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Watanabe Shojiro  渡邊 祥二郎

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渡邊 祥二郎  ワタナベ ショウジロウ

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Researcher Number 80597196
Affiliation (Current) 2025: 愛媛大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help 2023: 愛媛大学, 医学系研究科, 講師
2022: 愛媛大学, 医学系研究科, 特任講師
2021: 愛媛大学, 医学系研究科, 助教
2019 – 2020: 弘前大学, 医学部附属病院, 助教
2016 – 2017: 弘前大学, 医学部附属病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Keywords
Principal Investigator
リツキシマブ / SMPDL3b / ネフローゼ症候群 / IL6 / Toll like receptor 3 / 自然免疫 / 細胞骨格 / 脂質ラフト / Raftlin / TLR3 … More / ポドサイト / 小児特発性ネフローゼ症候群 / 細胞、組織 / 蛍光抗体法 / 難治性ネフローゼ症候群 Less
  • Research Projects

    (2 results)
  • Research Products

    (19 results)
  • Co-Researchers

    (2 People)
  •  小児特発性ネフローゼ症候群におけるSMPDL-3bの意義の解明Principal Investigator

    • Principal Investigator
      渡邊 祥二郎
    • Project Period (FY)
      2019 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Ehime University
      Hirosaki University
  •  The B cell independent mechanism of Rituximab in Pediatric-Onset Intractable Nephrotic Syndrome.Principal Investigator

    • Principal Investigator
      Watanabe Shojiro
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Hirosaki University

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Sphingomyelin Phosphodiesterase Acid-Like 3b is Essential for Toll-Like Receptor 3 Signaling in Human Podocytes.2022

    • Author(s)
      1.Watanabe S, Umetsu H, Hashimoto S, Sato R, Aizawa T, Tsugawa K, Imaizumi T, Tanaka H
    • Journal Title

      The Journal of Membrane Biology

      Volume: 255 Issue: 1 Pages: 117-122

    • DOI

      10.1007/s00232-021-00206-w

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K08338, KAKENHI-PROJECT-22K07862
  • [Journal Article] Podocyte sphingomyelin phosphodiesterase acid-like 3b decreases among children with idiopathic nephrotic syndrome2021

    • Author(s)
      Shojiro Watanabe, Koji Hirono, Tomomi Aizawa, Koji Tsugawa, Kensuke Joh, Tadaatsu Imaizumi, Hiroshi Tanaka
    • Journal Title

      Clinical and Experimental Nephrology

      Volume: 25 Issue: 1 Pages: 44-51

    • DOI

      10.1007/s10157-020-01970-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Journal Article] Interleukin-6 via Toll-Like Receptor 3 Signaling Attenuates the Expression of Proinflammatory Chemokines in Human Podocytes2021

    • Author(s)
      Hidenori Umetsu, Shojiro Watanabe, Tadaatsu Imaizumi, Tomomi Aizawa, Koji Tsugawa, Shogo Kawaguchi, Kazuhiko Seya, Tomoh Matsumiya, Hiroshi Tanaka
    • Journal Title

      Kidney and Blood Pressure Research

      Volume: - Issue: 2 Pages: 207-218

    • DOI

      10.1159/000514589

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Journal Article] Urinary excretion of SMPDL-3b in children with intractable nephrotic syndrome.2017

    • Author(s)
      Watanabe S, Tsugawa K, Tsuruga K, Imaizumi T, Tanaka H
    • Journal Title

      Pediatrics International

      Volume: 59 Issue: 10 Pages: 1112-1115

    • DOI

      10.1111/ped.13355

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10055, KAKENHI-PROJECT-16K19623
  • [Presentation] Sphingomyelin phosphodiesterase acid-like 3b (SMPDL3b) mediates TLR3 signaling in human podocytes.2021

    • Author(s)
      Watanabe S, KarasawaT, Hashimoto S, Umetsu H, SatoR, FujitaM, Aizawa T, Tsugawa K, Tanaka H
    • Organizer
      The 18th Japan-Korea-China Pediatric Nephrology Seminar 2021.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] リツキシマブはpodocyteのTLR 3を起点とするIL-6発現を増強する2021

    • Author(s)
      渡邊 祥二郎
    • Organizer
      第55回日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] リツキシマブはpodocyteのToll-like receptor 3(TLR3)を起点とするIL-6発現を増強する2020

    • Author(s)
      渡邊 祥二郎
    • Organizer
      第62回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] Rituximab Enhances the Expression of Interleukin-6 via Toll-like receptor 3 signaling in Human Podocyte2020

    • Author(s)
      Shojiro Watanabe
    • Organizer
      57th ERA-EDTA Congress 2020
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] 小児特発性ネフローゼ症候群におけるSMPDL3b2020

    • Author(s)
      渡邊 祥二郎
    • Organizer
      第123回日本小児科学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] RITUXIMAB ENHANCES THE EXPRESSION OF INTERLEUKIN-6 VIA TOLL-LIKE RECEPTOR 3 SIGNALING IN HUMAN PODOCYTE2020

    • Author(s)
      Shojiro Watanabe
    • Organizer
      第57回欧州腎臓学会・欧州透析移植学会
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] 小児特発性ネフローゼ症候群におけるSMPDL3b2020

    • Author(s)
      渡邊 祥二郎
    • Organizer
      第123回日本小児科学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] リツキシマブはpodocyteのToll-like receptor 3を起点とするIL-6発現を増強する2020

    • Author(s)
      渡邊 祥二郎
    • Organizer
      第63回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] リツキシマブはpodocyteのTLR 3を起点とするIL-6発現を増強する2020

    • Author(s)
      渡邊 祥二郎
    • Organizer
      第55回日本小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] Implication of Urinary SMPDL3b Expression in children with Idiopathic Nephrotic Syndrome2019

    • Author(s)
      Shojiro Watanabe
    • Organizer
      18th Congress of the International Pediatric Nephrology Association
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K08338
  • [Presentation] URINARY EXCRETION AND GLOMERULAR EXPRESSION OF SPHINGOMYELINASE PHOSPHODIESTERASE ACID-LIKE 3B IN PEDIATRIC-ONSET NEPHROTIC SYNDROME2018

    • Author(s)
      Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Kazushi Tsuruga, Etsuro Ito, Hiroshi Tanaka
    • Organizer
      the 55th ERA-EDTA Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19623
  • [Presentation] 特発性ネフローゼ症候群における糸球体上皮細胞のSphingomyelin-phosphodiesterase acid-like 3b (SMPDL-3b)2018

    • Author(s)
      渡邊 祥二郎、田中 完
    • Organizer
      第53回小児腎臓病学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K19623
  • [Presentation] Urinary and glomerular expressions of SMPDL3b in pediatric-onset intractable nephrotic syndrome2017

    • Author(s)
      Shojiro Watanabe, Tomomi Aizawa, Koji Tsugawa, Kazushi Tsuruga, Hiroshi Tanaka
    • Organizer
      13th Asian Congress of Pediatric Nephrology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19623
  • [Presentation] 小児難治性ネフローゼ症候群でのSphingomyelin Phosphodiesterase Acid Like 3B (SMPDL3b)の発現に関する検討2017

    • Author(s)
      渡邊 祥二郎、津川 浩二、敦賀 和志、田中 完
    • Organizer
      第60回日本腎臓学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K19623
  • [Presentation] Urinary and glomerular expressions of SMPDL3b in pediatric onset intractable nephrotic syndrome2017

    • Author(s)
      Shojiro Watanabe, Kouji Tsugawa, Kazushi Tsuruga, Hiroshi Tanaka
    • Organizer
      第52回小児腎臓病学会学術集会
    • Data Source
      KAKENHI-PROJECT-16K19623
  • 1.  田中 完 (50271820)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 2.  今泉 忠淳 (90232602)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results

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