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OTSUBO Ryota  大坪 竜太

ORCIDConnect your ORCID iD *help
Researcher Number 80570043
Other IDs
Affiliation (Current) 2025: 長崎大学, 病院(医学系), 教授
Affiliation (based on the past Project Information) *help 2025: 長崎大学, 病院(医学系), 准教授
2023: 長崎大学, 病院(医学系), 准教授
2020 – 2023: 長崎大学, 病院(医学系), 講師
2015 – 2019: 長崎大学, 病院(医学系), 助教
2014: 長崎大学, 産学官連携戦略本部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / General surgery
Except Principal Investigator
Basic Section 55010:General surgery and pediatric surgery-related / General surgery
Keywords
Principal Investigator
乳癌 / リンパ節転移 / サイトケラチン / 術前薬物療法 / Semi-dry dot-blot / Image-guided surgery / 蛍光色素 / 近赤外線 / HER2陽性 / image-guided surgery … More / 癌 / 甲状腺 / 病理学 / Semi-dry dot-blot法 / 甲状腺乳頭癌 … More
Except Principal Investigator
mutation analysis / copy number anlaysis / copy number analysis / 次世代シークエンス / トランスレーショナルリサーチ / リキッドバイオプシー / 乳がん / 次世代シークエンサー / Liquid Biopsy / circulating tumor DNA / 乳癌 / 甲状腺濾胞癌 / 核内フォーカス / p53 binding protein 1 / 術前診断 / 濾胞癌 / 53BP1核内フォーカス / 術前細胞診診断 / 甲状腺濾胞性腫瘍 Less
  • Research Projects

    (6 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (8 People)
  •  新規乳癌リンパ節転移診断キットの術前薬物療法症例における臨床性能試験Principal Investigator

    • Principal Investigator
      大坪 竜太
    • Project Period (FY)
      2025 – 2029
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nagasaki University
  •  Expanding of indication about the new diagnostic kit to detect lymph node metastases for breast cancer patients with preoperative systemic therapyPrincipal Investigator

    • Principal Investigator
      大坪 竜太
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nagasaki University
  •  Exploration of Novel Diagnostic and Therapeutic Approaches for Breast Cancer Using an Innovative Liquid Biopsy Method

    • Principal Investigator
      OIKAWA Masahiro
    • Project Period (FY)
      2019 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nagasaki University
  •  Tracer search in image-guided surgery of HER2-positive breast cancerPrincipal Investigator

    • Principal Investigator
      Otsubo Ryota
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 55010:General surgery and pediatric surgery-related
    • Research Institution
      Nagasaki University
  •  Development of a novel diagnostic kit to detect lymph nodes in thyroid papillary carcinomaPrincipal Investigator

    • Principal Investigator
      OTSUBO Ryota
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagasaki University
  •  Immunofluorescence analysis of P53-binding protein 1 in thyroid follicular tumours

    • Principal Investigator
      YANO Hiroshi
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      General surgery
    • Research Institution
      Nagasaki University

All 2024 2021 2019 2018 2017 2016 2014

All Journal Article Presentation

  • [Journal Article] Protocol for studying the efficiency of ChemoCalc software in helping patients to understand drug treatment costs for breast cancer: A multicenter, open-label, randomized phase 2 study2021

    • Author(s)
      Kuba Sayaka、Moriuchi Hiroki、Yamanouchi Kosho、Shibata Kenichiro、Yano Hiroshi、Oikawa Masahiro、Maeda Shigeto、Meng Xiangyue、Morita Michi、Hatachi Toshiko、Otsubo Ryota、Matsumoto Megumi、Miyamoto Junya、Kanetaka Kengo、Taniguchi Hideki、Nagayasu Takeshi、Eguchi Susumu
    • Journal Title

      Contemporary Clinical Trials Communications

      Volume: 21 Pages: 100739-100739

    • DOI

      10.1016/j.conctc.2021.100739

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K09075
  • [Journal Article] A novel diagnostic method for thyroid follicular tumors based on immunofluorescence analysis of p53-binding protein 1 expression: detection of genomic instability2019

    • Author(s)
      Otsubo Ryota、Matsuda Katsuya、Mussazhanova Zhanna、Sato Ayako、Matsumoto Megumi、Yano Hiroshi、Oikawa Masahiro、Kondo Hisayoshi、Ito Masahiro、Miyauchi Akira、Hirokawa Mitsuyoshi、Nagayasu Takeshi、Nakashima Masahiro
    • Journal Title

      Thyroid

      Volume: 印刷中 Issue: 5 Pages: 657-665

    • DOI

      10.1089/thy.2018.0548

    • NAID

      120006987702

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16KK0204, KAKENHI-PROJECT-19K07471, KAKENHI-PROJECT-19K09075
  • [Journal Article] Validation of a Novel Diagnostic Kit Using the Semidry Dot-Blot Method to Detect Metastatic Lymph Nodes in Breast Cancer: Distinguishing Macrometastases From Nonmacrometastases.2018

    • Author(s)
      Ryota Otsubo
    • Journal Title

      Clinical Breast Cancer

      Volume: 18

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10461
  • [Journal Article] Validation of a Novel Diagnostic Kit Using the Semidry Dot-Blot Method to Detect Metastatic Lymph Nodes in Breast Cancer: Distinguishing Macrometastases From Nonmacrometastases.2017

    • Author(s)
      Ryota Otsubo
    • Journal Title

      Clinical breast cancer

      Volume: 17 Issue: 3 Pages: e345-e351

    • DOI

      10.1016/j.clbc.2017.07.009

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16K10461, KAKENHI-PROJECT-16KK0204, KAKENHI-PROJECT-15K19865
  • [Presentation] Semi-dry dot-blot(SDB)法を応用した新規乳癌リンパ節転移診断キットの術前薬物療法症例への適応拡大2024

    • Author(s)
      大坪 竜太
    • Organizer
      第124回 日本外科学会定期学術集会(サージカルフォーラム)
    • Data Source
      KAKENHI-PROJECT-22K08695
  • [Presentation] Unbiased copy number analysis of circulating tumor DNA among HER2-positive breast cancer patients2019

    • Author(s)
      Masahiro Oikawa, Yasuko Enomoto, Kazuhumi Hisamatsu, Tetsuo Hamada, Ryota Otsubo, Hiroshi Yano, Takeshi Nagayasu, Hiroyuki Mishima, Koh-ichiro Yoshiura and Nicholas Navin
    • Organizer
      2019 San Antonio Breast Cancer Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K09075
  • [Presentation] PEGASUS (Plasma Exome and Genome Analysis by Size-Selection and Unbiased Sequencing) を用いた乳癌のリキッドバイオプシー研究2019

    • Author(s)
      及川将弘、榎本康子、久松和史、及川達司、濵田哲夫、大坪竜太、矢野洋、永安武、Nicholas E Navin
    • Organizer
      2019年度日本乳癌学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K09075
  • [Presentation] 乳癌患者における血漿遊離DNA (cfDNA)濃度と血漿循環腫瘍DNA (ctDNA)の解析2019

    • Author(s)
      及川将弘、瀬戸口優美香、榎本康子、久松和史、及川達司、濵田哲夫、大坪竜太、松本恵、矢野洋、永安武、三嶋博之、木下晃、吉浦孝一郎
    • Organizer
      2019年度日本人追遺伝学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K09075
  • [Presentation] Validation of novel diagnostic kits using the semi-dry dot-blot method for detecting metastatic lymph nodes in breast cancer; distinguishing macrometastases and micrometastases2016

    • Author(s)
      Ryota Otsubo
    • Organizer
      San Antonio Breast Cancer Symposium 2016
    • Place of Presentation
      San Antonio, Texas, USA
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10461
  • [Presentation] 甲状腺濾胞性腫瘍診断におけるp53 binding protein 1(53BP1)核内フォーカスとアレイCGH解析2014

    • Author(s)
      大坪 竜太
    • Organizer
      第47回 日本甲状腺外科学会学術集会
    • Place of Presentation
      アクロス福岡(福岡市)
    • Year and Date
      2014-10-30
    • Data Source
      KAKENHI-PROJECT-26461951
  • [Presentation] Immunofluorescence analysis of p53-binding protein 1 in thyroid follicular tumors: possibility for preoperative diagnosis2014

    • Author(s)
      大坪 竜太
    • Organizer
      European Congress of Pathology 2014
    • Place of Presentation
      ExCeL London(UK)
    • Year and Date
      2014-09-01
    • Data Source
      KAKENHI-PROJECT-26461951
  • 1.  永安 武 (80284686)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 2.  YANO Hiroshi (50380887)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 4 results
  • 3.  中島 正洋 (50284683)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  OIKAWA Masahiro (90612416)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  馬場 雅之 (90771957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  三嶋 博之 (10513319)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  田中 彩 (50893244)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  松本 恵 (90404269)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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