YAMAZAKI DAISUKE 山崎大介

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YAMAZAKI Daisuki 山崎大介

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Researcher Number	80588377
Other IDs
Affiliation (Current)	2025: 国立研究開発法人理化学研究所, 開拓研究所, 研究員
Affiliation (based on the past Project Information) *help	2023: 公益財団法人東京都医学総合研究所, 脳・神経科学研究分野, 研究員 2019 – 2022: 東京大学, 定量生命科学研究所, 講師 2017 – 2018: 東京大学, 定量生命科学研究所, 助教 2010 – 2017: 東京大学, 分子細胞生物学研究所, 助教
Review Section/Research Field	Principal Investigator Neuroscience in general / Basic Section 46010:Neuroscience-general-related / Neurophysiology / General neuroscience Except Principal Investigator Basic Section 45010:Genetics-related / Biological Sciences
Keywords	Principal Investigator ショウジョウバエ / CREB / 記憶学習 / キノコ体 / 記憶 / コトランスミッター / 忘却 / GABA / グルタミン酸 / ドーパミン … More / in vivo イメージング / オプトジェネティクス / 回路 / 記憶・学習 / プロテオミクス … More Except Principal Investigator 匂い記憶 / 記憶 / ドーパミン作動性神経 / 忘却 / ドーパミン / キノコ体 / ショウジョウバエ / 神経回路 / 情動 / Glu / KCs / 記憶形成 / キノコ体神経細胞 / 脆弱X症候群 / GABA作動性神経 / グルタミン酸作動性神経 / 連合記憶 / adenyryl cyclase / ライブイメージング / ドーパミン神経 / Ca2+ / 連合学習 / cAMP / 同時検出器 / アデニル酸シクラーぜ / GABA / グルタミン酸 / 記憶の素過程 / 記憶痕跡 / オスフェロモン / 求愛抑制効果 / DANs / MBON-γ1pedc / CREB / Caイメージング / CRE-n / CRE-p / キノコ体KCs / 扁桃体 / 相互抑制 / 罰記憶 / 報酬記憶 Less

Analysis of learning and forgetting mechanisms based on Dopamine and Co-transmittersPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Daisuke
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 46010:Neuroscience-general-related
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
  The University of Tokyo
Behavioral genetics of the neuronal system required for memory acquisition, consolidation and retrieval
- Principal Investigator
  
  Tabata Tetsuya
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45010:Genetics-related
- Research Institution
  The University of Tokyo
Revealing the mechanisms of memory formation, consolidation, and retrieval through CREB activity patternPrincipal Investigator
- Principal Investigator
  
  Yamazaki Daisuke
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurophysiology / General neuroscience
- Research Institution
  The University of Tokyo
Drosophila olfactory coding and memory
- Principal Investigator
  
  Tabata Tetsuya
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
Identification and functional analyses of memory-encoded cells in DrosophilaPrincipal Investigator
- Principal Investigator
  
  YAMAZAKI Daisuke
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neuroscience in general
- Research Institution
  The University of Tokyo
Functional proteomic analysis to identify memory formation-related proteins in the Drosophila mushroom bodies.Principal Investigator
- Principal Investigator
  
  YAMAZAKI Daisuki
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neuroscience in general
- Research Institution
  The University of Tokyo

All 2021 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 Other

All Journal Article Presentation

[Journal Article] Two Parallel Pathways Assign Opposing Odor Valences during Drosophila Memory Formation2018
- Author(s)
  Yamazaki Daisuke、Hiroi Makoto、Abe Takashi、Shimizu Kazumichi、Minami-Ohtsubo Maki、Maeyama Yuko、Horiuchi Junjiro、Tabata Tetsuya
- Journal Title
  
  Cell Reports
  
  Volume: 22 Issue: 9 Pages: 2346-2358
- DOI
  10.1016/j.celrep.2018.02.012
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06699, KAKENHI-PROJECT-15K06729, KAKENHI-PROJECT-18K06328, KAKENHI-PROJECT-18K06496, KAKENHI-PROJECT-17K17681, KAKENHI-PLANNED-25115008
[Journal Article] DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons.2017
- Author(s)
  Nitta Y, Yamazaki D, Sugie A, Hiroi M, Tabata T
- Journal Title
  
  Developmental Biology
  
  Volume: Jan15, 421 Issue: 2 Pages: 233-244
- DOI
  10.1016/j.ydbio.2016.11.015
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06699, KAKENHI-PLANNED-25115008
[Journal Article] Glial dysfunction causes age-related memory impairment in Drosophila.2014
- Author(s)
  Yamazaki D, Horiuchi J, Ueno K, Ueno T, Saeki S, Matsuno M, Naganos S, Miyashita T, Hirano Y, Nishikawa H, Taoka M, Yamauchi Y, Isobe T, Honda Y, Kodama T, Masuda T, Saitoe M
- Journal Title
  
  Neuron
  
  Volume: 84 Issue: 4 Pages: 753-763
- DOI
  10.1016/j.neuron.2014.09.039
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-13J08393, KAKENHI-ORGANIZER-25115001, KAKENHI-PLANNED-25115006, KAKENHI-PROJECT-25250010, KAKENHI-PROJECT-25430030, KAKENHI-PROJECT-26430030, KAKENHI-PROJECT-26560458, KAKENHI-PROJECT-26702037, KAKENHI-PLANNED-25115008
[Journal Article] The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway2014
- Author(s)
  Abe, T., Yamazaki, D., Murakami, S., Hiroi, M., Nitta, Y., Maeyama, Y., and Tabata T.
- Journal Title
  
  Development
  
  Volume: 141 Issue: 24 Pages: 4716-4728
- DOI
  10.1242/dev.113308
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24370086, KAKENHI-PROJECT-24500376, KAKENHI-PROJECT-26840112, KAKENHI-PLANNED-25115008
[Journal Article] Acute Inhibition of PKA Activity at Old Ages Ameliorates Age-Related Memory Impairment in Drosophila2010
- Author(s)
  Daisuke Yamazaki, Junjiro Horiuchi, Tomoyuki Miyashita, Minoru Saitoe
- Journal Title
  
  Journal of Neuroscience
  
  Volume: 30(46) Pages: 15573-15577
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22800012
[Presentation] ショウジョウバエの嗅覚記憶形成時におけるcAMPの動態2021
- Author(s)
  Yamazaki D、Abe T、Maeyama T and Tabata T.
- Organizer
  第44回日本神経科学会大会
- Data Source
  KAKENHI-PROJECT-19H03268
[Presentation] ショウジョウバエの嗅覚記憶情報のデコーディング2019
- Author(s)
  山崎大介
- Organizer
  第42回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19H03268
[Presentation] ショウジョウバエの嗅覚記憶における価値情報のデコーディング2019
- Author(s)
  山崎大介
- Organizer
  NEURO2019（第42回日本神経科学大会）
- Data Source
  KAKENHI-PROJECT-19H03268
[Presentation] ショウジョウバエの嗅覚記憶形成における罰情報経路と報酬情報経路の協働性2018
- Author(s)
  山崎大介
- Organizer
  分子生物学会
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] pathways assign opposing odor valences during Drosophila memory formation2018
- Author(s)
  山崎大介
- Organizer
  平成29年度新学術領域班会議・ワークショップ
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] Two parallel pathways assign opposing odor valences during Drosophila memory formation2018
- Author(s)
  山崎大介
- Organizer
  新学術領域班会議
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] ショウジョウバエの嗅覚記憶形成における罰情報経路と報酬情報経路の協働性2018
- Author(s)
  山崎大介、廣井誠、阿部崇志、清水一道、多羽田哲也
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] Two parallel pathways assinging opposite odor valences in Drosophila olfactory memory2017
- Author(s)
  Yamazaki, D., Hiroi, M., Abe, T., Maeyama, Y., Ohtsubo-Minami, M. and Tabata, T
- Organizer
  Structure and Function of the Insect Mushroom Body
- Place of Presentation
  Virginia (USA)
- Year and Date
  2017-03-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] Olfactory valence in Drosophila2017
- Author(s)
  山崎大介
- Organizer
  第10回分子高次機能研究会
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] Two parallel pathways assinging opposite odor valences in Drosophila olfactory memory.2017
- Author(s)
  Daisuke Yamazaki, Makoto Hiroi, Takashi Abe, Yuko Maeyama, Maki M Ohtsubo, Tetsuya Tabata
- Organizer
  Structure and Function of the Insect Mushroom Body
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] ショウジョウバエ嗅覚連合記憶における価値情報の維持機構2017
- Author(s)
  山崎大介
- Organizer
  第40回日本分子生物学会年会／2017年度生命科学系学会合同年次大会（ConBio2017）
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] Olfactory valence in Drosophila2017
- Author(s)
  山崎大介
- Organizer
  第10回分子高次機能研究会
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] ショウジョウバエ嗅覚連合記憶における価値情報の維持機構2017
- Author(s)
  山崎大介
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] Bidirectional switch of disihibition for differentiating positive and negative associations2016
- Author(s)
  Daisuke Yamazaki
- Organizer
  日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-07-20
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] Bidirectional switch of disihibition for di erentiating positive and negative associations.2016
- Author(s)
  Daisuke Yamazaki, Makoto Hiroi, Maki M Ohtsubo, Yuko Maeyama, Tetsuya Tabata
- Organizer
  第39回日本神経科学大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] A bidirectional neuronal switch assigning the odor valences2016
- Author(s)
  Daisuke Yamazaki, Makoto Hiroi, Maki Minami-Ohtsubo, Yuko Maeyama, Tetsuya Tabata
- Organizer
  新学術領域記憶ダイナミズム領域班会議
- Place of Presentation
  ヤマハリゾートつま恋（静岡県掛川市）
- Year and Date
  2016-06-27
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] CREBレポーター陽性・陰性細胞の記憶における役割2015
- Author(s)
  山崎大介
- Organizer
  第38回日本神経科学会大会
- Place of Presentation
  神戸国際展示場（兵庫県・神戸市）
- Year and Date
  2015-07-28
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] 報酬記憶と罰記憶を切り替える双方向性の脱抑制スイッチ回路2015
- Author(s)
  山崎大介
- Organizer
  包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  一橋講堂学術センター（東京都・千代田区）
- Year and Date
  2015-12-17
- Invited
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] 報酬記憶と罰記憶を切り替える双方向性脱抑制スイッチ2015
- Author(s)
  山崎大介
- Organizer
  第8回分子高次機能研究会
- Place of Presentation
  KKRホテル金沢（石川県・金沢市）
- Year and Date
  2015-08-17
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] 記憶形成による匂い情報への価値変化を規定する双方向回路の同定2015
- Author(s)
  山崎大介
- Organizer
  包括脳ネットワーク冬のシンポジウム
- Place of Presentation
  一橋講堂学術センター（東京都千代田区)
- Year and Date
  2015-12-17
- Invited
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] Bidirectional switch determining positive and negative associations in Drosophila olfactory memory2015
- Author(s)
  山崎大介
- Organizer
  新学術領域「多様性から明らかにする記憶ダイナミズムの共通原理」班会議
- Place of Presentation
  京都ガーデンパレス（京都府・京都市）
- Year and Date
  2015-11-04
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] 報酬記憶と罰記憶を切り替える双方向性脱抑制スイッチ2015
- Author(s)
  山崎大介
- Organizer
  第８回分子高次機能研究会
- Place of Presentation
  KKRホテル金沢（石川県金沢市）
- Year and Date
  2015-11-17
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] 記憶形成による匂い情報への価値変化を規定する双方向回路の同定2015
- Author(s)
  山崎大介
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway.2015
- Author(s)
  阿部崇志、山崎大介、村上智史、廣井誠、新田陽平、前山有子、多羽田哲也
- Organizer
  2015 Annual Drosophila Research Conference.
- Place of Presentation
  シカゴ（アメリカ）
- Year and Date
  2015-03-04
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] CREBレポーター陽性・陰性細胞の記憶における役割2015
- Author(s)
  山崎大介
- Organizer
  第38回日本神経科学会大会
- Place of Presentation
  神戸国際展示場（兵庫県神戸市）
- Year and Date
  2015-07-28
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] 記憶形成による匂い情報への価値変化を規定する双方向回路の同定2015
- Author(s)
  山崎大介
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸国際展示場（兵庫県・神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K06699
[Presentation] Sickie, a human MAP Nav2 homolog, facilitates F-actin-mediated axonal growth in Drosophila MB neurons by relaying non-canonical Rac signaling to the Cofilin pathway.2014
- Author(s)
  阿部崇志、山崎大介、村上智史、廣井誠、新田陽平、前山有子、多羽田哲也
- Organizer
  第11回日本ショウジョウバエ研究会
- Place of Presentation
  金沢歌劇座（石川県金沢市）
- Year and Date
  2014-06-04
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] CREBレポーターを用いたショウジョウバエ嗅覚記憶に関わる神経の解析2014
- Author(s)
  上岡雄太郎、山崎大介、市之瀬敏晴、大坪真樹、廣井誠、多羽田哲也
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2014-09-11
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] Genetic dissection of the mushroom bodies by CREB reporter flies that causes unique phenotypes in aversive olfactory memory.2014
- Author(s)
  Daisuke Yamazaki, Makoto Hiroi, Maki Ohtsubo-minami, Tetsuya Tabata.
- Organizer
  79th CSHL Symposium
- Place of Presentation
  Cold Spring Harbor Laboratory（アメリカ）
- Year and Date
  2014-05-30
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] Functional analyses of CREB reporter-positive mushroom body neurons in middle- and long-term memory in Drosophila.2013
- Author(s)
  Daisuke Yamazaki
- Organizer
  第36回日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県)
- Data Source
  KAKENHI-PLANNED-25115008
[Presentation] Functional analyses of CREB reporter-positive mushroom body neurons in middle- and long-term memory in Drosophila.2013
- Author(s)
  山崎大介
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24700310
[Presentation] Functional analyses of CREB-reporter-positive mushroom body neurons2013
- Author(s)
  山崎大介、廣井誠、市之瀬敏晴、大坪-南真樹、多羽田哲也
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2013-12-04
- Data Source
  KAKENHI-PROJECT-24700310
[Presentation] Memory traces in Droosphila revealed by CREB-dependent reporter gene expression2012
- Author(s)
  山崎大介、多羽田哲也
- Organizer
  日本神経科学会大会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-19
- Data Source
  KAKENHI-PROJECT-24700310
[Presentation] Long-term memory formation-dependent changes of CREB reporter signals in Drosophila2011
- Author(s)
  Daisuke Yamazaki, Makoto Hiroi, Toshiharu Ichinose, Tetsuya Tabata
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2011-12-13
- Data Source
  KAKENHI-PROJECT-22800012
[Presentation] Memory traces in Drosophila revealed by CREB-dependent reporter gene expression
- Author(s)
  山崎大介
- Organizer
  日本神経科学大会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-24700310

1. Tabata Tetsuya (10183865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. 廣井誠 (80597831)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
3. 阿部崇志 (70756824)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
4. 江島亜樹 (00548571)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 村上智史 (10463902)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 清水一道 (50808095)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMAZAKI DAISUKE 山崎 大介

YAMAZAKI Daisuki 山崎 大介

Research Projects

Research Products

Co-Researchers

Analysis of learning and forgetting mechanisms based on Dopamine and Co-transmittersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Behavioral genetics of the neuronal system required for memory acquisition, consolidation and retrieval

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Revealing the mechanisms of memory formation, consolidation, and retrieval through CREB activity patternPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Drosophila olfactory coding and memory

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and functional analyses of memory-encoded cells in DrosophilaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional proteomic analysis to identify memory formation-related proteins in the Drosophila mushroom bodies.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Two Parallel Pathways Assign Opposing Odor Valences during Drosophila Memory Formation2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] DISCO Interacting Protein 2 regulates axonal bifurcation and guidance of Drosophila mushroom body neurons.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Glial dysfunction causes age-related memory impairment in Drosophila.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The NAV2 homolog Sickie regulates F-actin-mediated axonal growth in Drosophila mushroom body neurons via the non-canonical Rac-Cofilin pathway2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Acute Inhibition of PKA Activity at Old Ages Ameliorates Age-Related Memory Impairment in Drosophila2010

Author(s)

Journal Title

Data Source

[Presentation] ショウジョウバエの嗅覚記憶形成時におけるcAMPの動態2021

Author(s)

Organizer

Data Source

[Presentation] ショウジョウバエの嗅覚記憶情報のデコーディング2019

Author(s)

Organizer

Data Source

[Presentation] ショウジョウバエの嗅覚記憶における価値情報のデコーディング2019

Author(s)

Organizer

Data Source

[Presentation] ショウジョウバエの嗅覚記憶形成における罰情報経路と報酬情報経路の協働性2018

Author(s)

Organizer

YAMAZAKI DAISUKE 山崎大介

YAMAZAKI Daisuki 山崎大介