KAWAHARA MASAHIRO 河原真大

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KAWAHARA Masahiro 河原真大

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Researcher Number	80617449
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 非常勤講師 2025: 京都大学, 医学研究科, 特定病院助教
Affiliation (based on the past Project Information) *help	2017 – 2021: 滋賀医科大学, 医学部, 講師 2018: 滋賀医科大学, 医学部, 助教 2015 – 2016: 滋賀医科大学, 医学部, 助教 2012 – 2014: 京都大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related / Biological Sciences
Keywords	Principal Investigator 白血病 / 転写因子 / ヒストン修飾 / 造血分化 / 血球分化 / ヒストン脱メチル化酵素 / 造血幹細胞 / キメラ遺伝子 / スーパーエンハンサー / Super-enhancer … More / Transcription Factor / Leukemia / LSD1 / エンハンサー / DNA損傷ストレス / ヒストンメチル化 / 新規阻害剤 / KDM1A / 骨髄異形成症候群 / MLF1 / NPM1 Less

Alteration of transcription network via super-enhancer in acute leukemiaPrincipal Investigator
- Principal Investigator
  
  Kawahara Masahiro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Shiga University of Medical Science
Identification and regulation mechanism of enhancers for hematopoietic cell fate decisionPrincipal Investigator
- Principal Investigator
  
  Kawahara Masahiro
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Shiga University of Medical Science
Alteration of stress response by a histone methylation abnormality in hematopoietic stem cellsPrincipal Investigator
- Principal Investigator
  
  KAWAHARA MASAHIRO
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Shiga University of Medical Science
  Kyoto University
ヒストン脱メチル化酵素(KDM)による造血分化制御機構の解明Principal Investigator
- Principal Investigator
  
  河原真大
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Analysis of leukemogenesis through the NPM fusion genePrincipal Investigator
- Principal Investigator
  
  KAWAHARA Masahiro
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] BIO Clinica2012
- Author(s)
  河原　真大
- Total Pages
  5
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-24790971
[Book] BIO Clinica 多遺伝子疾患, 「急性骨髄性白血病における疾患遺伝子研究」の項2012
- Author(s)
  河原真大
- Publisher
  北隆館
- Data Source
  KAKENHI-PROJECT-24790971
[Journal Article] Thiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15R138C Knock-In Mice2021
- Author(s)
  Imai T.、Kawahara M.、Tatsumi G.、Yamashita N.、Nishishita-Asai A.、Inatomi O.、Masamune A.、Kakuta Y.、Andoh A.
- Journal Title
  
  Cellular and Molecular Gastroenterology and Hepatology
  
  Volume: 12 Issue: 1 Pages: 335-337
- DOI
  10.1016/j.jcmgh.2021.03.006
- NAID
  120007053466
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08811
[Journal Article] Targeted deletion of Atg5 in intestinal epithelial cells promotes dextran sodium sulfate-induced colitis2021
- Author(s)
  Nishino Kyohei、Nishida Atsushi、Inatomi Osamu、Imai Takayuki、Kume Shinji、Kawahara Masahiro、Maegawa Hiroshi、Andoh Akira
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 68 Issue: 2 Pages: 156-163
- DOI
  10.3164/jcbn.20-90
- NAID
  130007993417
- ISSN
  0912-0009, 1880-5086
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07909, KAKENHI-PROJECT-19K08811
[Journal Article] Acquired Coagulation Factor V Inhibitor That Was Successfully Treated with Oral Corticosteroid Therapy2021
- Author(s)
  Yokota Yoshihiro、Inatomi Osamu、Nakagawa Minami、Kakuda Kazuki、Hiroe Kousuke、Sakai Shigeki、Osaki Rie、Iwasa Masaki、Kawahara Masahiro、Kito Katsuyuki、Andoh Akira、Bamba Hiromichi
- Journal Title
  
  Intern. Med.
  
  Volume: 60 Issue: 16 Pages: 2663-2666
- DOI
  10.2169/internalmedicine.7453-21
- NAID
  130008074616
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2021-08-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08811
[Journal Article] Mucosa-associated gut microbiome in Japanese patients with functional constipation2021
- Author(s)
  Sugitani Yoshihiko、Inoue Ryo、Inatomi Osamu、Nishida Atsushi、Morishima So、Imai Takayuki、Kawahara Masahiro、Naito Yuji、Andoh Akira
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 68 Issue: 2 Pages: 187-192
- DOI
  10.3164/jcbn.20-93
- NAID
  130007993416
- ISSN
  0912-0009, 1880-5086
- Year and Date
  2021-03-01
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08811
[Journal Article] Thiopurine pharmacogenomics and pregnancy in inflammatory bowel disease2021
- Author(s)
  Andoh Akira、Kawahara Masahiro、Imai Takayuki、Tatsumi Goichi、Inatomi Osamu、Kakuta Yoichi
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 56 Issue: 10 Pages: 881-890
- DOI
  10.1007/s00535-021-01805-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08811
[Journal Article] Sodium absorption stimulator prostasin (PRSS8) has an anti-inflammatory effect via downregulation of TLR4 signaling in inflammatory bowel disease.2020
- Author(s)
  Sugitani Y, Nishida A, Inatomi O, Ohno M, Imai T, Kawahara M, Kitamura K, Andoh A
- Journal Title
  
  J Gastroenterol.
  
  Volume: 55 Issue: 4 Pages: 408-417
- DOI
  10.1007/s00535-019-01660-z
- NAID
  120006783433
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08002, KAKENHI-PROJECT-19K08811, KAKENHI-PROJECT-18K07909
[Journal Article] A case of life-threatening small intestinal bleeding accompanied by lower coagulation factor XIII activity2020
- Author(s)
  Murata, M., Inatomi, O., Ono, K., Imai, T., Iwasa, M., Kawahara, M., Kito, K., Andoh, A.
- Journal Title
  
  Clinical Journal of Gastroenterology
  
  Volume: 13 Issue: 6 Pages: 1178-1182
- DOI
  10.1007/s12328-020-01195-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08811
[Journal Article] Thiopurine-mediated impairment of hematopoietic stem and leukemia cells in Nudt15R138C knock-in mice.2020
- Author(s)
  Tatsumi G, Kawahara M*, Imai T, Nishishita-Asai A, Nishida A, Inatomi O, Yokoyama A, Kakuta Y, Kito K, Andoh A
- Journal Title
  
  Leukemia
  
  Volume: 34 Issue: 3 Pages: 882-894
- DOI
  10.1038/s41375-019-0583-9
- NAID
  120006768264
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08811, KAKENHI-PROJECT-19H03694
[Journal Article] LSD1-mediated repression of GFI1 super-enhancer plays an essential role in erythroleukemia2020
- Author(s)
  Tatsumi G, Kawahara M, Yamamoto R, Hishizawa M, Kito K, Suzuki T, Takaori-Kondo A, Andoh A
- Journal Title
  
  Leukemia.
  
  Volume: 34 Issue: 3 Pages: 746-758
- DOI
  10.1038/s41375-019-0614-6
- NAID
  120006768263
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08002, KAKENHI-PROJECT-19K08811, KAKENHI-PROJECT-19H01079
[Journal Article] Elemental diet induces alterations of the gut microbial community in mice2019
- Author(s)
  Andoh A, Inoue R, Kawada Y, Morishima S, Inatomi O, Ohno M, Bamba S, Nishida A, Kawahara M, Naito Y
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 65 Issue: 2 Pages: 118-124
- DOI
  10.3164/jcbn.19-8
- NAID
  130007700227
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08811
[Journal Article] pH-Dependent 5-Aminosalicylates Releasing Preparations Do Not Affect Thiopurine Metabolism2019
- Author(s)
  Takahashi Kenichiro、Bamba Shigeki、Morita Yasuhiro、Nishida Atsushi、Kawahara Masahiro、Inatomi Osamu、Sugimoto Mitsushige、Sasaki Masaya、Andoh Akira
- Journal Title
  
  Digestion
  
  Volume: 2 Issue: 4 Pages: 1-9
- DOI
  10.1159/000495690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K10990, KAKENHI-PROJECT-16K09846
[Journal Article] Astaxanthin, a xanthophyll carotenoid, prevents development of dextran sulphate sodium-induced murine colitis2019
- Author(s)
  Sakai S, Nishida A, Ohno M, Inatomi O, Bamba S, Sugimoto M, Kawahara M, Andoh A.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 64 Issue: 1 Pages: 66-72
- DOI
  10.3164/jcbn.18-47
- NAID
  130007542255
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] Characterization of fungal dysbiosis in Japanese patients with inflammatory bowel disease.2019
- Author(s)
  Imai T, Inoue R, Kawada Y, Morita Y, Inatomi O, Nishida A, Bamba S, Kawahara M, Andoh A.
- Journal Title
  
  J Gastroenterol.
  
  Volume: 54 Issue: 2 Pages: 149-159
- DOI
  10.1007/s00535-018-1530-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] Effect of fermented vegetable beverage containing Pediococcus pentosaceus in patients with mild to moderate ulcerative colitis.2018
- Author(s)
  Bamba S, Takahashi K, Imaeda H, Nishida A, Kawahara M, Inatomi O, Sugimoto M, Sasaki M, Andoh A.
- Journal Title
  
  Biomed Rep.
  
  Volume: 9 Pages: 74-80
- DOI
  10.3892/br.2018.1099
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] 初診時脳内出血を伴う急性骨髄性白血病の中枢神経病変管理における髄液細胞数モニタリングの有用性.2018
- Author(s)
  河原真大, 寺本由加子, 浅井愛, 永井詩穂, 岩佐磨佐紀, 藤城綾, 西村理恵, 南口仁志, 辻篤司, 木藤克之, 安藤　朗.
- Journal Title
  
  臨床血液
  
  Volume: 59 Pages: 2578-2582
- NAID
  130007554686
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] A novel mutation causing type 1 Gaucher disease found in a Japanese patient with gastric cancer: A case report.2018
- Author(s)
  Hosoba S, Kito K, Teramoto Y, Adachi K, Nakanishi R, Asai A, Iwasa M, Nishimura R, Moritani S, Kawahara M, Minamiguchi H, Nanba E, Kushima R, Andoh A.
- Journal Title
  
  Medicine (Baltimore)
  
  Volume: 97 Issue: 27 Pages: e11361-e11361
- DOI
  10.1097/md.0000000000011361
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] Magnified single-balloon enteroscopy in the diagnosis of intestinal follicular lymphoma: a case series.2018
- Author(s)
  Takahashi K, Bamba S, Kawahara M, Nishida A, Inatomi O, Sasaki M, Tsujikawa T, Kushima R, Sugimoto M, Kitoh K, Andoh A.
- Journal Title
  
  Intest Res.
  
  Volume: 16 Issue: 4 Pages: 628-634
- DOI
  10.5217/ir.2018.00003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] Selective dissociation between LSD1 and GFI1B by a LSD1 inhibitor NCD38 induces the activation of ERG super-enhancer in erythroleukemia cells.2018
- Author(s)
  Yamamoto R, Kawahara M, Ito S, Satoh J, Tatsumi G, Hishizawa M, Suzuki T, Andoh A.
- Journal Title
  
  Oncotarget
  
  Volume: 印刷中 Issue: 30 Pages: 21007-21021
- DOI
  10.18632/oncotarget.24774
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] Ameliorating effects of bortezomib, a proteasome inhibitor, on development of dextran sulfate sodium-induced murine colitis2018
- Author(s)
  Sakai S, Nishida A, Ohno M, Inatomi O, Bamba S, Sugimoto M, Kawahara M, Andoh A.
- Journal Title
  
  Journal of Clinical Biochemistry and Nutrition
  
  Volume: 63 Issue: 3 Pages: 217-223
- DOI
  10.3164/jcbn.18-42
- ISSN
  0912-0009, 1880-5086
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] MicroRNA-33 regulates the population of peripheral inflammatory Ly6Chigh monocytes through dual pathways.2018
- Author(s)
  Baba O, Horie T, Hakuno D, Nakashima Y, Nishi H, Kuwabara Y, Nakao T, Nishiga M, Nishino T, Ide Y, Nakazeki F, Koyama S, Kimura M, Hanada R, Kawahara M, Kimura T, and Ono K.
- Journal Title
  
  Mol Cell Biol.
  
  Volume: 38 Issue: 14 Pages: 1-17
- DOI
  10.1128/mcb.00604-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09846, KAKENHI-PROJECT-17K16002, KAKENHI-PUBLICLY-17H05599, KAKENHI-PROJECT-17H04177, KAKENHI-PROJECT-17K19590, KAKENHI-PROJECT-17K09860
[Journal Article] Analysis of endoscopic brush samples identified mucosa-associated dysbiosis in inflammatory bowel disease.2018
- Author(s)
  Nishino K, Nishida A, Inoue R, Kawada Y, Ohno M, Sakai S, Inatomi O, Bamba S, Sugimoto M, Kawahara M, Naito Y, Andoh A
- Journal Title
  
  J Gastroenterol.
  
  Volume: 53 Issue: 1 Pages: 95-106
- DOI
  10.1007/s00535-017-1384-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846, KAKENHI-PROJECT-15K08948
[Journal Article] Expression of Interleukin-26 is upregulated in inflammatory bowel disease.2017
- Author(s)
  Fujii M, Nishida A, Imaeda H, Ohno M, Nishino K, Sakai S, Inatomi O, Bamba S, Kawahara M, Shimizu T, Andoh A
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 23 Issue: 30 Pages: 5519-5529
- DOI
  10.3748/wjg.v23.i30.5519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09846, KAKENHI-PROJECT-15K19322
[Journal Article] Nanoparticle curcumin ameliorates experimental colitis via modulation of gut microbiota and induction of regulatory T cells.2017
- Author(s)
  Ohno M, Nishida A, Sugitani Y, Nishino K, Inatomi O, Sugimoto M, Kawahara M, Andoh A
- Journal Title
  
  PLoS One
  
  Volume: 12 Issue: 10 Pages: e0185999-e0185999
- DOI
  10.1371/journal.pone.0185999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09846, KAKENHI-PROJECT-15K08948
[Journal Article] Central nervous system involvement of acute promyelocytic leukemia, three case reports2017
- Author(s)
  Aya Furuya, Masahiro Kawahara*, Mina Kumode, Yasuyuki Ohira, Asako Usui, Shiho Nagai, Sakura Hosoba, Hitoshi Minamiguchi, Katsuyuki Kito & Akira Andoh (* correspondence)
- Journal Title
  
  Clinical Case Reports
  
  Volume: 印刷中 Issue: 5 Pages: 645-653
- DOI
  10.1002/ccr3.919
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09846
[Journal Article] A novel LSD1 inhibitor NCD38 ameliorates MDS-related leukemia with complex karyotype by attenuating leukemia programs via activating super-enhancers.2017
- Author(s)
  Sugino N, Kawahara M, Tatsumi G, Kanai A, Matsui H, Yamamoto R, Nagai Y, Fujii S, Shimazu Y, Hishizawa M, Inaba T, Andoh A, Suzuki T, Takaori-Kondo A.
- Journal Title
  
  Leukemia
  
  Volume: in press Issue: 11 Pages: 2303-2314
- DOI
  10.1038/leu.2017.59
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-15H01513, KAKENHI-PROJECT-15K16125, KAKENHI-PROJECT-16K09846, KAKENHI-PUBLICLY-17H05649, KAKENHI-PROJECT-15H04857, KAKENHI-PROJECT-15K09478
[Journal Article] Expression of human cathelicidin peptide LL-37 in inflammatory bowel disease.2017
- Author(s)
  Kusaka S, Nishida A, Takahashi K, Bamba S, Yasui H, Kawahara M, Inatomi O, Sugimoto M, Andoh A
- Journal Title
  
  Clin Exp Immunol.
  
  Volume: 191 Issue: 1 Pages: 96-106
- DOI
  10.1111/cei.13047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K09846, KAKENHI-PROJECT-15K08948, KAKENHI-PROJECT-15K19322
[Journal Article] Hypomethylation of the Treg-specific demethylated region in FOXP3 is a hallmark of the regulatory T-cell subtype in adult T-cell leukemia2016
- Author(s)
  Shimazu Y, Shimazu Y, Hishizawa M, Hamaguchi M, Nagai Y, Sugino N, Fujii S, Kawahara M, Kadowaki N, Nishikawa H, Sakaguchi S, Takaori-Kondo A
- Journal Title
  
  Cancer Immunol Res
  
  Volume: 4 Issue: 2 Pages: 136-145
- DOI
  10.1158/2326-6066.cir-15-0148
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09501, KAKENHI-PROJECT-26670581, KAKENHI-PROJECT-26860729, KAKENHI-PROJECT-26290054, KAKENHI-PROJECT-16K09846
[Journal Article] A Japanese family with X-linked sideroblastic anemia affecting females and manifesting as macrocytic anemia.2016
- Author(s)
  1)Katsurada T, Kawabata H, Kawabata D, Kawahara M, Nakabo Y, Takaori-Kondo A, Yoshida Y.
- Journal Title
  
  Int J Hematol.
  
  Volume: E-pub
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860729
[Journal Article] T memory stem cells are the hierarchical apex of adult T-cell leukemia.2015
- Author(s)
  Yuya Nagai†, Masahiro Kawahara†, Masakatsu Hishizawa, Yayoi Shimazu, Noriko Sugino, Sumie Fujii, Norimitsu Kadowaki and Akifumi Takaori-Kondo. (†These authors contributed equally to this work.)
- Journal Title
  
  Blood
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118713
[Journal Article] T memory stem cells are the hierarchical apex of adult T-cell leukemia2015
- Author(s)
  Nagai Y, Kawahara M, Hishizawa M, Shimazu Y, Sugino N, Fujii S, Kadowaki N, Takaori-Kondo A
- Journal Title
  
  Blood
  
  Volume: 125 Issue: 23 Pages: 3527-3535
- DOI
  10.1182/blood-2014-10-607465
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K09501, KAKENHI-PLANNED-24115004, KAKENHI-PROJECT-26860729
[Journal Article] T memory stem cells are the hierarchical apex of adult T-cell leukemia2015
- Author(s)
  Yuya Nagai†, Masahiro Kawahara†, Masakatsu Hishizawa, Yayoi Shimazu, Noriko Sugino, Sumie Fujii, Norimitsu Kadowaki and Akifumi Takaori-Kondo. (†These authors contributed equally to this work.)
- Journal Title
  
  Blood
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26860729
[Journal Article] A case of minor BCR-ABL1 positive acute lymphoblastic leukemia following essential thrombocythemia and originating from a clone distinct from that harboring the JAK2-V617F mutation.2014
- Author(s)
  Nagai Y, Kawahara M, Sugino N, Shimazu Y, Hishizawa M, Yamashita K, Kadowaki N, Takaori-Kondo A
- Journal Title
  
  Experimental Hematology & Oncology
  
  Volume: 3 Issue: 1 Pages: 6-6
- DOI
  10.1186/2162-3619-3-6
- NAID
  120005411358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790971, KAKENHI-PUBLICLY-25118713, KAKENHI-PROJECT-26860729
[Journal Article] Co-occurrence of monoclonal gammopathy and myelodysplasia: a retrospective study of fourteen cases.2014
- Author(s)
  1.Yoshida Y, Oguma S, Ohno H, Nakabo Y, Katsurada T, Kawahara M, Kawabata H.
- Journal Title
  
  Int J Hematol
  
  Volume: 99 Issue: 6 Pages: 721-725
- DOI
  10.1007/s12185-014-1570-6
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-25118713, KAKENHI-PROJECT-26860729
[Journal Article] Absent or Extremely Low Neutrophil Alkaline Phosphatase Activity Levels in Patients with Myelodysplastic Syndromes2013
- Author(s)
  Yoshida Y, Katsurada T, Oguma S, Nakabo Y, Yoshinaga N, Kawahara M, Kawabata H.
- Journal Title
  
  Intern. Med.
  
  Volume: 52 Issue: 4 Pages: 479-482
- DOI
  10.2169/internalmedicine.52.9114
- NAID
  130003365905
- ISSN
  0918-2918, 1349-7235
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790971, KAKENHI-PUBLICLY-25118713
[Journal Article] H2.0-like homeobox (HLX) regulates early hematopoiesis and promotes acute myeloid leukemia2012
- Author(s)
  Kawahara M, Pandolfi A, Bartholdy B, Barreyro L, Will B, Roth M, Okoye UC, Todorova T, Figueroa ME, Melnick A, Mitsiades CS, Steidl U
- Journal Title
  
  Cancer Cell
  
  Volume: 22 Issue: 2 Pages: 194-208
- DOI
  10.1016/j.ccr.2012.06.027
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24790971
[Patent] リシン構造を有するLSD1選択的阻害薬2013
- Inventor(s)
  Kawahara M 他7名
- Industrial Property Rights Holder
  国立大学法人京都大学他4機関
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-28
- Overseas
- Data Source
  KAKENHI-PROJECT-24790971
[Patent] リシン構造を有するLSD1 選択的阻害薬2013
- Inventor(s)
  河原真大, 他7名
- Industrial Property Rights Holder
  国立大学法人京都大学, 他4機関
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-28
- Overseas
- Data Source
  KAKENHI-PROJECT-24790971
[Patent] リシン構造を有するＬＳＤ1選択的阻害薬2013
- Inventor(s)
  Kawahara M　他7名
- Industrial Property Rights Holder
  国立大学法人京都大学他4機関
- Industrial Property Rights Type
  特許
- Filing Date
  2013-11-28
- Overseas
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] t(16;21) (p11;q22)を認めたAMLとMDSの2症例2021
- Author(s)
  浅井愛、田代晴加、雜賀渉、口分田美奈、永井詩穂、岩佐磨佐紀、藤城綾、西村理恵、河原真大、南口仁志、北村憲一、木藤克之、安藤朗
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] 中枢神経病変を伴う悪性リンパ腫に対するR-MPV療法の6症例2021
- Author(s)
  口分田美奈，田代晴加，雜賀渉，岩佐磨佐紀，藤城綾，西村理惠，河原真大，南口仁志，木藤克之，安藤朗
- Organizer
  第118回日本内科学会総会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] 当院で経験した特発性多中心性キャッスルマン病の 4 症例2021
- Author(s)
  西村理恵、田代晴加、雜賀渉、口分田美奈、永井詩穂、浅井愛、岩佐磨佐紀、藤城綾、河原真大、南口仁志、木藤克之、安藤朗
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] マウスモデルからみたNUDT15遺伝子多型と妊娠中のチオプリン服用2021
- Author(s)
  今井隆行、河原真大、稲富理、角田洋一、安藤朗
- Organizer
  第12回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] チオプリン製剤投与患者におけるNUDT15遺伝子多型c.416G>A (Arg139His) 変異の臨床的影響2021
- Author(s)
  磯野哲一郎、平大樹、河原真大、稲富理、安藤朗、寺田智祐、森田真也
- Organizer
  第12回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] 難治性皮膚原発末梢性T細胞リンパ腫・非特定型に対して全身皮膚電子線照射が有効であった症例2021
- Author(s)
  阿部和樹、臼井亜沙子、川畑徳浩、岩佐磨佐紀、藤城綾、西村理恵、河原真大、南口仁志、木藤克之、安藤朗
- Organizer
  第115回近畿血液学地方会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] びまん性大細胞型B細胞性リンパ腫を発症したモルキオ症候群の１例2021
- Author(s)
  藤城綾、雜賀渉、口分田美奈、川畑徳浩、岩佐磨佐紀、西村理恵、河原真大、南口仁志、木藤克之、安藤朗
- Organizer
  第115回近畿血液学地方会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] 潰瘍性大腸炎患者におけるDrug-tolerant assayを用いたベドリズマブ免疫原性の検討2021
- Author(s)
  山下典亮、今井隆行、河原真大、馬場重樹、稲富理、安藤朗
- Organizer
  第12回日本炎症性腸疾患学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] NUDT15遺伝子多型を有するチオプリンによる骨髄抑制は造血幹細胞の障害を引き起こす2020
- Author(s)
  今井隆行、河原真大、辰巳剛一、大野将司、稲富理、角田洋一、安藤朗
- Organizer
  第57回日本消化器免疫学会総会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] 当院で経験した本態性血小板血症合併妊娠の3例2020
- Author(s)
  田代晴加、岩佐磨佐紀、雜賀渉、寺本由加子、永井詩穂、浅井愛、藤城綾、西村理惠、河原真大、南口仁志、木藤克之、安藤朗
- Organizer
  第82回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] 当院で経験したIgD-λ型多発性骨髄腫の4症例2020
- Author(s)
  田代晴加、藤城綾、永井詩穂、浅井愛、岩佐磨佐紀、西村理惠、河原真大、南口仁志、木藤克之、安藤朗
- Organizer
  第117回日本内科学会総会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] Mogamulizumab and radiation therapy in two patients with relapsed mature T-cell neoplasm after related PBSCT.2019
- Author(s)
  Yukako Teramoto, Wataru Saika, Ai Asai, Masaki Iwasa, Aya Fujishiro, Rie Nishimura, Masahiro Kawahara, Hitoshi Minamiguchi, Katsuyuki Kito, Akira Andoh.
- Organizer
  第41回日本造血細胞移植学会総会
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] BCL-2 expression in acute myeloid leukemia and blastic plasmacytoid dendritic cell neoplasm.2019
- Author(s)
  Saika W, Tashiro H, Teramoto Y, Nagai S, Iwasa M, Asai A，Fujishiro A, Nishimura R, Kawahara M, Minamiguchi H, Moritani S, Kito K, Andoh A.
- Organizer
  第81回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] Thiopurine-mediated impairment of hematopoietic stem and progenitor cells in NUDT15R138C knock-in mice and potentiality of Nudt15 genotype-based precision medicine for acute leukemia.2019
- Author(s)
  Goichi Tatsumi, Masahiro Kawahara, Takayuki Imai, Ai Nishishita-Asai, Atushi Nishida, Osamu Inatomi, Akihiko Yokoyama, Yoichi Kakuta, Katsuyuki Kito, and Akira Andoh
- Organizer
  The 24th European hematology association (EHA) congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K08811
[Presentation] Two cases with primary plasma cell leukemia.2018
- Author(s)
  Yukako Teramoto, Masaki Iwasa, Ai Asai, Aya Fujishiro, Rie Nishimura, Masahiro Kawahara, Hitoshi Minamiguchi, Katsuyuki Kito, Akira Ando.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] 急性骨髄性白血病治療の新たな挑戦2018
- Author(s)
  河原真大
- Organizer
  近畿血液地方会
- Invited
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] Aberrant repression of GFI1 super-enhancer by LSD1 plays an important role in leukemia programs in acute myeloid leukemia2017
- Author(s)
  Goichi Tatsumi, Masahiro Kawahara, Akinori Kanai, Hirotaka Matsui, Ryusuke Yamamoto, Masakatsu Hishizawa, Toshiya Inaba, Takayoshi Suzuki, Akira Andoh, and Akifumi Takaori-Kondo
- Organizer
  59th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] sIL-2 receptor is one of the predictive marker of spontaneous regression in MTX-LPD.2017
- Author(s)
  Saika M, Iwasa M, Nagai S, Asai A, Nishimura R, Furuya A, Kawahara M, Minamiguchi H, Kito K, Andoh A
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] 当院における用量調整VRD療法2017
- Author(s)
  Asai A, Nagai S, Usui A, Kumode M, Iwasa M, Nishimura R, Kawahara M, Minamiguchi H, Kito K, Andoh A
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] GFI1 enhancer silenced by LSD1 is important for myeloid differentiation blockage in AML2016
- Author(s)
  Goichi Tatsumi, Masahiro Kawahara, Akinori Kanai, Hirotaka Matsui, Ryusuke Yamamoto, Masakatsu Hishizawa, Toshiya Inaba, Takayoshi Suzuki, Akira Andoh, and Akifumi Takaori-Kondo
- Organizer
  第78回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] Ips Technology Revealed the Genetic and Functional Diversity Present in a Secondary AML Patient2016
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Akira Watanabe, Masahiro Nakamura, Masatoshi Nishizawa, Akifumi Takaori-Kondo, Shinya Yamanaka, and Yoshinori Yoshida,
- Organizer
  The 58th ASH annual meeting and exposition
- Place of Presentation
  San Diego, USA
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] The silence of GFI1 enhancer by LSD1 is associated with myeloid differentiation block in AML2016
- Author(s)
  Goichi Tatsumi, Masahiro Kawahara, Hirotaka Matsui, Masakatsu Hishizawa, Toshiya Inaba, Takayoshi Suzuki, Akira Andoh, and Akifumi Takaori-Kondo
- Organizer
  第75回日本癌学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-06
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] Report of three cases of acute promyelocytic leukemia with CNS relapse2016
- Author(s)
  口分田美奈、臼井　亜沙子、大平　泰之、永井　詩穂、細羽　桜、古屋　彩、瀬川　秀和、河原　真大　南口　仁志、木藤　克之、安藤　朗
- Organizer
  第78回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] A case report of multiple myeloma with central nervous system involvement2016
- Author(s)
  細羽　桜、岩佐　磨佐紀、南口　仁志、口分田美奈、臼井　亜沙子、永井　詩穂、大平　泰之、古屋　彩、瀬川　秀和、河原　真大、木藤　克之、安藤　朗
- Organizer
  第78回日本血液学会
- Place of Presentation
  横浜
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-16K09846
[Presentation] Hypomethylation of the TSDR is a hallmark of the Treg subtype in adult T-cell leukemia2015
- Author(s)
  Yayoi Shimazu, Yutaka Shimazu, Masakatsu Hishizawa, Masahide Hamaguchi, Yuya Nagai, Noriko Sugino, Sumie Fujii, Masahiro Kawahara, Norimitsu Kadowaki, Hiroyoshi Nishikawa, Shimon Sakaguchi, Akifumi Takaori-Kondo
- Organizer
  日本血液学会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] Genetic and cytologic analyses about early T cell precursor acute lymphoblastic leukemia2015
- Author(s)
  Ryusuke Yamamoto, Masahiro Kawahara, Yuya Nagai, Katsuyuki Ohmori, Yayoi Shimazu, Noriko Sugino, Sumie Fujii, Goichi Tatsumi and Akifumi Takaori-Kondo
- Organizer
  日本血液学会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] Generation of engraftable leukemic stem cells from iPS cells derived from a secondary AML patient2015
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Masatoshi Nishizawa, Akifumi Takaori-Kondo, Shinya Yamanaka, and Yoshinori Yoshida
- Organizer
  日本血液学会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] The hierarchy in adult T-cell leukemia that originates from T memory stem cells2015
- Author(s)
  Yuya Nagai, Masahiro Kawahara, Masakatsu Hishizawa, Yayoi Shimazu, Noriko Sugino, Sumie Fujii, Ryusuke Yamamoto, Goichi Tatsumi, Norimitsu Kadowaki, Akifumi Takaori-Kondo
- Organizer
  日本血液学会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] LSD1 regulates myeloid differentiation via affecting the enhancer activity of GFI12015
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Akinori Kanai, Hirotaka Matsui, Goichi Tatsumi, Ryusuke Yamamoto, Yuya Nagai, Sumie Fujii, Yayoi Shimazu, Masakatsu Hishizawa, Toshiya Inaba, Takayoshi Suzuki, and Akifumi Takaori-Kondo
- Organizer
  日本血液学会
- Place of Presentation
  金沢
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] Challenge to identify ATL-initiating cells2013
- Author(s)
  Nagai Y, Kawahara M, Hishizawa M, Sugino N, Shimazu Y, Takaori-Kondo A
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] KDM1A is involved in the myelomonocytic/erythroid differentiation and is a promising target of AML.2013
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Yuya Nagai, Yayoi Shimazu, Masakatsu Hishizawa, and Akifumi Takaori-Kondo.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Challenge to identify ATL-initiating cells.2013
- Author(s)
  Yuya Nagai, Masahiro Kawahara, Masakatsu Hishizawa ,Noriko Sugino, Yayoi Shimazu, and Akifumi Takaori-Kondo.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Inhibition of KDM1A suppresses the growth of acute myeloid leukemia or myelodysplastic syndromes cells through inducing differentiation.2013
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Yuya Nagai, Yayoi Shimazu, Masakatsu Hishizawa, and Akifumi Takaori-Kondo
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Successful allo-SCT following mogamulizumab for a patient with refractory ATL2013
- Author(s)
  Kawata T, Kawase Y, Hishizawa M, Kawahara M, Kondo T, Kitano T, Kadowaki N, Ohmori K, Takaori-Kondo A
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] A Rare Population of Stem Cell Memory T Cells Is an Apex of the Hierarchy of Adult T-Cell Leukemia.2013
- Author(s)
  Yuya Nagai, Masahiro Kawahara, Masakatsu Hishizawa ,Noriko Sugino, Yayoi Shimazu, and Akifumi Takaori-Kondo.
- Organizer
  The 55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] Challenge to identify ATL-initiating cells.2013
- Author(s)
  Yuya Nagai, Masahiro Kawahara, Masakatsu Hishizawa ,Noriko Sugino, Yayoi Shimazu, and Akifumi Takaori-Kondo.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] KDM1A is involved in the myelomonocytic/erythroid differentiation and is a promising target of AML.2013
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Yuya Nagai, Yayoi Shimazu, Masakatsu Hishizawa, and Akifumi Takaori-Kondo.
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] Retrospective analysis of allogeneic HSCT for MDS : A single institution experience2013
- Author(s)
  Kawase Y, Kondo T, Maeda T, Kawahara M, Kitawaki T, Kitano T, Yamashita K, Kawabata H, Takaori-Kondo A
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Inhibition of KDM1A suppresses the growth of acute myeloid leukemia or myelodysplastic syndromes cells through inducing differentiation2013
- Author(s)
  Sugino N, Kawahara M, Suzuki T, Nagai Y, Shimazu Y, Hishizawa M, Takaori-Kondo A
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Retrospective analysis of allogeneic HSCT for MDS:A single institution experience.2013
- Author(s)
  Kawase Y, Kondo T, Maeda T, Kawahara M, Kitawaki T, Kitano T, Yamashita K, Kawabata H, Takaori-Kondo A
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] Inhibition of KDM1A suppresses the growth of acute myeloid leukemia or myelodysplastic syndromes cells through inducing differentiation.2013
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Yuya Nagai, Yayoi Shimazu, Masakatsu Hishizawa, and Akifumi Takaori-Kondo.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] KDM1A is involved in the myelomonocytic/erythroid differentiation and is a promising target of AML2013
- Author(s)
  Sugino N, Kawahara M, Suzuki T, Nagai Y, Shimazu Y, Hishizawa M, Takaori-Kondo A
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] A Rare Population of Stem Cell Memory T Cells Is an Apex of the Hierarchy of Adult T-Cell Leukemia2013
- Author(s)
  Nagai Y, Kawahara M, Hishizawa M, Sugino N, Shimazu Y, Takaori-Kondo A
- Organizer
  The 55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Search for pathogenesis of acquired myelodysplastic syndromes using reprogramming technology.2013
- Author(s)
  Chonabayashi K, Kawahara M, Watanabe A, Okita K, Nishizawa M, Kadowaki N, Takaori-Kondo A, Yamanaka S, Yoshida Y
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] Search for pathogenesis of acquired myelodysplastic syndromes using reprogramming technology2013
- Author(s)
  Chonabayashi K, Kawahara M, Watanabe A, Okita K, Nishizawa M, Kadowaki N, Takaori-Kondo A, Yamanaka S, Yoshida Y
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] A case of blastic plasmacytoid dendritic cell neoplasm with MLL-ENL fusion2013
- Author(s)
  Nakabo Y, Katsurada Y, Kawabata H, Kondo T, Kawahara M, Kitawaki T, Takaori-Kondo A, Yoshida Y
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Clonal and hierarchical expansion of adult T-cell leukemia cells in stem cell memory T-cell subset.2013
- Author(s)
  Yuya Nagai , Masahiro Kawahara , Masakatsu Hishizawa , Noriko Sugino , Yayoi Shimazu , and Akifumi Takaori-Kondo.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] A Rare Population of Stem Cell Memory T Cells Is an Apex of the Hierarchy of Adult T-Cell Leukemia.2013
- Author(s)
  Yuya Nagai, Masahiro Kawahara, Masakatsu Hishizawa ,Noriko Sugino, Yayoi Shimazu, and Akifumi Takaori-Kondo.
- Organizer
  The 55th ASH Annual Meeting and Exposition
- Place of Presentation
  New Orleans, USA
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Clonal and hierarchical expansion of adult T-cell leukemia cells in stem cell memory T-cell subset2013
- Author(s)
  Nagai Y, Kawahara M, Hishizawa M, Sugino N, Shimazu Y, Takaori-Kondo A
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Clonal and hierarchical expansion of adult T-cell leukemia cells in stem cell memory T-cell subset.2013
- Author(s)
  Yuya Nagai , Masahiro Kawahara , Masakatsu Hishizawa , Noriko Sugino , Yayoi Shimazu , and Akifumi Takaori-Kondo.
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] Retrospective analysis of allogeneic SCT for therapy-related MDS/AML : A single center experience2012
- Author(s)
  Fujita H, Kondou T, Sakamoto S, Kawahara M, Yamashita K, Kawabata H, Kadowaki N, Takaori-Kondo A
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-24790971
[Presentation] iPS technology revealed the genetic and functional diversity present in a single MDS patient.
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Keisuke Okita, Masatoshi Nishizawa,Norimitsu Kadowaki, Akifumi Takaori-Kondo, Shinya Yamanaka, and YoshinoriYoshida.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] KDM1A is a promising therapeutic target of myelodysplastic syndromes.
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Sumie Fujii, Yuya Nagai,Yayoi Shimazu, Masakatsu Hishizawa, and Akifumi Takaori-Kondo.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] The Pharmacological Inhibition of KDM1A Displays Preclinical Efficacy in AML/MDS by Inducing Myelomonocytic Differentiation.
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Yuya Nagai, Yayoi Shimazu, Sumie Fujii, Masakatsu Hishizawa,and Akifumi Takaori-Kondo.
- Organizer
  The 56th ASH Annual Meeting andExposition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] iPS technology revealed the genetic and functional diversity present in a single MDS patient.
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Keisuke Okita, Masatoshi Nishizawa,Norimitsu Kadowaki, Akifumi Takaori-Kondo, Shinya Yamanaka, and YoshinoriYoshida.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] The Pharmacological Inhibition of KDM1A Displays Preclinical Efficacy in AML/MDS by Inducing Myelomonocytic Differentiation.
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Yuya Nagai, Yayoi Shimazu, Sumie Fujii, Masakatsu Hishizawa,and Akifumi Takaori-Kondo.
- Organizer
  The 56th ASH Annual Meeting andExposition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PUBLICLY-25118713
[Presentation] KDM1A is a promising therapeutic target of myelodysplastic syndromes.
- Author(s)
  Noriko Sugino, Masahiro Kawahara, Takayoshi Suzuki, Sumie Fujii, Yuya Nagai,Yayoi Shimazu, Masakatsu Hishizawa, and Akifumi Takaori-Kondo.
- Organizer
  第76回日本血液学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] Patient-specific induced pluripotent stem cells recapitulate the maturation defect of myelodysplastic syndromes.
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Keisuke Okita, Masatoshi Nishizawa,Norimitsu Kadowaki, Akifumi Takaori -Kondo, Shinya Yamanaka, and YoshinoriYoshida.
- Organizer
  The 56th ASH Annual Meeting andExposition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PROJECT-26860729
[Presentation] Patient-specific induced pluripotent stem cells recapitulate the maturation defect of myelodysplastic syndromes.
- Author(s)
  Kazuhisa Chonabayashi, Masahiro Kawahara, Keisuke Okita, Masatoshi Nishizawa,Norimitsu Kadowaki, Akifumi Takaori -Kondo, Shinya Yamanaka, and YoshinoriYoshida.
- Organizer
  The 56th ASH Annual Meeting andExposition
- Place of Presentation
  San Francisco, USA
- Year and Date
  2014-12-06 – 2014-12-09
- Data Source
  KAKENHI-PUBLICLY-25118713

1. Tatsumi Goichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
2. Asai Ai

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. BAMBA Shigeki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 安藤朗

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 門脇則光

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
6. 西英一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 松井啓隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KAWAHARA MASAHIRO 河原 真大

KAWAHARA Masahiro 河原 真大

Research Projects

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Alteration of transcription network via super-enhancer in acute leukemiaPrincipal Investigator

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Identification and regulation mechanism of enhancers for hematopoietic cell fate decisionPrincipal Investigator

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Alteration of stress response by a histone methylation abnormality in hematopoietic stem cellsPrincipal Investigator

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ヒストン脱メチル化酵素(KDM)による造血分化制御機構の解明Principal Investigator

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Analysis of leukemogenesis through the NPM fusion genePrincipal Investigator

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[Book] BIO Clinica2012

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[Book] BIO Clinica 多遺伝子疾患, 「急性骨髄性白血病における疾患遺伝子研究」の項2012

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[Journal Article] Thiopurine Use During Pregnancy Has Deleterious Effects on Offspring in Nudt15R138C Knock-In Mice2021

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[Journal Article] Targeted deletion of Atg5 in intestinal epithelial cells promotes dextran sodium sulfate-induced colitis2021

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[Journal Article] Acquired Coagulation Factor V Inhibitor That Was Successfully Treated with Oral Corticosteroid Therapy2021

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[Journal Article] Mucosa-associated gut microbiome in Japanese patients with functional constipation2021

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[Journal Article] Thiopurine pharmacogenomics and pregnancy in inflammatory bowel disease2021

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KAWAHARA MASAHIRO 河原真大

KAWAHARA Masahiro 河原真大