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Ikebe Emi  池辺 詠美

Researcher Number 80593813
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0285-0466
Affiliation (Current) 2025: 国立健康危機管理研究機構, 国立感染症研究所 次世代生物学的製剤研究センター, 主任研究員
2025: 大分大学, 医学部, 客員研究員
Affiliation (based on the past Project Information) *help 2021 – 2023: 国立感染症研究所, 次世代生物学的製剤研究センター, 主任研究官
2020: 国立感染症研究所, 血液・安全性研究部, 主任研究官
Review Section/Research Field
Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
ATL / HTLV-1 / NAE阻害剤 / NAE 阻害剤 / 成人T細胞白血病 / 小胞体ストレス応答 / 小胞体ストレス
  • Research Projects

    (2 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (5 People)
  •  Neddylation pathwayを標的とした新規ATL治療薬の開発Principal Investigator

    • Principal Investigator
      池辺 詠美
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      National Institute of Infectious Diseases
  •  Development of prophylactic agents for ATL development by targeting ER stress inductionPrincipal Investigator

    • Principal Investigator
      Ikebe Emi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      National Institute of Infectious Diseases

All 2024 2023 2022 2021 2020

All Journal Article Presentation Patent

  • [Journal Article] IMiD/CELMoD-induced growth suppression of adult T-cell leukemia/lymphoma cells via cereblon through downregulation of target proteins and their downstream effectors2024

    • Author(s)
      Wang Yu、Shimosaki Shunsuke、Ikebe Emi、Iha Hidekatsu、Yamamoto Jun-ichi、Fife Nichole、Ichikawa Tomonaga、Hori Mitsuo、Ogata Masao、Tsukamoto Yoshiyuki、Hijiya Naoki、Moriyama Masatsugu、Hagiwara Shotaro、Kusano Shuichi、Saito Masumichi、Ahmed Kamruddin、Nishizono Akira、Handa Hiroshi、Morishita Kazuhiro
    • Journal Title

      Frontiers in Oncology

      Volume: 13 Pages: 01-13

    • DOI

      10.3389/fonc.2023.1272528

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K15312, KAKENHI-PROJECT-23K07943, KAKENHI-PROJECT-21K07128
  • [Journal Article] Proteomic analysis of adult T-cell leukemia/lymphoma: A biomarker identification strategy based on preparation and in-solution digestion methods of total proteins2024

    • Author(s)
      Sudo Haruka、Tonoyama Yasuhiro、Ikebe Emi、Hasegawa Hiroo、Iha Hidekatsu、Ishida Yo-ichi
    • Journal Title

      Leukemia Research

      Volume: 138 Pages: 107454-107454

    • DOI

      10.1016/j.leukres.2024.107454

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K15312
  • [Journal Article] Performance evaluation of Espline HTLV-I/II, a newly developed rapid immunochromatographic antibody test for different diagnostic situations2023

    • Author(s)
      Kuramitsu M, Momose H, Uchida Y, Ishitsuka K, Kubota R, Tokunaga M, Utsunomiya A, Umekita K, Hashikura Y, Nosaka K, Koh K-R, Nakamura H, Sagara Y, Sobata R, Satake M, Nagata K, Hasegawa Y, Sasaki D, Hasegawa H, Sato T, Yamano Y, Hiraga K, Tezuka K, Ikebe E, Matsuoka S, Okuma K, Watanabe T, Miura K, Hamaguchi I.
    • Journal Title

      Microbiology Spectrum

      Volume: 11 Issue: 6 Pages: 1-10

    • DOI

      10.1128/spectrum.02078-23

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K15312, KAKENHI-PROJECT-21K09497, KAKENHI-PROJECT-22K08594, KAKENHI-PROJECT-22K09622, KAKENHI-PROJECT-23K06954, KAKENHI-PROJECT-23K24233, KAKENHI-PROJECT-23K24248, KAKENHI-PROJECT-23K24380
  • [Journal Article] TAS‐116 (pimitespib), a heat shock protein 90 inhibitor, shows efficacy in preclinical models of adult T‐cell leukemia2021

    • Author(s)
      Ikebe Emi、Shimosaki Shunsuke、Hasegawa Hiroo、Iha Hidekatsu、Tsukamoto Yoshiyuki、Wang Yu、Sasaki Daisuke、Imaizumi Yoshitaka、Miyazaki Yasushi、Yanagihara Katsunori、Hamaguchi Isao、Morishita Kazuhiro
    • Journal Title

      Cancer Science

      Volume: 113 Issue: 2 Pages: 684-696

    • DOI

      10.1111/cas.15204

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18H02733, KAKENHI-PROJECT-20K17390, KAKENHI-PROJECT-23K21375
  • [Journal Article] Activation of PERK-ATF4-CHOP pathway as a novel therapeutic approach for efficient elimination of HTLV-1-infected cells2020

    • Author(s)
      Ikebe E, Matsuoka S, Tezuka K, Kuramitsu M, Okuma K, Nakashima M,, Seiichiro Kobayashi S, Makiyama J, Yamagishi M, Oyadomari S, Uchimaru K, Hamaguchi I
    • Journal Title

      Blood adv

      Volume: 4 Issue: 9 Pages: 1845-1858

    • DOI

      10.1182/bloodadvances.2019001139

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08378, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-20K07670, KAKENHI-PROJECT-19K16032, KAKENHI-PROJECT-20K17390, KAKENHI-PROJECT-19H02853, KAKENHI-PROJECT-19H03575, KAKENHI-PROJECT-19K16580
  • [Patent] 成人T細胞白血病の予防及び/又は治療剤2020

    • Inventor(s)
      浜口功、松岡佐保子、池辺詠美、親泊政一
    • Industrial Property Rights Holder
      浜口功、松岡佐保子、池辺詠美、親泊政一
    • Industrial Property Rights Type
      特許
    • Filing Date
      2020
    • Data Source
      KAKENHI-PROJECT-20K17390
  • [Presentation] NAE阻害剤の新規ATL治療薬としての有用性の検討2023

    • Author(s)
      池辺 詠美, 松岡 佐保子, 中島 誠, 村岡 弘美, 吉村 千穂子, 山岸 誠, 内丸 薫, 伊波 英克, 浜口 功.
    • Organizer
      第9回日本HTLV-1学会学術集会
    • Data Source
      KAKENHI-PROJECT-23K15312
  • [Presentation] 成人T細胞白血病・リンパ腫(ATL)治療薬としてのNEDD8活性化酵素(NAE)阻害剤の有効性の検討2023

    • Author(s)
      池辺詠美
    • Organizer
      文部科学省科学研究費助成事業 学術変革領域研究【学術研究支援基盤形成】令和4年度コホート・生体試料支援プラットフォーム 若手支援研究成果発表会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K15312
  • [Presentation] 成人T細胞白血病・リンパ腫(ATL)治療薬としてのNEDD8活性化酵素(NAE)阻害剤の有効性の検討2023

    • Author(s)
      池辺 詠美
    • Organizer
      令和4年度コホート・生体試料支援プラットフォーム 若手支援研究成果発表会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K17390
  • [Presentation] オンラインシステムにて収集した輸血副反応動向 ―15年間のまとめと今後の取り組み―2022

    • Author(s)
      池辺詠美
    • Organizer
      第70回日本輸血・細胞治療学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K17390
  • [Presentation] HTLV-1関連疾患に対するNEDD8活性化酵素阻害剤の有効性の検討2022

    • Author(s)
      池辺 詠美、松岡 佐保子、中島 誠、村岡 弘美、吉村 千穂子、山岸 誠、内丸 薫、伊波 英克、浜口 功
    • Organizer
      第8回日本HTLV学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K17390
  • [Presentation] NEDD8活性化酵素はHTLV-1関連疾患の新規治療標的である2022

    • Author(s)
      池辺 詠美、松岡 佐保子、中島 誠、村岡 弘美、吉村 千穂子、山岸 誠、内丸 薫、伊波 英克、浜口 功
    • Organizer
      第84回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-20K17390
  • [Presentation] 小胞体ストレス応答を標的とした新規抗HTLV-1薬の開発2020

    • Author(s)
      池辺 詠美、松岡 佐保子、手塚 健太、倉光 球、大隈 和、中島 誠、小林 誠一郎、牧山 純也、山岸 誠、親 泊 政一、内丸 薫、浜口 功
    • Organizer
      第93回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K17390
  • 1.  HASEGAWA Hiroo
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 2.  柳原 克紀
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 3.  今泉 芳孝
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  佐々木 大介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  浜口 功
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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