HAYASHI Yoshinori 林良憲

Researcher Number	80582717
Other IDs
Affiliation (Current)	2025: 日本大学, 歯学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 日本大学, 歯学部, 准教授 2019: 日本大学, 歯学部, 助教 2016 – 2018: 九州大学, 歯学研究院, 講師 2012 – 2014: 九州大学, 歯学研究科(研究院), 助教 2012 – 2014: 九州大学, 歯学研究院, 助教
Review Section/Research Field	Principal Investigator Functional basic dentistry / Basic Section 57060:Surgical dentistry-related / Basic Section 57010:Oral biological science-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Basic Section 57010:Oral biological science-related / Functional basic dentistry
Keywords	Principal Investigator 神経障害性疼痛 / IL-33 / 三叉神経節ニューロン / 機械アロディニア / Caイメージング / 三叉神経節 / インターロイキン / アロディニア / Fyn kinase / GluN2B … More / インターロイキン33 / インターロイキン-33 / 三叉神経脊髄路核尾側亜核 / Fynキナーゼ / パッチクランプ / NR2B / オリゴデンドロサイト / 神経障害生疼痛 / 脊髄後根神経節 / 歯髄幹細胞 / ヒト乳歯歯髄幹細胞 / 機械的アロディニア / 慢性疼痛 / 一次求心性神経 / 好中球 / カテプシンE / 国際情報交換 / 疼痛過敏 / 痛覚過敏 / モルヒネ / BKチャネル / ミクログリア … More Except Principal Investigator 三叉神経節 / 神経障害性疼痛 / ミクログリア / マクロファージ / Legumain / オプトジェネティクス / in vivo カルシウムイメージング / 口腔癌性疼痛 / サテライト細胞 / 口腔顔面痛 / 心理社会的ストレス / 疼痛 / グリア細胞 / シスプラチン / 衛星細胞 / 頭頸部疼痛 / 母子分離ストレス / 一次侵害受容ニューロン / 幼少期ストレス / 三叉神経障害性疼痛 / 三叉神経脊髄路核尾側亜核 / IFN-gamma / 一酸化窒素 / 下歯槽神経損傷 / 異所性疼痛 / IFN- γ / Unc93b / TOLL様受容体と慢性疼痛 / Toll様受容体 / 歯科薬理学 / IL-18 / NF-κB / カスパーゼ-1 / IL-1β / IFN-γ / T細胞 / オートファジー / モルヒネ / 慢性疼痛 / 炎症性疼痛 / クロモグラニンA / カテプシンS / カテプシンB Less

Role of satellite cells in trigeminal ganglion in psychosocial stress-induced orofacial pain
- Principal Investigator
  
  澁田郁子 (鈴木郁子)
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
三叉神経節ニューロンの新たな可塑性の獲得様式の同定による神経障害性疼痛の解明Principal Investigator
- Principal Investigator
  
  林良憲
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Elucidation of a new molecular mechanism of oral cancer pain based on plastic changes in the intercellular network in the trigeminal ganglion
- Principal Investigator
  
  篠田雅路
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Fundamental study of the development of new therapy for the treatment of anticancer drug-induced persistent pain targeting glial cell activation
- Principal Investigator
  
  岩田幸一
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nihon University
Orofacial pain mechanism due to infant stress
- Principal Investigator
  
  SHIBUTA Ikuko
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Nihon University
Discovery of novel pain markers in projection neuronsPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshinori
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nihon University
Macrophages in trigeminal ganglion contributes to the ectopic orofacial pain following inferior alveolar nerve injury
- Principal Investigator
  
  SHINODA Masamichi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57010:Oral biological science-related
- Research Institution
  Nihon University
Therapeutic mechanisms of chronic pain by dental pulp stem cellsPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshinori
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Nihon University
  Kyushu University
Critical roles of the chromogranin A-cathepsin B system in a transition of acute pain to a chronic pain state
- Principal Investigator
  
  HIROSHI Nakanishi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Involvement of endosomal Toll-like receptors in the development of neuropathic pain
- Principal Investigator
  
  HIROSHI Nakanishi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University
Novel role of microglial BK channels on chronic painPrincipal Investigator
- Principal Investigator
  
  HAYASHI Yoshinori
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Functional basic dentistry
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] NMDAレセプターとミクログリア：ミクログリアのシナプス可塑性ならびにシナプス再編への関与2013
- Author(s)
  林　良憲、中西　博
- Total Pages
  26
- Publisher
  日本神経精神薬理学雑誌
- Data Source
  KAKENHI-PROJECT-24659827
[Book] BK+ Channels Contributes to the Cellular Activation of Microglia: A big Channel in Small Glia2013
- Author(s)
  Hayashi Y, Nakanishi H
- Total Pages
  9
- Publisher
  NOVA Publishers
- Data Source
  KAKENHI-PROJECT-24791979
[Book] BK+ channels contribute to the cellular activation of microglia : a big channel in small glia, In: Glial Cells: Embryonic Development, Types/Functions and Role in Disease2013
- Author(s)
  Yoshinori Hayashi, Hiroshi Nakanishi
- Total Pages
  18
- Publisher
  Nova Science Publishers, Inc.
- Data Source
  KAKENHI-PROJECT-24659827
[Journal Article] Analgesic effect of linalool odor on oral ulcerative mucositis-induced pain in rats2024
- Author(s)
  Iida Masato、Hitomi Suzuro、Hayashi Yoshinori、Shibuta Ikuko、Tsuboi Yoshiyuki、Ueda Koichiro、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  Brain Research Bulletin
  
  Volume: 206 Pages: 110844-110844
- DOI
  10.1016/j.brainresbull.2023.110844
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09907, KAKENHI-PROJECT-23K09130
[Journal Article] Astrocytic and microglial interleukin-1β mediates complement C1q-triggered orofacial mechanical allodynia2023
- Author(s)
  Hong Chaoli、Hayashi Yoshinori、Hitomi Suzuro、Kurisu Ryoko、Urata Kentaro、Shibuta Ikuko、Toyofuku Akira、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  Neuroscience Research
  
  Volume: 188 Pages: 68-74
- DOI
  10.1016/j.neures.2022.10.009
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10141, KAKENHI-PROJECT-20K09896
[Journal Article] Neonatal Injury Modulates Incisional Pain Sensitivity in Adulthood: An Animal Study2023
- Author(s)
  Soma Kumi、Hitomi Suzuro、Hayashi Yoshinori、Soma Chihiro、Otsuji Jo、Shibuta Ikuko、Furukawa Akihiko、Urata Kentaro、Kurisu Ryoko、Yonemoto Mamiko、Hojo Yasushi、Shirakawa Tetsuo、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  Neuroscience
  
  Volume: 519 Pages: 60-72
- DOI
  10.1016/j.neuroscience.2023.03.018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K10064, KAKENHI-PROJECT-20K09894, KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-21K10123, KAKENHI-PROJECT-21K10172
[Journal Article] Age-related Changes in Trigeminal Ganglion Macrophages Enhance Orofacial Ectopic Pain After Inferior Alveolar Nerve Injury2023
- Author(s)
  FUJIWARA SHINTARO、URATA KENTARO、OTO TATSUKI、HAYASHI YOSHINORI、HITOMI SUZURO、IWATA KOICHI、IINUMA TOSHIMITSU、SHINODA MASAMICHI
- Journal Title
  
  In Vivo
  
  Volume: 37 Issue: 1 Pages: 132-142
- DOI
  10.21873/invivo.13062
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K10064, KAKENHI-PROJECT-20K09896
[Journal Article] Involvement of oxidative stress in orofacial mechanical pain hypersensitivity following neonatal maternal separation in rats2023
- Author(s)
  Soma Chihiro、Hitomi Suzuro、Oshima Eri、Hayashi Yoshinori、Soma Kumi、Shibuta Ikuko、Tsuboi Yoshiyuki、Shirakawa Tetsuo、Kikuiri Takashi、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 22760-22760
- DOI
  10.1038/s41598-023-50116-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K09130, KAKENHI-PROJECT-21K10123, KAKENHI-PROJECT-21K10172
[Journal Article] Decreased PPARgamma in the trigeminal spinal subnucleus caudalis due to neonatal injury contributes to incision-induced mechanical allodynia in female rats2022
- Author(s)
  Otsuji Jo、Hayashi Yoshinori、Hitomi Suzuro、Soma Chihiro、Soma Kumi、Shibuta Ikuko、Iwata Koichi、Shirakawa Tetsuo、Shinoda Masamichi
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 19314-19314
- DOI
  10.1038/s41598-022-23832-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10123, KAKENHI-PROJECT-20K09896
[Journal Article] Age-Related Differences in Transient Receptor Potential Vanilloid 1 and 2 Expression Patterns in the Trigeminal Ganglion Neurons Contribute to Changes in the Palatal Mucosal Heat Pain Sensitivity2022
- Author(s)
  Oto Tatsuki、Urata Kentaro、Hayashi Yoshinori、Hitomi Suzuro、Shibuta Ikuko、Iwata Koichi、Iinuma Toshimitsu、Shinoda Masamichi
- Journal Title
  
  Tohoku J. Exp. Med.
  
  Volume: 256 Issue: 4 Pages: 283-290
- DOI
  10.1620/tjem.2022.J004
- ISSN
  0040-8727, 1349-3329
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K18619, KAKENHI-PROJECT-20K09896
[Journal Article] Plastic changes in nociceptive pathways contributing to persistent orofacial pain2022
- Author(s)
  Shinoda Masamichi、Hitomi Suzuro、Iwata Koichi、Hayashi Yoshinori
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: 64 Issue: 3 Pages: 263-270
- DOI
  10.1016/j.job.2022.07.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09896
[Journal Article] Butyric acid modulates periodontal nociception in <i>Porphyromonas gingivalis</i>-induced periodontitis2022
- Author(s)
  Murakami Naoki、Yoshikawa Kenji、Tsukada Kohei、Kamio Noriaki、Hayashi Yoshinori、Hitomi Suzuro、Kimura Yuki、Shibuta Ikuko、Osada Ayaka、Sato Shuichi、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  Journal of Oral Science
  
  Volume: 64 Issue: 1 Pages: 91-94
- DOI
  10.2334/josnusd.21-0483
- NAID
  130008142667
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K10265, KAKENHI-PROJECT-20K09896
[Journal Article] IL-33 induces orofacial neuropathic pain through Fyn-dependent phosphorylation of GluN2B in the trigeminal spinal subnucleus caudalis2022
- Author(s)
  Kimura Yuki、Hayashi Yoshinori、Hitomi Suzuro、Ikutame Daisuke、Urata Kentaro、Shibuta Ikuko、Sakai Atsushi、Ni Junjun、Iwata Koichi、Tonogi Morio、Shinoda Masamichi
- Journal Title
  
  Brain, Behavior, and Immunity
  
  Volume: 99 Pages: 266-280
- DOI
  10.1016/j.bbi.2021.10.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09896
[Journal Article] Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia2022
- Author(s)
  Sugisawa Erika、Kondo Takeshi、Kumagai Yutaro、Kato Hiroki、Takayama Yasunori、Isohashi Kayako、Shimosegawa Eku、Takemura Naoki、Hayashi Yoshinori、Sasaki Takuya、Martino Mika?l M.、Tominaga Makoto、Maruyama Kenta
- Journal Title
  
  Cell Reports
  
  Volume: 38 Issue: 10 Pages: 110462-110462
- DOI
  10.1016/j.celrep.2022.110462
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03114, KAKENHI-PROJECT-21K19083, KAKENHI-PROJECT-18K07296, KAKENHI-PROJECT-20K09896, KAKENHI-ORGANIZER-21H05238
[Journal Article] Microglial cathepsin E plays a role in neuroinflammation and amyloid β production in Alzheimer’s disease2022
- Author(s)
  Xie Zhen、Meng Jie、Kong Wei、Wu Zhou、Lan Fei、Narengaowa、Hayashi Yoshinori、Yang Qinghu、Bai Zhantao、Nakanishi Hiroshi、Qing Hong、Ni Junjun
- Journal Title
  
  Aging Cell
  
  Volume: 21 Issue: 3
- DOI
  10.1111/acel.13565
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06383, KAKENHI-PROJECT-20K09896
[Journal Article] Pannexin 1 role in the trigeminal ganglion in infraorbital nerve injury‐induced mechanical allodynia2022
- Author(s)
  Kurisu Ryoko、Saigusa Tadashi、Aono Yuri、Hayashi Yoshinori、Hitomi Suzuro、Shimada Masahiko、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  Oral Diseases
  
  Volume: - Issue: 4 Pages: 14129-14129
- DOI
  10.1111/odi.14129
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09896
[Journal Article] Effect of low‐intensity pulsed ultrasound on orofacial sensory disturbance following inferior alveolar nerve injury: Role of neurotrophin‐3 signaling2021
- Author(s)
  Tsuchimochi Akane、Endo Chitose、Motoyoshi Mitsuru、Tamura Miki、Hitomi Suzuro、Hayashi Yoshinori、Shinoda Masamichi
- Journal Title
  
  European Journal of Oral Sciences
  
  Volume: 129 Issue: 5
- DOI
  10.1111/eos.12810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09896
[Journal Article] Orofacial Neuropathic Pain-Basic Research and Their Clinical Relevancies2021
- Author(s)
  Shinoda Masamichi、Imamura Yoshiki、Hayashi Yoshinori、Noma Noboru、Okada-Ogawa Akiko、Hitomi Suzuro、Iwata Koichi
- Journal Title
  
  Frontiers in Molecular Neuroscience
  
  Volume: 14 Pages: 691396-691396
- DOI
  10.3389/fnmol.2021.691396
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10049, KAKENHI-PROJECT-18K09801, KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-20K10192
[Journal Article] Microglial circadian clock regulation of microglial structural complexity, dendritic spine density and inflammatory response2021
- Author(s)
  Nakanishi Hiroshi、Ni Junjun、Nonaka Saori、Hayashi Yoshinori
- Journal Title
  
  Neurochemistry International
  
  Volume: 142 Pages: 104905-104905
- DOI
  10.1016/j.neuint.2020.104905
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K19650
[Journal Article] Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury2021
- Author(s)
  Liu Yicong、Li Hui、Hu Jiangqi、Wu Zhou、Meng Jie、Hayashi Yoshinori、Nakanishi Hiroshi、Qing Hong、Ni Junjun
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 59 Issue: 1 Pages: 717-730
- DOI
  10.1007/s12035-021-02594-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-21K06383
[Journal Article] Stem cells from human exfoliated deciduous teeth attenuate mechanical allodynia in mice through distinct from the siglec-9/MCP-1-mediated tissue-repairing mechanism2021
- Author(s)
  Hayashi Yoshinori、Kato Hiroki、Nonaka Kazuaki、Nakanishi Hiroshi
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 20053-20053
- DOI
  10.1038/s41598-021-99585-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-21K06383
[Journal Article] Pannexin 1-Mediated ATP Signaling in the Trigeminal Spinal Subnucleus Caudalis Is Involved in Tongue Cancer Pain2021
- Author(s)
  Ryo Koyama, Koichi Iwata, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Akihiko Furukawa, Sayaka Asano, Tadayoshi Kaneko, Yoshiyuki Yonehara, Masamichi Shinoda
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 22 Issue: 21 Pages: 11404-11404
- DOI
  10.3390/ijms222111404
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K16342, KAKENHI-PROJECT-20K09896
[Journal Article] Periodontal acidification contributes to tooth pain hypersensitivity during orthodontic tooth movement2021
- Author(s)
  Osada Ayaka、Hitomi Suzuro、Nakajima Akira、Hayashi Yoshinori、Shibuta Ikuko、Tsuboi Yoshiyuki、Motoyoshi Mitsuru、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  Neuroscience Research
  
  Volume: 177 Pages: 103-110
- DOI
  10.1016/j.neures.2021.11.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07746, KAKENHI-PROJECT-20K09894, KAKENHI-PROJECT-20K09896
[Journal Article] Pathophysiological mechanisms of persistent orofacial pain2020
- Author(s)
  Shinoda Masamichi、Hayashi Yoshinori、Kubo Asako、Iwata Koichi
- Journal Title
  
  Journal of Oral Science
  
  Volume: 62 Issue: 2 Pages: 131-135
- DOI
  10.2334/josnusd.19-0373
- NAID
  130007821522
- ISSN
  1343-4934, 1880-4926
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09541, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-17K11654, KAKENHI-PROJECT-20K09896
[Journal Article] Suppression of superficial microglial activation by spinal cord stimulation attenuates neuropathic pain following sciatic nerve injury in rats.2020
- Author(s)
  Shinoda M, Fujita S, Sugawara S, Asano S, Koyama R, Fujiwara S, Soma K, Tamagawa T, Matsui T, Ikutame D, Ando M, Osada A, Kimura Y, Kobayashi K, Yamamoto T, Kusama-Eguchi K, Kobayashi M, Hayashi Y, Iwata K.
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11477
[Journal Article] Suppression of superficial microglial activation by spinal cord stimulation attenuates neuropathic pain following sciatic nerve injury in rats.2020
- Author(s)
  Shinoda M, Fujita S, Sugawara S, Asano S, Koyama R, Fujiwara S, Soma K, Tamagawa T, Matsui T, Ikutame D, Ando M, Osada A, Kimura Y, Kobayashi K, Yamamoto T, Kusama-Eguchi K, Kobayashi M, Hayashi Y, Iwata K
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Issue: 7 Pages: 2390-2390
- DOI
  10.3390/ijms21072390
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K10064, KAKENHI-PROJECT-19H03821, KAKENHI-PROJECT-20K09896
[Journal Article] Neural stem cell?specific ITPA deficiency causes neural depolarization and epilepsy2020
- Author(s)
  Koga Yuichiro、Tsuchimoto Daisuke、Hayashi Yoshinori、Abolhassani Nona、Yoneshima Yasuto、Sakumi Kunihiko、Nakanishi Hiroshi、Toyokuni Shinya、Nakabeppu Yusaku
- Journal Title
  
  JCI Insight
  
  Volume: 5 Issue: 22
- DOI
  10.1172/jci.insight.140229
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K06960, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16H06276
[Journal Article] Involvement of Satellite Cell Activation via Nitric Oxide Signaling in Ectopic Orofacial Hypersensitivity2020
- Author(s)
  Lee Jun、Ohara Kinuyo、Shinoda Masamichi、Hayashi Yoshinori、Kubo Asako、Sugawara Shiori、Asano Sayaka、Soma Kumi、Kanno Kohei、Ando Masatoshi、Koyama Ryo、Kimura Yuki、Sakanashi Kousuke、Iinuma Toshimitsu、Iwata Koichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 4 Pages: 1252-1252
- DOI
  10.3390/ijms21041252
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09732, KAKENHI-PROJECT-19K10049, KAKENHI-PROJECT-18K17077, KAKENHI-PROJECT-16K11477
[Journal Article] Aging-Related Phenotypic Conversion of Medullary Microglia Enhances Intraoral Incisional Pain Sensitivity2020
- Author(s)
  Ikutame Daisuke、Urata Kentaro、Oto Tatsuki、Fujiwara Shintaro、Iinuma Toshimitsu、Shibuta Ikuko、Hayashi Yoshinori、Hitomi Suzuro、Iwata Koichi、Shinoda Masamichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 21 Pages: 7871-7871
- DOI
  10.3390/ijms21217871
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K09732
[Journal Article] Involvement of TNFα in the enhancement of hypersensitivity in the adulthood-injured face associated with facial injury in infancy2020
- Author(s)
  Soma Kumi、Shinoda Masamichi、Hayashi Yoshinori、Kanno Kohei、Shirakwa Tetsuo、Iwata Koichi
- Journal Title
  
  Neuroscience Research
  
  Volume: - Pages: 30657-1
- DOI
  10.1016/j.neures.2019.12.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-20K09896
[Journal Article] Oxytocin-dependent regulation of TRPs expression in trigeminal ganglion neurons attenuates orofacial neuropathic pain following intraorbital nerve injury in rats2020
- Author(s)
  Ando M, Hayashi Y, Hitomi S, Shibuta I, Furukawa A, Oto T, Inada T, Matsui T, Fukaya C, Noma N, Okubo M, Yonehara Y, Kaneko T, Iwata K, Shinoda M
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 21 Issue: 23 Pages: 9173-9190
- DOI
  10.3390/ijms21239173
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09466, KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-18K09732
[Journal Article] Microglia-Astrocyte Communication via C1q Contributes to Orofacial Neuropathic Pain Associated with Infraorbital Nerve Injury2020
- Author(s)
  Asano Sayaka、Hayashi Yoshinori、Iwata Koichi、Okada-Ogawa Akiko、Hitomi Suzuro、Shibuta Ikuko、Imamura Yoshiki、Shinoda Masamichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 18 Pages: 6834-6834
- DOI
  10.3390/ijms21186834
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09801, KAKENHI-PROJECT-20K09896, KAKENHI-PROJECT-20K10192, KAKENHI-PROJECT-18K09732
[Journal Article] KCNMB3 in spinal microglia contributes to the generation and maintenance of neuropathic pain in mice2019
- Author(s)
  Imari Kazuhisa、Harada Yuka、Zhang Jing、Mori Yoshihide、Hayashi Yoshinori
- Journal Title
  
  International Journal of Molecular Medicine
  
  Volume: - Pages: 1585-1593
- DOI
  10.3892/ijmm.2019.4279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11477
[Journal Article] Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion.2019
- Author(s)
  Matsuda T, Irie T, Katsurabayashi S, Hayashi Y, Nagai T, Hamazaki N, Adefuin AMD, Miura F, Ito T, Kimura H, Shirahige K, Takeda T, Iwasaki K, Imamura T, Nakashima K.
- Journal Title
  
  Neuron
  
  Volume: 101 (3) Issue: 3 Pages: 472-485
- DOI
  10.1016/j.neuron.2018.12.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08328, KAKENHI-PROJECT-18K14820, KAKENHI-PLANNED-16H06527, KAKENHI-PROJECT-16K11477
[Journal Article] A TLR-CXCL1 pathway in DRG neurons induces neutrophil accumulation in the DRG and mechanical allodynia in EAE mice2019
- Author(s)
  Zhang Jing、Harada Yuka、Hayashi Yoshinori
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 12003-12003
- DOI
  10.1038/s41598-019-48558-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11477
[Journal Article] Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis.2019
- Author(s)
  Harada Y, Zhang J, Imari K, Yamasaki R, Ni J, Wu Z, Yamamoto K, Kira JI, Nakanishi H, Hayashi Y.
- Journal Title
  
  Pain
  
  Volume: 160 Issue: 9 Pages: 2050-2062
- DOI
  10.1097/j.pain.0000000000001596
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-16K11477
[Journal Article] Increase in IGF-1 Expression in the Injured Infraorbital Nerve and Possible Implications for Orofacial Neuropathic Pain2019
- Author(s)
  Sugawara Shiori、Shinoda Masamichi、Hayashi Yoshinori、Saito Hiroto、Asano Sayaka、Kubo Asako、Shibuta Ikuko、Furukawa Akihiko、Toyofuku Akira、Iwata Koichi
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 20 Issue: 24 Pages: 6360-6360
- DOI
  10.3390/ijms20246360
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09732, KAKENHI-PROJECT-19K10328, KAKENHI-PROJECT-16K11477
[Journal Article] Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis.2019
- Author(s)
  Harada Y, Zhang J, Imari K, Yamasaki R, Ni J, Wu Z, Yamamoto K, Kira JI, Nakanishi H, Hayashi Y
- Journal Title
  
  Pain
  
  Volume: .
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11477
[Journal Article] Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion.2019
- Author(s)
  Matsuda T, Irie T, Katsurabayashi S*, Hayashi Y*, Nagai T, Hamazaki N, Adefuin AMD, Miura F, Ito T, Kimura H, Shirahige K, Takeda T, Iwasaki K, Imamura T, Nakashima K
- Journal Title
  
  Neuron
  
  Volume: 101 Pages: 472-485
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11477
[Journal Article] Peripheral and Central Mechanisms of Persistent Orofacial Pain2019
- Author(s)
  Shinoda Masamichi、Kubo Asako、Hayashi Yoshinori、Iwata Koichi
- Journal Title
  
  Frontiers in Neuroscience
  
  Volume: 13 Pages: 1-10
- DOI
  10.3389/fnins.2019.01227
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09541, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-17K11654
[Journal Article] Enantioselective Monoclonal Antibodies for Detecting Ketamine to Crack Down on Illicit Use2018
- Author(s)
  Morita, I. Oyama, H. Kanda, Y. Yasuo, M. Ito, A. Toyota, M. Hayashi, Y. Yokoyama, T. Kobayashi, N.
- Journal Title
  
  Biological and Pharmaceutical Bulletin
  
  Volume: 41 Issue: 1 Pages: 123-131
- DOI
  10.1248/bpb.b17-00762
- NAID
  130006301299
- ISSN
  0918-6158, 1347-5215
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K08953, KAKENHI-PROJECT-16K08954
[Journal Article] Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice.2018
- Author(s)
  Ni J, Wu Z, Stoka V, Meng J, Hayashi Y, Peters C, Qing H, Turk V, Nakanishi H. Increased expression and altered subcellular distribution of cathepsin B in microglia induce cognitive impairment through oxidative stress and inflammatory response in mice
- Journal Title
  
  Aging Cell
  
  Volume: . Issue: 1
- DOI
  10.1111/acel.12856
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-17K17093
[Journal Article] A Novel Autoantibody against Plexin D1 in Patients with Neuropathic Pain.2018
- Author(s)
  Fujii T, Yamasaki R, Iinuma K, Tsuchimoto D, Hayashi Y, Saitoh BY, Matsushita T, Kido MA, Aishima S, Nakanishi H, Nakabeppu Y, Kira JI.
- Journal Title
  
  Annals of Neurology
  
  Volume: 84 Issue: 2 Pages: 208-224
- DOI
  10.1002/ana.25279
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-18K19650, KAKENHI-PROJECT-17K19663, KAKENHI-PROJECT-17H01391
[Journal Article] Overexpression of cathepsin E interferes with neuronal differentiation of P19 embryonal teratocarcinoma cells by degradation of N-cadherin.2017
- Author(s)
  Harada Y, Takayama F, Tanabe K, Ni J, Hayashu Y, Yamamoto K, Wu Z, Nakanishi H
- Journal Title
  
  10.1007/s10571-016-0376-x.
  
  Volume: 37 Issue: 3 Pages: 437-443
- DOI
  10.1007/s10571-016-0376-x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] Diurnal dynamic behavior of microglia in response to infected bacteria through the UDP-P2Y6 receptor system.2016
- Author(s)
  Takayama F, Hayashi Y, Wu Z, Liu Y, Nakanishi H.
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 30006-30006
- DOI
  10.1038/srep30006
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] BK channels in microglia are required for2016
- Author(s)
  Yoshinori Hayashi, Saori Morinaga, Jing Zhang, Yasushi Satoh, Andrea Meredith, Takahiro Nakata, Zhou Wu, Shinichi Kohsaka, Kazuhide Inoue, Hiroshi Nakanishi
- Journal Title
  
  Nature communications
  
  Volume: 7 Issue: 1 Pages: 11697-11697
- DOI
  10.1038/ncomms11697
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04970, KAKENHI-PUBLICLY-16H01340, KAKENHI-PLANNED-25117009, KAKENHI-PLANNED-25117013, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] An EP2 agonist facilitates NMDA-induced outward currents and inhibits dendritic beading through activation of BK channels in mouse cortical neurons.2016
- Author(s)
  Hayashi Y, Morinaga S, Liu X, Zhang J, Wu Z, Yokoyama T, Nakanishi H
- Journal Title
  
  Mediators Inflamm
  
  Volume: 2016 Pages: 5079597-5079597
- DOI
  10.1155/2016/5079597
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01340, KAKENHI-PROJECT-15H05015, KAKENHI-PROJECT-16H05848, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-16K11477, KAKENHI-PROJECT-16K11478
[Journal Article] Cathepsin D deficiency induces oxidative damage in brain pericytes and impairs the blood-brain barrier2015
- Author(s)
  Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
- Journal Title
  
  Molecular and Cellular Neuroscience
  
  Volume: 64 Pages: 51-60
- DOI
  10.1016/j.mcn.2014.12.002
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-26861555, KAKENHI-PROJECT-15K15684, KAKENHI-PROJECT-15H05015
[Journal Article] BK channel in microglia as a potent therapeutic molecular target for neuropathic pain2015
- Author(s)
  Hayashi Y, Nakanishi H.
- Journal Title
  
  Journal of Oral Biosciences
  
  Volume: * Issue: 3 Pages: 131-134
- DOI
  10.1016/j.job.2015.03.001
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24791979
[Journal Article] Peripheral Role of Cathepsin S in Th1 Cell-Dependent Transition of Nerve Injury-Induced Acute Pain to a Chronic Pain State2014
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinori Hayashi, Ryo Okada, and Hiroshi Nakanishi
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 34 Issue: 8 Pages: 3013-3022
- DOI
  10.1523/jneurosci.3681-13.2014
- Data Source
  KAKENHI-PROJECT-24791979
[Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state2014
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: 34 Pages: 3013-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659827
[Journal Article] A possible link between microglial process dysfunction and neuropsychiatric disorders2014
- Author(s)
  Hayashi Y, Wu Z, Nakanishi H
- Journal Title
  
  Journal of Neurological Disorders & Stroke
  
  Volume: 2 Pages: 1060-1060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24791979
[Journal Article] Autophagy in superficial spinal dorsal horn accelerates the cathepsin B-dependent morphine antinociceptive tolerance2014
- Author(s)
  Yoshinori Hayashi Y, Yuka Koga, Xinwen Zhang, Christoph Peters, Yanagawa Y, Zhou Wu, Takeshi Yokoyama, Hiroshi Nakanishi
- Journal Title
  
  Neuroscience
  
  Volume: 275 Pages: 384-394
- DOI
  10.1016/j.neuroscience.2014.06.037
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24791979
[Journal Article] NMDAレセプターとミクログリア：ミクログリアのシナプス可塑性ならびにシナプス再編への関与特集：NMDAレセプター神経疾患の分子病態を探る2013
- Author(s)
  林　良憲、中西　博
- Journal Title
  
  日本神経精神薬理学雑誌
  
  Volume: 33 Pages: 211-216
- Data Source
  KAKENHI-PROJECT-24791979
[Journal Article] Diurnal Spatial Rearrangement of Microglial Processes through the Rhy thmic Expression of P2Y12 Receptors2013
- Author(s)
  Hayashi Y, Koyanagi S, Kusuno se N, Takayama F, Okada R, Wu Z, Ohdo S, Nakanishi H.
- Journal Title
  
  Journal of Neurological Disorders
  
  Volume: vol.1 Issue: 02 Pages: 121-121
- DOI
  10.4172/2329-6895.1000120
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05694, KAKENHI-PROJECT-24791979
[Journal Article] The intrinsic microglial molecular clock controls synaptic strength via the circadian expression of cathepsin S2013
- Author(s)
  Hayashi Y, Koyanagi S, Kusunose N, Okada R, Wu Z, Tozaki-S aitoh H, Ukai K, Kohsaka S, Inoue K. Ohdo S. Nakanishi H.
- Journal Title
  
  Scientific Reports
  
  Volume: vol.3 Issue: 1 Pages: 1-7
- DOI
  10.1038/srep02744
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J05694, KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-24390149, KAKENHI-PROJECT-24791979, KAKENHI-PLANNED-25117013
[Journal Article] Possible involvement of aiPLA2 in the phosphatidylserine-containing liposomes induced production of PGE2 and PGD2 in microglia2013
- Author(s)
  Fumiko Takayama, Zhou Wu, Hong Ma HM, Okada R, Yoshinori Hayashi, Hiroshi Nakanishi
- Journal Title
  
  J Neuroimmunol
  
  Volume: 262 Issue: 1-2 Pages: 121-124
- DOI
  10.1016/j.jneuroim.2013.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
[Journal Article] Peripheral role of cathepsin S in Th1 cell-dependent transition of nerve injury-induced acute pain to a chronic pain state2013
- Author(s)
  Xinwen Zhang, Zhou Wu, Yoshinoru Hayashi, Ryo Okada R, Hiroshi Nakanishi
- Journal Title
  
  J Neurosci
  
  Volume: 34 Pages: 3013-3022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416
[Journal Article] Differential pathways for interleukin-1b production activated by chromogranin A and amyloid β in microglia2013
- Author(s)
  Zhou Wu, Li Sun, Sadayuki Hashioka, Yu S, Schwab C, Ryo Okada, Yoshinori Hayashi, Patrick L McGeer PL, Hiroshi Nakanishi
- Journal Title
  
  Neurobiol Aging
  
  Volume: 34 Issue: 12 Pages: 2715-2725
- DOI
  10.1016/j.neurobiolaging.2013.05.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827, KAKENHI-PROJECT-24791979
[Journal Article] Microglia and synaptic reorganization: focus on the movement and functions of microglial processes2013
- Author(s)
  林　良憲、中西　博
- Journal Title
  
  Folia Pharmacologica Japonica
  
  Volume: 142 Issue: 5 Pages: 231-235
- DOI
  10.1254/fpj.142.231
- NAID
  130003382527
- ISSN
  0015-5691, 1347-8397
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-24791979
[Journal Article] Age-dependent neuroinflammatory responses and deficits in long-term potentiation in the hippocampus during systemic inflammation2012
- Author(s)
  Liu X, Wu Z, Hayashi Y, Nakanishi H
- Journal Title
  
  Neuroscience
  
  Volume: 216 Pages: 133-142
- DOI
  10.1016/j.neuroscience.2012.04.050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Journal Article] Microglial Cathepsin B Contributes to the Initiation of Peripheral Inflammation-induced Chronic Pain.2012
- Author(s)
  S. Li, Z. Wu, Y. Hayashi, C. Peters, K. Inoue, M. Tsuda, and H. Nakanishi.
- Journal Title
  
  J.Neurosci.
  
  Volume: 32(33) Issue: 33 Pages: 11330-42
- DOI
  10.1523/jneurosci.0677-12.2012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23229008, KAKENHI-PROJECT-24390416, KAKENHI-PROJECT-24592802, KAKENHI-PROJECT-24659827
[Presentation] Microglial MCH-class I contributes to orofacial neuropathic pain2022
- Author(s)
  林　良憲，篠田雅路
- Organizer
  第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会合同大会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] 雌における新生児期外傷後のアロディニア長期化に対する三叉神経脊髄路核尾側亜核のPPARγの役割2022
- Author(s)
  尾辻盛，林良憲，人見涼露，岩田幸一，篠田雅路
- Organizer
  第27回日本口腔顔面痛学会学術大会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] IL-33 dependent facilitation of glutamatergic neurotransmission in the Vc causes orofacial neuropathic pain2022
- Author(s)
  Yoshinori Hayashi, Yuki Kimura, Masamichi Shinoda
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] Roles of pannexin 1 in the trigeminal ganglion in orofacial mechanical allodynia following infraorbital nerve injury in rats2022
- Author(s)
  栗栖諒子，三枝禎，青野悠里，林良憲，人見涼露，前田茂，嶋田昌彦，岩田幸一，篠田雅路
- Organizer
  第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会合同大会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] Macrophage-Schwann cell communication promotes peripheral nerve regeneration2022
- Author(s)
  大島絵莉，林　良憲，篠田雅路
- Organizer
  第96回日本薬理学会年会/第43回日本臨床薬理学会学術総会合同大会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] Complement C1q contributes to orofacial pain through astrocytic IL-1β in the trigeminal spinal subnucleus caudalis2022
- Author(s)
  Hong Chaoli，林良憲，人見涼露，岩田幸一，篠田雅路
- Organizer
  第27回日本口腔顔面痛学会学術大会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] IL-33 dependent facilitation of glutamatergic neurotransmission in the Vc causes orofacial neuropathic pain2022
- Author(s)
  林　良憲、木村有貴、篠田雅路
- Organizer
  第95回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] 三叉神経脊髄路核尾側亜核におけるIL-33-Fyn経路によるGluN2Bのリン酸化を介した口腔顔面領域の神経障害性疼痛の発症メカニズム2021
- Author(s)
  木村有貴、林良憲、篠田雅路
- Organizer
  第26回日本口腔顔面痛学会学術大会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] オリゴデンドロサイトの産生するIL-33はFyn依存的なGluN2Bのリン酸化を介して口腔顔面領域神経障害性疼痛を促進する2021
- Author(s)
  木村有貴、林良憲、篠田雅路
- Organizer
  第63回基礎歯科医学会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] In vivo conversion from microglia/macrophages to neurons reinstates neurological function after ischemic injury2021
- Author(s)
  Takashi Irie, Taito Matsuda, Yoshinori Hayashi, Jun-ichi Kira, Kinichi Nakashima
- Organizer
  2021 Asian Oceanian Congress of Neurology
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] Neutrophil-neuron crosstalk induces mechanical allodynia in experimental autoimmune encephalomyelitis2021
- Author(s)
  林　良憲
- Organizer
  第126回日本解剖学会総会・全国学術集会、第98回日本生理学会大会　合同大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] IL-33-mediated neuronal sensitization in the trigeminal spinal nucleus caudalis is required for the development of orofacial neuropathic pain2021
- Author(s)
  林　良憲、木村有貴、篠田雅路
- Organizer
  第43回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] In vivo conversion from microglia to neurons reinstates neurological function after ischemic injury2020
- Author(s)
  Takashi Irie, Taito Matsuda, Yoshinori Hayashi, Jun-ichi Kira, Kinichi Nakashima
- Organizer
  第43回日本神経科学会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] 口腔顔面領域における神経障害性疼痛に対する活性型グリア細胞に発現するIFNγの関与2020
- Author(s)
  岡田明子、淺野早哉香、篠田雅路、林良憲、岩田幸一、今村佳樹
- Organizer
  第42回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] グリア間の相互作用に基づいた神経障害性疼痛の発症メカニズムの解明2020
- Author(s)
  淺野　早哉香、林　良憲、岡田　明子、岩田　幸一、篠田　雅路、今村　佳樹
- Organizer
  第25回日本口腔顔面痛学会
- Data Source
  KAKENHI-PROJECT-20K09896
[Presentation] カテプシンE依存的に好中球で産生されるエラスターゼが実験的自己免疫性脳脊髄炎で生じる痛みに関与する2019
- Author(s)
  原田ゆか，中西　博，林　良憲
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] Neuroimmune interaction in the dorsal root ganglion induces mechanical allodynia in experimental autoimmune encephalomyelitis.2019
- Author(s)
  Yoshinori Hayashi
- Organizer
  内藤コンファレンス
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] ミクログリアのchannelopathyがもたらす痛みの慢性化機構の解明基礎シンポジウム「知っておきたい痛みのメカニズム」2019
- Author(s)
  林　良憲
- Organizer
  第24回日本口腔顔面痛学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] ミクログリアKCNMB3による神経障害性疼痛の制御2019
- Author(s)
  今利一寿，石井広太郎，矢内雄太，大山順子，熊丸　渉，森悦秀，林　良憲
- Organizer
  第23回口腔顔面神経機能学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] 脊髄ミクログリアBKチャネルの神経障害性疼痛における役割2019
- Author(s)
  佐藤泰司、諸橋徹、林良憲、板倉沙也子、川口慎憲、中西博、メレディスアンドレア、石塚俊晶
- Organizer
  第92回日本薬理学会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] マウスにおける神経幹細胞特異的ITPA欠損は神経細胞の脱分極を引き起こし，てんかん性発作と早期死亡の原因となる2019
- Author(s)
  土本大介，古賀祐一郎，林良憲，アボルハッサニノナ，米嶋康臣，作見邦彦，中西博，豊國伸哉，中別府雄作
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] 好中球と神経の双方向性作用に基づいた痛みの発症メカニズム2019
- Author(s)
  林　良憲
- Organizer
  次世代薬理学セミナー2019 in 那覇，日本薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] Neuroimmune interaction in the dorsal root ganglion induces mechanical allodynia in experimental autoimmune encephalomyelitis.2019
- Author(s)
  Yoshinori Hayashi
- Organizer
  Neuro2019
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] Neuroimmune interaction in the dorsal root ganglion induces mechanical allodynia in experimental autoimmune encephalomyelitis2019
- Author(s)
  Yoshinori Hayashi, Masamichi Shinoda, Koichi Iwata
- Organizer
  8th Asian Pain Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] カテプシンE依存的に好中球で産生されるエラスターゼが実験的自己免疫性脳脊髄炎で生じる痛みに関与する2019
- Author(s)
  原田ゆか、中西　博、林　良憲
- Organizer
  第92回日本薬理学会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] ミクログリアからニューロンへの直接分化転換による脳梗塞後の神経機能回復2019
- Author(s)
  入江剛史，松田泰斗，林良憲，吉良潤一，中島欽一
- Organizer
  第42回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] Direct conversion of microglia into neurons improves neurological recovery after ischemic injury.2019
- Author(s)
  Takashi Irie, Taito Matsuda, Yoshinori Hayashi, Jun-ichi Kira, Kinichi Nakashima
- Organizer
  SfN Neuroscience2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] 脊髄ミクログリアBKチャネルの神経障害性疼痛における役割2019
- Author(s)
  佐藤泰司，諸橋徹，林良憲，板倉沙也子，川口慎憲，中西博，メレディスアンドレア，石塚俊晶
- Organizer
  第92回日本薬理学会年会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] ミクログリアのイオンチャネルの機能異常に基づいた神経障害性疼痛のメカニズム2019
- Author(s)
  林　良憲，篠田雅路，岩田幸一
- Organizer
  第13回三叉神経領域の感覚-運動統合研究会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] 実験的自己免疫性脳脊髄炎に伴う痛みはDRGに集積した好中球で発現誘導されるカテプシンEによって生じる2018
- Author(s)
  原田ゆか、中西　博、林　良憲
- Organizer
  第40回日本疼痛学会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] Neural stem cell-specific Itpa knockout mouse as a model of human ITPA deficiency2018
- Author(s)
  Tsuchimoto D, Koga Y, Hayashi Y, Abolhassani N, Yoneshima Y, Nakanishi H, Nakabeppu Y
- Organizer
  第41回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] 実験的自己免疫性脳脊髄炎におけるカテプシンEがもたらす免疫感覚異常2018
- Author(s)
  林　良憲
- Organizer
  第2回感覚免疫学研究会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] Neural stem cell-specific Itpa knockout mouse as a model of human epileptic encephalopathy caused by ITPA deficiency2018
- Author(s)
  Tsuchimoto D, Koga Y, Hayashi Y, Abolhassani N, Yoneshima Y, Nakanishi H, Nakabeppu Y
- Organizer
  The Joint Symposium of the 13th International Symposium of the Institute Network for Biomedical Sciences and the 28th Hot Spring Harbor International Symposium
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] 痛みの慢性化スイッチとしてのケラチノサイトの新たな役割2017
- Author(s)
  林　良憲
- Organizer
  第59回歯科基礎医学会学術大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] カテプシンによる感覚情報の制御メカニズムの解明2017
- Author(s)
  林　良憲
- Organizer
  第39会日本疼痛学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] カテプシン依存的なプロテオリシスによる感覚情報の制御メカニズム2017
- Author(s)
  林　良憲
- Organizer
  第40回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] ミクログリアBKチャネルを介したモルヒネ誘発性疼痛過敏の形成メカニズム2016
- Author(s)
  林　良憲、中西　博
- Organizer
  Japan Purine Club2016
- Place of Presentation
  東京慈恵会医科大学
- Year and Date
  2016-10-26
- Data Source
  KAKENHI-PROJECT-16K11477
[Presentation] A big channel in small glia as a promising molecular target for the treatment of opioid-induced hyperalgesia2015
- Author(s)
  林　良憲、中西　博
- Organizer
  第120回日本解剖学会総会、第92回日本生理学会大会　合同大会
- Place of Presentation
  神戸国際会議場
- Year and Date
  2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] カテプシンSは告げんの日無い変化がもたらすミクログリアならびにニューロン機能の日内変化2014
- Author(s)
  高山扶美子、林　良憲、武　洲、中西　博
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学ラマツィーニホール（福岡）
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  第19回グリア研究会
- Place of Presentation
  東京商工会議所
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] Involvement of cathepsin S in the diurnal morphological and functional changes of cortical microglial processes2014
- Author(s)
  高山扶美子、林良憲、武洲、中西博
- Organizer
  第21回日本時間生物学会学術大会
- Place of Presentation
  九州大学医学部百年講堂（福岡）
- Year and Date
  2014-11-07
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  研究会　「痛みと痛覚情動連関の神経機構」
- Place of Presentation
  生理学研究所（岡崎）
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] 神経障害性疹痛の慢性化におけるカテプシンSの役割2014
- Author(s)
  張馨文、武洲、林良憲、中西博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Year and Date
  2014-03-19
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  第19回グリア研究会
- Place of Presentation
  東京商工会議所（東京）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  第67回日本薬理学会西南部会
- Place of Presentation
  産業医科大学ラマツィーニホール（福岡）
- Year and Date
  2014-11-23
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアBKチャネルを介したモルヒネ鎮痛耐性及び痛覚過敏メカニズム解明2014
- Author(s)
  林　良憲、中西　博
- Organizer
  生理学研究所　研究会「痛みと痛覚情動連関の神経機構」
- Place of Presentation
  生理学研究所
- Year and Date
  2014-12-11
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] クログリアの2種類の突起の日内変化に関する形態学的ならびに生体イメージング解析2014
- Author(s)
  髙山扶美子、林良憲、武洲、中西博
- Organizer
  第56回歯科基礎医学会学術大会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-09-26
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] BKチャネルを介した疼痛制御機構の解明2014
- Author(s)
  林　良憲
- Organizer
  第56回歯科基礎医学会学術大会・総会
- Place of Presentation
  福岡国際センター
- Year and Date
  2014-09-27
- Invited
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] Microglial circadian clock controls microglia-synapse interactions in the healthy brain2013
- Author(s)
  林　良憲, 中西　博
- Organizer
  第86回日本薬理学会年会、シンポジウム：Roles of microglia and astrocytes in synaptic reotganization: New trends in glial research
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Regu1ation of microg1ia-synapse interactions and synaptic strength by microg1ia1 circadian c1ock,in Symposium of"Ro1es of microg1ia and astrocytes in synaptic reorganization : New trends in g1ia1 research"2013
- Author(s)
  林良憲,中西博
- Organizer
  シンポジウム,第86回日本薬理学会年会
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] Regulation of microglia-synapse interactions and synaptic strength by microglial circadian clock2013
- Author(s)
  林　良憲、中西　博
- Organizer
  第86回日本薬理学会年会
- Place of Presentation
  福岡国際会議場（福岡）
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] Regulation of microglia-synapse interactions and synaptic strength by microglial circadian clock2013
- Author(s)
  林良憲, 中西博
- Organizer
  第86回日本薬理学会年会、シンポジウム : Roles of microglia and astrocytes in synaptic reotganization : New trends in glial research
- Place of Presentation
  福岡(招待講演)
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリア時計遺伝子による神経活動の調節の解明2012
- Author(s)
  林　良憲、武　洲、中西　博
- Organizer
  第54回歯科基礎医学会学術大会・総会
- Place of Presentation
  奥羽大学　記念講堂（福島）
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] Active Regulation of Synaptic Strength by the Circadian Rhythmicity through the Microglial P2Y Receptor.2012
- Author(s)
  林　良憲、武　洲、中西　博
- Organizer
  Purine 2012
- Place of Presentation
  Centennial Hall Kyushu University（福岡）
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] NMDAレセプターとミクログリア2012
- Author(s)
  中西博,林良憲
- Organizer
  CINP・NP20l2合同年会,シンポジウム: NMDAレセプター神経疾患の分子病態を探る
- Place of Presentation
  宇都宮
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] A big channel in small glia as a promising molecular target for the treatment of opioid-induced hyperalgesia
- Author(s)
  林　良憲、中西　博
- Organizer
  第120回日本解剖学会総会・第92回日本生理学会大会
- Place of Presentation
  神戸国際会議場（神戸）
- Year and Date
  2015-03-21 – 2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] Novel analgesic mechanism of S-ketamine on the neuropathic pain through the microglial Ca2+-activated K+ channel
- Author(s)
  林良憲, 中西博
- Organizer
  Neuroscience 2013 Society for Neuroscience
- Place of Presentation
  San Diego
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] ミクログリアのカテプシンS発現リズムによるシナプス強度の調節機構の解明
- Author(s)
  林良憲, 小柳悟, 楠瀬直喜, 岡田亮, 武洲, 齊藤秀俊, 高坂新一, 井上和秀, 大戸茂弘, 中西博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24659827
[Presentation] ミクログリア内在性分子時計はカテプシンS発現リズムを介して大脳皮質ニューロンのシナプス活動を調節する
- Author(s)
  林良憲, 小柳悟, 楠瀬直喜, 岡田亮, 武洲, 齊藤秀俊, 大戸茂弘, 高坂新一, 井上和秀, 中西博
- Organizer
  グリア研究会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] 神経障害性疼痛の慢性化におけるカテプシンSの役割
- Author(s)
  張　馨文、武　洲、林　良憲、中西　博
- Organizer
  第87回日本薬理学会年会
- Place of Presentation
  仙台国際センター
- Data Source
  KAKENHI-PROJECT-24390416
[Presentation] ミクログリアにおけるカテプシンSの発現リズムによるシナプス強度の調節
- Author(s)
  林良憲, 岡田亮, 武洲, 中西博
- Organizer
  基礎歯科医学会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-24791979
[Presentation] ミクログリア内在性分子時計による大脳皮質ニューロンのシナプス活動の調節機構
- Author(s)
  林良憲
- Organizer
  第4回福岡薬理・生理系研究会
- Place of Presentation
  九州大学コラボステーション
- Data Source
  KAKENHI-PROJECT-24791979

1. SHINODA Masamichi (20362238)

# of Collaborated Projects: 6 results

# of Collaborated Products: 27 results
2. 人見涼露 (70548924)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
3. 岩田幸一 (60160115)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
4. HIROSHI Nakanishi (20155774)

# of Collaborated Projects: 2 results

# of Collaborated Products: 28 results
5. SHIBUTA Ikuko (60459906)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. TAKE Hiro (10420598)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
7. 久保亜抄子 (70733202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 三枝禎 (50277456)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 小野堅太郎 (40316154)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 水田健太郎 (40455796)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 藤内祝 (50172127)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 光藤健司 (70303641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 野間昇 (70386100)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 中井淳一 (80237198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SUZUKI Ikuko

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. KATSURABAYASHIYASH Shutaro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. SATOH Yasushi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 豊福明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 藤田智史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 倪軍軍

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 浦田健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
22. 丸山健太

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 井上和秀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 深谷親

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 今村佳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 小川明子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 坪井美行

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAYASHI Yoshinori 林 良憲

Research Projects

Research Products

Co-Researchers

Role of satellite cells in trigeminal ganglion in psychosocial stress-induced orofacial pain

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三叉神経節ニューロンの新たな可塑性の獲得様式の同定による神経障害性疼痛の解明Principal Investigator

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Elucidation of a new molecular mechanism of oral cancer pain based on plastic changes in the intercellular network in the trigeminal ganglion

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Fundamental study of the development of new therapy for the treatment of anticancer drug-induced persistent pain targeting glial cell activation

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Orofacial pain mechanism due to infant stress

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Discovery of novel pain markers in projection neuronsPrincipal Investigator

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Macrophages in trigeminal ganglion contributes to the ectopic orofacial pain following inferior alveolar nerve injury

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Therapeutic mechanisms of chronic pain by dental pulp stem cellsPrincipal Investigator

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Critical roles of the chromogranin A-cathepsin B system in a transition of acute pain to a chronic pain state

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Involvement of endosomal Toll-like receptors in the development of neuropathic pain

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Novel role of microglial BK channels on chronic painPrincipal Investigator

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[Book] NMDAレセプターとミクログリア：ミクログリアのシナプス可塑性ならびにシナプス再編への関与2013

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[Book] BK+ Channels Contributes to the Cellular Activation of Microglia: A big Channel in Small Glia2013

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HAYASHI Yoshinori 林良憲