Ihara Eikichi 伊原栄吉

… Alternative Names

IHARA Eikichi 伊原栄吉

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Researcher Number	80612390
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2019 – 2023: 九州大学, 医学研究院, 准教授 2011 – 2019: 九州大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Gastroenterology / Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator 高解像度食道内圧検査 / 食道アカラシア / 機能性嚥下障害 / 拡張障害 / 食道拡張障害 / 食道運動機能障害 / アカラシアサブタイプ / 食道赤ラシア / 経口内視鏡的筋層切開術 / サイトカインプロフィール … More / Na+/Ca2+交換機転 / 細胞内カルシウム / 筋原性筋緊張調節性筋緊張調節 / 食道運動異常症 / 硫化水素 / 筋原性筋緊張調節 / 下部食道括約筋 / アカラシア / alpha-toxin / カルバコール / MLCP / MLCK / K^+脱分極刺激 / 腸管平滑筋 / カルシウム感受性 / 消化管免疫 / 消化管平滑筋 / Th17 / IL-17 / IL-23 … More Except Principal Investigator TGF-β / 炎症性腸疾患 / 多様性 / 抗自律神経節アセチルコリン受容体抗体 / 自律神経外障害 / 小児神経 / サルコイドーシス / 膠原病 / 能動免疫 / 自律神経節アセチルコリン受容体 / 自律神経障害 / 動物モデル / 自己抗体 / 自律神経節 / 自己免疫性自律神経節障害 / 細菌 / 免疫学 / 内科 / 酪酸 / 腸内細菌 / 制御性T細胞 / シグナル伝達 / サイトカイン / proinflammatory cytokine / TGF-beta / 炎症性サイトカイン / smad7 Less

Establishing disease concept of new type of esophageal motility dysfunction due to altered distention and elucidation of its pathogenesisPrincipal Investigator
- Principal Investigator
  
  伊原栄吉
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyushu University
Elucidation of esophageal achalasia based on their subtypes from the multiple perspectives.Principal Investigator
- Principal Investigator
  
  IHARA EIKICHI
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyushu University
Multidisciplinary analysis of heterogeneity in autoimmune autonomic ganglionopathy
- Principal Investigator
  
  Nakane Shunya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Nippon Medical School
  Kumamoto University
Determination of underlying cause of esophageal achalasia by the use of cytokine profilesPrincipal Investigator
- Principal Investigator
  
  Ihara Eikichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Induction of the cell surface-bound TGF-beta on the regulatory T cells by enteric bacteria and its fermentation product.
- Principal Investigator
  
  Nakamura Kazuhiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Investigation of myogenic tone regulation in lower esophageal sphincter to develop novel treatments for achalasiaPrincipal Investigator
- Principal Investigator
  
  Ihara Eikichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
The mechanism of increased smad7 expression in the intestinal mucosa of inflammatory bowel disease and the exploitation of a new therapy
- Principal Investigator
  
  Nakamura Kazuhiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University
Effects of IL-23 and Th17 on intestinal smooth muscle contractility and its underlying mechanismPrincipal Investigator
- Principal Investigator
  
  IHARA Eikichi
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Gastroenterology
- Research Institution
  Kyushu University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation

[Journal Article] The interplay between alterations in esophageal microbiota associated with th17 immune response and impaired LC20 phosphorylation in achalasia.2024
- Author(s)
  Ikeda H, Ihara E, Takeya K, Mukai K, Onimaru M, Ouchida K, Hata Y, Bai X, Tanaka Y, Sasaki T, Saito F, Eto M, Nakayama J, Oda Y, Nakamura M, Inoue H, Ogawa Y
- Journal Title
  
  J Gastroenterol
  
  Volume: In press Issue: 5 Pages: 361-375
- DOI
  10.1007/s00535-024-02088-w
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K07440, KAKENHI-PROJECT-22K19530
[Journal Article] Determination of Region-Specific Roles of the M3 Muscarinic Acetylcholine Receptor in Gastrointestinal Motility2022
- Author(s)
  Igarashi-Hisayoshi Yoko、Ihara Eikichi、Bai Xiaopeng、Higashi Chika、Ikeda Hiroko、Tanaka Yoshimasa、Hirano Mayumi、Ogino Haruei、Chinen Takatoshi、Taguchi Yasushi、Ogawa Yoshihiro
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 68 Issue: 2 Pages: 439-450
- DOI
  10.1007/s10620-022-07637-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19530, KAKENHI-PROJECT-20K08334
[Journal Article] Improved esophagography screening for esophageal motility disorders using wave appearance and supra-junctional ballooning2022
- Author(s)
  Hata Yoshitaka、Ihara Eikichi、Wada Masafumi、Tsuru Hirotaka、Muta Kazumasa、Minoda Yosuke、Bai Xiaopeng、Esaki Mitsuru、Tanaka Yoshimasa、Chinen Takatoshi、Ogino Haruei、Sakamoto Ryuichi、Ogawa Yoshihiro
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 57 Issue: 11 Pages: 838-847
- DOI
  10.1007/s00535-022-01913-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19530, KAKENHI-PROJECT-20K08334
[Journal Article] A novel murine model of autoimmune dysautonomia by α3 nicotinic acetylcholine receptor immunization2022
- Author(s)
  Yamakawa M, Nakane S, Ihara E, Tawara N, Ikeda H, Igarashi Y, Komohara Y, Takamatsu K, Ikeda T, Tomita Y, Murai S, Ando Y, Mukaino A, Ogawa Y, Ueda M.
- Journal Title
  
  Front Neurosci
  
  Volume: 16 Pages: 1006923-1006923
- DOI
  10.3389/fnins.2022.1006923
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07528, KAKENHI-PROJECT-19K17012, KAKENHI-PROJECT-19H03549
[Journal Article] The treatment effects of acotiamide in esophagogastric outflow obstruction: A prospective longitudinal observational study.2022
- Author(s)
  Ihara E, Ogino H, Muta K, Hamada S, Wada M, Hata Y, Ikeda H, Bai X, Minoda Y, Esaki M, Tanaka Y, Chinen T, Ogawa Y.
- Journal Title
  
  Esophagus
  
  Volume: 19 Issue: 2 Pages: 332-342
- DOI
  10.1007/s10388-021-00887-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08334, KAKENHI-PROJECT-16K21751
[Journal Article] Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows2021
- Author(s)
  Muta K, Ihara E, Hamada S, Ikeda H, Wada M, Hata Y, Bai X, Nishihara Y, Tanaka Y, Ogino H and Ogawa Y
- Journal Title
  
  Scientific Report (In press)
  
  Volume: なし
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08334
[Journal Article] Involvement of interstitial cells of Cajal in nicotinic acetylcholine receptor-induced relaxation of the porcine lower esophageal sphincter2021
- Author(s)
  Otsuka, Y. Bai, X. Tanaka, Y. Ihara, E. Chinen, T. Ogino, H. Ogawa, Y.
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 910 Pages: 174491-174491
- DOI
  10.1016/j.ejphar.2021.174491
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08334, KAKENHI-PROJECT-16K21751
[Journal Article] Autoimmune gastrointestinal dysmotility: the interface between clinical immunology and neurogastroenterology.2020
- Author(s)
  Nakane S, Mukaino A, Ihara E, Ogawa Y.
- Journal Title
  
  Immunol Med.
  
  Volume: 1 Issue: 2 Pages: 1-12
- DOI
  10.1080/25785826.2020.1797319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17012, KAKENHI-PROJECT-19H03549
[Journal Article] Clinical characterization of vonoprazan-refractory gastroesophageal reflux disease.2019
- Author(s)
  Hamada S, Ihara E, Ikeda H, Muta K, Ogino H, Chinen T, Tanaka Y, Ogawa Y
- Journal Title
  
  Digestion
  
  Volume: In press Issue: 2 Pages: 197-204
- DOI
  10.1159/000503340
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09351, KAKENHI-PROJECT-16K21751
[Journal Article] Involvement of different receptor subtypes in prostaglandin e2-induced contraction and relaxation in the lower esophageal sphincter and esophageal body.2019
- Author(s)
  Bai X, Ihara E, Otsuka Y, Tsuruta S, Hirano K, Tanaka Y, Ogino H, Hirano M, Chinen T, Akiho H, Nakamura K, Oda Y, Ogawa Y
- Journal Title
  
  Eur J Pharmacol
  
  Volume: 857 Pages: 172405-172405
- DOI
  10.1016/j.ejphar.2019.172405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09351, KAKENHI-PROJECT-16K21751
[Journal Article] Mucosally Expressed Cytokines are Associated with the Esophageal Motility Function.2018
- Author(s)
  Fukaura K, Ihara E, Ogino H, Iboshi Y, Muta K, Xiaopeng B, Hamada S, Hata Y, Iwasa T, Aso A, Nakamura K, Ogawa Y.
- Journal Title
  
  Digestion
  
  Volume: 98 Issue: 2 Pages: 95-103
- DOI
  10.1159/000487708
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09351
[Journal Article] Diagnosis and Treatment Strategy of Achalasia Subtypes and Esophagogastric Junction Outflow Obstruction Based on High-Resolution Manometry.2017
- Author(s)
  Ihara E, Muta K, Fukaura K, Nakamura K.
- Journal Title
  
  Digestion.
  
  Volume: 95 Issue: 1 Pages: 29-35
- DOI
  10.1159/000452354
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460940
[Journal Article] Trypsin induces biphasic muscle contraction and relaxation via transient receptor potential vanilloid 1 and neurokinin receptors 1/2 in porcine esophageal body.2017
- Author(s)
  Xiaopeng B, Tanaka Y, Ihara E, Hirano K, Nakano K, Hirano M, Oda Y, Nakamura K.
- Journal Title
  
  Eur J Pharmacol.
  
  Volume: 797 Pages: 65-74
- DOI
  10.1016/j.ejphar.2017.01.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460940
[Journal Article] Clinical characteristics associated with esophageal motility function.2016
- Author(s)
  Tanaka Y, Ihara E, Nakamura K, Muta K, Fukaura K, Mukai K, Bai X, Takayanagi R.
- Journal Title
  
  J Gastroenterol Hepatol.
  
  Volume: 31 Issue: 6 Pages: 1133-1140
- DOI
  10.1111/jgh.13262
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460940
[Journal Article] Effects of Acotiamide on the Esophageal Motility Function in Patients with Esophageal Motility Disorders: A Pilot Study.2016
- Author(s)
  Muta K, Ihara E, Fukaura K, Tsuchida O, Ochiai T, Nakamura K.
- Journal Title
  
  Digestion.
  
  Volume: 94 Issue: 1 Pages: 9-16
- DOI
  10.1159/000447010
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460940
[Journal Article] Trypsin-induced biphasic regulation of tone in the porcine lower esophageal sphincter.2015
- Author(s)
  Tanaka Y, Ihara E, Hirano K, Takahashi S, Hirano M, Nakamura K, Akiho H, Oda Y, Takayanagi R
- Journal Title
  
  European Journal of Pharmacology
  
  Volume: 752 Pages: 97-105
- DOI
  10.1016/j.ejphar.2015.02.008
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] Novel approach to functional dysphagia by Onigiri esophagography2023
- Author(s)
  牟田和正，水流大尭，和田将史，畑佳孝，伊原栄吉
- Organizer
  第77回日本食道学会学術集会
- Data Source
  KAKENHI-PROJECT-23K07440
[Presentation] Usefulness of onigiri esophagography combined with an obstruction level classification system in screening esophageal motility disorders2021
- Author(s)
  Ihara E, Hamada S, Muta K, Wada M, Hata Y, Ikeda H, Tanaka Y, Ogino H, Chinen T, Ogawa Y.
- Organizer
  Digestive Disease Week 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08334
[Presentation] Usefulness of barium esophagram with newly developed wave appearance in screening tool for esophageal motility disorders.2020
- Author(s)
  Hata Y, Hamada S, Wada M, Ikeda H, Komori K, Ogino H, Ihara E, Akiho H and Ogawa Y
- Organizer
  Digestive Disease Week 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K08334
[Presentation] 下部食道括約筋部の粘膜及び筋層組織に発現するサイトカインプロファイルによるアカラシアサブタイプの病態解析2019
- Author(s)
  向井康二、伊原栄吉、鬼丸学、井上晴洋、小川佳宏
- Organizer
  第61日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-17K09351
[Presentation] Mucosally expressed protease-activated receptor2 and transient receptor potential vanilloid1 are associated with functional heartburn.2018
- Author(s)
  Muta K, Ihara E, Hamada S, Fukaura K, Bai X, Otsuka Y, Ogino H, Bai X, Mukai K, Komori K, Hata Y, Mukai K, Komori K, Iwasa T, Akiho H, Nakamura K and Ogawa Y
- Organizer
  Digestive Disease Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09351
[Presentation] Nicotine caused the dual regulation of tone in the porcine lower esophageal sphincter through excitatory and inhibitory enteric innervation.2018
- Author(s)
  Bai X, Ihara E, Otsuka Y, Ogino H, Akiho H, Nakamura K and Ogawa Y
- Organizer
  Digestive Disease Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09351
[Presentation] Both incomplete LES relaxation and premature contraction of esophageal body are characteristics of dry swallow.2018
- Author(s)
  Muta K, Ihara E, Fukaura K, Bai X, Hata Y, Ogino H, Ochiai T, Nakamura K and Ogawa Y
- Organizer
  Digestive Disease Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09351
[Presentation] The esophageal intraluminal baseline impedance differentiates reflux hypersensitivity from NERD.2018
- Author(s)
  Hamada S, Ihara E, Muta K, Fukaura K, Ogino H, Bai X, Mukai K, Otsuka Y, Komori K, Hata Y, Aso A, Iwasa T, Ochiai T, Akiho H, Nakamura K and Ogawa Y
- Organizer
  Digestive Disease Week 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09351
[Presentation] Mechanisms of acotiamde-sensitive impaired lower esophageal sphincter accommodation in patients with esophagogastric junction outflow obstruction.2016
- Author(s)
  Muta K, Ihara E, Fukaura K, Bai X, Tanaka Y, Tsuchida O, Ochiai T, Iwasa T, Aso A, Nakamura K.
- Organizer
  Digestive Disease Week
- Place of Presentation
  San Diego
- Year and Date
  2016-05-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] Mechanisms of acotiamide-sensitive impaired lower esophageal sphincter accommodation in patients with esophagogastric junction outflow obstruction2016
- Author(s)
  Muta K, Ihara E, Fukaura K, Bai X, Tanaka Y, Tsuchida O, Ochiai T, Iwasa T, Aso A and Nakamura K
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  San Diego
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] Actiamide has the potential to become a promising treatment for patients with esophagogastric junction outflow obstruction.2015
- Author(s)
  Muta K, Ihara E, Fukaura K, Bai X, Tanaka Y, Nakamura K, Ochiai T, Tsuchida O, Akiho H, Takayanagi R.
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Washington DC
- Year and Date
  2015-05-17
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] Clinical characteristics associated with function of esophageal motility: A retrospective analysis of 97 patients.2015
- Author(s)
  Tanaka Y, Ihara E, Muta K, Fukaura K, Mukai K, Bai X, Nakamura K, Akiho H, Takayanagi R.
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Washington DC
- Year and Date
  2015-05-17
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] The cytokine expression patterns of esophageal mucosa are associated with esophageal motility function in human.2015
- Author(s)
  Fukaura K, Ihara E, Muta K, Tanaka Y, Bai X, Nakamura K, Takayanagi R.
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Washington DC
- Year and Date
  2015-05-17
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] Endogenous H2S contributes to myogenic tone generation in lower esophageal sphincter: Possible involvement of Na+/Ca2+ exchanger.2015
- Author(s)
  Bai X, Ihara E, Tanaka Y, Hirano K, Hirano M, Akiho H, Nakamura K, Takayanagi R.
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Washington DC
- Year and Date
  2015-05-17
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] 消化管免疫と消化管平滑筋収縮性変化2013
- Author(s)
  伊原栄吉
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市
- Data Source
  KAKENHI-PROJECT-23890149
[Presentation] Clinical characteristics associated with function of esophageal motility: A retrospective analysis of 97 patients
- Author(s)
  Tanaka Y, Ihara E, Muta K, Fukaura K, Mukai K, Bai X, Nakamura K, Takayanagi R
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Washington
- Year and Date
  2015-05-16 – 2015-05-20
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] The cytokine expression patterns of esophageal mucosa are associated with esophageal motility function in human.
- Author(s)
  Fukaura K, Ihara E, Muta K, Tanaka Y, Bai X, Nakamura K, Takayanagi R
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Washington
- Year and Date
  2015-05-16 – 2015-05-20
- Data Source
  KAKENHI-PROJECT-26460940
[Presentation] Endogenous H2S contributes to myogenic tone generation in lower esophageal sphincter: possible involvement of Na+/Ca2+ exchanger
- Author(s)
  Bai X, Ihara E, Tanaka Y, Hirano K, Hirano M, Nakamura K, Takayanagi R
- Organizer
  Digestive Disease Week (DDW)
- Place of Presentation
  Washington
- Year and Date
  2015-05-16 – 2015-05-20
- Data Source
  KAKENHI-PROJECT-26460940

1. NAKAMURA Kazuhiko (00274449)

# of Collaborated Projects: 4 results

# of Collaborated Products: 14 results
2. Nakane Shunya (70398022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 池田徳典 (00613530)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 佐藤伸一 (20215792)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田村直人 (20227284)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 樋口理 (50361720)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 鈴木隆二 (70373470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 坪井洋人 (80580505)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 宋文杰 (90216573)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 川上純 (90325639)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 佐藤和貴郎 (90469990)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. UEDA Mitsuharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 小川佳宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
14. 向野晃弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 安東由喜雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ihara Eikichi 伊原 栄吉

IHARA Eikichi 伊原 栄吉

Research Projects

Research Products

Co-Researchers

Establishing disease concept of new type of esophageal motility dysfunction due to altered distention and elucidation of its pathogenesisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of esophageal achalasia based on their subtypes from the multiple perspectives.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Multidisciplinary analysis of heterogeneity in autoimmune autonomic ganglionopathy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Determination of underlying cause of esophageal achalasia by the use of cytokine profilesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Induction of the cell surface-bound TGF-beta on the regulatory T cells by enteric bacteria and its fermentation product.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Investigation of myogenic tone regulation in lower esophageal sphincter to develop novel treatments for achalasiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The mechanism of increased smad7 expression in the intestinal mucosa of inflammatory bowel disease and the exploitation of a new therapy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Effects of IL-23 and Th17 on intestinal smooth muscle contractility and its underlying mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] The interplay between alterations in esophageal microbiota associated with th17 immune response and impaired LC20 phosphorylation in achalasia.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Determination of Region-Specific Roles of the M3 Muscarinic Acetylcholine Receptor in Gastrointestinal Motility2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Improved esophagography screening for esophageal motility disorders using wave appearance and supra-junctional ballooning2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A novel murine model of autoimmune dysautonomia by α3 nicotinic acetylcholine receptor immunization2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The treatment effects of acotiamide in esophagogastric outflow obstruction: A prospective longitudinal observational study.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Physiological and pathological roles of the accommodation response in lower esophageal sphincter relaxation during wet swallows2021

Author(s)

Ihara Eikichi 伊原栄吉

IHARA Eikichi 伊原栄吉