Morozumi Yuichi 両角佑一

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MOROZUMI Yuichi 両角佑一

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Researcher Number	80571439
Other IDs
Affiliation (Current)	2025: 奈良先端科学技術大学院大学, 先端科学技術研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 2018 – 2023: 奈良先端科学技術大学院大学, 先端科学技術研究科, 助教 2017: 奈良先端科学技術大学院大学, バイオサイエンス研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related / Basic Section 44010:Cell biology-related / Genetics/Chromosome dynamics
Keywords	Principal Investigator TORC1 / target of rapamycin / ラパマイシン / 分裂酵母 / mTORC1 / シグナル伝達経路 / ブロモドメインタンパク質 / クロマチン / ES細胞 / ヒストン修飾 / ATAD2 / ブロモドメイン

高温環境での細胞増殖を抑制するメカニズムの解明Principal Investigator
- Principal Investigator
  
  両角佑一
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Nara Institute of Science and Technology
細胞成長を司るmTORC1キナーゼ複合体の活性制御機構の解明Principal Investigator
- Principal Investigator
  
  両角佑一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Nara Institute of Science and Technology
Molecular basis of substrate phosphorylation by mTORC1Principal Investigator
- Principal Investigator
  
  Morozumi Yuichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Nara Institute of Science and Technology
Functional analysis of ATAD2 in mouse embryonic stem cellsPrincipal Investigator
- Principal Investigator
  
  MOROZUMI Yuichi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Genetics/Chromosome dynamics
- Research Institution
  Nara Institute of Science and Technology

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology2024
- Author(s)
  Morozumi Yuichi、Mahayot Fontip、Nakase Yukiko、Soong Jia Xin、Yamawaki Sayaka、Sofyantoro Fajar、Imabata Yuki、Oda Arisa H.、Tamura Miki、Kofuji Shunsuke、Akikusa Yutaka、Shibatani Ayu、Ohta Kunihiro、Shiozaki Kazuhiro
- Journal Title
  
  iScience
  
  Volume: 27 Issue: 1 Pages: 108777-108777
- DOI
  10.1016/j.isci.2023.108777
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06145
[Journal Article] Fission Yeast TORC1 Promotes Cell Proliferation through Sfp1, a Transcription Factor Involved in Ribosome Biogenesis2023
- Author(s)
  Tai Yen Teng、Fukuda Tomoyuki、Morozumi Yuichi、Hirai Hayato、Oda Arisa H.、Kamada Yoshiaki、Akikusa Yutaka、Kanki Tomotake、Ohta Kunihiro、Shiozaki Kazuhiro
- Journal Title
  
  Molecular and Cellular Biology
  
  Volume: 43 Issue: 12 Pages: 675-692
- DOI
  10.1080/10985549.2023.2282349
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K14175, KAKENHI-PROJECT-22K06145, KAKENHI-PROJECT-23K05679, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-23K23878
[Journal Article] Fission yeast TOR complex 1 phosphorylates Psk1 through an evolutionarily conserved interaction mediated by the TOS motif2021
- Author(s)
  Morozumi Yuichi、Hishinuma Ai、Furusawa Suguru、Sofyantoro Fajar、Tatebe Hisashi、Shiozaki Kazuhiro
- Journal Title
  
  Journal of Cell Science
  
  Volume: 134 Issue: 19 Pages: 1-9
- DOI
  10.1242/jcs.258865
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03224, KAKENHI-PROJECT-19K06564
[Journal Article] Conserved and Divergent Mechanisms That Control TORC1 in Yeasts and Mammals2021
- Author(s)
  Morozumi Yuichi、Shiozaki Kazuhiro
- Journal Title
  
  Genes
  
  Volume: 12 Issue: 1 Pages: 88-88
- DOI
  10.3390/genes12010088
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06564, KAKENHI-PROJECT-19H03224
[Journal Article] Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase2021
- Author(s)
  Fukuda Tomoyuki、Sofyantoro Fajar、Tai Yen Teng、Chia Kim Hou、Matsuda Takato、Murase Takaaki、Morozumi Yuichi、Tatebe Hisashi、Kanki Tomotake、Shiozaki Kazuhiro
- Journal Title
  
  eLife
  
  Volume: 10
- DOI
  10.7554/elife.60969
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06564, KAKENHI-PROJECT-20K06552, KAKENHI-PROJECT-19K22419, KAKENHI-PLANNED-19H05712, KAKENHI-PROJECT-19H03224
[Journal Article] Characterization of Post-Meiotic Male Grem Cell Genome Organization States2018
- Author(s)
  Govin J, Barral S, Morozumi Y, Hoghoughi N, Buchou T, Rousseaux S, Khochbin S
- Journal Title
  
  Methods Mol. Biol.
  
  Volume: 1832 Pages: 293-307
- DOI
  10.1007/978-1-4939-8663-7_16
- ISBN
  9781493986620, 9781493986637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H06870
[Journal Article] The mystery of histone disappearance during spermatogenesis2017
- Author(s)
  Barral S, Morozumi Y, Hoghoughi N, Rousseaux S, Khochbin S
- Journal Title
  
  mdecine/sciences (Paris)
  
  Volume: 33 Pages: 588-590
- Data Source
  KAKENHI-PROJECT-17H06870
[Journal Article] 精子の形成の際のヒストンH2A.L.2を介したクロマチンリモデリングの機構2017
- Author(s)
  両角　佑一, 胡桃坂　仁志, Saadi Khochbin
- Journal Title
  
  First Author's
  
  Volume: - Pages: 035
- DOI
  10.7875/first.author.2017.035
- Open Access
- Data Source
  KAKENHI-PROJECT-17H06870
[Presentation] Identification of mechanisms that restrict cell growth below temperatures detrimental to cellular physiology2023
- Author(s)
  Morozumi Yuichi
- Organizer
  Pombe talks
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06145
[Presentation] 高温環境における分裂酵母の新たな適応メカニズムの解明2023
- Author(s)
  中瀬由起子、柴谷愛由、小藤峻裕、今端佑樹、Fontip Mahayot、両角佑一、渡辺大輔、塩﨑一裕
- Organizer
  酵母遺伝学フォーラム第56回研究報告会
- Data Source
  KAKENHI-PROJECT-22K06145
[Presentation] TORC1 signaling negatively regulates the cellular growth of fission yeast at high temperatures2023
- Author(s)
  Morozumi Yuchi, Nakase Yukiko, Shiozaki Kazuhiro
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06145
[Presentation] Dri1-Rhs1複合体を介した分裂酵母の高温耐性制御メカニズムの解析2023
- Author(s)
  秋草裕、両角佑一、山口敦也、渡辺大輔、塩﨑一裕
- Organizer
  酵母遺伝学フォーラム第56回研究報告会
- Data Source
  KAKENHI-PROJECT-22K06145
[Presentation] Identification of fission yeast genes that restrict cellular growth below temperatures detrimental to cellular physiology2023
- Author(s)
  Morozumi Yuchi, Nakase Yukiko, Shiozaki Kazuhiro
- Organizer
  11th International Fission Yeast Meeting Pombe 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06145
[Presentation] 分裂酵母Hhp1キナーゼはTORC1の抑制因子として機能する2022
- Author(s)
  両角　佑一、Chu Minh Cuong、高木　博史、塩﨑　一裕
- Organizer
  酵母遺伝学フォーラム第55回研究報告会
- Data Source
  KAKENHI-PROJECT-22K06145
[Presentation] mip1変異株を用いた分裂酵母TORC1の新規制御因子の遺伝学的探索2022
- Author(s)
  蓬田健、両角佑一、木原諒也、中瀬由起子、高木博史、塩﨑一裕
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-22K06145
[Presentation] 分裂酵母Pib2はTORC1の活性化因子として機能する2022
- Author(s)
  両角　佑一、林　佑美、Chu Minh Cuong、Sofyantoro Fajar、高木　博史、塩﨑　一裕
- Organizer
  第45回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] 分裂酵母の高温耐性を制御する因子の遺伝学的探索2022
- Author(s)
  今端　佑樹、両角佑一、中瀬由起子、高木　博史、塩﨑一裕
- Organizer
  酵母遺伝学フォーラム第55回研究報告会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] TOSモチーフを介したTORC1の基質認識機構は分裂酵母においても保存されている2021
- Author(s)
  両角佑一, 塩﨑一裕
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] Isolation and characterization of novel fission yeast mutants with a decrease in TOR complex 1 activity2021
- Author(s)
  Cuong Chu, Yuichi Morozumi, Hiroshi Takagi, Kazuhiro Shiozaki
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] 分裂酵母TOR複合体2（TORC2）の制御サブユニットBit2の機能解析2021
- Author(s)
  趙鶴翔, Yuichi Morozumi, Hiroshi Takagi, Kazuhiro Shiozaki
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] Identification of the key proteins and pathway that regulate the ammonium transporter in fission yeast2021
- Author(s)
  Shet Lee Ng, Kazuhiro Shiozaki, Hiroshi Takagi, Yuichi Morozumi, Yukiko Nakase
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] S.pombeにおける疑似プロリントランスポーターPut4の同定2021
- Author(s)
  Yaoting Du, 中瀬由起子, 両角佑一, 高木博史, 塩﨑一裕
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] 分裂酵母mTORC1によるPol III転写抑制因子Maf1のリン酸化制御2019
- Author(s)
  伊計　舞、両角　佑一、塩﨑　一裕
- Organizer
  酵母遺伝学フォーラム第52回研究報告会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] 分裂酵母TORC1によるRNAポリメラーゼIII抑制因子Maf1の機能制御2019
- Author(s)
  両角　佑一、伊計　舞、塩﨑　一裕
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K06564
[Presentation] 分裂酵母TORC1の基質認識機構2018
- Author(s)
  両角　佑一、建部　恒、塩﨑　一裕
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-17H06870
[Presentation] The role of ATAD2 in mouse embryonic stem cells2017
- Author(s)
  両角　佑一, Faycal Boussouar, Minjia Tan, Apirate Chaikuad, Sandrine Curtet, Anne-Laure Vitte, Clotilde Rabatel, Alexandra Debernardi, Sophie Rousseaux, Matthieu Gerard, Stefan Knapp, Yingming Zhao, Saadi Khochbin.
- Organizer
  ConBio2017
- Data Source
  KAKENHI-PROJECT-17H06870

1. SHIOZAKI Kazuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 平井隼人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Morozumi Yuichi 両角 佑一

MOROZUMI Yuichi 両角 佑一

Research Projects

Research Products

Co-Researchers

高温環境での細胞増殖を抑制するメカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

細胞成長を司るmTORC1キナーゼ複合体の活性制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular basis of substrate phosphorylation by mTORC1Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of ATAD2 in mouse embryonic stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Rapamycin-sensitive mechanisms confine the growth of fission yeast below the temperatures detrimental to cell physiology2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fission Yeast TORC1 Promotes Cell Proliferation through Sfp1, a Transcription Factor Involved in Ribosome Biogenesis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fission yeast TOR complex 1 phosphorylates Psk1 through an evolutionarily conserved interaction mediated by the TOS motif2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Conserved and Divergent Mechanisms That Control TORC1 in Yeasts and Mammals2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of Post-Meiotic Male Grem Cell Genome Organization States2018

Author(s)

Journal Title

DOI

ISBN

Data Source

[Journal Article] The mystery of histone disappearance during spermatogenesis2017

Author(s)

Journal Title

Data Source

[Journal Article] 精子の形成の際のヒストンH2A.L.2を介したクロマチンリモデリングの機構2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Identification of mechanisms that restrict cell growth below temperatures detrimental to cellular physiology2023

Author(s)

Organizer

Data Source

[Presentation] 高温環境における分裂酵母の新たな 適応メカニズムの解明2023

Author(s)

Organizer

Data Source

[Presentation] TORC1 signaling negatively regulates the cellular growth of fission yeast at high temperatures2023

Author(s)

Organizer

Morozumi Yuichi 両角佑一

MOROZUMI Yuichi 両角佑一

[Presentation] 高温環境における分裂酵母の新たな適応メカニズムの解明2023