Kinisada Makoto 国定充

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Kunisada Makoto 国定充

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Researcher Number	80566969
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学研究科, 医学研究員
Affiliation (based on the past Project Information) *help	2023 – 2024: 神戸大学, 医学研究科, 非常勤講師 2022: 神戸大学, 医学研究科, 准教授 2021: 神戸大学, 医学部附属病院, 講師 2020: 神戸大学, 医学部附属病院, 病院准教授 2016 – 2019: 神戸大学, 医学部附属病院, 講師 2013 – 2015: 神戸大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Basic Section 50010:Tumor biology-related
Keywords	Principal Investigator 紫外線皮膚発癌 / 炎症 / 紫外線皮膚発がん / 色素性乾皮症 / 紫外線発癌 / 炎症反応 / 活性酸素 / DNA損傷 / 全エクソーム解析 / 次世代シーケンサー … More / Xpa-ノックアウトマウス / 多段階発がん / 紫外線 / DNA傷害 / ボリコナゾール / サイトカイン / Xpaノックアウトマウス / CXCL1 / UVB / p53 / スピルリナ / Ogg1マウス / 紫外線発がん … More Except Principal Investigator 空間的増殖 / 変異クローン / 体細胞変異 / がん関連遺伝子 / 正常組織 Less

Gene-environment interactions inducing spatial expansion of mutant clones in human normal tissues
- Principal Investigator
  
  中岡博史
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 50010:Tumor biology-related
- Research Institution
  Sasaki Foundation
The landscape of genetic alterations of UVB-induced skin tumors in DNA repair-deficient micePrincipal Investigator
- Principal Investigator
  
  Kunisada Makoto
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Kobe University
The study of the elements of inflammatory response related with ultraviolet-induced skin carcinogenesis using Xpa knockout mice-the control of inflammation in the skinPrincipal Investigator
- Principal Investigator
  
  KUNISADA MAKOTO
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University
Mechanism of photo-skin-carcinogenesis induced by ultraviolet/reactive oxygen species/DNA damage; how associated with inflammatory response?Principal Investigator
- Principal Investigator
  
  Kunisada Makoto
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Kobe University

All 2023 2022 2018 2017 2015 2014 2013 Other

All Journal Article Presentation

[Journal Article] The landscape of genetic alterations of <scp>UVB</scp> ‐induced skin tumors in <scp>DNA</scp> repair‐deficient mice2022
- Author(s)
  Yoshioka Ai、Nakaoka Hirofumi、Fukumoto Takeshi、Inoue Ituro、Nishigori Chikako、Kunisada Makoto
- Journal Title
  
  Experimental Dermatology
  
  Volume: 31 Issue: 10 Pages: 1607-1617
- DOI
  10.1111/exd.14634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08749
[Journal Article] Inflammation Due to Voriconazole-induced Photosensitivity Enhanced Skin Phototumorigenesis in Xpa-knockout Mice2018
- Author(s)
  Kunisada M, Yamano N, Hosaka C, Takemori C, Nishigori C
- Journal Title
  
  Photochem Photobiol
  
  Volume: 94 Issue: 5 Pages: 1077-1081
- DOI
  10.1111/php.12972
- NAID
  120006709580
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10126
[Journal Article] Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis.2017
- Author(s)
  Takemori C, Kunisada M, Yogianti F, Oka S, Sakumi K, Ono R, Nakabeppu Y, Nishigori C.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 85 Issue: 2 Pages: 140-143
- DOI
  10.1016/j.jdermsci.2016.10.011
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10126, KAKENHI-PROJECT-17K19913, KAKENHI-PROJECT-15H04298
[Journal Article] CXCL1 inhibition regulates UVB-induced skin inflammation and tumorigenesis in Xpa-deficient mice.2017
- Author(s)
  Kunisada M, Hosaka C, Takemori C, Nakano E, Nishigori C.
- Journal Title
  
  J Invest Dermatol
  
  Volume: 137 Issue: 9 Pages: 1975-83
- DOI
  10.1016/j.jid.2017.04.034
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10126
[Journal Article] Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics2015
- Author(s)
  Goto N, Bazar C, Kovacs Z, Kunisada M, Morita H, Kizaki S, Sugiyama H, Tsenkova R, Nishigori C
- Journal Title
  
  Sci Rep
  
  Volume: Jul 2;5 Issue: 1 Pages: 11808-11808
- DOI
  10.1038/srep11808
- NAID
  120005822771
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25461668, KAKENHI-PROJECT-25292156
[Journal Article] Inhibitory effects of dietary Spirulina platensis on UVB-induced skin inflammatory responses and carcinogenesis2014
- Author(s)
  Yogianti F, Kunisada M, Nakano E, Ono R, Sakumi K, Oka S, Nakabeppu Y, Nishigori C
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 00
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461668
[Journal Article] Inhibitory effects of dietary Spirulina platensis on UVB induced skin inflammatory responses and carcinogenesis.2014
- Author(s)
  Yogianti, F., Kunisada, M., Nakano, E., Ono, R., Sakumi, K., Oka, S., Nakabeppu, Y., and Nishigori, C.
- Journal Title
  
  J Invest Dermatol
  
  Volume: N/A Issue: 10 Pages: 2610-2619
- DOI
  10.1038/jid.2014.188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PROJECT-25461281, KAKENHI-PROJECT-25461668
[Presentation] DNA修復機構欠損マウスでUVB照射により形成された皮膚腫瘍の網羅的遺伝子変異解析2023
- Author(s)
  国定　充,吉岡愛育, 中岡博史, 福本毅, 久保　亮治, 井ノ上逸朗, 錦織千佳子
- Organizer
  第45回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-19K08749
[Presentation] Voriconazole enhances skin tumor development through induction of inflammation caused by ultraviolet B2018
- Author(s)
  Makoto Kunisada, Chieko Hosaka, Chihiro Takemori, Eiji Nakano, Chikako Nishigori
- Organizer
  World Congress of Cancers of the Skin
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10126
[Presentation] Voriconazole enhances skin tumor development through induction of inflammation caused by ultraviolet B2018
- Author(s)
  Makoto Kunisada, Chieko Hosaka, Chihiro Takemori, Eiji Nakano, Chikako Nishigori
- Organizer
  International Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10126
[Presentation] ボリコナゾールによる光毒性反応による炎症増強反応はXpaノックアウトマウスにおいて皮膚腫瘍を増加させる2018
- Author(s)
  国定充、山野希、保坂千恵子、竹森千尋、錦織千佳子
- Organizer
  第40回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-16K10126
[Presentation] CXCL1抗体はXpa欠損マウスにおけるUVB誘導の皮膚の炎症反応および皮膚腫瘍発生を抑制する2017
- Author(s)
  国定充、保坂千恵子、竹森千尋、中野英司、榎本秀樹、錦織千佳子
- Organizer
  第39回日本光医学・光生物学会
- Data Source
  KAKENHI-PROJECT-16K10126
[Presentation] CXCL1 inhibition regulates UVB-induced skin inflammation and tumorigenesis in Xpa deficient mice2017
- Author(s)
  Makoto Kunisada, Chieko Hosaka, Chihiro Takemori, Eiji Nakano, Chikako Nishigori
- Organizer
  The 42th Annual meetings of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10126
[Presentation] （奨励賞講演）Spirulina platensisにおける抗炎症反応を介してのUVB長期照射によるマウス皮膚発癌抑制作用の検討2014
- Author(s)
  国定　充、Flandiana Yogianti、小野竜介、作見邦彦、岡素雅子、中別府雄作、錦織千佳子
- Organizer
  第36回日本光医学・光生物学会
- Place of Presentation
  大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25461668
[Presentation] Molecular mechanisms of UVB carcinogenesis2014
- Author(s)
  国定　充
- Organizer
  World Congress of Cancers of the Skin at the Edinburgh
- Place of Presentation
  エジンバラ
- Invited
- Data Source
  KAKENHI-PROJECT-25461668
[Presentation] Spirulina platensisにおける抗炎症反応を介してのUVB長期照射によるマウス皮膚発癌抑制作用の検討2013
- Author(s)
  国定　充、Flandiana Yogianti、小野竜介、作見邦彦、岡素雅子、中別府雄作、錦織千佳子
- Organizer
  第35回日本光医学・光生物学会
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-25461668
[Presentation] Molecular mechanisms of UVB carcinogenesis
- Author(s)
  Makoto Kunisada
- Organizer
  XV WORLD CONGRESS ON CANCERS OF THE SKIN
- Place of Presentation
  エジンバラ、英国
- Year and Date
  2014-09-03 – 2014-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-25461668
[Presentation] Spirulina platensisにおける抗炎症反応を介してのUVB長期照射によるマウス皮膚発癌抑制作用の検討
- Author(s)
  国定　充
- Organizer
  日本光医学・光生物学会
- Place of Presentation
  浜松市
- Year and Date
  2014-07-25 – 2014-07-26
- Invited
- Data Source
  KAKENHI-PROJECT-25461668

1. 中岡博史 (70611193)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 椙村春彦 (00196742)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 吉原弘祐 (40547535)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 須田一暁 (80650621)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 福本毅 (80778770)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 後藤明輝 (90317090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OKA Sugako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 作見邦彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中別府雄作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kinisada Makoto 国定 充

Kunisada Makoto 国定 充

Research Projects

Research Products

Co-Researchers

Gene-environment interactions inducing spatial expansion of mutant clones in human normal tissues

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The landscape of genetic alterations of UVB-induced skin tumors in DNA repair-deficient micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The study of the elements of inflammatory response related with ultraviolet-induced skin carcinogenesis using Xpa knockout mice-the control of inflammation in the skinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of photo-skin-carcinogenesis induced by ultraviolet/reactive oxygen species/DNA damage; how associated with inflammatory response?Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The landscape of genetic alterations of <scp>UVB</scp> ‐induced skin tumors in <scp>DNA</scp> repair‐deficient mice2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inflammation Due to Voriconazole-induced Photosensitivity Enhanced Skin Phototumorigenesis in Xpa-knockout Mice2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Co-regulation of Cxcl1 and versican in the inflammatory response to UVB induced reactive oxygen species in skin photo-tumorigenesis.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] CXCL1 inhibition regulates UVB-induced skin inflammation and tumorigenesis in Xpa-deficient mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Detection of UV-induced cyclobutane pyrimidine dimers by near-infrared spectroscopy and aquaphotomics2015

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Inhibitory effects of dietary Spirulina platensis on UVB-induced skin inflammatory responses and carcinogenesis2014

Author(s)

Journal Title

Data Source

[Journal Article] Inhibitory effects of dietary Spirulina platensis on UVB induced skin inflammatory responses and carcinogenesis.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] DNA修復機構欠損マウスでUVB照射により形成された皮膚腫瘍の網羅的遺伝子変異解析2023

Author(s)

Organizer

Data Source

[Presentation] Voriconazole enhances skin tumor development through induction of inflammation caused by ultraviolet B2018

Author(s)

Organizer

Data Source

[Presentation] Voriconazole enhances skin tumor development through induction of inflammation caused by ultraviolet B2018

Author(s)

Organizer

Data Source

[Presentation] ボリコナゾールによる光毒性反応による炎症増強反応はXpaノックアウトマウスにおいて皮膚腫瘍を増加させる2018

Author(s)

Organizer

Kinisada Makoto 国定充

Kunisada Makoto 国定充