in rats.2010
- Author(s)
  Tada Y, Yagi K, Kitazato KT, Tamura T, Kinouchi T, Shimada K, Matsushita N, Nakajima N, Satomi J, Kageji T, Nagahiro S.
- Journal Title
  
  J Hypertens. 28
  
  Pages: 1883-1891
- Data Source
  KAKENHI-PROJECT-20591686
[Journal Article] Ibudilast inhibits cerebral aneurysms by down-regulating inflammation-related molecules in the vascular wall of rats2010
- Author(s)
  Yagi K
- Journal Title
  
  Neurosurgery
  
  Volume: 66 Pages: 551-559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390412
[Journal Article] Ibudilast inhibits cerebral aneurysms by down-regulating inflammation-related molecules in the vascular wall of rats2010
- Author(s)
  Yagi K, Tada Y, Kitazato KT, Tamura T, Satomi J, Nagahiro S
- Journal Title
  
  Neurosurgery
  
  Volume: 66 Issue: 3 Pages: 551-9
- DOI
  10.1227/01.neu.0000365771.89576.77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591844
[Journal Article] Ibudilast inhibits cerebral aneurysms by down-regulating inflammation-related molecules in the vascular wall of rats.2010
- Author(s)
  Yagi K, Tada Y, Kitazato KT, Tamura T, Satomi J, Nagahiro S.
- Journal Title
  
  Neurosurgery. 66
  
  Pages: 551-559
- Data Source
  KAKENHI-PROJECT-20591686
[Journal Article] Endothelial damage due to impaired nitric oxide bioavailability triggers cerebral aneurysm formation in female rats2009
- Author(s)
  Tamura T, Jamous MA, Kitazato KT, Yagi K, Tada Y, Uno M, Nagahiro S
- Journal Title
  
  J Hypertens
  
  Volume: 27 Issue: 6 Pages: 1284-92
- DOI
  10.1097/hjh.0b013e328329d1a7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21591844
[Journal Article] Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats.2009
- Author(s)
  Tada Y, Kitazato KT, Tamura T, Yagi K, Shimada K, Kinouchi T, Satomi J, Nagahiro S.
- Journal Title
  
  Hypertension. 54
  
  Pages: 552-557
- Data Source
  KAKENHI-PROJECT-20591686
[Journal Article] Edaravone, a free radical scavenger, inhibits MMP-9-related brain hemorrhage in rats treated with tissue plasminogen activator2009
- Author(s)
  Yagi K
- Journal Title
  
  Stroke 4 0
  
  Pages: 626-631
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20591686
[Journal Article] Role of mineralocorticoid receptor on experimental cerebral aneurysms in rats2009
- Author(s)
  Tada Y, Kitazato KT, Tamura T, Yagi K, Shimada K, Kinouchi T, Satomi J, Nagahiro S
- Journal Title
  
  Hypertension
  
  Volume: 54 Pages: 552-7
- Data Source
  KAKENHI-PROJECT-21591844
[Journal Article] Endothelial damage due to impaired nitric oxide bioavailability triggers cerebral aneurysm formation in female rats.2009
- Author(s)
  Tamura T, Jamous MA, Kitazato KT, Yagi K, Tada Y, Uno M, Nagahiro S.
- Journal Title
  
  J Hypertens. 27
  
  Pages: 1284-12892
- Data Source
  KAKENHI-PROJECT-20591686
[Presentation] CEA後のkinking stenosisを危惧し、内径動脈のshortening procedure を施行した1例2018
- Author(s)
  小林広昌、湧田尚樹、森下登史、八木謙次、安部洋、野中将、東登志夫、井上亨
- Organizer
  第47回日本脳卒の外科学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] 脳卒中に対す内視鏡下血腫除去術後の再出血リスクファクターの検討2018
- Author(s)
  三木浩一、八木謙次、野中将、岩朝光利、安部洋、森下登史、有馬久富、井上亨
- Organizer
  第43回日本脳卒中学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] 脳卒中慢性期運動麻痺に対する系図外直流電気刺激療法を利用したリハビリテーション2018
- Author(s)
  森下登史、百武光一、斉田和哉、八木謙次、安部洋、井上亨
- Organizer
  第47回日本脳卒の外科学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] 小脳出血に対する神経内視鏡手術の複合戦略2018
- Author(s)
  野中将、天本宇昭、三木浩一、小林広昌、湧田尚樹、八木謙次、安部洋、岩朝光利、井上亨
- Organizer
  第47回日本脳卒の外科学会学術集会
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] 脳・脊髄に多発する症候性血管腫を呈したKlippel-Trenaunay syndromeの1例2017
- Author(s)
  八木謙次、吉永貴也、森下登史、安部洋、野中将、東登志夫、井上亨
- Organizer
  日本脳神経外科学会総会　第76回学術総会
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] 後大脳動脈瘤・上小脳動脈瘤に対する複合的治療の問題点2017
- Author(s)
  安部洋、松本徳彦、三木浩一、小林広昌、湧田尚樹、森下登史、八木謙次、野中将、岩朝光利、東登志夫、井上亨
- Organizer
  日本脳神経外科学会総会　第76回学術総会
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Pro-inflammatory Response Elicited by Porphyromonas Gingivalis Lipopolysaccharide Exacerbates the Rupture of Experimental Cerebral Aneurysms2017
- Author(s)
  Miyamoto T,Kitazato K、Tada Y、Shimada K、Yagi K、 Korai、Maekawa H、Yamaguchi T、 Yoshioka　S、 Kinouchi T、 Kanematsu Y、 Satomi J、Nagahiro S
- Organizer
  International Stroke Conference 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] A Pilot Study of the Mineralocorticoid Receptor Blocker Eplerenone in Hypertensive Patients with Unruptured Cerebral Aneurysms2016
- Author(s)
  J. Satomi, Y. Tada, Y. Kanematsu, K. Kuwayama, K. Yagi, T. Kinouchi, K. Nakajima, N. Matsushita, T. Miyamoto, T. Yamaguchi, M. Korai, H. Mure, K. T. Kitazato, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Impact of Periodontal Disease and －Bacteria on Intracranial Aneurysms2016
- Author(s)
  S. Yoshioka, Y. Tada, J. Satomi, K. Yagi, K. Naruishi, K. Kuwayama, K. T. Kitazato, T. Miyamoto, Y. Kanematsu, M. Harada, T. Nagata, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Activation of M2 macrophages in the late phase of cerebral ischema may contribute to phagocytosis of infract area and neurogenesis2016
- Author(s)
  Y. Kurashiki, K.T. Kitazato, K. Shimada, K. Yagi, Y. Tada, T. Kinouchi, M. Sumiyoshi, T. Miyamoto, T. Yamaguchi, J. Satomi, Y. Uto, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Italy(Venice)
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] Porphyromonas gingivalis lipopolysaccharide enhances the rupture of intracranial aneurysms in rats2016
- Author(s)
  T. Miyamoto, K.T. Kitazato, H. Maekawa, T. Yamaguchi, K. Shimada, K. Yagi, Y. Tada, Y. Kurashiki, S. Yoshioka, Y. Kanematsu, J. Satomi, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Italy(Venice)
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] Activation of M2 macrophages in the late phase of cerebral ischema may contribute to phagocytosis of infract area and neurogenesis2016
- Author(s)
  Y. Kurashiki, K.T. Kitazato, K. Shimada, K. Yagi, Y. Tada, T. Kinouchi, M. Sumiyoshi, T. Miyamoto, T. Yamaguchi, J. Satomi, Y. Uto, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Italy(Venice)
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Activation of M2 macrophages in the late phase of cerebral ischema may contribute to phagocytosis of infract area and neurogenesis2016
- Author(s)
  Y. Kurashiki, K.T. Kitazato, K. Shimada, K. Yagi, Y. Tada, T. Kinouchi, M. Sumiyoshi, T. Miyamoto, T. Yamaguchi, J. Satomi, Y. Uto, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Venice, Italy
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] A Pilot Study of the Mineralocorticoid Receptor Blocker Eplerenone in Hypertensive Patients with Unruptured Cerebral Aneurysms2016
- Author(s)
  J. Satomi, Y. Tada, Y. Kanematsu, K. Kuwayama, K. Yagi, T. Kinouchi, K. Nakajima, N. Matsushita, T. Miyamoto, T. Yamaguchi, M. Korai, H. Mure, K. T. Kitazato, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] Early Morphological Changes in Cerebral Arteries of Cerebral Aneurysm Rupture Model Rats2016
- Author(s)
  H. Maekawa, T. Miyamoto, K.T. Kitazato, K. Yagi, Y. Tada, K. Shimada, J. Satomi, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] Porphyromonas gingivalis lipopolysaccharide enhances the rupture of intracranial aneurysms in rats2016
- Author(s)
  T. Miyamoto, K.T. Kitazato, H. Maekawa, T. Yamaguchi, K. Shimada, K. Yagi, Y. Tada, Y. Kurashiki, S. Yoshioka, Y. Kanematsu, J. Satomi, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Italy(Venice)
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Porphyromonas gingivalis lipopolysaccharide enhances the rupture of intracranial aneurysms in rats2016
- Author(s)
  T. Miyamoto, K.T. Kitazato, H. Maekawa, T. Yamaguchi, K. Shimada, K. Yagi, Y. Tada, Y. Kurashiki, S. Yoshioka, Y. Kanematsu, J. Satomi, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Venice, Italy
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Activation of M2 macrophages in the late phase of cerebral ischema may contribute to phagocytosis of infract area and neurogenesis2016
- Author(s)
  Y. Kurashiki, K.T. Kitazato, K. Shimada, K. Yagi, Y. Tada, T. Kinouchi, M. Sumiyoshi, T. Miyamoto, T. Yamaguchi, J. Satomi, Y. Uto, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Venice, Italy
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Porphyromonas gingivalis lipopolysaccharide enhances the rupture of intracranial aneurysms in rats2016
- Author(s)
  T. Miyamoto, K.T. Kitazato, H. Maekawa, T. Yamaguchi, K. Shimada, K. Yagi, Y. Tada, Y. Kurashiki, S. Yoshioka, Y. Kanematsu, J. Satomi, S. Nagahiro
- Organizer
  25th European Stroke Conference
- Place of Presentation
  Venice, Italy
- Year and Date
  2016-04-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] Early Morphological Changes in Cerebral Arteries of Cerebral Aneurysm Rupture Model Rats2016
- Author(s)
  H. Maekawa, T. Miyamoto, K.T. Kitazato, K. Yagi, Y. Tada, K. Shimada, J. Satomi, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10306
[Presentation] Impact of Periodontal Disease and －Bacteria on Intracranial Aneurysms2016
- Author(s)
  S. Yoshioka, Y. Tada, J. Satomi, K. Yagi, K. Naruishi, K. Kuwayama, K. T. Kitazato, T. Miyamoto, Y. Kanematsu, M. Harada, T. Nagata, S. Nagahiro
- Organizer
  International Stroke Conference
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2016-02-17
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04950
[Presentation] Cyclic nucleotide phosphodiesterase 4-related vascular inflammation contributes to the progression of cerebral aneurysm2009
- Author(s)
  Yagi K, et al.
- Organizer
  XIV World Conress of Neurological Surgery
- Place of Presentation
  Boston, USA
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PROJECT-21390412
[Presentation] Eplerenone suppresses the progression of experimentally-induced cerebral aneurysms in rats2009
- Author(s)
  Tada Y, Kitazato KT, Tamura T, Yagi K, Shimada K, Kinouchi T, Matsushita N, Satomi J, Nagahiro S.
- Organizer
  XIV world Congress of Neurological Surgery
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20591686
[Presentation] Cyclic Nucleotide Phosphodiesterase 4-Related Vascular Inflammation Contributes to the Progression of Cerebral Aneurysms2009
- Author(s)
  Yagi K, Kitazato KT, Tada Y, Tamura T, Matsuzaki K, Satomi J, Nagahiro S.
- Organizer
  XIV world Congress of Neurological Surgery
- Place of Presentation
  Boston, USA
- Data Source
  KAKENHI-PROJECT-20591686
[Presentation] Role of mineral corticoid receptor on experimental cerebral aneurysms in rats 20092009
- Author(s)
  Tada Y, Kitazato KT, Tamura T, Yagi K, Shimada K, Kinouchi T, Satomi J, Nagahiro S.
- Organizer
  The 6th International Intracranial Stent meeting
- Place of Presentation
  Sendai, Japan
- Data Source
  KAKENHI-PROJECT-20591686
[Presentation] Cyclic nucleotide phosphodiesterase 4-related vascular inflammation contributes to the progression of cerebral aneurysm2009
- Author(s)
  Yagi K, et al.
- Organizer
  XTV World Conress of Neurological Surgery
- Place of Presentation
  Boston, USA
- Year and Date
  2009-09-03
- Data Source
  KAKENHI-PROJECT-21591844
[Presentation] Leucocyte adhesion molecules contribute to the development of cerebral aneurysms in rats2008
- Author(s)
  Yagi K, Kitazato KT, Tada Y, Tamura T, Nakajima N, Matsubara S, Nagahiro S.
- Organizer
  6th World Stroke Congress
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-20591686
[Presentation] What should we do to prevent cerebral aneurysm formation and progression2008
- Author(s)
  Nagahiro S, Tamura T, Yagi K, Tada Y, Jamous MA, Uno M, Nakajima N, Matsubara S, Kitazato KT
- Organizer
  6th World Stroke Congress
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-20591686
[Presentation] Role of mineral corticoid receptor on experimental cerebral aneurysms in rats2008
- Author(s)
  Tada Y, Kitazato KT, Tamura T, Yagi K, Shimada K, Kinouchi T, Satomi J, Nagahiro S.
- Organizer
  6th World Stroke Congress
- Place of Presentation
  Vienna, Austria
- Data Source
  KAKENHI-PROJECT-20591686

1. KANEMATSU Yasuhisa (90363142)

# of Collaborated Projects: 8 results

# of Collaborated Products: 12 results
2. TADA Yoshiteru (30547964)

# of Collaborated Projects: 8 results

# of Collaborated Products: 33 results
3. NAGAHIRO Shinji (60145315)

# of Collaborated Projects: 5 results

# of Collaborated Products: 38 results
4. 高麗雅章 (60794013)

# of Collaborated Projects: 4 results

# of Collaborated Products: 3 results
5. SHIMADA Kenji (60624351)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
6. NISHI Kyoko (60335817)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SATA Masataka (80345214)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. SATOMI Junichiro (10304510)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
9. 高木康志 (40312227)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. 宮本健志 (80585000)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
11. 四方英二 (30813315)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. UNO Masaaki (90232884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. MATSUBARA Shunji (60294675)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 中嶌教夫 (00332817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 宇都義浩 (20304553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
16. 桑山一行 (50614236)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
17. 木内智也 (50348968)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山口泉 (70780005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
19. NARUISHI Koji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Yagi Kenji 八木 謙次

YAGI KENJI 八木 謙次

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Activation of M2-type macrophages in the late phase of cerebral ischemia promotes neurogenesis with cleaning of the infarct area.Principal Investigator

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[Journal Article] Activation of the NLRP3/IL-1β/MMP-9 pathway and intracranial aneurysm rupture associated with the depletion of ERα and Sirt1 in oophorectomized rats2023

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[Journal Article] Role of post-ischemic phase-dependent modulation of anti-inflammatory M2-type macrophages against rat brain damage2022

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[Journal Article] An imbalance between RAGE/MR/HMGB1 and ATP1α3 is associated with inflammatory changes in rat brain harboring cerebral aneurysms prone to rupture2022

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[Journal Article] Disequilibrium of plasma protease/anti-protease due to severe periodontal disease contributes to human subarachnoid hemorrhage2020

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[Journal Article] Time-dependent and site-dependent morphological changes in rupture-prone arteries: ovariectomized rat intracranial aneurysm model2019

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[Journal Article] Spot sign predicts rebleeding after endoscopic surgery for intracerebral hemorrhage2018

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Yagi Kenji 八木謙次

YAGI KENJI 八木謙次