Watanabe Hitomi 渡邊仁美

Researcher Number	80624056
Other IDs
Affiliation (Current)	2025: 京都大学, 医生物学研究所, 助教
Affiliation (based on the past Project Information) *help	2021 – 2022: 京都大学, 医生物学研究所, 助教 2019 – 2020: 京都大学, ウイルス・再生医科学研究所, 助教 2016 – 2017: 京都大学, ウイルス・再生医科学研究所, 助教 2015: 京都大学, 再生医科学研究所, その他
Review Section/Research Field	Principal Investigator Basic Section 42030:Animal life science-related / Obstetrics and gynecology Except Principal Investigator Basic Section 42040:Laboratory animal science-related
Keywords	Principal Investigator 精子 / 精子運動性解析 / マウス精子 / 妊娠制御 / 精子機能 / GPIアンカー型タンパク質 / マウス / 体外受精 / 精子表面タンパク質 / 受精 … More / 精子成熟化シグナル / 受精メカニズム / Lcn2 / 生殖ホルモン / 免疫細胞 / Ｌｃｎ２ / 卵巣由来分泌因子 / 卵巣腫瘍 / インヒビン / RAG2依存性免疫細胞 / 子宮粘膜 / 精子活性化 / 性ホルモン制御 / 常在細菌叢 / 免疫担当細胞 / Lipocalin2 … More Except Principal Investigator 遺伝子組み換え / ヒト免疫系の再構築 / HLA遺伝子座 / マウス ES細胞 / HLA / HLA(MHC) / マウスES細胞 / ヒト化マウス / 細胞融合 Less

Male regulation of pregnancy revealed by a novel GPI-anchored proteinPrincipal Investigator
- Principal Investigator
  
  Watanabe Hitomi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 42030:Animal life science-related
- Research Institution
  Kyoto University
Reconstruction of human immune system in mice
- Principal Investigator
  
  Takeda Junji
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42040:Laboratory animal science-related
- Research Institution
  Osaka University
Sperm maturation induced by immunocompetent cells and symbiotic bacteriaPrincipal Investigator
- Principal Investigator
  
  Watanabe Hitomi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  Kyoto University

All 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes.2018
- Author(s)
  Shukunami C, Takimoto A, Nishizaki Y, Yoshimoto Y, Tanaka S, Miura S, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y.
- Journal Title
  
  Scientific reports
  
  Volume: 8 Issue: 1 Pages: 1-12
- DOI
  10.1038/s41598-018-21194-3
- NAID
  120006522882
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17092, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K18478, KAKENHI-PROJECT-18J40203
[Journal Article] Stem cell nich-specific Ebf3 maintains the bone marrow cavity.2018
- Author(s)
  Seike, M., Omatsu, Y., Watanabe, H., Kondoh, G., Nagasawa, T.
- Journal Title
  
  Genes ＆ Development
  
  Volume: 32 Issue: 5-6 Pages: 359-372
- DOI
  10.1101/gad.311068.117
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-17H05643, KAKENHI-PROJECT-16H06232, KAKENHI-PROJECT-15K21098
[Journal Article] PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.2018
- Author(s)
  M Morita, T Sato, M Nomura, Y Sakamoto, Y Inoue, R Tanaka, S Ito, K Kurosawa, K Yamaguchi, Y Sugiura, H Takizaki, Y Yamashita, R Katakura, I Sato, Y Okada, H Watanabe, G Kondoh, et al.
- Journal Title
  
  Cancer Cell
  
  Volume: 12 Issue: 3 Pages: 355-367
- DOI
  10.1016/j.ccell.2018.02.004
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07296, KAKENHI-PROJECT-16K09597, KAKENHI-PROJECT-16K10486, KAKENHI-PROJECT-17K19620, KAKENHI-PROJECT-17K16876, KAKENHI-PLANNED-25111006, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-15K09237, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19745, KAKENHI-PROJECT-17K07187, KAKENHI-PUBLICLY-17H05534, KAKENHI-PUBLICLY-17H06011, KAKENHI-PROJECT-16K10774, KAKENHI-PROJECT-17K19606, KAKENHI-PLANNED-17H06301, KAKENHI-PROJECT-16K07187, KAKENHI-PROJECT-17K07231
[Journal Article] Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment.2018
- Author(s)
  Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, Kuchimaru T, Sakamoto T, Watanabe H, Kondoh G, Shinae Kizaka-Kondoh.
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 13 Pages: 11209-11226
- DOI
  10.18632/oncotarget.24359
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06829, KAKENHI-PROJECT-15J02021, KAKENHI-PROJECT-15K21098
[Journal Article] Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.2017
- Author(s)
  Nandita Rani Das, Hironori Miyata, Hideyuki Hara, Keiji Uchiyama, Junji Chida, Masashi Yano, Hitomi Watanabe, Gen Kondoh, Suehiro Sakaguchi
- Journal Title
  
  Archives of Virology
  
  Volume: 印刷中 Issue: 7 Pages: 1867-1876
- DOI
  10.1007/s00705-017-3295-3
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01560, KAKENHI-PROJECT-26293212, KAKENHI-PROJECT-15K15380, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K10029, KAKENHI-PROJECT-17K08859
[Journal Article] Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors2017
- Author(s)
  Ohashi Munehiro、Umemura Yasuhiro、Koike Nobuya、Tsuchiya Yoshiki、Inada Yutaka、Watanabe Hitomi、Tanaka Tomoko、Minami Yoichi、Ukimura Osamu、Miki Tsuneharu、Tajiri Tatsuro、Kondoh Gen、Yamada Yasuhiro、Yagita Kazuhiro
- Journal Title
  
  Genes to Cells
  
  Volume: 23 Issue: 2 Pages: 60-69
- DOI
  10.1111/gtc.12552
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-16K19008, KAKENHI-PROJECT-16H01880, KAKENHI-PROJECT-15H04683
[Journal Article] Prion Protein Devoid of the Octapeptide Repeat Region Delays Bovine Spongiform Encephalopathy Pathogenesis in Mice.2017
- Author(s)
  Hara H, Miyata H, Das NR, Chida J, Yoshimochi T, Uchiyama K, Watanabe H, Kondoh G, Yokoyama T, Sakaguchi S
- Journal Title
  
  Journal of Virology
  
  Volume: - Issue: 1
- DOI
  10.1128/jvi.01368-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K10029, KAKENHI-PUBLICLY-17H05701, KAKENHI-PROJECT-15K21098, KAKENHI-PUBLICLY-17H05702
[Journal Article] Lipid raft dynamics linked to sperm competency for fertilization in mice.2017
- Author(s)
  Watanabe, H., R. Takeda, K. Hirota, G. Kondoh.
- Journal Title
  
  Genes to Cells
  
  Volume: 印刷中 Issue: 5 Pages: 493-500
- DOI
  10.1111/gtc.12491
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K21098
[Journal Article] Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system.2017
- Author(s)
  Yoshimoto Y, Takimoto A, Watanabe H, Hiraki Y, Kondoh G, Shukunami C.
- Journal Title
  
  Sci Rep
  
  Volume: 7 Issue: 1 Pages: 45010-45010
- DOI
  10.1038/srep45010
- NAID
  120005998026
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293395, KAKENHI-PROJECT-15K21098
[Journal Article] PARI regulates stalled replication fork proessing to maintain genome stability upon replication stress in mice2017
- Author(s)
  Ayako L. Mochizuki, Ami Katanaya, Eri Hayashi, Mihoko Hosokawa, Emiko Moribe, Akira Motegi, Masamichi Ishiai,Minoru Takata, Gen Kondoh, Hitomi Watanabe, Norio Nakatsuji, and Shinichiro Chuma
- Journal Title
  
  Mol. Cell. Biol
  
  Volume: 37 (23) Issue: 23
- DOI
  10.1128/mcb.00117-17
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K00548, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25112004, KAKENHI-PROJECT-15H01738, KAKENHI-PROJECT-15K21098
[Journal Article] Disruption of MeCP2 attenuates circadian rhythm in CRISPR/Cas9-based Rett syndrome model mouse.2015
- Author(s)
  Tsuchiya Y., Minami Y., Umemura Y., Watanabe H., Ono D., Nakamura W., Takahashi T., Honma S., Kondoh G., Matsuishi T. & Yagita K.
- Journal Title
  
  Genes to Cells
  
  Volume: 20 Issue: 12 Pages: 992-1005
- DOI
  10.1111/gtc.12305
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K08212, KAKENHI-PROJECT-15K09608, KAKENHI-PROJECT-26462809, KAKENHI-PROJECT-15K21098, KAKENHI-PROJECT-26860156, KAKENHI-PLANNED-24119004, KAKENHI-PROJECT-25250012, KAKENHI-PROJECT-15H04683, KAKENHI-PROJECT-25461568
[Presentation] Lipid raft dynamics linked to sperm competency for fertilization in mice2017
- Author(s)
  Gen Kondoh, Hitomi Watanabe, Rie Takeda and Keiji Hirota
- Organizer
  第4回国際生殖生物学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21098
[Presentation] マウス精子成熟における遺伝的背景の影響について2016
- Author(s)
  渡邊　仁美、竹田　理恵、廣田　圭司、近藤　玄
- Organizer
  第63回日本実験動物学会総会
- Place of Presentation
  川崎市
- Year and Date
  2016-05-05
- Data Source
  KAKENHI-PROJECT-15K21098
[Presentation] Development and characterization of monoclonal antibodies against a stable sperm surface antigen.2016
- Author(s)
  Hitomi Watanabe, Takatoku Oida, Gen Kondoh and Keiji Hirota
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  那覇市
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K21098
[Presentation] マウス精子成熟における遺伝的背景の影響について2016
- Author(s)
  渡邊　仁美
- Organizer
  京都大学再生医科学研究所　若手発表会
- Place of Presentation
  京都
- Year and Date
  2016-01-21
- Data Source
  KAKENHI-PROJECT-15K21098

1. Takeda Junji (50163407)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 近藤玄 (40243258)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YOSHIMOTO Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. Shukunami Chisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. CHIDA Junji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. HARA Hideuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. SAKAMOTO Takeharu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. MOTEGI Akira

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 坂口末廣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 長澤丘司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渡辺利雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 八木田和弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 土谷佳樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 滝本晶

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Hitomi 渡邊 仁美

Research Projects

Research Products

Co-Researchers

Male regulation of pregnancy revealed by a novel GPI-anchored proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Reconstruction of human immune system in mice

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Sperm maturation induced by immunocompetent cells and symbiotic bacteriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes.2018

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Stem cell nich-specific Ebf3 maintains the bone marrow cavity.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PKM1 Confers Metabolic Advantages and Promotes Cell-Autonomous Tumor Cell Growth.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of prion protein devoid of the N-terminal residues 25-50 on prion pathogenesis in mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Disruption of circadian clockwork in in vivo reprogramming-induced mouse kidney tumors2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prion Protein Devoid of the Octapeptide Repeat Region Delays Bovine Spongiform Encephalopathy Pathogenesis in Mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Lipid raft dynamics linked to sperm competency for fertilization in mice.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] PARI regulates stalled replication fork proessing to maintain genome stability upon replication stress in mice2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Disruption of MeCP2 attenuates circadian rhythm in CRISPR/Cas9-based Rett syndrome model mouse.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] Lipid raft dynamics linked to sperm competency for fertilization in mice2017

Watanabe Hitomi 渡邊仁美