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Ohhata Tatsuya  大畑 樹也

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OHHATA Tatsuya  大畑 樹也

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Researcher Number 80616459
Other IDs
Affiliation (Current) 2020: 浜松医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2014 – 2020: 浜松医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Molecular biology / Basic Section 43030:Functional biochemistry-related
Except Principal Investigator
Tumor biology / Molecular biology
Keywords
Principal Investigator
エピジェネティクス / X染色体不活性化 / ノンコーディングRNA / 非コードRNA / アンチセンスRNA / cisNATs / X染色体の不活性化 / 長鎖非コードRNA / 多能性細胞 / Xist … More / Tsix / ヘテロクロマチン / クロマチン / ダイナミクス / lncRNA / TGFβ / EMT … More
Except Principal Investigator
lncRNA / cancer / ノンコーディングRNA / 癌 / 相同組換え / X染色体不活性化 / 染色体構築・機能・分配 Less
  • Research Projects

    (5 results)
  • Research Products

    (27 results)
  • Co-Researchers

    (4 People)
  •  TGFβに応答する機能性cis-NATs群の生理・分子機構の解明Principal InvestigatorOngoing

    • Principal Investigator
      大畑 樹也
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43030:Functional biochemistry-related
    • Research Institution
      Hamamatsu University School of Medicine
  •  Elucidation of transcription-coupled facultative heterochromatin dynamicsPrincipal Investigator

    • Principal Investigator
      Ohhata Tatsuya
    • Project Period (FY)
      2016 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Molecular biology
    • Research Institution
      Hamamatsu University School of Medicine
  •  Regulatory mechanism of homologous recombination in a Sex-chromosome-dependent manner

    • Principal Investigator
      Kitagawa Masatoshi
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Molecular biology
    • Research Institution
      Hamamatsu University School of Medicine
  •  Functional screening of the genes involved in Xist function and pluripotencyPrincipal Investigator

    • Principal Investigator
      OHHATA Tatsuya
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Molecular biology
    • Research Institution
      Hamamatsu University School of Medicine
  •  Long non-coding RNA associated with cancer stemness

    • Principal Investigator
      KITAGAWA Masatoshi
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Tumor biology
    • Research Institution
      Hamamatsu University School of Medicine

All 2019 2018 2017 2016 2015 2014

All Journal Article Presentation Book

  • [Book] lncRNAと疾患, ノンコーディングRNA -RNA分子の全体像を俯瞰する-2016

    • Author(s)
      大畑樹也
    • Total Pages
      12
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Book] DOJIN BIOSCIENCEシリーズ 非コードRNA (第29章:lncRNAと疾患)2016

    • Author(s)
      大畑樹也(廣瀬哲郎・泊幸秀編)
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Book] ノンコーディングRNA -RNA分子の全体像を俯瞰する-2016

    • Author(s)
      大畑樹也
    • Total Pages
      12
    • Publisher
      化学同人
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Journal Article] Long Non-coding RNA, PANDA, Contributes to the Stabilization of p53 Tumor Suppressor Protein.2016

    • Author(s)
      Kotake Y, Kitagawa K, Ohhata T, Sakai S, Uchida C, Niida H, Naemura M, Kitagawa M.
    • Journal Title

      Anticancer Res.

      Volume: 36 Pages: 1605-1611

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-26640073
  • [Journal Article] Histone H3 Lysine 36 Trimethylation Is Established over the Xist Promoter by Antisense Tsix Transcription and Contributes to Repressing Xist Expression.2015

    • Author(s)
      Ohhata T, Matsumoto M, Leeb M, Shibata S, Sakai S, Kitagawa K, Niida H, Kitagawa M, Wutz A.
    • Journal Title

      Mol Cell Biol.

      Volume: 35 Pages: 3909-3920

    • DOI

      10.1128/mcb.00561-15

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] Dynamics from euchromatin to facultative heterochromatin in local gene silencing2019

    • Author(s)
      Tatsuya Ohhata
    • Organizer
      第6回北陸エピジェネティクス研究会
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] 単一遺伝子座における条件的ヘテロクロマチンダイナミクス2019

    • Author(s)
      Tatsuya Ohhata, Kazuki Yamasawa, Asuka Miura-kamio, Saori Takahashi, Ichiro Hiratani, Hisato Kobayashi, Hiroshi Kimura, Anton Wutz, Masatoshi Kitagawa
    • Organizer
      第42回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] A snapshot of facultative heterochromatin dynamics revealed by antisense long non-coding RNA Tsix2018

    • Author(s)
      大畑 樹也
    • Organizer
      第6回 X染色体研究会
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] A snapshot of facultative heterochromatin dynamics revealed by antisense long non-coding RNA Tsix2018

    • Author(s)
      大畑 樹也
    • Organizer
      第41回 日本分子生物学会
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] Dynamics of faclutative heterochromatin formation at the Xist promoter evoked by antisense long non-coding RNA Tsix2017

    • Author(s)
      Tatsuya Ohhata, Hiroshi Kimura, Kazuki Yamazawa, Anton Wutz, Masatoshi Kitagawa
    • Organizer
      The 43rd Naito Conference on "Noncoding RNA: Biology, Chemistry, & Diseases"
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] A snapshot of facultative heterochromatin dynamics revealed by antisense long non-coding RNA Tsix2017

    • Author(s)
      大畑 樹也
    • Organizer
      第5回 X染色体研究会
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] アンチセンス非コードRNA Tsix による条件的ヘテロクロマチン形成機構の動的解析2017

    • Author(s)
      Tatsuya Ohhata, Hiroshi Kimura, Kazuki Yamazawa, Anton Wutz, Masatoshi Kitagawa
    • Organizer
      第11回 日本エピジェネティクス研究会
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] Dynamics of repressive chromatin conformation at the Xist promoter revealed by Tsix-inducible system2017

    • Author(s)
      Tatsuya Ohhata
    • Organizer
      第22回浜松医科学シンポジウム
    • Place of Presentation
      浜松市、静岡県
    • Year and Date
      2017-03-10
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] A snapshot of facultative heterochromatin dynamics revealed by antisense long non-coding RNA Tsix2017

    • Author(s)
      Tatsuya Ohhata, Hiroshi Kimura, Kazuki Yamazawa, Asuka Miura-Kamio, Hisato Kobayashi, Anton Wutz, Masatoshi Kitagawa
    • Organizer
      Gordon Research Conference, Epigenetics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] A snapshot of facultative heterochromatin dynamics revealed by antisense long non-coding RNA Tsix2017

    • Author(s)
      大畑 樹也
    • Organizer
      第4回 北陸エピジェネティクス研究会
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] 条件的ヘテロクロマチン形成機構の解明を目指して2016

    • Author(s)
      大畑樹也
    • Organizer
      第一回浜松医科大学学内研究交流会
    • Place of Presentation
      舘山寺温泉、浜松市
    • Year and Date
      2016-07-17
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] Investigating the molecular mechanisms of Tsix antisense RNA involved in the Regulation of X-chromosome inactivation2016

    • Author(s)
      Tatsuya Ohhata
    • Organizer
      第3回北陸エピジェネティクス研究会
    • Place of Presentation
      福井市、福井県
    • Year and Date
      2016-11-21
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] アンチセンスRNA TsixはH3K36me3をXistプロモーターに導入しXistの発現を抑制する2016

    • Author(s)
      大畑樹也、松本美香、Martin Leeb、柴田進和、北川恭子、丹伊田浩行、酒井聡、Anton Wutz、北川雅敏
    • Organizer
      第39回日本分子生物学会年会
    • Place of Presentation
      横浜市、神奈川県
    • Year and Date
      2016-11-30
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] Dynamics of repressive chromatin conformation at the Xist promoter revealed by Tsix-inducible system2016

    • Author(s)
      Tatsuya Ohhata
    • Organizer
      X chromosome inactivation -A tribute to Mary Lyon-
    • Place of Presentation
      Royal society, London, UK
    • Year and Date
      2016-10-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] 条件的ヘテロクロマチン形成機構の解明を目指して2016

    • Author(s)
      大畑樹也
    • Organizer
      第1回浜松医科大学学内研究交流会
    • Place of Presentation
      舘山寺温泉、浜松市
    • Year and Date
      2016-07-17
    • Data Source
      KAKENHI-PROJECT-16K07249
  • [Presentation] Tsixの機能解明に向けての現状と展望2016

    • Author(s)
      大畑樹也
    • Organizer
      X染色体研究会
    • Place of Presentation
      鳥取県米子市
    • Year and Date
      2016-03-25
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] Histone H3 lysine 36 tri-methylation is established over the Xist promoter by antisense Tsix transcription and has a role in preventing Xist expression.2015

    • Author(s)
      Tatsuya Ohhata
    • Organizer
      nternational Symposium on Non-coding DNA and Chromosomal Integrity.
    • Place of Presentation
      Awaji-shi, Hyogo-ken, JAPAN
    • Year and Date
      2015-08-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] アンチセンスRNA TsixはH3K36me3をXistプロモーターに導入しXistの発現を抑制している2015

    • Author(s)
      大畑樹也
    • Organizer
      日本RNA学会
    • Place of Presentation
      北海道札幌市
    • Year and Date
      2015-07-16
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] Tsix発現誘導細胞を用いたTsix分子機構の解析2015

    • Author(s)
      大畑樹也
    • Organizer
      X染色体研究会
    • Place of Presentation
      近畿大学(奈良県奈良市)
    • Year and Date
      2015-03-27
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] 未分化ES細胞のXist発現抑制機構2014

    • Author(s)
      大畑樹也
    • Organizer
      日本分子生物学会
    • Place of Presentation
      パシフィコ横浜(神奈川県横浜市)
    • Year and Date
      2014-11-27
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] マウスES細胞におけるXistの発現抑制機構2014

    • Author(s)
      大畑樹也
    • Organizer
      日本遺伝学会
    • Place of Presentation
      長浜バイオ大学(滋賀県長浜市)
    • Year and Date
      2014-09-17
    • Data Source
      KAKENHI-PROJECT-26840006
  • [Presentation] X染色体不活性化を調節するノンコーディングRNA Tsixによる遺伝子発現制御機構2014

    • Author(s)
      大畑樹也
    • Organizer
      名市大エピジェネティクス研究会
    • Place of Presentation
      長野県南木曽町
    • Year and Date
      2014-09-04
    • Invited
    • Data Source
      KAKENHI-PROJECT-26840006
  • 1.  KITAGAWA Masatoshi (50294971)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  KITAGAWA Kyoko (20299605)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  NIIDA Hiroyuki (20336671)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  UCHIDA Chiharu (60223567)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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