Otsubo Yoko 大坪瑶子

Researcher Number	80580266
Other IDs
Affiliation (Current)	2025: 東京大学, 生命科学ネットワーク, 特任助教
Affiliation (based on the past Project Information) *help	2025: 東京大学, 生命科学ネットワーク, 特任助教 2019 – 2021: 核融合科学研究所, ヘリカル研究部, 特任助教 2017 – 2018: 基礎生物学研究所, 細胞応答研究室, 特任助教 2016: 基礎生物学研究所, 細胞応答研究室, 特別研究員
Review Section/Research Field	Principal Investigator Basic Section 14030:Applied plasma science-related / Basic Section 44010:Cell biology-related / Cell biology
Keywords	Principal Investigator 分裂酵母 / 有性生殖開始 / 細胞内シグナル伝達 / tRNA / 有性生殖 / TORキナーゼ / 栄養応答 / プラズマバイオロジー / ストレス応答 / シグナル伝達

常温大気圧プラズマに対する細胞の応答機構の解明と細胞進化への応用Principal Investigator
- Principal Investigator
  
  大坪瑶子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 14030:Applied plasma science-related
- Research Institution
  The University of Tokyo
Molecular mechanisms underlying cellular responses to nutrient starvation in fission yeastPrincipal Investigator
- Principal Investigator
  
  Otsubo Yoko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  National Institute for Fusion Science
Analysis of novel nutrient response mutants in fission yeastPrincipal Investigator
- Principal Investigator
  
  Otsubo Yoko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cell biology
- Research Institution
  National Institute for Basic Biology

All 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Cdc13 (cyclin B) is degraded by autophagy under sulfur depletion in fission yeast2022
- Author(s)
  Ohtsuka Hokuto、Hatta Yoshiko、Hayashi Kana、Shimasaki Takafumi、Otsubo Yoko、Ito Yurika、Tsutsui Yu、Hattori Nobutake、Yamashita Akira、Murakami Hiroshi、Aiba Hirofumi
- Journal Title
  
  Autophagy Reports
  
  Volume: 1 Issue: 1 Pages: 51-64
- DOI
  10.1080/27694127.2022.2047442
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06649, KAKENHI-PROJECT-19K15730, KAKENHI-PROJECT-20K06500, KAKENHI-PROJECT-21K05363, KAKENHI-PROJECT-20H02898
[Journal Article] Magnesium depletion extends fission yeast lifespan via general amino acid control activation2021
- Author(s)
  Ohtsuka Hokuto、Kobayashi Mikuto、Shimasaki Takafumi、Sato Teppei、Akanuma Genki、Kitaura Yasuyuki、Otsubo Yoko、Yamashita Akira、Aiba Hirofumi
- Journal Title
  
  MicrobiologyOpen
  
  Volume: 10 Issue: 2 Pages: 1176-1176
- DOI
  10.1002/mbo3.1176
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06649, KAKENHI-PROJECT-20K05790, KAKENHI-PROJECT-19K15730, KAKENHI-PROJECT-20H02898, KAKENHI-PROJECT-20K06500
[Journal Article] Insights into normothermic treatment with direct irradiation of atmospheric pressure plasma for biological applications2020
- Author(s)
  Yoshimura Shinji、Otsubo Yoko、Yamashita Akira、Ishikawa Kenji
- Journal Title
  
  Japanese Journal of Applied Physics
  
  Volume: 60 Issue: 1 Pages: 010502-010502
- DOI
  10.35848/1347-4065/abcbd2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06649, KAKENHI-PROJECT-20K06500, KAKENHI-PROJECT-19H05462
[Journal Article] Meiotic gene silencing complex MTREC/NURS recruits the nuclear exosome to YTH-RNA-binding protein Mmi12020
- Author(s)
  Shichino Yuichi、Otsubo Yoko、Yamamoto Masayuki、Yamashita Akira
- Journal Title
  
  PLOS Genetics
  
  Volume: 16 Issue: 2 Pages: e1008598-e1008598
- DOI
  10.1371/journal.pgen.1008598
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06649, KAKENHI-PROJECT-19J00920
[Journal Article] Novel Links between TORC1 and Traditional Non-Coding RNA, tRNA2020
- Author(s)
  Otsubo Yoko、Kamada Yoshiaki、Yamashita Akira
- Journal Title
  
  Genes
  
  Volume: 11 Issue: 9 Pages: 956-956
- DOI
  10.3390/genes11090956
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06649, KAKENHI-PROJECT-19K06668, KAKENHI-PROJECT-20K06500
[Journal Article] YTH-RNA-binding protein prevents deleterious expression of meiotic proteins by tethering their mRNAs to nuclear foci2018
- Author(s)
  Shichino Yuichi、Otsubo Yoko、Kimori Yoshitaka、Yamamoto Masayuki、Yamashita Akira
- Journal Title
  
  eLife
  
  Volume: 7
- DOI
  10.7554/elife.32155
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K00261, KAKENHI-PROJECT-16K18542, KAKENHI-PROJECT-15H04333, KAKENHI-PROJECT-15J40037
[Journal Article] tRNA production links nutrient conditions to the onset of sexual differentiation through the TORC1 pathway2018
- Author(s)
  Otsubo Yoko、Matsuo Tomohiko、Nishimura Akiko、Yamamoto Masayuki、Yamashita Akira
- Journal Title
  
  EMBO Reports
  
  Volume: 19 Issue: 3
- DOI
  10.15252/embr.201744867
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07445, KAKENHI-PROJECT-16K18542, KAKENHI-PROJECT-15H04333, KAKENHI-PROJECT-15J40037
[Journal Article] TORC1-Dependent Phosphorylation Targets in Fission Yeast2017
- Author(s)
  Otsubo Yoko、Nakashima Akio、Yamamoto Masayuki、Yamashita Akira
- Journal Title
  
  Biomolecules
  
  Volume: 7 Issue: 3 Pages: 50-50
- DOI
  10.3390/biom7030050
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18542, KAKENHI-PROJECT-15H04333, KAKENHI-PROJECT-15J40037, KAKENHI-PROJECT-26440053
[Presentation] 酵母を用いた常温大気圧プラズマに対する細胞応答機構の解明2022
- Author(s)
  大坪瑶子、定塚勝樹、吉村信次、山下朗
- Organizer
  日本物理学会第77回年次大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K06649
[Presentation] 分裂酵母のTORC1 biosensorの開発2021
- Author(s)
  山下朗、後藤祐平、酒井啓一郎、大坪瑶子、青木一洋
- Organizer
  第11回TOR研究会
- Data Source
  KAKENHI-PROJECT-19K06649
[Presentation] Development of single-cell measurement system by using FRET biosensors of the TORC1 activity in living yeast cells2020
- Author(s)
  後藤祐平、大坪瑶子、鎌田芳彰、山下朗、青木一洋
- Organizer
  第3回ExCELLSシンポジウム
- Data Source
  KAKENHI-PROJECT-19K06649
[Presentation] 分裂酵母の Red1 による減数分裂転写産物の選択的分解機構2019
- Author(s)
  七野悠一、大坪瑶子、山本正幸、山下朗
- Organizer
  第52回酵母遺伝学フォーラム研究報告会
- Data Source
  KAKENHI-PROJECT-19K06649
[Presentation] 分裂酵母のRed1による減数分裂転写産物の選択的分解機構2019
- Author(s)
  七野悠一、大坪瑶子、山本正幸、山下朗
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-19K06649
[Presentation] 酵母一細胞レベルでのTORC1活性測定法の開発2019
- Author(s)
  後藤祐平、大坪瑶子、鎌田芳彰、山下朗、青木一洋
- Organizer
  第二回ExCELLSシンポジウム
- Data Source
  KAKENHI-PROJECT-19K06649
[Presentation] 分裂酵母TORC1経路の細胞生物学的解析2019
- Author(s)
  山下朗、大坪瑶子、後藤祐平、青木一洋
- Organizer
  第9回TOR研究会
- Data Source
  KAKENHI-PROJECT-19K06649
[Presentation] tRNA前駆体によるTORキナーゼ活性調節機構2018
- Author(s)
  大坪瑶子、山本正幸、山下朗
- Organizer
  第20回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-16K18542
[Presentation] Novel regulatory factors in the TORC1-mediated nutrient sensing pathway in fission yeast2018
- Author(s)
  Otsubo Yoko, Yamamoto Masayuki, Yamashita Akira
- Organizer
  第41回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18542
[Presentation] 分裂酵母S. pombeのtRNA前駆体によるTORC1制御2018
- Author(s)
  大坪瑶子、山本正幸、山下朗
- Organizer
  酵母遺伝学フォーラム第51回研究報告会
- Data Source
  KAKENHI-PROJECT-16K18542
[Presentation] 分裂酵母のtRNA前駆体によるTORC1制御2017
- Author(s)
  大坪瑶子、山本正幸、山下朗
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K18542
[Presentation] 分裂酵母におけるtRNA前駆体によるTORC1制御の可能性2017
- Author(s)
  大坪瑶子、山本正幸、山下朗
- Organizer
  第6回TOR研究会
- Data Source
  KAKENHI-PROJECT-16K18542
[Presentation] 減数分裂における分裂酵母TORC1の制御2017
- Author(s)
  中嶋昭雄、山下朗、大坪瑶子、松田真弥、鎌田真司、瓜谷眞裕、山本正幸、吉川潮
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16K18542
[Presentation] 分裂酵母におけるtRNA前駆体によるTORC1制御2017
- Author(s)
  大坪瑶子、山本正幸、山下朗
- Organizer
  日本遺伝学会第89回大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18542
[Presentation] 分裂酵母におけるtRNA前駆体によるTORC1制御の可能性2016
- Author(s)
  大坪瑶子、山本正幸、山下朗
- Organizer
  第6回TOR研究会
- Place of Presentation
  東京大学　分子細胞生物学研究所　(東京都　文京区)
- Year and Date
  2016-09-30
- Data Source
  KAKENHI-PROJECT-16K18542

1. 吉村信次 (50311204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 木森義隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 松尾朋彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Otsubo Yoko 大坪 瑶子

Research Projects

Research Products

Co-Researchers

常温大気圧プラズマに対する細胞の応答機構の解明と細胞進化への応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular mechanisms underlying cellular responses to nutrient starvation in fission yeastPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of novel nutrient response mutants in fission yeastPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cdc13 (cyclin B) is degraded by autophagy under sulfur depletion in fission yeast2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Magnesium depletion extends fission yeast lifespan via general amino acid control activation2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Insights into normothermic treatment with direct irradiation of atmospheric pressure plasma for biological applications2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Meiotic gene silencing complex MTREC/NURS recruits the nuclear exosome to YTH-RNA-binding protein Mmi12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel Links between TORC1 and Traditional Non-Coding RNA, tRNA2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] YTH-RNA-binding protein prevents deleterious expression of meiotic proteins by tethering their mRNAs to nuclear foci2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] tRNA production links nutrient conditions to the onset of sexual differentiation through the TORC1 pathway2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TORC1-Dependent Phosphorylation Targets in Fission Yeast2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] 酵母を用いた常温大気圧プラズマに対する細胞応答機構の解明2022

Author(s)

Organizer

Data Source

[Presentation] 分裂酵母のTORC1 biosensorの開発2021

Author(s)

Organizer

Data Source

[Presentation] Development of single-cell measurement system by using FRET biosensors of the TORC1 activity in living yeast cells2020

Author(s)

Organizer

Data Source

[Presentation] 分裂酵母の Red1 による減数分裂転写産物の選択的分解機構2019

Author(s)

Organizer

Data Source

[Presentation] 分裂酵母のRed1による減数分裂転写産物の選択的分解機構2019

Author(s)

Otsubo Yoko 大坪瑶子