FUKUMURA Kazuhiro 福村和宏

… Alternative Names

FUKUMURA KAZUHIRO 福村和宏

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Researcher Number	80622117
Other IDs
Affiliation (Current)	2025: 藤田医科大学, 腫瘍医学研究センター, 講師
Affiliation (based on the past Project Information) *help	2024: 藤田医科大学, 腫瘍医学研究センター, 講師 2021 – 2023: 藤田医科大学, 医科学研究センター, 講師 2018 – 2020: 藤田医科大学, 総合医科学研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields Except Principal Investigator Basic Section 43010:Molecular biology-related
Keywords	Principal Investigator mRNAスプライシング / 生物進化 / スプライシング / イントロン / ペプチド医薬 / mRNA前駆体スプライシング / SAP30BP / 抗がん剤耐性獲得 / 異常mRNAスプライシング / 抗がん剤耐性 … More / SPF45 / RNAスプライシング / オーロラBキナーゼ / アンチセンスオリゴヌクレオチド / PSAP / アンチセンスヌクレオチド / Pre-mRNAスプライシング / RNPS1 / オーロラB … More Except Principal Investigator SAP30BP / RBM17 (SPF45) / スプライシング / イントロン / mRNA前駆体 Less

The discovery of new essential splicing factors restructure a set of human introns
- Principal Investigator
  
  前田明
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Fujita Health University
生物進化の原動力:イントロンの長大化を支えるスプライシング機構の解明Principal Investigator
- Principal Investigator
  
  福村和宏
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Fujita Health University
Development of mRNA splicing modulators to overcome anticancer drug resistancePrincipal Investigator
- Principal Investigator
  
  Fukumura Kazuhiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fujita Health University
The development of therapeutic antisense oligonucleotide targeted to aurora kinase B as an anti-cancer drugPrincipal Investigator
- Principal Investigator
  
  FUKUMURA KAZUHIRO
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Fujita Health University

All 2023 2022 2021

All Journal Article Presentation

[Journal Article] RBM17 expression Is associated with the efficacy of ICI monotherapy in NSCLC with low PD-L1 expression.2023
- Author(s)
  H. Nagamine, M. Yashiro, N. Yoshimoto, M. Izumi, A. Sugimoto, K. Nakahama, K. Ogawa, Y. Matsumoto, K. Sawa, Y. Tani, H. Kaneda, S. Mitsuoka, K. Yamada, T. Watanabe, K. Aasai, K. Fukumura, A. Mayeda, T. Kawaguchi
- Journal Title
  
  Anticancer Research
  
  Volume: 43 Issue: 10 Pages: 4663-4672
- DOI
  10.21873/anticanres.16662
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Journal Article] SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns2023
- Author(s)
  Fukumura Kazuhiro、Sperotto Luca、Seu? Stefanie、Kang Hyun-Seo、Yoshimoto Rei、Sattler Michael、Mayeda Akila
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 12 Pages: 113534-113534
- DOI
  10.1016/j.celrep.2023.113534
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K05565, KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Journal Article] The mysteries of ‘intron length’ triggered the discovery of novel mechanisms of splicing2022
- Author(s)
  福村和宏、前田明
- Journal Title
  
  生化学
  
  Volume: 94 Issue: 6 Pages: 806-813
- DOI
  10.14952/SEIKAGAKU.2022.940806
- ISSN
  0037-1017
- Year and Date
  2022-12-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-21K07202
[Journal Article] SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns2021
- Author(s)
  Fukumura Kazuhiro、Yoshimoto Rei、Sperotto Luca、Kang Hyun-Seo、Hirose Tetsuro、Inoue Kunio、Sattler Michael、Mayeda Akila
- Journal Title
  
  Nature Communications
  
  Volume: 12 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41467-021-24879-y
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K05563, KAKENHI-PLANNED-21H05276, KAKENHI-PROJECT-20H00448, KAKENHI-PROJECT-21K06018, KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Journal Article] Novel LAMC2 fusion protein has tumor‐promoting properties in ovarian carcinoma2021
- Author(s)
  Daisuke Hoshino、Kato Hisamori、Fukumura Kazuhiro、Mayeda Akila、Miyagi Yohei、Seiki Motoharu、Koshikawa Naohiko
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 12 Pages: 4957-4967
- DOI
  10.1111/cas.15149
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07202, KAKENHI-PROJECT-16H06277, KAKENHI-PLANNED-17H06329, KAKENHI-PROJECT-21K09840
[Journal Article] SPF45/RBM17-dependent splicing implicated in multidrug resistance in cancer chemotherapy.2021
- Author(s)
  K. Fukumura, J.P. Venables, A. Mayeda
- Journal Title
  
  Mol. Cell. Oncol.
  
  Volume: 8 Issue: 6 Pages: 1996318-1996318
- DOI
  10.1080/23723556.2021.1996318
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06024, KAKENHI-PROJECT-21K07202
[Presentation] SAP30BP-RBM17 interaction is an essential process to splice out a subset of human short introns2023
- Author(s)
  福村和宏
- Organizer
  第46回日本分子生物学会年
- Invited
- Data Source
  KAKENHI-PROJECT-21K07202
[Presentation] RNPS1 in PSAP complex controls precise pre-mRNA splicing with periodicity during cell cycle2022
- Author(s)
  Fukumura K., Takeda J., Masuda A., Ohno M. & Mayeda A.
- Organizer
  第 23 回日本 RNA 学会年会(2022)
- Data Source
  KAKENHI-PROJECT-21K07202
[Presentation] RNPS1 in PSAP Complex Controls Pre-mRNA splicing with Periodicity during Cell Cycle2022
- Author(s)
  Fukumura K. & Mayeda A.
- Organizer
  Gordon Research Conference PostTranscriptional Gene Regulation&Integrating (2022)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07202
[Presentation] 新しい分子機構によってスプライシングされるヒトの短いイントロン群2021
- Author(s)
  Kazuhiro Fukumura, Rei Yoshimoto, Tetsuro Hirose, Kunio Inoue , Akila Mayeda
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21K07202

1. 恵美宣彦 (30185144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 前田明 (50212204)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. YOSHIMOTO Rei

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

FUKUMURA Kazuhiro 福村 和宏

FUKUMURA KAZUHIRO 福村 和宏

Research Projects

Research Products

Co-Researchers

The discovery of new essential splicing factors restructure a set of human introns

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

生物進化の原動力:イントロンの長大化を支えるスプライシング機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of mRNA splicing modulators to overcome anticancer drug resistancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The development of therapeutic antisense oligonucleotide targeted to aurora kinase B as an anti-cancer drugPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] RBM17 expression Is associated with the efficacy of ICI monotherapy in NSCLC with low PD-L1 expression.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SAP30BP interacts with RBM17/SPF45 to promote splicing in a subset of human short introns2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The mysteries of ‘intron length’ triggered the discovery of novel mechanisms of splicing2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] SPF45/RBM17-dependent, but not U2AF-dependent, splicing in a distinct subset of human short introns2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel LAMC2 fusion protein has tumor‐promoting properties in ovarian carcinoma2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] SPF45/RBM17-dependent splicing implicated in multidrug resistance in cancer chemotherapy.2021

Author(s)

Journal Title

DOI

Data Source

[Presentation] SAP30BP-RBM17 interaction is an essential process to splice out a subset of human short introns2023

Author(s)

Organizer

Data Source

[Presentation] RNPS1 in PSAP complex controls precise pre-mRNA splicing with periodicity during cell cycle2022

Author(s)

Organizer

Data Source

[Presentation] RNPS1 in PSAP Complex Controls Pre-mRNA splicing with Periodicity during Cell Cycle2022

Author(s)

Organizer

Data Source

[Presentation] 新しい分子機構によってスプライシングされるヒトの短いイントロン群2021

Author(s)

Organizer

Data Source

FUKUMURA Kazuhiro 福村和宏

FUKUMURA KAZUHIRO 福村和宏