HIROSE Yoshinobu 廣瀬敬信

Researcher Number	80555714
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2023: 山口大学, 医学部附属病院, 講師 2014 – 2016: 山口大学, 医学部附属病院, 助教 2012 – 2013: 山口大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator 内耳保護 / 側線器有毛細胞 / ゼブラフィッシュ / 有毛細胞 / 側線器 / 内耳障害 / スクリーニング / オートファジー / 卵形嚢有毛細胞 / 聴覚医学 / 難聴 / 内耳障害保護 / セブラフィッシュ … More Except Principal Investigator … More 難聴 / 内耳 / 糖尿病 / 有毛細胞 / 側線器 / ゼブラフィッシュ / 遺伝性難聴 / 遺伝子 / 終末糖化産物 / 卵形嚢培養 / 内耳感覚細胞障害 / 内耳有毛細胞 / メタボリック症候群 / 加齢 / アンチエイジング / 生活習慣病 / 老化 / メタボリックシンドローム Less

Elucidation of Hair Cell Dysfunction Mechanisms Using Genetically Modified Zebrafish
- Principal Investigator
  
  Yamashita Hiroshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamaguchi University
ゼブラフィッシュ側線器有毛細胞を用いた内耳におけるオートファジーの役割の解明Principal Investigator
- Principal Investigator
  
  廣瀬敬信
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamaguchi University
The role of advanced glycation end products in the deafness associated with diabetes
- Principal Investigator
  
  SUGAHARA Kazuma
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Yamaguchi University
Screening of drugs using zebrafish lateral lines hair cell synaptic disorder modelPrincipal Investigator
- Principal Investigator
  
  HIROSE Yoshinobu
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamaguchi University
The relationship between hearing loss and vascular disorders in metabolic syndrome patients
- Principal Investigator
  
  YAMASHITA Hiroshi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamaguchi University
Evaluation of expressed gene in the inner ear with RNA interference method
- Principal Investigator
  
  SUGAHARA Kazuma
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamaguchi University
Screening for a protective effect in cochlear hair cells using candidate drugs in the zebrafish lateral linePrincipal Investigator
- Principal Investigator
  
  HIROSE Yoshinobu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamaguchi University
The relationship between the metabolic syndrome and presbycusis
- Principal Investigator
  
  YAMASHITA Hiroshi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Yamaguchi University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] Protective effect of astaxanthin nanoemulsion on mammalian inner ear hair cells2023
- Author(s)
  Kobayashi Yuki、Sugahara Kazuma、Takemoto Yosuke、Tsuda Junko、Hirose Yoshinobu、Hashimoto Makoto、Yamashita Hiroshi
- Journal Title
  
  PeerJ
  
  Volume: 11 Pages: e15562-e15562
- DOI
  10.7717/peerj.15562
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09727, KAKENHI-PROJECT-19K09870, KAKENHI-PROJECT-20K09733
[Journal Article] Postoperative Hypothyroidism After Hemithyroidectomy2022
- Author(s)
  Shimogori Hiroaki、Hirose Yoshinobu、Sugahara Kazuma、Yamashita Hiroshi
- Journal Title
  
  Practica Oto-Rhino-Laryngologica
  
  Volume: 115 Issue: 3 Pages: 245-248
- DOI
  10.5631/jibirin.115.245
- NAID
  130008165498
- ISSN
  0032-6313, 1884-4545
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321, KAKENHI-PROJECT-20K09733
[Journal Article] 当科における最近5年間の誤嚥防止術の検討.2021
- Author(s)
  坂本めい, 津田潤子, 菅原一真, 広瀬敬信, 樽本俊介, 橋本智子, 橋本　誠, 原浩貴, 山下裕司.
- Journal Title
  
  口腔・咽頭科.
  
  Volume: 34 Pages: 47-51
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] 当科における最近5年間の誤嚥防止術の検討.2021
- Author(s)
  坂本めい, 津田潤子, 菅原一真, 広瀬敬信, 樽本俊介, 橋本智子, 橋本　誠, 原浩貴, 山下裕司.
- Journal Title
  
  口腔・咽頭科
  
  Volume: 34 Pages: 47-51
- Data Source
  KAKENHI-PROJECT-20K09733
[Journal Article] Effect of preservation on the physical and chemical properties of the temporal fascia2020
- Author(s)
  Tarumoto Shunsuke、Sugahara Kazuma、Hashimoto Makoto、Hirose Yoshinobu、Tsuda Junko、Takemoto Yosuke、Fujii Hironori、Matsuura Takafumi、Shimogori Hiroaki、Ohgi Junji、Yamashita Hiroshi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 47 Issue: 3 Pages: 377-382
- DOI
  10.1016/j.anl.2019.12.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321, KAKENHI-PROJECT-20K09733
[Journal Article] 内頸静脈の腫瘍塞栓をきたした甲状腺乳頭癌の１例.2019
- Author(s)
  眞﨑達也, 竹本洋介, 堀　健志, 広瀬敬信, 橋本　誠, 菅原一真, 山下裕司.
- Journal Title
  
  耳鼻咽喉科・頭頸部外科.
  
  Volume: 91 Pages: 257-262
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] LOXHD1b遺伝子knockoutゼブラフィッシュの作成について2019
- Author(s)
  樽本俊介, 浅岡洋一, 菅原一真, 広瀬敬信, 竹本洋介, 清木誠, 山下裕司
- Journal Title
  
  耳鼻咽喉科ニューロサイエンス
  
  Volume: 33 Pages: 29-31
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] 基礎研究の将来展望 Zebrafish側線器有毛細胞を用いた内耳障害・保護薬物のスクリーニング2019
- Author(s)
  広瀬敬信, 菅原一真, 竹本洋介, 樽本俊介, 橋本誠, 藤井博則, 山下裕司
- Journal Title
  
  Equilibrium Research
  
  Volume: 78 Pages: 212-218
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] Erratum to “Protective effect of an astaxanthin nanoemulsion against neomycin-induced hair-cell damage in zebrafish” [Auris Nasus Larynx 45 (2018) 20-25]2019
- Author(s)
  Takemoto Yosuke、Hirose Yoshinobu、Sugahara Kazuma、Hashimoto Makoto、Hara Hirotaka、Yamashita Hiroshi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 46 Issue: 3 Pages: 484-484
- DOI
  10.1016/j.anl.2018.11.010
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] 補聴器耳型採取時の印象材による中耳異物症例2019
- Author(s)
  沖中洋介, 菅原一真, 松浦貴文, 樽本俊介, 広瀬敬信, 橋本誠, 下郡博明, 山下裕司
- Journal Title
  
  Otology Japan
  
  Volume: 29 Pages: 180-184
- NAID
  130007751169
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] 内頸静脈の腫瘍塞栓をきたした甲状腺乳頭癌の１例.2019
- Author(s)
  眞﨑達也, 竹本洋介, 堀　健志, 広瀬敬信, 橋本　誠, 菅原一真, 山下裕司.
- Journal Title
  
  耳鼻咽喉科・頭頸部外科.
  
  Volume: 91 Pages: 257-262
- Data Source
  KAKENHI-PROJECT-15K10753
[Journal Article] 中咽頭巨大AVMに対する硬化療法施行例2019
- Author(s)
  眞崎達也, 菅原一真, 堀健志, 津田潤子, 広瀬敬信, 橋本誠, 山下裕司
- Journal Title
  
  口腔・咽頭科
  
  Volume: 32 Pages: 27-133
- NAID
  130007853465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] Oral administration of an herbal medicine to prevent progressive hearing loss in a mouse model of diabetes2019
- Author(s)
  Hori Takeshi、Sugahara Kazuma、Tsuda Junko、Hirose Yoshinobu、Hashimoto Makoto、Takemoto Yousuke、Tarumoto Shunsuke、Yamashita Hiroshi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: - Issue: 5 Pages: 703-708
- DOI
  10.1016/j.anl.2019.01.011
- NAID
  130007993624
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10753, KAKENHI-PROJECT-18K09321
[Journal Article] 甲状腺を貫通した咽頭外魚骨異物例2019
- Author(s)
  堀健志, 菅原一真, 津田潤子, 山本陽平, 小林由貴, 橋本誠, 広瀬敬信, 山下裕司
- Journal Title
  
  耳鼻咽喉科臨床
  
  Volume: 112 Pages: 391-395
- NAID
  130007657412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] 再発性早期胃管癌に合併した下咽頭梨状陥凹癌の1例2019
- Author(s)
  西村省吾, 菅原一真, 堀健志, 竹本洋介, 樽本俊介, 津田潤子, 廣瀬敬信, 山下裕司
- Journal Title
  
  耳鼻咽喉科・頭頸部外科
  
  Volume: 91 Pages: 478-482
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K09321
[Journal Article] Oral administration of geranylgeranylacetone to protect vestibular hair cells2018
- Author(s)
  Nagato Shinpei、Sugahara Kazuma、Hirose Yoshinobu、Takemoto Yousuke、Hashimoto Makoto、Fujii Hironori、Yamashita Hiroshi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 45 Issue: 3 Pages: 412-416
- DOI
  10.1016/j.anl.2017.07.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10752, KAKENHI-PROJECT-15K10753, KAKENHI-PROJECT-15K10751
[Journal Article] Protective effect of an astaxanthin nanoemulsion against neomycin-induced hair-cell damage in zebrafish2018
- Author(s)
  Takemoto Yosuke、Hirose Yoshinobu、Sugahara Kazuma、Hashimoto Makoto、Hara Hirotaka、Yamashita Hiroshi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 45 Issue: 1 Pages: 20-25
- DOI
  10.1016/j.anl.2017.02.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10752, KAKENHI-PROJECT-15K10753, KAKENHI-PROJECT-15K10751
[Journal Article] Quantitative Analysis of Smooth Pursuit Eye Movement Using Video-Oculography2018
- Author(s)
  Hironori Fujii, Makoto Hashimoto, Kazuma Sugahara, Takuo Ikeda, Yoshinobu Hirose, Hiroshi Yamashita
- Journal Title
  
  Archives of Otolaryngology and Rhinology
  
  Volume: - Pages: 030-034
- DOI
  10.17352/2455-1759.000071
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09321, KAKENHI-PROJECT-15K10752, KAKENHI-PROJECT-15K10753
[Journal Article] ビデオ画像解析によるマウス嗅覚評価法について2017
- Author(s)
  菅原一真, 竹本洋介, 広瀬敬信, 橋本　誠, 山下裕司
- Journal Title
  
  耳鼻咽喉科ニューロサイエンス
  
  Volume: 31 Pages: 65-67
- Data Source
  KAKENHI-PROJECT-15K10753
[Journal Article] ゼブラフィッシュ側線器有毛細胞死におけるKinaseの役割～Kinase inhibitor を用いた試み～2017
- Author(s)
  竹本洋介, 広瀬敬信, 菅原一真, 橋本　誠, 山下裕司
- Journal Title
  
  耳鼻咽喉科ニューロサイエンス
  
  Volume: 31 Pages: 31-32
- NAID
  130005606463
- Data Source
  KAKENHI-PROJECT-15K10753
[Journal Article] 小児自律性機能性甲状腺結節の一例.2017
- Author(s)
  岩本　文, 菅原一真, 広瀬敬信, 原浩貴, 橋本　誠, 山下裕司
- Journal Title
  
  小児耳鼻咽喉科
  
  Volume: 38 Pages: 8-13
- NAID
  130005682201
- Data Source
  KAKENHI-PROJECT-15K10753
[Journal Article] Quercetin protects against hair cell loss in the zebrafish lateral line and guinea pig cochlea.2016
- Author(s)
  Yoshinobu Hirose, Kazuma Sugahara, Eiju Kanagawa, Yousuke Takemoto, Makoto Hashimoto, Hiroshi Yamashita.
- Journal Title
  
  Hearing Research.
  
  Volume: 342 Pages: 80-85
- DOI
  10.1016/j.heares.2016.10.001
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10751, KAKENHI-PROJECT-15K10752, KAKENHI-PROJECT-15K10753
[Journal Article] テプレノンは強大音によるシナプス障害を抑制できるか.2015
- Author(s)
  岡崎吉紘, 菅原一真, 広瀬敬信, 下郡博明, 山下裕司.
- Journal Title
  
  耳鼻咽喉科ニューロサイエンス
  
  Volume: 29 Pages: 49-50
- Data Source
  KAKENHI-PROJECT-15K10751
[Journal Article] The minimum peptides of IGF-1 and substance P protect vestibular hair cells against neomycin ototoxicity.2015
- Author(s)
  S. Yoshida, K. Sugahara, M. Hashimoto, Y. Hirose, H. Shimogori, H. Yamashita.
- Journal Title
  
  Acta Oto-Laryngologica
  
  Volume: 135 Pages: 411-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592551
[Journal Article] The minimum peptides of IGF-1 and substance P protect vestibular hair cells against neomycin ototoxicity.2015
- Author(s)
  Shuhei Yoshida, Kazuma Sugahara, Makoto Hashimoto, Yoshinobu Hirose, Hiroaki Shimogori, Hiroshi Yamashita.
- Journal Title
  
  Acta Oto-Laryngologica.
  
  Volume: 135 Issue: 5 Pages: 411-411
- DOI
  10.3109/00016489.2014.979438
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K10751, KAKENHI-PROJECT-15K10753
[Journal Article] Coenzyme Q10 Protects Hair Cells against Aminoglycoside2014
- Author(s)
  K. Sugahara，H. Hirose, T. Mikuriya, M. Hashimoto, E. Kanagawa, H. Hara, H. Shimogori, H. Yamashita
- Journal Title
  
  PLoS One
  
  Volume: 9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24592551
[Journal Article] Pathology of the inner ear after acoustic injury.2014
- Author(s)
  E. Kanagawa, K. Sugahara, Y. Hirose, T. Mikuriya, H. Shimogori, H. Yamashita
- Journal Title
  
  Bull Yamaguchi Med Sch
  
  Volume: 61 Pages: 1-6
- NAID
  120005477819
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592551
[Journal Article] Effects of substance P during the recovery of hearing function after noise-induced hearing loss.2014
- Author(s)
  E. Kanagawa, K. Sugahara, Y. Hirose, T. Mikuriya, H. Shimogori, H. Yamashita.
- Journal Title
  
  Brain Res
  
  Volume: 1582 Pages: 187-96
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592551
[Journal Article] 音響障害後における内有毛細胞シナプス数の経時的変化2013
- Author(s)
  金川英寿, 菅原一真, 広瀬敬信, 御厨剛史, 下郡博明, 山下裕司
- Journal Title
  
  耳鼻咽喉科ニューロサイエンス
  
  Volume: 27 Pages: 22-24
- Data Source
  KAKENHI-PROJECT-24592551
[Journal Article] ゼブラフィッシュ側線有毛細胞を用いた抗癌剤のスクリーニング2013
- Author(s)
  広瀬敬信，菅原一真，山下裕司
- Journal Title
  
  耳鼻咽喉科ニューロサイエンス
  
  Volume: 27 Pages: 83-85
- Data Source
  KAKENHI-PROJECT-24592551
[Presentation] STRC 遺伝子 knock out ゼブラフィッシュの作成について2021
- Author(s)
  岩本　文，樽本俊介，菅原一真，広瀬敬信，橋本　誠，山下裕司
- Organizer
  第122回日本耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] STRC 遺伝子 knock out ゼブラフィッシュの作成について2021
- Author(s)
  岩本　文，樽本俊介，菅原一真，広瀬敬信，橋本　誠，山下裕司
- Organizer
  第122回日本耳鼻咽喉科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] STRC 遺伝子 knock out ゼブラフィッシュの作成について2021
- Author(s)
  岩本　文，菅原一真，広瀬敬信，橋本　誠，山下裕司
- Organizer
  第66回日本聴覚医学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] LOXHD1b遺伝子ノックアウトゼブラフィッシュの行動解析について2020
- Author(s)
  樽本俊介，浅岡洋一，菅原一真，広瀬敬信，松浦貴文，橋本　誠，清木　誠，山下裕司
- Organizer
  第121回日本耳鼻咽喉科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] 肺結核治療と並行して化学放射線療法を行った中咽頭癌の 1 例2020
- Author(s)
  松浦貴文，広瀬敬信，菅原一真，山下裕司
- Organizer
  第8回日本耳鼻咽喉科感染症・エアロゾル学会
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] 副甲状腺癌の2症例2020
- Author(s)
  堀　健志，竹本洋介，広瀬敬信，山下裕司
- Organizer
  第121回日本耳鼻咽喉科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] ステロイド投与と手術加療により奏功した軟部好酸球性肉芽種症の一例2020
- Author(s)
  樽本俊介，竹本洋介，堀　健志，広瀬敬信，松浦貴文，坂本めい，橋本　誠，山下裕司
- Organizer
  第46回日本耳鼻咽喉科学会中国地方部会連合講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] LOXHD1b 遺伝子ノックアウトゼブラフィッシュの行動解析について2020
- Author(s)
  樽本俊介，菅原一真，広瀬敬信，橋本　誠，松浦貴文，山下裕司
- Organizer
  第30回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] 両側軟部好酸球性肉芽腫に手術加療を行った 1 症例2020
- Author(s)
  竹本洋介，眞_達也，堀　健志，広瀬敬信，山下裕司
- Organizer
  第82回日本耳鼻咽喉科臨床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] 化学放射線治療中の頭頸部癌患者に対する半夏瀉心湯の効果2020
- Author(s)
  竹本洋介，堀　健志，広瀬敬信，山下裕司
- Organizer
  第44回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] Expression of advanced glycation end-product (AGEs) in the cultured utricles2020
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Makoto Hashimoto，Shunsuke Tarumoto，Hiroshi Yamashita
- Organizer
  43rd ARO Annual Midwinter Meeting San Jose（USA　）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] 悪性化を認めた上咽頭乳頭腫の 1 例2020
- Author(s)
  岩本　文，津田潤子，橋本智子，橋本　誠，沖中洋介，眞_達也，広瀬敬信，山下裕司
- Organizer
  第46回日本耳鼻咽喉科学会中国地方部会連合講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] 両側扁桃周囲膿瘍を認めた小児例2020
- Author(s)
  松浦貴文，広瀬敬信，菅原一真，山下裕司
- Organizer
  第8回日本耳鼻咽喉科感染症・エアロゾル学会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] 涙のう原発悪性黒色腫の 1 例2020
- Author(s)
  広瀬敬信，堀　健志，竹本洋介，山下裕司
- Organizer
  第44回日本頭頸部癌学会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] LOXHD1b遺伝子ノックアウトゼブラフィッシュの行動解析について2020
- Author(s)
  樽本俊介，浅岡洋一，菅原一真，広瀬敬信，松浦貴文，橋本　誠，清木　誠，山下裕司
- Organizer
  第121回日本耳鼻咽喉科学会学術講演会
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] LOXHD1b 遺伝子ノックアウトゼブラフィッシュの行動解析について2020
- Author(s)
  樽本俊介，菅原一真，広瀬敬信，橋本　誠，松浦貴文，山下裕司
- Organizer
  第30回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] 当科で加療を行った咽喉頭血管奇形症例の検討2020
- Author(s)
  津田潤子，広瀬敬信，眞崎達也，沖中洋介，小林由貴，山下裕司
- Organizer
  第121回日本耳鼻咽喉科学会学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] 悪性化を認めた上咽頭乳頭腫の1例2020
- Author(s)
  岩本　文，津田潤子，広瀬敬信，山下裕司
- Organizer
  第82回日本耳鼻咽喉科臨床学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-20K09733
[Presentation] Screening Hair Cell Protection in Autophagy Library using the zebrafish lateral line2020
- Author(s)
  Yoshinobu Hirose, Kazuma Sugahara, Makoto Hashimoto, Hiroshi Yamashita
- Organizer
  Association for Research in Otolaryngology The 43th Annual MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09892
[Presentation] ゼブラフィッシュ側線有毛細胞障害モデルを用いたオートファジー化合物のスクリーニング2019
- Author(s)
  広瀬敬信、菅原一真、竹本洋介、樽本俊介、山下裕司
- Organizer
  第29回日本耳科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-19K09892
[Presentation] Expression of advanced glycation end-product (AGEs) in the cultured utricles2019
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Shunsuke Tarumoto，Makoto Hashimoto，Hiroshi Yamashita
- Organizer
  The 56th Inner Ear Biology Workshop Padua（Italy）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] Expression of advanced glycation end-product in the cultured utricles2019
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Makoto Hashimoto，Shunsuke Tarumoto，Hiroshi Yamashita
- Organizer
  42nd ARO Annual MidWinter Meeting Baltimore（US）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] Screening Hair Cell Protection in Autophagy Library using the zebrafish lateral line2019
- Author(s)
  Yoshinobu Hirose, Kazuma Sugahara, Makoto Hashimoto, Hiroshi Yamashita
- Organizer
  Symposium & 56th Inner Ear Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11182
[Presentation] Expression of advanced glycation end-product in the cultured utricles2019
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Makoto Hashimoto，Shunsuke Tarumoto，Hiroshi Yamashita
- Organizer
  42nd ARO Annual MidWinter Meeting Baltimore（US）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] マウス卵形嚢培養における終末糖化産物の生成2019
- Author(s)
  菅原一真，狩野有加莉，広瀬敬信，橋本　誠，山下裕司
- Organizer
  第29回日本耳科学会総会・学術講演会山形
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] ゼブラフィッシュ側線器有毛細胞に対する炎症性サイトカインの影響2018
- Author(s)
  菅原一真，樽本俊介，山本陽平，広瀬敬信，山下裕司
- Organizer
  第28回日本耳科学会総会・学術講演会大阪
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] Hair cell cytotoxicity model of zebrafish lateral line by ultrasonic generator2018
- Author(s)
  Yoshinobu Hirose, Kazuma Sugahara, Yousuke Takemoto, Makoto Hashimoto, Hiroshi Yamashita
- Organizer
  Association for Research in Otolaryngology 41st Annual MidWinter Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11182
[Presentation] 炎症性サイトカインが側線器有毛細胞に及ぼす影響について2018
- Author(s)
  菅原一真，広瀬敬信，橋本　誠，山下裕司
- Organizer
  第119回日本耳鼻咽喉科学会総会・学術講演会横浜
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] Expression of advanced glycation end-product in the cochlea of metabolic syndrome model mice2018
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Makoto Hashimoto，Yosuke Takemoto，Shunsuke Tarumoto，Hiroshi Yamashita
- Organizer
  41st ARO Annual MidWinter Meeting San Diego（USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] ゼブラフィッシュ側線器有毛細胞に対する炎症性サイトカインの影響2018
- Author(s)
  菅原一真，樽本俊介，山本陽平，広瀬敬信，山下裕司
- Organizer
  第28回日本耳科学会総会・学術講演会大阪
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] Quantitative analysis of smooth pursuit eye movement by video-oculography (VOG)2018
- Author(s)
  Kazuma Sugahara，Hironori Fujii，Makoto Hashimoto，Yoshinobu Hirose，Takuo Ikeda，Hiroshi Yamashita
- Organizer
  XXX Barany Society Meeting Uppsala（Sweden）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] 聴覚補充現象に漢方薬が有効であった症例2018
- Author(s)
  菅原一真，橋本　誠，小林由貴，広瀬敬信，瀬川　誠，山下裕司
- Organizer
  第34回日本耳鼻咽喉科漢方研究会学術集会東京
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] Quantitative analysis of smooth pursuit eye movement by video-oculography (VOG)2018
- Author(s)
  Kazuma Sugahara，Hironori Fujii，Makoto Hashimoto，Yoshinobu Hirose，Takuo Ikeda，Hiroshi Yamashita
- Organizer
  XXX Barany Society Meeting Uppsala（Sweden）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] 聴覚補充現象に漢方薬が有効であった症例2018
- Author(s)
  菅原一真，橋本　誠，小林由貴，広瀬敬信，瀬川　誠，山下裕司
- Organizer
  第34回日本耳鼻咽喉科漢方研究会学術集会東京
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] Expression of advanced glycation end-product in the cochlea of metabolic syndrome model mice2018
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Makoto Hashimoto，Yosuke Takemoto，Shunsuke Tarumoto，Hiroshi Yamashita
- Organizer
  41st ARO Annual MidWinter Meeting San Diego（USA）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10751
[Presentation] 炎症性サイトカインが側線器有毛細胞に及ぼす影響について2018
- Author(s)
  菅原一真，広瀬敬信，橋本　誠，山下裕司
- Organizer
  第119回日本耳鼻咽喉科学会総会・学術講演会横浜
- Data Source
  KAKENHI-PROJECT-18K09321
[Presentation] 超音波によるzebrafish側線器有毛細胞障害モデル作成の試み2017
- Author(s)
  広瀬敬信、菅原一真、竹本洋介、山下裕司
- Organizer
  日本耳鼻咽喉科学会総会
- Data Source
  KAKENHI-PROJECT-16K11182
[Presentation] Effect of pyridoxamine on the hearing function in the mouse model of metabolic syndrome2017
- Author(s)
  Kazuma Sugahara，Junko Tsuda，Takeshi Hori，Yoshinobu Hirose，Makoto Hashimoto，Hiroshi Yamashita
- Organizer
  40th ARO Annual MidWinter Meeting
- Place of Presentation
  Baltimore (USA)
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] 超音波発生装置によるzebrafish側線器有毛細胞障害モデル作成の試み2017
- Author(s)
  広瀬敬信、菅原一真、竹本洋介、山下裕司
- Organizer
  第35回耳鼻咽喉科ニューロサイエンス研究会
- Data Source
  KAKENHI-PROJECT-16K11182
[Presentation] Effect of pyridoxamine on the hearing function in the mouse model of metabolic syndrome2017
- Author(s)
  Kazuma Sugahara，Junko Tsuda，Takeshi Hori，Yoshinobu Hirose，Makoto Hashimoto，Hiroshi Yamashita
- Organizer
  40th ARO Annual MidWinter Meeting
- Place of Presentation
  Baltimore（USA）
- Year and Date
  2017-02-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10751
[Presentation] zebrafish側線器有毛細胞音波障害モデルのメカニズム2017
- Author(s)
  広瀬敬信、菅原一真、竹本洋介、山下裕司
- Organizer
  日本耳科学会
- Data Source
  KAKENHI-PROJECT-16K11182
[Presentation] メタボリック症候群モデルマウス内耳における終末糖化産物の生成2017
- Author(s)
  菅原一真，津田潤子，廣瀬敬信，山下裕司
- Organizer
  第27回日本耳科学会総会・学術講演会横浜
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] メタボリック症候群モデルマウスにおける糖化最終産物と難聴の関係2017
- Author(s)
  菅原一真，竹本洋介，廣瀬敬信，橋本　誠，山下裕司
- Organizer
  第118回日本耳鼻咽喉科学会通常総会・学術講演会広島
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] メタボリック症候群モデル動物におけるAGE産生と難聴について2017
- Author(s)
  菅原一真，津田潤子，堀　健志，廣瀬敬信，原　浩貴，山下裕司
- Organizer
  第17回日本抗加齢医学会総会東京
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] zebrafish側線器有毛細胞の音波障害モデル作成の試み2016
- Author(s)
  広瀬敬信、菅原一真、竹本洋介、山下裕司
- Organizer
  第26回日本耳科学会
- Place of Presentation
  ホテル国際21（長野県長野市）
- Year and Date
  2016-10-05
- Data Source
  KAKENHI-PROJECT-16K11182
[Presentation] Protective Effect in Herbal Medicine "SHIMOTSUTO" in the Zebrafish Lateral Line and Mice Vestibular Hair Cell.2016
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Yousuke Takemoto，Makoto Hashimoto，Hiroshi Yamashita
- Organizer
  29th Barany Sciety Meeting
- Place of Presentation
  Seoul（Korea）
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10751
[Presentation] Protective Effect in Herbal Medicine "SHIMOTSUTO" in the Zebrafish Lateral Line and Mice Vestibular Hair Cell.2016
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Yousuke Takemoto，Makoto Hashimoto，Hiroshi Yamashita
- Organizer
  29th Barany Sciety Meeting 2016
- Place of Presentation
  Seoul（Korea）
- Year and Date
  2016-06-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] げっ歯類を用いた漢方薬の内耳保護効果-zebrafish側線器有毛細胞障害モデルのスクリーニング結果から-2016
- Author(s)
  広瀬敬信、菅原一真、山下裕司
- Organizer
  第117回日本耳鼻咽喉科学会通常総会・学術講演会
- Place of Presentation
  名古屋市（名古屋国際会議場）
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] Age related hearing loss in the mouse model of metabolic syndrome.2016
- Author(s)
  Kazuma Sugahara，Junko Tsuda，Takeshi Hori，Yoshinobu Hirose，Makoto Hashimoto，Hirotaka Hara，Hiroshi Yamashita
- Organizer
  The 16th Japan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
- Place of Presentation
  Shinjuku, Tokyo (Hyatt Regency Tokyo)
- Year and Date
  2016-03-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10751
[Presentation] Age related hearing loss in the mouse model of metabolic syndrome.2016
- Author(s)
  Kazuma Sugahara，Junko Tsuda，Takeshi Hori，Yoshinobu Hirose，Makoto Hashimoto，Hirotaka Hara，Hiroshi Yamashita
- Organizer
  The 16th Japan-Korea Joint Meeting of Otorhinolaryngology-Head and Neck Surgery
- Place of Presentation
  Shinjuku, Tokyo (Hyatt Regency Tokyo)
- Year and Date
  2016-03-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] メタボリック症候群モデルマウスにおける難聴予防の試み2016
- Author(s)
  菅原一真，津田潤子，広瀬敬信，竹本洋介，樽本俊介，山下裕司
- Organizer
  第26回日本耳科学会総会・学術講演会
- Place of Presentation
  ホテル国際21（長野県長野市）
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-15K10751
[Presentation] Protective effect in herbal medicine “Shimotsuto” using the zebrafish lateral line and CBA/N mice vestibular hair cells2016
- Author(s)
  Yoshinobu Hirose, Kazuma Sugahara, Makoto Hashimoto, Hiroshi Yamashita
- Organizer
  39th Association for Research in Otolaryngology Annual MidWinter Meeting
- Place of Presentation
  米国　サンフランシスコ
- Year and Date
  2016-02-21
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] Astaxanthin nano emulsion can protect hair cells against aminoglycosides.2016
- Author(s)
  Kazuma Sugahara，Yoshinobu Hirose，Yosuke Takemoto，Makoto Hashimoto，Hiroshi Yamashita
- Organizer
  39th ARO Annual MidWinter Meeting
- Place of Presentation
  San Diego（USA）
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] 老化内耳における細胞内凝集体の形成について2015
- Author(s)
  菅原一真，津田潤子，広瀬敬信，橋本　誠，岡崎吉紘，竹本洋介，下郡博明，山下裕司
- Organizer
  第116回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  東京都千代田区（東京国際フォーラム）
- Year and Date
  2015-05-21
- Data Source
  KAKENHI-PROJECT-15K10753
[Presentation] The Effect of Oriental Herbal Medicine and Calorie Restriction on the Age-related Hearing Loss of TSOD Mouse2015
- Author(s)
  Takeshi Hori, Kazuma Sugahara, Junko Tsuda, Yoshinobu Hirose, Makoto Hashimoto, Hiroaki Shimogori, Hiroshi Yamashita
- Organizer
  The 2015 ARO Midwinter Meeting
- Place of Presentation
  Baltimore（USA）
- Year and Date
  2015-02-24
- Data Source
  KAKENHI-PROJECT-24592551
[Presentation] モルモットを用いた音響障害に対する四物湯の内耳保護効果-ゼブラフッシュ側線器有毛細胞障害モデルのスクリーニング結果から-2015
- Author(s)
  広瀬敬信、菅原一真、山下裕司
- Organizer
  第31回日本耳鼻咽喉科漢方研究会学術集会
- Place of Presentation
  東京都港区（グランドセントラルタワー3階）
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] げっ歯類を用いた四物湯の内耳保護効果-zebrafish 側線器有毛細胞障害モデルのスクリーニング結果から-2015
- Author(s)
  広瀬敬信，菅原一真，山下裕司
- Organizer
  第25回　日本耳科学会総会・学術講演会
- Place of Presentation
  長崎市（長崎ブリックホール）
- Year and Date
  2015-10-07
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] メタボリックシンドロームモデルマウスTSODにおける加齢と難聴について2014
- Author(s)
  津田潤子，菅原一真，堀　健志，廣瀬敬信，御厨剛史，山下裕司
- Organizer
  日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  福岡市（ヒルトン福岡シーホーク）
- Year and Date
  2014-05-14
- Data Source
  KAKENHI-PROJECT-24592551
[Presentation] The Efficiency of Bofutsushosan and Daisaikoto, an Oriental Herbal Medicine to Prevent the Presbycusis of TSOD Mouse2014
- Author(s)
  Takeshi Hori, Kazuma Sugahara, Junko Tsuda, Yoshinobu Hirose, Hiroaki Shimogori, Makoto Hashimoto, Hiroshi Yamashita
- Organizer
  37th Annual MidWinter Research Meeting of the Association for Research in Otolaryngology
- Place of Presentation
  San Diego（USA）
- Data Source
  KAKENHI-PROJECT-24592551
[Presentation] Screening for protective effect in Kampo Medicine（Herbal medicine) using the zebrafish lateral line2014
- Author(s)
  Yoshinobu Hirose, Kazuma Sugahara, Hiroshi Yamashita
- Organizer
  Association for Research in Otolaryngology 38th Annual MidWinter Meeting
- Place of Presentation
  米国サンディエゴ（ Manchester Grand Hyatt Hotel）Grand Hall A-B-C
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] ゼブラフィッシュ側線有毛細胞障害モデルを用いた漢方薬のスクリーニング2014
- Author(s)
  広瀬敬信菅原一真山下裕司
- Organizer
  第30回日本耳鼻咽喉科漢方研究会学術集会
- Place of Presentation
  THE GRAND HALL （東京都港区）
- Year and Date
  2014-10-25
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] ゼブラフィッシュ側線器有毛細胞を用いた創薬に向けた研究2013
- Author(s)
  広瀬敬信、菅原一真、山下裕司
- Organizer
  日本耳科学会
- Place of Presentation
  宮崎市（シーガイアコンベンションセンター）第2会場
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] ゼブラフィッシュ側線有毛細胞障害モデルを用いたサプリメントのスクリーニング2013
- Author(s)
  広瀬敬信、菅原一真、金川英寿、下郡博明、山下裕司
- Organizer
  日本耳鼻咽喉科学会
- Place of Presentation
  札幌市（ロイトン札幌）第10会場
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] ゼブラフィッシュ側線有毛細胞障害モデルを用いた漢方薬のスクリーニング
- Author(s)
  広瀬敬信菅原一真下郡博明山下裕司
- Organizer
  第24回日本耳科学会総会学術講演会
- Place of Presentation
  朱鷺メッセ（新潟県新潟市）
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] ゼブラフィッシュ側線有毛細胞障害モデルを用いた漢方薬のスクリーニング
- Author(s)
  広瀬敬信菅原一真下郡博明山下裕司
- Organizer
  第115回日本耳鼻咽喉科学会総会・学術講演会
- Place of Presentation
  ヒルトン福岡シーホーク（福岡県福岡市）
- Year and Date
  2014-05-14 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25861564
[Presentation] ゼブラフィッシュ側線有毛細胞障害モデルを用いた漢方薬のスクリーニング
- Author(s)
  広瀬敬信菅原一真山下裕司
- Organizer
  第73回日本めまい平衡医学会総会・学術講演会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-11-05 – 2014-11-07
- Data Source
  KAKENHI-PROJECT-25861564

1. SUGAHARA Kazuma (20346555)

# of Collaborated Projects: 7 results

# of Collaborated Products: 74 results
2. YAMASHITA Hiroshi (00210419)

# of Collaborated Projects: 5 results

# of Collaborated Products: 76 results
3. SHIMOGORI Hiroaki (70226273)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 原浩貴 (90274167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
5. 橋本誠 (50343299)

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results

HIROSE Yoshinobu 廣瀬 敬信

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Elucidation of Hair Cell Dysfunction Mechanisms Using Genetically Modified Zebrafish

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ゼブラフィッシュ側線器有毛細胞を用いた内耳におけるオートファジーの役割の解明Principal Investigator

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The role of advanced glycation end products in the deafness associated with diabetes

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Screening of drugs using zebrafish lateral lines hair cell synaptic disorder modelPrincipal Investigator

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The relationship between hearing loss and vascular disorders in metabolic syndrome patients

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Evaluation of expressed gene in the inner ear with RNA interference method

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Screening for a protective effect in cochlear hair cells using candidate drugs in the zebrafish lateral linePrincipal Investigator

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The relationship between the metabolic syndrome and presbycusis

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[Journal Article] Protective effect of astaxanthin nanoemulsion on mammalian inner ear hair cells2023

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[Journal Article] Postoperative Hypothyroidism After Hemithyroidectomy2022

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[Journal Article] 当科における最近5年間の誤嚥防止術の検討.2021

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[Journal Article] 当科における最近5年間の誤嚥防止術の検討.2021

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[Journal Article] Effect of preservation on the physical and chemical properties of the temporal fascia2020

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[Journal Article] 内頸静脈の腫瘍塞栓をきたした甲状腺乳頭癌の１例.2019

Author(s)

HIROSE Yoshinobu 廣瀬敬信