Arime Yosefu 有銘預世布

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ARIME Yosefu 有銘預世布

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Researcher Number	80609404
Other IDs
Affiliation (Current)	2025: 獨協医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2017 – 2023: 獨協医科大学, 医学部, 講師 2014 – 2016: 獨協医科大学, 医学部, 助教 2011 – 2012: 獨協医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Psychiatric science / Basic Section 52030:Psychiatry-related
Keywords	Principal Investigator 動物モデル / 統合失調症 / 認知機能障害 / 神経回路 / ワーキングメモリー / 抗精神病薬 / モデルマウス / パルブアルブミン陽性抑制性神経細胞 / 前頭前野 / 前辺縁皮質 … More / 行動 / 認知機能 / ワーキングメモリ / in vivoイメージング / 化学遺伝学 / パルブアルブミン陽性抑制性神経 / 神経科学 / 精神疾患 / in vivo カルシウムイメージング / In vivoカルシウムイメージング / 背内側線条体 / プロテオミクス / 受容体占有率 / 行動薬理 / 神経精神薬理 / 行動試験 / 定量プロテオミクス / 受容体占拠率 Less

臨床への適用を見据えたワーキングメモリ障害改善薬の創出Principal Investigator
- Principal Investigator
  
  有銘預世布
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Dokkyo Medical University
Exploration for therapeutic strategy to improve working memory deficit in an animal model of schizophrenia under clinically relevant antipsychotic dose regimenPrincipal Investigator
- Principal Investigator
  
  Arime Yosefu
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52030:Psychiatry-related
- Research Institution
  Dokkyo Medical University
Identification of neural circuits underlying working memory impairmentsPrincipal Investigator
- Principal Investigator
  
  Arime Yosefu
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Dokkyo Medical University
Exploration of novel targets for treating schizophreniaPrincipal Investigator
- Principal Investigator
  
  Arime Yosefu
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Psychiatric science
- Research Institution
  Dokkyo Medical University
Analysis of the mechanism of action of antipsychotics by highly sensitive quantitative proteomicsPrincipal Investigator
- Principal Investigator
  
  ARIME Yosefu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Psychiatric science
- Research Institution
  Dokkyo Medical University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2023
- Author(s)
  Arime Yosefu、Saitoh Yoshito、Ishikawa Mikiko、Kamiyoshihara Chikako、Uchida Yasuo、Fujii Kazuki、Takao Keizo、Akiyama Kazufumi、Ohkawa Noriaki
- Journal Title
  
  Neuropsychopharmacology
  
  Volume: 49 Issue: 4 Pages: 720-730
- DOI
  10.1038/s41386-023-01769-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K17422, KAKENHI-PROJECT-23K07042, KAKENHI-PROJECT-20K07925, KAKENHI-PROJECT-21K15006, KAKENHI-PROJECT-19H03538
[Journal Article] Activation of prefrontal parvalbumin interneurons ameliorates treatment-resistant working memory deficit even under continuous antipsychotic treatment in a mouse model of schizophrenia2023
- Author(s)
  Arime Yosefu、Saitoh Yoshito、Ishikawa Mikiko、Kamiyoshihara Chikako、Uchida Yasuo、Fujii Kazuki、Takao Keizo、Akiyama Kazufumi、Ohkawa Noriaki
- Journal Title
  
  bioRxiv
  
  Volume: Posted March 01 Pages: 1-77
- DOI
  10.1101/2023.02.27.530344
- Open Access
- Data Source
  KAKENHI-PROJECT-20K07925
[Journal Article] 統合失調症におけるトランスレーショナルリサーチの現状と今後の展開2020
- Author(s)
  有銘　預世布
- Journal Title
  
  Dokkyo Journal of Medical Sciences
  
  Volume: 47 Pages: 175-182
- NAID
  120006951348
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07925
[Journal Article] Abnormal neural activation patterns underlying working memory impairment in chronic phencyclidine-treated mice2017
- Author(s)
  Arime Y, Akiyama K
- Journal Title
  
  PLOS ONE
  
  Volume: 12 Issue: 12 Pages: e0189287-e0189287
- DOI
  10.1371/journal.pone.0189287
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10192, KAKENHI-PROJECT-17K16397
[Journal Article] Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.2014
- Author(s)
  Arime Y, Fukumura R, Miura I, Mekada K, Yoshiki A, Wakana S, Gondo Y, Akiyama K.
- Journal Title
  
  Behavioral and Brain Functions
  
  Volume: 10 Issue: 1 Pages: 1-13
- DOI
  10.1186/1744-9081-10-45
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25241016, KAKENHI-PROJECT-26250024, KAKENHI-PROJECT-26860942
[Presentation] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2024
- Author(s)
  Arime Y, Saitoh Y, Ishikawa M, Kamiyoshihara C, Uchida Y, Fujii K, Takao K, Akiyama K, Ohkawa N
- Organizer
  The International College of Neuropsychopharmacology (CINP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07042
[Presentation] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2024
- Author(s)
  Arime Y, Saitoh Y, Ishikawa M, Kamiyoshihara C, Uchida Y, Fujii K, Takao K, Akiyama K, Ohkawa N.
- Organizer
  The International College of Neuropsychopharmacology (CINP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] 統合失調症モデルにおける認知機能障害の改善　ー臨床への適用を目指してー2024
- Author(s)
  有銘預世布
- Organizer
  第7回包括的神経グリア研究会（UNG2024）
- Data Source
  KAKENHI-PROJECT-23K07042
[Presentation] 不随意運動を認める症例シリーズ－精神科臨床で成人型ニーマンピック病C型の可能性を考える－2023
- Author(s)
  藤井久彌子, 前川正充, 齋藤尚大, 篠﨑將貴, 有銘預世布, 岡安寛明, 下田和孝, 尾関祐二．
- Organizer
  精神科診断学会
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] 不随意運動を認める症例シリーズ－精神科臨床で成人型ニーマンピック病C型の可能性を考える－2023
- Author(s)
  藤井久彌子, 前川正充, 齋藤尚大, 篠﨑將貴, 有銘預世布, 岡安寛明, 下田和孝, 尾関祐二
- Organizer
  第42回精神科診断学会
- Data Source
  KAKENHI-PROJECT-23K07042
[Presentation] 統合失調症マウスモデルにおける臨床を反映した抗精神病薬投与下での認知機能障害の新規治療戦略2022
- Author(s)
  有銘預世布、斎藤喜人、内田康雄、石河三貴子、上吉原千賀子、藤井一希、高雄啓三、大川宜昭
- Organizer
  第45回日本神経科学大会・第65回日本神経化学会大会・第32回日本神経回路学会大会
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] パルブアルブミン陽性抑制性細胞の活動制御は臨床を反映した抗精神病薬慢性投与下でも認知機能障害を改善させる2022
- Author(s)
  有銘預世布、斎藤喜人、内田康雄、石河三貴子、上吉原千賀子、藤井一希、高雄啓三、大川宜昭
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] 診断が統合失調症である症例で成人型ニーマンピック病C型の可能性を検討する2022
- Author(s)
  藤井久彌子, 前川正充, 齋藤尚大, 篠﨑將貴, 有銘預世布, 岡安寛明, 下田和孝, 尾関祐二
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] A novel therapeutic strategy for cognitive dysfunctions under clinically relevant antipsychotic treatment in a mouse model of schizophrenia2022
- Author(s)
  Arime Y
- Organizer
  Learning & Memory Meeting 2022
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] 『薬剤性』と判断される統合失調症のジストニアについて成人型ニーマンピック病C型の可能性を検討する2021
- Author(s)
  藤井久彌子, 前川正充, 衞藤義勝, 齋藤尚大, 篠﨑將貴, 有銘預世布, 永島隆秀, 岡安寛明, 下田和孝, 尾関祐二
- Organizer
  第43回日本生物学的精神医学会・第51回日本神経精神薬理学会　合同年会
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] フェンサイクリジン慢性投与マウスが示すワーキングメモリー障害は化学遺伝学的手法と臨床用量を反映した抗精神病薬慢性投与の併用によって改善される2021
- Author(s)
  有銘預世布, 斎藤喜人, 内田康雄, 石河三貴子, 上吉原千賀子, 藤井一希, 高雄啓三, 大川宜昭
- Organizer
  第44回日本神経科学大会・第1回CJK国際会議
- Data Source
  KAKENHI-PROJECT-20K07925
[Presentation] Examination of the findings suggesting Niemann-Pick disease type C in patients with schizophrenia.2019
- Author(s)
  Fujii K, Maekawa M, Ozeki Y, Eto Y, Saito T, Shinozaki M, Arime Y, Nagashima T, Okayasu H, Ishii S, Shimoda K
- Organizer
  International Congress on Schizophrenia Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16397
[Presentation] Abnormal neural activation patterns underlying working memory impairment in chronic phencyclidine-treated mice.2018
- Author(s)
  Arime Y, Akiyama K
- Organizer
  The Society for Neuroscience (SfN) 48th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16397
[Presentation] Phencyclidine慢性投与マウスが示すワーキングメモリー障害の神経基盤の探索2018
- Author(s)
  有銘預世布，秋山一文
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会　合同年会
- Data Source
  KAKENHI-PROJECT-17K16397
[Presentation] 統合失調症と診断された症例を対象とした成人型ニーマンピック病C型を示唆する所見の検討2018
- Author(s)
  藤井久彌子，前川正充，衞藤義勝，尾関祐二，齋藤尚大，有銘預世布，永島隆秀，岡安寛明，篠﨑隆央，秋山一文，下田和孝
- Organizer
  第40回日本生物学的精神医学会・第61回日本神経化学会大会　合同年会
- Data Source
  KAKENHI-PROJECT-17K16397
[Presentation] Investigation of anatomical basis underlying working memory impairment in chronic phencyclidine-treated mice2016
- Author(s)
  Yosefu Arime, Kazufumi Akiyama
- Organizer
  The Society for Neuroscience (SfN) 46th Annual Meeting
- Place of Presentation
  San Diego Convention Center, CA, USA
- Year and Date
  2016-11-12
- Data Source
  KAKENHI-PROJECT-26860942
[Presentation] 統合失調症のワーキングメモリー障害に関わる神経回路基盤の探索2016
- Author(s)
  有銘預世布、秋山一文
- Organizer
  新学術領域　先端モデル動物支援プラットフォーム　若手支援技術講習会
- Place of Presentation
  蓼科グランドホテル滝の湯（長野県茅野市）
- Year and Date
  2016-09-14
- Data Source
  KAKENHI-PROJECT-26860942
[Presentation] 統合失調症のワーキングメモリー障害に関わる神経回路基盤の探索2016
- Author(s)
  有銘預世布、秋山一文
- Organizer
  第8回光操作研究会
- Place of Presentation
  慶應義塾大学（東京都港区）
- Year and Date
  2016-09-29
- Data Source
  KAKENHI-PROJECT-26860942
[Presentation] フェンサイクリジン慢性投与マウスが示すワーキングメモリー障害2014
- Author(s)
  有銘預世布，秋山一文
- Organizer
  第37回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2014-09-13
- Data Source
  KAKENHI-PROJECT-26860942
[Presentation] The effects of clinically relevant antipsychotics dose regimen on chronic phencyclidine treated mice2013
- Author(s)
  Arime Y, Akiyama K
- Organizer
  The Society for Neuroscience (SfN) 43rd Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23890200
[Presentation] The effects of clinically relevant antipsychotics dose regimen on chronic phencyclidine-treated mice2013
- Author(s)
  Arime Y, Akiyama K
- Organizer
  The Society for Neuroscience (SfN) 43rd Annual Meeting
- Place of Presentation
  San Diego, CA, USA
- Data Source
  KAKENHI-PROJECT-23890200
[Presentation] Comparison of behavioral characteristics between genetic and pharmacological animal models of schizophrenia.2012
- Author(s)
  Arime Y, Akiyama K
- Organizer
  The Society for Neuroscience (SfN) 42nd Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-23890200
[Presentation] Comparison of behavioral characteristics between genetic and pharmacological animal models of schizophrenia2012
- Author(s)
  Arime Y, Akiyama K
- Organizer
  The Society for Neuroscience (SfN) 42nd Annual Meeting
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-23890200
[Presentation] 統合失調症のワーキングメモリー障害に関わる神経回路基盤の探索
- Author(s)
  有銘預世布，秋山一文
- Organizer
  第4回東北脳科学ウィンタースクール
- Place of Presentation
  蔵王
- Year and Date
  2015-02-21 – 2015-02-22
- Data Source
  KAKENHI-PROJECT-26860942

1. TAKAO Keizo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 秋山一文

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 権藤洋一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Arime Yosefu 有銘 預世布

ARIME Yosefu 有銘 預世布

Research Projects

Research Products

Co-Researchers

臨床への適用を見据えたワーキングメモリ障害改善薬の創出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration for therapeutic strategy to improve working memory deficit in an animal model of schizophrenia under clinically relevant antipsychotic dose regimenPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of neural circuits underlying working memory impairmentsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Exploration of novel targets for treating schizophreniaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of the mechanism of action of antipsychotics by highly sensitive quantitative proteomicsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Activation of prefrontal parvalbumin interneurons ameliorates treatment-resistant working memory deficit even under continuous antipsychotic treatment in a mouse model of schizophrenia2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 統合失調症におけるトランスレーショナルリサーチの現状と今後の展開2020

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Abnormal neural activation patterns underlying working memory impairment in chronic phencyclidine-treated mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of background mutations and single nucleotide polymorphisms (SNPs) on the Disc1 L100P behavioral phenotype associated with schizophrenia in mice.2014

Author(s)

Journal Title

DOI

Data Source

[Presentation] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2024

Author(s)

Organizer

Data Source

[Presentation] Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia2024

Author(s)

Organizer

Data Source

[Presentation] 統合失調症モデルにおける認知機能障害の改善 ー臨床への適用を目指してー2024

Author(s)

Organizer

Data Source

[Presentation] 不随意運動を認める症例シリーズ－精神科臨床で成人型ニーマンピック病C型の可能性を考える－2023

Author(s)

Organizer

Data Source

[Presentation] 不随意運動を認める症例シリーズ－精神科臨床で成人型ニーマンピック病C型の可能性を考える－2023

Author(s)

Organizer

Data Source

Arime Yosefu 有銘預世布

ARIME Yosefu 有銘預世布

[Presentation] 統合失調症モデルにおける認知機能障害の改善　ー臨床への適用を目指してー2024