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TSUGE MITSURU  津下 充

… Alternative Names

TSUGE Mitsuru  津下 充

津下 充  ツゲ ミツル

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Researcher Number 80625004
Other IDs
  • ORCIDhttps://orcid.org/0000-0001-9010-4708
Affiliation (Current) 2025: 岡山大学, 医歯薬学域, 准教授
Affiliation (based on the past Project Information) *help 2023: 岡山大学, 医歯薬学域, 准教授
2021 – 2022: 岡山大学, 医歯薬学域, 講師
2019 – 2020: 岡山大学, 医歯薬学総合研究科, 講師
2014: 松山赤十字病院, 小児科
2012: 岡山大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics
Except Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Infectious disease medicine
Keywords
Principal Investigator
マクロファージ / 血管透過性 / 自然免疫 / インフルエンザ脳症 / 脳血管内皮細胞 / IL-6 / トール様受容体 / インターロイキン1受容体 / 血液脳関門 / 末梢血単核球 … More / 血管内皮細胞 / COX-2 / ストレスファイバー / VEカドヘリン / HMGB-1 / 炎症性サイトカイン / 腫瘍壊死因子-α / タイトジャンクション / サイトカイン / 脳浮腫 / カイニン酸 / アセトアミノフェン / テオフィリン / ジクロフェナクナトリウム / 痙攣重積型インフルエンザ脳症 … More
Except Principal Investigator
血管内皮障害 / 後遺症 / COVID-19 / 生体マーカー / ワクチン / 病態生理 / 小児 / 感染症 / 川崎病 / アミノ酸代謝 / 一酸化窒素 / 酸化ストレス / 後遺障害 / 合併症 / ウイルス感染症 / 新型コロナウイルス / H1N1pdm / 喘息 / ARDS / AH7N9 / 脳症 / H5N1 / チオレドキシン / HMGB-1 / 肺炎 / インフルエンザ Less
  • Research Projects

    (5 results)
  • Research Products

    (24 results)
  • Co-Researchers

    (7 People)
  •  Elucidation of pathogenesis and preventive measures for complications in pediatric COVID-19

    • Principal Investigator
      塚原 宏一
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Okayama University
  •  IL-1受容体・トール様受容体シグナルを制御するインフルエンザ脳症の新規治療探索Principal Investigator

    • Principal Investigator
      津下 充
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Okayama University
  •  Search for new treatments for influenza associated encephalopathy targeting innate immune mediatorsPrincipal Investigator

    • Principal Investigator
      TSUGE MITSURU
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      Okayama University
  •  Study of the therapeutic agent for the treatment of highly pathogenic influenza

    • Principal Investigator
      MORISHIMA Tsuneo
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Infectious disease medicine
    • Research Institution
      Okayama University
  •  痙攣重積型インフルエンザ脳症の病態解析と新規治療薬の検索Principal Investigator

    • Principal Investigator
      津下 充
    • Project Period (FY)
      2012
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      Okayama University

All 2023 2022 2021 2020 2019 2014 2013

All Journal Article Presentation Book

  • [Book] Influenza: Advances in Diagnosis and Management2020

    • Author(s)
      Tsuge M, Yashiro M, Ohno N, Tsukahara H, Fujita J
    • Total Pages
      229
    • Publisher
      Springer Nature
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Journal Article] Impacts of routine varicella vaccination program and COVID-19 pandemic on varicella and herpes zoster incidence and health resource use among children in Japan2023

    • Author(s)
      Uda K, Okubo Y, Tsuge M, Tsukahara H, Miyairi I
    • Journal Title

      Vaccine

      Volume: 41(34) Issue: 34 Pages: 4958-4966

    • DOI

      10.1016/j.vaccine.2023.06.054

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07820, KAKENHI-PROJECT-22K07935
  • [Journal Article] Need for re-evaluating the risk of coronavirus disease 2019 transmission to neonates2023

    • Author(s)
      Uda K, Tsuge M, Yashiro M, Honda T, Tsukahara H
    • Journal Title

      Pediatr Int

      Volume: 65(1) Issue: 1

    • DOI

      10.1111/ped.15460

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07820, KAKENHI-PROJECT-22K07935, KAKENHI-PROJECT-21H02738
  • [Journal Article] Roles of Oxidative Injury and Nitric Oxide System Derangements in Kawasaki Disease Pathogenesis: A Systematic Review2023

    • Author(s)
      Tsuge M, Uda K, Eitoku T, Matsumoto N, Yorifuji T, Tsukahara H
    • Journal Title

      Int J Mol Sci

      Volume: 24(20) Issue: 20 Pages: 15450-15450

    • DOI

      10.3390/ijms242015450

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07820, KAKENHI-PROJECT-22K07935
  • [Journal Article] Successful use of dupilumab for egg-induced eosinophilic gastroenteritis with duodenal ulcer: a pediatric case report and review of literature2023

    • Author(s)
      Tsuge Mitsuru、Shigehara Kenji、Uda Kazuhiro、Kawano Seiji、Iwamuro Masaya、Saito Yukie、Yashiro Masato、Ikeda Masanori、Tsukahara Hirokazu
    • Journal Title

      Allergy, Asthma & Clinical Immunology

      Volume: 19 Issue: 1 Pages: 103-103

    • DOI

      10.1186/s13223-023-00859-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07935
  • [Journal Article] Evaluation of the association of birth order and group childcare attendance with Kawasaki disease using data from a nationwide longitudinal survey2023

    • Author(s)
      Namba T, Takeuchi A, Matsumoto N, Tsuge M, Yashiro M, Tsukahara H, Yorifuji T
    • Journal Title

      Front Pediatr

      Volume: 11 Pages: 1127053-1127053

    • DOI

      10.3389/fped.2023.1127053

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07820, KAKENHI-PROJECT-22K07935, KAKENHI-PROJECT-20K10498
  • [Journal Article] Decreased Levels of Histidine-Rich Glycoprotein and Increased Levels of High-Mobility Group Box 1 are Risk Factors for Refractory Kawasaki Disease2022

    • Author(s)
      Namba T, Yashiro M, Fujii Y, Tsuge M, Liu K, Nishibori M, Tsukahara H
    • Journal Title

      Mod Rheumatol

      Volume: - Issue: 3 Pages: 599-607

    • DOI

      10.1093/mr/roac040

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K07822, KAKENHI-PROJECT-22K07935, KAKENHI-PROJECT-22K07820
  • [Journal Article] 新生児領域における酸化ストレス制御の意義2022

    • Author(s)
      塚原宏一、宮原宏幸、鷲尾洋介、津下充、馬場健児
    • Journal Title

      日本小児高血圧研究会誌

      Volume: 18 Pages: 10-18

    • Data Source
      KAKENHI-PROJECT-22K07820
  • [Journal Article] Correlation between national surveillance and search engine query data on respiratory syncytial virus infections in Japan2022

    • Author(s)
      Uda K, Hagiya H, Yorifuji T, Koyama T, Tsuge M, Yashiro M, Tsukahara H
    • Journal Title

      BMC Public Health

      Volume: 22 Issue: 1 Pages: 1517-1517

    • DOI

      10.1186/s12889-022-13899-y

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07820, KAKENHI-PROJECT-22K07935, KAKENHI-PROJECT-22K10415
  • [Journal Article] Novel Lung Growth Strategy with Biological Therapy Targeting Airway Remodeling in Childhood Bronchial Asthma2022

    • Author(s)
      Tsuge M, Ikeda M, Tsukahara H
    • Journal Title

      Children (Basel)

      Volume: 9 Issue: 8 Pages: 1253-1253

    • DOI

      10.3390/children9081253

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07820, KAKENHI-PROJECT-22K07935
  • [Journal Article] Severe pediatric asthma with a poor response to omalizumab: a report of three cases and three-dimensional bronchial wall analysis2022

    • Author(s)
      Tsuge Mitsuru、Ikeda Masanori、Kondo Yoichi、Tsukahara Hirokazu
    • Journal Title

      Journal of International Medical Research

      Volume: 50 Issue: 1 Pages: 1-10

    • DOI

      10.1177/03000605211070492

    • NAID

      120007183226

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Journal Article] Neonatal hemochromatosis with εγδβ-thalassemia: a case report and analysis of serum iron regulators2022

    • Author(s)
      Tsuge Mitsuru、Kodera Aya、Sumitomo Hiromi、Araki Tooru、Yoshida Ryuichi、Yasui Kazuya、Sato Hiroki、Washio Yosuke、Washio Kana、Shigehara Kenji、Yashiro Masato、Yagi Takahito、Tsukahara Hirokazu
    • Journal Title

      BMC Pediatrics

      Volume: 22 Issue: 1

    • DOI

      10.1186/s12887-022-03706-3

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K07935
  • [Journal Article] Anaphylaxis after jellyfish ingestion with no history of stings: a pediatric case report2021

    • Author(s)
      Tsuge Mitsuru、Ikeda Masanori、Mitani Osamu、Yasui Masato、Tsukahara Hirokazu
    • Journal Title

      Allergy, Asthma & Clinical Immunology

      Volume: 17 Issue: 1 Pages: 99-99

    • DOI

      10.1186/s13223-021-00601-x

    • NAID

      120007161118

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Journal Article] COVID-19 in Okayama Prefecture: Looking back and looking forward2021

    • Author(s)
      Tsukahara Hirokazu、Higashionna Tsukasa、Tsuge Mitsuru、Miyamura Junko、Kusano Nobuchika
    • Journal Title

      Global Health & Medicine

      Volume: 3 Issue: 2 Pages: 102-106

    • DOI

      10.35772/ghm.2020.01104

    • NAID

      130008036363

    • ISSN
      2434-9186, 2434-9194
    • Year and Date
      2021-04-30
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Journal Article] Reactive Oxygen Species and Antioxidative Defense in Chronic Obstructive Pulmonary Disease2021

    • Author(s)
      Taniguchi A, Tsuge M, Miyahara N, Tsukahara H
    • Journal Title

      Antioxidants (Basel)

      Volume: 28;10(10) Issue: 10 Pages: 1537-1537

    • DOI

      10.3390/antiox10101537

    • NAID

      120007170512

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08277, KAKENHI-PROJECT-19K08278
  • [Journal Article] Terry’s nails in an infant with liver cirrhosis2021

    • Author(s)
      Uda Kazuhiro、Tsuge Mitsuru、Shigehara Kenji、Yashiro Masato、Tsukahara Hirokazu
    • Journal Title

      Archives of Disease in Childhood

      Volume: 107 Issue: 5 Pages: 485-485

    • DOI

      10.1136/archdischild-2021-322953

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Journal Article] Anti-high mobility group box 1 monoclonal antibody suppressed hyper-permeability and cytokine production in human pulmonary endothelial cells infected with influenza A virus2021

    • Author(s)
      Namba T, Tsuge M, Yashiro M, Saito Y, Liu K, Nishibori M, Morishima T, Tsukahara H
    • Journal Title

      Inflamm Res

      Volume: 70(10-12) Issue: 10-12 Pages: 1101-1111

    • DOI

      10.1007/s00011-021-01496-5

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08277, KAKENHI-PROJECT-19K08278, KAKENHI-PROJECT-19H03408
  • [Journal Article] Current Insights into Atopic March2021

    • Author(s)
      Tsuge M, Ikeda M, Matsumoto N, Yorifuji T, Tsukahara H
    • Journal Title

      Children (Basel)

      Volume: 19;8(11) Issue: 11 Pages: 1067-1067

    • DOI

      10.3390/children8111067

    • NAID

      120007180266

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08277, KAKENHI-PROJECT-19K08278
  • [Journal Article] Gene expression analysis in children with complex seizures due to influenza A(H1N1)pdm09 or rotavirus gastroenteritis,2014

    • Author(s)
      Tsuge M1, Oka T, Yamashita N, Saito Y, Fujii Y, Nagaoka Y, Yashiro M, Tsukahara H, Morishima T.
    • Journal Title

      J Neurovirol.

      Volume: 20 Issue: 1 Pages: 73-84

    • DOI

      10.1007/s13365-013-0231-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25460437, KAKENHI-PROJECT-25461594, KAKENHI-PROJECT-25670465
  • [Journal Article] Pathogenic mechanisms of influenza A(H1N1)pdm09 infection elucidated on gene expression profiling.2013

    • Author(s)
      Yamashita N, Tsukahara H, Tsuge M, Nagaoka Y, Yashiro M, Saito Y, Fujii Y, Oka T, Morishima T.
    • Journal Title

      Pediatr Int.

      Volume: 55 Pages: 572-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670465
  • [Presentation] インフルエンザA(H1N1)pdm09による急性呼吸窮迫症候群に対して体外式膜型人工肺とペラミビル・バロキサビルマルボキシル併用療法で改善した一例2020

    • Author(s)
      津下 充, 茂原 研司, 斎藤 有希惠, 八代 将登, 塚原 宏一
    • Organizer
      第52回日本小児感染症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Presentation] 肺血管内皮細胞を用いた重症インフルエンザ肺炎モデルの構築と high mobility group box 1抗体による肺血管透過性亢進の抑制効果2020

    • Author(s)
      難波貴弘, 津下充, 八代将登, 塚原宏一, 森島恒雄
    • Organizer
      第61回日本臨床ウイルス学会
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Presentation] ヒト脳血管内皮細胞を用いた高サイトカイン血症モデルにおけるhigh mobility group box-1抗体の血管透過性抑制効果2019

    • Author(s)
      津下 充,難波貴弘,西堀正洋,斎藤有希恵,八代将登,塚原宏一,森島恒雄
    • Organizer
      第51回日本小児感染症学会総会・学術集会
    • Data Source
      KAKENHI-PROJECT-19K08278
  • [Presentation] 痙攣重責を示したインフルエンザA(H1N1)pdm及びロタウイルス胃腸炎の宿主遺伝子発現の解析2014

    • Author(s)
      津下 充
    • Organizer
      第46回日本小児感染症学会
    • Place of Presentation
      東京 京王プラザホテル
    • Year and Date
      2014-10-19
    • Data Source
      KAKENHI-PROJECT-25670465
  • 1.  塚原 宏一 (90207340)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 2.  MORISHIMA Tsuneo (90157892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  FUJI Yousuke (80549775)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  OKA Takashi
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 5.  西堀 正洋
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  宮原 宏幸
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  伊藤 佐智夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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