AYABE Tadayuki 綾部匡之

Researcher Number	80566555
Other IDs
Affiliation (based on the past Project Information) *help	2016 – 2018: 国立研究開発法人国立成育医療研究センター, 生体防御系内科部, 研究員 2015: 国立研究開発法人国立成育医療研究センター, その他部局等, 研究員 2014: 独立行政法人国立成育医療研究センター, 分子内分泌研究部, 研究員 2013 – 2014: 独立行政法人国立成育医療研究センター, その他部局等, 研究員
Review Section/Research Field	Principal Investigator Pediatrics Except Principal Investigator Metabolomics / Human genetics
Keywords	Principal Investigator 食行動異常 / SGLT2阻害薬 / 糖尿病 / オレキシン / 日中過眠 / プラダー・ウィリ症候群 Except Principal Investigator 遺伝子 / 疾患 / 疾患感受性 / 糖尿病 … More / 感受性 / 染色体 / 染色体微細構造異常 / ゲノム / 細胞遺伝学 Less

Clarification of molecular basis of type 1 diabetes using novel technologies
- Principal Investigator
  
  Fukami Maki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Metabolomics
- Research Institution
  National Center for Child Health and Development
Management and treatment for the behavioral symptom of Prader-Willi syndromePrincipal Investigator
- Principal Investigator
  
  Ayabe Tadayuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Pediatrics
- Research Institution
  National Center for Child Health and Development
Genetic and environmental factors involved in human genomic instability
- Principal Investigator
  
  FUKAMI maki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Human genetics
- Research Institution
  National Research Institute for Child Health and Development

All 2018 2017 2016 2015 2013 Other

All Journal Article Presentation Other

[Journal Article] Delayed peak response of cortisol to insulin tolerance test in patients with Prader-Willi syndrome2018
- Author(s)
  Yuji Oto, Keiko Matsubara, Tadayuki Ayabe, Masahisa Shiraishi, Nobuyuki Murakami, Hiroshi Ihara, Tomoyo Matsubara, Toshiro Nagai.
- Journal Title
  
  American Journal of Medical Genetics part A
  
  Volume: 印刷中 Issue: 6 Pages: 1369-1374
- DOI
  10.1002/ajmg.a.38713
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19630
[Journal Article] Protein-altering variants of PTPN2 in childhood-onset Type 1A diabetes2018
- Author(s)
  Okuno M.、Ayabe T.、Yokota I.、Musha I.、Shiga K.、Kikuchi T.、Kikuchi N.、Ohtake A.、Nakamura A.、Nakabayashi K.、Okamura K.、Momozawa Y.、Kubo M.、Suzuki J.、Urakami T.、Kawamura T.、Amemiya S.、Ogata T.、Sugihara S.、Fukami M.、the Japanese Study Group of Insulin Therapy for Childhood and Adolescent Diabetes
- Journal Title
  
  Diabetic Medicine
  
  Volume: 35 Issue: 3 Pages: 376-380
- DOI
  10.1111/dme.13566
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07137, KAKENHI-PROJECT-16K15491, KAKENHI-PROJECT-17H04204
[Journal Article] Aberrant autistic, and food-related behaviors in adults with Prader-Willi syndrome: The comparison between young adults and adults.2018
- Author(s)
  Hiroyuki Ogata, Hiroshi Ihara, Masao Gito, Masayuki Sayama, Nobuyuki Murakami, Tadayuki Ayabe, Yuji Oto, Toshiro Nagai, Kazutaka Shimoda.
- Journal Title
  
  Research in Development Disabilities
  
  Volume: 73 Pages: 126-134
- DOI
  10.1016/j.ridd.2017.12.020
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19630
[Journal Article] Comprehensive screening for monogenic diabetes in 89 Japanese children with insulin-requiring antibody-negative type 1 diabetes2017
- Author(s)
  Ushijima K, Fukami M, Ayabe T, Narumi S, Okuno M, Nakamura A, Takahashi T, Ihara K, Ohkubo K, Tachikawa E, Nakayama S, Arai J, Kikuchi N, Kikuchi T, Kawamura T, Urakami T, Hata K, Nakabayashi K, Matsubara Y, Amemiya S, Ogata T, Yokota I, Sugihara S
- Journal Title
  
  Pediatric Diabetes
  
  Volume: 19 Issue: 2 Pages: 243-250
- DOI
  10.1111/pedi.12544
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15491, KAKENHI-PROJECT-17H04204
[Journal Article] Autistic, Aberrant, and Food-Related Behaviors in Adolescents and Young Adults with Prader-Willi Syndrome: The Effects of Age and Genotype2017
- Author(s)
  Atsuhi Ishii, Hiroshi Ihara, Hiroyuki Ogata, Masayuki Sayama, Masao Gito, Nobuyuki Murakami, Tadayuki Ayabe, Yuji Oto, Asami Takahashi, Toshiro Nagai.
- Journal Title
  
  Behavioural Neurology
  
  Volume: － Pages: 1-10
- DOI
  10.1155/2017/4615451
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19630
[Journal Article] Nucleotide substitutions in CD101, the human homolog of a diabetes susceptibility gene in non-obese diabetic mouse, in patients with type 1 diabetes.2017
- Author(s)
  Okuno M, Kasahara Y, Onodera M, Takubo N, Okajima M, Suga S, Watanabe N, Suzuki J, Ayabe T, Urakami T, Kawamura T, Kikuchi N, Yokota I, Kikuchi T, Amemiya S, Nakabayashi K, Hayashi K, Hata K, Matsubara Y, Ogata T, Fukami M, Sugihara S
- Journal Title
  
  J Diabetes Investig.
  
  Volume: 印刷中 Issue: 3 Pages: 286-294
- DOI
  10.1111/jdi.12586
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15491
[Journal Article] プラダー・ウィリ症候群をもつ子ども達への関わり方2016
- Author(s)
  綾部匡之, 永井敏郎
- Journal Title
  
  小児保健研究
  
  Volume: 75 Pages: 312-317
- Data Source
  KAKENHI-PROJECT-15K19630
[Journal Article] Decline of CSF Orexin (Hypocretin) Levels in Prader-Willi Syndrome.2016
- Author(s)
  Mayu Omokawa, Tadayuki Ayabe, Toshiro Nagai, Aya Imanishi, Ayumi Omokawa, Seiji Nishino, Yohei Sagawa, Tetsuo Shimizu, Takashi Kanbayashi.
- Journal Title
  
  American Journal of Medical Genetics part A
  
  Volume: 170 Issue: 5 Pages: 1181-1186
- DOI
  10.1002/ajmg.a.37542
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19630, KAKENHI-PROJECT-15K09821, KAKENHI-PROJECT-16K10203
[Journal Article] プラダー・ウィリ症候群をもつ子ども達への関わり方2016
- Author(s)
  綾部匡之, 永井敏郎.
- Journal Title
  
  小児保健研究
  
  Volume: 74
- Data Source
  KAKENHI-PROJECT-15K19630
[Journal Article] Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.2013
- Author(s)
  Matsumura T, Imamichi Y, Mizutani T, Ju Y, Yazawa T, Kawabe S, Kanno M, Ayabe T, Katsumata N, Fukami M, Inatani M, Akagi Y, Umezawa A, Ogata T, Miyamoto K
- Journal Title
  
  FASEB J
  
  Volume: 27 Issue: 8 Pages: 3198-3208
- DOI
  10.1096/fj.12-222745
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22132004, KAKENHI-PROJECT-22227002, KAKENHI-PROJECT-23390249, KAKENHI-PROJECT-23590329, KAKENHI-PROJECT-23591523, KAKENHI-PROJECT-24390395, KAKENHI-PROJECT-24590347, KAKENHI-PROJECT-25253023, KAKENHI-PROJECT-25670173, KAKENHI-PROJECT-25670440, KAKENHI-PROJECT-25861481, KAKENHI-PROJECT-25861482
[Presentation] 糖尿病を合併したプラダー・ウィリ症候群患者に対するトホグリフロジンの長期使用経験2017
- Author(s)
  綾部匡之, 大戸佑二, 村上信行, 永井敏郎
- Organizer
  第60回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-15K19630
[Presentation] 1B型糖尿病発症における単一遺伝子変異の寄与の解明2017
- Author(s)
  牛嶋規久美, 深見真紀, 綾部匡之, 奥野美佐子, 鳴海覚志, 緒方勤, 菊池信行, 菊池透, 川村智行, 浦上達彦, 横田一郎, 雨宮伸, 杉原茂孝
- Organizer
  第90回日本内分泌学会学術集会
- Data Source
  KAKENHI-PROJECT-16K15491
[Presentation] 小児・思春期糖尿病治療のさらなる課題：プラダー・ウィリ症候群に伴う糖尿病の管理のコツ2016
- Author(s)
  綾部匡之
- Organizer
  第22回日本小児・思春期糖尿病研究会年次学術集会
- Place of Presentation
  大阪
- Year and Date
  2016-07-10
- Data Source
  KAKENHI-PROJECT-15K19630
[Presentation] プラダー・ウィリ症候群患者の日中過眠は視床下部のオレキシン機能低下が原因である2016
- Author(s)
  綾部匡之, 大戸佑二, 村上信行, 松原知代, 永井敏郎
- Organizer
  第119回日本小児科学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15K19630
[Presentation] ucleotide substitutions in CD101, the human homolog of diabetes mellitus susceptibility gene in non-obese diabetic mouse, in patients with type 1 diabetes mellitus.2016
- Author(s)
  Okuno M, Kasahara Y, Takubo N, Okajima M, Suga S, Suzuki J, Ayabe T, Urakami T, Kawamura T, Kikuchi N, Yokota I, Kikuchi T, Amemiya S, Ogata T, Fukami M, Sugihara S.
- Organizer
  42th Annual Conference of the International Society for Pediatrics and Adolescent Diabetes
- Place of Presentation
  Spain
- Year and Date
  2016-10-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15491
[Presentation] 糖尿病管理のコツ2016
- Author(s)
  綾部匡之
- Organizer
  Meet The Specialists Prader-Willi syndrome
- Place of Presentation
  東京
- Year and Date
  2016-09-25
- Invited
- Data Source
  KAKENHI-PROJECT-15K19630
[Presentation] Nucleotide substitutions in CD101, the human homolog of diabetes mellitus susceptibility gene in non-obese diabetic mouse, in patients with type 1 diabetes mellitus2016
- Author(s)
  Okuno M, Kasahara Y, Takubo N, Okajima M, Suga S, Suzuki J, Ayabe T, Urakami T, Kawamura T, Kikuchi N, Yokota I, Kikuchi T, Amemiya S, Ogata T, Fukami M, Sugihara S
- Organizer
  The 9th Biennial Scientific Meeting of the Asia Pacific Paediatric Endocrine Society
- Place of Presentation
  東京
- Year and Date
  2016-11-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15491
[Presentation] Reduced cerebrospinal fluid orexin in Prader-Willi syndrome patients2016
- Author(s)
  Tadayuki Ayabe Mayu Omokawa, Yuji Oto, Maki Fukami, Nobuyuki Murakami, Takashi Kanbayashi, Toshiro Nagai.
- Organizer
  2016 International Prader-Willi Syndrome Organisation Conference
- Place of Presentation
  Toronto, Canada
- Year and Date
  2016-07-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19630
[Presentation] Next-generation sequencing-based comprehensive mutation screening in 89 Japanese children clinically diagnosed with type 1B diabetes2016
- Author(s)
  Ushijima K, Fukami M, Ayabe T, Okuno M, Narumi S, Ogata T, Kikuchi N, Kikuchi T, Kawamura T, Urakami T, Yokota I, Amemiya S, Sugihara S
- Organizer
  The 9th Biennial Scientific Meeting of the Asia Pacific Paediatric Endocrine Society
- Place of Presentation
  東京
- Year and Date
  2016-11-18
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15491
[Presentation] 日中過眠とオレキシン2015
- Author(s)
  綾部匡之
- Organizer
  Meet The Specialists Prader-Willi syndrome
- Place of Presentation
  東京
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K19630
[Presentation] プラダー・ウィリ症候群とお昼寝の話2015
- Author(s)
  綾部匡之
- Organizer
  第10回PWSもこもこの会（患者会）
- Place of Presentation
  大阪
- Year and Date
  2015-12-19
- Invited
- Data Source
  KAKENHI-PROJECT-15K19630
[Presentation] 髄液オレキシン低値は、プラダー・ウィリ症候群患者の日中過眠の要因か？2015
- Author(s)
  綾部匡之, 面川真由, 大戸佑二, 村上信行, 神林崇, 永井敏郎
- Organizer
  第49回日本小児内分泌学会学術集会
- Place of Presentation
  東京
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-15K19630
[]

1. FUKAMI maki (40265872)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
2. IGARASHI Maki (10623035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. KANBAYASHI Takashi (50323150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. NAGAI Toshiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 10 results
5. IHARA Hiroshi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. OMOKAWA Mayu

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
7. OKUNO MISAKO

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
8. USHIJIMA KIKUMI

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. OGATA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 岡村浩司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

AYABE Tadayuki 綾部 匡之

Research Projects

Research Products

Co-Researchers

Clarification of molecular basis of type 1 diabetes using novel technologies

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Management and treatment for the behavioral symptom of Prader-Willi syndromePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Genetic and environmental factors involved in human genomic instability

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Delayed peak response of cortisol to insulin tolerance test in patients with Prader-Willi syndrome2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protein-altering variants of PTPN2 in childhood-onset Type 1A diabetes2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Aberrant autistic, and food-related behaviors in adults with Prader-Willi syndrome: The comparison between young adults and adults.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comprehensive screening for monogenic diabetes in 89 Japanese children with insulin-requiring antibody-negative type 1 diabetes2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Autistic, Aberrant, and Food-Related Behaviors in Adolescents and Young Adults with Prader-Willi Syndrome: The Effects of Age and Genotype2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleotide substitutions in CD101, the human homolog of a diabetes susceptibility gene in non-obese diabetic mouse, in patients with type 1 diabetes.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] プラダー・ウィリ症候群をもつ子ども達への関わり方2016

Author(s)

Journal Title

Data Source

[Journal Article] Decline of CSF Orexin (Hypocretin) Levels in Prader-Willi Syndrome.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] プラダー・ウィリ症候群をもつ子ども達への関わり方2016

Author(s)

Journal Title

Data Source

[Journal Article] Human glutathione S-transferase A (GSTA) family genes are regulated by steroidogenic factor 1 (SF-1) and are involved in steroidogenesis.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 糖尿病を合併したプラダー・ウィリ症候群患者に対するトホグリフロジンの長期使用経験2017

Author(s)

Organizer

Data Source

[Presentation] 1B型糖尿病発症における単一遺伝子変異の寄与の解明2017

Author(s)

Organizer

Data Source

[Presentation] 小児・思春期糖尿病治療のさらなる課題：プラダー・ウィリ症候群に伴う糖尿病の管理のコツ2016

Author(s)

AYABE Tadayuki 綾部匡之