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Hirano Minako  平野 美奈子

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HIRANO Minako  平野 美奈子

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Researcher Number 80585167
Other IDs
Affiliation (Current) 2025: 岡山大学, ヘルスシステム統合科学学域, 准教授
Affiliation (based on the past Project Information) *help 2025: 岡山大学, ヘルスシステム統合科学学域, 准教授
2022 – 2023: 岡山大学, ヘルスシステム統合科学学域, 准教授
2014 – 2021: 光産業創成大学院大学, 光産業創成研究科, 講師
2012 – 2013: 光産業創成大学院大学, その他の研究科, 講師
2012: 独立行政法人理化学研究所, 細胞動態計測研究グループ, 客員研究員
2011: 独立行政法人理化学研究所, 細胞動態計測研究グループ, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 43040:Biophysics-related / Biophysics / Biological Sciences
Keywords
Principal Investigator
イオンチャネル / 光遺伝学 / オプトジェネティクス / 光感受性 / 蛍光色素 / 1分子計測 / 光感受性蛋白質 / 構造機能相関 / 光感受性タンパク質 / 光感受能 … More / イオン環境 / 生物物理学 / 光制御 / イメージング / 分子計測 / 全反射顕微鏡 Less
  • Research Projects

    (7 results)
  • Research Products

    (52 results)
  • Co-Researchers

    (1 People)
  •  イオンチャネル標的薬の発見・評価のための高効率・高精度な活性測定系の確立Principal Investigator

    • Principal Investigator
      平野 美奈子
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Okayama University
  •  光活性化cAMP産生酵素の高時間分解能活性計測を基盤とした光遺伝学ツールの創製Principal Investigator

    • Principal Investigator
      平野 美奈子
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Okayama University
  •  Creaton of photo-activated ion channel for regulating intracellular ionic environment by lightPrincipal Investigator

    • Principal Investigator
      Hirano Minako
    • Project Period (FY)
      2018 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Okayama University
      The Graduate School for the Creation of New Photonics Industries
  •  Creating light-activated ion channels for regulating cell functions by lightPrincipal Investigator

    • Principal Investigator
      Hirano Minako
    • Project Period (FY)
      2015 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      The Graduate School for the Creation of New Photonics Industries
  •  Engineering of photo-activated ion channelsPrincipal Investigator

    • Principal Investigator
      Hirano Minako
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      The Graduate School for the Creation of New Photonics Industries
  •  蛍光色素を利用したイオンチャネルの開閉機構の可視化Principal Investigator

    • Principal Investigator
      平野 美奈子
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The Graduate School for the Creation of New Photonics Industries
      The Institute of Physical and Chemical Research
  •  A study on ion-channel gating by single molecule measurement and manipulation.Principal Investigator

    • Principal Investigator
      HIRANO Minako
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      The Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018 2016 2015 2014 2013 2012 2011

All Journal Article Presentation Patent

  • [Journal Article] Development of an automated system to measure ion channel currents using a surface-modified gold probe.2021

    • Author(s)
      Minako Hirano, Masahisa Tomita, Chikako Takahashi, Nobuyuki Kawashima and Toru Ide
    • Journal Title

      Scientific reports

      Volume: 11(1) Issue: 1 Pages: 17934-17934

    • DOI

      10.1038/s41598-021-97237-z

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06157, KAKENHI-PROJECT-18K06168
  • [Journal Article] A Lipid Bilayer Formed on a Hydrogel Bead for Single Ion Channel Recordings2020

    • Author(s)
      Hirano Minako、Yamamoto Daiki、Asakura Mami、Hayakawa Tohru、Mise Shintaro、Matsumoto Akinobu、Ide Toru
    • Journal Title

      Micromachines

      Volume: 11 Issue: 12 Pages: 1070-1070

    • DOI

      10.3390/mi11121070

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06157, KAKENHI-PROJECT-18K06168, KAKENHI-PROJECT-18K05675
  • [Journal Article] The C-terminal region affects the activity of photoactivated adenylyl cyclase from Oscillatoria acuminata2019

    • Author(s)
      Minako Hirano, Masumi Takebe, Tomoya Ishido, Toru Ide, Shigeru Matsunaga
    • Journal Title

      Scientific Reports

      Volume: 9 Issue: 1 Pages: 20262-20262

    • DOI

      10.1038/s41598-019-56721-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Journal Article] Electrostatic state of the cytoplasmic domain influences inactivation at the selectivity filter of the KcsA potassium channel.2019

    • Author(s)
      Minako Hirano, Toru Ide
    • Journal Title

      Biochimica et Biophysica Acta (BBA) - Biomembranes

      Volume: 1861(1) Issue: 1 Pages: 220-227

    • DOI

      10.1016/j.bbamem.2018.07.011

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K06157, KAKENHI-PROJECT-15K07035
  • [Journal Article] A single amino acid gates the KcsA channel.2014

    • Author(s)
      Hirano, M, Okuno, D, Onishi, Y, Ide, T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 450(4) Issue: 4 Pages: 1537-1540

    • DOI

      10.1016/j.bbrc.2014.07.032

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370059, KAKENHI-PROJECT-25840055
  • [Journal Article] Uncovering the Protein Translocon at the Chloroplast Inner Envelope Membrane2013

    • Author(s)
      Shingo Kikuchi
    • Journal Title

      SCIENCE

      Volume: 339 Issue: 6119 Pages: 571-574

    • DOI

      10.1126/science.1229262

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-22020024, KAKENHI-PROJECT-22370059, KAKENHI-PROJECT-23770190, KAKENHI-PROJECT-24657073, KAKENHI-PROJECT-24657110, KAKENHI-PUBLICLY-23113519, KAKENHI-PUBLICLY-24117511
  • [Journal Article] Automated Parallel Recordings of Topologically Identified Single Ion Channels.2013

    • Author(s)
      Kawano R, Tsuji Y, Sato K, Osaki T, Kamiya K, Hirano M, Ide T, Miki N, Takeuchi S.
    • Journal Title

      Scientific Reports

      Volume: 3 Issue: 1 Pages: 1955-1955

    • DOI

      10.1038/srep01995

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22370059, KAKENHI-PROJECT-24655072, KAKENHI-PROJECT-24657110, KAKENHI-PROJECT-25246017, KAKENHI-PROJECT-25840055
  • [Journal Article] 「ちから」でイオンチャネルの機能を制御する2012

    • Author(s)
      井出 徹、平野 美奈子、奥野 大地
    • Journal Title

      生物物理学会誌

      Volume: 52(6) Pages: 289-290

    • NAID

      10031126103

    • Data Source
      KAKENHI-PUBLICLY-23113519
  • [Journal Article] 「ちから」でイオンチャネルの機能を制御する2012

    • Author(s)
      井出徹、平野美奈子、奥野大地
    • Journal Title

      生物物理学会誌

      Volume: 52(6) Pages: 289-290

    • NAID

      10031126103

    • URL

      https://www.jstage.jst.go.jp/article/biophys/52/6/52_289/_pdf

    • Data Source
      KAKENHI-PROJECT-23770190
  • [Journal Article] Role of the KcsA channel cytoplasmic domain in pH-dependent gating2011

    • Author(s)
      M. Hirano, Y. Onishi, T. Yanagida, T. Ide
    • Journal Title

      Biophysical Journal

      Volume: 101 Pages: 2157-2162

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Journal Article] Direct Manipulation of a Single Potassium Channel Gate with an Atomic Force Microscope Probe2011

    • Author(s)
      M.Kitta, T.Ide, M.Hirano, H.Tanaka, T.Yanagida, T.Kawai
    • Journal Title

      Small

      Volume: 7(16) Issue: 16 Pages: 2379-2383

    • DOI

      10.1002/smll.201002337

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370059, KAKENHI-PUBLICLY-23113519, KAKENHI-PROJECT-23770190
  • [Journal Article] The role of the KcsA channel cytoplasimic domain in pH-dependent gating2011

    • Author(s)
      M.Hirano, Y.Onishi, T.Yanagida, T.Ide
    • Journal Title

      Biophysical Journal

      Volume: 101(9) Issue: 9 Pages: 2157-2162

    • DOI

      10.1016/j.bpj.2011.09.024

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370059, KAKENHI-PUBLICLY-23113519, KAKENHI-PROJECT-23770190
  • [Journal Article] Channels formed by amphotericin B covalent dimers exhibit rectification2011

    • Author(s)
      M.Hirano, Y.Takeuchi, N.Matsumori, M.Murata, T.Ide
    • Journal Title

      J Membr Biol

      Volume: 240 Issue: 3 Pages: 159-164

    • DOI

      10.1007/s00232-011-9354-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22370059, KAKENHI-PUBLICLY-23113519
  • [Patent] 光活性化アデニル酸シクラーゼ2019

    • Inventor(s)
      平野 美奈子、松永 茂、建部 益美
    • Industrial Property Rights Holder
      浜松ホトニクス株式会社、学校法人光産業創成大学院大学
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2019-129374
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] Novel ion channel activity measurement system for drug screening2024

    • Author(s)
      Minako Hirano
    • Organizer
      The 15th international symposium for future technology creating better human health and society
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K06173
  • [Presentation] Development of channel current measurement device using agarose gel beads2023

    • Author(s)
      Mami Asakura, Shuyan Wang, Minako Hirano, Toru Ide
    • Organizer
      第61回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-22K06173
  • [Presentation] Identification of Key Amino Acids affecting the Activity of Photoactivated Adenylyl Cyclase from Oscillatoria acuminata2023

    • Author(s)
      Minako Hirano, Masumi Takebe, Syunshi Yano, Hinase Kondo, Ayu Yuasa, Toru Ide
    • Organizer
      第61回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-22K06173
  • [Presentation] Development of a simple single-channel current measurement system2023

    • Author(s)
      Tomomi Murata, Toru Ide, Minako Hirano, Mami Asakura
    • Organizer
      第61回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-22K06173
  • [Presentation] 光活性化アデニル酸シクラーゼの活性制御機構の理解に向けた研究・開発2022

    • Author(s)
      平野美奈子、建部益美、北村有希、三好佑奈、井出徹
    • Organizer
      第45回日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] Structural changes of adenylate cyclase from Oscillatoria acumminata in response to blue light stimulation2022

    • Author(s)
      北村有希、井出徹、平野美奈子
    • Organizer
      第60回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] 光活性化アデニル酸シクラーゼの活性制御機構の理解に向けた研究・開発2022

    • Author(s)
      平野美奈子、建部益美、北村有希、三好佑奈、井出徹
    • Organizer
      第45回 日本分子生物学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K06173
  • [Presentation] 光活性化アデニル酸シクラーゼの活性化に伴う構造変化の解明2022

    • Author(s)
      北村有希、井出徹、平野美奈子
    • Organizer
      第60回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-22K06173
  • [Presentation] アガロースゲルビーズを用いた人工膜チャネル電流測定2022

    • Author(s)
      朝倉真実、椋野敦弥、平野美奈子、井出徹
    • Organizer
      第60回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-22K06173
  • [Presentation] Development of an automated system for measuring channel currents using a gold probe2021

    • Author(s)
      平野 美奈子, 富田 正久, 髙橋 稚佳子, 川島 信幸, 井出 徹
    • Organizer
      第59回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] Development of a system for automated ionic current measurement2020

    • Author(s)
      平野 美奈子, 富田 正久, 髙橋 稚佳子, 川島 信幸, 井出 徹
    • Organizer
      第58回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] Identification of the activity-regulating site in the photoactivated adenylate cyclase (OaPAC)2019

    • Author(s)
      Minako Hirano, Tomoya Ishido, Masumi Takebe, Toru Ide, Shigeru Matsunaga
    • Organizer
      第57回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] Light-dependent structural states of OaPAC2019

    • Author(s)
      Tomoya Ishido, Toru Ide, Minako Hirano
    • Organizer
      第57回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] Modifications of K+ channel property2018

    • Author(s)
      Tomoya Ishido, Toru Ide, Minako Hirano
    • Organizer
      第56回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-18K06168
  • [Presentation] Modifications of K+ channel property2018

    • Author(s)
      Tomoya Ishido, Toru Ide, Minako Hirano
    • Organizer
      第56回 日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-15K07035
  • [Presentation] Effects of the electrostatic state of the cytoplasmic domain in the KcsA channel on its gating2016

    • Author(s)
      Minako Hirano, Toru Ide
    • Organizer
      第54回 日本生物物理学会
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-25
    • Data Source
      KAKENHI-PROJECT-15K07035
  • [Presentation] The cytoplasmic domain regulates inactivation in the KcsA channel2015

    • Author(s)
      Minako Hirano, Daichi Okuno, Yukiko Onishi, Toru Ide
    • Organizer
      第53回 日本生物物理学会
    • Place of Presentation
      金沢大学・角間キャンパス
    • Year and Date
      2015-09-14
    • Data Source
      KAKENHI-PROJECT-25840055
  • [Presentation] The cytoplasmic domain regulates inactivation in the KcsA channel2015

    • Author(s)
      Minako Hirano, Daichi Okuno, Yukiko Onishi, Toru Ide
    • Organizer
      第53回 日本生物物理学会
    • Place of Presentation
      金沢大学・角間キャンパス
    • Year and Date
      2015-09-14
    • Data Source
      KAKENHI-PROJECT-15K07035
  • [Presentation] Modifications of ion channel function2014

    • Author(s)
      Minako Hirano, Daichi Okuno, Yukiko Onishi, Hiroaki Yokota, Toru Ide
    • Organizer
      第52回 日本生物物理学会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2014-09-27
    • Data Source
      KAKENHI-PROJECT-25840055
  • [Presentation] Coordination between the cytoplasmic domain and the inactivation gate in the KcsA channel2013

    • Author(s)
      M. Hirano, Y. Onishi, D. Okuno, T. Ide
    • Organizer
      第51回 日本生物物理学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-25840055
  • [Presentation] Reconstitution of ion channel immobilized on solid support into lipid bilayer2013

    • Author(s)
      D. Okuno, M. Hirano, Y. Onishi, T. Ide
    • Organizer
      第51回 日本生物物理学会
    • Place of Presentation
      国立京都国際会館
    • Data Source
      KAKENHI-PROJECT-25840055
  • [Presentation] The KcsA channel cytoplasmic domain effects on the inactivation gating2013

    • Author(s)
      M. Hirano, Y. Onishi, D. Okuno, T. Ide
    • Organizer
      Biophysical Society 57th Annual Meeting
    • Place of Presentation
      フィラデルフィア(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] The KcsA channel cytoplasmic domain effects on the inactivation gating2013

    • Author(s)
      M. Hirano, Y. Onishi, D. Okuno, T. Ide
    • Organizer
      Biophysical Society 57th Annual Meeting
    • Place of Presentation
      フィラデルフィア(アメリカ合衆国)
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] The KcsA channel cytoplasmic domain effects on the inactivation gating2012

    • Author(s)
      M. Hirano, Y. Onishi, D. Okuno, T. Ide
    • Organizer
      第50回 日本生物物理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-23
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] Single molecule imaging of bio-molecules2012

    • Author(s)
      T. Ide, M. Hirano, D. Okuno
    • Organizer
      The 14th Takayanagi Kenjiro Memorial Symposium
    • Place of Presentation
      静岡
    • Year and Date
      2012-11-28
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] The KcsA channel cytoplasmic domain effects on the inactivation gating2012

    • Author(s)
      M. Hirano, Y. Onishi, D. Okuno, T. Ide
    • Organizer
      第50回 日本生物物理学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PUBLICLY-23113519
  • [Presentation] The KcsA channel cytoplasmic domain effects on the inactivation gating2012

    • Author(s)
      M. Hirano, Y. Onishi, D. Okuno, T. Ide
    • Organizer
      第50回 日本生物物理学会
    • Place of Presentation
      名古屋
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] Automated drug screening system for ion channel proteins using artificial cell membranes2012

    • Author(s)
      R. Kawano, Y. Tuji, K. Kimiya, T. Osaki, M. Hirano, T. Ide, N. Miki, S.Takeuchi
    • Organizer
      第50回 日本生物物理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-24
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] Reconstitution of ion channel into lipid bilayer using glass needle2012

    • Author(s)
      D. Okuno, M. Hirano, Y. Onishi, T. Yanagida, T. Ide
    • Organizer
      第50回 日本生物物理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-24
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] The KcsA channel cytoplasmic domain effects on the inactivation gating2012

    • Author(s)
      M. Hirano, Y. Onishi, D. Okuno, T. Ide
    • Organizer
      Molecular Science of Fluctuations toward Biological Functions, The 6th International Symposium
    • Place of Presentation
      京都
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] Mechanism for opening and closing by the KcsA channel2011

    • Author(s)
      平野美奈子
    • Organizer
      第49回 日本生物物理学会
    • Place of Presentation
      兵庫県立大学
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] 蛍光色素を利用したイオンチャネルの開閉機構の可視化2011

    • Author(s)
      平野美奈子
    • Organizer
      新学術領域研究「細胞機能と分子活性の多次元蛍光生体イメージング」第1回研究代表者会議
    • Place of Presentation
      北海道大学(北海道)
    • Year and Date
      2011-06-30
    • Data Source
      KAKENHI-PUBLICLY-23113519
  • [Presentation] The KcsA channel opening and closing mechanism2011

    • Author(s)
      M. Hirano
    • Organizer
      QBiC Retreat 2011: How to achieve "Whole Cell Modeling"
    • Place of Presentation
      兵庫
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] Mechanism for opening and closing by the KcsA channel2011

    • Author(s)
      Minako Hirano
    • Organizer
      QBiC Retreat 2011: How to achieve "Whole Cell Modeling"
    • Place of Presentation
      ユニトピアささやま
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] 蛍光色素を利用したイオンチャネルの開閉機構の可視化2011

    • Author(s)
      平野美奈子
    • Organizer
      新学術領域研究「細胞機能と分子活性の多次元蛍光生体イメージング」第1回研究代表者会議
    • Place of Presentation
      北海道大学
    • Data Source
      KAKENHI-PROJECT-23770190
  • [Presentation] The KcsA channel opening and closing mechanism2011

    • Author(s)
      Minako Hirano
    • Organizer
      QBiC Retreat 2011 : How to achieve "Whole Cell Modeling"
    • Place of Presentation
      ゆにとぴあ篠山(兵庫県)
    • Year and Date
      2011-09-10
    • Data Source
      KAKENHI-PUBLICLY-23113519
  • [Presentation] Mechanism for opening and closing by the KcsA channel2011

    • Author(s)
      M.Hirano. Y.Onishi, T.Yanagida, T.Ide
    • Organizer
      第49回日本生物物理学会
    • Place of Presentation
      兵庫県立大学(兵庫県)
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PUBLICLY-23113519
  • [Presentation] Mechanism for opening and closing by the KcsA channel2011

    • Author(s)
      M. Hirano, Y. Onishi, T. Yanagida, T. Ide
    • Organizer
      第49回 日本生物物理学会
    • Place of Presentation
      兵庫
    • Year and Date
      2011-09-18
    • Data Source
      KAKENHI-PROJECT-23770190
  • 1.  井出 徹
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 8 results

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