ono katsuhiko 小野勝彦

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Ono Katsuhiko 小野勝彦

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Researcher Number	80573592
Other IDs
Affiliation (Current)	2025: 熊本大学, 大学院生命科学研究部(医), 助教
Affiliation (based on the past Project Information) *help	2025: 熊本大学, 大学院生命科学研究部(医), 助教 2018 – 2023: 熊本大学, 大学院生命科学研究部(医), 助教 2018: 熊本大学, 大学院生命科学研究部, 助教 2016: 熊本大学, 大学院生命科学研究部(医), 助教 2015: 熊本大学, 生命科学研究部, 助教
Review Section/Research Field	Principal Investigator Basic Section 38030:Applied biochemistry-related / Bacteriology (including mycology) Except Principal Investigator Basic Section 37020:Chemistry and chemical methodology of biomolecules-related / Medium-sized Section 37:Biomolecular chemistry and related fields / Biomolecular chemistry and related fields
Keywords	Principal Investigator システイン / βラクタム / パースルフィド / 超硫黄 / 緑膿菌 / 超イオウ / チオール / 薬剤耐性 / ストレプトマイシン / βラクタム剤 … More / 抗菌剤 / システインパースルフィド / βラクタム系抗生物 / チオール化合物 / βラクタム系抗生物質 … More Except Principal Investigator システインパースルフィド / 活性イオウ / インフラマソーム / 自然炎症 / レドックス / 超硫黄分子 / NLRP3インフラマソーム / イオウ代謝 / 炎症 / 食作用 / マクロファージ / 細胞内殺菌 / 食細胞 / 安定同位体 / 酸化ストレス / メタボロミクス / 自然免疫 / 活性酸素 / グルタチオン Less

細菌における没食子酸誘導体の新規標的分子の探索Principal Investigator
- Principal Investigator
  
  小野勝彦
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Kumamoto University
超硫黄分子がもたらす細菌の新規薬剤耐性機構の解明Principal Investigator
- Principal Investigator
  
  小野勝彦
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38030:Applied biochemistry-related
- Research Institution
  Kumamoto University
Molecular mechanisms of inhibitory regulation of NLRP3 inflammasome by reactive sulfur species
- Principal Investigator
  
  Sawa Tomohiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kumamoto University
Mechanisms of intracellular bacterial killing induced by reactive sulfur species
- Principal Investigator
  
  Sawa Tomohiro
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 37:Biomolecular chemistry and related fields
- Research Institution
  Kumamoto University
Molecular mechanisms of NLRP3 inflammasome activation via glutathione efflux
- Principal Investigator
  
  Sawa Tomohiro
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 37020:Chemistry and chemical methodology of biomolecules-related
- Research Institution
  Kumamoto University
Reactive sulfur metabolomics for the study of cellular sulfur dynamics
- Principal Investigator
  
  Sawa Tomohiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomolecular chemistry and related fields
- Research Institution
  Kumamoto University
Study of the reaction between beta-lactam antibiotids and thiol compoundsPrincipal Investigator
- Principal Investigator
  
  Ono Katsuhiko
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Bacteriology (including mycology)
- Research Institution
  Kumamoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Styrene Maleic Acid Polymer-Encapsulated Chlorophyll as a Stable Micellar Nanoprobe for Advanced Anticancer Photodynamic Therapy2023
- Author(s)
  Islam Waliul、Tsutsuki Hiroyasu、Rahman Azizur、Harada Ayaka、Zhang Tianli、Ono Katsuhiko、Islam Rayhanul、Hossen Foysal、Niidome Takuro、Sawa Tomohiro、Fang Jun
- Journal Title
  
  ACS Applied Polymer Materials
  
  Volume: 5 Issue: 12 Pages: 10289-10302
- DOI
  10.1021/acsapm.3c02042
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05443, KAKENHI-PROJECT-22KF0311
[Journal Article] Alkyl gallates inhibit serine O-acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics2023
- Author(s)
  Toyomoto Touya、Ono Katsuhiko、Shiba Tomoo、Momitani Kenta、Zhang Tianli、Tsutsuki Hiroyasu、Ishikawa Takeshi、Hoso Kanae、Hamada Koma、Rahman Azizur、Wen Liping、Maeda Yosuke、Yamamoto Keiichi、Matsuoka Masao、Hanaoka Kenjiro、Niidome Takuro、Akaike Takaaki、Sawa Tomohiro
- Journal Title
  
  Frontiers in Microbiology
  
  Volume: 14 Pages: 1276447-1276447
- DOI
  10.3389/fmicb.2023.1276447
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K05443, KAKENHI-PROJECT-22K08602, KAKENHI-PROJECT-23K07942, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-ORGANIZER-21H05258, KAKENHI-PLANNED-21H05262, KAKENHI-PLANNED-21H05267, KAKENHI-PROJECT-21H02071, KAKENHI-PROJECT-23K25210, KAKENHI-PROJECT-23K27304
[Journal Article] Cystathionine γ-lyase self-inactivates by polysulfidation during cystine metabolism2023
- Author(s)
  Araki Shoma、Takata Tsuyoshi、Ono Katsuhiko、Sawa Tomohiro、Kasamatsu Shingo、Ihara Hideshi、Kumagai Yoshito、Akaike Takaaki、Watanabe Yasuo、Tsuchiya Yukihiro
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 24 Issue: 12 Pages: 9982-9982
- DOI
  10.3390/ijms24129982
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-23K20040, KAKENHI-PROJECT-22K05443, KAKENHI-PROJECT-22K06148, KAKENHI-PROJECT-23K06094, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-21H02071
[Journal Article] Structural Determination of the Nanocomplex of Borate with Styrene-Maleic Acid Copolymer-Conjugated Glucosamine Used as a Multifunctional Anticancer Drug2022
- Author(s)
  Waliul Islam,Hiroyasu Tsutsuki,Katsuhiko Ono,Ayaka Harada,Kozo Shinozaki,Takuro Niidome,Jun Fang,Tomohiro Sawa
- Journal Title
  
  ACS Applied Bio Materials
  
  Volume: 5 Pages: 5953-5964
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K05443
[Journal Article] Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection.2022
- Author(s)
  Tsutsuki Hiroyasu, Zhang Tianli, Yahiro Kinnosuke, Ono Katsuhiko, Fujiwara Yukio, Iyoda Sunao, Wei Fan-Yan, Monde Kazuaki, Seto Kazuko, Ohnishi Makoto, Oshiumi Hiroyuki, Akaike Takaaki, Sawa Tomohiro.
- Journal Title
  
  iScience
  
  Volume: 25 Issue: 4 Pages: 104050-104050
- DOI
  10.1016/j.isci.2022.104050
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K21496, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-19H03480, KAKENHI-PROJECT-20F20408, KAKENHI-PROJECT-20K07506, KAKENHI-PROJECT-20K08823, KAKENHI-PROJECT-22K05443, KAKENHI-PROJECT-22K19397, KAKENHI-PROJECT-17H06170
[Journal Article] ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation.2021
- Author(s)
  Zhang, T., Tsutsuki, H., Islam, W., Ono, K., Takeda, K., Akaike, T. and Sawa, T.
- Journal Title
  
  Redox Biology
  
  Volume: 41 Pages: 101930-101930
- DOI
  10.1016/j.redox.2021.101930
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07032, KAKENHI-PROJECT-20K08823, KAKENHI-PROJECT-20K21496, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-20F20408, KAKENHI-PROJECT-19K22258, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-18H05277
[Journal Article] Cysteine hydropersulfide inactivates β-lactam antibiotics to form ring opened carbothioic S-acids in bacteria.2021
- Author(s)
  Ono, K., Kitamura, Y., Zhang, T., Tsutsuki, H., Rahman, A., Akaike, T., Ihara, T., Sawa, T.
- Journal Title
  
  ACS Chem Biol.
  
  Volume: 16 Issue: 4 Pages: 731-739
- DOI
  10.1021/acschembio.1c00027
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22258, KAKENHI-PROJECT-19K22259, KAKENHI-PROJECT-20K21496, KAKENHI-PLANNED-21H05263, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-20H02769, KAKENHI-PROJECT-17H06170
[Journal Article] Involvement of protein disulfide isomerase in subtilase cytotoxin-induced cell death in HeLa cells2020
- Author(s)
  Tsutsuki Hiroyasu、Zhang Tianli、Harada Ayaka、Rahman Azizur、Ono Katsuhiko、Yahiro Kinnosuke、Niidome Takuro、Sawa Tomohiro
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 525 Issue: 4 Pages: 1068-1073
- DOI
  10.1016/j.bbrc.2020.03.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10019, KAKENHI-PROJECT-19K07534, KAKENHI-PROJECT-19K22258
[Journal Article] Enhanced Cellular Polysulfides Negatively Regulate TLR4 Signaling and Mitigate Lethal Endotoxin Shock2019
- Author(s)
  Zhang Tianli、Ono Katsuhiko、Tsutsuki Hiroyasu、Ihara Hideshi、Islam Waliul、Akaike Takaaki、Sawa Tomohiro
- Journal Title
  
  Cell Chemical Biology
  
  Volume: in press Issue: 5 Pages: 686-698.e4
- DOI
  10.1016/j.chembiol.2019.02.003
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K10019, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-19K22258, KAKENHI-PROJECT-17H06170, KAKENHI-PROJECT-18H02098
[Journal Article] Synthesis of Pegylated Manganese Protoporphyrin as a Catalase Mimic and Its Therapeutic Application to Acetaminophen-Induced Acute Liver Failure2019
- Author(s)
  Zhang Tianli、Fang Jun、Tsutsuki Hiroyasu、Ono Katsuhiko、Islam Waliul、Sawa Tomohiro
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 42 Issue: 7 Pages: 1199-1206
- DOI
  10.1248/bpb.b19-00152
- NAID
  130007672166
- ISSN
  0918-6158, 1347-5215
- Year and Date
  2019-07-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22258, KAKENHI-PROJECT-17K10019, KAKENHI-PROJECT-18H02098
[Journal Article] 細菌の硫化水素・RSSの代謝シグナル制御．2019
- Author(s)
  津々木博康、小野勝彦、澤　智裕．
- Journal Title
  
  細胞工学
  
  Volume: 34 Pages: 92-395
- Data Source
  KAKENHI-PROJECT-15H06509
[Journal Article] A Simple PLGA-AgNPL Film for Antibiofilm Formation by Contact Bactericidal Activity2018
- Author(s)
  Kyaw Kaung、Motoyama Nana、Ichimaru Hiroaki、Harada Ayaka、Morimura Shigeru、Ono Katsuhiko、Tsutsuki Hiroyasu、Sawa Tomohiro、Miyazawa Yuta、Mizoguchi Daigou、Niidome Takuro
- Journal Title
  
  Chemistry Letters
  
  Volume: 47 Issue: 3 Pages: 308-310
- DOI
  10.1246/cl.171022
- NAID
  130006434041
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-15H03115
[Journal Article] Reactive Cysteine Persulphides: Occurrence, Biosynthesis, Antioxidant Activity, Methodologies, and Bacterial Persulphide Signalling2018
- Author(s)
  Sawa Tomohiro、Ono Katsuhiko、Tsutsuki Hiroyasu、Zhang Tianli、Ida Tomoaki、Nishida Motohiro、Akaike Takaaki
- Journal Title
  
  Advances in Microbial Physiology
  
  Volume: 72 Pages: 1-28
- DOI
  10.1016/bs.ampbs.2018.01.002
- ISBN
  9780128144138
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-17K10019, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-16KT0013, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-18H05293
[Journal Article] Reactive Persulfides from Salmonella Typhimurium Downregulate Autophagy-Mediated Innate Immunity in Macrophages by Inhibiting Electrophilic Signaling2018
- Author(s)
  Khan Shahzada、Fujii Shigemoto、Matsunaga Tetsuro、Nishimura Akira、Ono Katsuhiko、Ida Tomoaki、Ahmed Khandaker Ahtesham、Okamoto Tatsuya、Tsutsuki Hiroyasu、Sawa Tomohiro、Akaike Takaaki
- Journal Title
  
  Cell Chemical Biology
  
  Volume: 25 Issue: 11 Pages: 1403-1413
- DOI
  10.1016/j.chembiol.2018.08.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08619, KAKENHI-PROJECT-17K10019, KAKENHI-PROJECT-18K07099, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-18H05277, KAKENHI-PROJECT-18H02098, KAKENHI-PROJECT-17K19205, KAKENHI-PROJECT-17K15408, KAKENHI-PROJECT-17H06170
[Journal Article] Synthesis and Characterization of 8-Nitroguanosine 3′,5′-Cyclic Monophosphorothioate Rp-Isomer as a Potent Inhibitor of Protein Kinase G1α2017
- Author(s)
  Ahmed KA, Zhang T, Ono K, Tsutsuki H, Ida T, Akashi S, Miyata K, Oike Y, Akaike T, Sawa T.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 40 Issue: 3 Pages: 365-374
- DOI
  10.1248/bpb.b16-00880
- NAID
  130005398514
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-14J05470, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20876
[Journal Article] Synthesis of L-cysteine derivatives containing stable sulfur isotopes and application of this synthesis to reactive sulfur metabolome2017
- Author(s)
  Ono K, Jung M, Zhang T, Tsutsuki H, Sezaki H, Ihara H, Wei FY, Tomizawa K, Akaike T, Sawa T.
- Journal Title
  
  Free Radic Biol Med
  
  Volume: 106 Pages: 69-79
- DOI
  10.1016/j.freeradbiomed.2017.02.023
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-16H04674, KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-15K08178, KAKENHI-PROJECT-16K13089, KAKENHI-PROJECT-16K15208
[Journal Article] Silver nanoparticles as potential antibiofilm agents against human pathogenic bacteria2017
- Author(s)
  Kyaw K, Harada A, Ichimaru H, Kawagoe T, Yahiro K, Morimura S, Ono K, Tsutsuki H, Sawa T, Niidome T.
- Journal Title
  
  Chem Lett
  
  Volume: 46 Issue: 4 Pages: 594-596
- DOI
  10.1246/cl.161198
- NAID
  130005549076
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-16K08770
[Journal Article] Protein polysulfidation-dependent persulfide dioxygenase activity of ethylmalonic encephalopathy protein 12016
- Author(s)
  Jung M, Kasamatsu S, Matsunaga T, Akashi S, Ono K, Nishimura A, Morita M, Abdul Hamid H, Fujii S, Kitamura H, Sawa T, Ida T, Motohashi H, Akaike T.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 480 Issue: 2 Pages: 180-186
- DOI
  10.1016/j.bbrc.2016.10.022
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H04692, KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-14J05470, KAKENHI-PROJECT-16K15228, KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-16K15208, KAKENHI-PROJECT-15K20855, KAKENHI-PROJECT-15K20857, KAKENHI-PROJECT-15K20876
[Journal Article] Persistent activation of cGMP-dependent protein kinase by a nitrated cyclic nucleotide via site specific protein S-guanylation2016
- Author(s)
  Akashi S, Ahmed KA, Sawa T, Ono K, Tsutsuki H, Burgoyne JR, Ida T, Horio E, Prysyazhna O, Oike Y, Rahaman MM, Eaton P, Fujii S, Akaike T.
- Journal Title
  
  Biochemistry
  
  Volume: 55 Issue: 5 Pages: 751-761
- DOI
  10.1021/acs.biochem.5b00774
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08456, KAKENHI-PROJECT-15K20876, KAKENHI-PUBLICLY-15H01520, KAKENHI-PUBLICLY-26116722, KAKENHI-PROJECT-25220103, KAKENHI-PROJECT-15H03115, KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-14J05470, KAKENHI-PROJECT-26670131, KAKENHI-PROJECT-26670207, KAKENHI-PROJECT-26293190, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25253020, KAKENHI-PROJECT-26670405
[Journal Article] The Chemical Biology of Hydropersulfides (RSSH): Chemical Stability, Reactivity and Redox Roles.2015
- Author(s)
  Saund, S. S., Sosa, V., Henriquez, S., Nguyen, Q. N. N., Soeda, S., Bianco, C. L., Millikin, R., White, C., Le, H., Ono, K., Tantillo, D. J., Kumagai, Y., Akaike, T., Lin, J., Fukuto, J. M.
- Journal Title
  
  Arch. Biochem. Biophys.
  
  Volume: 588 Pages: 15-24
- DOI
  10.1016/j.abb.2015.10.016
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06509, KAKENHI-PROJECT-26670207, KAKENHI-PLANNED-26111008, KAKENHI-PROJECT-25253020
[Presentation] Identification and quantification of β-lactam ring opened carbothioic S-acids mediated by cysteine hydropersulfide in bacteria2022
- Author(s)
  Katsuhiko Ono, Hiroyasu Tsutsuki, Tianli Zhang, Takaaki Akaike, Tomohiro Sawa
- Organizer
  The 12th International NO Conference & The 22nd NOSJ
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05443
[Presentation] N-Acetyl-L-cysteine polysulfides act as potent polysulfide donors and mitigate lethal endotoxin shock via their anti-inflammatory effects.2019
- Author(s)
  Zhang, T., Ono, K., Tsutsuki, H., Ihara, H., Islam, W., Akaike, T., Sawa, T.
- Organizer
  The 9th Biennial Meeting of Society for Free Radical Research-Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02098
[Presentation] N-Acetyl-L-cysteine polysulfides act as potent polysulfide donors and mitigate lethal endotoxin shock via their anti-inflammatory effects.2019
- Author(s)
  Zhang, T., Ono, K., Tsutsuki, H., Ihara, H., Islam, W., Akaike, T., Sawa, T.
- Organizer
  The 9th Biennial Meeting of Society for Free Radical Research-Asia
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22258
[Presentation] ．活性イオウによる自然免疫応答の制御機構2018
- Author(s)
  澤　智裕，張　田力，津々木博康，小野勝彦
- Organizer
  第45回日本毒性学会学術集会
- Data Source
  KAKENHI-PROJECT-18H02098
[Presentation] 活性イオウによる自然免疫応答の制御機構2018
- Author(s)
  澤　智裕，張　田力，津々木博康，小野勝彦
- Organizer
  第45回日本毒性学会学術集会
- Data Source
  KAKENHI-PROJECT-17K19205
[Presentation] チオール基とβラクタム系抗生物質の反応性に基づく新規βラクタム－タンパク質付加体形性の同定とその生物学的意義の解明2017
- Author(s)
  小野勝彦、津々木博康、張田力、瀬崎浩史、赤池孝章、澤智裕
- Organizer
  第９０回日本細菌学会総会
- Place of Presentation
  仙台
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-15H06509
[Presentation] チオール化合物とβラクタム系抗生物質との反応による付加体形成：抗菌作用への影響と標的タンパク質の同定2016
- Author(s)
  小野勝彦, 津々木博康, 赤池孝章, 澤　智裕
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15H06509
[Presentation] Rp-ニトロcGMPによるS-グアニル化を介したプロテインキナーゼG（PKG）の活性阻害2016
- Author(s)
  小野　勝彦、Ahtesham Ahmed Khandarker、津々木　博康、張　田力、井田　智章、宮田　敬士、尾池　雄一、赤池　孝章、澤　智裕
- Organizer
  第69回日本酸化ストレス学会学術集会
- Place of Presentation
  仙台
- Year and Date
  2016-08-30
- Data Source
  KAKENHI-PROJECT-15H06509
[Presentation] 腸管出血性大腸菌毒素 Subtilase cytotoxin によるインフラマソーム抑制機構の解析2016
- Author(s)
  津々木博康, Thianli Zhang, 小野勝彦, 八尋錦之助, 野田広俊, 澤　智裕
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15H06509
[Presentation] 細菌におけるシステインパースルフィド関連分子の生成動態2016
- Author(s)
  澤　智裕, 張　田力, 小野勝彦, 津々木博康, 赤池孝章
- Organizer
  第89回日本細菌学会総会
- Place of Presentation
  大阪国際交流センター（大阪市）
- Year and Date
  2016-03-23
- Data Source
  KAKENHI-PROJECT-15H06509
[Presentation] 大腸菌における蛋白質S-グアニル化の制御因子と標的タンパク質の同定2015
- Author(s)
  津々木博康、小野勝彦、井田智章、張　田力、居原　秀、赤池孝章、澤　智裕
- Organizer
  第68回日本細菌学会九州支部総会第52回日本ウイルス学会九州支部総会
- Place of Presentation
  別府コンベンションプラザ・ビーコンプラザ（大分県別府市）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-15H06509
[Presentation] 細菌におけるシステインパースルフィドおよび関連分子の生成動態2015
- Author(s)
  小野勝彦、津々木博康、張　田力、赤池孝章、澤　智裕
- Organizer
  第68回日本細菌学会九州支部総会第52回日本ウイルス学会九州支部総会
- Place of Presentation
  別府コンベンションプラザ・ビーコンプラザ（大分県別府市）
- Year and Date
  2015-09-04
- Data Source
  KAKENHI-PROJECT-15H06509

1. Sawa Tomohiro (30284756)

# of Collaborated Projects: 4 results

# of Collaborated Products: 9 results
2. Tsutsuki Hiroyasu (40586608)

# of Collaborated Projects: 4 results

# of Collaborated Products: 8 results
3. 荒木令江 (80253722)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 井田智章

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
5. 赤池孝章

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
6. 武田弘資

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 藤井重元

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ono katsuhiko 小野 勝彦

Ono Katsuhiko 小野 勝彦

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細菌における没食子酸誘導体の新規標的分子の探索Principal Investigator

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超硫黄分子がもたらす細菌の新規薬剤耐性機構の解明Principal Investigator

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Molecular mechanisms of inhibitory regulation of NLRP3 inflammasome by reactive sulfur species

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Mechanisms of intracellular bacterial killing induced by reactive sulfur species

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Molecular mechanisms of NLRP3 inflammasome activation via glutathione efflux

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Reactive sulfur metabolomics for the study of cellular sulfur dynamics

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Study of the reaction between beta-lactam antibiotids and thiol compoundsPrincipal Investigator

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[Journal Article] Styrene Maleic Acid Polymer-Encapsulated Chlorophyll as a Stable Micellar Nanoprobe for Advanced Anticancer Photodynamic Therapy2023

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[Journal Article] Alkyl gallates inhibit serine O-acetyltransferase in bacteria and enhance susceptibility of drug-resistant Gram-negative bacteria to antibiotics2023

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[Journal Article] Cystathionine γ-lyase self-inactivates by polysulfidation during cystine metabolism2023

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[Journal Article] Structural Determination of the Nanocomplex of Borate with Styrene-Maleic Acid Copolymer-Conjugated Glucosamine Used as a Multifunctional Anticancer Drug2022

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[Journal Article] Subtilase cytotoxin from Shiga-toxigenic Escherichia coli impairs the inflammasome and exacerbates enteropathogenic bacterial infection.2022

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[Journal Article] ATP exposure stimulates glutathione efflux as a necessary switch for NLRP3 inflammasome activation.2021

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[Journal Article] Cysteine hydropersulfide inactivates β-lactam antibiotics to form ring opened carbothioic S-acids in bacteria.2021

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ono katsuhiko 小野勝彦

Ono Katsuhiko 小野勝彦