okamoto toru 岡本徹

… Alternative Names

TORU OKAMOTO 岡本徹

Okamoto Toru 岡本徹

OKAMOTO Toru 岡本徹

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Researcher Number	80628595
Other IDs	https://orcid.org/0000-0003-4000-3102
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 教授
Affiliation (based on the past Project Information) *help	2025: 順天堂大学, 大学院医学研究科, 教授 2023: 順天堂大学, 大学院医学研究科, 教授 2020 – 2023: 大阪大学, 高等共創研究院, 教授 2017: 大阪大学, 微生物病研究所, 准教授 2016: 大阪大学, 微生物病研究所, 助教 2015: 大阪大学, 微生物病研究所分子ウイルス分野, 助教 2012 – 2013: 大阪大学, 微生物病研究所, 助教
Review Section/Research Field	Principal Investigator Virology / Basic Section 49060:Virology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Virology / Transformative Research Areas, Section (III)
Keywords	Principal Investigator 細胞死 / ウイルス学 / フラビウイルス / アポトーシス / 細胞核 / 代謝フラックス / エネルギー代謝 / 蛋白質翻訳 / 翻訳 / 解糖系 … More / ワクチン / ATP / デングウイルス / 日本脳炎ウイルス / 貪食 / BCL2 / Bcl-2 / ウイルス … More Except Principal Investigator 抗菌作用 / 脂肪性肝炎 / 腸内細菌 / 胆汁酸 / ウイルス粒子形成 / ウイルス複製 / エボラウイルス / 膜界面分子協奏 / 免疫 / 肝がん / 肝硬変 / 免疫低下 / NK細胞 / 肝癌 / 肝臓癌 / ナチュラルキラー細胞 / HCV / SPP / 治療 / イメージング / 遺伝子治療 / 癌 / レオウイルス Less

膜界面生物学に基づくエボラウイルス複製の分子基盤
- Principal Investigator
  
  南保明日香
- Project Period (FY)
  2025 – 2029
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Nagasaki University
Investigating MASH treatment strategies that emphasize the physiological roles of fatty acid-linked bile acids in the intestinal tract
- Principal Investigator
  
  鈴木光幸
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Juntendo University
Immunoregulatory mechanisms in patients with LC-HCC
- Principal Investigator
  
  Sachiyo Yoshio
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  National Center for Global Health and Medicine
Elucidation of protein translation shutoff by mosquito-borne flavivirusPrincipal Investigator
- Principal Investigator
  
  TORU OKAMOTO
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Juntendo University
  Osaka University
Infection with flaviviruses requires BCLXL for cell survivalPrincipal Investigator
- Principal Investigator
  
  TORU OKAMOTO
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Characterization of SPP involved in pathogenesis of HCV
- Principal Investigator
  
  Matsuura Yoshiharu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Development of replication-selective oncolytic viral vector using modified mammalian orthoreovirus
- Principal Investigator
  
  KANAI YUTA
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Virology
- Research Institution
  Osaka University
Regulation of Bcl-2 protein family prtoteins by virus infectionPrincipal Investigator
- Principal Investigator
  
  OKAMOTO Toru
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Virology
- Research Institution
  Osaka University

All 2024 2022 2021 2020 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation

[Journal Article] Immunoglobulin-like transcript 2 as an impaired anti-tumor cytotoxicity marker of natural killer cells in patients with hepatocellular carcinoma2024
- Author(s)
  Sakata Toshihiro、Yoshio Sachiyo、Yamazoe Taiji、Mori Taizo、Kakazu Eiji、Aoki Yoshihiko、Aoyanagi Nobuyoshi、Okamoto Toru、Ito Takanori、Toyoda Hidenori、Kawaguchi Takumi、Ono Yoshihiro、Takahashi Yu、Taketomi Akinobu、Kanto Tatsuya
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 15 Pages: 1389411-1389411
- DOI
  10.3389/fimmu.2024.1389411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K08020
[Journal Article] SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication2022
- Author(s)
  Miyamoto Yoichi、Itoh Yumi、Suzuki Tatsuya、Tanaka Tomohisa、Sakai Yusuke、Koido Masaru、Hata Chiaki、Wang Cai-Xia、Otani Mayumi、Moriishi Kohji、Tachibana Taro、Kamatani Yoichiro、Yoneda Yoshihiro、Okamoto Toru、Oka Masahiro
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 483-483
- DOI
  10.1038/s42003-022-03427-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03444, KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-20K06455
[Journal Article] Establishment of monoclonal antibodies broadly neutralize infection of hepatitis B virus.2022
- Author(s)
  Zhang H, Itoh Y, Suzuki T, Ihara KI, Tanaka T, Haga S, Enatsu H, Yumiya M, Kimura M, Takada A, Itoh D, Shibazaki Y, Nakao S, Yoshio S, Miyakawa K, Miyamoto Y, Sasaki H, Kajita T, Sugiyama M, Mizokami M, Tachibana T, Ryo A, Moriishi K, Miyoshi E, Kanto T, Okamoto T, Matsuura Y.
- Journal Title
  
  Microbiol Immunol.
  
  Volume: 66(4) Issue: 4 Pages: 179-192
- DOI
  10.1111/1348-0421.12964
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-23K24228
[Journal Article] Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 12021
- Author(s)
  Nakae Aya、Kodama Michiko、Okamoto Toru、Tokunaga Makoto、Shimura Hiroko、Hashimoto Kae、Sawada Kenjiro、Kodama Takahiro、Copeland Neal G.、Jenkins Nancy A.、Kimura Tadashi
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 552 Pages: 120-127
- DOI
  10.1016/j.bbrc.2021.03.049
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-20K22978, KAKENHI-PROJECT-19H03799
[Journal Article] Hepatitis C virus modulates signal peptide peptidase to alter host protein processing.2021
- Author(s)
  11.Hirano J, Yoshio S, Sakai Y, Songling L, Suzuki T, Itoh Y, Zhang H, Chen DV, Haga S, Oomori H, Kodama T, Maeda Y, Ono Y, Takahashi Y, Standley DM, Yamamoto M, Moriishi K, Moriya K, Kanto T, Takehara T, Koike K, Matsuura Y, Okamoto T.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 118(22) Issue: 22 Pages: 2026184118-2026184118
- DOI
  10.1073/pnas.2026184118
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03479, KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-20H03661, KAKENHI-PROJECT-21K08020
[Journal Article] Phenotypic Characterization by Single-Cell Mass Cytometry of Human Intrahepatic and Peripheral NK Cells in Patients with Hepatocellular Carcinoma2021
- Author(s)
  Yoshida Yuichi、Yoshio Sachiyo、Yamazoe Taiji、Mori Taizo、Tsustui Yuriko、Kawai Hironari、Yoshikawa Shiori、Fukuhara Takasuke、Okamoto Toru、Ono Yoshihiro、Takahashi Yu、Hashida Ryuki、Kawaguchi Takumi、Taketomi Akinobu、Kanto Tatsuya
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 6 Pages: 1495-1495
- DOI
  10.3390/cells10061495
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K08020, KAKENHI-PROJECT-20K17038
[Journal Article] Ponesimod suppresses hepatitis B virus infection by inhibiting endosome maturation2021
- Author(s)
  Fauzyah Yuzy、Ono Chikako、Torii Shiho、Anzai Itsuki、Suzuki Rigel、Izumi Takuma、Morioka Yuhei、Maeda Yusuke、Okamoto Toru、Fukuhara Takasuke、Matsuura Yoshiharu
- Journal Title
  
  Antiviral Research
  
  Volume: 186 Pages: 104999-104999
- DOI
  10.1016/j.antiviral.2020.104999
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-20K22951, KAKENHI-PROJECT-21K15042
[Journal Article] Deneddylation by SENP8 restricts hepatitis B virus propagation2021
- Author(s)
  Chen David Virya、Suzuki Tatsuya、Itoh Yumi、Maeda Yusuke、Hirano Junki、Haga Saori、Zhang He、Ito Daiki、Matsuura Yoshiharu、Okamoto Toru
- Journal Title
  
  Microbiology and Immunology
  
  Volume: 65 Issue: 3 Pages: 125-135
- DOI
  10.1111/1348-0421.12874
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-19J12369
[Journal Article] MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex2020
- Author(s)
  Djajawi Tirta Mario、Liu Lei、Gong Jia-nan、Huang Allan Shuai、Luo Ming-jie、Xu Zhen、Okamoto Toru、Call Melissa J.、Huang David C. S.、van Delft Mark F.
- Journal Title
  
  Cell Death & Differentiation
  
  Volume: 27 Issue: 8 Pages: 2484-2499
- DOI
  10.1038/s41418-020-0517-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03495
[Journal Article] Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis2020
- Author(s)
  Fukushima Kiyoharu、Satoh Takashi、Sugihara Fuminori、Sato Yuki、Okamoto Toru、Mitsui Yuichi、Yoshio Sachiyo、Li Songling、Nojima Satoshi、Motooka Daisuke、Nakamura Shota、Kida Hiroshi、Standley Daron M.、Morii Eiichi、Kanto Tatsuya、Yanagita Motoko、Matsuura Yoshiharu、Nagasawa Takashi、Kumanogoh Atsushi、Akira Shizuo
- Journal Title
  
  Immunity
  
  Volume: 52 Issue: 3 Pages: 542-556
- DOI
  10.1016/j.immuni.2020.02.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16557, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-ORGANIZER-16H06429, KAKENHI-PUBLICLY-18H05032, KAKENHI-PROJECT-18H03998, KAKENHI-PROJECT-18H02430, KAKENHI-PROJECT-16K09537, KAKENHI-PROJECT-17K19557, KAKENHI-PROJECT-17K16081, KAKENHI-PROJECT-15H05704, KAKENHI-PROJECT-20H03495, KAKENHI-PROJECT-20H03697, KAKENHI-PROJECT-19K22620
[Journal Article] Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag.2018
- Author(s)
  Tamura T, Fukuhara T, Uchida T, Ono C, Mori H, Sato A, Fauzyah Y, Okamoto T, Kurosu T, Setoh YX, Imamura M, Tautz N6 Sakoda Y, Khromykh AA, Chayama K, Matsuura Y.
- Journal Title
  
  J Virol.
  
  Volume: 92 Issue: 2 Pages: 259-273
- DOI
  10.1128/jvi.01582-17
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-ORGANIZER-16H06429, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-16J02628, KAKENHI-INTERNATIONAL-16K21723, KAKENHI-PLANNED-16H06432
[Journal Article] Regulation of Apoptosis during Flavivirus Infection.2017
- Author(s)
  Okamoto T, Suzuki T, Kusakabe S, Tokunaga M, Hirano J, Miyata Y, Matsuura Y
- Journal Title
  
  Viruses
  
  Volume: 9 Issue: 9 Pages: 243-243
- DOI
  10.3390/v9090243
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-16K19139
[Journal Article] Characterization of SPP inhibitors suppressing propagation of HCV and protozoa2017
- Author(s)
  Hirano J, Okamoto T, Sugiyama Y, Suzuki T, Kusakabe S, Tokunaga M, Fukuhara T, Sasai M, Tougan T, Matsunaga Y, Yamashita K, Sakai Y, Yamamoto M, Horii T, Standley DM, Moriishi K, Moriya K, Koike K, Matsuura Y.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 114 Issue: 50
- DOI
  10.1073/pnas.1712484114
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08759, KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-15H04745
[Journal Article] Characterization of miR-122-independent propagation of HCV2017
- Author(s)
  Ono C., Fukuhara T., Motooka D., Nakamura S., Okuzaki D., Yamamoto S., Tamura T., Mori H., Sato A., Uemura K., Fauzyah Y., Kurihara T., Suda T., Nishino A., Hmwe SS., Okamoto T., Tatsumi T., Takehara T., Chayama K., Wakita T., Koike K., Matsuura Y.
- Journal Title
  
  PLoS Pathogens
  
  Volume: 13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04736
[Journal Article] Host-derived apolipoproteins play comparable roles with viral secretory proteins Erns and NS1 in the infectious particle formation of Flaviviridae2017
- Author(s)
  Takasuke Fukuhara, Tomokazu Tamura, Chikako Ono, Mai Shiokawa, Hiroyuki Mori, Kentaro Uemura, Satomi Yamamoto, Takeshi Kurihara, Toru Okamoto, Ryosuke Suzuki, Kentaro Yoshii, Takeshi Kurosu, Manabu Igarashi, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura
- Journal Title
  
  PLoS Pathogens
  
  Volume: 13
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04736
[Journal Article] Arid5a regulates naive CD4+ T cell fate through selective stabilization of Stat3 mRNA2016
- Author(s)
  Masuda, K., Ripley, B., Nyati, K., Dubey, P., Zaman, M., Hanieh, H., Hoga, M., Yamashita, K., Standley, D., Mashima, T., Katahira, M., Okamoto, T., Matsuura, Y., Takeuchi, O. and Kishimoto, T.
- Journal Title
  
  Journal of Experimental Medicine
  
  Volume: 213 Issue: 4 Pages: 605-619
- DOI
  10.1084/jem.20151289
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-15H00813, KAKENHI-PROJECT-26840020, KAKENHI-PROJECT-26860328, KAKENHI-PROJECT-15H04736
[Journal Article] Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity.2016
- Author(s)
  Fukuhara T, Yamamoto S, Ono C, Nakamura S, Motooka D, Mori H, Kurihara T, Sato A, Tamura T, Motomura T, Okamoto T, Imamura M, Ikegami T, Yoshizumi T, Soejima Y, Maehara Y, Chayama K, Matsuura Y.
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 45228-45228
- DOI
  10.1038/srep45228
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-ORGANIZER-16H06429, KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-16J02628
[Journal Article] 1TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis.2016
- Author(s)
  Aizawa S., Okamoto T., Sugiyama Y., Kouwaki T., Ito A., Suzuki T., Ono C., Fukuhara T., Yamamoto M., Okochi M., Hiraga N., Imamura M., Chayama K., Suzuki R., Shoji I., Moriishi K., Moriya K., Koike K., and Matsuura Y.
- Journal Title
  
  Nat. Commun.
  
  Volume: 未定
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H04736
[Journal Article] Inhibitory effect of CDK9 inhibitor FIT-039 on hepatitis B virus propagation2016
- Author(s)
  T. Tanaka, K. Okuyama-Dobashi, S. Murakami, W. Chen, T. Okamoto, K. Ueda, T. Hosoya, Y. Matsuura, A. Ryo, Y. Tanaka, M. Hagiwara and K. Moriishi
- Journal Title
  
  Antiviral Research
  
  Volume: 133 Pages: 156164-156164
- DOI
  10.1016/j.antiviral.2016.08.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-15K08493
[Journal Article] TRC8-dependent degradation of hepatitis C virus immature core protein regulates viral propagation and pathogenesis.2016
- Author(s)
  Aizawa S., Okamoto T., Sugiyama Y., Kouwaki T., Ito A., Suzuki T., Ono C., Fukuhara T., Yamamoto M., Okochi M., Hiraga N., Imamura M., Chayama K., Suzuki R., Shoji I., Moriishi K., Moriya K., Koike K., and Matsuura Y.
- Journal Title
  
  Nat. Commun.
  
  Volume: 7 Issue: 1 Pages: 1-12
- DOI
  10.1038/ncomms11379
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-16H06432, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-26461003
[Journal Article] Involvement of FKBP6 in hepatitis C virus replication2015
- Author(s)
  Kasai H, Kawakami Y, Yokoe H, Yoshimura K, Matsuda M, Yasumoto J, Maekawa S, Yamashita A, Tanaka T, Ikeda M, Kato N, Okamoto T, Matsuura Y, Sakamoto N, Enomoto N, Takeda S, Fujii H, Tsubuki M, Kusunoki M, Moriishi K.
- Journal Title
  
  Scientific reports
  
  Volume: 5 Issue: 1 Pages: 16699-16699
- DOI
  10.1038/srep16699
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08493, KAKENHI-PROJECT-15K15142, KAKENHI-PROJECT-15H04736, KAKENHI-PROJECT-25460985, KAKENHI-PROJECT-25293110, KAKENHI-PROJECT-25713023
[Journal Article] Enhanced Mcl1 stability can blunt stress-induced apoptosis, cause male sterility and promote tumorigenesis2014
- Author(s)
  Okamoto T, Coultas L, Metcalf D, van Delft M, Glasser SP, Takiguchi M, Strasser A, Bouillet P, Adams JM, Hunag DCS
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 111 Pages: 261-266
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890105
[Journal Article] Stabilizing the Pro-Apoptotic BimBH3 Helix (BimSAHB) Does Not Necessarily Enhance Affinity or Biological Activity2013
- Author(s)
  Okamoto T, Zobel K, Fedorova A, Quan C, Yang H, Fairbrother WJ, Huang DC, Smith BJ, Deshayes K, Czabotar PE
- Journal Title
  
  ACS Chemical Biology
  
  Volume: 8 Pages: 297-302
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890105
[Journal Article] Japanese Encephalitis Virus Core Protein Inhibits Stress Granule Formation through an Interaction with Caprin-1 and Facilitates Viral Propagation2012
- Author(s)
  Katoh H, Okamoto T, Fukuhara T, Kambara H, Morita E, Mori Y, Kamitani W, Matsuura Y
- Journal Title
  
  Jounal of Virology
  
  Volume: 87 Pages: 489-502
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890105
[Journal Article] Sheeppox Virus SPPV14 Encodes a Bcl-2-Like Cell Death Inhibitor That Counters a Distinct Set of Mammalian Proapoptotic Proteins2012
- Author(s)
  Okamoto T, Campbell S, Mehta N, Thibault J, Colman PM, Barry M, Huang DC, Kvansakul M
- Journal Title
  
  Journal of Virology
  
  Volume: 86 Pages: 11501-11511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24890105
[Presentation] ウイルスによる宿主への感染戦略2022
- Author(s)
  岡本徹
- Organizer
  第18回霊長類医科学フォーラム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03495
[Presentation] ウイルス感染における細胞死の制御2020
- Author(s)
  岡本徹
- Organizer
  第 93 回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03495
[Presentation] Viral secretory glycoproteins of Pestivirus and Flavivirus have similar roles with exchangeable apolipoproteins on the formation of infectious HCV particles2017
- Author(s)
  Takasuke Fukuhara, Tomokazu Tamura, Mai Shiokawa, Chikako Ono, Satomi Yamamoto Hiroyuki Mori, Asuka Sato, Shinya Yamada, Toru Okamoto, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura
- Organizer
  24th International Symposium on Heepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Characterization of selective autophagy induced by HCV RNA replication2017
- Author(s)
  Hiroyuki Mori, Takasuke Fukuhara, Chikako Ono, Tomokazu Tamura, Asuka Sato, Yuzy Fauzyah, Shinya Yamada, Toru Okamoto, Masami Wada, Takeshi Noda, Tamotsu Yoshimori, Yoshiharu Matsuura
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Ｃ型肝炎ウイルスの増殖と病原性に関与する宿主因子2017
- Author(s)
  松浦善治、福原崇介、岡本　徹
- Organizer
  北大部局横断シンポジウム第2回北大部局横断シンポジウム「免疫・癌・感染」
- Invited
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Engineering of Small Reporter-Tagged Flaviviridae Viruses Applicable to Antiviral Screening and in vivo Dynamics2017
- Author(s)
  Tomokazu Tamura, Takasuke Fukuhara, Akatuski Saito, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Tatuso Shioda, Kazuaki Chayama, Yoshiharu Matsuura
- Organizer
  24th International Symposium on Heepatitis C Virus and Related Viruses
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Engineering of small reporter-tagged Flaviviridae viruses applicable to antiviral screening and in vivo dynamics2017
- Author(s)
  Tomokazu Tamura, Takasuke Fukuhara, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Kazuaki Chayama, Yoshiharu Matsuura
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Viral secretory proteins Erns and NS1 play comparable roles with apolipoproteins in the infectious particle formation of Flaviviridae2017
- Author(s)
  Takasuke Fukuhara, Tomokazu Tamura, Mai Shiokawa, Chikako Ono, Satomi Yamamoto, Hiroyuki Mori, Takeshi Kurihara, Asuka Sato, Kentaro Uemura, Toru Okamoto, Hiroshi Aoki, Yoshihiro Sakoda, Yoshiharu Matsuura
- Organizer
  The American Society for Virology (ASV) the 36th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Involvement of other miRNA on the propagation of HCV in miR-1-deficient cells2017
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Kazuaki Chayama, Kazuhiko Koike, Yoshiharu Matsuura
- Organizer
  第65回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Ｃ型肝炎ウイルスの増殖と病原性に関与する宿主因子2017
- Author(s)
  Yoshiharu Matsuura, Takasuke Fukuhara, Toru Okamoto
- Organizer
  北大部局横断シンポジウム第2回北大部局横断シンポジウム「免疫・癌・感染」
- Place of Presentation
  北海道大学
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Characterization of Flaviviridae viruses possessing a reporter gene2017
- Author(s)
  Tomokazu Tamura, Takasuke Fukuhara, Chikako Ono, Hiroyuki Mori, Takeshi Kurihara, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Yoshiharu Matsuura
- Organizer
  The American Society for Virology (ASV) the 36th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] フラビウイルス感染におけるBcl-2ファミリー蛋白質の制御2017
- Author(s)
  岡本徹
- Organizer
  東京大学医科学研究所、若手研究者シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-16K19139
[Presentation] Characterization of recombinant Flaviviridae viruses possessing a small reporter-tag2017
- Author(s)
  Tomokazu Tamura, Takasuke Fukuhara, Takuro Uchida, Chikako Ono, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Takeshi Kurosu, Norbert Tautz, Yoshihiro Sakoda, Kazuaki Chayama, Yoshiharu Matsuura
- Organizer
  第16回あわじしま感染症・免疫フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Characterization of miR-122-independent propagation of HCV2017
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Kazuaki Chayama, Kazuhiko Koike, Yoshiharu Matsuura
- Organizer
  第16回あわじしま感染症・免疫フォーラム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Roles of miR-574-5p and miR-504-3p on the propagation of HCV in miR-122-deficient cells2017
- Author(s)
  Chikako Ono, Takasuke Fukuhara, Tomokazu Tamura, Hiroyuki Mori, Asuka Sato, Yuzy Fauzyah, Toru Okamoto, Kazuhiko Koike, Yoshiharu Matsuura
- Organizer
  The American Society for Virology (ASV) the 36th Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Evaluation of γ-secretase inhibitors for HCV therapy2016
- Author(s)
  Junki Hirano, Yukari Sugiyama, Tatsuya Suzuki, Shinji Kusakabe, Takasuke Fukuhara, Toru Okamoto, Yoshiharu Matsuura
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都国際会議場
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Signal peptide peptidase participates in propagation and pathogenesis of hepatitis C virus2016
- Author(s)
  Yoshiharu Matsuura, Toru Okamoto
- Organizer
  第64回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-10-23
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Single peptide peptidase a target for anti-HCV drug2016
- Author(s)
  Toru Okamoto,Junki Hirano,Tatsuya Suzuki, ,Shinji Kusakabe,Takasuke Fukuhara Kohji Moriishi,Kazuhiko Koike and Yoshiharu Matsuura
- Organizer
  23rd International Symposium on Hepatitis C Virus and Related Viruses
- Place of Presentation
  京都国際会議場
- Year and Date
  2016-10-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Signal peptide peptidase regulates propagation and pathogenesis of Hepatitis C Virus2015
- Author(s)
  Toru Okamoto,Yukari Sugiyama,Ayano Ito, Takasuke Fukuhara, and Yoshiharu Matusuura
- Organizer
  第14回あわじしま感染症免疫フォーラム
- Place of Presentation
  淡路市、兵庫県
- Year and Date
  2015-09-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] TRC8-dependent proteasome degradation of immature core protein participates in pathogenesis of HCV2015
- Author(s)
  Toru Okamoto, Yukari Sugiyama, Takahisa Kouwaki, Ayano Ito, Takasuke Fukuhara, Kohji Moriishi, Kazuhiko Koike, and Yoshiharu Matusuura
- Organizer
  The 22nd International Meeting on HCV and Related Viruses
- Place of Presentation
  Strasburg, France
- Year and Date
  2015-10-08
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] Processing of core protein by signal peptide peptidase participates in propagation and pathogenesis of hepatitis C virus2015
- Author(s)
  Toru Okamoto, Sayaka Aizawa, Yukari Sugiyama, Takahisa Kouwaki, Takasuke Fukuhara, Kohji Moriishi, Kazuhiko Koike, and Yoshiharu Matusuura
- Organizer
  The 34th Annual Meeting of the American Society for Virology
- Place of Presentation
  London, Canada
- Year and Date
  2015-07-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04736
[Presentation] 哺乳類オルソレオウイルスの腫瘍細胞溶解能の検討と遺伝子操作系の確立
- Author(s)
  川岸崇裕、金井祐太、岡本徹、松浦善治、小林剛
- Organizer
  第61回日本ウイルス学会学術集会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25860340

1. Matsuura Yoshiharu (50157252)

# of Collaborated Projects: 2 results

# of Collaborated Products: 25 results
2. KANAI YUTA (80506501)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. Kobayashi Takeshi (90324847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. FUKUHARA Takasuke (70598739)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
5. Sachiyo Yoshio (10774060)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 奥崎大介 (00346131)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 宮本洋一 (10379084)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. 南保明日香 (60359487)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 鈴木光幸 (90449059)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 須田亙 (20590847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 成島聖子 (80578336)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. Kawagishi Takahiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. HORII Toshihiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 鈴木信弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 真嶋司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 岡正啓

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 東岸任弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 野島聡

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

okamoto toru 岡本 徹

TORU OKAMOTO 岡本 徹

Okamoto Toru 岡本 徹

OKAMOTO Toru 岡本 徹

Research Projects

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Co-Researchers

膜界面生物学に基づくエボラウイルス複製の分子基盤

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Investigating MASH treatment strategies that emphasize the physiological roles of fatty acid-linked bile acids in the intestinal tract

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Immunoregulatory mechanisms in patients with LC-HCC

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Elucidation of protein translation shutoff by mosquito-borne flavivirusPrincipal Investigator

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Infection with flaviviruses requires BCLXL for cell survivalPrincipal Investigator

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Characterization of SPP involved in pathogenesis of HCV

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Development of replication-selective oncolytic viral vector using modified mammalian orthoreovirus

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Regulation of Bcl-2 protein family prtoteins by virus infectionPrincipal Investigator

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[Journal Article] Immunoglobulin-like transcript 2 as an impaired anti-tumor cytotoxicity marker of natural killer cells in patients with hepatocellular carcinoma2024

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[Journal Article] SARS-CoV-2 ORF6 disrupts nucleocytoplasmic trafficking to advance viral replication2022

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[Journal Article] Establishment of monoclonal antibodies broadly neutralize infection of hepatitis B virus.2022

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[Journal Article] Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 12021

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[Journal Article] Hepatitis C virus modulates signal peptide peptidase to alter host protein processing.2021

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okamoto toru 岡本徹

TORU OKAMOTO 岡本徹

Okamoto Toru 岡本徹

OKAMOTO Toru 岡本徹